Result of FASTA (omim) for
pF1KB3818
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3818, 416 aa
1>>>pF1KB3818 416 - 416 aa - 416 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.4121+/-0.000554; mu= -5.1090+/- 0.034
mean_var=660.5406+/-155.746, 0's: 0 Z-trim(118.2): 112 B-trim: 1844 in 1/55
Lambda= 0.049903
statistics sampled from 30878 (31000) to 30878 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.715), E-opt: 0.2 (0.363), width: 16
Scan time: 9.390
The best scores are: opt bits E(85289)
NP_689407 (OMIM: 600863) casein kinase I isoform e ( 416) 2791 216.5 1e-55
NP_001885 (OMIM: 600863) casein kinase I isoform e ( 416) 2791 216.5 1e-55
NP_620693 (OMIM: 600864,615224) casein kinase I is ( 409) 2359 185.4 2.3e-46
XP_005256394 (OMIM: 600864,615224) PREDICTED: case ( 427) 2313 182.1 2.3e-45
NP_001884 (OMIM: 600864,615224) casein kinase I is ( 415) 2309 181.8 2.8e-45
XP_005256393 (OMIM: 600864,615224) PREDICTED: case ( 450) 2309 181.8 2.9e-45
XP_016879688 (OMIM: 600864,615224) PREDICTED: case ( 393) 1961 156.7 9.5e-38
NP_001258670 (OMIM: 600505) casein kinase I isofor ( 325) 1575 128.8 2e-29
NP_001883 (OMIM: 600505) casein kinase I isoform a ( 337) 1575 128.8 2e-29
XP_016864558 (OMIM: 604253) PREDICTED: casein kina ( 424) 1242 105.0 3.8e-22
NP_001257501 (OMIM: 604253) casein kinase I isofor ( 424) 1242 105.0 3.8e-22
XP_005271952 (OMIM: 604253) PREDICTED: casein kina ( 424) 1242 105.0 3.8e-22
XP_005271948 (OMIM: 604253) PREDICTED: casein kina ( 456) 1242 105.0 3.9e-22
XP_005271953 (OMIM: 604253) PREDICTED: casein kina ( 416) 1241 104.9 3.9e-22
NP_001038188 (OMIM: 604253) casein kinase I isofor ( 455) 1231 104.2 6.8e-22
XP_005271949 (OMIM: 604253) PREDICTED: casein kina ( 455) 1231 104.2 6.8e-22
XP_005271951 (OMIM: 604253) PREDICTED: casein kina ( 447) 1229 104.1 7.4e-22
NP_004375 (OMIM: 604253) casein kinase I isoform g ( 447) 1229 104.1 7.4e-22
XP_016864559 (OMIM: 604253) PREDICTED: casein kina ( 415) 1225 103.7 8.7e-22
NP_001026982 (OMIM: 604253) casein kinase I isofor ( 423) 1225 103.7 8.8e-22
NP_001310 (OMIM: 602214) casein kinase I isoform g ( 415) 1203 102.1 2.6e-21
NP_071331 (OMIM: 606274) casein kinase I isoform g ( 422) 1202 102.1 2.8e-21
NP_001316535 (OMIM: 606274) casein kinase I isofor ( 422) 1202 102.1 2.8e-21
NP_001316536 (OMIM: 606274) casein kinase I isofor ( 438) 1202 102.1 2.8e-21
NP_001316534 (OMIM: 606274) casein kinase I isofor ( 475) 1202 102.2 3e-21
XP_005259557 (OMIM: 602214) PREDICTED: casein kina ( 440) 1198 101.8 3.5e-21
XP_016864553 (OMIM: 604253) PREDICTED: casein kina ( 449) 1154 98.7 3.1e-20
XP_016864548 (OMIM: 604253) PREDICTED: casein kina ( 481) 1154 98.7 3.3e-20
XP_016864549 (OMIM: 604253) PREDICTED: casein kina ( 481) 1154 98.7 3.3e-20
XP_016864547 (OMIM: 604253) PREDICTED: casein kina ( 481) 1154 98.7 3.3e-20
XP_016864546 (OMIM: 604253) PREDICTED: casein kina ( 481) 1154 98.7 3.3e-20
XP_016864556 (OMIM: 604253) PREDICTED: casein kina ( 441) 1153 98.6 3.3e-20
XP_016864552 (OMIM: 604253) PREDICTED: casein kina ( 473) 1152 98.6 3.6e-20
XP_016864550 (OMIM: 604253) PREDICTED: casein kina ( 480) 1143 97.9 5.6e-20
XP_016864551 (OMIM: 604253) PREDICTED: casein kina ( 480) 1143 97.9 5.6e-20
XP_016864557 (OMIM: 604253) PREDICTED: casein kina ( 440) 1137 97.4 7.3e-20
