FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3867, 354 aa 1>>>pF1KB3867 354 - 354 aa - 354 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.5454+/-0.000511; mu= 20.7362+/- 0.032 mean_var=68.3300+/-14.150, 0's: 0 Z-trim(109.4): 92 B-trim: 1162 in 2/48 Lambda= 0.155156 statistics sampled from 17447 (17543) to 17447 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.556), E-opt: 0.2 (0.206), width: 16 Scan time: 7.110 The best scores are: opt bits E(85289) NP_066268 (OMIM: 139311,615473) guanine nucleotide ( 354) 2331 531.2 1.3e-150 NP_620073 (OMIM: 139311,615473) guanine nucleotide ( 354) 2203 502.6 5.5e-142 XP_011521305 (OMIM: 139311,615473) PREDICTED: guan ( 312) 2009 459.1 6e-129 NP_002060 (OMIM: 139310) guanine nucleotide-bindin ( 354) 1691 388.0 1.8e-107 NP_006487 (OMIM: 139370,602483) guanine nucleotide ( 354) 1667 382.6 7.2e-106 NP_002061 (OMIM: 139360,192605) guanine nucleotide ( 355) 1646 377.9 1.9e-104 NP_001095856 (OMIM: 139395) guanine nucleotide-bin ( 354) 1470 338.5 1.4e-92 NP_001159897 (OMIM: 139360,192605) guanine nucleot ( 318) 1468 338.0 1.7e-92 NP_001269548 (OMIM: 139360,192605) guanine nucleot ( 339) 1468 338.0 1.8e-92 NP_001269549 (OMIM: 139360,192605) guanine nucleot ( 339) 1468 338.0 1.8e-92 XP_011539566 (OMIM: 139340,613856) PREDICTED: guan ( 354) 1454 334.9 1.6e-91 NP_005263 (OMIM: 139340,613856) guanine nucleotide ( 354) 1454 334.9 1.6e-91 NP_653082 (OMIM: 139330,610444,616389) guanine nuc ( 350) 1445 332.9 6.5e-91 NP_000163 (OMIM: 139330,610444,616389) guanine nuc ( 350) 1445 332.9 6.5e-91 NP_001243343 (OMIM: 139310) guanine nucleotide-bin ( 302) 1430 329.5 6e-90 NP_001269546 (OMIM: 139360,192605) guanine nucleot ( 303) 1389 320.3 3.5e-87 NP_002064 (OMIM: 139160) guanine nucleotide-bindin ( 355) 1389 320.4 3.9e-87 NP_001269547 (OMIM: 139360,192605) guanine nucleot ( 274) 1248 288.7 1e-77 XP_011514426 (OMIM: 139395) PREDICTED: guanine nuc ( 297) 1200 278.0 1.9e-74 NP_004288 (OMIM: 604397) guanine nucleotide-bindin ( 355) 1142 265.1 1.7e-70 NP_002063 (OMIM: 163000,185300,600998) guanine nuc ( 359) 1116 259.3 9.8e-69 NP_002058 (OMIM: 139313) guanine nucleotide-bindin ( 359) 1101 255.9 1e-67 XP_016870830 (OMIM: 604397) PREDICTED: guanine nuc ( 301) 975 227.6 2.8e-59 XP_016870117 (OMIM: 163000,185300,600998) PREDICTE ( 301) 957 223.6 4.5e-58 NP_006563 (OMIM: 604406) guanine nucleotide-bindin ( 377) 947 221.4 2.5e-57 NP_031379 (OMIM: 604394) guanine nucleotide-bindin ( 381) 933 218.3 2.2e-56 XP_016884275 (OMIM: 139160) PREDICTED: guanine nuc ( 307) 867 203.4 5.3e-52 NP_002059 (OMIM: 139314) guanine nucleotide-bindin ( 374) 843 198.2 2.5e-50 NP_001135811 (OMIM: 139312,615073) guanine nucleot ( 381) 837 196.8 6.5e-50 NP_001248372 (OMIM: 139312,615073) guanine nucleot ( 381) 837 196.8 6.5e-50 XP_011517526 (OMIM: 604397) PREDICTED: guanine nuc ( 237) 832 195.5 1e-49 NP_536351 (OMIM: 102200,103580,139320,166350,17480 ( 380) 834 196.2 1e-49 XP_016883302 (OMIM: 102200,103580,139320,166350,17 (1023) 837 197.2 1.3e-49 NP_001070957 (OMIM: 102200,103580,139320,166350,17 ( 379) 832 195.7 1.4e-49 XP_016883303 (OMIM: 102200,103580,139320,166350,17 (1022) 835 196.8 1.8e-49 NP_892023 (OMIM: 139312,615073) guanine nucleotide ( 458) 826 194.4 4.1e-49 XP_016883304 (OMIM: 102200,103580,139320,166350,17 ( 347) 768 181.3 2.7e-45 XP_011513590 (OMIM: 604394) PREDICTED: guanine nuc ( 284) 766 180.8 3.2e-45 NP_001269370 (OMIM: 604394) guanine nucleotide-bin ( 322) 763 180.2 5.6e-45 XP_016867497 (OMIM: 604394) PREDICTED: guanine nuc ( 253) 744 175.8 9e-44 NP_001269354 (OMIM: 604406) guanine nucleotide-bin ( 282) 722 171.0 2.9e-42 XP_016883308 (OMIM: 102200,103580,139320,166350,17 ( 320) 687 163.2 7.3e-40 XP_016883307 (OMIM: 102200,103580,139320,166350,17 ( 320) 687 163.2 7.3e-40 XP_016883306 (OMIM: 102200,103580,139320,166350,17 ( 320) 687 163.2 7.3e-40 NP_000507 (OMIM: 102200,103580,139320,166350,17480 ( 394) 659 157.0 6.5e-38 NP_001296790 (OMIM: 102200,103580,139320,166350,17 ( 335) 654 155.8 1.3e-37 NP_001296769 (OMIM: 102200,103580,139320,166350,17 ( 335) 654 155.8 1.3e-37 NP_536350 (OMIM: 102200,103580,139320,166350,17480 (1037) 659 157.4 1.3e-37 NP_001070956 (OMIM: 102200,103580,139320,166350,17 ( 395) 652 155.4 1.9e-37 NP_001269369 (OMIM: 604394) guanine nucleotide-bin ( 305) 648 154.4 3e-37 >>NP_066268 (OMIM: 139311,615473) guanine nucleotide-bin (354 aa) initn: 2331 init1: 2331 opt: 2331 Z-score: 2824.9 bits: 531.2 E(85289): 1.3e-150 Smith-Waterman score: 2331; 100.0% identity (100.0% similar) in 354 aa overlap (1-354:1-354) 10 20 30 40 50 60 pF1KB3 MGCTLSAEERAALERSKAIEKNLKEDGISAAKDVKLLLLGAGESGKSTIVKQMKIIHEDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_066 MGCTLSAEERAALERSKAIEKNLKEDGISAAKDVKLLLLGAGESGKSTIVKQMKIIHEDG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 FSGEDVKQYKPVVYSNTIQSLAAIVRAMDTLGIEYGDKERKADAKMVCDVVSRMEDTEPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_066 FSGEDVKQYKPVVYSNTIQSLAAIVRAMDTLGIEYGDKERKADAKMVCDVVSRMEDTEPF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 SAELLSAMMRLWGDSGIQECFNRSREYQLNDSAKYYLDSLDRIGAADYQPTEQDILRTRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_066 SAELLSAMMRLWGDSGIQECFNRSREYQLNDSAKYYLDSLDRIGAADYQPTEQDILRTRV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 