Result of FASTA (omim) for
pF1KB3956
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3956, 384 aa
1>>>pF1KB3956 384 - 384 aa - 384 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.9849+/-0.000481; mu= 18.3717+/- 0.030
mean_var=111.2115+/-29.075, 0's: 0 Z-trim(108.7): 622 B-trim: 840 in 1/53
Lambda= 0.121618
statistics sampled from 16100 (16845) to 16100 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.542), E-opt: 0.2 (0.198), width: 16
Scan time: 7.500
The best scores are: opt bits E(85289)
NP_658986 (OMIM: 244200,607123) prokineticin recep ( 384) 2560 461.1 2e-129
XP_016883135 (OMIM: 244200,607123) PREDICTED: prok ( 384) 2560 461.1 2e-129
XP_011527461 (OMIM: 244200,607123) PREDICTED: prok ( 348) 2306 416.5 4.9e-116
NP_620414 (OMIM: 607122) prokineticin receptor 1 [ ( 393) 2258 408.1 1.8e-113
XP_005263090 (OMIM: 162642) PREDICTED: neuropeptid ( 381) 530 104.9 3.3e-22
NP_000901 (OMIM: 162642) neuropeptide Y receptor t ( 381) 530 104.9 3.3e-22
XP_005263091 (OMIM: 162642) PREDICTED: neuropeptid ( 381) 530 104.9 3.3e-22
NP_004239 (OMIM: 600895) prolactin-releasing pepti ( 370) 496 98.9 2e-20
NP_001049 (OMIM: 162323) substance-P receptor isof ( 407) 478 95.8 1.9e-19
NP_056542 (OMIM: 162323) substance-P receptor isof ( 311) 475 95.1 2.3e-19
NP_057624 (OMIM: 605569) probable G-protein couple ( 423) 456 92.0 2.8e-18
NP_001048 (OMIM: 162321) substance-K receptor [Hom ( 398) 455 91.8 3.1e-18
NP_937822 (OMIM: 606925) pyroglutamylated RFamide ( 431) 446 90.2 9.7e-18
NP_001050 (OMIM: 162332,614840) neuromedin-K recep ( 465) 435 88.3 3.9e-17
NP_000900 (OMIM: 162641) neuropeptide Y receptor t ( 384) 432 87.7 5e-17
XP_005263088 (OMIM: 162641) PREDICTED: neuropeptid ( 384) 432 87.7 5e-17
XP_011530312 (OMIM: 162641) PREDICTED: neuropeptid ( 384) 432 87.7 5e-17
NP_005305 (OMIM: 305670) gastrin-releasing peptide ( 384) 427 86.8 9.1e-17
NP_071429 (OMIM: 607448) neuropeptide FF receptor ( 430) 421 85.8 2e-16
NP_001718 (OMIM: 300107) bombesin receptor subtype ( 399) 417 85.1 3.1e-16
NP_001517 (OMIM: 602393) orexin receptor type 2 [H ( 444) 415 84.8 4.3e-16
XP_016866287 (OMIM: 602393) PREDICTED: orexin rece ( 461) 415 84.8 4.4e-16
XP_016871876 (OMIM: 601790) PREDICTED: neuropeptid ( 375) 403 82.6 1.7e-15
NP_005963 (OMIM: 601790) neuropeptide Y receptor t ( 375) 403 82.6 1.7e-15
XP_016871875 (OMIM: 601790) PREDICTED: neuropeptid ( 375) 403 82.6 1.7e-15
XP_011538238 (OMIM: 601790) PREDICTED: neuropeptid ( 375) 403 82.6 1.7e-15
XP_011538239 (OMIM: 601790) PREDICTED: neuropeptid ( 375) 403 82.6 1.7e-15
NP_001265723 (OMIM: 601790) neuropeptide Y recepto ( 375) 403 82.6 1.7e-15
NP_001043 (OMIM: 182454) somatostatin receptor typ ( 388) 401 82.3 2.2e-15
NP_002502 (OMIM: 162341) neuromedin-B receptor iso ( 390) 401 82.3 2.2e-15
NP_444264 (OMIM: 607449) neuropeptide FF receptor ( 420) 388 80.0 1.1e-14
NP_001138228 (OMIM: 607449) neuropeptide FF recept ( 423) 388 80.0 1.1e-14
