FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3906, 418 aa 1>>>pF1KB3906 418 - 418 aa - 418 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.7200+/-0.000392; mu= 17.8184+/- 0.025 mean_var=123.0669+/-26.070, 0's: 0 Z-trim(114.9): 14 B-trim: 805 in 1/57 Lambda= 0.115612 statistics sampled from 25012 (25026) to 25012 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.651), E-opt: 0.2 (0.293), width: 16 Scan time: 8.820 The best scores are: opt bits E(85289) NP_620128 (OMIM: 610826,616505) solute carrier fam ( 418) 2803 478.8 1.1e-134 NP_001290179 (OMIM: 610826,616505) solute carrier ( 327) 2116 364.1 2.9e-100 NP_001290178 (OMIM: 610826,616505) solute carrier ( 337) 1578 274.4 3e-73 >>NP_620128 (OMIM: 610826,616505) solute carrier family (418 aa) initn: 2803 init1: 2803 opt: 2803 Z-score: 2539.1 bits: 478.8 E(85289): 1.1e-134 Smith-Waterman score: 2803; 100.0% identity (100.0% similar) in 418 aa overlap (1-418:1-418) 10 20 30 40 50 60 pF1KB3 MHPRRPDGFDGLGYRGGARDEQGFGGAFPARSFSTGSDLGHWVTTPPDIPGSRNLHWGEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_620 MHPRRPDGFDGLGYRGGARDEQGFGGAFPARSFSTGSDLGHWVTTPPDIPGSRNLHWGEK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 SPPYGVPTTSTPYEGPTEEPFSSGGGGSVQGQSSEQLNRFAGFGIGLASLFTENVLAHPC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_620 SPPYGVPTTSTPYEGPTEEPFSSGGGGSVQGQSSEQLNRFAGFGIGLASLFTENVLAHPC 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 IVLRRQCQVNYHAQHYHLTPFTVINIMYSFNKTQGPRALWKGMGSTFIVQGVTLGAEGII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_620 IVLRRQCQVNYHAQHYHLTPFTVINIMYSFNKTQGPRALWKGMGSTFIVQGVTLGAEGII 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 SEFTPLPREVLHKWSPKQIGEHLLLKSLTYVVAMPFYSASLIETVQSEIIRDNTGILECV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_620 SEFTPLPREVLHKWSPKQIGEHLLLKSLTYVVAMPFYSASLIETVQSEIIRDNTGILECV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 KEGIGRVIGMGVPHSKRLLPLLSLIFPTVLHGVLHYIISSVIQKFVLLILKRKTYNSHLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_620 KEGIGRVIGMGVPHSKRLLPLLSLIFPTVLHGVLHYIISSVIQKFVLLILKRKTYNSHLA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 ESTSPVQSMLDAYFPELIANFAASLCSDVILYPLETVLHRLHIQGTRTIIDNTDLGYEVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_620 ESTSPVQSMLDAYFPELIANFAASLCSDVILYPLETVLHRLHIQGTRTIIDNTDLGYEVL 310 320 330 340 350 360 370 380 390 400 410 pF1KB3 PINTQYEGMRDCINTIRQEEGVFGFYKGFGAVIIQYTLHAAVLQITKIIYSTLLQNNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_620 PINTQYEGMRDCINTIRQEEGVFGFYKGFGAVIIQYTLHAAVLQITKIIYSTLLQNNI 370 380 390 400 410 >>NP_001290179 (OMIM: 610826,616505) solute carrier fami (327 aa) initn: 2116 init1: 2116 opt: 2116 Z-score: 1921.1 bits: 364.1 E(85289): 2.9e-100 Smith-Waterman score: 2116; 99.7% identity (100.0% similar) in 325 aa overlap (94-418:3-327) 70 80 90 100 110 120 pF1KB3 YGVPTTSTPYEGPTEEPFSSGGGGSVQGQSSEQLNRFAGFGIGLASLFTENVLAHPCIVL .::::::::::::::::::::::::::::: NP_001 MKTEQLNRFAGFGIGLASLFTENVLAHPCIVL 10 20 30 130 140 150 160 170 180 pF1KB3 