FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3767, 1093 aa 1>>>pF1KB3767 1093 - 1093 aa - 1093 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 16.6649+/-0.000613; mu= -33.8577+/- 0.038 mean_var=682.1994+/-138.396, 0's: 0 Z-trim(117.0): 292 B-trim: 0 in 0/60 Lambda= 0.049104 statistics sampled from 28360 (28611) to 28360 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.65), E-opt: 0.2 (0.335), width: 16 Scan time: 15.740 The best scores are: opt bits E(85289) NP_009045 (OMIM: 601126) TATA element modulatory f (1093) 6807 499.0 6.4e-140 XP_011532358 (OMIM: 601126) PREDICTED: TATA elemen (1096) 6791 497.8 1.4e-139 >>NP_009045 (OMIM: 601126) TATA element modulatory facto (1093 aa) initn: 6807 init1: 6807 opt: 6807 Z-score: 2633.0 bits: 499.0 E(85289): 6.4e-140 Smith-Waterman score: 6807; 100.0% identity (100.0% similar) in 1093 aa overlap (1-1093:1-1093) 10 20 30 40 50 60 pF1KB3 MSWFNASQLSSFAKQALSQAQKSIDRVLDIQEEEPSIWAETIPYGEPGISSPVSGGWDTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 MSWFNASQLSSFAKQALSQAQKSIDRVLDIQEEEPSIWAETIPYGEPGISSPVSGGWDTS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 TWGLKSNTEPQSPPIASPKAITKPVRRTVVDESENFFSAFLSPTDVQTIQKSPVVSKPPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 TWGLKSNTEPQSPPIASPKAITKPVRRTVVDESENFFSAFLSPTDVQTIQKSPVVSKPPA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 KSQRPEEEVKSSLHESLHIGQSRTPETTESQVKDSSLCVSGETLAAGTSSPKTEGKHEET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 KSQRPEEEVKSSLHESLHIGQSRTPETTESQVKDSSLCVSGETLAAGTSSPKTEGKHEET 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 VNKESDMKVPTVSLKVSESVIDVKTTMESISNTSTQSLTAETKDIALEPKEQKHEDRQSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 VNKESDMKVPTVSLKVSESVIDVKTTMESISNTSTQSLTAETKDIALEPKEQKHEDRQSN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 TPSPPVSTFSSGTSTTSDIEVLDHESVISESSASSRQETTDSKSSLHLMQTSFQLLSASA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 TPSPPVSTFSSGTSTTSDIEVLDHESVISESSASSRQETTDSKSSLHLMQTSFQLLSASA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 CPEYNRLDDFQKLTESCCSSDAFERIDSFSVQSLDSRSVSEINSDDELSGKGYALVPIIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 CPEYNRLDDFQKLTESCCSSDAFERIDSFSVQSLDSRSVSEINSDDELSGKGYALVPIIV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 NSSTPKSKTVESAEGKSEEVNETLVIPTEEAEMEESGRSATPVNCEQPDILVSSTPINEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 NSSTPKSKTVESAEGKSEEVNETLVIPTEEAEMEESGRSATPVNCEQPDILVSSTPINEG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 QTVLDKVAEQCEPAESQPEALSEKEDVCKTVEFLNEKLEKREAQLLSLSKEKALLEEAFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 QTVLDKVAEQCEPAESQPEALSEKEDVCKTVEFLNEKLEKREAQLLSLSKEKALLEEAFD 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 NLKDEMFRVKEESSSISSLKDEFTQRIAEAEKKVQLACKERDAAKKEIKNIKEELATRLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 NLKDEMFRVKEESSSISSLKDEFTQRIAEAEKKVQLACKERDAAKKEIKNIKEELATRLN 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 SSETADLLKEKDEQIRGLMEEGEKLSKQQLHNSNIIKKLRAKDKENENMVAKLNKKVKEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 SSETADLLKEKDEQIRGLMEEGEKLSKQQLHNSNIIKKLRAKDKENENMVAKLNKKVKEL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 