KTTGIVETHFTFKNLHFRLFDVGGQRSERKKWIHCFEDVTAIIFCVALSGYDQVLHEDET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_066 KTTGIVETHFTFKNLHFRLFDVGGQRSERKKWIHCFEDVTAIIFCVALSGYDQVLHEDET 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 TNRMHESLMLFDSICNNKFFIDTSIILFLNKKDLFGEKIKKSPLTICFPEYTGPNTYEDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_066 TNRMHESLMLFDSICNNKFFIDTSIILFLNKKDLFGEKIKKSPLTICFPEYTGPNTYEDA 250 260 270 280 290 300 310 320 330 340 350 pF1KB3 AAYIQAQFESKNRSPNKEIYCHMTCATDTNNIQVVFDAVTDIIIANNLRGCGLY :::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_066 AAYIQAQFESKNRSPNKEIYCHMTCATDTNNIQVVFDAVTDIIIANNLRGCGLY 310 320 330 340 350 >>NP_620073 (OMIM: 139311,615473) guanine nucleotide-bin (354 aa) initn: 2203 init1: 2203 opt: 2203 Z-score: 2670.0 bits: 502.6 E(85289): 5.5e-142 Smith-Waterman score: 2203; 94.4% identity (98.0% similar) in 354 aa overlap (1-354:1-354) 10 20 30 40 50 60 pF1KB3 MGCTLSAEERAALERSKAIEKNLKEDGISAAKDVKLLLLGAGESGKSTIVKQMKIIHEDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_620 MGCTLSAEERAALERSKAIEKNLKEDGISAAKDVKLLLLGAGESGKSTIVKQMKIIHEDG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 FSGEDVKQYKPVVYSNTIQSLAAIVRAMDTLGIEYGDKERKADAKMVCDVVSRMEDTEPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_620 FSGEDVKQYKPVVYSNTIQSLAAIVRAMDTLGIEYGDKERKADAKMVCDVVSRMEDTEPF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 SAELLSAMMRLWGDSGIQECFNRSREYQLNDSAKYYLDSLDRIGAADYQPTEQDILRTRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_620 SAELLSAMMRLWGDSGIQECFNRSREYQLNDSAKYYLDSLDRIGAADYQPTEQDILRTRV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 KTTGIVETHFTFKNLHFRLFDVGGQRSERKKWIHCFEDVTAIIFCVALSGYDQVLHEDET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_620 KTTGIVETHFTFKNLHFRLFDVGGQRSERKKWIHCFEDVTAIIFCVALSGYDQVLHEDET 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 TNRMHESLMLFDSICNNKFFIDTSIILFLNKKDLFGEKIKKSPLTICFPEYTGPNTYEDA :::::::: :::::::::.: ::::::::::::.: ::::::::::::::::::... .: NP_620 TNRMHESLKLFDSICNNKWFTDTSIILFLNKKDIFEEKIKKSPLTICFPEYTGPSAFTEA 250 260 270 280 290 300 310 320 330 340 350 pF1KB3 AAYIQAQFESKNRSPNKEIYCHMTCATDTNNIQVVFDAVTDIIIANNLRGCGLY .::::::.::::.: .:::: :.:::::::::: :::::::.:::.:::::::: NP_620 VAYIQAQYESKNKSAHKEIYTHVTCATDTNNIQFVFDAVTDVIIAKNLRGCGLY 310 320 330 340 350 >>XP_011521305 (OMIM: 139311,615473) PREDICTED: guanine (312 aa) initn: 2009 init1: 2009 opt: 2009 Z-score: 2436.0 bits: 459.1 E(85289): 6e-129 Smith-Waterman score: 2009; 99.7% identity (100.0% similar) in 301 aa overlap (54-354:12-312) 30 40 50 60 70 80 pF1KB3 