FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3947, 888 aa
1>>>pF1KB3947 888 - 888 aa - 888 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.4314+/-0.00112; mu= 19.7358+/- 0.067
mean_var=61.7228+/-12.072, 0's: 0 Z-trim(101.4): 21 B-trim: 0 in 0/50
Lambda= 0.163249
statistics sampled from 6488 (6497) to 6488 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.55), E-opt: 0.2 (0.2), width: 16
Scan time: 3.920
The best scores are: opt bits E(32554)
CCDS4027.1 HMGCR gene_id:3156|Hs108|chr5 ( 888) 5804 1376.4 0
CCDS47234.1 HMGCR gene_id:3156|Hs108|chr5 ( 835) 3420 814.9 0
>>CCDS4027.1 HMGCR gene_id:3156|Hs108|chr5 (888 aa)
initn: 5804 init1: 5804 opt: 5804 Z-score: 7378.1 bits: 1376.4 E(32554): 0
Smith-Waterman score: 5804; 100.0% identity (100.0% similar) in 888 aa overlap (1-888:1-888)
10 20 30 40 50 60
pF1KB3 MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS40 MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 DIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS40 DIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 LNEALPFFLLLIDLSRASTLAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS40 LNEALPFFLLLIDLSRASTLAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 VGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS40 VGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFAR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 VLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTADTSKVSLGLDENVSKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS40 VLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTADTSKVSLGLDENVSKR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 IEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQTETESTLSLKNPITSPVVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS40 IEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQTETESTLSLKNPITSPVVT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 QKKVPDNCCRREPMLVRNNQKCDSVEEETGINRERKVEVIKPLVAETDTPNRATFVVGNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS40 QKKVPDNCCRREPMLVRNNQKCDSVEEETGINRERKVEVIKPLVAETDTPNRATFVVGNS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 SLLDTSSVLVTQEPEIELPREPRPNEECLQILGNAEKGAKFLSDAEIIQLVNAKHIPAYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS40 SLLDTSSVLVTQEPEIELPREPRPNEECLQILGNAEKGAKFLSDAEIIQLVNAKHIPAYK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 LETLMETHERGVSIRRQLLSKKLSEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS40 LETLMETHERGVSIRRQLLSKKLSEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGV
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 AGPLCLDEKEFQVPMATTEGCLVASTNRGCRAIGLGGGASSRVLADGMTRGPVVRLPRAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS40 AGPLCLDEKEFQVPMATTEGCLVASTNRGCRAIGLGGGASSRVLADGMTRGPVVRLPRAC
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 DSAEVKAWLETSEGFAVIKEAFDSTSRFARLQKLHTSIAGRNLYIRFQSRSGDAMGMNMI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS40 DSAEVKAWLETSEGFAVIKEAFDSTSRFARLQKLHTSIAGRNLYIRFQSRSGDAMGMNMI
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB3 SKGTEKALSKLHEYFPEMQILAVSGNYCTDKKPAAINWIEGRGKSVVCEAVIPAKVVREV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS40 SKGTEKALSKLHEYFPEMQILAVSGNYCTDKKPAAINWIEGRGKSVVCEAVIPAKVVREV
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB3 LKTTTEAMIEVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS40 LKTTTEAMIEVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITL
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB3 MEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS40 MEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLAR
790 800 810 820 830 840
850 860 870 880
pF1KB3 IVCGTVMAGELSLMAALAAGHLVKSHMIHNRSKINLQDLQGACTKKTA
::::::::::::::::::::::::::::::::::::::::::::::::
CCDS40 IVCGTVMAGELSLMAALAAGHLVKSHMIHNRSKINLQDLQGACTKKTA
850 860 870 880
>>CCDS47234.1 HMGCR gene_id:3156|Hs108|chr5 (835 aa)
initn: 3393 init1: 3393 opt: 3420 Z-score: 4344.1 bits: 814.9 E(32554): 0
Smith-Waterman score: 5312; 94.0% identity (94.0% similar) in 888 aa overlap (1-888:1-835)
10 20 30 40 50 60
pF1KB3 MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 DIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 DIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 LNEALPFFLLLIDLSRASTLAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 LNEALPFFLLLIDLSRASTLAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 VGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 VGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFAR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 VLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTADTSKVSLGLDENVSKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 VLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTADTSKVSLGLDENVSKR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 IEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQTETESTLSLKNPITSPVVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 IEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQTETESTLSLKNPITSPVVT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 QKKVPDNCCRREPMLVRNNQKCDSVEEETGINRERKVEVIKPLVAETDTPNRATFVVGNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 QKKVPDNCCRREPMLVRNNQKCDSVEEETGINRERKVEVIKPLVAETDTPNRATFVVGNS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 SLLDTSSVLVTQEPEIELPREPRPNEECLQILGNAEKGAKFLSDAEIIQLVNAKHIPAYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 SLLDTSSVLVTQEPEIELPREPRPNEECLQILGNAEKGAKFLSDAEIIQLVNAKHIPAYK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 LETLMETHERGVSIRRQLLSKKLSEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGV
:::::::::::::::::::::::::::::::::::::::::
CCDS47 LETLMETHERGVSIRRQLLSKKLSEPSSLQYLPYRDYNYSL-------------------
490 500 510 520
550 560 570 580 590 600
pF1KB3 AGPLCLDEKEFQVPMATTEGCLVASTNRGCRAIGLGGGASSRVLADGMTRGPVVRLPRAC
::::::::::::::::::::::::::
CCDS47 ----------------------------------LGGGASSRVLADGMTRGPVVRLPRAC
530 540
610 620 630 640 650 660
pF1KB3 DSAEVKAWLETSEGFAVIKEAFDSTSRFARLQKLHTSIAGRNLYIRFQSRSGDAMGMNMI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 DSAEVKAWLETSEGFAVIKEAFDSTSRFARLQKLHTSIAGRNLYIRFQSRSGDAMGMNMI
550 560 570 580 590 600
670 680 690 700 710 720
pF1KB3 SKGTEKALSKLHEYFPEMQILAVSGNYCTDKKPAAINWIEGRGKSVVCEAVIPAKVVREV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 SKGTEKALSKLHEYFPEMQILAVSGNYCTDKKPAAINWIEGRGKSVVCEAVIPAKVVREV
610 620 630 640 650 660
730 740 750 760 770 780
pF1KB3 LKTTTEAMIEVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 LKTTTEAMIEVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITL
670 680 690 700 710 720
790 800 810 820 830 840
pF1KB3 MEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 MEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLAR
730 740 750 760 770 780
850 860 870 880
pF1KB3 IVCGTVMAGELSLMAALAAGHLVKSHMIHNRSKINLQDLQGACTKKTA
::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 IVCGTVMAGELSLMAALAAGHLVKSHMIHNRSKINLQDLQGACTKKTA
790 800 810 820 830
888 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 07:10:46 2016 done: Sat Nov 5 07:10:46 2016
Total Scan time: 3.920 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]