NP_004876 (OMIM: 607449) neuropeptide FF receptor ( 522) 388 80.2 1.3e-14
XP_016856596 (OMIM: 602392) PREDICTED: orexin rece ( 389) 386 79.6 1.3e-14
XP_016856594 (OMIM: 602392) PREDICTED: orexin rece ( 425) 386 79.7 1.4e-14
NP_001516 (OMIM: 602392) orexin receptor type 1 [H ( 425) 386 79.7 1.4e-14
XP_016856595 (OMIM: 602392) PREDICTED: orexin rece ( 425) 386 79.7 1.4e-14
NP_000903 (OMIM: 165196) kappa-type opioid recepto ( 380) 378 78.2 3.5e-14
NP_001305426 (OMIM: 165196) kappa-type opioid rece ( 409) 378 78.3 3.7e-14
NP_001471 (OMIM: 600377) galanin receptor type 1 [ ( 349) 377 78.0 3.8e-14
NP_001040 (OMIM: 182451) somatostatin receptor typ ( 391) 371 77.0 8.4e-14
NP_003605 (OMIM: 603692) galanin receptor type 3 [ ( 368) 352 73.7 8.1e-13
NP_005277 (OMIM: 600731) neuropeptides B/W recepto ( 333) 351 73.4 8.6e-13
NP_001008503 (OMIM: 600018) mu-type opioid recepto ( 418) 351 73.5 9.9e-13
NP_001138758 (OMIM: 600018) mu-type opioid recepto ( 420) 349 73.2 1.3e-12
NP_001138756 (OMIM: 600018) mu-type opioid recepto ( 403) 348 73.0 1.4e-12
NP_115940 (OMIM: 176400,604161,614837) kiSS-1 rece ( 398) 347 72.8 1.6e-12
NP_001138757 (OMIM: 600018) mu-type opioid recepto ( 389) 346 72.6 1.7e-12
NP_001008504 (OMIM: 600018) mu-type opioid recepto ( 392) 346 72.6 1.8e-12
NP_001138755 (OMIM: 600018) mu-type opioid recepto ( 397) 346 72.6 1.8e-12
>>NP_658986 (OMIM: 244200,607123) prokineticin receptor (384 aa)
initn: 2560 init1: 2560 opt: 2560 Z-score: 2444.6 bits: 461.1 E(85289): 2e-129
Smith-Waterman score: 2560; 100.0% identity (100.0% similar) in 384 aa overlap (1-384:1-384)
10 20 30 40 50 60
pF1KB3 MAAQNGNTSFTPNFNPPQDHASSLSFNFSYGDYDLPMDEDEDMTKTRTFFAAKIVIGIAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_658 MAAQNGNTSFTPNFNPPQDHASSLSFNFSYGDYDLPMDEDEDMTKTRTFFAAKIVIGIAL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 AGIMLVCGIGNFVFIAALTRYKKLRNLTNLLIANLAISDFLVAIICCPFEMDYYVVRQLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_658 AGIMLVCGIGNFVFIAALTRYKKLRNLTNLLIANLAISDFLVAIICCPFEMDYYVVRQLS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 WEHGHVLCASVNYLRTVSLYVSTNALLAIAIDRYLAIVHPLKPRMNYQTASFLIALVWMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_658 WEHGHVLCASVNYLRTVSLYVSTNALLAIAIDRYLAIVHPLKPRMNYQTASFLIALVWMV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 SILIAIPSAYFATETVLFIVKSQEKIFCGQIWPVDQQLYYKSYFLFIFGVEFVGPVVTMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_658 SILIAIPSAYFATETVLFIVKSQEKIFCGQIWPVDQQLYYKSYFLFIFGVEFVGPVVTMT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 LCYARISRELWFKAVPGFQTEQIRKRLRCRRKTVLVLMCILTAYVLCWAPFYGFTIVRDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_658 LCYARISRELWFKAVPGFQTEQIRKRLRCRRKTVLVLMCILTAYVLCWAPFYGFTIVRDF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 FPTVFVKEKHYLTAFYVVECIAMSNSMINTVCFVTVKNNTMKYFKKMMLLHWRPSQRGSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_658 FPTVFVKEKHYLTAFYVVECIAMSNSMINTVCFVTVKNNTMKYFKKMMLLHWRPSQRGSK
