FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3797, 474 aa
1>>>pF1KB3797 474 - 474 aa - 474 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.7419+/-0.000495; mu= 15.2399+/- 0.031
mean_var=72.5908+/-14.912, 0's: 0 Z-trim(107.7): 154 B-trim: 22 in 1/50
Lambda= 0.150534
statistics sampled from 15601 (15760) to 15601 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.536), E-opt: 0.2 (0.185), width: 16
Scan time: 5.880
The best scores are: opt bits E(85289)
NP_000804 (OMIM: 600232) gamma-aminobutyric acid r ( 474) 3136 691.1 1.7e-198
NP_000805 (OMIM: 137192,612269,617113) gamma-amino ( 473) 2552 564.3 2.6e-160
NP_000803 (OMIM: 137190,617153) gamma-aminobutyric ( 474) 2518 556.9 4.4e-158
NP_068712 (OMIM: 137192,612269,617113) gamma-amino ( 473) 2485 549.7 6.3e-156
NP_068711 (OMIM: 600232) gamma-aminobutyric acid r ( 512) 2382 527.4 3.6e-149
XP_011519730 (OMIM: 137192,612269,617113) PREDICTE ( 414) 2147 476.3 7e-134
NP_001178250 (OMIM: 137192,612269,617113) gamma-am ( 402) 2146 476.1 7.9e-134
NP_001265560 (OMIM: 137192,612269,617113) gamma-am ( 388) 2115 469.3 8.1e-132
NP_001178249 (OMIM: 137192,612269,617113) gamma-am ( 388) 2115 469.3 8.1e-132
XP_016863474 (OMIM: 137190,617153) PREDICTED: gamm ( 257) 1245 280.3 4.3e-75
XP_011529486 (OMIM: 300349) PREDICTED: gamma-amino ( 406) 1227 276.5 9.6e-74
NP_061028 (OMIM: 300349) gamma-aminobutyric acid r ( 632) 1227 276.6 1.4e-73
NP_000806 (OMIM: 137163,613060) gamma-aminobutyric ( 452) 1090 246.8 9.5e-65
XP_011539496 (OMIM: 137163,613060) PREDICTED: gamm ( 465) 1090 246.8 9.8e-65
XP_016856425 (OMIM: 137163,613060) PREDICTED: gamm ( 687) 1090 246.8 1.4e-64
NP_001243632 (OMIM: 137161) gamma-aminobutyric aci ( 462) 1031 234.0 7e-61
NP_002033 (OMIM: 137161) gamma-aminobutyric acid r ( 479) 1031 234.0 7.2e-61
XP_016866178 (OMIM: 137161) PREDICTED: gamma-amino ( 392) 1021 231.8 2.7e-60
NP_001243633 (OMIM: 137161) gamma-aminobutyric aci ( 392) 1021 231.8 2.7e-60
NP_001254511 (OMIM: 137161) gamma-aminobutyric aci ( 392) 1021 231.8 2.7e-60
NP_002034 (OMIM: 137162) gamma-aminobutyric acid r ( 465) 1003 227.9 4.8e-59
NP_055026 (OMIM: 602729) gamma-aminobutyric acid r ( 440) 998 226.8 9.6e-59
XP_011534015 (OMIM: 137162) PREDICTED: gamma-amino ( 421) 960 218.5 2.8e-56
XP_006724550 (OMIM: 305990) PREDICTED: glycine rec ( 436) 948 215.9 1.8e-55
XP_011543798 (OMIM: 305990) PREDICTED: glycine rec ( 436) 948 215.9 1.8e-55
XP_011543797 (OMIM: 305990) PREDICTED: glycine rec ( 436) 948 215.9 1.8e-55
NP_001112357 (OMIM: 305990) glycine receptor subun ( 452) 947 215.7 2.1e-55
NP_002054 (OMIM: 305990) glycine receptor subunit ( 452) 947 215.7 2.1e-55
NP_001112358 (OMIM: 305990) glycine receptor subun ( 452) 945 215.3 2.9e-55
XP_016884916 (OMIM: 305990) PREDICTED: glycine rec ( 452) 945 215.3 2.9e-55
NP_000162 (OMIM: 138491,149400) glycine receptor s ( 449) 943 214.8 3.9e-55
XP_016864838 (OMIM: 138491,149400) PREDICTED: glyc ( 465) 942 214.6 4.6e-55