KEDGISAAKDVKLLLLGAGESGKSTIVKQMKIIHEDGFSGEDVKQYKPVVYSNTIQSLAA .::::::::::::::::::::::::::::: XP_011 MKKLNPAGTTRRIIHEDGFSGEDVKQYKPVVYSNTIQSLAA 10 20 30 40 90 100 110 120 130 140 pF1KB3 IVRAMDTLGIEYGDKERKADAKMVCDVVSRMEDTEPFSAELLSAMMRLWGDSGIQECFNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IVRAMDTLGIEYGDKERKADAKMVCDVVSRMEDTEPFSAELLSAMMRLWGDSGIQECFNR 50 60 70 80 90 100 150 160 170 180 190 200 pF1KB3 SREYQLNDSAKYYLDSLDRIGAADYQPTEQDILRTRVKTTGIVETHFTFKNLHFRLFDVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SREYQLNDSAKYYLDSLDRIGAADYQPTEQDILRTRVKTTGIVETHFTFKNLHFRLFDVG 110 120 130 140 150 160 210 220 230 240 250 260 pF1KB3 GQRSERKKWIHCFEDVTAIIFCVALSGYDQVLHEDETTNRMHESLMLFDSICNNKFFIDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GQRSERKKWIHCFEDVTAIIFCVALSGYDQVLHEDETTNRMHESLMLFDSICNNKFFIDT 170 180 190 200 210 220 270 280 290 300 310 320 pF1KB3 SIILFLNKKDLFGEKIKKSPLTICFPEYTGPNTYEDAAAYIQAQFESKNRSPNKEIYCHM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SIILFLNKKDLFGEKIKKSPLTICFPEYTGPNTYEDAAAYIQAQFESKNRSPNKEIYCHM 230 240 250 260 270 280 330 340 350 pF1KB3 TCATDTNNIQVVFDAVTDIIIANNLRGCGLY ::::::::::::::::::::::::::::::: XP_011 TCATDTNNIQVVFDAVTDIIIANNLRGCGLY 290 300 310 >>NP_002060 (OMIM: 139310) guanine nucleotide-binding pr (354 aa) initn: 1520 init1: 1037 opt: 1691 Z-score: 2050.7 bits: 388.0 E(85289): 1.8e-107 Smith-Waterman score: 1691; 72.8% identity (86.8% similar) in 356 aa overlap (1-354:1-354) 10 20 30 40 50 60 pF1KB3 MGCTLSAEERAALERSKAIEKNLKEDGISAAKDVKLLLLGAGESGKSTIVKQMKIIHEDG ::::::::..::.:::: :..::.::: .::..::::::::::::::::::::::::: : NP_002 MGCTLSAEDKAAVERSKMIDRNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEAG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 FSGEDVKQYKPVVYSNTIQSLAAIVRAMDTLGIEYGDKERKADAKMVCDVVSRMEDTEPF .: :. :::: :::::::::. ::.::: : :..::. : ::... ... : : : NP_002 YSEEECKQYKAVVYSNTIQSIIAIIRAMGRLKIDFGDSARADDARQLFVLAGAAE--EGF 70 80 90 100 110 130 140 150 160 170 pF1KB3 -SAELLSAMMRLWGDSGIQECFNRSREYQLNDSAKYYLDSLDRIGAADYQPTEQDILRTR .::: ... ::: :::.: :::::::::::::: :::..::::. .: ::.::.:::: NP_002 MTAELAGVIKRLWKDSGVQACFNRSREYQLNDSAAYYLNDLDRIAQPNYIPTQQDVLRTR 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB3 VKTTGIVETHFTFKNLHFRLFDVGGQRSERKKWIHCFEDVTAIIFCVALSGYDQVLHEDE ::::::::::::::.:::..:::::::::::::::::: ::::::::::: :: :: ::: NP_002 VKTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDE 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB3 TTNRMHESLMLFDSICNNKFFIDTSIILFLNKKDLFGEKIKKSPLTICFPEYTGPNTYED ::::::. :::::::::.: :::::::::::::: :::::::::::.:::.: ::::. NP_002 EMNRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTICYPEYAGSNTYEE 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB3 AAAYIQAQFESKN-RSPNKEIYCHMTCATDTNNIQVVFDAVTDIIIANNLRGCGLY :::::: :::. : :. .:::: :.::::::.:.: :::::::.:: :::. :::. NP_002 AAAYIQCQFEDLNKRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF 300 310 320 330 340 350 >>NP_006487 (OMIM: 139370,602483) guanine nucleotide-bin (354 aa) initn: 1014 init1: 1014 opt: 1667 Z-score: 2021.6 bits: 382.6 E(85289): 7.2e-106 Smith-Waterman score: 1667; 71.3% identity (87.0% similar) in 355 aa overlap (1-354:1-354) 10 20 30 40 50 60 pF1KB3 MGCTLSAEERAALERSKAIEKNLKEDGISAAKDVKLLLLGAGESGKSTIVKQMKIIHEDG ::::::::..::.:::: :..::.::: .:::.::::::::::::::::::::::::::: NP_006 MGCTLSAEDKAAVERSKMIDRNLREDGEKAAKEVKLLLLGAGESGKSTIVKQMKIIHEDG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 FSGEDVKQYKPVVYSNTIQSLAAIVRAMDTLGIEYGDKERKADAKMVCDVVSRMEDTEPF .: .. :::: :::::::::. ::.::: : :..:. : ::... ... :. . NP_006 YSEDECKQYKVVVYSNTIQSIIAIIRAMGRLKIDFGEAARADDARQLFVLAGSAEEGV-M 70 80 90 100 110 130 140 150 160 170 180 pF1KB3 SAELLSAMMRLWGDSGIQECFNRSREYQLNDSAKYYLDSLDRIGAADYQPTEQDILRTRV . :: ... ::: :.:.: ::.:::::::::::.:::..::::. ..: ::.::.::::: NP_006 TPELAGVIKRLWRDGGVQACFSRSREYQLNDSASYYLNDLDRISQSNYIPTQQDVLRTRV 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB3 KTTGIVETHFTFKNLHFRLFDVGGQRSERKKWIHCFEDVTAIIFCVALSGYDQVLHEDET :::::::::::::.:.:..:::::::::::::::::: ::::::::::: :: :: ::: NP_006 KTTGIVETHFTFKDLYFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEE 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB3 TNRMHESLMLFDSICNNKFFIDTSIILFLNKKDLFGEKIKKSPLTICFPEYTGPNTYEDA ::::::. :::::::::.: .::::::::::::: ::::.::::::.::::: ::::.: NP_006 MNRMHESMKLFDSICNNKWFTETSIILFLNKKDLFEEKIKRSPLTICYPEYTGSNTYEEA 240 250 260 270 280 290 310 320 330 340 350 pF1KB3 AAYIQAQFESKNRSPN-KEIYCHMTCATDTNNIQVVFDAVTDIIIANNLRGCGLY ::::: :::. :: . :::: :.::::::.:.: :::::::.:: :::. :::: NP_006 AAYIQCQFEDLNRRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKECGLY 300 310 320 330 340 350 >>NP_002061 (OMIM: 139360,192605) guanine nucleotide-bin (355 aa) initn: 1641 init1: 1455 opt: 1646 Z-score: 1996.2 bits: 377.9 E(85289): 1.9e-104 Smith-Waterman score: 1646; 69.6% identity (86.2% similar) in 355 aa overlap (1-354:1-355) 10 20 30 40 50 60 pF1KB3 MGCTLSAEERAALERSKAIEKNLKEDGISAAKDVKLLLLGAGESGKSTIVKQMKIIHEDG ::::.:::..:: :::: :.:::.::: .::..::::::::::::::::::::::::::: NP_002 MGCTVSAEDKAAAERSKMIDKNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEDG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 FSGEDVKQYKPVVYSNTIQSLAAIVRAMDTLGIEYGDKERKADAKMVCDVVSRMEDTEPF .: :. .::. :::::::::. :::.:: .: :...: : ::... . :. . NP_002 YSEEECRQYRAVVYSNTIQSIMAIVKAMGNLQIDFADPSRADDARQLFALSCTAEEQGVL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 SAELLSAMMRLWGDSGIQECFNRSREYQLNDSAKYYLDSLDRIGAADYQPTEQDILRTRV .: ... :::.: :.: ::.::::::::::: :::..:.::. .:: ::.::.::::: NP_002 PDDLSGVIRRLWADHGVQACFGRSREYQLNDSAAYYLNDLERIAQSDYIPTQQDVLRTRV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 KTTGIVETHFTFKNLHFRLFDVGGQRSERKKWIHCFEDVTAIIFCVALSGYDQVLHEDET :::::::::::::.:::..:::::::::::::::::: :::::::::::.:: :: ::: NP_002 KTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSAYDLVLAEDEE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 TNRMHESLMLFDSICNNKFFIDTSIILFLNKKDLFGEKIKKSPLTICFPEYTGPNTYEDA ::::::. :::::::::.: :::::::::::::: ::: .:::::::::::: : :..: NP_002 MNRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKITHSPLTICFPEYTGANKYDEA 250 260 270 280 290 300 310 320 330 340 350 pF1KB3 AAYIQAQFESKN-RSPNKEIYCHMTCATDTNNIQVVFDAVTDIIIANNLRGCGLY :.:::..::. : :. .:::: :.::::::.:.: :::::::.:: :::. :::. NP_002 ASYIQSKFEDLNKRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF 310 320 330 340 350 >>NP_001095856 (OMIM: 139395) guanine nucleotide-binding (354 aa) initn: 1289 init1: 919 opt: 1470 Z-score: 1783.3 bits: 338.5 E(85289): 1.4e-92 Smith-Waterman score: 1470; 62.0% identity (82.8% similar) in 355 aa overlap (1-354:1-354) 10 20 30 40 50 60 pF1KB3 MGCTLSAEERAALERSKAIEKNLKEDGISAAKDVKLLLLGAGESGKSTIVKQMKIIHEDG :: .:.: . . .::: .::.:.::. :. ::::::::::::::::::::::::..: NP_001 MGSGISSESKESAKRSKELEKKLQEDAERDARTVKLLLLGAGESGKSTIVKQMKIIHKNG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 FSGEDVKQYKPVVYSNTIQSLAAIVRAMDTLGIEYGDKERKADAKMVCDVVSRMEDTEPF .: .. ..: :.::::.::. :::.:: ::::.: . . : ... ... .:: . NP_001 YSEQECMEFKAVIYSNTLQSILAIVKAMTTLGIDYVNPRSAEDQRQLYAMANTLEDG-GM 70 80 90 100 110 130 140 150 160 170 180 pF1KB3 SAELLSAMMRLWGDSGIQECFNRSREYQLNDSAKYYLDSLDRIGAADYQPTEQDILRTRV . .: .. ::: : ::: ::.:. :::::::: :::..:::: :. : :.:::.:..:: NP_001 TPQLAEVIKRLWRDPGIQACFERASEYQLNDSAAYYLNDLDRITASGYVPNEQDVLHSRV 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB3 KTTGIVETHFTFKNLHFRLFDVGGQRSERKKWIHCFEDVTAIIFCVALSGYDQVLHEDET :::::.::.:.::.::::.:::::::::::::::::: :: ::::.:::.::.:: ::: NP_001 KTTGIIETQFSFKDLHFRMFDVGGQRSERKKWIHCFEGVTCIIFCAALSAYDMVLVEDEE 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB3 TNRMHESLMLFDSICNNKFFIDTSIILFLNKKDLFGEKIKKSPLTICFPEYTGPNTYEDA .::::::: ::.::::.:.: :::.:::::::.: ::. : :.:::::::::::.::: NP_001 VNRMHESLHLFNSICNHKYFSTTSIVLFLNKKDIFQEKVTKVHLSICFPEYTGPNTFEDA 240 250 260 270 280 290 310 320 330 340 350 pF1KB3 