FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3962, 505 aa 1>>>pF1KB3962 505 - 505 aa - 505 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 12.3906+/-0.000451; mu= -14.3967+/- 0.028 mean_var=378.6506+/-76.800, 0's: 0 Z-trim(122.0): 27 B-trim: 354 in 1/57 Lambda= 0.065911 statistics sampled from 39430 (39457) to 39430 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.772), E-opt: 0.2 (0.463), width: 16 Scan time: 12.390 The best scores are: opt bits E(85289) NP_001243019 (OMIM: 123811) cyclic AMP-dependent t ( 505) 3299 327.6 5.1e-89 NP_001871 (OMIM: 123811) cyclic AMP-dependent tran ( 505) 3299 327.6 5.1e-89 NP_001243020 (OMIM: 123811) cyclic AMP-dependent t ( 487) 3172 315.6 2.1e-85 NP_001243021 (OMIM: 123811) cyclic AMP-dependent t ( 447) 2831 283.1 1.2e-75 NP_001243022 (OMIM: 123811) cyclic AMP-dependent t ( 374) 2376 239.8 1.1e-62 XP_016874211 (OMIM: 606371) PREDICTED: cyclic AMP- ( 483) 1617 167.7 6.9e-41 XP_005268644 (OMIM: 606371) PREDICTED: cyclic AMP- ( 483) 1617 167.7 6.9e-41 NP_006847 (OMIM: 606371) cyclic AMP-dependent tran ( 483) 1617 167.7 6.9e-41 NP_001243023 (OMIM: 123811) cyclic AMP-dependent t ( 209) 1382 145.1 1.9e-34 NP_001123532 (OMIM: 606371) cyclic AMP-dependent t ( 462) 668 77.4 9.7e-14 NP_001193612 (OMIM: 606371) cyclic AMP-dependent t ( 117) 544 65.3 1.1e-10 NP_001193611 (OMIM: 606371) cyclic AMP-dependent t ( 117) 544 65.3 1.1e-10 >>NP_001243019 (OMIM: 123811) cyclic AMP-dependent trans (505 aa) initn: 3299 init1: 3299 opt: 3299 Z-score: 1719.1 bits: 327.6 E(85289): 5.1e-89 Smith-Waterman score: 3299; 100.0% identity (100.0% similar) in 505 aa overlap (1-505:1-505) 10 20 30 40 50 60 pF1KB3 MKFKLHVNSARQYKDLWNMSDDKPFLCTAPGCGQRFTNEDHLAVHKHKHEMTLKFGPARN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MKFKLHVNSARQYKDLWNMSDDKPFLCTAPGCGQRFTNEDHLAVHKHKHEMTLKFGPARN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 DSVIVADQTPTPTRFLKNCEEVGLFNELASPFENEFKKASEDDIKKMPLDLSPLATPIIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DSVIVADQTPTPTRFLKNCEEVGLFNELASPFENEFKKASEDDIKKMPLDLSPLATPIIR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 SKIEEPSVVETTHQDSPLPHPESTTSDEKEVPLAQTAQPTSAIVRPASLQVPNVLLTSSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SKIEEPSVVETTHQDSPLPHPESTTSDEKEVPLAQTAQPTSAIVRPASLQVPNVLLTSSD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 SSVIIQQAVPSPTSSTVITQAPSSNRPIVPVPGPFPLLLHLPNGQTMPVAIPASITSSNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSVIIQQAVPSPTSSTVITQAPSSNRPIVPVPGPFPLLLHLPNGQTMPVAIPASITSSNV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 HVPAAVPLVRPVTMVPSVPGIPGPSSPQPVQSEAKMRLKAALTQQHPPVTNGDTVKGHGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HVPAAVPLVRPVTMVPSVPGIPGPSSPQPVQSEAKMRLKAALTQQHPPVTNGDTVKGHGS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 