310 320 330 340 350 360
370 380
pF1KB3 SSADLDLRTNGVPTTEEVDCIRLK
::::::::::::::::::::::::
NP_658 SSADLDLRTNGVPTTEEVDCIRLK
370 380
>>XP_016883135 (OMIM: 244200,607123) PREDICTED: prokinet (384 aa)
initn: 2560 init1: 2560 opt: 2560 Z-score: 2444.6 bits: 461.1 E(85289): 2e-129
Smith-Waterman score: 2560; 100.0% identity (100.0% similar) in 384 aa overlap (1-384:1-384)
10 20 30 40 50 60
pF1KB3 MAAQNGNTSFTPNFNPPQDHASSLSFNFSYGDYDLPMDEDEDMTKTRTFFAAKIVIGIAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAAQNGNTSFTPNFNPPQDHASSLSFNFSYGDYDLPMDEDEDMTKTRTFFAAKIVIGIAL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 AGIMLVCGIGNFVFIAALTRYKKLRNLTNLLIANLAISDFLVAIICCPFEMDYYVVRQLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AGIMLVCGIGNFVFIAALTRYKKLRNLTNLLIANLAISDFLVAIICCPFEMDYYVVRQLS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 WEHGHVLCASVNYLRTVSLYVSTNALLAIAIDRYLAIVHPLKPRMNYQTASFLIALVWMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WEHGHVLCASVNYLRTVSLYVSTNALLAIAIDRYLAIVHPLKPRMNYQTASFLIALVWMV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 SILIAIPSAYFATETVLFIVKSQEKIFCGQIWPVDQQLYYKSYFLFIFGVEFVGPVVTMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SILIAIPSAYFATETVLFIVKSQEKIFCGQIWPVDQQLYYKSYFLFIFGVEFVGPVVTMT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 LCYARISRELWFKAVPGFQTEQIRKRLRCRRKTVLVLMCILTAYVLCWAPFYGFTIVRDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LCYARISRELWFKAVPGFQTEQIRKRLRCRRKTVLVLMCILTAYVLCWAPFYGFTIVRDF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 FPTVFVKEKHYLTAFYVVECIAMSNSMINTVCFVTVKNNTMKYFKKMMLLHWRPSQRGSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FPTVFVKEKHYLTAFYVVECIAMSNSMINTVCFVTVKNNTMKYFKKMMLLHWRPSQRGSK
310 320 330 340 350 360
370 380
pF1KB3 SSADLDLRTNGVPTTEEVDCIRLK
::::::::::::::::::::::::
XP_016 SSADLDLRTNGVPTTEEVDCIRLK
370 380
>>XP_011527461 (OMIM: 244200,607123) PREDICTED: prokinet (348 aa)
initn: 2306 init1: 2306 opt: 2306 Z-score: 2204.2 bits: 416.5 E(85289): 4.9e-116
Smith-Waterman score: 2306; 100.0% identity (100.0% similar) in 348 aa overlap (37-384:1-348)
10 20 30 40 50 60
pF1KB3 NTSFTPNFNPPQDHASSLSFNFSYGDYDLPMDEDEDMTKTRTFFAAKIVIGIALAGIMLV
::::::::::::::::::::::::::::::
XP_011 MDEDEDMTKTRTFFAAKIVIGIALAGIMLV
10 20 30
70 80 90 100 110 120
pF1KB3 CGIGNFVFIAALTRYKKLRNLTNLLIANLAISDFLVAIICCPFEMDYYVVRQLSWEHGHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CGIGNFVFIAALTRYKKLRNLTNLLIANLAISDFLVAIICCPFEMDYYVVRQLSWEHGHV
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB3 LCASVNYLRTVSLYVSTNALLAIAIDRYLAIVHPLKPRMNYQTASFLIALVWMVSILIAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LCASVNYLRTVSLYVSTNALLAIAIDRYLAIVHPLKPRMNYQTASFLIALVWMVSILIAI
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB3 PSAYFATETVLFIVKSQEKIFCGQIWPVDQQLYYKSYFLFIFGVEFVGPVVTMTLCYARI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSAYFATETVLFIVKSQEKIFCGQIWPVDQQLYYKSYFLFIFGVEFVGPVVTMTLCYARI