EEELQHLKQVLDGKEEVEKQHRENIKKLNSMVERQEKDLGRLQVDMDELEEKNRSIQAAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 EEELQHLKQVLDGKEEVEKQHRENIKKLNSMVERQEKDLGRLQVDMDELEEKNRSIQAAL 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB3 DSAYKELTDLHKANAAKDSEAQEAALSREMKAKEELSAALEKAQEEARQQQETLAIQVGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 DSAYKELTDLHKANAAKDSEAQEAALSREMKAKEELSAALEKAQEEARQQQETLAIQVGD 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB3 LRLALQRTEQAAARKEDYLRHEIGELQQRLQEAENRNQELSQSVSSTTRPLLRQIENLQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 LRLALQRTEQAAARKEDYLRHEIGELQQRLQEAENRNQELSQSVSSTTRPLLRQIENLQA 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB3 TLGSQTSSWEKLEKNLSDRLGESQTLLAAAVERERAATEELLANKIQMSSMESQNSLLRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 TLGSQTSSWEKLEKNLSDRLGESQTLLAAAVERERAATEELLANKIQMSSMESQNSLLRQ 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB3 ENSRFQAQLESEKNRLCKLEDENNRYQVELENLKDEYVRTLEETRKEKTLLNSQLEMERM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 ENSRFQAQLESEKNRLCKLEDENNRYQVELENLKDEYVRTLEETRKEKTLLNSQLEMERM 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB3 KVEQERKKAIFTQETIKEKERKPFSVSSTPTMSRSSSISGVDMAGLQTSFLSQDESHDHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 KVEQERKKAIFTQETIKEKERKPFSVSSTPTMSRSSSISGVDMAGLQTSFLSQDESHDHS 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB3 FGPMPISANGSNLYDAVRMGAGSSIIENLQSQLKLREGEITHLQLEIGNLEKTRSIMAEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 FGPMPISANGSNLYDAVRMGAGSSIIENLQSQLKLREGEITHLQLEIGNLEKTRSIMAEE 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB3 LVKLTNQNDELEEKVKEIPKLRTQLRDLDQRYNTILQMYGEKAEEAEELRLDLEDVKNMY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_009 LVKLTNQNDELEEKVKEIPKLRTQLRDLDQRYNTILQMYGEKAEEAEELRLDLEDVKNMY 1030 1040 1050 1060 1070 1080 1090 pF1KB3 KTQIDELLRQSLS ::::::::::::: NP_009 KTQIDELLRQSLS 1090 >>XP_011532358 (OMIM: 601126) PREDICTED: TATA element mo (1096 aa) initn: 3952 init1: 3952 opt: 6791 Z-score: 2626.8 bits: 497.8 E(85289): 1.4e-139 Smith-Waterman score: 6791; 99.7% identity (99.7% similar) in 1096 aa overlap (1-1093:1-1096) 10 20 30 40 50 60 pF1KB3 MSWFNASQLSSFAKQALSQAQKSIDRVLDIQEEEPSIWAETIPYGEPGISSPVSGGWDTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MSWFNASQLSSFAKQALSQAQKSIDRVLDIQEEEPSIWAETIPYGEPGISSPVSGGWDTS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 TWGLKSNTEPQSPPIASPKAITKPVRRTVVDESENFFSAFLSPTDVQTIQKSPVVSKPPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TWGLKSNTEPQSPPIASPKAITKPVRRTVVDESENFFSAFLSPTDVQTIQKSPVVSKPPA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 KSQRPEEEVKSSLHESLHIGQSRTPETTESQVKDSSLCVSGETLAAGTSSPKTEGKHEET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KSQRPEEEVKSSLHESLHIGQSRTPETTESQVKDSSLCVSGETLAAGTSSPKTEGKHEET 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 VNKESDMKVPTVSLKVSESVIDVKTTMESISNTSTQSLTAETKDIALEPKEQKHEDRQSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VNKESDMKVPTVSLKVSESVIDVKTTMESISNTSTQSLTAETKDIALEPKEQKHEDRQSN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 TPSPPVSTFSSGTSTTSDIEVLDHESVISESSASSRQETTDSKSSLHLMQTSFQLLSASA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TPSPPVSTFSSGTSTTSDIEVLDHESVISESSASSRQETTDSKSSLHLMQTSFQLLSASA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 