GLVRTQSEESRPQSLQQPATSTTETPASPAHTTPQTQSTSGRRRRAANEDPDEKRRKFLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GLVRTQSEESRPQSLQQPATSTTETPASPAHTTPQTQSTSGRRRRAANEDPDEKRRKFLE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 RNRAAASRCRQKRKVWVQSLEKKAEDLSSLNGQLQSEVTLLRNEVAQLKQLLLAHKDCPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RNRAAASRCRQKRKVWVQSLEKKAEDLSSLNGQLQSEVTLLRNEVAQLKQLLLAHKDCPV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 TAMQKKSGYHTADKDDSSEDISVPSSPHTEAIQHSSVSTSNGVSSTSKAEAVATSVLTQM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TAMQKKSGYHTADKDDSSEDISVPSSPHTEAIQHSSVSTSNGVSSTSKAEAVATSVLTQM 430 440 450 460 470 480 490 500 pF1KB3 ADQSTEPALSQIVMAPSSQSQPSGS ::::::::::::::::::::::::: NP_001 ADQSTEPALSQIVMAPSSQSQPSGS 490 500 >>NP_001871 (OMIM: 123811) cyclic AMP-dependent transcri (505 aa) initn: 3299 init1: 3299 opt: 3299 Z-score: 1719.1 bits: 327.6 E(85289): 5.1e-89 Smith-Waterman score: 3299; 100.0% identity (100.0% similar) in 505 aa overlap (1-505:1-505) 10 20 30 40 50 60 pF1KB3 MKFKLHVNSARQYKDLWNMSDDKPFLCTAPGCGQRFTNEDHLAVHKHKHEMTLKFGPARN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MKFKLHVNSARQYKDLWNMSDDKPFLCTAPGCGQRFTNEDHLAVHKHKHEMTLKFGPARN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 DSVIVADQTPTPTRFLKNCEEVGLFNELASPFENEFKKASEDDIKKMPLDLSPLATPIIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DSVIVADQTPTPTRFLKNCEEVGLFNELASPFENEFKKASEDDIKKMPLDLSPLATPIIR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 SKIEEPSVVETTHQDSPLPHPESTTSDEKEVPLAQTAQPTSAIVRPASLQVPNVLLTSSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SKIEEPSVVETTHQDSPLPHPESTTSDEKEVPLAQTAQPTSAIVRPASLQVPNVLLTSSD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 SSVIIQQAVPSPTSSTVITQAPSSNRPIVPVPGPFPLLLHLPNGQTMPVAIPASITSSNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSVIIQQAVPSPTSSTVITQAPSSNRPIVPVPGPFPLLLHLPNGQTMPVAIPASITSSNV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 HVPAAVPLVRPVTMVPSVPGIPGPSSPQPVQSEAKMRLKAALTQQHPPVTNGDTVKGHGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HVPAAVPLVRPVTMVPSVPGIPGPSSPQPVQSEAKMRLKAALTQQHPPVTNGDTVKGHGS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 GLVRTQSEESRPQSLQQPATSTTETPASPAHTTPQTQSTSGRRRRAANEDPDEKRRKFLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GLVRTQSEESRPQSLQQPATSTTETPASPAHTTPQTQSTSGRRRRAANEDPDEKRRKFLE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB3 RNRAAASRCRQKRKVWVQSLEKKAEDLSSLNGQLQSEVTLLRNEVAQLKQLLLAHKDCPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RNRAAASRCRQKRKVWVQSLEKKAEDLSSLNGQLQSEVTLLRNEVAQLKQLLLAHKDCPV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB3 