FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3810, 500 aa 1>>>pF1KB3810 500 - 500 aa - 500 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.1266+/-0.0005; mu= 6.6643+/- 0.031 mean_var=402.8092+/-91.095, 0's: 0 Z-trim(118.0): 1475 B-trim: 106 in 1/55 Lambda= 0.063903 statistics sampled from 28545 (30481) to 28545 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.713), E-opt: 0.2 (0.357), width: 16 Scan time: 8.500 The best scores are: opt bits E(85289) NP_002646 (OMIM: 181030,603026) zinc finger protei ( 500) 3399 328.3 3.1e-89 NP_001108106 (OMIM: 181030,603026) zinc finger pro ( 500) 3399 328.3 3.1e-89 XP_016869065 (OMIM: 181030,603026) PREDICTED: zinc ( 500) 3399 328.3 3.1e-89 XP_016869066 (OMIM: 181030,603026) PREDICTED: zinc ( 418) 2831 275.9 1.6e-73 XP_011515846 (OMIM: 181030,603026) PREDICTED: zinc ( 418) 2831 275.9 1.6e-73 NP_001108107 (OMIM: 181030,603026) zinc finger pro ( 418) 2831 275.9 1.6e-73 XP_011527166 (OMIM: 604866) PREDICTED: zinc finger ( 496) 1458 149.4 2.3e-35 XP_005260493 (OMIM: 604866) PREDICTED: zinc finger ( 496) 1458 149.4 2.3e-35 NP_002648 (OMIM: 604866) zinc finger protein PLAGL ( 496) 1458 149.4 2.3e-35 XP_011527165 (OMIM: 604866) PREDICTED: zinc finger ( 496) 1458 149.4 2.3e-35 NP_001304088 (OMIM: 601410,603044) zinc finger pro ( 463) 1293 134.1 8.3e-31 NP_001275975 (OMIM: 601410,603044) zinc finger pro ( 463) 1293 134.1 8.3e-31 NP_001275977 (OMIM: 601410,603044) zinc finger pro ( 463) 1293 134.1 8.3e-31 NP_001304085 (OMIM: 601410,603044) zinc finger pro ( 463) 1293 134.1 8.3e-31 NP_001074422 (OMIM: 601410,603044) zinc finger pro ( 463) 1293 134.1 8.3e-31 NP_001304091 (OMIM: 601410,603044) zinc finger pro ( 463) 1293 134.1 8.3e-31 NP_001275974 (OMIM: 601410,603044) zinc finger pro ( 463) 1293 134.1 8.3e-31 NP_001275978 (OMIM: 601410,603044) zinc finger pro ( 463) 1293 134.1 8.3e-31 NP_001074420 (OMIM: 601410,603044) zinc finger pro ( 463) 1293 134.1 8.3e-31 NP_001304086 (OMIM: 601410,603044) zinc finger pro ( 463) 1293 134.1 8.3e-31 NP_006709 (OMIM: 601410,603044) zinc finger protei ( 463) 1293 134.1 8.3e-31 NP_001074423 (OMIM: 601410,603044) zinc finger pro ( 463) 1293 134.1 8.3e-31 NP_001275972 (OMIM: 601410,603044) zinc finger pro ( 463) 1293 134.1 8.3e-31 NP_001074421 (OMIM: 601410,603044) zinc finger pro ( 463) 1293 134.1 8.3e-31 NP_001304090 (OMIM: 601410,603044) zinc finger pro ( 463) 1293 134.1 8.3e-31 NP_001275971 (OMIM: 601410,603044) zinc finger pro ( 463) 1293 134.1 8.3e-31 NP_001275976 (OMIM: 601410,603044) zinc finger pro ( 463) 1293 134.1 8.3e-31 NP_001275973 (OMIM: 601410,603044) zinc finger pro ( 463) 1293 134.1 8.3e-31 NP_001275970 (OMIM: 601410,603044) zinc finger pro ( 411) 1029 109.7 1.7e-23 NP_001275969 (OMIM: 601410,603044) zinc finger pro ( 411) 1029 109.7 1.7e-23 NP_001074425 (OMIM: 601410,603044) zinc finger pro ( 411) 1029 109.7 1.7e-23 NP_001275966 (OMIM: 601410,603044) zinc finger pro ( 411) 1029 109.7 1.7e-23 NP_001304089 (OMIM: 601410,603044) zinc finger pro ( 411) 1029 109.7 1.7e-23 NP_001074424 (OMIM: 601410,603044) zinc finger pro ( 411) 1029 109.7 1.7e-23 NP_001275967 (OMIM: 601410,603044) zinc finger pro ( 411) 1029 109.7 1.7e-23 NP_001275968 (OMIM: 601410,603044) zinc