Result of FASTA (omim) for pF1KB3946
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB3946, 509 aa
  1>>>pF1KB3946 509 - 509 aa - 509 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 14.6584+/-0.000451; mu= -22.4982+/- 0.028
 mean_var=667.1116+/-138.572, 0's: 0 Z-trim(125.1): 59  B-trim: 0 in 0/62
 Lambda= 0.049656
 statistics sampled from 48082 (48152) to 48082 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.812), E-opt: 0.2 (0.565), width:  16
 Scan time:  8.980

The best scores are:                                      opt bits E(85289)
NP_000337 (OMIM: 114290,608160,616425) transcripti ( 509) 3554 269.3 1.9e-71
NP_008872 (OMIM: 602229,609136,611584,613266) tran ( 466) 1350 111.4   6e-24
NP_055402 (OMIM: 605923) transcription factor SOX- ( 446) 1178 99.0   3e-20
NP_071899 (OMIM: 610928,613674) transcription fact ( 414)  534 52.9 2.2e-06
NP_113627 (OMIM: 612202) transcription factor SOX- ( 388)  461 47.6 7.8e-05
NP_060889 (OMIM: 137940,601618,607823) transcripti ( 384)  430 45.4 0.00036
NP_009015 (OMIM: 604974) transcription factor SOX- ( 276)  423 44.8  0.0004
NP_008873 (OMIM: 601297) protein SOX-15 [Homo sapi ( 233)  408 43.6 0.00074
NP_004180 (OMIM: 604747) transcription factor SOX- ( 240)  405 43.4 0.00088
NP_003097 (OMIM: 184429,189960,206900) transcripti ( 317)  407 43.7 0.00098
NP_005625 (OMIM: 300123,312000,313430) transcripti ( 446)  397 43.1  0.0021
NP_008874 (OMIM: 601947) transcription factor SOX- ( 315)  385 42.1  0.0029
NP_003098 (OMIM: 184430) transcription factor SOX- ( 474)  387 42.4  0.0035
NP_005977 (OMIM: 602148) transcription factor SOX- ( 391)  381 41.9  0.0041
NP_003099 (OMIM: 600898,615866) transcription fact ( 441)  379 41.8   0.005


>>NP_000337 (OMIM: 114290,608160,616425) transcription f  (509 aa)
 initn: 3554 init1: 3554 opt: 3554  Z-score: 1403.8  bits: 269.3 E(85289): 1.9e-71
Smith-Waterman score: 3554; 100.0% identity (100.0% similar) in 509 aa overlap (1-509:1-509)

               10        20        30        40        50        60
pF1KB3 MNLLDPFMKMTDEQEKGLSGAPSPTMSEDSAGSPCPSGSGSDTENTRPQENTFPKGEPDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MNLLDPFMKMTDEQEKGLSGAPSPTMSEDSAGSPCPSGSGSDTENTRPQENTFPKGEPDL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 KKESEEDKFPVCIREAVSQVLKGYDWTLVPMPVRVNGSSKNKPHVKRPMNAFMVWAQAAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 KKESEEDKFPVCIREAVSQVLKGYDWTLVPMPVRVNGSSKNKPHVKRPMNAFMVWAQAAR
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 RKLADQYPHLHNAELSKTLGKLWRLLNESEKRPFVEEAERLRVQHKKDHPDYKYQPRRRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RKLADQYPHLHNAELSKTLGKLWRLLNESEKRPFVEEAERLRVQHKKDHPDYKYQPRRRK
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 SVKNGQAEAEEATEQTHISPNAIFKALQADSPHSSSGMSEVHSPGEHSGQSQGPPTPPTT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SVKNGQAEAEEATEQTHISPNAIFKALQADSPHSSSGMSEVHSPGEHSGQSQGPPTPPTT
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 PKTDVQPGKADLKREGRPLPEGGRQPPIDFRDVDIGELSSDVISNIETFDVNEFDQYLPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PKTDVQPGKADLKREGRPLPEGGRQPPIDFRDVDIGELSSDVISNIETFDVNEFDQYLPP
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 NGHPGVPATHGQVTYTGSYGISSTAATPASAGHVWMSKQQAPPPPPQQPPQAPPAPQAPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 NGHPGVPATHGQVTYTGSYGISSTAATPASAGHVWMSKQQAPPPPPQQPPQAPPAPQAPP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 QPQAAPPQQPAAPPQQPQAHTLTTLSSEPGQSQRTHIKTEQLSPSHYSEQQQHSPQQIAY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 QPQAAPPQQPAAPPQQPQAHTLTTLSSEPGQSQRTHIKTEQLSPSHYSEQQQHSPQQIAY
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB3 SPFNLPHYSPSYPPITRSQYDYTDHQNSSSYYSHAAGQGTGLYSTFTYMNPAQRPMYTPI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SPFNLPHYSPSYPPITRSQYDYTDHQNSSSYYSHAAGQGTGLYSTFTYMNPAQRPMYTPI
              430       440       450       460       470       480