TAMQKKSGYHTADKDDSSEDISVPSSPHTEAIQHSSVSTSNGVSSTSKAEAVATSVLTQM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TAMQKKSGYHTADKDDSSEDISVPSSPHTEAIQHSSVSTSNGVSSTSKAEAVATSVLTQM 430 440 450 460 470 480 490 500 pF1KB3 ADQSTEPALSQIVMAPSSQSQPSGS ::::::::::::::::::::::::: NP_001 ADQSTEPALSQIVMAPSSQSQPSGS 490 500 >>NP_001243020 (OMIM: 123811) cyclic AMP-dependent trans (487 aa) initn: 3172 init1: 3172 opt: 3172 Z-score: 1654.1 bits: 315.6 E(85289): 2.1e-85 Smith-Waterman score: 3172; 100.0% identity (100.0% similar) in 487 aa overlap (19-505:1-487) 10 20 30 40 50 60 pF1KB3 MKFKLHVNSARQYKDLWNMSDDKPFLCTAPGCGQRFTNEDHLAVHKHKHEMTLKFGPARN :::::::::::::::::::::::::::::::::::::::::: NP_001 MSDDKPFLCTAPGCGQRFTNEDHLAVHKHKHEMTLKFGPARN 10 20 30 40 70 80 90 100 110 120 pF1KB3 DSVIVADQTPTPTRFLKNCEEVGLFNELASPFENEFKKASEDDIKKMPLDLSPLATPIIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DSVIVADQTPTPTRFLKNCEEVGLFNELASPFENEFKKASEDDIKKMPLDLSPLATPIIR 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB3 SKIEEPSVVETTHQDSPLPHPESTTSDEKEVPLAQTAQPTSAIVRPASLQVPNVLLTSSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SKIEEPSVVETTHQDSPLPHPESTTSDEKEVPLAQTAQPTSAIVRPASLQVPNVLLTSSD 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB3 SSVIIQQAVPSPTSSTVITQAPSSNRPIVPVPGPFPLLLHLPNGQTMPVAIPASITSSNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSVIIQQAVPSPTSSTVITQAPSSNRPIVPVPGPFPLLLHLPNGQTMPVAIPASITSSNV 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB3 HVPAAVPLVRPVTMVPSVPGIPGPSSPQPVQSEAKMRLKAALTQQHPPVTNGDTVKGHGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HVPAAVPLVRPVTMVPSVPGIPGPSSPQPVQSEAKMRLKAALTQQHPPVTNGDTVKGHGS 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB3 GLVRTQSEESRPQSLQQPATSTTETPASPAHTTPQTQSTSGRRRRAANEDPDEKRRKFLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GLVRTQSEESRPQSLQQPATSTTETPASPAHTTPQTQSTSGRRRRAANEDPDEKRRKFLE 290 300 310 320 330 340 370 380 390 400 410 420 pF1KB3 RNRAAASRCRQKRKVWVQSLEKKAEDLSSLNGQLQSEVTLLRNEVAQLKQLLLAHKDCPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RNRAAASRCRQKRKVWVQSLEKKAEDLSSLNGQLQSEVTLLRNEVAQLKQLLLAHKDCPV 350 360 370 380 390 400 430 440 450 460 470 480 pF1KB3 TAMQKKSGYHTADKDDSSEDISVPSSPHTEAIQHSSVSTSNGVSSTSKAEAVATSVLTQM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TAMQKKSGYHTADKDDSSEDISVPSSPHTEAIQHSSVSTSNGVSSTSKAEAVATSVLTQM 410 420 430 440 450 460 490 500 pF1KB3 ADQSTEPALSQIVMAPSSQSQPSGS ::::::::::::::::::::::::: NP_001 ADQSTEPALSQIVMAPSSQSQPSGS 470 480 >>NP_001243021 (OMIM: 123811) cyclic AMP-dependent trans (447 aa) initn: 2831 init1: 2831 opt: 2831 Z-score: 1479.4 bits: 283.1 E(85289): 1.2e-75 Smith-Waterman score: 2831; 100.0% identity (100.0% similar) in 439 aa overlap (67-505:9-447) 40 50 60 70 80 90 pF1KB3 TNEDHLAVHKHKHEMTLKFGPARNDSVIVADQTPTPTRFLKNCEEVGLFNELASPFENEF :::::::::::::::::::::::::::::: NP_001 