finger pro ( 411) 1029 109.7 1.7e-23 NP_001304087 (OMIM: 601410,603044) zinc finger pro ( 411) 1029 109.7 1.7e-23 NP_001255984 (OMIM: 607022) transcriptional repres ( 299) 497 60.4 8.1e-09 NP_001255983 (OMIM: 607022) transcriptional repres ( 403) 497 60.6 9.5e-09 NP_001255979 (OMIM: 607022) transcriptional repres ( 422) 497 60.7 9.7e-09 NP_001255978 (OMIM: 607022) transcriptional repres ( 460) 497 60.7 1e-08 NP_001255976 (OMIM: 607022) transcriptional repres ( 573) 497 60.9 1.1e-08 NP_001255974 (OMIM: 607022) transcriptional repres ( 627) 497 61.0 1.2e-08 NP_001255971 (OMIM: 607022) transcriptional repres ( 662) 497 61.0 1.2e-08 NP_001255970 (OMIM: 607022) transcriptional repres ( 663) 497 61.0 1.2e-08 NP_001255969 (OMIM: 607022) transcriptional repres ( 663) 497 61.0 1.2e-08 NP_542185 (OMIM: 607022) transcriptional repressor ( 663) 497 61.0 1.2e-08 NP_001255973 (OMIM: 607022) transcriptional repres ( 665) 497 61.0 1.2e-08 NP_001255972 (OMIM: 607022) transcriptional repres ( 700) 497 61.0 1.3e-08 NP_001265576 (OMIM: 165270) zinc finger and BTB do ( 688) 483 59.7 3.1e-08 >>NP_002646 (OMIM: 181030,603026) zinc finger protein PL (500 aa) initn: 3399 init1: 3399 opt: 3399 Z-score: 1723.1 bits: 328.3 E(85289): 3.1e-89 Smith-Waterman score: 3399; 99.8% identity (100.0% similar) in 500 aa overlap (1-500:1-500) 10 20 30 40 50 60 pF1KB3 MATVIPGDLSEVRDTQKVPSGKRKRGETKPRKNFPCQLCDKAFNSVEKLKVHSYSHTGER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MATVIPGDLSEVRDTQKVPSGKRKRGETKPRKNFPCQLCDKAFNSVEKLKVHSYSHTGER 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 PYKCIQQDCTKAFVSKYKLQRHMATHSPEKTHKCNYCEKMFHRKDHLKNHLHTHDPNKET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 PYKCIQQDCTKAFVSKYKLQRHMATHSPEKTHKCNYCEKMFHRKDHLKNHLHTHDPNKET 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 FKCEECGKNYNTKLGFKRHLALHAATSGDLTCKVCLQTFESTGVLLEHLKSHAGKSSGGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 FKCEECGKNYNTKLGFKRHLALHAATSGDLTCKVCLQTFESTGVLLEHLKSHAGKSSGGV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 KEKKHQCEHCDRRFYTRKDVRRHMVVHTGRKDFLCQYCAQRFGRKDHLTRHMKKSHNQEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 KEKKHQCEHCDRRFYTRKDVRRHMVVHTGRKDFLCQYCAQRFGRKDHLTRHMKKSHNQEL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 LKVKTEPVDFLDPFTCNVSVPIKDELLPVMSLPSSDLLSKPFTNTLQLNLYNTPFQSMQS :::::::::::::::::::::::::::::::::::.:::::::::::::::::::::::: NP_002 LKVKTEPVDFLDPFTCNVSVPIKDELLPVMSLPSSELLSKPFTNTLQLNLYNTPFQSMQS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 SGSAHQMITTLPLGMTCPIDMDTVHPSHHLSFKYPFSSTSYAISIPEKEQPLKGEIESYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 SGSAHQMITTLPLGMTCPIDMDTVHPSHHLSFKYPFSSTSYAISIPEKEQPLKGEIESYL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 MELQGGVPSSSQDSQASSSSKLGLDPQIGSLDDGAGDLSLSKSSISISDPLNTPALDFSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MELQGGVPSSSQDSQASSSSKLGLDPQIGSLDDGAGDLSLSKSSISISDPLNTPALDFSQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 LFNFIPLNGPPYNPLSVGSLGMSYSQEEAHSSVSQLPPQTQDLQDPANTIGLGSLHSLSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 LFNFIPLNGPPYNPLSVGSLGMSYSQEEAHSSVSQLPPQTQDLQDPANTIGLGSLHSLSA 430 440 450 460 470 480 490 500 pF1KB3 AFTSSLSTSTTLPRFHQAFQ :::::::::::::::::::: NP_002 