FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3951, 305 aa 1>>>pF1KB3951 305 - 305 aa - 305 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.9691+/-0.000365; mu= 16.9631+/- 0.023 mean_var=62.1643+/-12.940, 0's: 0 Z-trim(112.7): 49 B-trim: 996 in 1/54 Lambda= 0.162669 statistics sampled from 21646 (21698) to 21646 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.637), E-opt: 0.2 (0.254), width: 16 Scan time: 5.670 The best scores are: opt bits E(85289) NP_002712 (OMIM: 612725) serine/threonine-protein ( 305) 2131 508.8 5.6e-144 NP_001116827 (OMIM: 612725) serine/threonine-prote ( 342) 1963 469.4 4.5e-132 XP_011517149 (OMIM: 612725) PREDICTED: serine/thre ( 293) 1962 469.1 4.7e-132 NP_001116841 (OMIM: 612725) serine/threonine-prote ( 283) 1576 378.5 8.5e-105 NP_002711 (OMIM: 602035) serine/threonine-protein ( 307) 1373 330.9 2e-90 NP_001290432 (OMIM: 602035) serine/threonine-prote ( 307) 1373 330.9 2e-90 NP_001009552 (OMIM: 176916) serine/threonine-prote ( 309) 1257 303.7 3.1e-82 NP_002706 (OMIM: 176915) serine/threonine-protein ( 309) 1241 299.9 4.2e-81 XP_016878892 (OMIM: 602035) PREDICTED: serine/thre ( 228) 1053 255.7 6.3e-68 NP_001290436 (OMIM: 602035) serine/threonine-prote ( 228) 1053 255.7 6.3e-68 XP_016878893 (OMIM: 602035) PREDICTED: serine/thre ( 228) 1053 255.7 6.3e-68 NP_001290435 (OMIM: 602035) serine/threonine-prote ( 228) 1053 255.7 6.3e-68 XP_006721124 (OMIM: 602035) PREDICTED: serine/thre ( 273) 941 229.5 6e-60 NP_001290433 (OMIM: 602035) serine/threonine-prote ( 273) 941 229.5 6e-60 XP_011536807 (OMIM: 176914) PREDICTED: serine/thre ( 330) 918 224.1 2.9e-58 XP_011536806 (OMIM: 176914) PREDICTED: serine/thre ( 362) 917 223.9 3.7e-58 NP_001231903 (OMIM: 176914) serine/threonine-prote ( 337) 914 223.2 5.7e-58 NP_002701 (OMIM: 176914) serine/threonine-protein ( 323) 912 222.7 7.6e-58 NP_002699 (OMIM: 176875) serine/threonine-protein ( 330) 905 221.1 2.4e-57 NP_001008709 (OMIM: 176875) serine/threonine-prote ( 341) 905 221.1 2.5e-57 NP_996759 (OMIM: 600590) serine/threonine-protein ( 327) 864 211.4 1.9e-54 NP_002700 (OMIM: 600590) serine/threonine-protein ( 327) 864 211.4 1.9e-54 NP_996756 (OMIM: 176875) serine/threonine-protein ( 286) 846 207.2 3.2e-53 NP_006238 (OMIM: 600658) serine/threonine-protein ( 499) 708 175.0 2.8e-43 XP_016882424 (OMIM: 600658) PREDICTED: serine/thre ( 551) 703 173.8 6.8e-43 NP_001191213 (OMIM: 600658) serine/threonine-prote ( 477) 701 173.3 8.4e-43 NP_001124164 (OMIM: 114105) serine/threonine-prote ( 469) 676 167.4 4.9e-41 XP_016863854 (OMIM: 114105) PREDICTED: serine/thre ( 509) 676 167.4 5.2e-41 NP_001124163 (OMIM: 114105) serine/threonine-prote ( 511) 676 167.4 5.2e-41 NP_000935 (OMIM: 114105) serine/threonine-protein ( 521) 676 167.5 5.3e-41 XP_016871868 (OMIM: 114106) PREDICTED: serine/thre ( 426) 664 164.6 3.2e-40 XP_005270001 (OMIM: 114106) PREDICTED: serine/thre ( 514) 664 164.6 3.7e-40 NP_001135826 (OMIM: 114106) serine/threonine-prote ( 515) 664 164.6 3.7e-40 NP_066955 (OMIM: 114106) serine/threonine-protein ( 524) 664 164.6 3.7e-40 NP_001135825 (OMIM: 114106) serine/threonine-prote ( 525) 664 164.6 3.7e-40 NP_001276898 (OMIM: 114106) serine/threonine-prote ( 410) 657 162.9 9.6e-40 XP_016869100 (OMIM: 114107) PREDICTED: serine/thre ( 418) 653 162.0 1.9e-39 NP_001230904 (OMIM: 114107) serine/threonine-prote ( 502) 653 162.0 2.2e-39 NP_005596 (OMIM: 114107) serine/threonine-protein ( 512) 653 162.1 2.2e-39 NP_001230903 (OMIM: 114107) serine/threonine-prote ( 521) 653 162.1 2.2e-39 XP_016869099 (OMIM: 114107) PREDICTED: serine/thre ( 439) 644 159.9 8.4e-39 NP_006230 (OMIM: 602256) serine/threonine-protein ( 753) 358 92.9 2.1e-18 XP_011530341 (OMIM: 602256) PREDICTED: serine/thre ( 753) 358 