FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3766, 504 aa 1>>>pF1KB3766 504 - 504 aa - 504 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.0506+/-0.000433; mu= 11.1633+/- 0.027 mean_var=145.5605+/-29.939, 0's: 0 Z-trim(114.4): 103 B-trim: 303 in 1/53 Lambda= 0.106305 statistics sampled from 24111 (24232) to 24111 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.639), E-opt: 0.2 (0.284), width: 16 Scan time: 7.930 The best scores are: opt bits E(85289) NP_006251 (OMIM: 601184,616192) dnaJ homolog subfa ( 504) 3318 521.0 3.1e-147 XP_016876163 (OMIM: 601184,616192) PREDICTED: dnaJ ( 421) 2782 438.8 1.5e-122 XP_011519406 (OMIM: 601184,616192) PREDICTED: dnaJ ( 533) 2519 398.5 2.5e-110 XP_011519407 (OMIM: 601184,616192) PREDICTED: dnaJ ( 450) 2506 396.5 8.7e-110 XP_016876164 (OMIM: 601184,616192) PREDICTED: dnaJ ( 383) 2503 395.9 1.1e-109 NP_003306 (OMIM: 601964) dnaJ homolog subfamily C ( 494) 638 110.0 1.6e-23 XP_011523469 (OMIM: 601964) PREDICTED: dnaJ homolo ( 438) 609 105.5 3.3e-22 XP_011523471 (OMIM: 601964) PREDICTED: dnaJ homolo ( 438) 609 105.5 3.3e-22 XP_011523470 (OMIM: 601964) PREDICTED: dnaJ homolo ( 438) 609 105.5 3.3e-22 NP_001138238 (OMIM: 601964) dnaJ homolog subfamily ( 438) 609 105.5 3.3e-22 XP_016880483 (OMIM: 601964) PREDICTED: dnaJ homolo ( 438) 609 105.5 3.3e-22 XP_016867122 (OMIM: 603511,611332) PREDICTED: dnaJ ( 211) 280 54.8 2.9e-07 NP_005485 (OMIM: 603511,611332) dnaJ homolog subfa ( 241) 280 54.8 3.2e-07 XP_006715886 (OMIM: 603511,611332) PREDICTED: dnaJ ( 257) 280 54.9 3.4e-07 NP_490647 (OMIM: 603511,611332) dnaJ homolog subfa ( 326) 280 54.9 4e-07 XP_011514006 (OMIM: 603511,611332) PREDICTED: dnaJ ( 334) 280 55.0 4.1e-07 XP_005249572 (OMIM: 603511,611332) PREDICTED: dnaJ ( 334) 280 55.0 4.1e-07 XP_005249573 (OMIM: 603511,611332) PREDICTED: dnaJ ( 334) 280 55.0 4.1e-07 XP_006713582 (OMIM: 611337) PREDICTED: dnaJ homolo ( 232) 266 52.7 1.4e-06 NP_699161 (OMIM: 611337) dnaJ homolog subfamily B ( 232) 266 52.7 1.4e-06 NP_057390 (OMIM: 611341) dnaJ homolog subfamily B ( 358) 251 50.5 9.4e-06 XP_006716814 (OMIM: 611328) PREDICTED: dnaJ homolo ( 348) 249 50.2 1.1e-05 XP_005251485 (OMIM: 611328) PREDICTED: dnaJ homolo ( 348) 249 50.2 1.1e-05 NP_036398 (OMIM: 611328) dnaJ homolog subfamily B ( 348) 249 50.2 1.1e-05 NP_660157 (OMIM: 611336) dnaJ homolog subfamily B ( 309) 248 50.0 1.2e-05 XP_011516144 (OMIM: 611328) PREDICTED: dnaJ homolo ( 420) 249 50.3 1.3e-05 NP_001128477 (OMIM: 611328) dnaJ homolog subfamily ( 420) 249 50.3 1.3e-05 NP_001128476 (OMIM: 611328) dnaJ homolog subfamily ( 462) 249 50.3 1.4e-05 XP_005269989 (OMIM: 608376) PREDICTED: dnaJ homolo ( 409) 246 49.8 1.8e-05 NP_060096 (OMIM: 608376) dnaJ homolog subfamily B ( 409) 246 49.8 1.8e-05 NP_001002762 (OMIM: 608376) dnaJ homolog subfamily ( 409) 246 49.8 1.8e-05 XP_005269988 (OMIM: 608376) PREDICTED: dnaJ homolo ( 411) 246 49.8 1.8e-05 NP_001034639 (OMIM: 604139,614881,617017) dnaJ hom ( 277) 243 49.2 1.8e-05 NP_006727 (OMIM: 604139,614881,617017) dnaJ homolo ( 324) 243 49.3 2.1e-05 NP_001304028 (OMIM: 611327) dnaJ homolog subfamily ( 