CPEYNRLDDFQKLTESCCSSDAFERIDSFSVQSLDSRSVSEINSDDELSGKGYALVPIIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CPEYNRLDDFQKLTESCCSSDAFERIDSFSVQSLDSRSVSEINSDDELSGKGYALVPIIV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 NSSTPKSKTVESAEGKSEEVNETLVIPTEEAEMEESGRSATPVNCEQPDILVSSTPINEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NSSTPKSKTVESAEGKSEEVNETLVIPTEEAEMEESGRSATPVNCEQPDILVSSTPINEG 370 380 390 400 410 420 430 440 450 460 470 pF1KB3 QTVLDKVAEQCEPAESQPEALSEKEDVCK---TVEFLNEKLEKREAQLLSLSKEKALLEE ::::::::::::::::::::::::::::: :::::::::::::::::::::::::::: XP_011 QTVLDKVAEQCEPAESQPEALSEKEDVCKVTLTVEFLNEKLEKREAQLLSLSKEKALLEE 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB3 AFDNLKDEMFRVKEESSSISSLKDEFTQRIAEAEKKVQLACKERDAAKKEIKNIKEELAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AFDNLKDEMFRVKEESSSISSLKDEFTQRIAEAEKKVQLACKERDAAKKEIKNIKEELAT 490 500 510 520 530 540 540 550 560 570 580 590 pF1KB3 RLNSSETADLLKEKDEQIRGLMEEGEKLSKQQLHNSNIIKKLRAKDKENENMVAKLNKKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RLNSSETADLLKEKDEQIRGLMEEGEKLSKQQLHNSNIIKKLRAKDKENENMVAKLNKKV 550 560 570 580 590 600 600 610 620 630 640 650 pF1KB3 KELEEELQHLKQVLDGKEEVEKQHRENIKKLNSMVERQEKDLGRLQVDMDELEEKNRSIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KELEEELQHLKQVLDGKEEVEKQHRENIKKLNSMVERQEKDLGRLQVDMDELEEKNRSIQ 610 620 630 640 650 660 660 670 680 690 700 710 pF1KB3 AALDSAYKELTDLHKANAAKDSEAQEAALSREMKAKEELSAALEKAQEEARQQQETLAIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AALDSAYKELTDLHKANAAKDSEAQEAALSREMKAKEELSAALEKAQEEARQQQETLAIQ 670 680 690 700 710 720 720 730 740 750 760 770 pF1KB3 VGDLRLALQRTEQAAARKEDYLRHEIGELQQRLQEAENRNQELSQSVSSTTRPLLRQIEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VGDLRLALQRTEQAAARKEDYLRHEIGELQQRLQEAENRNQELSQSVSSTTRPLLRQIEN 730 740 750 760 770 780 780 790 800 810 820 830 pF1KB3 LQATLGSQTSSWEKLEKNLSDRLGESQTLLAAAVERERAATEELLANKIQMSSMESQNSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQATLGSQTSSWEKLEKNLSDRLGESQTLLAAAVERERAATEELLANKIQMSSMESQNSL 790 800 810 820 830 840 840 850 860 870 880 890 pF1KB3 LRQENSRFQAQLESEKNRLCKLEDENNRYQVELENLKDEYVRTLEETRKEKTLLNSQLEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LRQENSRFQAQLESEKNRLCKLEDENNRYQVELENLKDEYVRTLEETRKEKTLLNSQLEM 850 860 870 880 890 900 900 910 920 930 940 950 pF1KB3 ERMKVEQERKKAIFTQETIKEKERKPFSVSSTPTMSRSSSISGVDMAGLQTSFLSQDESH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ERMKVEQERKKAIFTQETIKEKERKPFSVSSTPTMSRSSSISGVDMAGLQTSFLSQDESH 910 920 930 940 950 960 960 970 980 990 1000 1010 pF1KB3 DHSFGPMPISANGSNLYDAVRMGAGSSIIENLQSQLKLREGEITHLQLEIGNLEKTRSIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DHSFGPMPISANGSNLYDAVRMGAGSSIIENLQSQLKLREGEITHLQLEIGNLEKTRSIM 970 980 990 1000 1010 1020 1020 1030 1040 1050 1060 1070 pF1KB3 AEELVKLTNQNDELEEKVKEIPKLRTQLRDLDQRYNTILQMYGEKAEEAEELRLDLEDVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AEELVKLTNQNDELEEKVKEIPKLRTQLRDLDQRYNTILQMYGEKAEEAEELRLDLEDVK 1030 1040 1050 1060 1070 1080 1080 1090 pF1KB3 NMYKTQIDELLRQSLS :::::::::::::::: XP_011 NMYKTQIDELLRQSLS 1090 1093 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 13:56:53 2016 done: Thu Nov 3 13:56:55 2016 Total Scan time: 15.740 Total Display time: 0.060 Function used was FASTA [36.3.4 Apr, 2011]