92.9 2.1e-18 XP_016885101 (OMIM: 300109) PREDICTED: serine/thre ( 563) 294 77.8 5.5e-14 NP_689412 (OMIM: 300109) serine/threonine-protein ( 591) 294 77.8 5.7e-14 NP_689410 (OMIM: 300109) serine/threonine-protein ( 625) 294 77.9 5.9e-14 NP_006231 (OMIM: 300109) serine/threonine-protein ( 653) 294 77.9 6.2e-14 XP_005274610 (OMIM: 300109) PREDICTED: serine/thre ( 653) 294 77.9 6.2e-14 NP_001276897 (OMIM: 114106) serine/threonine-prote ( 514) 243 65.8 2e-10 >>NP_002712 (OMIM: 612725) serine/threonine-protein phos (305 aa) initn: 2131 init1: 2131 opt: 2131 Z-score: 2705.9 bits: 508.8 E(85289): 5.6e-144 Smith-Waterman score: 2131; 100.0% identity (100.0% similar) in 305 aa overlap (1-305:1-305) 10 20 30 40 50 60 pF1KB3 MAPLDLDKYVEIARLCKYLPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQFYD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MAPLDLDKYVEIARLCKYLPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQFYD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 LCELFRTGGQVPDTNYIFMGDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 LCELFRTGGQVPDTNYIFMGDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQIT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 QVYGFYDECQTKYGNANAWRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 QVYGFYDECQTKYGNANAWRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 RNQEIPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 RNQEIPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 HEGYKFMFDEKLVTVWSAPNYCYRCGNIASIMVFKDVNTREPKLFRAVPDSERVIPPRTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 HEGYKFMFDEKLVTVWSAPNYCYRCGNIASIMVFKDVNTREPKLFRAVPDSERVIPPRTT 250 260 270 280 290 300 pF1KB3 TPYFL ::::: NP_002 TPYFL >>NP_001116827 (OMIM: 612725) serine/threonine-protein p (342 aa) initn: 1963 init1: 1963 opt: 1963 Z-score: 2492.1 bits: 469.4 E(85289): 4.5e-132 Smith-Waterman score: 2012; 89.0% identity (89.0% similar) in 337 aa overlap (6-305:6-342) 10 20 pF1KB3 MAPLDLDKYVEIARLCKYLPENDLK----------------------------------- :::::::::::::::::::: NP_001 MAPLDLDKYVEIARLCKYLPENDLKVSPICGLAPSGCGAPAGRPFLSPGPPPVFHFLRFL 10 20 30 40 50 60 30 40 50 60 70 80 pF1KB3 --RLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQFYDLCELFRTGGQVPDTNYIFMGDFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KERLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQFYDLCELFRTGGQVPDTNYIFMGDFV 70 80 90 100 110 120 90 100 110 120 130 140 pF1KB3 DRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANAWRYCT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANAWRYCT 130 140 150 160 170 180 150 160 170 180 190 200 pF1KB3 KVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDPEDVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDPEDVD 190 200 210 220 230 240 210 220 230 240 250 260 pF1KB3 TWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDEKLVTVWSAPNYCY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDEKLVTVWSAPNYCY 250 260 270 280 290 300 270 280 290 300 pF1KB3 RCGNIASIMVFKDVNTREPKLFRAVPDSERVIPPRTTTPYFL :::::::::::::::::::::::::::::::::::::::::: NP_001 RCGNIASIMVFKDVNTREPKLFRAVPDSERVIPPRTTTPYFL 310 320 330 340 >>XP_011517149 (OMIM: 612725) PREDICTED: serine/threonin (293 aa) initn: 1962 init1: 1962 opt: 1962 Z-score: 2491.8 bits: 469.1 E(85289): 4.7e-132 Smith-Waterman score: 1962; 100.0% identity (100.0% similar) in 280 aa overlap (26-305:14-293) 10 20 30 40 50 60 pF1KB3 MAPLDLDKYVEIARLCKYLPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQFYD ::::::::::::::::::::::::::::::::::: XP_011 MFLLPRLQLLGQMRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQFYD 10 20 30 40 70 80 90 100 110 120 pF1KB3 LCELFRTGGQVPDTNYIFMGDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LCELFRTGGQVPDTNYIFMGDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQIT 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB3 QVYGFYDECQTKYGNANAWRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QVYGFYDECQTKYGNANAWRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIE 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB3 RNQEIPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RNQEIPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLV 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB3 HEGYKFMFDEKLVTVWSAPNYCYRCGNIASIMVFKDVNTREPKLFRAVPDSERVIPPRTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HEGYKFMFDEKLVTVWSAPNYCYRCGNIASIMVFKDVNTREPKLFRAVPDSERVIPPRTT 230 240 250 260 270 280 pF1KB3 TPYFL ::::: XP_011 TPYFL 290 >>NP_001116841 (OMIM: 612725) serine/threonine-protein p (283 aa) initn: 1958 init1: 1576 opt: 1576 Z-score: 2002.5 bits: 378.5 E(85289): 8.5e-105 Smith-Waterman score: 1918; 92.8% identity (92.8% similar) in 305 aa overlap (1-305:1-283) 10 20 30 40 50 60 pF1KB3 MAPLDLDKYVEIARLCKYLPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQFYD ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAPLDLDKYVEIARLCKYLPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQ--- 10 20 30 40 50 70 80 90 100 110 120 pF1KB3 LCELFRTGGQVPDTNYIFMGDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQIT ::::::::::::::::::::::::::::::::::::::::: NP_001 -------------------GDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQIT 60 70 80 90 130 140 150 160 170 180 pF1KB3 QVYGFYDECQTKYGNANAWRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QVYGFYDECQTKYGNANAWRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIE 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB3 RNQEIPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RNQEIPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLV 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB3 HEGYKFMFDEKLVTVWSAPNYCYRCGNIASIMVFKDVNTREPKLFRAVPDSERVIPPRTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HEGYKFMFDEKLVTVWSAPNYCYRCGNIASIMVFKDVNTREPKLFRAVPDSERVIPPRTT 220 230 240 250 260 270 pF1KB3 TPYFL ::::: NP_001 TPYFL 280 >>NP_002711 (OMIM: 602035) serine/threonine-protein phos (307 aa) initn: 1404 init1: 1365 opt: 1373 Z-score: 1744.5 bits: 330.9 E(85289): 2e-90 Smith-Waterman score: 1373; 61.6% identity (85.0% similar) in 307 aa overlap (1-305:1-307) 10 20 30 40 50 pF1KB3 MAPL-DLDKYVEIARLCKYLPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQFY :: . :::. .: : :. . :...: :: . ..:.:::::: :..::::::::::::: NP_002 MAEISDLDRQIEQLRRCELIKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFY 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB3 DLCELFRTGGQVPDTNYIFMGDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQI :: ::::.::.::.:::.:::::::::.::.::: :::::...::::::.::::::::: NP_002 DLKELFRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQI 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB3 TQVYGFYDECQTKYGNANAWRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTI :::::::::: :::....:::::..::.:...:.:: .:.::::::::.:.:::::::: NP_002 TQVYGFYDECLRKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTI 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB3 ERNQEIPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQL .:.::.:: : .:::.::::::. :..::::::.:::. :. .: :.. .::::::: NP_002 DRKQEVPHDGPMCDLLWSDPEDTTGWGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQL 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB3 VHEGYKFMFDEKLVTVWSAPNYCYRCGNIASIMVFKDVNTREPKLFRAVPDSERVIPPRT : ::::. :.: ..::::::::::::::.:.:. . . .. .:.:.:. : :: . NP_002 VMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKDFIIFEAAPQETRGIPSKK 250 260 270 280 290 300 300 pF1KB3 -TTPYFL .. ::: NP_002 PVADYFL >>NP_001290432 (OMIM: 602035) serine/threonine-protein