              490       500         
pF1KB3 ADTSGVPSIPQTHSPQHWEQPVYTQLTRP
       :::::::::::::::::::::::::::::
NP_000 ADTSGVPSIPQTHSPQHWEQPVYTQLTRP
              490       500         

>>NP_008872 (OMIM: 602229,609136,611584,613266) transcri  (466 aa)
 initn: 1439 init1: 805 opt: 1350  Z-score: 551.0  bits: 111.4 E(85289): 6e-24
Smith-Waterman score: 1682; 54.4% identity (72.1% similar) in 502 aa overlap (13-509:18-466)

                    10        20        30        40        50     
pF1KB3      MNLLDPFMKMTDEQEKGLSGAPSPTMSEDSAGSPCPSGSGSDTENTRPQENTFPK
                        :. . :: . .:... :..:.    :::  .     . .   :
NP_008 MAEEQDLSEVELSPVGSEEPRCLSPGSAPSLGPDGGGG----GSGLRASPGPGELGKVKK
               10        20        30            40        50      

          60        70        80        90       100       110     
pF1KB3 GEPDLKKESEEDKFPVCIREAVSQVLKGYDWTLVPMPVRVNGSSKNKPHVKRPMNAFMVW
        . :   :...:::::::::::::::.:::::::::::::::.::.::::::::::::::
NP_008 EQQD--GEADDDKFPVCIREAVSQVLSGYDWTLVPMPVRVNGASKSKPHVKRPMNAFMVW
         60          70        80        90       100       110    

         120       130       140       150       160       170     
pF1KB3 AQAARRKLADQYPHLHNAELSKTLGKLWRLLNESEKRPFVEEAERLRVQHKKDHPDYKYQ
       ::::::::::::::::::::::::::::::::::.::::.:::::::.::::::::::::
NP_008 AQAARRKLADQYPHLHNAELSKTLGKLWRLLNESDKRPFIEEAERLRMQHKKDHPDYKYQ
          120       130       140       150       160       170    

         180       190           200       210       220        230
pF1KB3 PRRRKSVKNGQAEAE----EATEQTHISPNAIFKALQADSPHSSSGMSEVHSPGEH-SGQ
       :::::. : .:.:::    :: .    . .: .:. . :  : . :     .  :: :::
NP_008 PRRRKNGKAAQGEAECPGGEAEQGGTAAIQAHYKSAHLDHRHPGEGSPMSDGNPEHPSGQ
          180       190       200       210       220       230    

              240       250       260       270       280       290
pF1KB3 SQGPPTPPTTPKTDVQPGKADLKREGRPLPEGGRQPPIDFRDVDIGELSSDVISNIETFD
       :.:::::::::::..: :::: ::.:: . :::. : ::: .:::::.: .:.::.::::
NP_008 SHGPPTPPTTPKTELQSGKADPKRDGRSMGEGGK-PHIDFGNVDIGEISHEVMSNMETFD
          240       250       260        270       280       290   

              300       310       320       330       340       350
pF1KB3 VNEFDQYLPPNGHPGVPATHGQVTYTGSYGISSTAATPASAGHVWMSKQQAPPPPPQQPP
       : :.:::::::::::    : .   ...::..:. :. ::.  .:.::    ::    : 
NP_008 VAELDQYLPPNGHPG----HVSSYSAAGYGLGSALAV-ASGHSAWISK----PPGVALPT
           300           310       320        330           340    

              360       370       380       390       400       410
pF1KB3 QAPPAPQAPPQPQAAPPQQPAAPPQQPQAHTLTTLSSEPGQSQRTHIKTEQLSPSHYSEQ
        .::. .:  : ..      .: ::                           .: ::..:
NP_008 VSPPGVDAKAQVKTE-----TAGPQ---------------------------GPPHYTDQ
          350            360                                  370  