AFTSSLSTSTTLPRFHQAFQ 490 500 >>NP_001108106 (OMIM: 181030,603026) zinc finger protein (500 aa) initn: 3399 init1: 3399 opt: 3399 Z-score: 1723.1 bits: 328.3 E(85289): 3.1e-89 Smith-Waterman score: 3399; 99.8% identity (100.0% similar) in 500 aa overlap (1-500:1-500) 10 20 30 40 50 60 pF1KB3 MATVIPGDLSEVRDTQKVPSGKRKRGETKPRKNFPCQLCDKAFNSVEKLKVHSYSHTGER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MATVIPGDLSEVRDTQKVPSGKRKRGETKPRKNFPCQLCDKAFNSVEKLKVHSYSHTGER 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 PYKCIQQDCTKAFVSKYKLQRHMATHSPEKTHKCNYCEKMFHRKDHLKNHLHTHDPNKET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PYKCIQQDCTKAFVSKYKLQRHMATHSPEKTHKCNYCEKMFHRKDHLKNHLHTHDPNKET 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 FKCEECGKNYNTKLGFKRHLALHAATSGDLTCKVCLQTFESTGVLLEHLKSHAGKSSGGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FKCEECGKNYNTKLGFKRHLALHAATSGDLTCKVCLQTFESTGVLLEHLKSHAGKSSGGV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 KEKKHQCEHCDRRFYTRKDVRRHMVVHTGRKDFLCQYCAQRFGRKDHLTRHMKKSHNQEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KEKKHQCEHCDRRFYTRKDVRRHMVVHTGRKDFLCQYCAQRFGRKDHLTRHMKKSHNQEL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 LKVKTEPVDFLDPFTCNVSVPIKDELLPVMSLPSSDLLSKPFTNTLQLNLYNTPFQSMQS :::::::::::::::::::::::::::::::::::.:::::::::::::::::::::::: NP_001 LKVKTEPVDFLDPFTCNVSVPIKDELLPVMSLPSSELLSKPFTNTLQLNLYNTPFQSMQS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 SGSAHQMITTLPLGMTCPIDMDTVHPSHHLSFKYPFSSTSYAISIPEKEQPLKGEIESYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SGSAHQMITTLPLGMTCPIDMDTVHPSHHLSFKYPFSSTSYAISIPEKEQPLKGEIESYL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 MELQGGVPSSSQDSQASSSSKLGLDPQIGSLDDGAGDLSLSKSSISISDPLNTPALDFSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MELQGGVPSSSQDSQASSSSKLGLDPQIGSLDDGAGDLSLSKSSISISDPLNTPALDFSQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 LFNFIPLNGPPYNPLSVGSLGMSYSQEEAHSSVSQLPPQTQDLQDPANTIGLGSLHSLSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LFNFIPLNGPPYNPLSVGSLGMSYSQEEAHSSVSQLPPQTQDLQDPANTIGLGSLHSLSA 430 440 450 460 470 480 490 500 pF1KB3 AFTSSLSTSTTLPRFHQAFQ :::::::::::::::::::: NP_001 AFTSSLSTSTTLPRFHQAFQ 490 500 >>XP_016869065 (OMIM: 181030,603026) PREDICTED: zinc fin (500 aa) initn: 3399 init1: 3399 opt: 3399 Z-score: 1723.1 bits: 328.3 E(85289): 3.1e-89 Smith-Waterman score: 3399; 99.8% identity (100.0% similar) in 500 aa overlap (1-500:1-500) 10 20 30 40 50 60 pF1KB3 MATVIPGDLSEVRDTQKVPSGKRKRGETKPRKNFPCQLCDKAFNSVEKLKVHSYSHTGER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MATVIPGDLSEVRDTQKVPSGKRKRGETKPRKNFPCQLCDKAFNSVEKLKVHSYSHTGER 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 PYKCIQQDCTKAFVSKYKLQRHMATHSPEKTHKCNYCEKMFHRKDHLKNHLHTHDPNKET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PYKCIQQDCTKAFVSKYKLQRHMATHSPEKTHKCNYCEKMFHRKDHLKNHLHTHDPNKET 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 FKCEECGKNYNTKLGFKRHLALHAATSGDLTCKVCLQTFESTGVLLEHLKSHAGKSSGGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FKCEECGKNYNTKLGFKRHLALHAATSGDLTCKVCLQTFESTGVLLEHLKSHAGKSSGGV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 