FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3911, 454 aa 1>>>pF1KB3911 454 - 454 aa - 454 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.7506+/-0.000464; mu= 15.6401+/- 0.029 mean_var=75.6947+/-15.654, 0's: 0 Z-trim(110.2): 156 B-trim: 583 in 1/51 Lambda= 0.147415 statistics sampled from 18289 (18461) to 18289 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.574), E-opt: 0.2 (0.216), width: 16 Scan time: 7.070 The best scores are: opt bits E(85289) XP_005260995 (OMIM: 600609) PREDICTED: GA-binding ( 454) 2977 643.0 4.8e-184 NP_002031 (OMIM: 600609) GA-binding protein alpha ( 454) 2977 643.0 4.8e-184 XP_011527823 (OMIM: 600609) PREDICTED: GA-binding ( 454) 2977 643.0 4.8e-184 XP_016883802 (OMIM: 600609) PREDICTED: GA-binding ( 454) 2977 643.0 4.8e-184 NP_001184226 (OMIM: 600609) GA-binding protein alp ( 454) 2977 643.0 4.8e-184 XP_011527822 (OMIM: 600609) PREDICTED: GA-binding ( 454) 2977 643.0 4.8e-184 XP_016883778 (OMIM: 165080) PREDICTED: transcripti ( 428) 600 137.5 6.8e-32 XP_011527788 (OMIM: 165080) PREDICTED: transcripti ( 435) 600 137.5 6.9e-32 NP_001317380 (OMIM: 164720) protein C-ets-1 isofor ( 354) 473 110.4 7.9e-24 XP_016872806 (OMIM: 164720) PREDICTED: protein C-e ( 398) 473 110.5 8.7e-24 XP_011540953 (OMIM: 164720) PREDICTED: protein C-e ( 432) 473 110.5 9.3e-24 NP_001155894 (OMIM: 164720) protein C-ets-1 isofor ( 225) 468 109.3 1.1e-23 XP_016872805 (OMIM: 164720) PREDICTED: protein C-e ( 418) 468 109.4 1.9e-23 NP_005229 (OMIM: 164720) protein C-ets-1 isoform 2 ( 441) 468 109.4 2e-23 XP_016872804 (OMIM: 164720) PREDICTED: protein C-e ( 450) 468 109.4 2e-23 XP_011540952 (OMIM: 164720) PREDICTED: protein C-e ( 475) 468 109.4 2.1e-23 XP_016872803 (OMIM: 164720) PREDICTED: protein C-e ( 485) 468 109.4 2.1e-23 NP_001137292 (OMIM: 164720) protein C-ets-1 isofor ( 485) 468 109.4 2.1e-23 XP_011540951 (OMIM: 164720) PREDICTED: protein C-e ( 519) 468 109.4 2.3e-23 XP_016883779 (OMIM: 164740) PREDICTED: protein C-e ( 469) 457 107.1 1.1e-22 NP_005230 (OMIM: 164740) protein C-ets-2 isoform 1 ( 469) 457 107.1 1.1e-22 XP_005260992 (OMIM: 164740) PREDICTED: protein C-e ( 469) 457 107.1 1.1e-22 NP_001243224 (OMIM: 164740) protein C-ets-2 isofor ( 609) 457 107.1 1.3e-22 NP_059991 (OMIM: 607150) protein FEV [Homo sapiens ( 238) 406 96.1 1.1e-19 NP_001230358 (OMIM: 165080) transcriptional regula ( 363) 408 96.6 1.2e-19 NP_001129627 (OMIM: 165080) transcriptional regula ( 387) 408 96.6 1.2e-19 NP_001317954 (OMIM: 165080) transcriptional regula ( 455) 408 96.7 1.4e-19 XP_016883776 (OMIM: 165080) PREDICTED: transcripti ( 459) 408 96.7 1.4e-19 NP_004440 (OMIM: 165080) transcriptional regulator ( 462) 408 96.7 1.4e-19 NP_891548 (OMIM: 165080) transcriptional regulator ( 479) 408 96.7 1.5e-19 NP_001129626 (OMIM: 