              420       430       440       450       460       470
pF1KB3 QQHSPQQIAYSPFNLPHYSPSYPPITRSQYDYTDHQNSSSYYSHAAGQGTGLYSTFTYMN
          : .::::. ..::::. ..: :.: :.::.::: :. ::.:. ::..::::.:.::.
NP_008 P--STSQIAYTSLSLPHYGSAFPSISRPQFDYSDHQPSGPYYGHS-GQASGLYSAFSYMG
              380       390       400       410        420         

              480       490       500         
pF1KB3 PAQRPMYTPIADTSGVPSIPQTHSPQHWEQPVYTQLTRP
       :.:::.:: :.: :  :: ::.::: :::::::: :.::
NP_008 PSQRPLYTAISDPS--PSGPQSHSPTHWEQPVYTTLSRP
     430       440         450       460      

>>NP_055402 (OMIM: 605923) transcription factor SOX-8 [H  (446 aa)
 initn: 1081 init1: 586 opt: 1178  Z-score: 484.6  bits: 99.0 E(85289): 3e-20
Smith-Waterman score: 1339; 48.8% identity (67.6% similar) in 500 aa overlap (19-509:16-446)

               10        20         30        40        50         
pF1KB3 MNLLDPFMKMTDEQEKGLSG-APSPTMSEDSAGSPCPSGSGSDTENTRPQENTFPKGEPD
                         :: : : .  ::: ..  :: .::.  .         .:.: 
NP_055    MLDMSEARSQPPCSPSGTASSMSHVEDSDSDAPPSPAGSEGLGRAGVAVGGARGDP-
                  10        20        30        40        50       

      60        70        80        90         100       110       
pF1KB3 LKKESEEDKFPVCIREAVSQVLKGYDWTLVPMPVRVNGSS--KNKPHVKRPMNAFMVWAQ
          :. ...::.:::.:::::::::::.::::::: .:..  : ::::::::::::::::
NP_055 --AEAADERFPACIRDAVSQVLKGYDWSLVPMPVRGGGGGALKAKPHVKRPMNAFMVWAQ
           60        70        80        90       100       110    

       120       130       140       150       160       170       
pF1KB3 AARRKLADQYPHLHNAELSKTLGKLWRLLNESEKRPFVEEAERLRVQHKKDHPDYKYQPR
       :::::::::::::::::::::::::::::.::::::::::::::::::::::::::::::
NP_055 AARRKLADQYPHLHNAELSKTLGKLWRLLSESEKRPFVEEAERLRVQHKKDHPDYKYQPR
          120       130       140       150       160       170    

       180       190        200       210       220       230      
pF1KB3 RRKSVKNGQAEAEEATEQ-THISPNAIFKALQADSPHSSSGMSEVHSPGEHSGQSQGPPT
       ::::.: :..... ..:   : . .:..::         .:... :  :.:.::..::::
NP_055 RRKSAKAGHSDSDSGAELGPHPGGGAVYKA--------EAGLGDGHHHGDHTGQTHGPPT
          180       190       200               210       220      

        240         250       260       270       280       290    
pF1KB3 PPTTPKTDVQPG--KADLKREGRPLPEGGRQPPIDFRDVDIGELSSDVISNIETFDVNEF
       :::::::..: .  : .:: :::   ..:::  ::: .:::.::::.:......:::.::
NP_055 PPTTPKTELQQAGAKPELKLEGRRPVDSGRQN-IDFSNVDISELSSEVMGTMDAFDVHEF
        230       240       250        260       270       280     

          300       310       320       330       340       350    
pF1KB3 DQYLPPNGHPGVPATHGQVTYTGSYGISSTAATPASAGHVWMSKQQAPPPPPQQPPQAPP
       ::::: .: :. :   ::. : :.:         :.:. ::  :. ::        .: :
NP_055 DQYLPLGG-PA-PPEPGQA-YGGAY-------FHAGASPVWAHKS-APSA------SASP
         290         300               310       320               

          360       370       380       390       400       410    
pF1KB3 APQAPPQPQAAPPQQPAAPPQQPQAHTLTTLSSEPGQSQRTHIKTEQLSPSHYSEQQQHS
       .  .::.:                                 :::::: ::.::..: . :
NP_055 TETGPPRP---------------------------------HIKTEQPSPGHYGDQPRGS
      330                                        340       350     