MYCAWMWPDQTPTPTRFLKNCEEVGLFNELASPFENEF 10 20 30 100 110 120 130 140 150 pF1KB3 KKASEDDIKKMPLDLSPLATPIIRSKIEEPSVVETTHQDSPLPHPESTTSDEKEVPLAQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KKASEDDIKKMPLDLSPLATPIIRSKIEEPSVVETTHQDSPLPHPESTTSDEKEVPLAQT 40 50 60 70 80 90 160 170 180 190 200 210 pF1KB3 AQPTSAIVRPASLQVPNVLLTSSDSSVIIQQAVPSPTSSTVITQAPSSNRPIVPVPGPFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AQPTSAIVRPASLQVPNVLLTSSDSSVIIQQAVPSPTSSTVITQAPSSNRPIVPVPGPFP 100 110 120 130 140 150 220 230 240 250 260 270 pF1KB3 LLLHLPNGQTMPVAIPASITSSNVHVPAAVPLVRPVTMVPSVPGIPGPSSPQPVQSEAKM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLLHLPNGQTMPVAIPASITSSNVHVPAAVPLVRPVTMVPSVPGIPGPSSPQPVQSEAKM 160 170 180 190 200 210 280 290 300 310 320 330 pF1KB3 RLKAALTQQHPPVTNGDTVKGHGSGLVRTQSEESRPQSLQQPATSTTETPASPAHTTPQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RLKAALTQQHPPVTNGDTVKGHGSGLVRTQSEESRPQSLQQPATSTTETPASPAHTTPQT 220 230 240 250 260 270 340 350 360 370 380 390 pF1KB3 QSTSGRRRRAANEDPDEKRRKFLERNRAAASRCRQKRKVWVQSLEKKAEDLSSLNGQLQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QSTSGRRRRAANEDPDEKRRKFLERNRAAASRCRQKRKVWVQSLEKKAEDLSSLNGQLQS 280 290 300 310 320 330 400 410 420 430 440 450 pF1KB3 EVTLLRNEVAQLKQLLLAHKDCPVTAMQKKSGYHTADKDDSSEDISVPSSPHTEAIQHSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EVTLLRNEVAQLKQLLLAHKDCPVTAMQKKSGYHTADKDDSSEDISVPSSPHTEAIQHSS 340 350 360 370 380 390 460 470 480 490 500 pF1KB3 VSTSNGVSSTSKAEAVATSVLTQMADQSTEPALSQIVMAPSSQSQPSGS ::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VSTSNGVSSTSKAEAVATSVLTQMADQSTEPALSQIVMAPSSQSQPSGS 400 410 420 430 440 >>NP_001243022 (OMIM: 123811) cyclic AMP-dependent trans (374 aa) initn: 2376 init1: 2376 opt: 2376 Z-score: 1246.7 bits: 239.8 E(85289): 1.1e-62 Smith-Waterman score: 2376; 100.0% identity (100.0% similar) in 364 aa overlap (67-430:9-372) 40 50 60 70 80 90 pF1KB3 TNEDHLAVHKHKHEMTLKFGPARNDSVIVADQTPTPTRFLKNCEEVGLFNELASPFENEF :::::::::::::::::::::::::::::: NP_001 MYCAWMWPDQTPTPTRFLKNCEEVGLFNELASPFENEF 10 20 30 100 110 120 130 140 150 pF1KB3 KKASEDDIKKMPLDLSPLATPIIRSKIEEPSVVETTHQDSPLPHPESTTSDEKEVPLAQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KKASEDDIKKMPLDLSPLATPIIRSKIEEPSVVETTHQDSPLPHPESTTSDEKEVPLAQT 40 50 60 70 80 90 160 170 180 190 200 210 pF1KB3 AQPTSAIVRPASLQVPNVLLTSSDSSVIIQQAVPSPTSSTVITQAPSSNRPIVPVPGPFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AQPTSAIVRPASLQVPNVLLTSSDSSVIIQQAVPSPTSSTVITQAPSSNRPIVPVPGPFP 100 110 120 130 140 150 220 230 240 250 260 270 pF1KB3 LLLHLPNGQTMPVAIPASITSSNVHVPAAVPLVRPVTMVPSVPGIPGPSSPQPVQSEAKM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLLHLPNGQTMPVAIPASITSSNVHVPAAVPLVRPVTMVPSVPGIPGPSSPQPVQSEAKM 160 170 180 190 200 210 280 290 300 