337) 231 47.4 7.6e-05 NP_008965 (OMIM: 611327) dnaJ homolog subfamily B ( 337) 231 47.4 7.6e-05 NP_006136 (OMIM: 604572) dnaJ homolog subfamily B ( 340) 229 47.1 9.4e-05 NP_036460 (OMIM: 602634) dnaJ homolog subfamily B ( 223) 225 46.4 0.00011 NP_001128582 (OMIM: 608382) dnaJ homolog subfamily ( 453) 226 46.8 0.00016 NP_005138 (OMIM: 608382) dnaJ homolog subfamily A ( 480) 226 46.8 0.00017 NP_001530 (OMIM: 602837) dnaJ homolog subfamily A ( 397) 224 46.4 0.00018 NP_001304032 (OMIM: 611327) dnaJ homolog subfamily ( 77) 211 43.8 0.00021 NP_001012339 (OMIM: 617048,617052) dnaJ homolog su ( 531) 214 45.0 0.00065 XP_005248307 (OMIM: 617048,617052) PREDICTED: dnaJ ( 553) 214 45.0 0.00067 NP_919259 (OMIM: 617048,617052) dnaJ homolog subfa ( 576) 214 45.0 0.00069 XP_011512268 (OMIM: 617048,617052) PREDICTED: dnaJ ( 598) 214 45.0 0.00071 XP_005248306 (OMIM: 617048,617052) PREDICTED: dnaJ ( 631) 214 45.1 0.00074 XP_011512267 (OMIM: 617048,617052) PREDICTED: dnaJ ( 676) 214 45.1 0.00078 NP_001139547 (OMIM: 611477) RNA polymerase II-asso ( 631) 209 44.3 0.0013 NP_078880 (OMIM: 611477) RNA polymerase II-associa ( 665) 209 44.3 0.0013 >>NP_006251 (OMIM: 601184,616192) dnaJ homolog subfamily (504 aa) initn: 3318 init1: 3318 opt: 3318 Z-score: 2764.3 bits: 521.0 E(85289): 3.1e-147 Smith-Waterman score: 3318; 100.0% identity (100.0% similar) in 504 aa overlap (1-504:1-504) 10 20 30 40 50 60 pF1KB3 MVAPGSVTSRLGSVFPFLLVLVDLQYEGAECGVNADVEKHLELGKKLLAAGQLADALSQF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 MVAPGSVTSRLGSVFPFLLVLVDLQYEGAECGVNADVEKHLELGKKLLAAGQLADALSQF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 HAAVDGDPDNYIAYYRRATVFLAMGKSKAALPDLTKVIQLKMDFTAARLQRGHLLLKQGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 HAAVDGDPDNYIAYYRRATVFLAMGKSKAALPDLTKVIQLKMDFTAARLQRGHLLLKQGK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 LDEAEDDFKKVLKSNPSENEEKEAQSQLIKSDEMQRLRSQALNAFGSGDYTAAIAFLDKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 LDEAEDDFKKVLKSNPSENEEKEAQSQLIKSDEMQRLRSQALNAFGSGDYTAAIAFLDKI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 LEVCVWDAELRELRAECFIKEGEPRKAISDLKAASKLKNDNTEAFYKISTLYYQLGDHEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 LEVCVWDAELRELRAECFIKEGEPRKAISDLKAASKLKNDNTEAFYKISTLYYQLGDHEL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 SLSEVRECLKLDQDHKRCFAHYKQVKKLNKLIESAEELIRDGRYTDATSKYESVMKTEPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 SLSEVRECLKLDQDHKRCFAHYKQVKKLNKLIESAEELIRDGRYTDATSKYESVMKTEPS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 IAEYTVRSKERICHCFSKDEKPVEAIRVCSEVLQMEPDNVNALKDRAEAYLIEEMYDEAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 IAEYTVRSKERICHCFSKDEKPVEAIRVCSEVLQMEPDNVNALKDRAEAYLIEEMYDEAI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 QDYETAQEHNENDQQIREGLEKAQRLLKQSQKRDYYKILGVKRNAKKQEIIKAYRKLALQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 QDYETAQEHNENDQQIREGLEKAQRLLKQSQKRDYYKILGVKRNAKKQEIIKAYRKLALQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 WHPDNFQNEEEKKKAEKKFIDIAAAKEVLSDPEMRKKFDDGEDPLDAESQQGGGGNPFHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 