KEKKHQCEHCDRRFYTRKDVRRHMVVHTGRKDFLCQYCAQRFGRKDHLTRHMKKSHNQEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KEKKHQCEHCDRRFYTRKDVRRHMVVHTGRKDFLCQYCAQRFGRKDHLTRHMKKSHNQEL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 LKVKTEPVDFLDPFTCNVSVPIKDELLPVMSLPSSDLLSKPFTNTLQLNLYNTPFQSMQS :::::::::::::::::::::::::::::::::::.:::::::::::::::::::::::: XP_016 LKVKTEPVDFLDPFTCNVSVPIKDELLPVMSLPSSELLSKPFTNTLQLNLYNTPFQSMQS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 SGSAHQMITTLPLGMTCPIDMDTVHPSHHLSFKYPFSSTSYAISIPEKEQPLKGEIESYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SGSAHQMITTLPLGMTCPIDMDTVHPSHHLSFKYPFSSTSYAISIPEKEQPLKGEIESYL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 MELQGGVPSSSQDSQASSSSKLGLDPQIGSLDDGAGDLSLSKSSISISDPLNTPALDFSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MELQGGVPSSSQDSQASSSSKLGLDPQIGSLDDGAGDLSLSKSSISISDPLNTPALDFSQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 LFNFIPLNGPPYNPLSVGSLGMSYSQEEAHSSVSQLPPQTQDLQDPANTIGLGSLHSLSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LFNFIPLNGPPYNPLSVGSLGMSYSQEEAHSSVSQLPPQTQDLQDPANTIGLGSLHSLSA 430 440 450 460 470 480 490 500 pF1KB3 AFTSSLSTSTTLPRFHQAFQ :::::::::::::::::::: XP_016 AFTSSLSTSTTLPRFHQAFQ 490 500 >>XP_016869066 (OMIM: 181030,603026) PREDICTED: zinc fin (418 aa) initn: 2831 init1: 2831 opt: 2831 Z-score: 1440.8 bits: 275.9 E(85289): 1.6e-73 Smith-Waterman score: 2831; 99.8% identity (100.0% similar) in 418 aa overlap (83-500:1-418) 60 70 80 90 100 110 pF1KB3 SYSHTGERPYKCIQQDCTKAFVSKYKLQRHMATHSPEKTHKCNYCEKMFHRKDHLKNHLH :::::::::::::::::::::::::::::: XP_016 MATHSPEKTHKCNYCEKMFHRKDHLKNHLH 10 20 30 120 130 140 150 160 170 pF1KB3 THDPNKETFKCEECGKNYNTKLGFKRHLALHAATSGDLTCKVCLQTFESTGVLLEHLKSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 THDPNKETFKCEECGKNYNTKLGFKRHLALHAATSGDLTCKVCLQTFESTGVLLEHLKSH 40 50 60 70 80 90 180 190 200 210 220 230 pF1KB3 AGKSSGGVKEKKHQCEHCDRRFYTRKDVRRHMVVHTGRKDFLCQYCAQRFGRKDHLTRHM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AGKSSGGVKEKKHQCEHCDRRFYTRKDVRRHMVVHTGRKDFLCQYCAQRFGRKDHLTRHM 100 110 120 130 140 150 240 250 260 270 280 290 pF1KB3 KKSHNQELLKVKTEPVDFLDPFTCNVSVPIKDELLPVMSLPSSDLLSKPFTNTLQLNLYN :::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::: XP_016 KKSHNQELLKVKTEPVDFLDPFTCNVSVPIKDELLPVMSLPSSELLSKPFTNTLQLNLYN 160 170 180 190 200 210 300 310 320 330 340 350 pF1KB3 TPFQSMQSSGSAHQMITTLPLGMTCPIDMDTVHPSHHLSFKYPFSSTSYAISIPEKEQPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TPFQSMQSSGSAHQMITTLPLGMTCPIDMDTVHPSHHLSFKYPFSSTSYAISIPEKEQPL 220 230 240 250 260 270 360 370 380 390 400 410 pF1KB3 KGEIESYLMELQGGVPSSSQDSQASSSSKLGLDPQIGSLDDGAGDLSLSKSSISISDPLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KGEIESYLMELQGGVPSSSQDSQASSSSKLGLDPQIGSLDDGAGDLSLSKSSISISDPLN 280 290 300 310 320 330 420 430 440 450 460 470 pF1KB3 TPALDFSQLFNFIPLNGPPYNPLSVGSLGMSYSQEEAHSSVSQLPPQTQDLQDPANTIGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TPALDFSQLFNFIPLNGPPYNPLSVGSLGMSYSQEEAHSSVSQLPPQTQDLQDPANTIGL 340 350 360 370 380 390 480 490 500 pF1KB3 GSLHSLSAAFTSSLSTSTTLPRFHQAFQ :::::::::::::::::::::::::::: XP_016 GSLHSLSAAFTSSLSTSTTLPRFHQAFQ 400 410 >>XP_011515846 (OMIM: 181030,603026) PREDICTED: zinc fin (418 aa) initn: 2831 init1: 2831 opt: 2831 Z-score: 1440.8 bits: 275.9 E(85289): 1.6e-73 Smith-Waterman score: 2831; 