XP_016864555 (OMIM: 604253) PREDICTED: casein kina ( 448) 1137 97.4 7.3e-20
XP_016864554 (OMIM: 604253) PREDICTED: casein kina ( 448) 1137 97.4 7.3e-20
XP_016881787 (OMIM: 602214) PREDICTED: casein kina ( 367) 1116 95.8 1.9e-19
XP_005259558 (OMIM: 602214) PREDICTED: casein kina ( 392) 1111 95.5 2.5e-19
NP_001257502 (OMIM: 604253) casein kinase I isofor ( 348) 1095 94.3 5.2e-19
XP_005259556 (OMIM: 602214) PREDICTED: casein kina ( 445) 994 87.2 9.2e-17
XP_016881786 (OMIM: 602214) PREDICTED: casein kina ( 445) 994 87.2 9.2e-17
XP_005259555 (OMIM: 602214) PREDICTED: casein kina ( 445) 994 87.2 9.2e-17
NP_001257503 (OMIM: 604253) casein kinase I isofor ( 311) 977 85.7 1.8e-16
NP_001258671 (OMIM: 600505) casein kinase I isofor ( 276) 844 76.0 1.3e-13
NP_001020276 (OMIM: 600505) casein kinase I isofor ( 365) 844 76.2 1.5e-13
NP_775771 (OMIM: 604432,611695) tau-tubulin kinase (1244) 572 57.5 2.2e-07
XP_006720465 (OMIM: 604432,611695) PREDICTED: tau- (1239) 467 49.9 4.1e-05
XP_005254228 (OMIM: 604432,611695) PREDICTED: tau- (1250) 467 49.9 4.1e-05
>>NP_689407 (OMIM: 600863) casein kinase I isoform epsil (416 aa)
initn: 2791 init1: 2791 opt: 2791 Z-score: 1121.4 bits: 216.5 E(85289): 1e-55
Smith-Waterman score: 2791; 100.0% identity (100.0% similar) in 416 aa overlap (1-416:1-416)
10 20 30 40 50 60
pF1KB3 MELRVGNKYRLGRKIGSGSFGDIYLGANIASGEEVAIKLECVKTKHPQLHIESKFYKMMQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 MELRVGNKYRLGRKIGSGSFGDIYLGANIASGEEVAIKLECVKTKHPQLHIESKFYKMMQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 GGVGIPSIKWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 GGVGIPSIKWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 SKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 SKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 SINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 SINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 CKGYPSEFSTYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGAARN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 CKGYPSEFSTYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGAARN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 PEDVDRERREHEREERMGQLRGSATRALPPGPPTGATANRLRSAAEPVASTPASRIQPAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 PEDVDRERREHEREERMGQLRGSATRALPPGPPTGATANRLRSAAEPVASTPASRIQPAG
310 320 330 340 350 360
370 380 390 400 410
pF1KB3 NTSPRAISRVDRERKVSMRLHRGAPANVSSSDLTGRQEVSRIPASQTSVPFDHLGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 NTSPRAISRVDRERKVSMRLHRGAPANVSSSDLTGRQEVSRIPASQTSVPFDHLGK
370 380 390 400 410
>>NP_001885 (OMIM: 600863) casein kinase I isoform epsil (416 aa)
initn: 2791 init1: 2791 opt: 2791 Z-score: 1121.4 bits: 216.5 E(85289): 1e-55
Smith-Waterman score: 2791; 100.0% identity (100.0% similar) in 416 aa overlap (1-416:1-416)
10 20 30 40 50 60
pF1KB3 MELRVGNKYRLGRKIGSGSFGDIYLGANIASGEEVAIKLECVKTKHPQLHIESKFYKMMQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MELRVGNKYRLGRKIGSGSFGDIYLGANIASGEEVAIKLECVKTKHPQLHIESKFYKMMQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 GGVGIPSIKWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GGVGIPSIKWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 SKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 SINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 CKGYPSEFSTYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGAARN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CKGYPSEFSTYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGAARN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 PEDVDRERREHEREERMGQLRGSATRALPPGPPTGATANRLRSAAEPVASTPASRIQPAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PEDVDRERREHEREERMGQLRGSATRALPPGPPTGATANRLRSAAEPVASTPASRIQPAG