NP_001036008 (OMIM: 600421) glycine receptor subun ( 449) 940 214.2 6.1e-55
NP_001139512 (OMIM: 138491,149400) glycine recepto ( 457) 940 214.2 6.2e-55
NP_006520 (OMIM: 600421) glycine receptor subunit ( 464) 940 214.2 6.2e-55
NP_000807 (OMIM: 137164,607681,611277) gamma-amino ( 467) 933 212.7 1.8e-54
NP_944494 (OMIM: 137164,607681,611277) gamma-amino ( 475) 933 212.7 1.8e-54
XP_016864119 (OMIM: 600421) PREDICTED: glycine rec ( 424) 929 211.8 3e-54
NP_775807 (OMIM: 137166) gamma-aminobutyric acid r ( 465) 896 204.6 4.7e-52
XP_011511977 (OMIM: 103780,137140) PREDICTED: gamm ( 511) 896 204.7 5.1e-52
NP_001317619 (OMIM: 103780,137140) gamma-aminobuty ( 511) 896 204.7 5.1e-52
NP_150092 (OMIM: 600233) gamma-aminobutyric acid r ( 467) 895 204.4 5.5e-52
XP_011519732 (OMIM: 600233) PREDICTED: gamma-amino ( 473) 895 204.4 5.5e-52
NP_000815 (OMIM: 138492,614619) glycine receptor s ( 497) 894 204.2 6.7e-52
NP_001159532 (OMIM: 138492,614619) glycine recepto ( 497) 894 204.2 6.7e-52
NP_001107647 (OMIM: 103780,137140) gamma-aminobuty ( 451) 886 202.5 2.1e-51
NP_000798 (OMIM: 103780,137140) gamma-aminobutyric ( 451) 886 202.5 2.1e-51
XP_016863472 (OMIM: 103780,137140) PREDICTED: gamm ( 451) 886 202.5 2.1e-51
XP_016863471 (OMIM: 103780,137140) PREDICTED: gamm ( 451) 886 202.5 2.1e-51
XP_016863475 (OMIM: 137190,617153) PREDICTED: gamm ( 247) 881 201.3 2.6e-51
>>NP_000804 (OMIM: 600232) gamma-aminobutyric acid recep (474 aa)
initn: 3136 init1: 3136 opt: 3136 Z-score: 3684.5 bits: 691.1 E(85289): 1.7e-198
Smith-Waterman score: 3136; 100.0% identity (100.0% similar) in 474 aa overlap (1-474:1-474)
10 20 30 40 50 60
pF1KB3 MWRVRKRGYFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MWRVRKRGYFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 AVGMNIDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 AVGMNIDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 YFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 YFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIES
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 YGYTTDDIEFYWRGDDNAVTGVTKIELPQFSIVDYKLITKKVVFSTGSYPRLSLSFKLKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 YGYTTDDIEFYWRGDDNAVTGVTKIELPQFSIVDYKLITKKVVFSTGSYPRLSLSFKLKR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 NIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 NIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 YVKAIDMYLMGCFVFVFMALLEYALVNYIFFGRGPQRQKKAAEKAASANNEKMRLDVNKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 YVKAIDMYLMGCFVFVFMALLEYALVNYIFFGRGPQRQKKAAEKAASANNEKMRLDVNKM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 DPHENILLSTLEIKNEMATSEAVMGLGDPRSTMLAYDASSIQYRKAGLPRHSFGRNALER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 DPHENILLSTLEIKNEMATSEAVMGLGDPRSTMLAYDASSIQYRKAGLPRHSFGRNALER
370 380 390 400 410 420
430 440 450 460 470
pF1KB3 HVAQKKSRLRRRASQLKITIPDLTDVNAIDRWSRIFFPVVFSFFNIVYWLYYVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 HVAQKKSRLRRRASQLKITIPDLTDVNAIDRWSRIFFPVVFSFFNIVYWLYYVN