310 320 330 pF1KB3 RLKAALTQQHPPVTNGDTVKGHGSGLVRTQSEESRPQSLQQPATSTTETPASPAHTTPQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RLKAALTQQHPPVTNGDTVKGHGSGLVRTQSEESRPQSLQQPATSTTETPASPAHTTPQT 220 230 240 250 260 270 340 350 360 370 380 390 pF1KB3 QSTSGRRRRAANEDPDEKRRKFLERNRAAASRCRQKRKVWVQSLEKKAEDLSSLNGQLQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QSTSGRRRRAANEDPDEKRRKFLERNRAAASRCRQKRKVWVQSLEKKAEDLSSLNGQLQS 280 290 300 310 320 330 400 410 420 430 440 450 pF1KB3 EVTLLRNEVAQLKQLLLAHKDCPVTAMQKKSGYHTADKDDSSEDISVPSSPHTEAIQHSS :::::::::::::::::::::::::::::::::: NP_001 EVTLLRNEVAQLKQLLLAHKDCPVTAMQKKSGYHRK 340 350 360 370 460 470 480 490 500 pF1KB3 VSTSNGVSSTSKAEAVATSVLTQMADQSTEPALSQIVMAPSSQSQPSGS >>XP_016874211 (OMIM: 606371) PREDICTED: cyclic AMP-depe (483 aa) initn: 1078 init1: 555 opt: 1617 Z-score: 855.0 bits: 167.7 E(85289): 6.9e-41 Smith-Waterman score: 1680; 58.5% identity (76.4% similar) in 504 aa overlap (19-500:1-480) 10 20 30 40 50 60 pF1KB3 MKFKLHVNSARQYKDLWNMSDDKPFLCTAPGCGQRFTNEDHLAVHKHKHEMTLKFGPARN :.::.::.:.:::::::::::::::::::::::::::::::. XP_016 MGDDRPFVCNAPGCGQRFTNEDHLAVHKHKHEMTLKFGPART 10 20 30 40 70 80 90 100 110 pF1KB3 DSVIVADQTPTPTRFLKNCEEVGLFNELASPFENEFKKASEDDIKKM---PLDLSPLATP ::::.::::::::::::::::::::::::: ::.:::::...: :: :::.: .:: XP_016 DSVIIADQTPTPTRFLKNCEEVGLFNELASSFEHEFKKAADEDEKKAAAGPLDMSLPSTP 50 60 70 80 90 100 120 130 140 150 160 170 pF1KB3 IIRSKIEEPSVVETTHQDSPLPHPESTTSDEKEV---PLAQTAQPTSAIVRPASLQVPNV :. : ::: :... ::: : : :::: :. . :: .::::.:: : XP_016 DIKIKEEEPVEVDSSPPDSPASSPCSPPLKEKEVTPKPVL-ISTPTPTIVRPGSL--P-- 110 120 130 140 150 180 190 200 210 220 230 pF1KB3 LLTSSDSSVIIQQAVPSPTSSTVITQAPSSNRPIVPVPGPFPLLLHLPNGQTMPVAIPAS : . : .. ..::::: :::::: ::: . : .::..:: ::::::: .:. XP_016 LHLGYDP---LHPTLPSPTS--VITQAPPSNRQMGSPTGSLPLVMHLANGQTMPV-LPGP 160 170 180 190 200 210 240 250 260 270 280 pF1KB3 ITSSNVHVPAAVPLVRPVTMVPSVPGIPGPS-------SP--QPVQSEAKMRLKAALTQQ :..:... :.:::.:::..:::::: :: .:. :::::::::.::.: XP_016 ----PVQMPSVISLARPVSMVPNIPGIPGPPVNSSGSISPSGHPIPSEAKMRLKATLTHQ 220 230 240 250 260 290 300 310 320 330 340 pF1KB3 HPPVTNG-DTVKGHGSGLVRTQSEESRPQSLQQP-ATSTTETPASPAHTTPQTQSTSGRR ...: : : .: .: .. :.:. .:.: : : .. .:::. :: ::.::: XP_016 VSSINGGCGMVVGTASTMVTARPEQSQIL-IQHPDAPSPAQPQVSPAQPTP---STGGRR 270 280 290 300 310 320 350 360 370 380 390 400 pF1KB3 RRAANEDPDEKRRKFLERNRAAASRCRQKRKVWVQSLEKKAEDLSSLNGQLQSEVTLLRN ::...:::::.:..:::::::::::::::::.::.:::::::.:.: : ::..::::::: XP_016 RRTVDEDPDERRQRFLERNRAAASRCRQKRKLWVSSLEKKAEELTSQNIQLSNEVTLLRN 330 340 350 360 370 380 410 420 430 440 450 460 pF1KB3 EVAQLKQLLLAHKDCPVTAMQKKS-GYHTADKDDSSEDISVPSSPHTEAIQHSSVST-SN :::::::::::::::::::.:::. :: . :. ::: :.. . .:::::... :: XP_016 EVAQLKQLLLAHKDCPVTALQKKTQGYLESPKE-SSE----PTGSPAPVIQHSSATAPSN 