Result of FASTA (omim) for
pF1KB3963
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3963, 713 aa
1>>>pF1KB3963 713 - 713 aa - 713 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.6884+/-0.000499; mu= 11.6159+/- 0.031
mean_var=77.0803+/-16.240, 0's: 0 Z-trim(109.2): 413 B-trim: 839 in 1/53
Lambda= 0.146084
statistics sampled from 16934 (17353) to 16934 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.562), E-opt: 0.2 (0.203), width: 16
Scan time: 8.620
The best scores are: opt bits E(85289)
NP_001248 (OMIM: 601364) cadherin-13 isoform 1 pre ( 713) 4687 998.2 0
NP_001207417 (OMIM: 601364) cadherin-13 isoform 2 ( 760) 4595 978.8 0
XP_011521106 (OMIM: 601364) PREDICTED: cadherin-13 ( 612) 3895 831.3 0
NP_001207418 (OMIM: 601364) cadherin-13 isoform 3 ( 674) 3623 773.9 0
NP_001207419 (OMIM: 601364) cadherin-13 isoform 4 ( 459) 3014 645.6 1.3e-184
XP_016878337 (OMIM: 601364) PREDICTED: cadherin-13 ( 371) 2022 436.5 9e-122
XP_011524090 (OMIM: 114020) PREDICTED: cadherin-2 ( 821) 1685 365.5 4.7e-100
XP_016881003 (OMIM: 114020) PREDICTED: cadherin-2 ( 848) 1685 365.5 4.8e-100
NP_001295105 (OMIM: 114020) cadherin-2 isoform 2 [ ( 875) 1685 365.5 5e-100
NP_001783 (OMIM: 114020) cadherin-2 isoform 1 prep ( 906) 1685 365.5 5.2e-100
NP_001239268 (OMIM: 603006) cadherin-4 isoform 3 [ ( 842) 1593 346.1 3.3e-94
NP_001239267 (OMIM: 603006) cadherin-4 isoform 2 [ ( 879) 1593 346.1 3.4e-94
NP_001785 (OMIM: 603006) cadherin-4 isoform 1 prep ( 916) 1593 346.1 3.6e-94
NP_004351 (OMIM: 114480,137215,167000,176807,19209 ( 882) 1229 269.4 4.3e-71
NP_001304125 (OMIM: 114021,225280,601553) cadherin ( 774) 1210 265.4 6e-70
NP_001304124 (OMIM: 114021,225280,601553) cadherin ( 784) 1210 265.4 6.1e-70
XP_011521102 (OMIM: 114021,225280,601553) PREDICTE ( 808) 1210 265.4 6.3e-70
NP_001784 (OMIM: 114021,225280,601553) cadherin-3 ( 829) 1210 265.4 6.5e-70
NP_077741 (OMIM: 600271) desmocollin-3 isoform Dsc ( 839) 1201 263.5 2.4e-69
NP_001932 (OMIM: 600271) desmocollin-3 isoform Dsc ( 896) 1201 263.5 2.6e-69
NP_004940 (OMIM: 125645,610476) desmocollin-2 isof ( 847) 1136 249.8 3.3e-65
NP_077740 (OMIM: 125645,610476) desmocollin-2 isof ( 901) 1136 249.8 3.5e-65
XP_005258263 (OMIM: 125645,610476) PREDICTED: desm ( 758) 1102 242.6 4.2e-63
NP_001207420 (OMIM: 601364) cadherin-13 isoform 5 ( 190) 1071 236.1 1e-61
NP_001207421 (OMIM: 601364) cadherin-13 isoform 6 ( 175) 1067 235.2 1.7e-61
NP_004939 (OMIM: 125643) desmocollin-1 isoform Dsc ( 840) 1039 229.4 4.6e-59
NP_077739 (OMIM: 125643) desmocollin-1 isoform Dsc ( 894) 1039 229.4 4.9e-59
XP_016878338 (OMIM: 601364) PREDICTED: cadherin-13 ( 237) 979 216.7 8.6e-56
XP_011521790 (OMIM: 114480,137215,167000,176807,19 ( 637) 972 215.2 6.3e-55
XP_011521791 (OMIM: 114480,137215,167000,176807,19 ( 637) 972 215.2 6.3e-55
NP_817123 (OMIM: 607892,607903) desmoglein-4 isofo (1040) 968 214.4 1.8e-54
NP_001127925 (OMIM: 607892,607903) desmoglein-4 is (1059) 968 214.4 1.9e-54
NP_001934 (OMIM: 125671,610193,612877) desmoglein- (1118) 904 200.9 2.2e-50
NP_004924 (OMIM: 114019,612580) cadherin-15 prepro ( 814) 886 197.1 2.3e-49
XP_011524152 (OMIM: 169615) PREDICTED: desmoglein- ( 998) 859 191.4 1.4e-47
NP_001935 (OMIM: 169615) desmoglein-3 preproprotei ( 999) 859 191.4 1.4e-47
NP_001138135 (OMIM: 603017) cadherin-17 precursor ( 832) 831 185.5 7.2e-46
NP_004054 (OMIM: 603017) cadherin-17 precursor [Ho ( 832) 831 185.5 7.2e-46