430 440 450 460 470
>>NP_000805 (OMIM: 137192,612269,617113) gamma-aminobuty (473 aa)
initn: 2120 init1: 2120 opt: 2552 Z-score: 2999.1 bits: 564.3 E(85289): 2.6e-160
Smith-Waterman score: 2552; 79.8% identity (92.4% similar) in 475 aa overlap (1-474:1-473)
10 20 30 40 50
pF1KB3 MWRVRKRGYFGIWSFPLIIAAVC-AQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPP
:: . :::.: :...:.:: :::::::.:::.::::::.:::::::::::::::::
NP_000 MWGLAGGRLFGIFSAPVLVAVVCCAQSVNDPGNMSFVKETVDKLLKGYDIRLRPDFGGPP
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB3 VAVGMNIDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPD
: :::::::::::::::::::::::::::: ::::::.:. :::::::::::::::::::
NP_000 VCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLNLTLDNRVADQLWVPD
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB3 TYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIE
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB3 SYGYTTDDIEFYWRGDDNAVTGVTKIELPQFSIVDYKLITKKVVFSTGSYPRLSLSFKLK
::::::::::::::: :.::::: .:::::::::...:....:::.::.::::::::.::
NP_000 SYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEHRLVSRNVVFATGAYPRLSLSFRLK
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB3 RNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKI
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB3 PYVKAIDMYLMGCFVFVFMALLEYALVNYIFFGRGPQRQKKAAEKAASANNEKMRLDVNK
::::::::::::::::::.::::::.::::::::::::::: :::.:.:.:.. . . :.
NP_000 PYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQRQKKLAEKTAKAKNDRSKSESNR
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB3 MDPHENILLSTLEIKNEMATSEAVMGLGDPRSTMLAYDASSIQYRKAGLPRHSFGRNALE
.: : ::::..::..::: .:. :.:: :.. ...: :.::::: ..::.. :: .
NP_000 VDAHGNILLTSLEVHNEM--NEVSGGIGDTRNSAISFDNSGIQYRKQSMPREGHGRFLGD
370 380 390 400 410
420 430 440 450 460 470
pF1KB3 RHVAQKKSRLRRRASQLKITIPDLTDVNAIDRWSRIFFPVVFSFFNIVYWLYYVN
: . .::..::::.::::: :::::::::::::::: :: .::.::.::::::::
NP_000 RSLPHKKTHLRRRSSQLKIKIPDLTDVNAIDRWSRIVFPFTFSLFNLVYWLYYVN
420 430 440 450 460 470
>>NP_000803 (OMIM: 137190,617153) gamma-aminobutyric aci (474 aa)
initn: 2446 init1: 2152 opt: 2518 Z-score: 2959.1 bits: 556.9 E(85289): 4.4e-158
Smith-Waterman score: 2518; 78.8% identity (92.2% similar) in 477 aa overlap (1-474:1-474)
10 20 30 40 50
pF1KB3 MWRVRKRGYFGIWSFPLIIAAVC-AQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPP
:: :..: .:. :::..:. :: :.:.:.::::: ::::::::::::::::::::::::
NP_000 MWTVQNRESLGLLSFPVMITMVCCAHSTNEPSNMSYVKETVDRLLKGYDIRLRPDFGGPP
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB3 VAVGMNIDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPD
: ::: ::.:::::::::::::::::::::.:.::::::. :::::::::::::::::::
NP_000 VDVGMRIDVASIDMVSEVNMDYTLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLWVPD
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB3 TYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIE
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB3 SYGYTTDDIEFYWRGDDNAVTGVTKIELPQFSIVDYKLITKKVVFSTGSYPRLSLSFKLK
::::::::::::: : ..:::::.:::::::::::::...::: :.::.::::::::.::
NP_000 SYGYTTDDIEFYWNGGEGAVTGVNKIELPQFSIVDYKMVSKKVEFTTGAYPRLSLSFRLK
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB3 RNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKI
:::::::::::::: ::::::::::::::::::::::::::::::::::.::::::::::
NP_000 RNIGYFILQTYMPSTLITILSWVSFWINYDASAARVALGITTVLTMTTISTHLRETLPKI
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB3 PYVKAIDMYLMGCFVFVFMALLEYALVNYIFFGRGPQRQKKAAEKAASANNEKMRLDVNK
:::::::.::::::::::.::::::.:::::::.::: ::.: : .. ::: .:..::
NP_000 PYVKAIDIYLMGCFVFVFLALLEYAFVNYIFFGKGPQ--KKGASKQDQSANEKNKLEMNK
310 320 330 340 350
360 370 380 390 400 410
pF1KB3 M--DPHENILLSTLEIKNEMATSEAVMGLGDPRSTMLAYDASSIQYRKAGLPRHSFGRNA
. : : :::::::::.:: . ::.. ...::..:: .::..:::::: :...:: :
NP_000 VQVDAHGNILLSTLEIRNETSGSEVLTSVSDPKATMYSYDSASIQYRKPLSSREAYGR-A
360 370 380 390 400 410
420 430 440 450 460 470
pF1KB3 LERHVAQKKSRLRRRASQLKITIPDLTDVNAIDRWSRIFFPVVFSFFNIVYWLYYVN
:.:: . .:.:.::::::::. ::::::::.::.:::.:::..::.::.:::::::.
NP_000 LDRHGVPSKGRIRRRASQLKVKIPDLTDVNSIDKWSRMFFPITFSLFNVVYWLYYVH
420 430 440 450 460 470
>>NP_068712 (OMIM: 137192,612269,617113) gamma-aminobuty (473 aa)
initn: 2089 init1: 2089 opt: 2485 Z-score: 2920.4 bits: 549.7 E(85289): 6.3e-156
Smith-Waterman score: 2485; 80.0% identity (92.2% similar) in 464 aa overlap (12-474:12-473)
10 20 30 40 50
pF1KB3 MWRVRKRGYFGIW-SFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPP
:: :. : . .:::::.:::.::::::.:::::::::::::::::
NP_068 MCSGLLELLLPIWLSWTLGTRGSEPRSVNDPGNMSFVKETVDKLLKGYDIRLRPDFGGPP
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB3 VAVGMNIDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPD
: :::::::::::::::::::::::::::: ::::::.:. :::::::::::::::::::
NP_068 VCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLNLTLDNRVADQLWVPD
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB3 TYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 TYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIE
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB3 SYGYTTDDIEFYWRGDDNAVTGVTKIELPQFSIVDYKLITKKVVFSTGSYPRLSLSFKLK
::::::::::::::: :.::::: .:::::::::...:....:::.::.::::::::.::
NP_068 SYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEHRLVSRNVVFATGAYPRLSLSFRLK
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB3 RNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 RNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKI
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB3 PYVKAIDMYLMGCFVFVFMALLEYALVNYIFFGRGPQRQKKAAEKAASANNEKMRLDVNK
::::::::::::::::::.::::::.::::::::::::::: :::.:.:.:.. . . :.
NP_068 PYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQRQKKLAEKTAKAKNDRSKSESNR
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB3 MDPHENILLSTLEIKNEMATSEAVMGLGDPRSTMLAYDASSIQYRKAGLPRHSFGRNALE
.: : ::::..::..::: .:. :.:: :.. ...: :.::::: ..::.. :: .
