FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3889, 808 aa 1>>>pF1KB3889 808 - 808 aa - 808 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.2781+/-0.00116; mu= 10.1758+/- 0.068 mean_var=150.2546+/-32.891, 0's: 0 Z-trim(106.2): 193 B-trim: 78 in 1/50 Lambda= 0.104631 statistics sampled from 8615 (8857) to 8615 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.631), E-opt: 0.2 (0.272), width: 16 Scan time: 3.730 The best scores are: opt bits E(32554) CCDS10453.1 TBL3 gene_id:10607|Hs108|chr16 ( 808) 5416 830.7 0 CCDS898.1 WDR3 gene_id:10885|Hs108|chr1 ( 943) 363 68.0 8.5e-11 >>CCDS10453.1 TBL3 gene_id:10607|Hs108|chr16 (808 aa) initn: 5416 init1: 5416 opt: 5416 Z-score: 4430.5 bits: 830.7 E(32554): 0 Smith-Waterman score: 5416; 99.8% identity (99.9% similar) in 808 aa overlap (1-808:1-808) 10 20 30 40 50 60 pF1KB3 MAETAAGVGRFKTNYAVERKIEPFYKGGKAQLDQTGQHLFCVCGTRVNILEVASGAVLRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 MAETAAGVGRFKTNYAVERKIEPFYKGGKAQLDQTGQHLFCVCGTRVNILEVASGAVLRS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 LEQEDQEDITAFDLSPDNEVLVTASRALLLAQWAWQEGSVTRLWKAIHTAPVATMAFDPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 LEQEDQEDITAFDLSPDNEVLVTASRALLLAQWAWQEGSVTRLWKAIHTAPVATMAFDPT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 STLLATGGCDGAVRVWDIVRHYGTHHFRGSPGVVHLVAFHPDPTRLLLFSSATDAAIRVW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 STLLATGGCDGAVRVWDIVRHYGTHHFRGSPGVVHLVAFHPDPTRLLLFSSATDAAIRVW 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 SLQDRSCLAVLTAHYSAVTSLAFSADGHTMLSSGRDKICIIWDLQSCQATRTVPVFESVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 SLQDRSCLAVLTAHYSAVTSLAFSADGHTMLSSGRDKICIIWDLQSCQATRTVPVFESVE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 AAVLLPEEPVSQLGVKSPGLYFLTAGDQGTLRVWEAASGQCVYTQAQPPGPGRELTHCTL ::::::::::::::::::::::::::::::::::::::::::::::::::::.::::::: CCDS10 AAVLLPEEPVSQLGVKSPGLYFLTAGDQGTLRVWEAASGQCVYTQAQPPGPGQELTHCTL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 AHTAGVVLTATADHNLLLYEARSLRLQKQFAGYSEEVLDVRFLGPEDSHVVVASNSPCLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 AHTAGVVLTATADHNLLLYEARSLRLQKQFAGYSEEVLDVRFLGPEDSHVVVASNSPCLK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 VFELQTSACQILHGHTDIVLALDVFRKGWLFASCAKDQSVRIWRMNKAGQVMCVAQGSGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 VFELQTSACQILHGHTDIVLALDVFRKGWLFASCAKDQSVRIWRMNKAGQVMCVAQGSGH 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 THSVGTVCCSRLKESFLVTGSQDCTVKLWPLPKALLPKNTAPDNGPILLQAQTTQRCHDK :::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::: CCDS10 THSVGTVCCSRLKESFLVTGSQDCTVKLWPLPKALLSKNTAPDNGPILLQAQTTQRCHDK 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 DINSVAIAPNDKLLATGSQDRTAKLWALPQCQLLGVFSGHRRGLWCVQFSPMDQVLATAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 DINSVAIAPNDKLLATGSQDRTAKLWALPQCQLLGVFSGHRRGLWCVQFSPMDQVLATAS 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 ADGTIKLWALQDFSCLKTFEGHDASVLKVAFVSRGTQLLSSGSDGLVKLWTIKNNECVRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 ADGTIKLWALQDFSCLKTFEGHDASVLKVAFVSRGTQLLSSGSDGLVKLWTIKNNECVRT 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 LDAHEDKVWGLHCSRLDDHALTGASDSRVILWKDVTEAEQAEEQARQEEQVVRQQELDNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 LDAHEDKVWGLHCSRLDDHALTGASDSRVILWKDVTEAEQAEEQARQEEQVVRQQELDNL 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB3 LHEKRYLRALGLAISLDRPHTVLTVIQAIRRDPEACEKLEATMLRLRRDQKEALLRFCVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 LHEKRYLRALGLAISLDRPHTVLTVIQAIRRDPEACEKLEATMLRLRRDQKEALLRFCVT 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB3 