165080) transcriptional regula ( 486) 408 96.7 1.5e-19 NP_001230357 (OMIM: 165080) transcriptional regula ( 486) 408 96.7 1.5e-19 NP_001257941 (OMIM: 193067) Friend leukemia integr ( 259) 400 94.8 2.8e-19 XP_011541004 (OMIM: 193067) PREDICTED: Friend leuk ( 410) 402 95.4 3.1e-19 NP_001257939 (OMIM: 193067) Friend leukemia integr ( 386) 400 94.9 4e-19 XP_016872895 (OMIM: 193067) PREDICTED: Friend leuk ( 419) 400 94.9 4.3e-19 XP_016872894 (OMIM: 193067) PREDICTED: Friend leuk ( 419) 400 94.9 4.3e-19 NP_001161153 (OMIM: 193067) Friend leukemia integr ( 419) 400 94.9 4.3e-19 XP_011541003 (OMIM: 193067) PREDICTED: Friend leuk ( 419) 400 94.9 4.3e-19 NP_002008 (OMIM: 193067) Friend leukemia integrati ( 452) 400 95.0 4.6e-19 NP_001156624 (OMIM: 600541) ETS translocation vari ( 374) 369 88.3 3.7e-17 NP_001156623 (OMIM: 600541) ETS translocation vari ( 419) 369 88.3 4.1e-17 NP_001156622 (OMIM: 600541) ETS translocation vari ( 437) 369 88.4 4.3e-17 NP_001156619 (OMIM: 600541) ETS translocation vari ( 454) 369 88.4 4.4e-17 NP_001156620 (OMIM: 600541) ETS translocation vari ( 459) 369 88.4 4.5e-17 NP_001156621 (OMIM: 600541) ETS translocation vari ( 459) 369 88.4 4.5e-17 XP_011513472 (OMIM: 600541) PREDICTED: ETS translo ( 472) 369 88.4 4.6e-17 XP_005249693 (OMIM: 600541) PREDICTED: ETS translo ( 477) 369 88.4 4.6e-17 XP_005249692 (OMIM: 600541) PREDICTED: ETS translo ( 477) 369 88.4 4.6e-17 NP_004947 (OMIM: 600541) ETS translocation variant ( 477) 369 88.4 4.6e-17 >>XP_005260995 (OMIM: 600609) PREDICTED: GA-binding prot (454 aa) initn: 2977 init1: 2977 opt: 2977 Z-score: 3425.2 bits: 643.0 E(85289): 4.8e-184 Smith-Waterman score: 2977; 100.0% identity (100.0% similar) in 454 aa overlap (1-454:1-454) 10 20 30 40 50 60 pF1KB3 MTKREAEELIEIEIDGTEKAECTEESIVEQTYAPAECVSQAIDINEPIGNLKKLLEPRLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MTKREAEELIEIEIDGTEKAECTEESIVEQTYAPAECVSQAIDINEPIGNLKKLLEPRLQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 CSLDAHEICLQDIQLDPERSLFDQGVKTDGTVQLSVQVISYQGIEPKLNILEIVKPADTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 CSLDAHEICLQDIQLDPERSLFDQGVKTDGTVQLSVQVISYQGIEPKLNILEIVKPADTV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 EVVIDPDAHHAESEAHLVEEAQVITLDGTKHITTISDETSEQVTRWAAALEGYRKEQERL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EVVIDPDAHHAESEAHLVEEAQVITLDGTKHITTISDETSEQVTRWAAALEGYRKEQERL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 GIPYDPIQWSTDQVLHWVVWVMKEFSMTDIDLTTLNISGRELCSLNQEDFFQRVPRGEIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GIPYDPIQWSTDQVLHWVVWVMKEFSMTDIDLTTLNISGRELCSLNQEDFFQRVPRGEIL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 WSHLELLRKYVLASQEQQMNEIVTIDQPVQIIPASVQSATPTTIKVINSSAKAAKVQRAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 