310 320 330 340 350 360
370 380 390 400 410
pF1KB3 NTSPRAISRVDRERKVSMRLHRGAPANVSSSDLTGRQEVSRIPASQTSVPFDHLGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NTSPRAISRVDRERKVSMRLHRGAPANVSSSDLTGRQEVSRIPASQTSVPFDHLGK
370 380 390 400 410
>>NP_620693 (OMIM: 600864,615224) casein kinase I isofor (409 aa)
initn: 2032 init1: 2032 opt: 2359 Z-score: 953.4 bits: 185.4 E(85289): 2.3e-46
Smith-Waterman score: 2359; 84.4% identity (94.2% similar) in 416 aa overlap (1-416:1-409)
10 20 30 40 50 60
pF1KB3 MELRVGNKYRLGRKIGSGSFGDIYLGANIASGEEVAIKLECVKTKHPQLHIESKFYKMMQ
:::::::.::::::::::::::::::..::.:::::::::::::::::::::::.:::::
NP_620 MELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 GGVGIPSIKWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIH
::::::.:.:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 GGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 SKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 SKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 SINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 SINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 CKGYPSEFSTYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGAARN
::::::::.::::::::::::::::::::::::::::::::::::::::::::::::.:
NP_620 CKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGASRA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 PEDVDRERREHEREERMGQLRGSATRALPPGPPTGATANRLRSAAEPVASTPASRIQPAG
.:..::::. ::::. . :. :::.:: .....:::.. : . :: . . ..
NP_620 ADDAERERRD--REERLRHSRNPATRGLP-----STASGRLRGTQEVAPPTPLTPTSHTA
310 320 330 340 350
370 380 390 400 410
pF1KB3 NTSPRAISRVDRERKVSMRLHRGAPANVSSSDLTGRQEVSRIPASQTSVPFDHLGK
::::: .: ..::::::::::::::.:.:::::::::..::. .::.:.::.: ::
NP_620 NTSPRPVSGMERERKVSMRLHRGAPVNISSSDLTGRQDTSRMSTSQNSIPFEHHGK
360 370 380 390 400
>>XP_005256394 (OMIM: 600864,615224) PREDICTED: casein k (427 aa)
initn: 2291 init1: 2032 opt: 2313 Z-score: 935.3 bits: 182.1 E(85289): 2.3e-45
Smith-Waterman score: 2313; 84.8% identity (94.1% similar) in 408 aa overlap (1-408:1-401)
10 20 30 40 50 60
pF1KB3 MELRVGNKYRLGRKIGSGSFGDIYLGANIASGEEVAIKLECVKTKHPQLHIESKFYKMMQ
:::::::.::::::::::::::::::..::.:::::::::::::::::::::::.:::::
XP_005 MELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 GGVGIPSIKWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIH
::::::.:.:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 SKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 SINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 CKGYPSEFSTYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGAARN
::::::::.::::::::::::::::::::::::::::::::::::::::::::::::.:
XP_005 CKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGASRA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 PEDVDRERREHEREERMGQLRGSATRALPPGPPTGATANRLRSAAEPVASTPASRIQPAG
.:..::::. ::::. . :. :::.:: .....:::.. : . :: . . ..