WHPDNFQNEEEKKKAEKKFIDIAAAKEVLSDPEMRKKFDDGEDPLDAESQQGGGGNPFHR 430 440 450 460 470 480 490 500 pF1KB3 SWNSWQGFNPFSSGGPFRFKFHFN :::::::::::::::::::::::: NP_006 SWNSWQGFNPFSSGGPFRFKFHFN 490 500 >>XP_016876163 (OMIM: 601184,616192) PREDICTED: dnaJ hom (421 aa) initn: 2782 init1: 2782 opt: 2782 Z-score: 2321.1 bits: 438.8 E(85289): 1.5e-122 Smith-Waterman score: 2782; 100.0% identity (100.0% similar) in 421 aa overlap (84-504:1-421) 60 70 80 90 100 110 pF1KB3 ADALSQFHAAVDGDPDNYIAYYRRATVFLAMGKSKAALPDLTKVIQLKMDFTAARLQRGH :::::::::::::::::::::::::::::: XP_016 MGKSKAALPDLTKVIQLKMDFTAARLQRGH 10 20 30 120 130 140 150 160 170 pF1KB3 LLLKQGKLDEAEDDFKKVLKSNPSENEEKEAQSQLIKSDEMQRLRSQALNAFGSGDYTAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLLKQGKLDEAEDDFKKVLKSNPSENEEKEAQSQLIKSDEMQRLRSQALNAFGSGDYTAA 40 50 60 70 80 90 180 190 200 210 220 230 pF1KB3 IAFLDKILEVCVWDAELRELRAECFIKEGEPRKAISDLKAASKLKNDNTEAFYKISTLYY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IAFLDKILEVCVWDAELRELRAECFIKEGEPRKAISDLKAASKLKNDNTEAFYKISTLYY 100 110 120 130 140 150 240 250 260 270 280 290 pF1KB3 QLGDHELSLSEVRECLKLDQDHKRCFAHYKQVKKLNKLIESAEELIRDGRYTDATSKYES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QLGDHELSLSEVRECLKLDQDHKRCFAHYKQVKKLNKLIESAEELIRDGRYTDATSKYES 160 170 180 190 200 210 300 310 320 330 340 350 pF1KB3 VMKTEPSIAEYTVRSKERICHCFSKDEKPVEAIRVCSEVLQMEPDNVNALKDRAEAYLIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VMKTEPSIAEYTVRSKERICHCFSKDEKPVEAIRVCSEVLQMEPDNVNALKDRAEAYLIE 220 230 240 250 260 270 360 370 380 390 400 410 pF1KB3 EMYDEAIQDYETAQEHNENDQQIREGLEKAQRLLKQSQKRDYYKILGVKRNAKKQEIIKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EMYDEAIQDYETAQEHNENDQQIREGLEKAQRLLKQSQKRDYYKILGVKRNAKKQEIIKA 280 290 300 310 320 330 420 430 440 450 460 470 pF1KB3 YRKLALQWHPDNFQNEEEKKKAEKKFIDIAAAKEVLSDPEMRKKFDDGEDPLDAESQQGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YRKLALQWHPDNFQNEEEKKKAEKKFIDIAAAKEVLSDPEMRKKFDDGEDPLDAESQQGG 340 350 360 370 380 390 480 490 500 pF1KB3 GGNPFHRSWNSWQGFNPFSSGGPFRFKFHFN ::::::::::::::::::::::::::::::: XP_016 GGNPFHRSWNSWQGFNPFSSGGPFRFKFHFN 400 410 420 >>XP_011519406 (OMIM: 601184,616192) PREDICTED: dnaJ hom (533 aa) initn: 2481 init1: 2481 opt: 2519 Z-score: 2101.8 bits: 398.5 E(85289): 2.5e-110 Smith-Waterman score: 3250; 94.6% identity (94.6% similar) in 533 aa overlap (1-504:1-533) 10 20 30 40 50 60 pF1KB3 MVAPGSVTSRLGSVFPFLLVLVDLQYEGAECGVNADVEKHLELGKKLLAAGQLADALSQF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MVAPGSVTSRLGSVFPFLLVLVDLQYEGAECGVNADVEKHLELGKKLLAAGQLADALSQF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 HAAVDGDPDNYIAYYRRATVFLAMGKSKAALPDLTKVIQLKMDFTAARLQRGHLLLKQGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HAAVDGDPDNYIAYYRRATVFLAMGKSKAALPDLTKVIQLKMDFTAARLQRGHLLLKQGK 70 80 90 100 110 120 130 140 150 pF1KB3 LDEAEDDFKKV-----------------------------LKSNPSENEEKEAQSQLIKS ::::::::::: :::::::::::::::::::: XP_011 LDEAEDDFKKVVFPVPSLLGLQRSLLDDLYLLFWFFLMKKLKSNPSENEEKEAQSQLIKS 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB3 