NP_068 VDAHGNILLTSLEVHNEM--NEVSGGIGDTRNSAISFDNSGIQYRKQSMPREGHGRFLGD
370 380 390 400 410
420 430 440 450 460 470
pF1KB3 RHVAQKKSRLRRRASQLKITIPDLTDVNAIDRWSRIFFPVVFSFFNIVYWLYYVN
: . .::..::::.::::: :::::::::::::::: :: .::.::.::::::::
NP_068 RSLPHKKTHLRRRSSQLKIKIPDLTDVNAIDRWSRIVFPFTFSLFNLVYWLYYVN
420 430 440 450 460 470
>>NP_068711 (OMIM: 600232) gamma-aminobutyric acid recep (512 aa)
initn: 3124 init1: 2382 opt: 2382 Z-score: 2799.0 bits: 527.4 E(85289): 3.6e-149
Smith-Waterman score: 3002; 92.5% identity (92.5% similar) in 506 aa overlap (1-468:1-506)
10 20 30 40 50 60
pF1KB3 MWRVRKRGYFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 MWRVRKRGYFGIWSFPLIIAAVCAQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 AVGMNIDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 AVGMNIDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 YFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 YFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIES
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 YGYTTDDIEFYWRGDDNAVTGVTKIELPQFSIVDYKLITKKVVFSTGSYPRLSLSFKLKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 YGYTTDDIEFYWRGDDNAVTGVTKIELPQFSIVDYKLITKKVVFSTGSYPRLSLSFKLKR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 NIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 NIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIP
250 260 270 280 290 300
310 320 330 340 350
pF1KB3 YVKAIDMYLMGCFVFVFMALLEYALVNYIFFGRGPQRQKKAAEKAASANNEKMRLDVNK-
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 YVKAIDMYLMGCFVFVFMALLEYALVNYIFFGRGPQRQKKAAEKAASANNEKMRLDVNKI
310 320 330 340 350 360
360 370 380
pF1KB3 -------------------------------------MDPHENILLSTLEIKNEMATSEA
:::::::::::::::::::::::
NP_068 FYKDIKQNGTQYRSLWDPTGNLSPTRRTTNYDFSLYTMDPHENILLSTLEIKNEMATSEA
370 380 390 400 410 420
390 400 410 420 430 440
pF1KB3 VMGLGDPRSTMLAYDASSIQYRKAGLPRHSFGRNALERHVAQKKSRLRRRASQLKITIPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 VMGLGDPRSTMLAYDASSIQYRKAGLPRHSFGRNALERHVAQKKSRLRRRASQLKITIPD
430 440 450 460 470 480
450 460 470
pF1KB3 LTDVNAIDRWSRIFFPVVFSFFNIVYWLYYVN
::::::::::::::::::::::::::
NP_068 LTDVNAIDRWSRIFFPVVFSFFNIVYWLYYVN
490 500 510
>>XP_011519730 (OMIM: 137192,612269,617113) PREDICTED: g (414 aa)
initn: 1756 init1: 1756 opt: 2147 Z-score: 2524.6 bits: 476.3 E(85289): 7e-134
Smith-Waterman score: 2147; 79.6% identity (92.7% similar) in 398 aa overlap (77-474:19-414)
50 60 70 80 90 100
pF1KB3 YDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLT
. :::::::::: ::::::.:. ::::::