390 400 410 420 430 470 480 490 500 pF1KB3 GVSSTSKAEAVATSVLTQMADQSTE---PALSQIVMAPSSQSQPSGS :.: : :::::::::::::.: :: : :...:.:.::: XP_016 GLSVRSAAEAVATSVLTQMASQRTELSMPIQSHVIMTPQSQSAGR 440 450 460 470 480 >>XP_005268644 (OMIM: 606371) PREDICTED: cyclic AMP-depe (483 aa) initn: 1078 init1: 555 opt: 1617 Z-score: 855.0 bits: 167.7 E(85289): 6.9e-41 Smith-Waterman score: 1680; 58.5% identity (76.4% similar) in 504 aa overlap (19-500:1-480) 10 20 30 40 50 60 pF1KB3 MKFKLHVNSARQYKDLWNMSDDKPFLCTAPGCGQRFTNEDHLAVHKHKHEMTLKFGPARN :.::.::.:.:::::::::::::::::::::::::::::::. XP_005 MGDDRPFVCNAPGCGQRFTNEDHLAVHKHKHEMTLKFGPART 10 20 30 40 70 80 90 100 110 pF1KB3 DSVIVADQTPTPTRFLKNCEEVGLFNELASPFENEFKKASEDDIKKM---PLDLSPLATP ::::.::::::::::::::::::::::::: ::.:::::...: :: :::.: .:: XP_005 DSVIIADQTPTPTRFLKNCEEVGLFNELASSFEHEFKKAADEDEKKAAAGPLDMSLPSTP 50 60 70 80 90 100 120 130 140 150 160 170 pF1KB3 IIRSKIEEPSVVETTHQDSPLPHPESTTSDEKEV---PLAQTAQPTSAIVRPASLQVPNV :. : ::: :... ::: : : :::: :. . :: .::::.:: : XP_005 DIKIKEEEPVEVDSSPPDSPASSPCSPPLKEKEVTPKPVL-ISTPTPTIVRPGSL--P-- 110 120 130 140 150 180 190 200 210 220 230 pF1KB3 LLTSSDSSVIIQQAVPSPTSSTVITQAPSSNRPIVPVPGPFPLLLHLPNGQTMPVAIPAS : . : .. ..::::: :::::: ::: . : .::..:: ::::::: .:. XP_005 LHLGYDP---LHPTLPSPTS--VITQAPPSNRQMGSPTGSLPLVMHLANGQTMPV-LPGP 160 170 180 190 200 210 240 250 260 270 280 pF1KB3 ITSSNVHVPAAVPLVRPVTMVPSVPGIPGPS-------SP--QPVQSEAKMRLKAALTQQ :..:... :.:::.:::..:::::: :: .:. :::::::::.::.: XP_005 ----PVQMPSVISLARPVSMVPNIPGIPGPPVNSSGSISPSGHPIPSEAKMRLKATLTHQ 220 230 240 250 260 290 300 310 320 330 340 pF1KB3 HPPVTNG-DTVKGHGSGLVRTQSEESRPQSLQQP-ATSTTETPASPAHTTPQTQSTSGRR ...: : : .: .: .. :.:. .:.: : : .. .:::. :: ::.::: XP_005 VSSINGGCGMVVGTASTMVTARPEQSQIL-IQHPDAPSPAQPQVSPAQPTP---STGGRR 270 280 290 300 310 320 350 360 370 380 390 400 pF1KB3 RRAANEDPDEKRRKFLERNRAAASRCRQKRKVWVQSLEKKAEDLSSLNGQLQSEVTLLRN ::...:::::.:..:::::::::::::::::.::.:::::::.:.: : ::..::::::: XP_005 RRTVDEDPDERRQRFLERNRAAASRCRQKRKLWVSSLEKKAEELTSQNIQLSNEVTLLRN 330 340 350 360 370 380 410 420 430 440 450 460 pF1KB3 EVAQLKQLLLAHKDCPVTAMQKKS-GYHTADKDDSSEDISVPSSPHTEAIQHSSVST-SN :::::::::::::::::::.:::. :: . :. ::: :.. . .:::::... :: XP_005 EVAQLKQLLLAHKDCPVTALQKKTQGYLESPKE-SSE----PTGSPAPVIQHSSATAPSN 390 400 410 420 430 470 480 490 500 pF1KB3 GVSSTSKAEAVATSVLTQMADQSTE---PALSQIVMAPSSQSQPSGS :.: : :::::::::::::.: :: : :...:.:.::: XP_005 GLSVRSAAEAVATSVLTQMASQRTELSMPIQSHVIMTPQSQSAGR 440 450 460 470 480 >>NP_006847 (OMIM: 606371) cyclic AMP-dependent transcri (483 aa) initn: 1078 init1: 555 opt: 1617 Z-score: 855.0 bits: 167.7 E(85289): 6.9e-41 Smith-Waterman score: 1680; 58.5% identity (76.4% similar) in 504 aa overlap (19-500:1-480) 10 20 30 40 50 60 pF1KB3 