p (307 aa) initn: 1404 init1: 1365 opt: 1373 Z-score: 1744.5 bits: 330.9 E(85289): 2e-90 Smith-Waterman score: 1373; 61.6% identity (85.0% similar) in 307 aa overlap (1-305:1-307) 10 20 30 40 50 pF1KB3 MAPL-DLDKYVEIARLCKYLPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQFY :: . :::. .: : :. . :...: :: . ..:.:::::: :..::::::::::::: NP_001 MAEISDLDRQIEQLRRCELIKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFY 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB3 DLCELFRTGGQVPDTNYIFMGDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQI :: ::::.::.::.:::.:::::::::.::.::: :::::...::::::.::::::::: NP_001 DLKELFRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQI 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB3 TQVYGFYDECQTKYGNANAWRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTI :::::::::: :::....:::::..::.:...:.:: .:.::::::::.:.:::::::: NP_001 TQVYGFYDECLRKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTI 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB3 ERNQEIPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQL .:.::.:: : .:::.::::::. :..::::::.:::. :. .: :.. .::::::: NP_001 DRKQEVPHDGPMCDLLWSDPEDTTGWGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQL 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB3 VHEGYKFMFDEKLVTVWSAPNYCYRCGNIASIMVFKDVNTREPKLFRAVPDSERVIPPRT : ::::. :.: ..::::::::::::::.:.:. . . .. .:.:.:. : :: . NP_001 VMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKDFIIFEAAPQETRGIPSKK 250 260 270 280 290 300 300 pF1KB3 -TTPYFL .. ::: NP_001 PVADYFL >>NP_001009552 (OMIM: 176916) serine/threonine-protein p (309 aa) initn: 1256 init1: 1256 opt: 1257 Z-score: 1597.3 bits: 303.7 E(85289): 3.1e-82 Smith-Waterman score: 1257; 59.1% identity (80.2% similar) in 303 aa overlap (5-305:9-309) 10 20 30 40 50 pF1KB3 MAPLDLDKYVEIARLCKYLPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHG .::..:: :: : ::... ::. . ..: .::::: : :::::::.:: NP_001 MDDKAFTKELDQWVEQLNECKQLNENQVRTLCEKAKEILTKESNVQEVRCPVTVCGDVHG 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB3 QFYDLCELFRTGGQVPDTNYIFMGDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHES ::.:: :::: ::. :::::.::::.:::::::.:: : :.:::...:.:::.::::::: NP_001 QFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYPERITILRGNHES 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB3 RQITQVYGFYDECQTKYGNANAWRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQI ::::::::::::: ::::::.:.: : .::.: ..::.: ::.:.::::::.: :::.: NP_001 RQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHI 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB3 RTIERNQEIPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAKVTNEFVHINNLKLICRA :...: ::.::.: .:::.::::.: :.:::::::. :: ... : : :.: :. :: NP_001 RALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRA 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB3 HQLVHEGYKFMFDEKLVTVWSAPNYCYRCGNIASIMVFKDVNTREPKLFRAVPDSERVIP :::: :::.. :...::..::::::::::: :.:: . : : . .... : .: : NP_001 HQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDD--TLKYSFLQFDPAPRRGEP 250 260 270 280 290 300 pF1KB3 --PRTTTPYFL : : ::: NP_001 HVTRRTPDYFL 300 >>NP_002706 (OMIM: 176915) serine/threonine-protein phos (309 aa) initn: 1240 init1: 1240 opt: 1241 Z-score: 1577.0 bits: 299.9 E(85289): 4.2e-81 Smith-Waterman score: 1241; 58.4% identity (79.9% similar) in 303 aa overlap (5-305:9-309) 10 20 30 40 50 pF1KB3 MAPLDLDKYVEIARLCKYLPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHG .::...: :: : :...: ::. . ..: .::::: : :::::::.:: NP_002 MDEKVFTKELDQWIEQLNECKQLSESQVKSLCEKAKEILTKESNVQEVRCPVTVCGDVHG 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB3 QFYDLCELFRTGGQVPDTNYIFMGDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHES ::.:: :::: ::. :::::.::::.:::::::.:: : :.:::... .:::.::::::: NP_002 QFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYRERITILRGNHES 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB3 RQITQVYGFYDECQTKYGNANAWRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQI ::::::::::::: ::::::.:.: : .::.: ..::.: ::.:.::::::.: :::.: NP_002 RQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHI 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB3 RTIERNQEIPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAKVTNEFVHINNLKLICRA :...: ::.::.: .:::.::::.: :.:::::::. :: ... : : :.: :. :: NP_002 RALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRA 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB3 HQLVHEGYKFMFDEKLVTVWSAPNYCYRCGNIASIMVFKDVNTREPKLFRAVPDSERVIP :::: :::.. :...::..::::::::::: :.:: . : : . .... : .: : NP_002 HQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDD--TLKYSFLQFDPAPRRGEP 250 260 270 280 290 300 pF1KB3 --PRTTTPYFL : : ::: NP_002 HVTRRTPDYFL 300 >>XP_016878892 (OMIM: 602035) PREDICTED: serine/threonin (228 aa) initn: 1085 init1: 1046 opt: 1053 Z-score: 1340.5 bits: 255.7 E(85289): 6.3e-68 Smith-Waterman score: 1053; 62.3% identity (86.0% similar) in 228 aa overlap (79-305:1-228) 50 60 70 80 90 100 pF1KB3 TVCGDIHGQFYDLCELFRTGGQVPDTNYIFMGDFVDRGYYSLETFTYLLALKAKWPDRIT ::::::::.::.::: :::::...::::: XP_016 MGDFVDRGFYSVETFLLLLALKVRYPDRIT 10 20 30 110 120 130 140 150 160 pF1KB3 LLRGNHESRQITQVYGFYDECQTKYGNANAWRYCTKVFDMLTVAALIDEQILCVHGGLSP :.::::::::::::::::::: :::....:::::..::.:...:.:: .:.:::::::: XP_016 LIRGNHESRQITQVYGFYDECLRKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSP 40 50 60 70 80 90 170 180 190 200 210 220 pF1KB3 DIKTLDQIRTIERNQEIPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAKVTNEFVHIN .:.::::::::.:.::.:: : .:::.::::::. :..::::::.:::. :. .: : XP_016 SIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPEDTTGWGVSPRGAGYLFGSDVVAQFNAAN 100 110 120 130 140 150 230 240 250 260 270 280 pF1KB3 NLKLICRAHQLVHEGYKFMFDEKLVTVWSAPNYCYRCGNIASIMVFKDVNTREPKLFRAV .. .:::::::: ::::. :.: ..::::::::::::::.:.:. . . .. .:.:. XP_016 DIDMICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKDFIIFEAA 160 170 180 190 200 210 290 300 pF1KB3 PDSERVIPPRT-TTPYFL :. : :: . .. ::: XP_016 PQETRGIPSKKPVADYFL 220 >>NP_001290436 (OMIM: 602035) serine/threonine-protein p (228 aa) initn: 1085 init1: 1046 opt: 1053 Z-score: 1340.5 bits: 255.7 E(85289): 6.3e-68 Smith-Waterman score: 1053; 62.3% identity (86.0% similar) in 228 aa overlap (79-305:1-228) 50 60 70 80 90 100 pF1KB3 TVCGDIHGQFYDLCELFRTGGQVPDTNYIFMGDFVDRGYYSLETFTYLLALKAKWPDRIT ::::::::.::.::: :::::...::::: NP_001 MGDFVDRGFYSVETFLLLLALKVRYPDRIT 10 20 30 110 120 130 140 150 160 pF1KB3 LLRGNHESRQITQVYGFYDECQTKYGNANAWRYCTKVFDMLTVAALIDEQILCVHGGLSP :.::::::::::::::::::: :::....:::::..::.:...:.:: .:.:::::::: NP_001 LIRGNHESRQITQVYGFYDECLRKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSP 40 50 60 70 80 90 170 180 190 200 210 220 pF1KB3 DIKTLDQIRTIERNQEIPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAKVTNEFVHIN .:.::::::::.:.::.:: : .:::.::::::. :..::::::.:::. :. .: : NP_001 SIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPEDTTGWGVSPRGAGYLFGSDVVAQFNAAN 100 110 120 130 140 150 230 240 250 260 270 280 pF1KB3 NLKLICRAHQLVHEGYKFMFDEKLVTVWSAPNYCYRCGNIASIMVFKDVNTREPKLFRAV .. .:::::::: ::::. :.: ..::::::::::::::.:.:. . . .. .:.:. NP_001 DIDMICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKDFIIFEAA 160 170 180 190 200 210 290 300 pF1KB3 PDSERVIPPRT-TTPYFL :. : :: . .. ::: NP_001 PQETRGIPSKKPVADYFL 220 305 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 21:15:58 2016 done: Thu Nov 3 21:15:59 2016 Total Scan time: 5.670 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]