XP_005 ADDAERERRD--REERLRHSRNPATRGLP-----STASGRLRGTQEVAPPTPLTPTSHTA
310 320 330 340 350
370 380 390 400 410
pF1KB3 NTSPRAISRVDRERKVSMRLHRGAPANVSSSDLTGRQEVSRIPASQTSVPFDHLGK
::::: .: ..::::::::::::::.:.:::::::::..::. .:: :
XP_005 NTSPRPVSGMERERKVSMRLHRGAPVNISSSDLTGRQDTSRMSTSQRSRDMASLRLHAAR
360 370 380 390 400 410
XP_005 QGTRCRPQRPRRTY
420
>>NP_001884 (OMIM: 600864,615224) casein kinase I isofor (415 aa)
initn: 2032 init1: 2032 opt: 2309 Z-score: 933.9 bits: 181.8 E(85289): 2.8e-45
Smith-Waterman score: 2309; 85.0% identity (94.3% similar) in 406 aa overlap (1-406:1-399)
10 20 30 40 50 60
pF1KB3 MELRVGNKYRLGRKIGSGSFGDIYLGANIASGEEVAIKLECVKTKHPQLHIESKFYKMMQ
:::::::.::::::::::::::::::..::.:::::::::::::::::::::::.:::::
NP_001 MELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 GGVGIPSIKWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIH
::::::.:.:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 SKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 SINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 CKGYPSEFSTYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGAARN
::::::::.::::::::::::::::::::::::::::::::::::::::::::::::.:
NP_001 CKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGASRA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 PEDVDRERREHEREERMGQLRGSATRALPPGPPTGATANRLRSAAEPVASTPASRIQPAG
.:..::::. ::::. . :. :::.:: .....:::.. : . :: . . ..
NP_001 ADDAERERRD--REERLRHSRNPATRGLP-----STASGRLRGTQEVAPPTPLTPTSHTA
310 320 330 340 350
370 380 390 400 410
pF1KB3 NTSPRAISRVDRERKVSMRLHRGAPANVSSSDLTGRQEVSRIPASQTSVPFDHLGK
::::: .: ..::::::::::::::.:.:::::::::..::. .::
NP_001 NTSPRPVSGMERERKVSMRLHRGAPVNISSSDLTGRQDTSRMSTSQIPGRVASSGLQSVV
360 370 380 390 400 410
NP_001 HR
>>XP_005256393 (OMIM: 600864,615224) PREDICTED: casein k (450 aa)
initn: 2032 init1: 2032 opt: 2309 Z-score: 933.5 bits: 181.8 E(85289): 2.9e-45
Smith-Waterman score: 2309; 85.0% identity (94.3% similar) in 406 aa overlap (1-406:1-399)
10 20 30 40 50 60
pF1KB3 MELRVGNKYRLGRKIGSGSFGDIYLGANIASGEEVAIKLECVKTKHPQLHIESKFYKMMQ
:::::::.::::::::::::::::::..::.:::::::::::::::::::::::.:::::
XP_005 MELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 GGVGIPSIKWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIH
::::::.:.:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 SKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 SINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 CKGYPSEFSTYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGAARN
::::::::.::::::::::::::::::::::::::::::::::::::::::::::::.:
XP_005 CKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGASRA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 PEDVDRERREHEREERMGQLRGSATRALPPGPPTGATANRLRSAAEPVASTPASRIQPAG
.:..::::. ::::. . :. :::.:: .....:::.. : . :: . . ..
XP_005 ADDAERERRD--REERLRHSRNPATRGLP-----STASGRLRGTQEVAPPTPLTPTSHTA
310 320 330 340 350
370 380 390 400 410
pF1KB3 NTSPRAISRVDRERKVSMRLHRGAPANVSSSDLTGRQEVSRIPASQTSVPFDHLGK
::::: .: ..::::::::::::::.:.:::::::::..::. .::
XP_005 NTSPRPVSGMERERKVSMRLHRGAPVNISSSDLTGRQDTSRMSTSQVGAELPGGRWASGY
360 370 380 390 400 410
XP_005 PVRVKSGLWFLQGFFFPFFPPFLRVFNLARVWRLGCR
420 430 440 450
>>XP_016879688 (OMIM: 600864,615224) PREDICTED: casein k (393 aa)
initn: 1684 init1: 1684 opt: 1961 Z-score: 798.7 bits: 156.7 E(85289): 9.5e-38
Smith-Waterman score: 1961; 84.0% identity (93.4% similar) in 349 aa overlap (58-406:1-342)
30 40 50 60 70 80
pF1KB3 NIASGEEVAIKLECVKTKHPQLHIESKFYKMMQGGVGIPSIKWCGAEGDYNVMVMELLGP
:::::::::.:.::::::::::::::::::
XP_016 MMQGGVGIPTIRWCGAEGDYNVMVMELLGP
10 20 30
90 100 110 120 130 140
pF1KB3 SLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYI
40 50 60 70 80 90
150 160 170 180 190 200
pF1KB3 IDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFN
100 110 120 130 140 150
210 220 230 240 250 260
pF1KB3 LGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFSTYLNFCRSLRFDDKPDYS
:::::::::::::::::::::::::::::::::::::::::.::::::::::::::::::
XP_016 LGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYS
160 170 180 190 200 210
270 280 290 300 310 320
pF1KB3 YLRQLFRNLFHRQGFSYDYVFDWNMLKFGAARNPEDVDRERREHEREERMGQLRGSATRA
::::::::::::::::::::::::::::::.: .:..::::. ::::. . :. :::.