WSHLELLRKYVLASQEQQMNEIVTIDQPVQIIPASVQSATPTTIKVINSSAKAAKVQRAP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 RISGEDRSSPGNRTGNNGQIQLWQFLLELLTDKDARDCISWVGDEGEFKLNQPELVAQKW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RISGEDRSSPGNRTGNNGQIQLWQFLLELLTDKDARDCISWVGDEGEFKLNQPELVAQKW 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 GQRKNKPTMNYEKLSRALRYYYDGDMICKVQGKRFVYKFVCDLKTLIGYSAAELNRLVTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GQRKNKPTMNYEKLSRALRYYYDGDMICKVQGKRFVYKFVCDLKTLIGYSAAELNRLVTE 370 380 390 400 410 420 430 440 450 pF1KB3 CEQKKLAKMQLHGIAQPVTAVALATASLQTEKDN :::::::::::::::::::::::::::::::::: XP_005 CEQKKLAKMQLHGIAQPVTAVALATASLQTEKDN 430 440 450 >>NP_002031 (OMIM: 600609) GA-binding protein alpha chai (454 aa) initn: 2977 init1: 2977 opt: 2977 Z-score: 3425.2 bits: 643.0 E(85289): 4.8e-184 Smith-Waterman score: 2977; 100.0% identity (100.0% similar) in 454 aa overlap (1-454:1-454) 10 20 30 40 50 60 pF1KB3 MTKREAEELIEIEIDGTEKAECTEESIVEQTYAPAECVSQAIDINEPIGNLKKLLEPRLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MTKREAEELIEIEIDGTEKAECTEESIVEQTYAPAECVSQAIDINEPIGNLKKLLEPRLQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 CSLDAHEICLQDIQLDPERSLFDQGVKTDGTVQLSVQVISYQGIEPKLNILEIVKPADTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 CSLDAHEICLQDIQLDPERSLFDQGVKTDGTVQLSVQVISYQGIEPKLNILEIVKPADTV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 EVVIDPDAHHAESEAHLVEEAQVITLDGTKHITTISDETSEQVTRWAAALEGYRKEQERL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 EVVIDPDAHHAESEAHLVEEAQVITLDGTKHITTISDETSEQVTRWAAALEGYRKEQERL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 GIPYDPIQWSTDQVLHWVVWVMKEFSMTDIDLTTLNISGRELCSLNQEDFFQRVPRGEIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 GIPYDPIQWSTDQVLHWVVWVMKEFSMTDIDLTTLNISGRELCSLNQEDFFQRVPRGEIL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 WSHLELLRKYVLASQEQQMNEIVTIDQPVQIIPASVQSATPTTIKVINSSAKAAKVQRAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 WSHLELLRKYVLASQEQQMNEIVTIDQPVQIIPASVQSATPTTIKVINSSAKAAKVQRAP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 RISGEDRSSPGNRTGNNGQIQLWQFLLELLTDKDARDCISWVGDEGEFKLNQPELVAQKW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 RISGEDRSSPGNRTGNNGQIQLWQFLLELLTDKDARDCISWVGDEGEFKLNQPELVAQKW 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 GQRKNKPTMNYEKLSRALRYYYDGDMICKVQGKRFVYKFVCDLKTLIGYSAAELNRLVTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 GQRKNKPTMNYEKLSRALRYYYDGDMICKVQGKRFVYKFVCDLKTLIGYSAAELNRLVTE 370 380 390 400 410 420 430 440 450 pF1KB3 CEQKKLAKMQLHGIAQPVTAVALATASLQTEKDN :::::::::::::::::::::::::::::::::: NP_002 CEQKKLAKMQLHGIAQPVTAVALATASLQTEKDN 430 440 450 >>XP_011527823 (OMIM: 600609) PREDICTED: GA-binding prot (454 aa) initn: 2977 init1: 2977 opt: 2977 Z-score: 3425.2 bits: 