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB3 SRELWFKAVPGFQTEQIRKRLRCRRKTVLVLMCILTAYVLCWAPFYGFTIVRDFFPTVFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SRELWFKAVPGFQTEQIRKRLRCRRKTVLVLMCILTAYVLCWAPFYGFTIVRDFFPTVFV
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB3 KEKHYLTAFYVVECIAMSNSMINTVCFVTVKNNTMKYFKKMMLLHWRPSQRGSKSSADLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KEKHYLTAFYVVECIAMSNSMINTVCFVTVKNNTMKYFKKMMLLHWRPSQRGSKSSADLD
280 290 300 310 320 330
370 380
pF1KB3 LRTNGVPTTEEVDCIRLK
::::::::::::::::::
XP_011 LRTNGVPTTEEVDCIRLK
340
>>NP_620414 (OMIM: 607122) prokineticin receptor 1 [Homo (393 aa)
initn: 2258 init1: 2258 opt: 2258 Z-score: 2158.1 bits: 408.1 E(85289): 1.8e-113
Smith-Waterman score: 2258; 87.4% identity (95.5% similar) in 382 aa overlap (3-384:12-393)
10 20 30 40 50
pF1KB3 MAAQNGNTSFTPNFNPPQDHASSLSFNFSYGDYDLPMDEDEDMTKTRTFFA
: : .::: .:: ::.:. :::::.:::.:.:::::.:..:::::
NP_620 METTMGFMDDNATNTSTSFLSVLNPHGAHATSFPFNFSYSDYDMPLDEDEDVTNSRTFFA
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB3 AKIVIGIALAGIMLVCGIGNFVFIAALTRYKKLRNLTNLLIANLAISDFLVAIICCPFEM
::::::.::.:::::::::::.:::::.:::::::::::::::::::::::::.::::::
NP_620 AKIVIGMALVGIMLVCGIGNFIFIAALVRYKKLRNLTNLLIANLAISDFLVAIVCCPFEM
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB3 DYYVVRQLSWEHGHVLCASVNYLRTVSLYVSTNALLAIAIDRYLAIVHPLKPRMNYQTAS
:::::::::::::::::.::::::::::::::::::::::::::::::::.:::. :::.
NP_620 DYYVVRQLSWEHGHVLCTSVNYLRTVSLYVSTNALLAIAIDRYLAIVHPLRPRMKCQTAT
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB3 FLIALVWMVSILIAIPSAYFATETVLFIVKSQEKIFCGQIWPVDQQLYYKSYFLFIFGVE
:::::: ::::::::::::.::::: :::::::::::::::::::::::::::::::.:
NP_620 GLIALVWTVSILIAIPSAYFTTETVLVIVKSQEKIFCGQIWPVDQQLYYKSYFLFIFGIE
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB3 FVGPVVTMTLCYARISRELWFKAVPGFQTEQIRKRLRCRRKTVLVLMCILTAYVLCWAPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 FVGPVVTMTLCYARISRELWFKAVPGFQTEQIRKRLRCRRKTVLVLMCILTAYVLCWAPF
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB3 YGFTIVRDFFPTVFVKEKHYLTAFYVVECIAMSNSMINTVCFVTVKNNTMKYFKKMMLLH
:::::::::::::::::::::::::.:::::::::::::.:::::::.:.:::::.::::
NP_620 YGFTIVRDFFPTVFVKEKHYLTAFYIVECIAMSNSMINTLCFVTVKNDTVKYFKKIMLLH
310 320 330 340 350 360
360 370 380
pF1KB3 WRPSQRGSKSSADLDLRTNGVPTTEEVDCIRLK
:. : :.::::::::.: :.:.::::::::::
NP_620 WKASYNGGKSSADLDLKTIGMPATEEVDCIRLK
370 380 390
>>XP_005263090 (OMIM: 162642) PREDICTED: neuropeptide Y (381 aa)
initn: 350 init1: 217 opt: 530 Z-score: 519.7 bits: 104.9 E(85289): 3.3e-22
Smith-Waterman score: 530; 28.2% identity (63.0% similar) in 351 aa overlap (34-373:31-371)
10 20 30 40 50 60
pF1KB3 QNGNTSFTPNFNPPQDHASSLSFNFSYGDYDLPMDEDEDMTKTRTFFAAKIVIGIALAGI
.: : . .. . .. ...:. .: .:
XP_005 MGPIGAEADENQTVEEMKVEQYGPQTTPRGELVPDPEPELIDSTKLIEVQVVLILAYCSI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 MLVCGIGNFVFIAALTRYKKLRNLTNLLIANLAISDFLVAIICCPFEMDYYVVRQLSWEH
.:. ::: . : .. ..:..:..::..:::::..:.:: .: :: . : .. . :.
