FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3860, 348 aa 1>>>pF1KB3860 348 - 348 aa - 348 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.3237+/-0.000409; mu= 1.2746+/- 0.025 mean_var=462.5744+/-98.382, 0's: 0 Z-trim(123.8): 1436 B-trim: 0 in 0/56 Lambda= 0.059633 statistics sampled from 42404 (44337) to 42404 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.801), E-opt: 0.2 (0.52), width: 16 Scan time: 9.690 The best scores are: opt bits E(85289) NP_112599 (OMIM: 605858) transcriptional repressor ( 348) 2401 220.4 4.6e-57 NP_003059 (OMIM: 172800,602150,608890) zinc finger ( 268) 599 65.2 1.8e-10 NP_840101 (OMIM: 612741) zinc finger protein SNAI3 ( 292) 581 63.7 5.7e-10 NP_005976 (OMIM: 604238) zinc finger protein SNAI1 ( 264) 512 57.7 3.3e-08 NP_003566 (OMIM: 603397) zinc finger protein 282 i ( 671) 506 57.8 7.9e-08 XP_006716214 (OMIM: 603397) PREDICTED: zinc finger ( 672) 506 57.8 7.9e-08 NP_004211 (OMIM: 608387) zinc finger protein 213 [ ( 459) 424 50.5 8.5e-06 NP_001128127 (OMIM: 608387) zinc finger protein 21 ( 459) 424 50.5 8.5e-06 NP_001276331 (OMIM: 604077) zinc finger protein 13 ( 616) 409 49.4 2.4e-05 XP_016882731 (OMIM: 604077) PREDICTED: zinc finger ( 621) 409 49.4 2.5e-05 XP_016882730 (OMIM: 604077) PREDICTED: zinc finger ( 628) 409 49.4 2.5e-05 XP_016882729 (OMIM: 604077) PREDICTED: zinc finger ( 658) 409 49.5 2.5e-05 NP_001276330 (OMIM: 604077) zinc finger protein 13 ( 658) 409 49.5 2.5e-05 XP_005259268 (OMIM: 604077) PREDICTED: zinc finger ( 670) 409 49.5 2.6e-05 XP_006723426 (OMIM: 604077) PREDICTED: zinc finger ( 670) 409 49.5 2.6e-05 XP_006723425 (OMIM: 604077) PREDICTED: zinc finger ( 670) 409 49.5 2.6e-05 NP_003427 (OMIM: 604077) zinc finger protein 135 i ( 670) 409 49.5 2.6e-05 NP_009065 (OMIM: 604077) zinc finger protein 135 i ( 682) 409 49.5 2.6e-05 XP_011526674 (OMIM: 611811) PREDICTED: zinc finger ( 434) 401 48.5 3.2e-05 XP_011526673 (OMIM: 611811) PREDICTED: zinc finger ( 476) 401 48.6 3.4e-05 XP_016882860 (OMIM: 611811) PREDICTED: zinc finger ( 519) 401 48.6 3.6e-05 XP_016882858 (OMIM: 611811) PREDICTED: zinc finger ( 556) 401 48.7 3.7e-05 XP_011526670 (OMIM: 611811) PREDICTED: zinc finger ( 556) 401 48.7 3.7e-05 XP_011526667 (OMIM: 611811) PREDICTED: zinc finger ( 556) 401 48.7 3.7e-05 XP_011526668 (OMIM: 611811) PREDICTED: zinc finger ( 556) 401 48.7 3.7e-05 