FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3912, 153 aa 1>>>pF1KB3912 153 - 153 aa - 153 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.8348+/-0.000642; mu= 14.4385+/- 0.039 mean_var=61.3337+/-12.291, 0's: 0 Z-trim(110.6): 20 B-trim: 0 in 0/52 Lambda= 0.163766 statistics sampled from 11683 (11699) to 11683 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.745), E-opt: 0.2 (0.359), width: 16 Scan time: 1.840 The best scores are: opt bits E(32554) CCDS9091.1 IGF1 gene_id:3479|Hs108|chr12 ( 153) 1058 257.6 2.1e-69 CCDS44961.1 IGF1 gene_id:3479|Hs108|chr12 ( 158) 934 228.3 1.4e-60 CCDS44960.1 IGF1 gene_id:3479|Hs108|chr12 ( 137) 902 220.7 2.4e-58 CCDS7728.1 IGF2 gene_id:3481|Hs108|chr11 ( 180) 317 82.6 1.2e-16 CCDS44517.1 IGF2 gene_id:3481|Hs108|chr11 ( 236) 317 82.7 1.5e-16 >>CCDS9091.1 IGF1 gene_id:3479|Hs108|chr12 (153 aa) initn: 1058 init1: 1058 opt: 1058 Z-score: 1359.4 bits: 257.6 E(32554): 2.1e-69 Smith-Waterman score: 1058; 100.0% identity (100.0% similar) in 153 aa overlap (1-153:1-153) 10 20 30 40 50 60 pF1KB3 MGKISSLPTQLFKCCFCDFLKVKMHTMSSSHLFYLALCLLTFTSSATAGPETLCGAELVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS90 MGKISSLPTQLFKCCFCDFLKVKMHTMSSSHLFYLALCLLTFTSSATAGPETLCGAELVD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 ALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPAKSARS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS90 ALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPAKSARS 70 80 90 100 110 120 130 140 150 pF1KB3 VRAQRHTDMPKTQKEVHLKNASRGSAGNKNYRM ::::::::::::::::::::::::::::::::: CCDS90 VRAQRHTDMPKTQKEVHLKNASRGSAGNKNYRM 130 140 150 >>CCDS44961.1 IGF1 gene_id:3479|Hs108|chr12 (158 aa) initn: 934 init1: 934 opt: 934 Z-score: 1200.9 bits: 228.3 E(32554): 1.4e-60 Smith-Waterman score: 934; 100.0% identity (100.0% similar) in 134 aa overlap (1-134:1-134) 10 20 30 40 50 60 pF1KB3 MGKISSLPTQLFKCCFCDFLKVKMHTMSSSHLFYLALCLLTFTSSATAGPETLCGAELVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 MGKISSLPTQLFKCCFCDFLKVKMHTMSSSHLFYLALCLLTFTSSATAGPETLCGAELVD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 ALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPAKSARS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 ALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPAKSARS 70 80 90 100 110 120 130 140 150 pF1KB3 VRAQRHTDMPKTQKEVHLKNASRGSAGNKNYRM :::::::::::::: CCDS44 VRAQRHTDMPKTQKYQPPSTNKNTKSQRRKGSTFEERK 130 140 150 >>CCDS44960.1 IGF1 gene_id:3479|Hs108|chr12 (137 aa) initn: 902 init1: 902 opt: 902 Z-score: 1160.9 bits: 220.7 E(32554): 2.4e-58 Smith-Waterman score: 902; 100.0% identity (100.0% similar) in 132 aa overlap (22-153:6-137) 10 20 30 40 50 60 pF1KB3 MGKISSLPTQLFKCCFCDFLKVKMHTMSSSHLFYLALCLLTFTSSATAGPETLCGAELVD ::::::::::::::::::::::::::::::::::::::: CCDS44 MITPTVKMHTMSSSHLFYLALCLLTFTSSATAGPETLCGAELVD 10 20 30 40 70 80 90 100 110 120 pF1KB3 ALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPAKSARS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 ALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPAKSARS 50 60 70 80 90 100 130 140 150 pF1KB3 VRAQRHTDMPKTQKEVHLKNASRGSAGNKNYRM ::::::::::::::::::::::::::::::::: CCDS44 VRAQRHTDMPKTQKEVHLKNASRGSAGNKNYRM 110 120 130 >>CCDS7728.1 IGF2 gene_id:3481|Hs108|chr11 (180 aa) initn: 319 init1: 168 opt: 317 Z-score: 412.3 bits: 82.6 E(32554): 1.2e-16 Smith-Waterman score: 317; 58.2% identity (74.5% similar) in 98 aa overlap (27-121:5-94) 10 20 30 40 50 pF1KB3 MGKISSLPTQLFKCCFCDFLKVKMHTMSSSHLFYLALCLLTFTSSATAG--P-ETLCGAE :..: : :.. :.:.: :. : :::::.: CCDS77 MGIPMGKSMLVLLTF--LAFASCCIAAYRPSETLCGGE 10 20 30 60 70 80 90 100 110 pF1KB3 LVDALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPAKS :::.::::::::::::..:.. :::. :::.::::::::: :: ::: :::: CCDS77 LVDTLQFVCGDRGFYFSRPASR--VSRRS--RGIVEECCFRSCDLALLETYCA--TPAKS 40 50 60 70 80 90 120 130 140 150 pF1KB3 ARSVRAQRHTDMPKTQKEVHLKNASRGSAGNKNYRM :.: CCDS77 ERDVSTPPTVLPDNFPRYPVGKFFQYDTWKQSTQRLRRGLPALLRARRGHVLAKELEAFR 100 110 120 130 140 150 >>CCDS44517.1 IGF2 gene_id:3481|Hs108|chr11 (236 aa) initn: 306 init1: 168 opt: 317 Z-score: 410.6 bits: 82.7 E(32554): 1.5e-16 Smith-Waterman score: 317; 58.2% identity (74.5% similar) in 98 aa overlap (27-121:61-150) 10 20 30 40 50 pF1KB3 MGKISSLPTQLFKCCFCDFLKVKMHTMSSSHLFYLALCLLTFTSSATAG--P-ETL :..: : :.. :.:.: :. : ::: CCDS44 IIQIFWVGRKGELLRRTPVSSAMQTPMGIPMGKSMLVLLTF--LAFASCCIAAYRPSETL 40 50 60 70 80 60 70 80 90 100 110 pF1KB3 CGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLK ::.::::.::::::::::::..:.. :::. :::.::::::::: :: ::: CCDS44 CGGELVDTLQFVCGDRGFYFSRPASR--VSRRS--RGIVEECCFRSCDLALLETYCA--T 90 100 110 120 130 140 120 130 140 150 pF1KB3 PAKSARSVRAQRHTDMPKTQKEVHLKNASRGSAGNKNYRM :::: :.: CCDS44 PAKSERDVSTPPTVLPDNFPRYPVGKFFQYDTWKQSTQRLRRGLPALLRARRGHVLAKEL 150 160 170 180 190 200 153 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 14:10:09 2016 done: Thu Nov 3 14:10:09 2016 Total Scan time: 1.840 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]