MKFKLHVNSARQYKDLWNMSDDKPFLCTAPGCGQRFTNEDHLAVHKHKHEMTLKFGPARN :.::.::.:.:::::::::::::::::::::::::::::::. NP_006 MGDDRPFVCNAPGCGQRFTNEDHLAVHKHKHEMTLKFGPART 10 20 30 40 70 80 90 100 110 pF1KB3 DSVIVADQTPTPTRFLKNCEEVGLFNELASPFENEFKKASEDDIKKM---PLDLSPLATP ::::.::::::::::::::::::::::::: ::.:::::...: :: :::.: .:: NP_006 DSVIIADQTPTPTRFLKNCEEVGLFNELASSFEHEFKKAADEDEKKAAAGPLDMSLPSTP 50 60 70 80 90 100 120 130 140 150 160 170 pF1KB3 IIRSKIEEPSVVETTHQDSPLPHPESTTSDEKEV---PLAQTAQPTSAIVRPASLQVPNV :. : ::: :... ::: : : :::: :. . :: .::::.:: : NP_006 DIKIKEEEPVEVDSSPPDSPASSPCSPPLKEKEVTPKPVL-ISTPTPTIVRPGSL--P-- 110 120 130 140 150 180 190 200 210 220 230 pF1KB3 LLTSSDSSVIIQQAVPSPTSSTVITQAPSSNRPIVPVPGPFPLLLHLPNGQTMPVAIPAS : . : .. ..::::: :::::: ::: . : .::..:: ::::::: .:. NP_006 LHLGYDP---LHPTLPSPTS--VITQAPPSNRQMGSPTGSLPLVMHLANGQTMPV-LPGP 160 170 180 190 200 210 240 250 260 270 280 pF1KB3 ITSSNVHVPAAVPLVRPVTMVPSVPGIPGPS-------SP--QPVQSEAKMRLKAALTQQ :..:... :.:::.:::..:::::: :: .:. :::::::::.::.: NP_006 ----PVQMPSVISLARPVSMVPNIPGIPGPPVNSSGSISPSGHPIPSEAKMRLKATLTHQ 220 230 240 250 260 290 300 310 320 330 340 pF1KB3 HPPVTNG-DTVKGHGSGLVRTQSEESRPQSLQQP-ATSTTETPASPAHTTPQTQSTSGRR ...: : : .: .: .. :.:. .:.: : : .. .:::. :: ::.::: NP_006 VSSINGGCGMVVGTASTMVTARPEQSQIL-IQHPDAPSPAQPQVSPAQPTP---STGGRR 270 280 290 300 310 320 350 360 370 380 390 400 pF1KB3 RRAANEDPDEKRRKFLERNRAAASRCRQKRKVWVQSLEKKAEDLSSLNGQLQSEVTLLRN ::...:::::.:..:::::::::::::::::.::.:::::::.:.: : ::..::::::: NP_006 RRTVDEDPDERRQRFLERNRAAASRCRQKRKLWVSSLEKKAEELTSQNIQLSNEVTLLRN 330 340 350 360 370 380 410 420 430 440 450 460 pF1KB3 EVAQLKQLLLAHKDCPVTAMQKKS-GYHTADKDDSSEDISVPSSPHTEAIQHSSVST-SN :::::::::::::::::::.:::. :: . :. ::: :.. . .:::::... :: NP_006 EVAQLKQLLLAHKDCPVTALQKKTQGYLESPKE-SSE----PTGSPAPVIQHSSATAPSN 390 400 410 420 430 470 480 490 500 pF1KB3 GVSSTSKAEAVATSVLTQMADQSTE---PALSQIVMAPSSQSQPSGS :.: : :::::::::::::.: :: : :...:.:.::: NP_006 GLSVRSAAEAVATSVLTQMASQRTELSMPIQSHVIMTPQSQSAGR 440 450 460 470 480 >>NP_001243023 (OMIM: 123811) cyclic AMP-dependent trans (209 aa) initn: 1382 init1: 1382 opt: 1382 Z-score: 739.6 bits: 145.1 E(85289): 1.9e-34 Smith-Waterman score: 1382; 100.0% identity (100.0% similar) in 209 aa overlap (1-209:1-209) 10 20 30 40 50 60 pF1KB3 MKFKLHVNSARQYKDLWNMSDDKPFLCTAPGCGQRFTNEDHLAVHKHKHEMTLKFGPARN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MKFKLHVNSARQYKDLWNMSDDKPFLCTAPGCGQRFTNEDHLAVHKHKHEMTLKFGPARN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 DSVIVADQTPTPTRFLKNCEEVGLFNELASPFENEFKKASEDDIKKMPLDLSPLATPIIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DSVIVADQTPTPTRFLKNCEEVGLFNELASPFENEFKKASEDDIKKMPLDLSPLATPIIR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 