RRQCQVNYHAQHYHLTPFTVINIMYSFNKTQGPRALWKGMGSTFIVQGVTLGAEGIISEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RRQCQVNYHAQHYHLTPFTVINIMYSFNKTQGPRALWKGMGSTFIVQGVTLGAEGIISEF 40 50 60 70 80 90 190 200 210 220 230 240 pF1KB3 TPLPREVLHKWSPKQIGEHLLLKSLTYVVAMPFYSASLIETVQSEIIRDNTGILECVKEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TPLPREVLHKWSPKQIGEHLLLKSLTYVVAMPFYSASLIETVQSEIIRDNTGILECVKEG 100 110 120 130 140 150 250 260 270 280 290 300 pF1KB3 IGRVIGMGVPHSKRLLPLLSLIFPTVLHGVLHYIISSVIQKFVLLILKRKTYNSHLAEST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IGRVIGMGVPHSKRLLPLLSLIFPTVLHGVLHYIISSVIQKFVLLILKRKTYNSHLAEST 160 170 180 190 200 210 310 320 330 340 350 360 pF1KB3 SPVQSMLDAYFPELIANFAASLCSDVILYPLETVLHRLHIQGTRTIIDNTDLGYEVLPIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SPVQSMLDAYFPELIANFAASLCSDVILYPLETVLHRLHIQGTRTIIDNTDLGYEVLPIN 220 230 240 250 260 270 370 380 390 400 410 pF1KB3 TQYEGMRDCINTIRQEEGVFGFYKGFGAVIIQYTLHAAVLQITKIIYSTLLQNNI ::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TQYEGMRDCINTIRQEEGVFGFYKGFGAVIIQYTLHAAVLQITKIIYSTLLQNNI 280 290 300 310 320 >>NP_001290178 (OMIM: 610826,616505) solute carrier fami (337 aa) initn: 1578 init1: 1578 opt: 1578 Z-score: 1435.9 bits: 274.4 E(85289): 3e-73 Smith-Waterman score: 2118; 80.6% identity (80.6% similar) in 418 aa overlap (1-418:1-337) 10 20 30 40 50 60 pF1KB3 MHPRRPDGFDGLGYRGGARDEQGFGGAFPARSFSTGSDLGHWVTTPPDIPGSRNLHWGEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MHPRRPDGFDGLGYRGGARDEQGFGGAFPARSFSTGSDLGHWVTTPPDIPGSRNLHWGEK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 SPPYGVPTTSTPYEGPTEEPFSSGGGGSVQGQSSEQLNRFAGFGIGLASLFTENVLAHPC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SPPYGVPTTSTPYEGPTEEPFSSGGGGSVQGQSSEQLNRFAGFGIGLASLFTENVLAHPC 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 IVLRRQCQVNYHAQHYHLTPFTVINIMYSFNKTQGPRALWKGMGSTFIVQGVTLGAEGII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IVLRRQCQVNYHAQHYHLTPFTVINIMYSFNKTQGPRALWKGMGSTFIVQGVTLGAEGII 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 SEFTPLPREVLHKWSPKQIGEHLLLKSLTYVVAMPFYSASLIETVQSEIIRDNTGILECV ::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SEFTPLPREVLHKWSPKQIGEHLLLKSLTYVVAMPFYSASLIETVQS------------- 190 200 210 220 250 260 270 280 290 300 pF1KB3 KEGIGRVIGMGVPHSKRLLPLLSLIFPTVLHGVLHYIISSVIQKFVLLILKRKTYNSHLA NP_001 ------------------------------------------------------------ 310 320 330 340 350 360 pF1KB3 ESTSPVQSMLDAYFPELIANFAASLCSDVILYPLETVLHRLHIQGTRTIIDNTDLGYEVL :::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 --------MLDAYFPELIANFAASLCSDVILYPLETVLHRLHIQGTRTIIDNTDLGYEVL 230 240 250 260 270 370 380 390 400 410 pF1KB3 PINTQYEGMRDCINTIRQEEGVFGFYKGFGAVIIQYTLHAAVLQITKIIYSTLLQNNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PINTQYEGMRDCINTIRQEEGVFGFYKGFGAVIIQYTLHAAVLQITKIIYSTLLQNNI 280 290 300 310 320 330 418 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 05:26:28 2016 done: Sat Nov 5 05:26:29 2016 Total Scan time: 8.820 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]