          420       430         440       450       460       470  
pF1KB3 PQQIAYSPFNLPHYSPSYP--PITRSQYDYTDHQNSSSYYSHAAGQGTGLYSTFTYMNPA
       :.  . :  .    .:. :  :.. :: :: : : .::::.   : . :::.   . .: 
NP_055 PDYGSCS--GQSSATPAAPAGPFAGSQGDYGDLQ-ASSYYGAYPGYAPGLYQYPCFHSP-
         360         370       380        390       400       410  

            480       490        500         
pF1KB3 QRPMYTPIADTSGVPSIPQTHSP-QHWEQPVYTQLTRP
       .::. .:. .  :. ..: .::: .::.::::: ::::
NP_055 RRPYASPLLN--GL-ALPPAHSPTSHWDQPVYTTLTRP
             420          430       440      

>>NP_071899 (OMIM: 610928,613674) transcription factor S  (414 aa)
 initn: 513 init1: 429 opt: 534  Z-score: 235.7  bits: 52.9 E(85289): 2.2e-06
Smith-Waterman score: 534; 34.6% identity (54.4% similar) in 344 aa overlap (92-426:55-389)

              70        80        90       100       110       120 
pF1KB3 KESEEDKFPVCIREAVSQVLKGYDWTLVPMPVRVNGSSKNKPHVKRPMNAFMVWAQAARR
                                     :. . : .:.. ...::::::::::.  :.
NP_071 AGLGPCPWAESLSPIGDMKVKGEAPANSGAPAGAAGRAKGESRIRRPMNAFMVWAKDERK
           30        40        50        60        70        80    

             130       140       150       160       170       180 
pF1KB3 KLADQYPHLHNAELSKTLGKLWRLLNESEKRPFVEEAERLRVQHKKDHPDYKYQPRRRKS
       .::.: : :::::::: ::: :. :. .:::::::::::::::: .:::.:::.:::::.
NP_071 RLAQQNPDLHNAELSKMLGKSWKALTLAEKRPFVEEAERLRVQHMQDHPNYKYRPRRRKQ
           90       100       110       120       130       140    

             190       200       210       220       230        240
pF1KB3 VKNGQAEAEEATEQTHISPNAIFKALQADSPHSSSGMSEVHSPGEHSGQSQGPPT-PPTT
       ::  . ..: .  .    :.:   ::  .. . .     .. :  ..:   :::  ::  
NP_071 VKRLK-RVEGGFLHGLAEPQAA--ALGPEGGRVAMDGLGLQFP--EQGFPAGPPLLPPHM
           150       160         170       180         190         

                 250       260       270       280       290       
pF1KB3 PK--TDVQP-GKADLKREGRPLPEGGRQPPIDFRDVDIGELSSDVISNIETFDVNEFDQY
            : :  :   :  .: :::    .: .:  : : . ... . ..  .  .  . : 
NP_071 GGHYRDCQSLGAPPL--DGYPLPTPDTSP-LDGVDPDPAFFAAPMPGDCPAAGTYSYAQV
     200       210         220        230       240       250      

       300         310       320       330       340       350     
pF1KB3 LPPNGHPGVPA--THGQVTYTGSYGISSTAATPASAGHVWMSKQQAPPPPPQQPPQAPPA
           : :  ::   : ..    .        .: :: ::... . .:     .  :  : 
NP_071 SDYAGPPEPPAGPMHPRLGPEPAGPSIPGLLAPPSALHVYYGAMGSPGAGGGRGFQMQPQ
        260       270       280       290       300       310      

         360         370       380       390       400       410   
pF1KB3 PQAPPQPQAAPPQ--QPAAPPQQPQAHTLTTLSSEPGQSQRTHIKTEQLSPSHYSEQQQH
        :   : :  ::   ::. ::.    .  :   :.:..      .::  .  :.  . . 
NP_071 HQHQHQHQHHPPGPGQPSPPPEALPCRDGTD-PSQPAELLGEVDRTEFEQYLHFVCKPEM
        320       330       340        350       360       370     

            420       430       440       450       460       470  
pF1KB3 S-PQQIAYSPFNLPHYSPSYPPITRSQYDYTDHQNSSSYYSHAAGQGTGLYSTFTYMNPA
       . : :   :  :::                                              
NP_071 GLPYQGHDSGVNLPDSHGAISSVVSDASSAVYYCNYPDV                     
         380       390       400       410                         

>>NP_113627 (OMIM: 612202) transcription factor SOX-7 [H  (388 aa)
 initn: 479 init1: 383 opt: 461  Z-score: 207.8  bits: 47.6 E(85289): 7.8e-05
Smith-Waterman score: 461; 32.5% identity (54.8% similar) in 323 aa overlap (89-406:32-341)