DEMQRLRSQALNAFGSGDYTAAIAFLDKILEVCVWDAELRELRAECFIKEGEPRKAISDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DEMQRLRSQALNAFGSGDYTAAIAFLDKILEVCVWDAELRELRAECFIKEGEPRKAISDL 190 200 210 220 230 240 220 230 240 250 260 270 pF1KB3 KAASKLKNDNTEAFYKISTLYYQLGDHELSLSEVRECLKLDQDHKRCFAHYKQVKKLNKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KAASKLKNDNTEAFYKISTLYYQLGDHELSLSEVRECLKLDQDHKRCFAHYKQVKKLNKL 250 260 270 280 290 300 280 290 300 310 320 330 pF1KB3 IESAEELIRDGRYTDATSKYESVMKTEPSIAEYTVRSKERICHCFSKDEKPVEAIRVCSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IESAEELIRDGRYTDATSKYESVMKTEPSIAEYTVRSKERICHCFSKDEKPVEAIRVCSE 310 320 330 340 350 360 340 350 360 370 380 390 pF1KB3 VLQMEPDNVNALKDRAEAYLIEEMYDEAIQDYETAQEHNENDQQIREGLEKAQRLLKQSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VLQMEPDNVNALKDRAEAYLIEEMYDEAIQDYETAQEHNENDQQIREGLEKAQRLLKQSQ 370 380 390 400 410 420 400 410 420 430 440 450 pF1KB3 KRDYYKILGVKRNAKKQEIIKAYRKLALQWHPDNFQNEEEKKKAEKKFIDIAAAKEVLSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KRDYYKILGVKRNAKKQEIIKAYRKLALQWHPDNFQNEEEKKKAEKKFIDIAAAKEVLSD 430 440 450 460 470 480 460 470 480 490 500 pF1KB3 PEMRKKFDDGEDPLDAESQQGGGGNPFHRSWNSWQGFNPFSSGGPFRFKFHFN ::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PEMRKKFDDGEDPLDAESQQGGGGNPFHRSWNSWQGFNPFSSGGPFRFKFHFN 490 500 510 520 530 >>XP_011519407 (OMIM: 601184,616192) PREDICTED: dnaJ hom (450 aa) initn: 2481 init1: 2481 opt: 2506 Z-score: 2092.0 bits: 396.5 E(85289): 8.7e-110 Smith-Waterman score: 2714; 93.6% identity (93.6% similar) in 450 aa overlap (84-504:1-450) 60 70 80 90 100 110 pF1KB3 ADALSQFHAAVDGDPDNYIAYYRRATVFLAMGKSKAALPDLTKVIQLKMDFTAARLQRGH :::::::::::::::::::::::::::::: XP_011 MGKSKAALPDLTKVIQLKMDFTAARLQRGH 10 20 30 120 130 140 pF1KB3 LLLKQGKLDEAEDDFKKV-----------------------------LKSNPSENEEKEA :::::::::::::::::: ::::::::::::: XP_011 LLLKQGKLDEAEDDFKKVVFPVPSLLGLQRSLLDDLYLLFWFFLMKKLKSNPSENEEKEA 40 50 60 70 80 90 150 160 170 180 190 200 pF1KB3 QSQLIKSDEMQRLRSQALNAFGSGDYTAAIAFLDKILEVCVWDAELRELRAECFIKEGEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QSQLIKSDEMQRLRSQALNAFGSGDYTAAIAFLDKILEVCVWDAELRELRAECFIKEGEP 100 110 120 130 140 150 210 220 230 240 250 260 pF1KB3 RKAISDLKAASKLKNDNTEAFYKISTLYYQLGDHELSLSEVRECLKLDQDHKRCFAHYKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RKAISDLKAASKLKNDNTEAFYKISTLYYQLGDHELSLSEVRECLKLDQDHKRCFAHYKQ 160 170 180 190 200 210 270 280 290 300 310 320 pF1KB3 VKKLNKLIESAEELIRDGRYTDATSKYESVMKTEPSIAEYTVRSKERICHCFSKDEKPVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VKKLNKLIESAEELIRDGRYTDATSKYESVMKTEPSIAEYTVRSKERICHCFSKDEKPVE 220 230 240 250 260 270 330 340 350 360 370 380 pF1KB3 AIRVCSEVLQMEPDNVNALKDRAEAYLIEEMYDEAIQDYETAQEHNENDQQIREGLEKAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AIRVCSEVLQMEPDNVNALKDRAEAYLIEEMYDEAIQDYETAQEHNENDQQIREGLEKAQ 280 290 300 310 320 330 390 400 410 420 430 440 pF1KB3 RLLKQSQKRDYYKILGVKRNAKKQEIIKAYRKLALQWHPDNFQNEEEKKKAEKKFIDIAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RLLKQSQKRDYYKILGVKRNAKKQEIIKAYRKLALQWHPDNFQNEEEKKKAEKKFIDIAA 340 350 360 370 380 390 450 460 470 480 490 500 pF1KB3 