XP_005 ILLGVIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGE--WKM
70 80 90 100 110
130 140 150 160 170 180
pF1KB3 GHVLCASVNYLRTVSLYVSTNALLAIAIDRYLAIVHPLKPRMNYQTASFLIALVWMVSIL
: ::: : : . ... ::: .: .::.::. ::. :. ... . . ..:.:.: .: :
XP_005 GPVLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKISKRISFLIIGLAWGISAL
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB3 IAIPSAYFATETVLFIVKSQEKIFCGQIWPVDQQLYYKS-YFLFIFGVEFVGPVVTMTLC
.: : : : ... :. . : . : . :: ... : . : : . . .: :. ...
XP_005 LASPLAIFREYSLIEIIPDFEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIISFS
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB3 YARISRELWFKAVPGFQTEQIRKRLRCRRKTVLVLMCILTAYVLCWAPFYGFTIVRDFFP
:.:: .: .. :: ... ..: :.::. .:.:....... : :...: .. :.
XP_005 YTRIWSKLKNHVSPGAANDHYHQR---RQKTTKMLVCVVVVFAVSWLPLHAFQLAVDIDS
240 250 260 270 280 290
310 320 330 340 350
pF1KB3 TVFVKEKHYLTAFYVVECIAMSNSMINTVCFVTVKNNTMKYFKKMMLLHWRPSQRGS---
:. :.: : : . ::: ... : . . ...: ..: .: .: :: .
XP_005 QVL-DLKEYKLIFTVFHIIAMCSTFANPLLYGWMNSN----YRKAFLSAFRCEQRLDAIH
300 310 320 330 340 350
360 370 380
pF1KB3 -------KSSADLDLRTNGVPTTEEVDCIRLK
:.. .:..: :. :
XP_005 SEVSVTFKAKKNLEVRKNSGPNDSFTEATNV
360 370 380
>>NP_000901 (OMIM: 162642) neuropeptide Y receptor type (381 aa)
initn: 350 init1: 217 opt: 530 Z-score: 519.7 bits: 104.9 E(85289): 3.3e-22
Smith-Waterman score: 530; 28.2% identity (63.0% similar) in 351 aa overlap (34-373:31-371)
10 20 30 40 50 60
pF1KB3 QNGNTSFTPNFNPPQDHASSLSFNFSYGDYDLPMDEDEDMTKTRTFFAAKIVIGIALAGI
.: : . .. . .. ...:. .: .:
NP_000 MGPIGAEADENQTVEEMKVEQYGPQTTPRGELVPDPEPELIDSTKLIEVQVVLILAYCSI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 MLVCGIGNFVFIAALTRYKKLRNLTNLLIANLAISDFLVAIICCPFEMDYYVVRQLSWEH
.:. ::: . : .. ..:..:..::..:::::..:.:: .: :: . : .. . :.
NP_000 ILLGVIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGE--WKM
70 80 90 100 110
130 140 150 160 170 180
pF1KB3 GHVLCASVNYLRTVSLYVSTNALLAIAIDRYLAIVHPLKPRMNYQTASFLIALVWMVSIL
: ::: : : . ... ::: .: .::.::. ::. :. ... . . ..:.:.: .: :
NP_000 GPVLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKISKRISFLIIGLAWGISAL
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB3 IAIPSAYFATETVLFIVKSQEKIFCGQIWPVDQQLYYKS-YFLFIFGVEFVGPVVTMTLC
.: : : : ... :. . : . : . :: ... : . : : . . .: :. ...
NP_000 LASPLAIFREYSLIEIIPDFEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIISFS
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB3 YARISRELWFKAVPGFQTEQIRKRLRCRRKTVLVLMCILTAYVLCWAPFYGFTIVRDFFP
:.:: .: .. :: ... ..: :.::. .:.:....... : :...: .. :.