       60        70        80        90       100       110        
pF1KB3 DLKKESEEDKFPVCIREAVSQVLKGYDWTLVPMPVRVNGSSKNKPHVKRPMNAFMVWAQA
                                     :: :    :.. .. ...::::::::::. 
NP_113 ASLLGAYPWPEGLECPALDAELSDGQSPPAVPRP---PGDKGSESRIRRPMNAFMVWAKD
              10        20        30           40        50        

      120       130       140       150       160       170        
pF1KB3 ARRKLADQYPHLHNAELSKTLGKLWRLLNESEKRPFVEEAERLRVQHKKDHPDYKYQPRR
        :..:: : : :::::::: ::: :. :. :.:::.:.::::::.:: .:.:.:::.:::
NP_113 ERKRLAVQNPDLHNAELSKMLGKSWKALTLSQKRPYVDEAERLRLQHMQDYPNYKYRPRR
       60        70        80        90       100       110        

      180       190       200       210       220       230        
pF1KB3 RKSVKNGQAEAEEATEQTHISPNAIFKALQADSPHSSSGMSEVHSPGEHSGQSQGPPTPP
       .:..:    ... .   . .: .   .::      : ....: .. ::.:  .  :    
NP_113 KKQAKRLCKRVDPGFLLSSLSRDQ--NALPEKRSGSRGALGEKEDRGEYSPGTALPSLRG
      120       130       140         150       160       170      

      240       250       260       270       280         290      
pF1KB3 TTPKTDVQPGKADLKREGRPLPEGGRQPPIDFRDVDIGELSSDVISNI--ETFDVNEFDQ
          .  .  : .         : :   :: ..  .:. :  .  .:.   :     .   
NP_113 CYHEGPAGGGGGGTPSSVDTYPYGLPTPP-EMSPLDVLEPEQTFFSSPCQEEHGHPRRIP
        180       190       200        210       220       230     

        300       310       320       330       340       350      
pF1KB3 YLPPNGHPGVPATHGQVTYTGSYGISSTAATPASAGHVWMSKQQAPPPPPQQPPQAPPAP
       .::  :::  :  ..      :. ..: :    : :   ::   .:  ::. :    :: 
NP_113 HLP--GHPYSPE-YAPSPLHCSHPLGSLA-LGQSPGVSMMSP--VPGCPPS-PAYYSPAT
           240        250       260        270         280         

        360        370       380         390       400       410   
pF1KB3 QAPPQPQ-AAPPQQPAAPPQQPQAHTLTTLSSEP--GQSQRTHIKTEQLSPSHYSEQQQH
         : . .  :   : . ::..:   .:  ::.    :. .:...     .:.:       
NP_113 YHPLHSNLQAHLGQLSPPPEHPGFDALDQLSQVELLGDMDRNEFDQYLNTPGHPDSATGA
      290       300       310       320       330       340        

           420       430       440       450       460       470   
pF1KB3 SPQQIAYSPFNLPHYSPSYPPITRSQYDYTDHQNSSSYYSHAAGQGTGLYSTFTYMNPAQ
                                                                   
NP_113 MALSGHVPVSQVTPTGPTETSLISVLADATATYYNSYSVS                    
      350       360       370       380                            

>>NP_060889 (OMIM: 137940,601618,607823) transcription f  (384 aa)
 initn: 459 init1: 391 opt: 430  Z-score: 195.9  bits: 45.4 E(85289): 0.00036
Smith-Waterman score: 468; 32.3% identity (52.9% similar) in 359 aa overlap (17-372:7-316)

               10        20        30        40        50        60
pF1KB3 MNLLDPFMKMTDEQEKGLSGAPSPTMSEDSAGSPCPSGSGSDTENTRPQENTFPKGEPDL
                       : ..  .:   .: : .:   :...::..       .  :   :
NP_060           MQRSPPGYGAQDDPPARRDCAWAP-GHGAAADTRG-------LAAGPAAL
                         10        20         30               40  

               70        80        90       100       110       120
pF1KB3 KKESEEDKFPVCIREAVSQVLKGYDWTLVPMPVRVNGSSKNKPHVKRPMNAFMVWAQAAR
          .   . :   :    .   :  . : :   : . .. .. ...::::::::::.  :
NP_060 AAPAAPASPPSPQRSPPRSPEPGR-YGLSPAG-RGERQAADESRIRRPMNAFMVWAKDER
             50        60         70         80        90       100