XP_011 MQIPSLCDCALLFGSCHIIAKDYTLTMYFQQYWRDKRLAYSGIPLNLT
10 20 30 40
110 120 130 140 150 160
pF1KB3 LDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRR
50 60 70 80 90 100
170 180 190 200 210 220
pF1KB3 YPLDEQNCTLEIESYGYTTDDIEFYWRGDDNAVTGVTKIELPQFSIVDYKLITKKVVFST
:::::::::::::::::::::::::::: :.::::: .:::::::::...:....:::.:
XP_011 YPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEHRLVSRNVVFAT
110 120 130 140 150 160
230 240 250 260 270 280
pF1KB3 GSYPRLSLSFKLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMT
:.::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMT
170 180 190 200 210 220
290 300 310 320 330 340
pF1KB3 TINTHLRETLPKIPYVKAIDMYLMGCFVFVFMALLEYALVNYIFFGRGPQRQKKAAEKAA
:::::::::::::::::::::::::::::::.::::::.::::::::::::::: :::.:
XP_011 TINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQRQKKLAEKTA
230 240 250 260 270 280
350 360 370 380 390 400
pF1KB3 SANNEKMRLDVNKMDPHENILLSTLEIKNEMATSEAVMGLGDPRSTMLAYDASSIQYRKA
.:.:.. . . :..: : ::::..::..::: .:. :.:: :.. ...: :.:::::
XP_011 KAKNDRSKSESNRVDAHGNILLTSLEVHNEM--NEVSGGIGDTRNSAISFDNSGIQYRKQ
290 300 310 320 330 340
410 420 430 440 450 460
pF1KB3 GLPRHSFGRNALERHVAQKKSRLRRRASQLKITIPDLTDVNAIDRWSRIFFPVVFSFFNI
..::.. :: .: . .::..::::.::::: :::::::::::::::: :: .::.::.
XP_011 SMPREGHGRFLGDRSLPHKKTHLRRRSSQLKIKIPDLTDVNAIDRWSRIVFPFTFSLFNL
350 360 370 380 390 400
470
pF1KB3 VYWLYYVN
::::::::
XP_011 VYWLYYVN
410
>>NP_001178250 (OMIM: 137192,612269,617113) gamma-aminob (402 aa)
initn: 1755 init1: 1755 opt: 2146 Z-score: 2523.6 bits: 476.1 E(85289): 7.9e-134
Smith-Waterman score: 2146; 80.3% identity (93.2% similar) in 395 aa overlap (80-474:10-402)
50 60 70 80 90 100
pF1KB3 RLRPDFGGPPVAVGMNIDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDN
:::::::::: ::::::.:. :::::::::
NP_001 MWATYQTEEDYTLTMYFQQYWRDKRLAYSGIPLNLTLDN
10 20 30
110 120 130 140 150 160
pF1KB3 RVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPL
40 50 60 70 80 90
170 180 190 200 210 220
pF1KB3 DEQNCTLEIESYGYTTDDIEFYWRGDDNAVTGVTKIELPQFSIVDYKLITKKVVFSTGSY
::::::::::::::::::::::::: :.::::: .:::::::::...:....:::.::.:
NP_001 DEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEHRLVSRNVVFATGAY
100 110 120 130 140 150
230 240 250 260 270 280
pF1KB3 PRLSLSFKLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTIN
:::::::.::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTIN
160 170 180 190 200 210
290 300 310 320 330 340
pF1KB3 THLRETLPKIPYVKAIDMYLMGCFVFVFMALLEYALVNYIFFGRGPQRQKKAAEKAASAN
::::::::::::::::::::::::::::.::::::.::::::::::::::: :::.:.:.