XP_016 YLRQLFRNLFHRQGFSYDYVFDWNMLKFGASRAADDAERERRD--REERLRHSRNPATRG
220 230 240 250 260
330 340 350 360 370 380
pF1KB3 LPPGPPTGATANRLRSAAEPVASTPASRIQPAGNTSPRAISRVDRERKVSMRLHRGAPAN
:: .....:::.. : . :: . . ..::::: .: ..::::::::::::::.:
XP_016 LP-----STASGRLRGTQEVAPPTPLTPTSHTANTSPRPVSGMERERKVSMRLHRGAPVN
270 280 290 300 310 320
390 400 410
pF1KB3 VSSSDLTGRQEVSRIPASQTSVPFDHLGK
.:::::::::..::. .::
XP_016 ISSSDLTGRQDTSRMSTSQVGAELPGGRWASGYPVRVKSGLWFLQGFFFPFFPPFLRVFN
330 340 350 360 370 380
>>NP_001258670 (OMIM: 600505) casein kinase I isoform al (325 aa)
initn: 1572 init1: 1572 opt: 1575 Z-score: 649.3 bits: 128.8 E(85289): 2e-29
Smith-Waterman score: 1575; 75.5% identity (91.6% similar) in 298 aa overlap (2-299:10-307)
10 20 30 40 50
pF1KB3 MELRVGNKYRLGRKIGSGSFGDIYLGANIASGEEVAIKLECVKTKHPQLHIE
:. ::.::.: :::::::::::::. ::..:::::.::: :..:::: :
NP_001 MASSSGSKAEFIVGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYE
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB3 SKFYKMMQGGVGIPSIKWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQM
::.::..::::::: :.: : : ::::.::.:::::::::::::::.:..::::.:::::
NP_001 SKLYKILQGGVGIPHIRWYGQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQM
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB3 ISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKN
::::::.:.:::::::.::::::::.:.. : ...::::::::::: ::.:::::::.::
NP_001 ISRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKN
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB3 LTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKK
:::::::::::.:::::::::::.::::::::::: ::::::::::::.::::.:::::
NP_001 LTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKK
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB3 MSTPIEVLCKGYPSEFSTYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNM
::::.::::::.:.::. :::.::.:::.. ::: ::::::: ::. . .:::.:::.:
NP_001 MSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRQLFRILFRTLNHQYDYTFDWTM
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB3 LKFGAARNPEDVDRERREHEREERMGQLRGSATRALPPGPPTGATANRLRSAAEPVASTP
:: ::.