99.8% identity (100.0% similar) in 418 aa overlap (83-500:1-418) 60 70 80 90 100 110 pF1KB3 SYSHTGERPYKCIQQDCTKAFVSKYKLQRHMATHSPEKTHKCNYCEKMFHRKDHLKNHLH :::::::::::::::::::::::::::::: XP_011 MATHSPEKTHKCNYCEKMFHRKDHLKNHLH 10 20 30 120 130 140 150 160 170 pF1KB3 THDPNKETFKCEECGKNYNTKLGFKRHLALHAATSGDLTCKVCLQTFESTGVLLEHLKSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 THDPNKETFKCEECGKNYNTKLGFKRHLALHAATSGDLTCKVCLQTFESTGVLLEHLKSH 40 50 60 70 80 90 180 190 200 210 220 230 pF1KB3 AGKSSGGVKEKKHQCEHCDRRFYTRKDVRRHMVVHTGRKDFLCQYCAQRFGRKDHLTRHM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AGKSSGGVKEKKHQCEHCDRRFYTRKDVRRHMVVHTGRKDFLCQYCAQRFGRKDHLTRHM 100 110 120 130 140 150 240 250 260 270 280 290 pF1KB3 KKSHNQELLKVKTEPVDFLDPFTCNVSVPIKDELLPVMSLPSSDLLSKPFTNTLQLNLYN :::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::: XP_011 KKSHNQELLKVKTEPVDFLDPFTCNVSVPIKDELLPVMSLPSSELLSKPFTNTLQLNLYN 160 170 180 190 200 210 300 310 320 330 340 350 pF1KB3 TPFQSMQSSGSAHQMITTLPLGMTCPIDMDTVHPSHHLSFKYPFSSTSYAISIPEKEQPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TPFQSMQSSGSAHQMITTLPLGMTCPIDMDTVHPSHHLSFKYPFSSTSYAISIPEKEQPL 220 230 240 250 260 270 360 370 380 390 400 410 pF1KB3 KGEIESYLMELQGGVPSSSQDSQASSSSKLGLDPQIGSLDDGAGDLSLSKSSISISDPLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KGEIESYLMELQGGVPSSSQDSQASSSSKLGLDPQIGSLDDGAGDLSLSKSSISISDPLN 280 290 300 310 320 330 420 430 440 450 460 470 pF1KB3 TPALDFSQLFNFIPLNGPPYNPLSVGSLGMSYSQEEAHSSVSQLPPQTQDLQDPANTIGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TPALDFSQLFNFIPLNGPPYNPLSVGSLGMSYSQEEAHSSVSQLPPQTQDLQDPANTIGL 340 350 360 370 380 390 480 490 500 pF1KB3 GSLHSLSAAFTSSLSTSTTLPRFHQAFQ :::::::::::::::::::::::::::: XP_011 GSLHSLSAAFTSSLSTSTTLPRFHQAFQ 400 410 >>NP_001108107 (OMIM: 181030,603026) zinc finger protein (418 aa) initn: 2831 init1: 2831 opt: 2831 Z-score: 1440.8 bits: 275.9 E(85289): 1.6e-73 Smith-Waterman score: 2831; 99.8% identity (100.0% similar) in 418 aa overlap (83-500:1-418) 60 70 80 90 100 110 pF1KB3 SYSHTGERPYKCIQQDCTKAFVSKYKLQRHMATHSPEKTHKCNYCEKMFHRKDHLKNHLH :::::::::::::::::::::::::::::: NP_001 MATHSPEKTHKCNYCEKMFHRKDHLKNHLH 10 20 30 120 130 140 150 160 170 pF1KB3 THDPNKETFKCEECGKNYNTKLGFKRHLALHAATSGDLTCKVCLQTFESTGVLLEHLKSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 THDPNKETFKCEECGKNYNTKLGFKRHLALHAATSGDLTCKVCLQTFESTGVLLEHLKSH 40 50 60 70 80 90 180 190 200 210 220 230 pF1KB3 AGKSSGGVKEKKHQCEHCDRRFYTRKDVRRHMVVHTGRKDFLCQYCAQRFGRKDHLTRHM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AGKSSGGVKEKKHQCEHCDRRFYTRKDVRRHMVVHTGRKDFLCQYCAQRFGRKDHLTRHM 100 110 120 130 140 150 240 250 260 270 280 290 pF1KB3 KKSHNQELLKVKTEPVDFLDPFTCNVSVPIKDELLPVMSLPSSDLLSKPFTNTLQLNLYN :::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::: NP_001 KKSHNQELLKVKTEPVDFLDPFTCNVSVPIKDELLPVMSLPSSELLSKPFTNTLQLNLYN 160 170 180 190 200 210 300 310 320 330 340 350 pF1KB3 TPFQSMQSSGSAHQMITTLPLGMTCPIDMDTVHPSHHLSFKYPFSSTSYAISIPEKEQPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TPFQSMQSSGSAHQMITTLPLGMTCPIDMDTVHPSHHLSFKYPFSSTSYAISIPEKEQPL 220 230 240 250 260 270 360 370 380 390 400 410 pF1KB3 KGEIESYLMELQGGVPSSSQDSQASSSSKLGLDPQIGSLDDGAGDLSLSKSSISISDPLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KGEIESYLMELQGGVPSSSQDSQASSSSKLGLDPQIGSLDDGAGDLSLSKSSISISDPLN 