AAYIQAQFESKN-RSPNKEIYCHMTCATDTNNIQVVFDAVTDIIIANNLRGCGLY . ::. :: . : .. .:::: ::::::::.:.. :::::::::: .::. :::. NP_001 GNYIKNQFLDLNLKKEDKEIYSHMTCATDTQNVKFVFDAVTDIIIKENLKDCGLF 300 310 320 330 340 350 >>NP_001159897 (OMIM: 139360,192605) guanine nucleotide- (318 aa) initn: 1463 init1: 1277 opt: 1468 Z-score: 1781.5 bits: 338.0 E(85289): 1.7e-92 Smith-Waterman score: 1468; 69.3% identity (85.4% similar) in 316 aa overlap (40-354:3-318) 10 20 30 40 50 60 pF1KB3 RAALERSKAIEKNLKEDGISAAKDVKLLLLGAGESGKSTIVKQMKIIHEDGFSGEDVKQY :::::::::::::::::::::.: :. .:: NP_001 MRGAGESGKSTIVKQMKIIHEDGYSEEECRQY 10 20 30 70 80 90 100 110 120 pF1KB3 KPVVYSNTIQSLAAIVRAMDTLGIEYGDKERKADAKMVCDVVSRMEDTEPFSAELLSAMM . :::::::::. :::.:: .: :...: : ::... . :. . .: ... NP_001 RAVVYSNTIQSIMAIVKAMGNLQIDFADPSRADDARQLFALSCTAEEQGVLPDDLSGVIR 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB3 RLWGDSGIQECFNRSREYQLNDSAKYYLDSLDRIGAADYQPTEQDILRTRVKTTGIVETH :::.: :.: ::.::::::::::: :::..:.::. .:: ::.::.:::::::::::::: NP_001 RLWADHGVQACFGRSREYQLNDSAAYYLNDLERIAQSDYIPTQQDVLRTRVKTTGIVETH 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB3 FTFKNLHFRLFDVGGQRSERKKWIHCFEDVTAIIFCVALSGYDQVLHEDETTNRMHESLM ::::.:::..:::::::::::::::::: :::::::::::.:: :: ::: ::::::. NP_001 FTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSAYDLVLAEDEEMNRMHESMK 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB3 LFDSICNNKFFIDTSIILFLNKKDLFGEKIKKSPLTICFPEYTGPNTYEDAAAYIQAQFE :::::::::.: :::::::::::::: ::: .:::::::::::: : :..::.:::..:: NP_001 LFDSICNNKWFTDTSIILFLNKKDLFEEKITHSPLTICFPEYTGANKYDEAASYIQSKFE 220 230 240 250 260 270 310 320 330 340 350 pF1KB3 SKN-RSPNKEIYCHMTCATDTNNIQVVFDAVTDIIIANNLRGCGLY . : :. .:::: :.::::::.:.: :::::::.:: :::. :::. NP_001 DLNKRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF 280 290 300 310 >>NP_001269548 (OMIM: 139360,192605) guanine nucleotide- (339 aa) initn: 1463 init1: 1277 opt: 1468 Z-score: 1781.1 bits: 338.0 E(85289): 1.8e-92 Smith-Waterman score: 1468; 69.3% identity (85.4% similar) in 316 aa overlap (40-354:24-339) 10 20 30 40 50 60 pF1KB3 RAALERSKAIEKNLKEDGISAAKDVKLLLLGAGESGKSTIVKQMKIIHEDGFSGEDVKQY :::::::::::::::::::::.: :. .:: NP_001 MEYAGHLPASSAQGTILACTSCTGAGESGKSTIVKQMKIIHEDGYSEEECRQY 10 20 30 40 50 70 80 90 100 110 120 pF1KB3 KPVVYSNTIQSLAAIVRAMDTLGIEYGDKERKADAKMVCDVVSRMEDTEPFSAELLSAMM . :::::::::. :::.:: .: :...: : ::... . :. . .: ... NP_001 RAVVYSNTIQSIMAIVKAMGNLQIDFADPSRADDARQLFALSCTAEEQGVLPDDLSGVIR 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB3 RLWGDSGIQECFNRSREYQLNDSAKYYLDSLDRIGAADYQPTEQDILRTRVKTTGIVETH :::.: :.: ::.::::::::::: :::..:.::. .:: ::.::.:::::::::::::: NP_001 