NP_001 LKQKAAQQAASSSGQGQQAQTPTGF
310 320
>>NP_001883 (OMIM: 600505) casein kinase I isoform alpha (337 aa)
initn: 1572 init1: 1572 opt: 1575 Z-score: 649.1 bits: 128.8 E(85289): 2e-29
Smith-Waterman score: 1575; 75.5% identity (91.6% similar) in 298 aa overlap (2-299:10-307)
10 20 30 40 50
pF1KB3 MELRVGNKYRLGRKIGSGSFGDIYLGANIASGEEVAIKLECVKTKHPQLHIE
:. ::.::.: :::::::::::::. ::..:::::.::: :..:::: :
NP_001 MASSSGSKAEFIVGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYE
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB3 SKFYKMMQGGVGIPSIKWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQM
::.::..::::::: :.: : : ::::.::.:::::::::::::::.:..::::.:::::
NP_001 SKLYKILQGGVGIPHIRWYGQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQM
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB3 ISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKN
::::::.:.:::::::.::::::::.:.. : ...::::::::::: ::.:::::::.::
NP_001 ISRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKN
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB3 LTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKK
:::::::::::.:::::::::::.::::::::::: ::::::::::::.::::.:::::
NP_001 LTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKK
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB3 MSTPIEVLCKGYPSEFSTYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNM
::::.::::::.:.::. :::.::.:::.. ::: ::::::: ::. . .:::.:::.:
NP_001 MSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRQLFRILFRTLNHQYDYTFDWTM
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB3 LKFGAARNPEDVDRERREHEREERMGQLRGSATRALPPGPPTGATANRLRSAAEPVASTP
:: ::.
NP_001 LKQKAAQQAASSSGQGQQAQTPTGKQTDKTKSNMKGF
310 320 330
>>XP_016864558 (OMIM: 604253) PREDICTED: casein kinase I (424 aa)
initn: 1243 init1: 663 opt: 1242 Z-score: 518.6 bits: 105.0 E(85289): 3.8e-22
Smith-Waterman score: 1242; 51.2% identity (77.2% similar) in 369 aa overlap (3-361:37-405)
10 20 30
pF1KB3 MELRVGNKYRLGRKIGSGSFGDIYLGANIASG
: :: ..:.:.::: :.::.. :: :. ..
XP_016 DKDKSDDRMARPSGRSGHNTRGTGSSSSGVLMVGPNFRVGKKIGCGNFGELRLGKNLYTN
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB3 EEVAIKLECVKTKHPQLHIESKFYKMMQGGVGIPSIKWCGAEGDYNVMVMELLGPSLEDL
: :::::: .:.. ::::.: .:::.. .: :::.. . : : ::.::.::::::::::
XP_016 EYVAIKLEPMKSRAPQLHLEYRFYKQLGSGDGIPQVYYFGPCGKYNAMVLELLGPSLEDL
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB3 FNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGL--GKKGNLVYIIDF
:..:.: :::::::..: :.:::.::.::::.:.:::::.:::.: .: ....::::
XP_016 FDLCDRTFSLKTVLMIAIQLISRMEYVHSKNLIYRDVKPENFLIGRPGNKTQQVIHIIDF
130 140 150 160 170 180
160 170 180 190 200 210
pF1KB3 GLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGS
::::.: : .:..::::::.:.::::::: ::::::: :::::::::.::...::: ::
XP_016 GLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGS
190 200 210 220 230 240
220 230 240 250 260 270
pF1KB3 LPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFSTYLNFCRSLRFDDKPDYSYLR
:::::::: : ...:..:.. : .:::::::...: :..::: . : : : .::::.:::
XP_016 LPWQGLKADTLKERYQKIGDTKRATPIEVLCENFPEEMATYLRYVRRLDFFEKPDYDYLR
250 260 270 280 290 300
280 290 300 310 320
pF1KB3 QLFRNLFHRQGFSYDYVFDWNMLKF----GAARNPEDVDRERREHEREERMGQLRG----
.:: .:: :.:. .:: .:: .. ::... .. .:. :.....: : ..
XP_016 KLFTDLFDRKGYMFDYEYDWIGKQLPTPVGAVQQDPALSSNREAHQHRDKMQQSKNQVVS
310 320 330 340 350 360
330 340 350 360 370 380
pF1KB3 SATRALPPGPPTGATANRLRSAAEPVASTPASRIQPAGNTSPRAISRVDRERKVSMRLHR
:.. : ::.. .: .: : . : . :
XP_016 STNGELNTDDPTAGRSNAPITAPTEVEVMDETNCQKVLNMWCCCFFKRRKRKTIQRHK
370 380 390 400 410 420
390 400 410
pF1KB3 GAPANVSSSDLTGRQEVSRIPASQTSVPFDHLGK
416 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 13:59:34 2016 done: Thu Nov 3 13:59:36 2016
Total Scan time: 9.390 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]