280 290 300 310 320 330 420 430 440 450 460 470 pF1KB3 TPALDFSQLFNFIPLNGPPYNPLSVGSLGMSYSQEEAHSSVSQLPPQTQDLQDPANTIGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TPALDFSQLFNFIPLNGPPYNPLSVGSLGMSYSQEEAHSSVSQLPPQTQDLQDPANTIGL 340 350 360 370 380 390 480 490 500 pF1KB3 GSLHSLSAAFTSSLSTSTTLPRFHQAFQ :::::::::::::::::::::::::::: NP_001 GSLHSLSAAFTSSLSTSTTLPRFHQAFQ 400 410 >>XP_011527166 (OMIM: 604866) PREDICTED: zinc finger pro (496 aa) initn: 1626 init1: 1238 opt: 1458 Z-score: 756.0 bits: 149.4 E(85289): 2.3e-35 Smith-Waterman score: 1715; 52.2% identity (75.2% similar) in 504 aa overlap (3-500:6-496) 10 20 30 40 50 pF1KB3 MATVIPGDLSEVRDTQKVPSG--KRKRG-ETKPRKNFPCQLCDKAFNSVEKLKVHSY : .: ...... ..: : :: :.. . . :.. :.. :::. :: XP_011 MTTFFTSVPPWIQDAKQEEEVGWKLVPRPRGREAESQVKCQCEISGTPFSNGEKLRPHSL 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB3 SHTGERPYKCIQQDCTKAFVSKYKLQRHMATHSPEKTHKCNYCEKMFHRKDHLKNHLHTH . .:::.: : : :::.::::: ::::::: .: :.: ::.:::::::::.:::.:: XP_011 PQPEQRPYSCPQLHCGKAFASKYKLYRHMATHSAQKPHQCMYCDKMFHRKDHLRNHLQTH 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB3 DPNKETFKCEECGKNYNTKLGFKRHLALHAATSGDLTCKVCLQTFESTGVLLEHLKSHAG :::::...: :::::::::::..::::.:::.::::.::::::::::: .::::::.:. XP_011 DPNKEALHCSECGKNYNTKLGYRRHLAMHAASSGDLSCKVCLQTFESTQALLEHLKAHSR 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB3 KSSGGVKEKKHQCEHCDRRFYTRKDVRRHMVVHTGRKDFLCQYCAQRFGRKDHLTRHMKK . .::.::::: :.:::::::::::::::.:::::::::::::::::::::::::::.:: XP_011 RVAGGAKEKKHPCDHCDRRFYTRKDVRRHLVVHTGRKDFLCQYCAQRFGRKDHLTRHVKK 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB3 SHNQELLKVKTEPVDFLDPFTCNVSVPIKDELLPVMSLPSSDLL-SKPFTNTLQLNLYNT ::.:::::.::::::.: ..:. .: .:.:: ::. . : :.. .: : . : ...:.. XP_011 SHSQELLKIKTEPVDMLGLLSCSSTVSVKEELSPVLCMASRDVMGTKAFPGMLPMGMYGA 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB3 PFQSMQSSGSAHQMI-TTLPLGMTCPIDMDTVHPSHHLSFKYPFSSTSYAISIPEKEQPL . .: :.: :... .:::.::. :.. . . .: :: ..:::: .:.: : XP_011 HIPTMPSTGVPHSLVHNTLPMGMSYPLESSPISSPAQLPPKYQLGSTSY---LPDK-LP- 310 320 330 340 350 360 370 380 390 400 410 pF1KB3 KGEIESYLMELQGGVPSSSQDSQASSSSKLGLDPQIGSLDDGAGDLSLSKSSISISDPLN : :..:.: :: :.. :: . : .: :: .. . :.:: ..:. : XP_011 KVEVDSFLAELPGSLSLSSAEPQPAS-------PQPAAAAALLDEALLAKSPANLSEALC 360 370 380 390 400 420 430 440 450 460 470 pF1KB3 TPALDFSQLFNFIPLNGPPYNPL-SVGSLGMSYSQEEAHSSVSQLPPQTQDLQDPANTIG . .:::.:..:.::: :: :: ..:.: :.::: ::. .. : : :: .. .. XP_011 AANVDFSHLLGFLPLNLPPCNPPGATGGLVMGYSQAEAQPLLTTLQAQPQDSPGAGGPLN 410 420 430 440 450 460 480 490 500 pF1KB3 LGSLHSLSAAFTSSLSTSTTLPRFHQAFQ .: :::: .:::.:: :::::::::::: XP_011 FGPLHSLPPVFTSGLS-STTLPRFHQAFQ 470 480 490 >>XP_005260493 (OMIM: 604866) PREDICTED: zinc finger pro (496 aa) initn: 1626 init1: 1238 opt: 1458 Z-score: 756.0 bits: 149.4 E(85289): 2.3e-35 Smith-Waterman score: 1715; 52.2% identity (75.2% similar) in 504 aa overlap (3-500:6-496) 10 20 30 40 50 pF1KB3 MATVIPGDLSEVRDTQKVPSG--KRKRG-ETKPRKNFPCQLCDKAFNSVEKLKVHSY : .: ...... ..: : :: :.. . . :.. :.. :::. :: XP_005 MTTFFTSVPPWIQDAKQEEEVGWKLVPRPRGREAESQVKCQCEISGTPFSNGEKLRPHSL 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB3 SHTGERPYKCIQQDCTKAFVSKYKLQRHMATHSPEKTHKCNYCEKMFHRKDHLKNHLHTH . .:::.: : : :::.::::: ::::::: .: :.: ::.:::::::::.:::.:: XP_005 PQPEQRPYSCPQLHCGKAFASKYKLYRHMATHSAQKPHQCMYCDKMFHRKDHLRNHLQTH 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB3 DPNKETFKCEECGKNYNTKLGFKRHLALHAATSGDLTCKVCLQTFESTGVLLEHLKSHAG :::::...: :::::::::::..::::.:::.::::.::::::::::: .::::::.:. XP_005 DPNKEALHCSECGKNYNTKLGYRRHLAMHAASSGDLSCKVCLQTFESTQALLEHLKAHSR 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB3 KSSGGVKEKKHQCEHCDRRFYTRKDVRRHMVVHTGRKDFLCQYCAQRFGRKDHLTRHMKK . .::.::::: :.:::::::::::::::.:::::::::::::::::::::::::::.:: XP_005 RVAGGAKEKKHPCDHCDRRFYTRKDVRRHLVVHTGRKDFLCQYCAQRFGRKDHLTRHVKK 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB3 SHNQELLKVKTEPVDFLDPFTCNVSVPIKDELLPVMSLPSSDLL-SKPFTNTLQLNLYNT ::.:::::.::::::.: ..:. .: .:.:: ::. . : :.. .: : . : ...:.. XP_005 SHSQELLKIKTEPVDMLGLLSCSSTVSVKEELSPVLCMASRDVMGTKAFPGMLPMGMYGA 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB3 PFQSMQSSGSAHQMI-TTLPLGMTCPIDMDTVHPSHHLSFKYPFSSTSYAISIPEKEQPL . .: :.: :... .:::.::. :.. . . .: :: ..:::: .:.: : XP_005 HIPTMPSTGVPHSLVHNTLPMGMSYPLESSPISSPAQLPPKYQLGSTSY---LPDK-LP- 310 320 330 340 350 360 370 380 390 400 410 pF1KB3 KGEIESYLMELQGGVPSSSQDSQASSSSKLGLDPQIGSLDDGAGDLSLSKSSISISDPLN : :..:.: :: :.. :: . : .: :: .. . :.:: ..:. : XP_005 KVEVDSFLAELPGSLSLSSAEPQPAS-------PQPAAAAALLDEALLAKSPANLSEALC 360 370 380 390 400 420 430 440 450 460 470 pF1KB3 TPALDFSQLFNFIPLNGPPYNPL-SVGSLGMSYSQEEAHSSVSQLPPQTQDLQDPANTIG . .:::.:..:.::: :: :: ..:.: :.::: ::. .. : : :: .. .. XP_005 AANVDFSHLLGFLPLNLPPCNPPGATGGLVMGYSQAEAQPLLTTLQAQPQDSPGAGGPLN 410 420 430 440 450 460 480 490 500 pF1KB3 LGSLHSLSAAFTSSLSTSTTLPRFHQAFQ .: :::: .:::.:: :::::::::::: XP_005 FGPLHSLPPVFTSGLS-STTLPRFHQAFQ 470 480 490 >>NP_002648 (OMIM: 604866) zinc finger protein PLAGL2 [H (496 aa) initn: 1626 init1: 1238 opt: 1458 Z-score: 756.0 bits: 149.4 E(85289): 2.3e-35 Smith-Waterman score: 1715; 52.2% identity (75.2% similar) in 504 aa overlap (3-500:6-496) 10 20 30 40 50 pF1KB3 MATVIPGDLSEVRDTQKVPSG--KRKRG-ETKPRKNFPCQLCDKAFNSVEKLKVHSY : .: ...... ..: : :: :.. . . :.. :.. :::. :: NP_002 MTTFFTSVPPWIQDAKQEEEVGWKLVPRPRGREAESQVKCQCEISGTPFSNGEKLRPHSL 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB3 SHTGERPYKCIQQDCTKAFVSKYKLQRHMATHSPEKTHKCNYCEKMFHRKDHLKNHLHTH . .:::.: : : :::.::::: ::::::: .: :.: ::.:::::::::.:::.:: NP_002 PQPEQRPYSCPQLHCGKAFASKYKLYRHMATHSAQKPHQCMYCDKMFHRKDHLRNHLQTH 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB3 DPNKETFKCEECGKNYNTKLGFKRHLALHAATSGDLTCKVCLQTFESTGVLLEHLKSHAG :::::...: :::::::::::..::::.:::.::::.::::::::::: .::::::.:. NP_002 DPNKEALHCSECGKNYNTKLGYRRHLAMHAASSGDLSCKVCLQTFESTQALLEHLKAHSR 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB3 KSSGGVKEKKHQCEHCDRRFYTRKDVRRHMVVHTGRKDFLCQYCAQRFGRKDHLTRHMKK . .::.::::: :.:::::::::::::::.:::::::::::::::::::::::::::.:: NP_002 RVAGGAKEKKHPCDHCDRRFYTRKDVRRHLVVHTGRKDFLCQYCAQRFGRKDHLTRHVKK 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB3 SHNQELLKVKTEPVDFLDPFTCNVSVPIKDELLPVMSLPSSDLL-SKPFTNTLQLNLYNT ::.:::::.::::::.: ..:. .: .:.:: ::. . : :.. .: : . : ...:.. NP_002 SHSQELLKIKTEPVDMLGLLSCSSTVSVKEELSPVLCMASRDVMGTKAFPGMLPMGMYGA 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB3 