NP_000 YTRIWSKLKNHVSPGAANDHYHQR---RQKTTKMLVCVVVVFAVSWLPLHAFQLAVDIDS
240 250 260 270 280 290
310 320 330 340 350
pF1KB3 TVFVKEKHYLTAFYVVECIAMSNSMINTVCFVTVKNNTMKYFKKMMLLHWRPSQRGS---
:. :.: : : . ::: ... : . . ...: ..: .: .: :: .
NP_000 QVL-DLKEYKLIFTVFHIIAMCSTFANPLLYGWMNSN----YRKAFLSAFRCEQRLDAIH
300 310 320 330 340 350
360 370 380
pF1KB3 -------KSSADLDLRTNGVPTTEEVDCIRLK
:.. .:..: :. :
NP_000 SEVSVTFKAKKNLEVRKNSGPNDSFTEATNV
360 370 380
>>XP_005263091 (OMIM: 162642) PREDICTED: neuropeptide Y (381 aa)
initn: 350 init1: 217 opt: 530 Z-score: 519.7 bits: 104.9 E(85289): 3.3e-22
Smith-Waterman score: 530; 28.2% identity (63.0% similar) in 351 aa overlap (34-373:31-371)
10 20 30 40 50 60
pF1KB3 QNGNTSFTPNFNPPQDHASSLSFNFSYGDYDLPMDEDEDMTKTRTFFAAKIVIGIALAGI
.: : . .. . .. ...:. .: .:
XP_005 MGPIGAEADENQTVEEMKVEQYGPQTTPRGELVPDPEPELIDSTKLIEVQVVLILAYCSI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 MLVCGIGNFVFIAALTRYKKLRNLTNLLIANLAISDFLVAIICCPFEMDYYVVRQLSWEH
.:. ::: . : .. ..:..:..::..:::::..:.:: .: :: . : .. . :.
XP_005 ILLGVIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGE--WKM
70 80 90 100 110
130 140 150 160 170 180
pF1KB3 GHVLCASVNYLRTVSLYVSTNALLAIAIDRYLAIVHPLKPRMNYQTASFLIALVWMVSIL
: ::: : : . ... ::: .: .::.::. ::. :. ... . . ..:.:.: .: :
XP_005 GPVLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKISKRISFLIIGLAWGISAL
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB3 IAIPSAYFATETVLFIVKSQEKIFCGQIWPVDQQLYYKS-YFLFIFGVEFVGPVVTMTLC
.: : : : ... :. . : . : . :: ... : . : : . . .: :. ...
XP_005 LASPLAIFREYSLIEIIPDFEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIISFS
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB3 YARISRELWFKAVPGFQTEQIRKRLRCRRKTVLVLMCILTAYVLCWAPFYGFTIVRDFFP
:.:: .: .. :: ... ..: :.::. .:.:....... : :...: .. :.
XP_005 YTRIWSKLKNHVSPGAANDHYHQR---RQKTTKMLVCVVVVFAVSWLPLHAFQLAVDIDS
240 250 260 270 280 290
310 320 330 340 350
pF1KB3 TVFVKEKHYLTAFYVVECIAMSNSMINTVCFVTVKNNTMKYFKKMMLLHWRPSQRGS---
:. :.: : : . ::: ... : . . ...: ..: .: .: :: .
XP_005 QVL-DLKEYKLIFTVFHIIAMCSTFANPLLYGWMNSN----YRKAFLSAFRCEQRLDAIH
300 310 320 330 340 350
360 370 380
pF1KB3 -------KSSADLDLRTNGVPTTEEVDCIRLK
:.. .:..: :. :
XP_005 SEVSVTFKAKKNLEVRKNSGPNDSFTEATNV
360 370 380
>>NP_004239 (OMIM: 600895) prolactin-releasing peptide r (370 aa)
initn: 414 init1: 181 opt: 496 Z-score: 487.6 bits: 98.9 E(85289): 2e-20
Smith-Waterman score: 496; 28.7% identity (65.7% similar) in 300 aa overlap (58-352:64-353)
30 40 50 60 70 80
pF1KB3 FSYGDYDLPMDEDEDMTKTRTFFAAKIVIGIALAGIMLVCG-IGNFVFIAALTRYKKLRN
. : ....: : .:: ... ...: ..:.:
NP_004 AGNGSVAGADAPAVTPFQSLQLVHQLKGLIVLLYSVVVVVGLVGNCLLVLVIARVRRLHN
40 50 60 70 80 90
90 100 110 120 130 140
pF1KB3 LTNLLIANLAISDFLVAIICCPFEMDYYVVRQLSWEHGHVLCASVNYLRTVSLYVSTNAL
.::.::.:::.:: :. : :. . : . . .: : :: : .:. :..:::. .:
NP_004 VTNFLIGNLALSDVLMCTACVPLTLAY-AFEPRGWVFGGGLCHLVFFLQPVTVYVSVFTL
100 110 120 130 140 150
150 160 170 180 190 200
pF1KB3 LAIAIDRYLAIVHPLKPRMNYQTASFLIALVWMVSILIAIPSAYFATETVLFIVKSQEKI
.::.:::...::::. :.. . ... . .: .: ..:.:.: . .. : : ..