643.0 E(85289): 4.8e-184 Smith-Waterman score: 2977; 100.0% identity (100.0% similar) in 454 aa overlap (1-454:1-454) 10 20 30 40 50 60 pF1KB3 MTKREAEELIEIEIDGTEKAECTEESIVEQTYAPAECVSQAIDINEPIGNLKKLLEPRLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MTKREAEELIEIEIDGTEKAECTEESIVEQTYAPAECVSQAIDINEPIGNLKKLLEPRLQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 CSLDAHEICLQDIQLDPERSLFDQGVKTDGTVQLSVQVISYQGIEPKLNILEIVKPADTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CSLDAHEICLQDIQLDPERSLFDQGVKTDGTVQLSVQVISYQGIEPKLNILEIVKPADTV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 EVVIDPDAHHAESEAHLVEEAQVITLDGTKHITTISDETSEQVTRWAAALEGYRKEQERL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EVVIDPDAHHAESEAHLVEEAQVITLDGTKHITTISDETSEQVTRWAAALEGYRKEQERL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 GIPYDPIQWSTDQVLHWVVWVMKEFSMTDIDLTTLNISGRELCSLNQEDFFQRVPRGEIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GIPYDPIQWSTDQVLHWVVWVMKEFSMTDIDLTTLNISGRELCSLNQEDFFQRVPRGEIL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 WSHLELLRKYVLASQEQQMNEIVTIDQPVQIIPASVQSATPTTIKVINSSAKAAKVQRAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WSHLELLRKYVLASQEQQMNEIVTIDQPVQIIPASVQSATPTTIKVINSSAKAAKVQRAP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 RISGEDRSSPGNRTGNNGQIQLWQFLLELLTDKDARDCISWVGDEGEFKLNQPELVAQKW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RISGEDRSSPGNRTGNNGQIQLWQFLLELLTDKDARDCISWVGDEGEFKLNQPELVAQKW 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 GQRKNKPTMNYEKLSRALRYYYDGDMICKVQGKRFVYKFVCDLKTLIGYSAAELNRLVTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GQRKNKPTMNYEKLSRALRYYYDGDMICKVQGKRFVYKFVCDLKTLIGYSAAELNRLVTE 370 380 390 400 410 420 430 440 450 pF1KB3 CEQKKLAKMQLHGIAQPVTAVALATASLQTEKDN :::::::::::::::::::::::::::::::::: XP_011 CEQKKLAKMQLHGIAQPVTAVALATASLQTEKDN 430 440 450 >>XP_016883802 (OMIM: 600609) PREDICTED: GA-binding prot (454 aa) initn: 2977 init1: 2977 opt: 2977 Z-score: 3425.2 bits: 643.0 E(85289): 4.8e-184 Smith-Waterman score: 2977; 100.0% identity (100.0% similar) in 454 aa overlap (1-454:1-454) 10 20 30 40 50 60 pF1KB3 MTKREAEELIEIEIDGTEKAECTEESIVEQTYAPAECVSQAIDINEPIGNLKKLLEPRLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MTKREAEELIEIEIDGTEKAECTEESIVEQTYAPAECVSQAIDINEPIGNLKKLLEPRLQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 CSLDAHEICLQDIQLDPERSLFDQGVKTDGTVQLSVQVISYQGIEPKLNILEIVKPADTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CSLDAHEICLQDIQLDPERSLFDQGVKTDGTVQLSVQVISYQGIEPKLNILEIVKPADTV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 EVVIDPDAHHAESEAHLVEEAQVITLDGTKHITTISDETSEQVTRWAAALEGYRKEQERL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EVVIDPDAHHAESEAHLVEEAQVITLDGTKHITTISDETSEQVTRWAAALEGYRKEQERL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 