RLWADHGVQACFGRSREYQLNDSAAYYLNDLERIAQSDYIPTQQDVLRTRVKTTGIVETH 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB3 FTFKNLHFRLFDVGGQRSERKKWIHCFEDVTAIIFCVALSGYDQVLHEDETTNRMHESLM ::::.:::..:::::::::::::::::: :::::::::::.:: :: ::: ::::::. NP_001 FTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSAYDLVLAEDEEMNRMHESMK 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB3 LFDSICNNKFFIDTSIILFLNKKDLFGEKIKKSPLTICFPEYTGPNTYEDAAAYIQAQFE :::::::::.: :::::::::::::: ::: .:::::::::::: : :..::.:::..:: NP_001 LFDSICNNKWFTDTSIILFLNKKDLFEEKITHSPLTICFPEYTGANKYDEAASYIQSKFE 240 250 260 270 280 290 310 320 330 340 350 pF1KB3 SKN-RSPNKEIYCHMTCATDTNNIQVVFDAVTDIIIANNLRGCGLY . : :. .:::: :.::::::.:.: :::::::.:: :::. :::. NP_001 DLNKRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF 300 310 320 330 >>NP_001269549 (OMIM: 139360,192605) guanine nucleotide- (339 aa) initn: 1463 init1: 1277 opt: 1468 Z-score: 1781.1 bits: 338.0 E(85289): 1.8e-92 Smith-Waterman score: 1468; 69.3% identity (85.4% similar) in 316 aa overlap (40-354:24-339) 10 20 30 40 50 60 pF1KB3 RAALERSKAIEKNLKEDGISAAKDVKLLLLGAGESGKSTIVKQMKIIHEDGFSGEDVKQY :::::::::::::::::::::.: :. .:: NP_001 MTEGVKTLGWTKQKGGCHWGRSEGAGESGKSTIVKQMKIIHEDGYSEEECRQY 10 20 30 40 50 70 80 90 100 110 120 pF1KB3 KPVVYSNTIQSLAAIVRAMDTLGIEYGDKERKADAKMVCDVVSRMEDTEPFSAELLSAMM . :::::::::. :::.:: .: :...: : ::... . :. . .: ... NP_001 RAVVYSNTIQSIMAIVKAMGNLQIDFADPSRADDARQLFALSCTAEEQGVLPDDLSGVIR 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB3 RLWGDSGIQECFNRSREYQLNDSAKYYLDSLDRIGAADYQPTEQDILRTRVKTTGIVETH :::.: :.: ::.::::::::::: :::..:.::. .:: ::.::.:::::::::::::: NP_001 RLWADHGVQACFGRSREYQLNDSAAYYLNDLERIAQSDYIPTQQDVLRTRVKTTGIVETH 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB3 FTFKNLHFRLFDVGGQRSERKKWIHCFEDVTAIIFCVALSGYDQVLHEDETTNRMHESLM ::::.:::..:::::::::::::::::: :::::::::::.:: :: ::: ::::::. NP_001 FTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSAYDLVLAEDEEMNRMHESMK 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB3 LFDSICNNKFFIDTSIILFLNKKDLFGEKIKKSPLTICFPEYTGPNTYEDAAAYIQAQFE :::::::::.: :::::::::::::: ::: .:::::::::::: : :..::.:::..:: NP_001 LFDSICNNKWFTDTSIILFLNKKDLFEEKITHSPLTICFPEYTGANKYDEAASYIQSKFE 240 250 260 270 280 290 310 320 330 340 350 pF1KB3 SKN-RSPNKEIYCHMTCATDTNNIQVVFDAVTDIIIANNLRGCGLY . : :. .:::: :.::::::.:.: :::::::.:: :::. :::. NP_001 DLNKRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF 300 310 320 330 354 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 02:41:24 2016 done: Fri Nov 4 02:41:25 2016 Total Scan time: 7.110 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]