NP_004 TTIAVDRYVVLVHPLRRRISLRLSAYAVLAIWALSAVLALPAAVHTYHVEL---KPHDVR
160 170 180 190 200
210 220 230 240 250 260
pF1KB3 FCGQIWPVDQQLYYKSYFLFIFGVEFVGPVVTMTLCYARISRELWFKAVPGF--QTEQIR
.: ..: .:. . : .. : .. :.... : :.:.: .: ..::: :..
NP_004 LCEEFWG-SQERQRQLYAWGLLLVTYLLPLLVILLSYVRVSVKLRNRVVPGCVTQSQADW
210 220 230 240 250 260
270 280 290 300 310 320
pF1KB3 KRLRCRRKTVLVLMCILTAYVLCWAPFYGFTIVRDFFPTVFVKEKHYLTAFYVVEC--IA
: : ::.: .:. .......:: :.. :...::. : .. : .. . : .:
NP_004 DRAR-RRRTFCLLVVVVVVFAVCWLPLHVFNLLRDLDPHAI---DPYAFGLVQLLCHWLA
270 280 290 300 310 320
330 340 350 360 370 380
pF1KB3 MSNSMINTVCFVTVKNNTMKYFKKMMLLHWRPSQRGSKSSADLDLRTNGVPTTEEVDCIR
::.. : .. .... . ..:. :. :
NP_004 MSSACYNPFIYAWLHDSFREELRKL-LVAWPRKIAPHGQNMTVSVVI
330 340 350 360 370
>>NP_001049 (OMIM: 162323) substance-P receptor isoform (407 aa)
initn: 376 init1: 188 opt: 478 Z-score: 470.1 bits: 95.8 E(85289): 1.9e-19
Smith-Waterman score: 478; 23.9% identity (61.9% similar) in 318 aa overlap (32-345:8-317)
10 20 30 40 50
pF1KB3 AAQNGNTSFTPNFNPPQDHASSLSFNFSYGDYDLPMDEDEDMTKTRTFF--AAKIVIGIA
: :: . . . .. : : .::. :
NP_001 MDNVLPVDSDLSPNISTNTSEPNQFVQPAWQIVLWAA
10 20 30
60 70 80 90 100 110
pF1KB3 LAGIMLVCGI-GNFVFIAALTRYKKLRNLTNLLIANLAISDFLVAIICCPFEMDYYVVRQ
...: .. :: : . . .:..:..:: ...:::... .: . .. : : .
NP_001 AYTVIVVTSVVGNVVVMWIILAHKRMRTVTNYFLVNLAFAEASMAAFNTVVNFTYAVHNE
40 50 60 70 80 90
120 130 140 150 160 170
pF1KB3 LSWEHGHVLCASVNYLRTVSLYVSTNALLAIAIDRYLAIVHPLKPRMNYQTASFLIALVW
: .: : :.. .....: .. :.:.:::.::.:::.::.. ... .: ..:
NP_001 --WYYGLFYCKFHNFFPIAAVFASIYSMTAVAFDRYMAIIHPLQPRLSATATKVVICVIW
100 110 120 130 140 150
180 190 200 210 220 230
pF1KB3 MVSILIAIPSAYFATETVLFIVKSQEKIFCGQIWPVD-QQLYYKSYFLFIFGVEFVGPVV
....:.:.:..:..: .. .. : :: ...: : : . . . . :..
NP_001 VLALLLAFPQGYYSTTETM-----PSRVVCMIEWPEHPNKIYEKVYHICVTVLIYFLPLL
160 170 180 190 200 210
240 250 260 270 280 290
pF1KB3 TMTLCYARISRELWFKAVPGFQTEQIRKRLRCRRKTVLVLMCILTAYVLCWAPFYGFTIV
.. :. .. :: . .:: .... .... .::.: ... .. ....:: ::. : ..