GIPYDPIQWSTDQVLHWVVWVMKEFSMTDIDLTTLNISGRELCSLNQEDFFQRVPRGEIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GIPYDPIQWSTDQVLHWVVWVMKEFSMTDIDLTTLNISGRELCSLNQEDFFQRVPRGEIL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 WSHLELLRKYVLASQEQQMNEIVTIDQPVQIIPASVQSATPTTIKVINSSAKAAKVQRAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WSHLELLRKYVLASQEQQMNEIVTIDQPVQIIPASVQSATPTTIKVINSSAKAAKVQRAP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 RISGEDRSSPGNRTGNNGQIQLWQFLLELLTDKDARDCISWVGDEGEFKLNQPELVAQKW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RISGEDRSSPGNRTGNNGQIQLWQFLLELLTDKDARDCISWVGDEGEFKLNQPELVAQKW 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 GQRKNKPTMNYEKLSRALRYYYDGDMICKVQGKRFVYKFVCDLKTLIGYSAAELNRLVTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GQRKNKPTMNYEKLSRALRYYYDGDMICKVQGKRFVYKFVCDLKTLIGYSAAELNRLVTE 370 380 390 400 410 420 430 440 450 pF1KB3 CEQKKLAKMQLHGIAQPVTAVALATASLQTEKDN :::::::::::::::::::::::::::::::::: XP_016 CEQKKLAKMQLHGIAQPVTAVALATASLQTEKDN 430 440 450 >>NP_001184226 (OMIM: 600609) GA-binding protein alpha c (454 aa) initn: 2977 init1: 2977 opt: 2977 Z-score: 3425.2 bits: 643.0 E(85289): 4.8e-184 Smith-Waterman score: 2977; 100.0% identity (100.0% similar) in 454 aa overlap (1-454:1-454) 10 20 30 40 50 60 pF1KB3 MTKREAEELIEIEIDGTEKAECTEESIVEQTYAPAECVSQAIDINEPIGNLKKLLEPRLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MTKREAEELIEIEIDGTEKAECTEESIVEQTYAPAECVSQAIDINEPIGNLKKLLEPRLQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 CSLDAHEICLQDIQLDPERSLFDQGVKTDGTVQLSVQVISYQGIEPKLNILEIVKPADTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CSLDAHEICLQDIQLDPERSLFDQGVKTDGTVQLSVQVISYQGIEPKLNILEIVKPADTV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 EVVIDPDAHHAESEAHLVEEAQVITLDGTKHITTISDETSEQVTRWAAALEGYRKEQERL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EVVIDPDAHHAESEAHLVEEAQVITLDGTKHITTISDETSEQVTRWAAALEGYRKEQERL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 GIPYDPIQWSTDQVLHWVVWVMKEFSMTDIDLTTLNISGRELCSLNQEDFFQRVPRGEIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GIPYDPIQWSTDQVLHWVVWVMKEFSMTDIDLTTLNISGRELCSLNQEDFFQRVPRGEIL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 WSHLELLRKYVLASQEQQMNEIVTIDQPVQIIPASVQSATPTTIKVINSSAKAAKVQRAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WSHLELLRKYVLASQEQQMNEIVTIDQPVQIIPASVQSATPTTIKVINSSAKAAKVQRAP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 RISGEDRSSPGNRTGNNGQIQLWQFLLELLTDKDARDCISWVGDEGEFKLNQPELVAQKW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RISGEDRSSPGNRTGNNGQIQLWQFLLELLTDKDARDCISWVGDEGEFKLNQPELVAQKW 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 GQRKNKPTMNYEKLSRALRYYYDGDMICKVQGKRFVYKFVCDLKTLIGYSAAELNRLVTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GQRKNKPTMNYEKLSRALRYYYDGDMICKVQGKRFVYKFVCDLKTLIGYSAAELNRLVTE 