              130       140       150       160       170       180
pF1KB3 RKLADQYPHLHNAELSKTLGKLWRLLNESEKRPFVEEAERLRVQHKKDHPDYKYQPRRRK
       ..::.: : :::: ::: ::: :. :: .:::::::::::::::: .:::.:::.:::.:
NP_060 KRLAQQNPDLHNAVLSKMLGKAWKELNAAEKRPFVEEAERLRVQHLRDHPNYKYRPRRKK
              110       120       130       140       150       160

              190       200       210       220        230         
pF1KB3 SVKNGQAEAEEATEQTHISPNAIFKALQADSPHSSSGMSEVHSPG-EHSGQSQGPPTPPT
       ......             :.   . . : :  :. .. :.   : : .:   : :::  
NP_060 QARKARRLEPGLLLPGLAPPQPPPEPFPAASG-SARAFRELPPLGAEFDGL--GLPTPER
              170       180       190        200       210         

     240       250       260       270       280       290         
pF1KB3 TPKTDVQPGKADLKREGRPLPEGGRQPPIDFRDVDIGELSSDVISNIETFDVNEFDQYLP
       .:   ..::.: .      .:     ::   .:  .  . .    .  . :         
NP_060 SPLDGLEPGEAAF------FP-----PPAAPEDCALRPFRAPYAPTELSRD---------
       220       230                  240       250                

     300       310       320       330         340       350       
pF1KB3 PNGHPGVPATHGQVTYTGSYGISSTAATPAS--AGHVWMSKQQAPPPPPQQPPQAPPAPQ
       :.:  :.: ...  :           : ::.  :: ....   .: : :   : .:: :.
NP_060 PGGCYGAPLAEALRT-----------APPAAPLAG-LYYGTLGTPGPYPG--PLSPP-PE
       260       270                  280        290         300   

       360       370       380       390       400       410       
pF1KB3 APPQPQAAPPQQPAAPPQQPQAHTLTTLSSEPGQSQRTHIKTEQLSPSHYSEQQQHSPQQ
       :::  ..: :  :::                                             
NP_060 APPL-ESAEPLGPAADLWADVDLTEFDQYLNCSRTRPDAPGLPYHVALAKLGPRAMSCPE
             310       320       330       340       350       360 

>>NP_009015 (OMIM: 604974) transcription factor SOX-21 [  (276 aa)
 initn: 422 init1: 396 opt: 423  Z-score: 195.0  bits: 44.8 E(85289): 0.0004
Smith-Waterman score: 433; 33.0% identity (57.2% similar) in 285 aa overlap (99-364:2-271)

       70        80        90       100       110       120        
pF1KB3 FPVCIREAVSQVLKGYDWTLVPMPVRVNGSSKNKPHVKRPMNAFMVWAQAARRKLADQYP
                                     ::   ::::::::::::..: :::.:.. :
NP_009                              MSKPVDHVKRPMNAFMVWSRAQRRKMAQENP
                                            10        20        30 

      130       140       150       160       170        180       
pF1KB3 HLHNAELSKTLGKLWRLLNESEKRPFVEEAERLRVQHKKDHPDYKYQPRRR-KSVKNGQA
       ..::.:.:: ::  :.::.:::::::..::.:::..: :.::::::.:::. :.. . . 
NP_009 KMHNSEISKRLGAEWKLLTESEKRPFIDEAKRLRAMHMKEHPDYKYRPRRKPKTLLKKDK
              40        50        60        70        80        90 

       190       200       210       220       230         240     
pF1KB3 EAEEATEQTHISPNAIFKALQADSPHSSSGMSEVHSPGEHSGQSQG--PPTPPTTPKTDV
        :  .       : ..  . .:. :  ..:       : :.: . :  : .  ..:.  .
NP_009 FAFPV-------PYGLGGVADAEHPALKAGA------GLHAGAGGGLVPESLLANPEKAA
                    100       110             120       130        

         250       260       270       280       290       300     
pF1KB3 QPGKADLKREGRPLPEGGRQPPIDFRDVDIGELSSDVISNIETFDVNEFDQYLPPN---G
         . :   :    .:...         .  :   : .  . .  ...  .. ::     :
NP_009 AAAAAAAARV--FFPQSAAAAAAAAAAAAAGSPYSLLDLGSKMAEISSSSSGLPYASSLG
      140         150       160       170       180       190      