AKEVLSDPEMRKKFDDGEDPLDAESQQGGGGNPFHRSWNSWQGFNPFSSGGPFRFKFHFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AKEVLSDPEMRKKFDDGEDPLDAESQQGGGGNPFHRSWNSWQGFNPFSSGGPFRFKFHFN 400 410 420 430 440 450 >>XP_016876164 (OMIM: 601184,616192) PREDICTED: dnaJ hom (383 aa) initn: 2503 init1: 2503 opt: 2503 Z-score: 2090.4 bits: 395.9 E(85289): 1.1e-109 Smith-Waterman score: 2503; 100.0% identity (100.0% similar) in 377 aa overlap (128-504:7-383) 100 110 120 130 140 150 pF1KB3 IQLKMDFTAARLQRGHLLLKQGKLDEAEDDFKKVLKSNPSENEEKEAQSQLIKSDEMQRL :::::::::::::::::::::::::::::: XP_016 MCFLHFFKKVLKSNPSENEEKEAQSQLIKSDEMQRL 10 20 30 160 170 180 190 200 210 pF1KB3 RSQALNAFGSGDYTAAIAFLDKILEVCVWDAELRELRAECFIKEGEPRKAISDLKAASKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RSQALNAFGSGDYTAAIAFLDKILEVCVWDAELRELRAECFIKEGEPRKAISDLKAASKL 40 50 60 70 80 90 220 230 240 250 260 270 pF1KB3 KNDNTEAFYKISTLYYQLGDHELSLSEVRECLKLDQDHKRCFAHYKQVKKLNKLIESAEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KNDNTEAFYKISTLYYQLGDHELSLSEVRECLKLDQDHKRCFAHYKQVKKLNKLIESAEE 100 110 120 130 140 150 280 290 300 310 320 330 pF1KB3 LIRDGRYTDATSKYESVMKTEPSIAEYTVRSKERICHCFSKDEKPVEAIRVCSEVLQMEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LIRDGRYTDATSKYESVMKTEPSIAEYTVRSKERICHCFSKDEKPVEAIRVCSEVLQMEP 160 170 180 190 200 210 340 350 360 370 380 390 pF1KB3 DNVNALKDRAEAYLIEEMYDEAIQDYETAQEHNENDQQIREGLEKAQRLLKQSQKRDYYK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DNVNALKDRAEAYLIEEMYDEAIQDYETAQEHNENDQQIREGLEKAQRLLKQSQKRDYYK 220 230 240 250 260 270 400 410 420 430 440 450 pF1KB3 ILGVKRNAKKQEIIKAYRKLALQWHPDNFQNEEEKKKAEKKFIDIAAAKEVLSDPEMRKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ILGVKRNAKKQEIIKAYRKLALQWHPDNFQNEEEKKKAEKKFIDIAAAKEVLSDPEMRKK 280 290 300 310 320 330 460 470 480 490 500 pF1KB3 FDDGEDPLDAESQQGGGGNPFHRSWNSWQGFNPFSSGGPFRFKFHFN ::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FDDGEDPLDAESQQGGGGNPFHRSWNSWQGFNPFSSGGPFRFKFHFN 340 350 360 370 380 >>NP_003306 (OMIM: 601964) dnaJ homolog subfamily C memb (494 aa) initn: 323 init1: 187 opt: 638 Z-score: 543.1 bits: 110.0 E(85289): 1.6e-23 Smith-Waterman score: 638; 28.2% identity (62.8% similar) in 479 aa overlap (36-503:27-493) 10 20 30 40 50 60 pF1KB3 SVTSRLGSVFPFLLVLVDLQYEGAECGVNADVEKHLELGKKLLAAGQLADALSQFHAAVD ..: : :. : . .: . . :.: NP_003 MAAAAECDVVMAATEPELLDDQEAKREAETFKEQGNAYYAKKDYNEAYNYYTKAID 10 20 30 40 50 70 80 90 100 110 120 pF1KB3 GDPDNYIAYYRRATVFLAMGKSKAALPDLTKVIQLKMDFTAARLQRGHLLLKQGKLDEAE : : : ::.... .:. . :: : . ..: .:. ..:..:. :. :. : NP_003 MCPKNASYYGNRAATLMMLGRFREALGDAQQSVRLDDSFVRGHLREGKCHLSLGNAMAAC 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB3 DDFKKVLKSNPSENEEKEAQSQLIKSDEMQRLRSQALNAFGSGDYTAAIAFLDKILEVCV .:...:. .... .::... ... ... .. : . : . :. .. .:. :: NP_003 RSFQRALEL---DHKNAQAQQEFKNANAVMEYEKIAETDFEKRDFRKVVFCMDRALEFAP 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB3 WDAELRELRAECFIKEGEPRKAISDLKAASKLKNDNTEAFY-KISTLYYQLGDHELSLSE ... :.:::. :. .: : . .. . :..:.: . :::. : ... NP_003 ACHRFKILKAECLAMLGRYPEAQSVASDILRMDSTNADALYVRGLCLYYE-DCIEKAVQF 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB3 VRECLKLDQDHKR-CFAHYKQVKKLNKLIESAEELIRDGRYTDATSKYESVMKTEPSIAE . :.. ::.. :.: ...: :. :.... ...: : : : .. .:. NP_003 FVQALRMAPDHEKACIAC-RNAKALKAKKEDGNKAFKEGNYKLAYELYTEALGIDPN--- 240 250 260 270 280 310 320 330 340 350 pF1KB3 YTVRSKERI-CH---CFSKDEKPVEAIRVCSEVLQMEPDNVNALKDRAEAYLIEEMYDEA ..... .. :. :: .: .::. :....... ..: ::. :. :.:.:: NP_003 -NIKTNAKLYCNRGTVNSKLRKLDDAIEDCTNAVKLDDTYIKAYLRRAQCYMDTEQYEEA 290 300 310 320 330 340 360 370 380 390 400 410 pF1KB3 IQDYETAQEHNENDQQIREGLEKAQRLLKQSQKRDYYKILGVKRNAKKQEIIKAYRKLAL ..::: . . .:. .. .. :..:: ::.:...:::::::: .::...:: ::::: :: NP_003 VRDYEKVYQ-TEKTKEHKQLLKNAQLELKKSKRKDYYKILGVDKNASEDEIKKAYRKRAL 350 360 370 380 390 400 420 430 440 450 460 470 pF1KB3 QWHPDNFQ--NEEEKKKAEKKFIDIAAAKEVLSDPEMRKKFDDGEDPLDAESQQGGGGNP . ::: . . : .:. :::: ... : .::::. . ..:.:.: :: :... : .: NP_003 MHHPDRHSGASAEVQKEEEKKFKEVGEAFTILSDPKKKTRYDSGQD-LDEEGMNMGDFDP 410 420 430 440 450 460 480 490 500 pF1KB3 ---FHRSWNSWQGFNPFSSGGPFRFKFHFN :. ... ::. : ..:: : :.: NP_003 NNIFKAFFGGPGGFS-FEASGPGNFFFQFG 470 480 490 >>XP_011523469 (OMIM: 601964) PREDICTED: dnaJ homolog su (438 aa) initn: 323 init1: 187 opt: 609 Z-score: 519.8 bits: 105.5 E(85289): 3.3e-22 Smith-Waterman score: 609; 28.8% identity (64.1% similar) in 448 aa overlap (68-503:3-437) 40 50 60 70 80 90 pF1KB3 EKHLELGKKLLAAGQLADALSQFHAAVDGDPDNYIAYYRRATVFLAMGKSKAALPDLTKV : : : ::.... .:. . :: : . XP_011 MCPKNASYYGNRAATLMMLGRFREALGDAQQS 10 20 30 100 110 120 130 140 150 pF1KB3 IQLKMDFTAARLQRGHLLLKQGKLDEAEDDFKKVLKSNPSENEEKEAQSQLIKSDEMQRL ..: .:. ..:..:. :. :. : .:...:. .... .::... ... ... XP_011 VRLDDSFVRGHLREGKCHLSLGNAMAACRSFQRALEL---DHKNAQAQQEFKNANAVMEY 40 50 60 70 80 160 170 180 190 200 210 pF1KB3 RSQALNAFGSGDYTAAIAFLDKILEVCVWDAELRELRAECFIKEGEPRKAISDLKAASKL .. : . : . :. .. .:. :: ... :.:::. :. .: : . .. XP_011 EKIAETDFEKRDFRKVVFCMDRALEFAPACHRFKILKAECLAMLGRYPEAQSVASDILRM 90 100 110 120 130 140 220 230 240 250 260 270 pF1KB3 KNDNTEAFY-KISTLYYQLGDH-ELSLSEVRECLKLDQDHKR-CFAHYKQVKKLNKLIES . :..:.: . :::. : : ... . :.. ::.. :.: ...: :. :. XP_011 DSTNADALYVRGLCLYYE--DCIEKAVQFFVQALRMAPDHEKACIAC-RNAKALKAKKED 150 160 170 180 190 200 280 290 300 310 320 330 pF1KB3 AEELIRDGRYTDATSKYESVMKTEPSIAEYTVRSKERI-CH---CFSKDEKPVEAIRVCS ... ...: : : : .. .:. ..... .. :. :: .: .::. :. XP_011 GNKAFKEGNYKLAYELYTEALGIDPN----NIKTNAKLYCNRGTVNSKLRKLDDAIEDCT 210 220 230 240 250 260 340 350 360 370 380 390 pF1KB3 EVLQMEPDNVNALKDRAEAYLIEEMYDEAIQDYETAQEHNENDQQIREGLEKAQRLLKQS ...... ..: ::. :. :.:.::..::: . . .:. .. .. :..:: ::.: XP_011 NAVKLDDTYIKAYLRRAQCYMDTEQYEEAVRDYEKVYQ-TEKTKEHKQLLKNAQLELKKS 270 280 290 300 310 320 400 410 420 430 440 pF1KB3 QKRDYYKILGVKRNAKKQEIIKAYRKLALQWHPDNFQ--NEEEKKKAEKKFIDIAAAKEV ...:::::::: .::...:: ::::: ::. ::: . . : .:. :::: ... : . XP_011 KRKDYYKILGVDKNASEDEIKKAYRKRALMHHPDRHSGASAEVQKEEEKKFKEVGEAFTI 330 340 350 360 370 380 450 460 470 480 490 500 pF1KB3 LSDPEMRKKFDDGEDPLDAESQQGGGGNP---FHRSWNSWQGFNPFSSGGPFRFKFHFN ::::. . ..:.:.: :: :... : .: :. ... ::. : ..:: : :.: XP_011 LSDPKKKTRYDSGQD-LDEEGMNMGDFDPNNIFKAFFGGPGGFS-FEASGPGNFFFQFG 390 400 410 420 430 >>XP_011523471 (OMIM: 601964) PREDICTED: dnaJ homolog su (438 aa) initn: 323 init1: 