NP_001 VIGYAYTVVGITLWASEIPGDSSDRYHEQVSAKRKVVKMMIVVVCTFAICWLPFHIFFLL
220 230 240 250 260 270
300 310 320 330 340 350
pF1KB3 RDFFPTVFVKEKHYLTAFYVVECIAMSNSMINTVCFVTVKNNTMKYFKKMMLLHWRPSQR
. : ...: : .. .. .:::..: : . . ... ::
NP_001 PYINPDLYLK-KFIQQVYLAIMWLAMSSTMYNPIIYCCLNDRFRLGFKHAFRCCPFISAG
280 290 300 310 320
360 370 380
pF1KB3 GSKSSADLDLRTNGVPTTEEVDCIRLK
NP_001 DYEGLEMKSTRYLQTQGSVYKVSRLETTISTVVGAHEEEPEDGPKATPSSLDLTSNCSSR
330 340 350 360 370 380
>>NP_056542 (OMIM: 162323) substance-P receptor isoform (311 aa)
initn: 376 init1: 188 opt: 475 Z-score: 468.5 bits: 95.1 E(85289): 2.3e-19
Smith-Waterman score: 475; 23.8% identity (62.7% similar) in 311 aa overlap (32-338:8-310)
10 20 30 40 50
pF1KB3 AAQNGNTSFTPNFNPPQDHASSLSFNFSYGDYDLPMDEDEDMTKTRTFF--AAKIVIGIA
: :: . . . .. : : .::. :
NP_056 MDNVLPVDSDLSPNISTNTSEPNQFVQPAWQIVLWAA
10 20 30
60 70 80 90 100 110
pF1KB3 LAGIMLVCGI-GNFVFIAALTRYKKLRNLTNLLIANLAISDFLVAIICCPFEMDYYVVRQ
...: .. :: : . . .:..:..:: ...:::... .: . .. : : .
NP_056 AYTVIVVTSVVGNVVVMWIILAHKRMRTVTNYFLVNLAFAEASMAAFNTVVNFTYAVHNE
40 50 60 70 80 90
120 130 140 150 160 170
pF1KB3 LSWEHGHVLCASVNYLRTVSLYVSTNALLAIAIDRYLAIVHPLKPRMNYQTASFLIALVW
: .: : :.. .....: .. :.:.:::.::.:::.::.. ... .: ..:
NP_056 --WYYGLFYCKFHNFFPIAAVFASIYSMTAVAFDRYMAIIHPLQPRLSATATKVVICVIW
100 110 120 130 140 150
180 190 200 210 220 230
pF1KB3 MVSILIAIPSAYFATETVLFIVKSQEKIFCGQIWPVD-QQLYYKSYFLFIFGVEFVGPVV
....:.:.:..:..: .. .. : :: ...: : : . . . . :..
NP_056 VLALLLAFPQGYYSTTETM-----PSRVVCMIEWPEHPNKIYEKVYHICVTVLIYFLPLL
160 170 180 190 200 210
240 250 260 270 280 290
pF1KB3 TMTLCYARISRELWFKAVPGFQTEQIRKRLRCRRKTVLVLMCILTAYVLCWAPFYGFTIV
.. :. .. :: . .:: .... .... .::.: ... .. ....:: ::. : ..
NP_056 VIGYAYTVVGITLWASEIPGDSSDRYHEQVSAKRKVVKMMIVVVCTFAICWLPFHIFFLL
220 230 240 250 260 270
300 310 320 330 340 350
pF1KB3 RDFFPTVFVKEKHYLTAFYVVECIAMSNSMINTVCFVTVKNNTMKYFKKMMLLHWRPSQR
. : ...: : .. .. .:::..: : . . ...
NP_056 PYINPDLYLK-KFIQQVYLAIMWLAMSSTMYNPIIYCCLNDR
280 290 300 310
360 370 380
pF1KB3 GSKSSADLDLRTNGVPTTEEVDCIRLK
384 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 21:16:36 2016 done: Thu Nov 3 21:16:37 2016
Total Scan time: 7.500 Total Display time: 0.070
Function used was FASTA [36.3.4 Apr, 2011]