XP_011526671 (OMIM: 611811) PREDICTED: zinc finger ( 556) 401 48.7 3.7e-05 XP_011526665 (OMIM: 611811) PREDICTED: zinc finger ( 556) 401 48.7 3.7e-05 XP_011526669 (OMIM: 611811) PREDICTED: zinc finger ( 556) 401 48.7 3.7e-05 XP_005260155 (OMIM: 611811) PREDICTED: zinc finger ( 556) 401 48.7 3.7e-05 XP_016882859 (OMIM: 611811) PREDICTED: zinc finger ( 556) 401 48.7 3.7e-05 XP_016882857 (OMIM: 611811) PREDICTED: zinc finger ( 578) 401 48.7 3.8e-05 XP_011526664 (OMIM: 611811) PREDICTED: zinc finger ( 665) 401 48.8 4.1e-05 NP_115809 (OMIM: 611811) zinc finger protein 333 i ( 665) 401 48.8 4.1e-05 XP_016882856 (OMIM: 611811) PREDICTED: zinc finger ( 665) 401 48.8 4.1e-05 XP_016881869 (OMIM: 613904) PREDICTED: zinc finger ( 527) 395 48.1 5.2e-05 XP_016881871 (OMIM: 613904) PREDICTED: zinc finger ( 527) 395 48.1 5.2e-05 NP_001317411 (OMIM: 613904) zinc finger protein 56 ( 527) 395 48.1 5.2e-05 XP_016881868 (OMIM: 613904) PREDICTED: zinc finger ( 527) 395 48.1 5.2e-05 XP_011525924 (OMIM: 606697) PREDICTED: zinc finger ( 639) 396 48.3 5.4e-05 NP_001278533 (OMIM: 194500) zinc finger protein 2 ( 345) 390 47.4 5.5e-05 NP_001273984 (OMIM: 601260) zinc finger protein wi ( 350) 390 47.4 5.5e-05 NP_005806 (OMIM: 606697) zinc finger protein 443 [ ( 671) 396 48.3 5.6e-05 XP_016881629 (OMIM: 606697) PREDICTED: zinc finger ( 673) 396 48.3 5.6e-05 XP_016881628 (OMIM: 606697) PREDICTED: zinc finger ( 685) 396 48.4 5.6e-05 XP_011525925 (OMIM: 606697) PREDICTED: zinc finger ( 718) 396 48.4 5.8e-05 XP_016881867 (OMIM: 613904) PREDICTED: zinc finger ( 650) 395 48.2 5.8e-05 NP_001269327 (OMIM: 194500) zinc finger protein 2 ( 387) 390 47.5 5.9e-05 XP_016881865 (OMIM: 613904) PREDICTED: zinc finger ( 686) 395 48.3 6e-05 NP_689697 (OMIM: 613904) zinc finger protein 569 i ( 686) 395 48.3 6e-05 XP_016881866 (OMIM: 613904) PREDICTED: zinc finger ( 686) 395 48.3 6e-05 >>NP_112599 (OMIM: 605858) transcriptional repressor scr (348 aa) initn: 2401 init1: 2401 opt: 2401 Z-score: 1145.5 bits: 220.4 E(85289): 4.6e-57 Smith-Waterman score: 2401; 99.7% identity (100.0% similar) in 348 aa overlap (1-348:1-348) 10 20 30 40 50 60 pF1KB3 MPRSFLVKKVKLDAFSSADLESAYGRARSDLGAPLHDKGYLSDYVGPSSVYDGDAEAALL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_112 MPRSFLVKKVKLDAFSSADLESAYGRARSDLGAPLHDKGYLSDYVGPSSVYDGDAEAALL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 