187 opt: 609 Z-score: 519.8 bits: 105.5 E(85289): 3.3e-22 Smith-Waterman score: 609; 28.8% identity (64.1% similar) in 448 aa overlap (68-503:3-437) 40 50 60 70 80 90 pF1KB3 EKHLELGKKLLAAGQLADALSQFHAAVDGDPDNYIAYYRRATVFLAMGKSKAALPDLTKV : : : ::.... .:. . :: : . XP_011 MCPKNASYYGNRAATLMMLGRFREALGDAQQS 10 20 30 100 110 120 130 140 150 pF1KB3 IQLKMDFTAARLQRGHLLLKQGKLDEAEDDFKKVLKSNPSENEEKEAQSQLIKSDEMQRL ..: .:. ..:..:. :. :. : .:...:. .... .::... ... ... XP_011 VRLDDSFVRGHLREGKCHLSLGNAMAACRSFQRALEL---DHKNAQAQQEFKNANAVMEY 40 50 60 70 80 160 170 180 190 200 210 pF1KB3 RSQALNAFGSGDYTAAIAFLDKILEVCVWDAELRELRAECFIKEGEPRKAISDLKAASKL .. : . : . :. .. .:. :: ... :.:::. :. .: : . .. XP_011 EKIAETDFEKRDFRKVVFCMDRALEFAPACHRFKILKAECLAMLGRYPEAQSVASDILRM 90 100 110 120 130 140 220 230 240 250 260 270 pF1KB3 KNDNTEAFY-KISTLYYQLGDH-ELSLSEVRECLKLDQDHKR-CFAHYKQVKKLNKLIES . :..:.: . :::. : : ... . :.. ::.. :.: ...: :. :. XP_011 DSTNADALYVRGLCLYYE--DCIEKAVQFFVQALRMAPDHEKACIAC-RNAKALKAKKED 150 160 170 180 190 200 280 290 300 310 320 330 pF1KB3 AEELIRDGRYTDATSKYESVMKTEPSIAEYTVRSKERI-CH---CFSKDEKPVEAIRVCS ... ...: : : : .. .:. ..... .. :. :: .: .::. :. XP_011 GNKAFKEGNYKLAYELYTEALGIDPN----NIKTNAKLYCNRGTVNSKLRKLDDAIEDCT 210 220 230 240 250 260 340 350 360 370 380 390 pF1KB3 EVLQMEPDNVNALKDRAEAYLIEEMYDEAIQDYETAQEHNENDQQIREGLEKAQRLLKQS ...... ..: ::. :. :.:.::..::: . . .:. .. .. :..:: ::.: XP_011 NAVKLDDTYIKAYLRRAQCYMDTEQYEEAVRDYEKVYQ-TEKTKEHKQLLKNAQLELKKS 270 280 290 300 310 320 400 410 420 430 440 pF1KB3 QKRDYYKILGVKRNAKKQEIIKAYRKLALQWHPDNFQ--NEEEKKKAEKKFIDIAAAKEV ...:::::::: .::...:: ::::: ::. ::: . . : .:. :::: ... : . XP_011 KRKDYYKILGVDKNASEDEIKKAYRKRALMHHPDRHSGASAEVQKEEEKKFKEVGEAFTI 330 340 350 360 370 380 450 460 470 480 490 500 pF1KB3 LSDPEMRKKFDDGEDPLDAESQQGGGGNP---FHRSWNSWQGFNPFSSGGPFRFKFHFN ::::. . ..:.:.: :: :... : .: :. ... ::. : ..:: : :.: XP_011 LSDPKKKTRYDSGQD-LDEEGMNMGDFDPNNIFKAFFGGPGGFS-FEASGPGNFFFQFG 390 400 410 420 430 >>XP_011523470 (OMIM: 601964) PREDICTED: dnaJ homolog su (438 aa) initn: 323 init1: 187 opt: 609 Z-score: 519.8 bits: 105.5 E(85289): 3.3e-22 Smith-Waterman score: 609; 28.8% identity (64.1% similar) in 448 aa overlap (68-503:3-437) 40 50 60 70 80 90 pF1KB3 EKHLELGKKLLAAGQLADALSQFHAAVDGDPDNYIAYYRRATVFLAMGKSKAALPDLTKV : : : ::.... .:. . :: : . XP_011 MCPKNASYYGNRAATLMMLGRFREALGDAQQS 10 20 30 100 110 120 130 140 150 pF1KB3 IQLKMDFTAARLQRGHLLLKQGKLDEAEDDFKKVLKSNPSENEEKEAQSQLIKSDEMQRL ..: .:. ..:..:. :. :. : .:...:. .... .::... ... ... XP_011 VRLDDSFVRGHLREGKCHLSLGNAMAACRSFQRALEL---DHKNAQAQQEFKNANAVMEY 40 50 60 70 80 160 170 180 190 200 210 pF1KB3 RSQALNAFGSGDYTAAIAFLDKILEVCVWDAELRELRAECFIKEGEPRKAISDLKAASKL .. : . : . :. .. .:. :: ... :.:::. :. .: : . .. XP_011 EKIAETDFEKRDFRKVVFCMDRALEFAPACHRFKILKAECLAMLGRYPEAQSVASDILRM 90 100 110 120 130 140 220 230 240 250 260 270 pF1KB3 KNDNTEAFY-KISTLYYQLGDH-ELSLSEVRECLKLDQDHKR-CFAHYKQVKKLNKLIES . :..:.: . :::. : : ... . :.. ::.. :.: ...: :. :. XP_011 DSTNADALYVRGLCLYYE--DCIEKAVQFFVQALRMAPDHEKACIAC-RNAKALKAKKED 150 160 170 180 190 200 280 290 300 310 320 330 pF1KB3 AEELIRDGRYTDATSKYESVMKTEPSIAEYTVRSKERI-CH---CFSKDEKPVEAIRVCS ... ...: : : : .. .:. ..... .. :. :: .: .::. :. XP_011 GNKAFKEGNYKLAYELYTEALGIDPN----NIKTNAKLYCNRGTVNSKLRKLDDAIEDCT 210 220 230 240 250 260 340 350 360 370 380 390 pF1KB3 EVLQMEPDNVNALKDRAEAYLIEEMYDEAIQDYETAQEHNENDQQIREGLEKAQRLLKQS ...... ..: ::. :. :.:.::..::: . . .:. .. .. :..:: ::.: XP_011 NAVKLDDTYIKAYLRRAQCYMDTEQYEEAVRDYEKVYQ-TEKTKEHKQLLKNAQLELKKS 270 280 290 300 310 320 400 410 420 430 440 pF1KB3 QKRDYYKILGVKRNAKKQEIIKAYRKLALQWHPDNFQ--NEEEKKKAEKKFIDIAAAKEV ...:::::::: .::...:: ::::: ::. ::: . . : .:. :::: ... : . XP_011 KRKDYYKILGVDKNASEDEIKKAYRKRALMHHPDRHSGASAEVQKEEEKKFKEVGEAFTI 330 340 350 360 370 380 450 460 470 480 490 500 pF1KB3 LSDPEMRKKFDDGEDPLDAESQQGGGGNP---FHRSWNSWQGFNPFSSGGPFRFKFHFN ::::. . ..:.:.: :: :... : .: :. ... ::. : ..:: : :.: XP_011 LSDPKKKTRYDSGQD-LDEEGMNMGDFDPNNIFKAFFGGPGGFS-FEASGPGNFFFQFG 390 400 410 420 430 >>NP_001138238 (OMIM: 601964) dnaJ homolog subfamily C m (438 aa) initn: 323 init1: 187 opt: 609 Z-score: 519.8 bits: 105.5 E(85289): 3.3e-22 Smith-Waterman score: 609; 28.8% identity (64.1% similar) in 448 aa overlap (68-503:3-437) 40 50 60 70 80 90 pF1KB3 EKHLELGKKLLAAGQLADALSQFHAAVDGDPDNYIAYYRRATVFLAMGKSKAALPDLTKV : : : ::.... .:. . :: : . NP_001 MCPKNASYYGNRAATLMMLGRFREALGDAQQS 10 20 30 100 110 120 130 140 150 pF1KB3 IQLKMDFTAARLQRGHLLLKQGKLDEAEDDFKKVLKSNPSENEEKEAQSQLIKSDEMQRL ..: .:. ..:..:. :. :. : .:...:. .... .::... ... ... NP_001 VRLDDSFVRGHLREGKCHLSLGNAMAACRSFQRALEL---DHKNAQAQQEFKNANAVMEY 40 50 60 70 80 160 170 180 190 200 210 pF1KB3 RSQALNAFGSGDYTAAIAFLDKILEVCVWDAELRELRAECFIKEGEPRKAISDLKAASKL .. : . : . :. .. .:. :: ... :.:::. :. .: : . .. NP_001 EKIAETDFEKRDFRKVVFCMDRALEFAPACHRFKILKAECLAMLGRYPEAQSVASDILRM 90 100 110 120 130 140 220 230 240 250 260 270 pF1KB3 KNDNTEAFY-KISTLYYQLGDH-ELSLSEVRECLKLDQDHKR-CFAHYKQVKKLNKLIES . :..:.: . :::. : : ... . :.. ::.. :.: ...: :. :. NP_001 DSTNADALYVRGLCLYYE--DCIEKAVQFFVQALRMAPDHEKACIAC-RNAKALKAKKED 150 160 170 180 190 200 280 290 300 310 320 330 pF1KB3 AEELIRDGRYTDATSKYESVMKTEPSIAEYTVRSKERI-CH---CFSKDEKPVEAIRVCS ... ...: : : : .. .:. ..... .. :. :: .: .::. :. NP_001 GNKAFKEGNYKLAYELYTEALGIDPN----NIKTNAKLYCNRGTVNSKLRKLDDAIEDCT 210 220 230 240 250 260 340 350 360 370 380 390 pF1KB3 EVLQMEPDNVNALKDRAEAYLIEEMYDEAIQDYETAQEHNENDQQIREGLEKAQRLLKQS ...... ..: ::. :. :.:.::..::: . . .:. .. .. :..:: ::.: NP_001 NAVKLDDTYIKAYLRRAQCYMDTEQYEEAVRDYEKVYQ-TEKTKEHKQLLKNAQLELKKS 270 280 290 300 310 320 400 410 420 430 440 pF1KB3 QKRDYYKILGVKRNAKKQEIIKAYRKLALQWHPDNFQ--NEEEKKKAEKKFIDIAAAKEV ...:::::::: .::...:: ::::: ::. ::: . . : .:. :::: ... : . NP_001 KRKDYYKILGVDKNASEDEIKKAYRKRALMHHPDRHSGASAEVQKEEEKKFKEVGEAFTI 330 340 350 360 370 380 450 460 470 480 490 500 pF1KB3 LSDPEMRKKFDDGEDPLDAESQQGGGGNP---FHRSWNSWQGFNPFSSGGPFRFKFHFN ::::. . ..:.:.: :: :... : .: :. ... ::. : ..:: : :.: NP_001 LSDPKKKTRYDSGQD-LDEEGMNMGDFDPNNIFKAFFGGPGGFS-FEASGPGNFFFQFG 390 400 410 420 430 504 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 13:55:26 2016 done: Thu Nov 3 13:55:28 2016 Total Scan time: 7.930 Total Display time: 0.070 Function used was FASTA [36.3.4 Apr, 2011]