              310            320       330       340       350     
pF1KB3 HP--GVPATHGQVTYTGSY-----GISSTAATPASAGHVWMSKQQAPPPPPQQPPQAP--
       .:  :. : :: .. ...      : . .  .:.. :..   . .: : :  ::: :   
NP_009 YPTAGAGAFHGAAAAAAAAAAAAGGHTHSHPSPGNPGYMIPCNCSAWPSPGLQPPLAYIL
        200       210       220       230       240       250      

               360       370       380       390       400         
pF1KB3 -PA---PQAPPQPQAAPPQQPAAPPQQPQAHTLTTLSSEPGQSQRTHIKTEQLSPSHYSE
        :.   ::  : : :                                             
NP_009 LPGMGKPQLDPYPAAYAAAL                                        
        260       270                                              

>>NP_008873 (OMIM: 601297) protein SOX-15 [Homo sapiens]  (233 aa)
 initn: 448 init1: 379 opt: 408  Z-score: 190.2  bits: 43.6 E(85289): 0.00074
Smith-Waterman score: 408; 40.9% identity (66.1% similar) in 171 aa overlap (105-266:49-218)

           80        90       100       110       120       130    
pF1KB3 EAVSQVLKGYDWTLVPMPVRVNGSSKNKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAE
                                     :::::::::::..: ::..:.: :..::.:
NP_008 ATAAASSSSGPQEREGAGSPAAPGTLPLEKVKRPMNAFMVWSSAQRRQMAQQNPKMHNSE
       20        30        40        50        60        70        

          140       150       160       170        180             
pF1KB3 LSKTLGKLWRLLNESEKRPFVEEAERLRVQHKKDHPDYKYQPRRR-KSV-----KNGQAE
       .:: ::  :.::.:.:::::::::.:::..: .:.:::::.:::. ::      . ::..
NP_008 ISKRLGAQWKLLDEDEKRPFVEEAKRLRARHLRDYPDYKYRPRRKAKSSGAGPSRCGQGR
       80        90       100       110       120       130        

      190       200       210       220       230          240     
pF1KB3 AEEATEQTHISPNAIFKALQADSPHSSSGMSEVHSPGEHSGQSQGP---PTPPTTPKTDV
       .. :.     .:.      .    .   ..: .. :: . :.:.     :.: . :..: 
NP_008 GNLASGGPLWGPGYATTQPSRGFGYRPPSYSTAYLPGSY-GSSHCKLEAPSPCSLPQSDP
      140       150       160       170        180       190       

         250       260       270       280       290       300     
pF1KB3 QPGKADLKREGRPLPEGGRQPPIDFRDVDIGELSSDVISNIETFDVNEFDQYLPPNGHPG
       .     :    . :: :.  :                                       
NP_008 RLQGELLPTYTHYLPPGSPTPYNPPLAGAPMPLTHL                        
       200       210       220       230                           

>>NP_004180 (OMIM: 604747) transcription factor SOX-14 [  (240 aa)
 initn: 393 init1: 393 opt: 405  Z-score: 188.9  bits: 43.4 E(85289): 0.00088
Smith-Waterman score: 405; 33.6% identity (61.9% similar) in 244 aa overlap (99-333:2-236)

       70        80        90       100       110       120        
pF1KB3 FPVCIREAVSQVLKGYDWTLVPMPVRVNGSSKNKPHVKRPMNAFMVWAQAARRKLADQYP
                                     :: . :.::::::::::... :::.:.. :
NP_004                              MSKPSDHIKRPMNAFMVWSRGQRRKMAQENP
                                            10        20        30 

      130       140       150       160       170       180        
pF1KB3 HLHNAELSKTLGKLWRLLNESEKRPFVEEAERLRVQHKKDHPDYKYQPRRRKSVKNGQAE
       ..::.:.:: ::  :.::.:.::::...::.:::.:: :.::::::.:::.   ::   .
NP_004 KMHNSEISKRLGAEWKLLSEAEKRPYIDEAKRLRAQHMKEHPDYKYRPRRKP--KNLLKK
              40        50        60        70        80           

      190       200       210        220       230       240       
pF1KB3 AEEATEQTHISPNAIFKALQADSP-HSSSGMSEVHSPGEHSGQSQGPPTPPTTPKTDVQP
        . .    ... .  .::  :  :  .:.:.  . .: :..     : . : .    .: 
NP_004 DRYVFPLPYLGDTDPLKA--AGLPVGASDGL--LSAP-EKARAFLPPASAPYSLLDPAQF
      90       100         110         120        130       140    