KGPSPEPMYAAAVRGELGPAAAGSAPPPTPRPELATAAGGYINGDAAVSEGYAADAFFIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_112 KGPSPEPMYAAAVRGELGPAAAGSAPPPTPRPELATAAGGYINGDAAVSEGYAADAFFIT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 DGRSRRKASNAGSAAAPSTASAAAPDGDAGGGGGAGGRSLGSGPGGRGGTRAGAGTEARA ::::::::::::.::::::::::::::::::::::::::::::::::::::::::::::: NP_112 DGRSRRKASNAGAAAAPSTASAAAPDGDAGGGGGAGGRSLGSGPGGRGGTRAGAGTEARA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 GPGAAGAGGRHACGECGKTYATSSNLSRHKQTHRSLDSQLARRCPTCGKVYVSMPAMAMH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_112 GPGAAGAGGRHACGECGKTYATSSNLSRHKQTHRSLDSQLARRCPTCGKVYVSMPAMAMH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 LLTHDLRHKCGVCGKAFSRPWLLQGHMRSHTGEKPFGCAHCGKAFADRSNLRAHMQTHSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_112 LLTHDLRHKCGVCGKAFSRPWLLQGHMRSHTGEKPFGCAHCGKAFADRSNLRAHMQTHSA 250 260 270 280 290 300 310 320 330 340 pF1KB3 FKHFQCKRCKKSFALKSYLNKHYESACFKGGAGGPAAPAPPQLSPVQA :::::::::::::::::::::::::::::::::::::::::::::::: NP_112 FKHFQCKRCKKSFALKSYLNKHYESACFKGGAGGPAAPAPPQLSPVQA 310 320 330 340 >>NP_003059 (OMIM: 172800,602150,608890) zinc finger pro (268 aa) initn: 794 init1: 575 opt: 599 Z-score: 308.8 bits: 65.2 E(85289): 1.8e-10 Smith-Waterman score: 599; 58.0% identity (78.3% similar) in 138 aa overlap (190-327:127-264) 160 170 180 190 200 210 pF1KB3 LGSGPGGRGGTRAGAGTEARAGPGAAGAGGRHACGECGKTYATSSNLSRHKQTHRSLDSQ . :. :.:::.: :.:..::: : . .:. NP_003 KDHSGSESPISDEEERLQSKLSDPHAIEAEKFQCNLCNKTYSTFSGLAKHKQLHCDAQSR 100 110 120 130 140 150 220 230 240 250 260 270 pF1KB3 LARRCPTCGKVYVSMPAMAMHLLTHDLRHKCGVCGKAFSRPWLLQGHMRSHTGEKPFGCA . : : : :::. :. ::. :: : : .::::::::::::::.:.:::::::.: NP_003 KSFSCKYCDKEYVSLGALKMHIRTHTLPCVCKICGKAFSRPWLLQGHIRTHTGEKPFSCP 160 170 180 190 200 210 280 290 300 310 320 330 pF1KB3 HCGKAFADRSNLRAHMQTHSAFKHFQCKRCKKSFALKSYLNKHYESACFKGGAGGPAAPA ::..:::::::::::.:::: :..::: :.:.:. : :.:: ::.: NP_003 HCNRAFADRSNLRAHLQTHSDVKKYQCKNCSKTFSRMSLLHKHEESGCCVAH 220 230 240 250 260 340 pF1KB3 PPQLSPVQA >>NP_840101 (OMIM: 612741) zinc finger protein SNAI3 [Ho (292 aa) initn: 743 init1: 528 opt: 581 Z-score: 300.0 bits: 63.7 E(85289): 5.7e-10 Smith-Waterman score: 581; 49.7% identity (68.7% similar) in 163 aa overlap (168-330:129-291) 140 150 160 170 180 190 pF1KB3 STASAAAPDGDAGGGGGAGGRSLGSGPGGRGGTRAGAGTEARAGPGAAGAGGRHACGECG : : :: . .. : : : .: NP_840 RAAIVPLKDSLNHLNLPPLLVLPTRWSPTLGPDRHGAPEKLLGAERMPRAPGGFECFHCH 100 110 120 130 140 150 200 210 220 230 240 250 pF1KB3 KTYATSSNLSRHKQTHRSLDSQLARRCPTCGKVYVSMPAMAMHLLTHDLRHKCGVCGKAF : : : ..:.::.: : :. . : : : :.:. :. ::. :: : : .::::: NP_840 KPYHTLAGLARHRQLHCHLQVGRVFTCKYCDKEYTSLGALKMHIRTHTLPCTCKICGKAF 160 170 180 190 200 210 260 270 280 290 300 310 pF1KB3 SRPWLLQGHMRSHTGEKPFGCAHCGKAFADRSNLRAHMQTHSAFKHFQCKRCKKSFALKS :::::::::.:.::::::..:.::..:::::::::::.:::: :...:.:: :.:. : NP_840 SRPWLLQGHVRTHTGEKPYACSHCSRAFADRSNLRAHLQTHSDAKKYRCRRCTKTFSRMS 220 230 240 250 260 270 320 330 340 pF1KB3 YLNKHYESACFKGGAGGPAAPAPPQLSPVQA : .: ::.: : NP_840 LLARHEESGCCPGP 280 290 >>NP_005976 (OMIM: 604238) zinc finger protein SNAI1 [Ho (264 aa) initn: 704 init1: 456 opt: 512 Z-score: 268.4 bits: 57.7 E(85289): 3.3e-08 Smith-Waterman score: 512; 57.9% identity (80.7% similar) in 114 aa overlap (214-327:146-259) 190 200 210 220 230 240 pF1KB3 AAGAGGRHACGECGKTYATSSNLSRHKQTHRSLDSQLARRCPTCGKVYVSMPAMAMHLLT ..:... : : :.: :.:. :. ::. . NP_005 TSVSSLEAEAYAAFPGLGQVPKQLAQLSEAKDLQARKAFNCKYCNKEYLSLGALKMHIRS 120 130 140 150 160 170 250 260 270 280 290 300 pF1KB3 HDLRHKCGVCGKAFSRPWLLQGHMRSHTGEKPFGCAHCGKAFADRSNLRAHMQTHSAFKH : : ::.::::::::::::::.:.:::::::.: ::..:::::::::::.:::: :. NP_005 HTLPCVCGTCGKAFSRPWLLQGHVRTHTGEKPFSCPHCSRAFADRSNLRAHLQTHSDVKK 180 190 200 210 220 230 310 320 330 340 pF1KB3 FQCKRCKKSFALKSYLNKHYESACFKGGAGGPAAPAPPQLSPVQA .::. : ..:. : :.:: ::.: NP_005 YQCQACARTFSRMSLLHKHQESGCSGCPR 240 250 260 >>NP_003566 (OMIM: 603397) zinc finger protein 282 isofo (671 aa) initn: 448 init1: 277 opt: 506 Z-score: 261.6 bits: 57.8 E(85289): 7.9e-08 Smith-Waterman score: 506; 33.0% identity (55.6% similar) in 306 aa overlap (46-345:378-666) 20 30 40 50 60 70 pF1KB3 SSADLESAYGRARSDLGAPLHDKGYLSDYVGPSSVYDGDAEAALLKGPSPEPMYAAAVRG :: . .:: : .: .::: .. :.. NP_003 DIPTDPNSESLISAHDILSWIKQEEQPYPWGPRDSMDG--ELGLDSGPSDSLLM---VKN 350 360 370 380 390 400 80 90 100 110 120 130 pF1KB3 ELGPAAAGSAPPPTP-RPELATAAGGYINGDAAVSE--GYAADAFFITDGRSRRKASNAG :: : : : .:.: . ::.: : . .. :: . .. : NP_003 P-PPAPPQPQPQPQPPQPQLQSQPQPQSLPPIAVAENPGGPPSRGLLDDGF-QVLPGERG 410 420 430 440 450 460 140 150 160 170 180 190 pF1KB3 SAAAPSTASAAAPDGDAGGGGGAGGRSLGSGPGGRGGTRAGAGTEARAGPGAAGAGGR-H :. :: .. .. : . ::::.:: :.: :: :. .: : . :: .. . NP_003 