WNTNSRHCHEAQAVLGVLLRREAPEELLAYEGVRAALEALLPYTERHFQRLSRTLQAAAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 WNTNSRHCHEAQAVLGVLLRREAPEELLAYEGVRAALEALLPYTERHFQRLSRTLQAAAF 730 740 750 760 770 780 790 800 pF1KB3 LDFLWHNMKLPVPAAAPTPWETHKGALP :::::::::::::::::::::::::::: CCDS10 LDFLWHNMKLPVPAAAPTPWETHKGALP 790 800 >>CCDS898.1 WDR3 gene_id:10885|Hs108|chr1 (943 aa) initn: 558 init1: 327 opt: 363 Z-score: 307.3 bits: 68.0 E(32554): 8.5e-11 Smith-Waterman score: 448; 21.9% identity (52.3% similar) in 702 aa overlap (57-656:60-732) 30 40 50 60 70 80 pF1KB3 GGKAQLDQTGQHLFCVCGTRVNILEVASGAVLRSLEQEDQEDITAFDLSPDNEVLVTASR .:..:.:: .: . :::. :... . CCDS89 TLRGEKGRYVAVPACEHVFIWDLRKGEKILILQGLKQE----VTCLCPSPDGLHLAVGYE 30 40 50 60 70 80 90 100 110 120 130 140 pF1KB3 --ALLLAQWAWQEGSVTRLWKAIHTAPVATMAFDPTSTLLATGGCDGAVRVWDIVRHYGT .. . . ::.:: : : ..:. .: . ::.:. : . :::.. . : CCDS89 DGSIRIFSLLSGEGNVTF---NGHKAAITTLKYDQLGGRLASGSKDTDIIVWDVINESGL 90 100 110 120 130 140 150 160 170 180 190 200 pF1KB3 HHFRGSPGVVHLVAFHPDPTRLLLFSSATDAAIRVWSLQDRSCLAVLTAHYSAVTSLAFS ....: .. . : . . :: .:. :. .. :.:. . :. ....: . : .:.. CCDS89 YRLKGHKDAITQALFLREKN--LLVTSGKDTMVKWWDLDTQHCFKTMVGHRTEVWGLVLL 150 160 170 180 190 200 210 220 230 240 250 260 pF1KB3 ADGHTMLSSGRDKICIIWDLQSCQATRTVPVFESVEAAVLLPEEP-VSQLGVKSPGLYFL .. . ..... :. .:: . .. .: :::: ... .:::. CCDS89 SEEKRLITGASDSELRVWD---------IAYLQEIED----PEEPDPKKIKGSSPGIQDT 210 220 230 240 270 280 290 300 310 320 pF1KB3 TAGDQGTLRVWEAASGQCVYTQAQPP--GPGRE-LTHCTLAHTAGVVLTATADHNLLLYE ...:.... :: . . . ::. ... .. .:. .. .: : :. CCDS89 LEAEDGAFETDEAPEDRILSCRKAGSIMREGRDRVVNLAVDKTGRILACHGTDSVLELFC 250 260 270 280 290 300 330 340 pF1KB3 ARSLR-LQKQF----------------AGYSEE---------------VLDVRFLGPEDS : . .::.. : :. : ... . : CCDS89 ILSKKEIQKKMDKKMKKARKKAKLHSSKGEEEDPEVNVEMSLQDEIQRVTNIKTSAKIKS 310 320 330 340 350 360 350 360 370 380 pF1KB3 HVVVASNSPCLK-VFELQTSACQI-------------------LHGHTDIVLALDVFRKG .. : :: :: ::.. .. . :: . : .:. . CCDS89 FDLIHSPHGELKAVFLLQNNLVELYSLNPSLPTPQPVRTSRITIGGHRSDVRTLSFSSDN 370 380 390 400 410 420 390 400 410 pF1KB3 WLFASCAKDQSVRIWRMN-----------------------------KAGQVMCVAQGSG : : : :..:: . :.:... .:: CCDS89 IAVLSAAAD-SIKIWNRSTLQCIRTMTCEYALCSFFVPGDRQVVIGTKTGKLQLYDLASG 430 440 450 460 470 480 420 430 440 450 460 470 pF1KB3 --------HTHSVGTVCCSRLKESFLVTGSQDCTVKLWPLPKALLPKNTAPDNGPILLQA : .. .. : ...: :::. : .::.: . :. ... .. . :. CCDS89 NLLETIDAHDGALWSMSLSPDQRGF-VTGGADKSVKFWDF--ELVKDENSTQKRLSVKQT 490 500 510 520 530 540 480 490 500 510 520 530 pF1KB3 QTTQRCHDKDINSVAIAPNDKLLATGSQDRTAKLWALPQCQLLGVFSGHRRGLWCVQFSP .: : :.:. :. .::.::::.. : :.:.. . ... . ::. . :...: CCDS89 RTLQ--LDEDVLCVSYSPNQKLLAVSLLDCTVKIFYVDTLKFFLSLYGHKLPVICMDISH 550 560 570 580 590 600 540 550 560 570 580 590 pF1KB3 MDQVLATASADGTIKLWALQDFS-CLKTFEGHDASVLKVAFVSRGTQLLSSGSDGLVKLW ..::.::: ..:.:.: ::. : :.. .:: ::. . :: .. ....:.: .: : CCDS89 DGALIATGSADRNVKIWGL-DFGDCHKSLFAHDDSVMYLQFVPKSHLFFTAGKDHKIKQW 610 620 630 640 650 660 600 610 620 630 640 pF1KB3 TIKNNECVRTLDAHEDKVWGLHCSRLDDHALTGASDSRVILWKD------VTEAEQAEEQ . : ..::..:....: : : :...... :. . ::. . : .. :.. CCDS89 DADKFEHIQTLEGHHQEIWCLAVSPSGDYVVSSSHDKSLRLWERTREPLILEEEREMERE 670 680 690 700 710 720 650 660 670 680 690 700 pF1KB3 ARQEEQVVRQQELDNLLHEKRYLRALGLAISLDRPHTVLTVIQAIRRDPEACEKLEATML :. ::.:..... CCDS89 AEYEESVAKEDQPAVPGETQGDSYFTGKKTIETVKAAERIMEAIELYREETAKMKEHKAI 730 740 750 760 770 780 808 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 14:07:58 2016 done: Thu Nov 3 14:07:59 2016 Total Scan time: 3.730 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]