       250       260             270       280       290       300 
pF1KB3 GKADLKREGRPLPEG---GRQP---PIDFRDVDIGELSSDVISNIETFDVNEFDQYLPPN
       ... ... :. .:.    :  :    . ...  .: ::    .. .:        :. : 
NP_004 SSSAIQKMGE-VPHTLATGALPYASTLGYQNGAFGSLSCPS-QHTHTHPSPTNPGYVVPC
          150        160       170       180        190       200  

             310         320       330       340       350         
pF1KB3 GHPGVPATHGQ--VTYTGSYGISSTAATPASAGHVWMSKQQAPPPPPQQPPQAPPAPQAP
       .  .  :.  :  :.:    :...:.  : :..:                          
NP_004 NCTAWSASTLQPPVAYILFPGMTKTGIDPYSSAHATAM                      
            210       220       230       240                      

     360       370       380       390       400       410         
pF1KB3 PQPQAAPPQQPAAPPQQPQAHTLTTLSSEPGQSQRTHIKTEQLSPSHYSEQQQHSPQQIA

>>NP_003097 (OMIM: 184429,189960,206900) transcription f  (317 aa)
 initn: 398 init1: 372 opt: 407  Z-score: 188.1  bits: 43.7 E(85289): 0.00098
Smith-Waterman score: 407; 29.6% identity (58.8% similar) in 294 aa overlap (97-380:32-316)

         70        80        90       100        110       120     
pF1KB3 DKFPVCIREAVSQVLKGYDWTLVPMPVRVNGSSKNKP-HVKRPMNAFMVWAQAARRKLAD
                                     :..::.: .:::::::::::... :::.:.
NP_003 YNMMETELKPPGPQQTSGGGGGNSTAAAAGGNQKNSPDRVKRPMNAFMVWSRGQRRKMAQ
              10        20        30        40        50        60 

         130       140       150       160       170       180     
pF1KB3 QYPHLHNAELSKTLGKLWRLLNESEKRPFVEEAERLRVQHKKDHPDYKYQPRRRKSVKNG
       . :..::.:.:: ::  :.::.:.:::::..::.:::. : :.::::::.:::.  .:. 
NP_003 ENPKMHNSEISKRLGAEWKLLSETEKRPFIDEAKRLRALHMKEHPDYKYRPRRK--TKTL
              70        80        90       100       110           

         190       200         210       220       230       240   
pF1KB3 QAEAEEATEQTHISP--NAIFKALQADSPHSSSGMSEVHSPGEHSGQSQGPPTPPTTPKT
       . . . .     ..:  :.. ... . .  ...  ... : .. .: :.:  .       
NP_003 MKKDKYTLPGGLLAPGGNSMASGVGVGAGLGAGVNQRMDSYAHMNGWSNG--SYSMMQDQ
     120       130       140       150       160         170       

           250       260       270       280       290       300   
pF1KB3 DVQPGKADLKREGRPLPEGGRQPPIDFRDVDIGELSSDVISNIETFDVNEFDQYLPPNGH
          : .  :. .:     .... :.   ::.  . .: . :.        ...    .: 
NP_003 LGYPQHPGLNAHG-----AAQMQPMHRYDVSALQYNSMTSSQTYMNGSPTYSMSYSQQGT
       180       190            200       210       220       230  

            310          320          330       340       350      
pF1KB3 PGVP-ATHGQVTYT---GSYGI---SSTAATPASAGHVWMSKQQAPPPPPQQPPQAPPAP
       ::.  .. :.:. .   .:  .   :: . .: .:: .    ..  :      : ::   
NP_003 PGMALGSMGSVVKSEASSSPPVVTSSSHSRAPCQAGDLRDMISMYLPGAEVPEPAAPSRL
            240       250       260       270       280       290  

        360       370       380       390       400       410      
pF1KB3 QAPPQPQAAPPQQPAAPPQQPQAHTLTTLSSEPGQSQRTHIKTEQLSPSHYSEQQQHSPQ
       .   . :..:    :     : .:                                    
NP_003 HMSQHYQSGPVPGTAINGTLPLSHM                                   
            300       310                                          




509 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 14:11:32 2016 done: Thu Nov  3 14:11:33 2016
 Total Scan time:  8.980 Total Display time:  0.030

Function used was FASTA [36.3.4 Apr, 2011]
Inquiries or Suggestions ?
Send a message to flexiclone AT kazusagt.com