SGEAPPGGDRSTGGGGGDGGGGGGGAEAGTGAGGGCGSCCPGGL--RRSLLLHGARSKPY 470 480 490 500 510 200 210 220 230 240 pF1KB3 ACGECGKTYATSSNLSRHKQTHRSLDSQLARRCPTCGKVYVSMPAMAMHLLTH--DLRHK .: ::::.... ..: : ::: .. .: : : . .. : .:: . .: NP_003 SCPECGKSFGVRKSLIIH---HRSHTKERPYECAECEKSFNCHSGLIRHQMTHRGERPYK 520 530 540 550 560 570 250 260 270 280 290 300 pF1KB3 CGVCGKAFSRPWLLQGHMRSHTGEKPFGCAHCGKAFADRSNLRAHMQTHSAFKHFQCKRC :. : :..:: ::.:.: ::::.:: :: :::.: ..:: :.. :.. . . : .: NP_003 CSECEKTYSRKEHLQNHQRLHTGERPFQCALCGKSFIRKQNLLKHQRIHTGERPYTCGEC 580 590 600 610 620 630 310 320 330 340 pF1KB3 KKSFALKSYLNKHYESACFKGGAGGPAAPAPPQLSPVQA ::: : :. : .. .:::. :: :: : NP_003 GKSFRYKESLKDH-----LRVHSGGPGPGAPRQLPPPPERD 640 650 660 670 >>XP_006716214 (OMIM: 603397) PREDICTED: zinc finger pro (672 aa) initn: 448 init1: 277 opt: 506 Z-score: 261.6 bits: 57.8 E(85289): 7.9e-08 Smith-Waterman score: 506; 33.0% identity (55.6% similar) in 306 aa overlap (46-345:379-667) 20 30 40 50 60 70 pF1KB3 SSADLESAYGRARSDLGAPLHDKGYLSDYVGPSSVYDGDAEAALLKGPSPEPMYAAAVRG :: . .:: : .: .::: .. :.. XP_006 DIPTDPNSESLISAHDILSWIKQEEQPYPWGPRDSMDG--ELGLDSGPSDSLLM---VKN 350 360 370 380 390 400 80 90 100 110 120 130 pF1KB3 ELGPAAAGSAPPPTP-RPELATAAGGYINGDAAVSE--GYAADAFFITDGRSRRKASNAG :: : : : .:.: . ::.: : . .. :: . .. : XP_006 P-PPAPPQPQPQPQPPQPQLQSQPQPQSLPPIAVAENPGGPPSRGLLDDGF-QVLPGERG 410 420 430 440 450 460 140 150 160 170 180 190 pF1KB3 SAAAPSTASAAAPDGDAGGGGGAGGRSLGSGPGGRGGTRAGAGTEARAGPGAAGAGGR-H :. :: .. .. : . ::::.:: :.: :: :. .: : . :: .. . XP_006 SGEAPPGGDRSTGGGGGDGGGGGGGAEAGTGAGGGCGSCCPGGL--RRSLLLHGARSKPY 470 480 490 500 510 200 210 220 230 240 pF1KB3 ACGECGKTYATSSNLSRHKQTHRSLDSQLARRCPTCGKVYVSMPAMAMHLLTH--DLRHK .: ::::.... ..: : ::: .. .: : : . .. : .:: . .: XP_006 SCPECGKSFGVRKSLIIH---HRSHTKERPYECAECEKSFNCHSGLIRHQMTHRGERPYK 520 530 540 550 560 570 250 260 270 280 290 300 pF1KB3 CGVCGKAFSRPWLLQGHMRSHTGEKPFGCAHCGKAFADRSNLRAHMQTHSAFKHFQCKRC :. : :..:: ::.:.: ::::.:: :: :::.: ..:: :.. :.. . . : .: XP_006 CSECEKTYSRKEHLQNHQRLHTGERPFQCALCGKSFIRKQNLLKHQRIHTGERPYTCGEC 580 590 600 610 620 630 310 320 330 340 pF1KB3 KKSFALKSYLNKHYESACFKGGAGGPAAPAPPQLSPVQA ::: : :. : .. .:::. :: :: : XP_006 GKSFRYKESLKDH-----LRVHSGGPGPGAPRQLPPPPERD 640 650 660 670 >>NP_004211 (OMIM: 608387) zinc finger protein 213 [Homo (459 aa) initn: 615 init1: 258 opt: 424 Z-score: 225.1 bits: 50.5 E(85289): 8.5e-06 Smith-Waterman