PFQSMQSSGSAHQMI-TTLPLGMTCPIDMDTVHPSHHLSFKYPFSSTSYAISIPEKEQPL . .: :.: :... .:::.::. :.. . . .: :: ..:::: .:.: : NP_002 HIPTMPSTGVPHSLVHNTLPMGMSYPLESSPISSPAQLPPKYQLGSTSY---LPDK-LP- 310 320 330 340 350 360 370 380 390 400 410 pF1KB3 KGEIESYLMELQGGVPSSSQDSQASSSSKLGLDPQIGSLDDGAGDLSLSKSSISISDPLN : :..:.: :: :.. :: . : .: :: .. . :.:: ..:. : NP_002 KVEVDSFLAELPGSLSLSSAEPQPAS-------PQPAAAAALLDEALLAKSPANLSEALC 360 370 380 390 400 420 430 440 450 460 470 pF1KB3 TPALDFSQLFNFIPLNGPPYNPL-SVGSLGMSYSQEEAHSSVSQLPPQTQDLQDPANTIG . .:::.:..:.::: :: :: ..:.: :.::: ::. .. : : :: .. .. NP_002 AANVDFSHLLGFLPLNLPPCNPPGATGGLVMGYSQAEAQPLLTTLQAQPQDSPGAGGPLN 410 420 430 440 450 460 480 490 500 pF1KB3 LGSLHSLSAAFTSSLSTSTTLPRFHQAFQ .: :::: .:::.:: :::::::::::: NP_002 FGPLHSLPPVFTSGLS-STTLPRFHQAFQ 470 480 490 >>XP_011527165 (OMIM: 604866) PREDICTED: zinc finger pro (496 aa) initn: 1626 init1: 1238 opt: 1458 Z-score: 756.0 bits: 149.4 E(85289): 2.3e-35 Smith-Waterman score: 1715; 52.2% identity (75.2% similar) in 504 aa overlap (3-500:6-496) 10 20 30 40 50 pF1KB3 MATVIPGDLSEVRDTQKVPSG--KRKRG-ETKPRKNFPCQLCDKAFNSVEKLKVHSY : .: ...... ..: : :: :.. . . :.. :.. :::. :: XP_011 MTTFFTSVPPWIQDAKQEEEVGWKLVPRPRGREAESQVKCQCEISGTPFSNGEKLRPHSL 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB3 SHTGERPYKCIQQDCTKAFVSKYKLQRHMATHSPEKTHKCNYCEKMFHRKDHLKNHLHTH . .:::.: : : :::.::::: ::::::: .: :.: ::.:::::::::.:::.:: XP_011 PQPEQRPYSCPQLHCGKAFASKYKLYRHMATHSAQKPHQCMYCDKMFHRKDHLRNHLQTH 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB3 DPNKETFKCEECGKNYNTKLGFKRHLALHAATSGDLTCKVCLQTFESTGVLLEHLKSHAG :::::...: :::::::::::..::::.:::.::::.::::::::::: .::::::.:. XP_011 DPNKEALHCSECGKNYNTKLGYRRHLAMHAASSGDLSCKVCLQTFESTQALLEHLKAHSR 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB3 KSSGGVKEKKHQCEHCDRRFYTRKDVRRHMVVHTGRKDFLCQYCAQRFGRKDHLTRHMKK . .::.::::: :.:::::::::::::::.:::::::::::::::::::::::::::.:: XP_011 RVAGGAKEKKHPCDHCDRRFYTRKDVRRHLVVHTGRKDFLCQYCAQRFGRKDHLTRHVKK 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB3 SHNQELLKVKTEPVDFLDPFTCNVSVPIKDELLPVMSLPSSDLL-SKPFTNTLQLNLYNT ::.:::::.::::::.: ..:. .: .:.:: ::. . : :.. .: : . : ...:.. XP_011 SHSQELLKIKTEPVDMLGLLSCSSTVSVKEELSPVLCMASRDVMGTKAFPGMLPMGMYGA 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB3 PFQSMQSSGSAHQMI-TTLPLGMTCPIDMDTVHPSHHLSFKYPFSSTSYAISIPEKEQPL . .: :.: :... .:::.::. :.. . . .: :: ..:::: .:.: : XP_011 HIPTMPSTGVPHSLVHNTLPMGMSYPLESSPISSPAQLPPKYQLGSTSY---LPDK-LP- 310 320 330 340 350 360 370 380 390 400 410 pF1KB3 KGEIESYLMELQGGVPSSSQDSQASSSSKLGLDPQIGSLDDGAGDLSLSKSSISISDPLN : :..:.: :: :.. :: . : .: :: .. . :.:: ..:. : XP_011 KVEVDSFLAELPGSLSLSSAEPQPAS-------PQPAAAAALLDEALLAKSPANLSEALC 360 370 380 390 400 420 430 440 450 460 470 pF1KB3 TPALDFSQLFNFIPLNGPPYNPL-SVGSLGMSYSQEEAHSSVSQLPPQTQDLQDPANTIG . .:::.:..:.::: :: :: ..:.: :.::: ::. .. : : :: .. .. XP_011 AANVDFSHLLGFLPLNLPPCNPPGATGGLVMGYSQAEAQPLLTTLQAQPQDSPGAGGPLN 410 420 430 440 450 460 480 490 500 pF1KB3 LGSLHSLSAAFTSSLSTSTTLPRFHQAFQ .: :::: .:::.:: :::::::::::: XP_011 FGPLHSLPPVFTSGLS-STTLPRFHQAFQ 470 480 490 500 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 13:59:04 2016 done: Thu Nov 3 13:59:05 2016 Total Scan time: 8.500 Total Display time: 0.090 Function used was FASTA [36.3.4 Apr, 2011]