NP_001 THLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQRQKKLAEKTAKAK
220 230 240 250 260 270
350 360 370 380 390 400
pF1KB3 NEKMRLDVNKMDPHENILLSTLEIKNEMATSEAVMGLGDPRSTMLAYDASSIQYRKAGLP
:.. . . :..: : ::::..::..::: .:. :.:: :.. ...: :.::::: ..:
NP_001 NDRSKSESNRVDAHGNILLTSLEVHNEM--NEVSGGIGDTRNSAISFDNSGIQYRKQSMP
280 290 300 310 320 330
410 420 430 440 450 460
pF1KB3 RHSFGRNALERHVAQKKSRLRRRASQLKITIPDLTDVNAIDRWSRIFFPVVFSFFNIVYW
:.. :: .: . .::..::::.::::: :::::::::::::::: :: .::.::.:::
NP_001 REGHGRFLGDRSLPHKKTHLRRRSSQLKIKIPDLTDVNAIDRWSRIVFPFTFSLFNLVYW
340 350 360 370 380 390
470
pF1KB3 LYYVN
:::::
NP_001 LYYVN
400
>>NP_001265560 (OMIM: 137192,612269,617113) gamma-aminob (388 aa)
initn: 1724 init1: 1724 opt: 2115 Z-score: 2487.5 bits: 469.3 E(85289): 8.1e-132
Smith-Waterman score: 2115; 80.0% identity (93.1% similar) in 390 aa overlap (85-474:1-388)
60 70 80 90 100 110
pF1KB3 FGGPPVAVGMNIDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQ
::::: ::::::.:. ::::::::::::::
NP_001 MYFQQYWRDKRLAYSGIPLNLTLDNRVADQ
10 20 30
120 130 140 150 160 170
pF1KB3 LWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNC
40 50 60 70 80 90
180 190 200 210 220 230
pF1KB3 TLEIESYGYTTDDIEFYWRGDDNAVTGVTKIELPQFSIVDYKLITKKVVFSTGSYPRLSL
:::::::::::::::::::: :.::::: .:::::::::...:....:::.::.::::::
NP_001 TLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEHRLVSRNVVFATGAYPRLSL
100 110 120 130 140 150
240 250 260 270 280 290
pF1KB3 SFKLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRE
::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRE
160 170 180 190 200 210
300 310 320 330 340 350
pF1KB3 TLPKIPYVKAIDMYLMGCFVFVFMALLEYALVNYIFFGRGPQRQKKAAEKAASANNEKMR
:::::::::::::::::::::::.::::::.::::::::::::::: :::.:.:.:.. .
NP_001 TLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQRQKKLAEKTAKAKNDRSK
220 230 240 250 260 270
360 370 380 390 400 410
pF1KB3 LDVNKMDPHENILLSTLEIKNEMATSEAVMGLGDPRSTMLAYDASSIQYRKAGLPRHSFG
. :..: : ::::..::..::: .:. :.:: :.. ...: :.::::: ..::.. :
NP_001 SESNRVDAHGNILLTSLEVHNEM--NEVSGGIGDTRNSAISFDNSGIQYRKQSMPREGHG
280 290 300 310 320
420 430 440 450 460 470
pF1KB3 RNALERHVAQKKSRLRRRASQLKITIPDLTDVNAIDRWSRIFFPVVFSFFNIVYWLYYVN
: .: . .::..::::.::::: :::::::::::::::: :: .::.::.::::::::
NP_001 RFLGDRSLPHKKTHLRRRSSQLKIKIPDLTDVNAIDRWSRIVFPFTFSLFNLVYWLYYVN
330 340 350 360 370 380
>>NP_001178249 (OMIM: 137192,612269,617113) gamma-aminob (388 aa)
initn: 1724 init1: 1724 opt: 2115 Z-score: 2487.5 bits: 469.3 E(85289): 8.1e-132
Smith-Waterman score: 2115; 80.0% identity (93.1% similar) in 390 aa overlap (85-474:1-388)
60 70 80 90 100 110
pF1KB3 FGGPPVAVGMNIDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQ
::::: ::::::.:. ::::::::::::::
NP_001 MYFQQYWRDKRLAYSGIPLNLTLDNRVADQ
10 20 30
120 130 140 150 160 170
pF1KB3 LWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNC
40 50 60 70 80 90
180 190 200 210 220 230
pF1KB3 TLEIESYGYTTDDIEFYWRGDDNAVTGVTKIELPQFSIVDYKLITKKVVFSTGSYPRLSL
:::::::::::::::::::: :.::::: .:::::::::...:....:::.::.::::::
NP_001 TLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEHRLVSRNVVFATGAYPRLSL
100 110 120 130 140 150
240 250 260 270 280 290
pF1KB3 SFKLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRE
::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRE
160 170 180 190 200 210
300 310 320 330 340 350
pF1KB3 TLPKIPYVKAIDMYLMGCFVFVFMALLEYALVNYIFFGRGPQRQKKAAEKAASANNEKMR
:::::::::::::::::::::::.::::::.::::::::::::::: :::.:.:.:.. .