score: 424; 30.8% identity (52.4% similar) in 328 aa overlap (7-322:128-447) 10 20 30 pF1KB3 MPRSFLVKKVKLDAFSSADLESAYGRARSDLGAPLH :: . :. : : ::. . : : NP_004 PGEIQGWVREQHPGSGEEAVALVEDLQKQPVKAWRQDVPSEEAEPEAAGRGSQATGPPPT 100 110 120 130 140 150 40 50 60 70 80 90 pF1KB3 DKGYLSDYVGPSSVYDGDAEA-ALLKGPSP-EPMYAAAVRGELGPAAAGSAPPPTPRPEL . : :. .. .:. :::: : : . : : ::.: :. : : : NP_004 VGARRRPSV-PQEQHSHSAQPPALLKEGRPGETTDTCFVSGVHGPVALGDIPFYFSREEW 160 170 180 190 200 210 100 110 120 130 140 pF1KB3 AT--AAGGYINGDAAVSEGYAADAFFITDGRSRRKASNA------GSAAAPSTASAAAPD .: : . : .. . : :.:... . :.... :.: . . NP_004 GTLDPAQRDLFWDIKRENSRNTTLGFGLKGQSEKSLLQEMVPVVPGQTGSDVTVSWSPEE 220 230 240 250 260 270 150 160 170 180 190 200 pF1KB3 GDAGGGGGAGGRSLGSGPGGRGGTRAGAGTEARAGPGAAGAGGRHACGECGKTYATSSNL ..: . . .:: :.: : :. : : : :.::.::: . .:.: NP_004 AEAWESENRPRAALGPVVGARRGR---PPTRRRQFRDLA-AEKPHSCGQCGKRFRWGSDL 280 290 300 310 320 330 210 220 230 240 250 260 pF1KB3 SRHKQTHRSLDSQLARRCPTCGKVYVSMPAMAMHLLTHDLRH--KCGVCGKAFSRPWLLQ .::..:: . . ..:: : : . : .. : .: .. .:. :::.::: : NP_004 ARHQRTHTG---EKPHKCPECDKSFRSSSDLVRHQGVHTGEKPFSCSECGKSFSRSAYLA 340 350 360 370 380 270 280 290 300 310 320 pF1KB3 GHMRSHTGEKPFGCAHCGKAFADRSNLRAHMQTHSAFKHFQCKRCKKSFALKSYLNKHYE :.: :::::::::. :::.:. :: : : ..:.. . : : .: ::: ...: : NP_004 DHQRIHTGEKPFGCSDCGKSFSLRSYLLDHRRVHTGERPFGCGECDKSFKQRAHLIAHQS 390 400 410 420 430 440 330 340 pF1KB3 SACFKGGAGGPAAPAPPQLSPVQA NP_004 LHAKMAQPVG 450 >>NP_001128127 (OMIM: 608387) zinc finger protein 213 [H (459 aa) initn: 615 init1: 258 opt: 424 Z-score: 225.1 bits: 50.5 E(85289): 8.5e-06 Smith-Waterman score: 424; 30.8% identity (52.4% similar) in 328 aa overlap (7-322:128-447) 10 20 30 pF1KB3 MPRSFLVKKVKLDAFSSADLESAYGRARSDLGAPLH :: . :. : : ::. . : : NP_001 PGEIQGWVREQHPGSGEEAVALVEDLQKQPVKAWRQDVPSEEAEPEAAGRGSQATGPPPT 100 110 120 130 140 150 40 50 60 70 80 90 pF1KB3 DKGYLSDYVGPSSVYDGDAEA-ALLKGPSP-EPMYAAAVRGELGPAAAGSAPPPTPRPEL . : :. .. .:. :::: : : . : : ::.: :. : : : NP_001 VGARRRPSV-PQEQHSHSAQPPALLKEGRPGETTDTCFVSGVHGPVALGDIPFYFSREEW 160 170 180 190 200 210 100 110 120 130 140 pF1KB3 AT--AAGGYINGDAAVSEGYAADAFFITDGRSRRKASNA------GSAAAPSTASAAAPD .: : . : .. . : :.:... . :.... :.: . . NP_001 GTLDPAQRDLFWDIKRENSRNTTLGFGLKGQSEKSLLQEMVPVVPGQTGSDVTVSWSPEE 220 230 240 250 260 270 150 160 170 180 190 200 pF1KB3 GDAGGGGGAGGRSLGSGPGGRGGTRAGAGTEARAGPGAAGAGGRHACGECGKTYATSSNL ..: . . .:: :.: : :. : : : :.::.::: . .:.: NP_001 AEAWESENRPRAALGPVVGARRGR---PPTRRRQFRDLA-AEKPHSCGQCGKRFRWGSDL 280 290 300 310 320 330 210 220 230 240 250 260 pF1KB3 SRHKQTHRSLDSQLARRCPTCGKVYVSMPAMAMHLLTHDLRH--KCGVCGKAFSRPWLLQ .::..:: . . ..:: : : . : .. : .: .. .:. :::.::: : NP_001 ARHQRTHTG---EKPHKCPECDKSFRSSSDLVRHQGVHTGEKPFSCSECGKSFSRSAYLA 340 350 360 370 380 270 280 290 300 310 320 pF1KB3 GHMRSHTGEKPFGCAHCGKAFADRSNLRAHMQTHSAFKHFQCKRCKKSFALKSYLNKHYE :.: :::::::::. :::.:. :: : : ..:.. . : : .: ::: ...: : NP_001 DHQRIHTGEKPFGCSDCGKSFSLRSYLLDHRRVHTGERPFGCGECDKSFKQRAHLIAHQS 390 400 410 420 430 440 330 340 pF1KB3 SACFKGGAGGPAAPAPPQLSPVQA NP_001 LHAKMAQPVG 450 >>NP_001276331 (OMIM: 604077) zinc finger protein 135 is (616 aa) initn: 1318 init1: 280 opt: 409 Z-score: 216.8 bits: 49.4 E(85289): 2.4e-05 Smith-Waterman score: 409; 40.3% identity (70.9% similar) in 134 aa overlap (191-322:312-442) 170 180 190 200 210 220 pF1KB3 GSGPGGRGGTRAGAGTEARAGPGAAGAGGRHACGECGKTYATSSNLSRHKQTHRSLDSQL . ::::::... ::.:..:.. : . . NP_001 KPYECSECGKAFRQSIHLTQHLRIHTGEKPYQCGECGKAFSHSSSLTKHQRIHTG---EK 290 300 310 320 330 230 240 250 260 270 pF1KB3 ARRCPTCGKVYVSMPAMAMHLLTH--DLRHKCGVCGKAFSRPWLLQGHMRSHTGEKPFGC .: :::..... . .: :: . ..:: ::::::. :: : : ::::::.:: NP_001 PYECHECGKAFTQITPLIQHQRTHTGEKPYECGECGKAFSQSTLLTEHRRIHTGEKPYGC 340 350 360 370 380 390 280 290 300 310 320 330 pF1KB3 AHCGKAFADRSNLRAHMQTHSAFKHFQCKRCKKSFALKSYLNKHYESACFKGGAGGPAAP .:::.:. :.: : .::.. : ..:..: :.: ...:..: NP_001 NECGKTFSHSSSLSQHERTHTGEKPYECSQCGKAFRQSTHLTQHQRIHTGEKPYECNDCG 400 410 420 430 440 450 340 pF1KB3 APPQLSPVQA NP_001 KAFSHSSSLTKHQRIHTGEKPYECNQCGRAFSQLAPLIQHQRIHTGEKPYECNQCGRAFS 460 470 480 490 500 510 >-- initn: 980 init1: 250 opt: 367 Z-score: 197.3 bits: 45.8 E(85289): 0.0003 Smith-Waterman score: 367; 35.8% identity (68.7% similar) in 134 aa overlap (191-322:452-582) 170 180 190 200 210 220 pF1KB3 GSGPGGRGGTRAGAGTEARAGPGAAGAGGRHACGECGKTYATSSNLSRHKQTHRSLDSQL . :..:::... ::.:..:.. : . . NP_001 KPYECSQCGKAFRQSTHLTQHQRIHTGEKPYECNDCGKAFSHSSSLTKHQRIHTG---EK 430 440 450 460 470 230 240 250 260 270 pF1KB3 ARRCPTCGKVYVSMPAMAMHLLTH--DLRHKCGVCGKAFSRPWLLQGHMRSHTGEKPFGC .: ::... .. . .: : . ..:. ::.:::. :: :.: :: :::.:: NP_001 PYECNQCGRAFSQLAPLIQHQRIHTGEKPYECNQCGRAFSQSSLLIEHQRIHTKEKPYGC 480 490 500 510 520 530 280 290 300 310 320 330 pF1KB3 