370 380 390 400 410 420 430 440 450 pF1KB3 CEQKKLAKMQLHGIAQPVTAVALATASLQTEKDN :::::::::::::::::::::::::::::::::: NP_001 CEQKKLAKMQLHGIAQPVTAVALATASLQTEKDN 430 440 450 >>XP_011527822 (OMIM: 600609) PREDICTED: GA-binding prot (454 aa) initn: 2977 init1: 2977 opt: 2977 Z-score: 3425.2 bits: 643.0 E(85289): 4.8e-184 Smith-Waterman score: 2977; 100.0% identity (100.0% similar) in 454 aa overlap (1-454:1-454) 10 20 30 40 50 60 pF1KB3 MTKREAEELIEIEIDGTEKAECTEESIVEQTYAPAECVSQAIDINEPIGNLKKLLEPRLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MTKREAEELIEIEIDGTEKAECTEESIVEQTYAPAECVSQAIDINEPIGNLKKLLEPRLQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 CSLDAHEICLQDIQLDPERSLFDQGVKTDGTVQLSVQVISYQGIEPKLNILEIVKPADTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CSLDAHEICLQDIQLDPERSLFDQGVKTDGTVQLSVQVISYQGIEPKLNILEIVKPADTV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 EVVIDPDAHHAESEAHLVEEAQVITLDGTKHITTISDETSEQVTRWAAALEGYRKEQERL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EVVIDPDAHHAESEAHLVEEAQVITLDGTKHITTISDETSEQVTRWAAALEGYRKEQERL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 GIPYDPIQWSTDQVLHWVVWVMKEFSMTDIDLTTLNISGRELCSLNQEDFFQRVPRGEIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GIPYDPIQWSTDQVLHWVVWVMKEFSMTDIDLTTLNISGRELCSLNQEDFFQRVPRGEIL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 WSHLELLRKYVLASQEQQMNEIVTIDQPVQIIPASVQSATPTTIKVINSSAKAAKVQRAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WSHLELLRKYVLASQEQQMNEIVTIDQPVQIIPASVQSATPTTIKVINSSAKAAKVQRAP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 RISGEDRSSPGNRTGNNGQIQLWQFLLELLTDKDARDCISWVGDEGEFKLNQPELVAQKW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RISGEDRSSPGNRTGNNGQIQLWQFLLELLTDKDARDCISWVGDEGEFKLNQPELVAQKW 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 GQRKNKPTMNYEKLSRALRYYYDGDMICKVQGKRFVYKFVCDLKTLIGYSAAELNRLVTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GQRKNKPTMNYEKLSRALRYYYDGDMICKVQGKRFVYKFVCDLKTLIGYSAAELNRLVTE 370 380 390 400 410 420 430 440 450 pF1KB3 CEQKKLAKMQLHGIAQPVTAVALATASLQTEKDN :::::::::::::::::::::::::::::::::: XP_011 CEQKKLAKMQLHGIAQPVTAVALATASLQTEKDN 430 440 450 >>XP_016883778 (OMIM: 165080) PREDICTED: transcriptional (428 aa) initn: 585 init1: 403 opt: 600 Z-score: 693.5 bits: 137.5 E(85289): 6.8e-32 Smith-Waterman score: 600; 42.3% identity (72.2% similar) in 227 aa overlap (177-399:122-339) 150 160 170 180 190 200 pF1KB3 DGTKHITTISDETSEQVTRWAAALEGYRKEQERLGIPYDPIQWSTDQVLHWVVWVMKEFS ..:. .: :: ::::.: .:. :..::.. XP_016 KMVGSPDTVGMNYGSYMEEKHMPPPNMTTNERRVIVPADPTLWSTDHVRQWLEWAVKEYG 100 110 120 130 140 150 210 220 230 240 250 260 pF1KB3 MTDIDLTTL-NISGRELCSLNQEDFFQRVPR--GEILWSHLELLRKYVLASQEQQMNEIV . :... . ::.:.:::.....:: . .: ..:: :::. ::. : . . . . XP_016 LPDVNILLFQNIDGKELCKMTKDDFQRLTPSYNADILLSHLHYLREN-LPYEPPRRSAWT 160 170 180 190 200 210 270 280 290 300 310 320 pF1KB3 TIDQPVQIIPASVQSATPTTIKVINSSAKAAKVQRAP-RISGEDRSSPGNRTGNNGQIQL .:. : : ..: :. : .. . . : : .: : : .: ..::::: XP_016 GHGHPT---PQS-KAAQPSPSTVPKTEDQ--RPQLDPYQILGPTSSRLAN--PGSGQIQL 220 230 240 250 260 330 340 350 360 370 380 pF1KB3 WQFLLELLTDKDARDCISWVGDEGEFKLNQPELVAQKWGQRKNKPTMNYEKLSRALRYYY ::::::::.:.. .::.: : .::::...:. ::..::.::.::.:::.:::::::::: XP_016 WQFLLELLSDSSNSSCITWEGTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYY 270 280 290 300 310 320 390 400 410 420 430 440 pF1KB3 DGDMICKVQGKRFVYKFVCDLKTLIGYSAAELNRLVTECEQKKLAKMQLHGIAQPVTAVA : ... ::.:::..::: XP_016 DKNIMTKVHGKRYAYKFDFHGIAQALQPHPPESSLYKYPSDLPYMGSYHAHPQKMNFVAP 330 340 350 360 370 380 >>XP_011527788 (OMIM: 165080) PREDICTED: transcriptional (435 aa) initn: 585 init1: 403 opt: 600 Z-score: 693.4 bits: 137.5 E(85289): 6.9e-32 Smith-Waterman score: 600; 42.3% identity (72.2% similar) in 227 aa overlap (177-399:129-346) 150 160 170 180 190 200 pF1KB3 DGTKHITTISDETSEQVTRWAAALEGYRKEQERLGIPYDPIQWSTDQVLHWVVWVMKEFS ..:. .: :: ::::.: .:. :..::.. XP_011 KMVGSPDTVGMNYGSYMEEKHMPPPNMTTNERRVIVPADPTLWSTDHVRQWLEWAVKEYG 100 110 120 130 140 150 210 220 230 240 250 260 pF1KB3 MTDIDLTTL-NISGRELCSLNQEDFFQRVPR--GEILWSHLELLRKYVLASQEQQMNEIV . :... . ::.:.:::.....:: . .: ..:: :::. ::. : . . . . XP_011 LPDVNILLFQNIDGKELCKMTKDDFQRLTPSYNADILLSHLHYLREN-LPYEPPRRSAWT 160 170 180 190 200 210 270 280 290 300 310 320 pF1KB3 TIDQPVQIIPASVQSATPTTIKVINSSAKAAKVQRAP-RISGEDRSSPGNRTGNNGQIQL .:. : : ..: :. : .. . . : : .: : : .: ..::::: XP_011 GHGHPT---PQS-KAAQPSPSTVPKTEDQ--RPQLDPYQILGPTSSRLAN--PGSGQIQL 220 230 240 250 260 330 340 350 360 370 380 pF1KB3 WQFLLELLTDKDARDCISWVGDEGEFKLNQPELVAQKWGQRKNKPTMNYEKLSRALRYYY ::::::::.:.. .::.: : .::::...:. ::..::.::.::.:::.:::::::::: XP_011 WQFLLELLSDSSNSSCITWEGTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYY 270 280 290 300 310 320 390 400 410 420 430 440 pF1KB3 DGDMICKVQGKRFVYKFVCDLKTLIGYSAAELNRLVTECEQKKLAKMQLHGIAQPVTAVA : ... ::.:::..::: XP_011 DKNIMTKVHGKRYAYKFDFHGIAQALQPHPPESSLYKYPSDLPYMGSYHAHPQKMNFVAP 330 340 350 360 370 380 >>NP_001317380 (OMIM: 164720) protein C-ets-1 isoform 4 (354 aa) initn: 715 init1: 459 opt: 473 Z-score: 548.8 bits: 110.4 E(85289): 7.9e-24 Smith-Waterman score: 670; 39.6% identity (62.0% similar) in 313 aa overlap (152-418:37-346) 130 140 150 160 170 180 pF1KB3 VVIDPDAHHAESEAHLVEEAQVITLDGTKHITTISDETSEQVTRWAAALEGYRKEQERLG .: : : :. . :.. :. :::.::: NP_001 LKPTLTIIKTEKVDLELFPSPDMECADVPLLTPSSKEMMSQALK--ATFSGFTKEQQRLG 10 20 30 40 50 60 190 200 210 220 230 pF1KB3 IPYDPIQWSTDQVLHWVVWVMKEFSMTDIDLTTLNISGRELCSLNQEDFFQRVPR--GEI :: :: ::. .: ::.:...:::. .:. . ..: ::.:... :.. .: :.: NP_001 