NP_001 TLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQRQKKLAEKTAKAKNDRSK
220 230 240 250 260 270
360 370 380 390 400 410
pF1KB3 LDVNKMDPHENILLSTLEIKNEMATSEAVMGLGDPRSTMLAYDASSIQYRKAGLPRHSFG
. :..: : ::::..::..::: .:. :.:: :.. ...: :.::::: ..::.. :
NP_001 SESNRVDAHGNILLTSLEVHNEM--NEVSGGIGDTRNSAISFDNSGIQYRKQSMPREGHG
280 290 300 310 320
420 430 440 450 460 470
pF1KB3 RNALERHVAQKKSRLRRRASQLKITIPDLTDVNAIDRWSRIFFPVVFSFFNIVYWLYYVN
: .: . .::..::::.::::: :::::::::::::::: :: .::.::.::::::::
NP_001 RFLGDRSLPHKKTHLRRRSSQLKIKIPDLTDVNAIDRWSRIVFPFTFSLFNLVYWLYYVN
330 340 350 360 370 380
>>XP_016863474 (OMIM: 137190,617153) PREDICTED: gamma-am (257 aa)
initn: 1229 init1: 935 opt: 1245 Z-score: 1469.1 bits: 280.3 E(85289): 4.3e-75
Smith-Waterman score: 1245; 72.3% identity (90.4% similar) in 260 aa overlap (217-474:1-257)
190 200 210 220 230 240
pF1KB3 DIEFYWRGDDNAVTGVTKIELPQFSIVDYKLITKKVVFSTGSYPRLSLSFKLKRNIGYFI
...::: :.::.::::::::.:::::::::
XP_016 MVSKKVEFTTGAYPRLSLSFRLKRNIGYFI
10 20 30
250 260 270 280 290 300
pF1KB3 LQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAID
::::::: ::::::::::::::::::::::::::::::::::.:::::::::::::::::
XP_016 LQTYMPSTLITILSWVSFWINYDASAARVALGITTVLTMTTISTHLRETLPKIPYVKAID
40 50 60 70 80 90
310 320 330 340 350 360
pF1KB3 MYLMGCFVFVFMALLEYALVNYIFFGRGPQRQKKAAEKAASANNEKMRLDVNKM--DPHE
.::::::::::.::::::.:::::::.::: ::.: : .. ::: .:..::. : :
XP_016 IYLMGCFVFVFLALLEYAFVNYIFFGKGPQ--KKGASKQDQSANEKNKLEMNKVQVDAHG
100 110 120 130 140
370 380 390 400 410 420
pF1KB3 NILLSTLEIKNEMATSEAVMGLGDPRSTMLAYDASSIQYRKAGLPRHSFGRNALERHVAQ
:::::::::.:: . ::.. ...::..:: .::..:::::: :...:: ::.:: .
XP_016 NILLSTLEIRNETSGSEVLTSVSDPKATMYSYDSASIQYRKPLSSREAYGR-ALDRHGVP
150 160 170 180 190 200
430 440 450 460 470
pF1KB3 KKSRLRRRASQLKITIPDLTDVNAIDRWSRIFFPVVFSFFNIVYWLYYVN
.:.:.::::::::. ::::::::.::.:::.:::..::.::.:::::::.
XP_016 SKGRIRRRASQLKVKIPDLTDVNSIDKWSRMFFPITFSLFNVVYWLYYVH
210 220 230 240 250
474 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 13:58:21 2016 done: Thu Nov 3 13:58:22 2016
Total Scan time: 5.880 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]