FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3947, 888 aa 1>>>pF1KB3947 888 - 888 aa - 888 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.4314+/-0.00112; mu= 19.7358+/- 0.067 mean_var=61.7228+/-12.072, 0's: 0 Z-trim(101.4): 21 B-trim: 0 in 0/50 Lambda= 0.163249 statistics sampled from 6488 (6497) to 6488 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.55), E-opt: 0.2 (0.2), width: 16 Scan time: 3.920 The best scores are: opt bits E(32554) CCDS4027.1 HMGCR gene_id:3156|Hs108|chr5 ( 888) 5804 1376.4 0 CCDS47234.1 HMGCR gene_id:3156|Hs108|chr5 ( 835) 3420 814.9 0 >>CCDS4027.1 HMGCR gene_id:3156|Hs108|chr5 (888 aa) initn: 5804 init1: 5804 opt: 5804 Z-score: 7378.1 bits: 1376.4 E(32554): 0 Smith-Waterman score: 5804; 100.0% identity (100.0% similar) in 888 aa overlap (1-888:1-888) 10 20 30 40 50 60 pF1KB3 MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS40 MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 DIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS40 DIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 LNEALPFFLLLIDLSRASTLAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS40 LNEALPFFLLLIDLSRASTLAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 VGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS40 VGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFAR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 VLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTADTSKVSLGLDENVSKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS40 VLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTADTSKVSLGLDENVSKR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 IEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQTETESTLSLKNPITSPVVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS40 IEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQTETESTLSLKNPITSPVVT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 QKKVPDNCCRREPMLVRNNQKCDSVEEETGINRERKVEVIKPLVAETDTPNRATFVVGNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS40 QKKVPDNCCRREPMLVRNNQKCDSVEEETGINRERKVEVIKPLVAETDTPNRATFVVGNS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 SLLDTSSVLVTQEPEIELPREPRPNEECLQILGNAEKGAKFLSDAEIIQLVNAKHIPAYK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS40 SLLDTSSVLVTQEPEIELPREPRPNEECLQILGNAEKGAKFLSDAEIIQLVNAKHIPAYK 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 LETLMETHERGVSIRRQLLSKKLSEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS40 LETLMETHERGVSIRRQLLSKKLSEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGV 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB3 AGPLCLDEKEFQVPMATTEGCLVASTNRGCRAIGLGGGASSRVLADGMTRGPVVRLPRAC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS40 AGPLCLDEKEFQVPMATTEGCLVASTNRGCRAIGLGGGASSRVLADGMTRGPVVRLPRAC 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB3 DSAEVKAWLETSEGFAVIKEAFDSTSRFARLQKLHTSIAGRNLYIRFQSRSGDAMGMNMI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS40 DSAEVKAWLETSEGFAVIKEAFDSTSRFARLQKLHTSIAGRNLYIRFQSRSGDAMGMNMI 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB3 SKGTEKALSKLHEYFPEMQILAVSGNYCTDKKPAAINWIEGRGKSVVCEAVIPAKVVREV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS40 SKGTEKALSKLHEYFPEMQILAVSGNYCTDKKPAAINWIEGRGKSVVCEAVIPAKVVREV 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB3 LKTTTEAMIEVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS40 LKTTTEAMIEVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITL 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB3 MEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS40 MEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLAR 790 800 810 820 830 840 850 860 870 880 pF1KB3 IVCGTVMAGELSLMAALAAGHLVKSHMIHNRSKINLQDLQGACTKKTA :::::::::::::::::::::::::::::::::::::::::::::::: CCDS40 IVCGTVMAGELSLMAALAAGHLVKSHMIHNRSKINLQDLQGACTKKTA 850 860 870 880 >>CCDS47234.1 HMGCR gene_id:3156|Hs108|chr5 (835 aa) initn: 3393 init1: 3393 opt: 3420 Z-score: 4344.1 bits: 814.9 E(32554): 0 Smith-Waterman score: 5312; 94.0% identity (94.0% similar) in 888 aa overlap (1-888:1-835) 10 20 30 40 50 60 pF1KB3 MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 DIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 DIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 LNEALPFFLLLIDLSRASTLAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 LNEALPFFLLLIDLSRASTLAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 VGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 VGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFAR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 VLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTADTSKVSLGLDENVSKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 VLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTADTSKVSLGLDENVSKR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 IEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQTETESTLSLKNPITSPVVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 IEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQTETESTLSLKNPITSPVVT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 QKKVPDNCCRREPMLVRNNQKCDSVEEETGINRERKVEVIKPLVAETDTPNRATFVVGNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 QKKVPDNCCRREPMLVRNNQKCDSVEEETGINRERKVEVIKPLVAETDTPNRATFVVGNS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 SLLDTSSVLVTQEPEIELPREPRPNEECLQILGNAEKGAKFLSDAEIIQLVNAKHIPAYK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 SLLDTSSVLVTQEPEIELPREPRPNEECLQILGNAEKGAKFLSDAEIIQLVNAKHIPAYK 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB3 LETLMETHERGVSIRRQLLSKKLSEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGV ::::::::::::::::::::::::::::::::::::::::: CCDS47 LETLMETHERGVSIRRQLLSKKLSEPSSLQYLPYRDYNYSL------------------- 490 500 510 520 550 560 570 580 590 600 pF1KB3 AGPLCLDEKEFQVPMATTEGCLVASTNRGCRAIGLGGGASSRVLADGMTRGPVVRLPRAC :::::::::::::::::::::::::: CCDS47 ----------------------------------LGGGASSRVLADGMTRGPVVRLPRAC 530 540 610 620 630 640 650 660 pF1KB3 DSAEVKAWLETSEGFAVIKEAFDSTSRFARLQKLHTSIAGRNLYIRFQSRSGDAMGMNMI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 DSAEVKAWLETSEGFAVIKEAFDSTSRFARLQKLHTSIAGRNLYIRFQSRSGDAMGMNMI 550 560 570 580 590 600 670 680 690 700 710 720 pF1KB3 SKGTEKALSKLHEYFPEMQILAVSGNYCTDKKPAAINWIEGRGKSVVCEAVIPAKVVREV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 SKGTEKALSKLHEYFPEMQILAVSGNYCTDKKPAAINWIEGRGKSVVCEAVIPAKVVREV 610 620 630 640 650 660 730 740 750 760 770 780 pF1KB3 LKTTTEAMIEVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 LKTTTEAMIEVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITL 670 680 690 700 710 720 790 800 810 820 830 840 pF1KB3 MEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 MEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLAR 730 740 750 760 770 780 850 860 870 880 pF1KB3 IVCGTVMAGELSLMAALAAGHLVKSHMIHNRSKINLQDLQGACTKKTA :::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 IVCGTVMAGELSLMAALAAGHLVKSHMIHNRSKINLQDLQGACTKKTA 790 800 810 820 830 888 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 07:10:46 2016 done: Sat Nov 5 07:10:46 2016 Total Scan time: 3.920 Total Display time: 0.060 Function used was FASTA [36.3.4 Apr, 2011]