IPKDPRQWTETHVRDWVMWAVNEFSLKGVDFQKFCMNGAALCALGKDCFLELAPDFVGDI 70 80 90 100 110 120 240 250 260 270 280 pF1KB3 LWSHLELLRKY-VLASQEQQMNEIV-----TID-------QPVQIIPASVQSATPT---- :: :::.:.: : : . .: : : . .: .: : . . :. NP_001 LWEHLEILQKEDVKPYQVNGVNPAYPESRYTSDYFISYGIEHAQCVPPS-EFSEPSFITE 130 140 150 160 170 180 290 300 310 pF1KB3 ---TIKVINS----SAKAAK-----VQRAP---------------RISGEDRSSPGNRTG :.. :.: : : . . : : .. : : . NP_001 SYQTLHPISSEELLSLKYENDYPSVILRDPLQTDTLQNDYFAIKQEVVTPDNMCMGRTSR 190 200 210 220 230 240 320 330 340 350 360 370 pF1KB3 NNGQIQLWQFLLELLTDKDARDCISWVGDEGEFKLNQPELVAQKWGQRKNKPTMNYEKLS ..: ::::::::::::::. .. :::.:: ::::..:. ::..::.::::: ::::::: NP_001 GSGPIQLWQFLLELLTDKSCQSFISWTGDGWEFKLSDPDEVARRWGKRKNKPKMNYEKLS 250 260 270 280 290 300 380 390 400 410 420 430 pF1KB3 RALRYYYDGDMICKVQGKRFVYKFVCDLKTLIGYSAAELNRLVTECEQKKLAKMQLHGIA :.:::::: ..: :. :::.::.:::::..:.::. ::. .. NP_001 RGLRYYYDKNIIHKTAGKRYVYRFVCDLQSLLGYTPEELHAMLDVKPDADE 310 320 330 340 350 440 450 pF1KB3 QPVTAVALATASLQTEKDN >>XP_016872806 (OMIM: 164720) PREDICTED: protein C-ets-1 (398 aa) initn: 715 init1: 459 opt: 473 Z-score: 548.0 bits: 110.5 E(85289): 8.7e-24 Smith-Waterman score: 670; 39.6% identity (62.0% similar) in 313 aa overlap (152-418:81-390) 130 140 150 160 170 180 pF1KB3 VVIDPDAHHAESEAHLVEEAQVITLDGTKHITTISDETSEQVTRWAAALEGYRKEQERLG .: : : :. . :.. :. :::.::: XP_016 YPFWDEMATQEVPTGLEHCVSDMECADVPLLTPSSKEMMSQALK--ATFSGFTKEQQRLG 60 70 80 90 100 190 200 210 220 230 pF1KB3 IPYDPIQWSTDQVLHWVVWVMKEFSMTDIDLTTLNISGRELCSLNQEDFFQRVPR--GEI :: :: ::. .: ::.:...:::. .:. . ..: ::.:... :.. .: :.: XP_016 IPKDPRQWTETHVRDWVMWAVNEFSLKGVDFQKFCMNGAALCALGKDCFLELAPDFVGDI 110 120 130 140 150 160 240 250 260 270 280 pF1KB3 LWSHLELLRKY-VLASQEQQMNEIV-----TID-------QPVQIIPASVQSATPT---- :: :::.:.: : : . .: : : . .: .: : . . :. XP_016 LWEHLEILQKEDVKPYQVNGVNPAYPESRYTSDYFISYGIEHAQCVPPS-EFSEPSFITE 170 180 190 200 210 220 290 300 310 pF1KB3 ---TIKVINS----SAKAAK-----VQRAP---------------RISGEDRSSPGNRTG :.. :.: : : . . : : .. : : . XP_016 SYQTLHPISSEELLSLKYENDYPSVILRDPLQTDTLQNDYFAIKQEVVTPDNMCMGRTSR 230 240 250 260 270 280 320 330 340 350 360 370 pF1KB3 NNGQIQLWQFLLELLTDKDARDCISWVGDEGEFKLNQPELVAQKWGQRKNKPTMNYEKLS ..: ::::::::::::::. .. :::.:: ::::..:. ::..::.::::: ::::::: XP_016 GSGPIQLWQFLLELLTDKSCQSFISWTGDGWEFKLSDPDEVARRWGKRKNKPKMNYEKLS 290 300 310 320 330 340 380 390 400 410 420 430 pF1KB3 RALRYYYDGDMICKVQGKRFVYKFVCDLKTLIGYSAAELNRLVTECEQKKLAKMQLHGIA :.:::::: ..: :. :::.::.:::::..:.::. ::. .. XP_016 RGLRYYYDKNIIHKTAGKRYVYRFVCDLQSLLGYTPEELHAMLDVKPDADE 350 360 370 380 390 440 450 pF1KB3 QPVTAVALATASLQTEKDN 454 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 02:43:28 2016 done: Fri Nov 4 02:43:29 2016 Total Scan time: 7.070 Total Display time: 0.050 Function used was FASTA [36.3.4 Apr, 2011]