AHCGKAFADRSNLRAHMQTHSAFKHFQCKRCKKSFALKSYLNKHYESACFKGGAGGPAAP .:::.:. :.: : .::.. : ..:. : ::: ...:..: NP_001 NECGKSFSHSSSLSQHERTHTGEKPYECHDCGKSFRQSTHLTQHRRIHTGEKPYACRDCG 540 550 560 570 580 590 340 pF1KB3 APPQLSPVQA NP_001 KAFTHSSSLTKHQRTHTG 600 610 >>XP_016882731 (OMIM: 604077) PREDICTED: zinc finger pro (621 aa) initn: 1318 init1: 280 opt: 409 Z-score: 216.8 bits: 49.4 E(85289): 2.5e-05 Smith-Waterman score: 409; 40.3% identity (70.9% similar) in 134 aa overlap (191-322:317-447) 170 180 190 200 210 220 pF1KB3 GSGPGGRGGTRAGAGTEARAGPGAAGAGGRHACGECGKTYATSSNLSRHKQTHRSLDSQL . ::::::... ::.:..:.. : . . XP_016 KPYECSECGKAFRQSIHLTQHLRIHTGEKPYQCGECGKAFSHSSSLTKHQRIHTG---EK 290 300 310 320 330 340 230 240 250 260 270 pF1KB3 ARRCPTCGKVYVSMPAMAMHLLTH--DLRHKCGVCGKAFSRPWLLQGHMRSHTGEKPFGC .: :::..... . .: :: . ..:: ::::::. :: : : ::::::.:: XP_016 PYECHECGKAFTQITPLIQHQRTHTGEKPYECGECGKAFSQSTLLTEHRRIHTGEKPYGC 350 360 370 380 390 400 280 290 300 310 320 330 pF1KB3 AHCGKAFADRSNLRAHMQTHSAFKHFQCKRCKKSFALKSYLNKHYESACFKGGAGGPAAP .:::.:. :.: : .::.. : ..:..: :.: ...:..: XP_016 NECGKTFSHSSSLSQHERTHTGEKPYECSQCGKAFRQSTHLTQHQRIHTGEKPYECNDCG 410 420 430 440 450 460 340 pF1KB3 APPQLSPVQA XP_016 KAFSHSSSLTKHQRIHTGEKPYECNQCGRAFSQLAPLIQHQRIHTGEKPYECNQCGRAFS 470 480 490 500 510 520 >-- initn: 980 init1: 250 opt: 367 Z-score: 197.3 bits: 45.8 E(85289): 0.0003 Smith-Waterman score: 367; 35.8% identity (68.7% similar) in 134 aa overlap (191-322:457-587) 170 180 190 200 210 220 pF1KB3 GSGPGGRGGTRAGAGTEARAGPGAAGAGGRHACGECGKTYATSSNLSRHKQTHRSLDSQL . :..:::... ::.:..:.. : . . XP_016 KPYECSQCGKAFRQSTHLTQHQRIHTGEKPYECNDCGKAFSHSSSLTKHQRIHTG---EK 430 440 450 460 470 480 230 240 250 260 270 pF1KB3 ARRCPTCGKVYVSMPAMAMHLLTH--DLRHKCGVCGKAFSRPWLLQGHMRSHTGEKPFGC .: ::... .. . .: : . ..:. ::.:::. :: :.: :: :::.:: XP_016 PYECNQCGRAFSQLAPLIQHQRIHTGEKPYECNQCGRAFSQSSLLIEHQRIHTKEKPYGC 490 500 510 520 530 540 280 290 300 310 320 330 pF1KB3 AHCGKAFADRSNLRAHMQTHSAFKHFQCKRCKKSFALKSYLNKHYESACFKGGAGGPAAP .:::.:. :.: : .::.. : ..:. : ::: ...:..: XP_016 NECGKSFSHSSSLSQHERTHTGEKPYECHDCGKSFRQSTHLTQHRRIHTGEKPYACRDCG 550 560 570 580 590 600 340 pF1KB3 APPQLSPVQA XP_016 KAFTHSSSLTKHQRTHTG 610 620 348 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 14:04:46 2016 done: Thu Nov 3 14:04:47 2016 Total Scan time: 9.690 Total Display time: 0.050 Function used was FASTA [36.3.4 Apr, 2011]