SKIEEPSVVETTHQDSPLPHPESTTSDEKEVPLAQTAQPTSAIVRPASLQVPNVLLTSSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SKIEEPSVVETTHQDSPLPHPESTTSDEKEVPLAQTAQPTSAIVRPASLQVPNVLLTSSD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 SSVIIQQAVPSPTSSTVITQAPSSNRPIVPVPGPFPLLLHLPNGQTMPVAIPASITSSNV ::::::::::::::::::::::::::::: NP_001 SSVIIQQAVPSPTSSTVITQAPSSNRPIV 190 200 >>NP_001123532 (OMIM: 606371) cyclic AMP-dependent trans (462 aa) initn: 1406 init1: 544 opt: 668 Z-score: 367.6 bits: 77.4 E(85289): 9.7e-14 Smith-Waterman score: 1611; 57.7% identity (75.4% similar) in 501 aa overlap (19-500:1-459) 10 20 30 40 50 60 pF1KB3 MKFKLHVNSARQYKDLWNMSDDKPFLCTAPGCGQRFTNEDHLAVHKHKHEMTLKFGPARN :.::.::.:.:::::::::::::::::::::::::::::::. NP_001 MGDDRPFVCNAPGCGQRFTNEDHLAVHKHKHEMTLKFGPART 10 20 30 40 70 80 90 100 110 pF1KB3 DSVIVADQTPTPTRFLKNCEEVGLFNELASPFENEFKKASEDDIKKM---PLDLSPLATP ::::.::::::::::::::::::::::::: ::.:::::...: :: :::.: .:: NP_001 DSVIIADQTPTPTRFLKNCEEVGLFNELASSFEHEFKKAADEDEKKAAAGPLDMSLPSTP 50 60 70 80 90 100 120 130 140 150 160 170 pF1KB3 IIRSKIEEPSVVETTHQDSPLPHPESTTSDEKEVPLAQTAQPTSAIVRPASLQVPNVLLT :. : ::: : :.: :.: . . :: .::::.:: : : NP_001 DIKIKEEEP-VEEVT------PKP------------VLISTPTPTIVRPGSL--P--LHL 110 120 130 180 190 200 210 220 230 pF1KB3 SSDSSVIIQQAVPSPTSSTVITQAPSSNRPIVPVPGPFPLLLHLPNGQTMPVAIPASITS . : .. ..::::: :::::: ::: . : .::..:: ::::::: .:. NP_001 GYDP---LHPTLPSPTS--VITQAPPSNRQMGSPTGSLPLVMHLANGQTMPV-LPGP--- 140 150 160 170 180 190 240 250 260 270 280 pF1KB3 SNVHVPAAVPLVRPVTMVPSVPGIPGPS-------SP--QPVQSEAKMRLKAALTQQHPP :..:... :.:::.:::..:::::: :: .:. :::::::::.::.: NP_001 -PVQMPSVISLARPVSMVPNIPGIPGPPVNSSGSISPSGHPIPSEAKMRLKATLTHQVSS 200 210 220 230 240 290 300 310 320 330 340 pF1KB3 VTNG-DTVKGHGSGLVRTQSEESRPQSLQQP-ATSTTETPASPAHTTPQTQSTSGRRRRA ...: : : .: .: .. :.:. .:.: : : .. .:::. :: ::.:::::. NP_001 INGGCGMVVGTASTMVTARPEQSQIL-IQHPDAPSPAQPQVSPAQPTP---STGGRRRRT 250 260 270 280 290 300 350 360 370 380 390 400 pF1KB3 ANEDPDEKRRKFLERNRAAASRCRQKRKVWVQSLEKKAEDLSSLNGQLQSEVTLLRNEVA ..:::::.:..:::::::::::::::::.::.:::::::.:.: : ::..:::::::::: NP_001 VDEDPDERRQRFLERNRAAASRCRQKRKLWVSSLEKKAEELTSQNIQLSNEVTLLRNEVA 310 320 330 340 350 360 410 420 430 440 450 460 pF1KB3 QLKQLLLAHKDCPVTAMQKKS-GYHTADKDDSSEDISVPSSPHTEAIQHSSVST-SNGVS ::::::::::::::::.:::. :: . :. ::: :.. . .:::::... :::.: NP_001 QLKQLLLAHKDCPVTALQKKTQGYLESPKE-SSE----PTGSPAPVIQHSSATAPSNGLS 370 380 390 400 410 420 470 480 490 500 pF1KB3 STSKAEAVATSVLTQMADQSTE---PALSQIVMAPSSQSQPSGS : :::::::::::::.: :: : :...:.:.::: NP_001 VRSAAEAVATSVLTQMASQRTELSMPIQSHVIMTPQSQSAGR 430 440 450 460 505 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 21:17:22 2016 done: Thu Nov 3 21:17:24 2016 Total Scan time: 12.390 Total Display time: 0.070 Function used was FASTA [36.3.4 Apr, 2011]