NP_001304143 (OMIM: 605806) cadherin-7 isoform 2 p ( 630) 766 171.8 7.3e-42
NP_387450 (OMIM: 605806) cadherin-7 isoform 1 prep ( 785) 766 171.8 9e-42
NP_004352 (OMIM: 605806) cadherin-7 isoform 1 prep ( 785) 766 171.8 9e-42
XP_016881012 (OMIM: 605806) PREDICTED: cadherin-7 ( 785) 766 171.8 9e-42
NP_114097 (OMIM: 605807) cadherin-20 preproprotein ( 801) 715 161.1 1.6e-38
XP_011521103 (OMIM: 601120) PREDICTED: cadherin-5 ( 793) 694 156.6 3.4e-37
NP_001933 (OMIM: 125670,148700,615508) desmoglein- (1049) 690 155.8 8e-37
NP_067071 (OMIM: 609920) cadherin-22 precursor [Ho ( 828) 679 153.5 3.2e-36
XP_011527296 (OMIM: 609920) PREDICTED: cadherin-22 ( 828) 679 153.5 3.2e-36
XP_005255817 (OMIM: 603008) PREDICTED: cadherin-8 ( 711) 673 152.2 6.5e-36
NP_001787 (OMIM: 603008) cadherin-8 preproprotein ( 799) 673 152.2 7.3e-36
NP_001295321 (OMIM: 600023) cadherin-11 isoform 2 ( 693) 671 151.8 8.5e-36
>>NP_001248 (OMIM: 601364) cadherin-13 isoform 1 preprop (713 aa)
initn: 4687 init1: 4687 opt: 4687 Z-score: 5337.7 bits: 998.2 E(85289): 0
Smith-Waterman score: 4687; 100.0% identity (100.0% similar) in 713 aa overlap (1-713:1-713)
10 20 30 40 50 60
pF1KB3 MQPRTPLVLCVLLSQVLLLTSAEDLDCTPGFQQKVFHINQPAEFIEDQSILNLTFSDCKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MQPRTPLVLCVLLSQVLLLTSAEDLDCTPGFQQKVFHINQPAEFIEDQSILNLTFSDCKG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 NDKLRYEVSSPYFKVNSDGGLVALRNITAVGKTLFVHARTPHAEDMAELVIVGGKDIQGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NDKLRYEVSSPYFKVNSDGGLVALRNITAVGKTLFVHARTPHAEDMAELVIVGGKDIQGS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 LQDIFKFARTSPVPRQKRSIVVSPILIPENQRQPFPRDVGKVVDSDRPERSKFRLTGKGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQDIFKFARTSPVPRQKRSIVVSPILIPENQRQPFPRDVGKVVDSDRPERSKFRLTGKGV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 DQEPKGIFRINENTGSVSVTRTLDREVIAVYQLFVETTDVNGKTLEGPVPLEVIVIDQND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DQEPKGIFRINENTGSVSVTRTLDREVIAVYQLFVETTDVNGKTLEGPVPLEVIVIDQND
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 NRPIFREGPYIGHVMEGSPTGTTVMRMTAFDADDPATDNALLRYNIRQQTPDKPSPNMFY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NRPIFREGPYIGHVMEGSPTGTTVMRMTAFDADDPATDNALLRYNIRQQTPDKPSPNMFY
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 IDPEKGDIVTVVSPALLDRETLENPKYELIIEAQDMAGLDVGLTGTATATIMIDDKNDHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IDPEKGDIVTVVSPALLDRETLENPKYELIIEAQDMAGLDVGLTGTATATIMIDDKNDHS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 PKFTKKEFQATVEEGAVGVIVNLTVEDKDDPTTGAWRAAYTIINGNPGQSFEIHTNPQTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PKFTKKEFQATVEEGAVGVIVNLTVEDKDDPTTGAWRAAYTIINGNPGQSFEIHTNPQTN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 EGMLSVVKPLDYEISAFHTLLIKVENEDPLVPDVSYGPSSTATVHITVLDVNEGPVFYPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGMLSVVKPLDYEISAFHTLLIKVENEDPLVPDVSYGPSSTATVHITVLDVNEGPVFYPD
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB3 PMMVTRQEDLSVGSVLLTVNATDPDSLQHQTIRYSVYKDPAGWLNINPINGTVDTTAVLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PMMVTRQEDLSVGSVLLTVNATDPDSLQHQTIRYSVYKDPAGWLNINPINGTVDTTAVLD
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB3 RESPFVDNSVYTALFLAIDSGNPPATGTGTLLITLEDVNDNAPFIYPTVAEVCDDAKNLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RESPFVDNSVYTALFLAIDSGNPPATGTGTLLITLEDVNDNAPFIYPTVAEVCDDAKNLS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB3 VVILGASDKDLHPNTDPFKFEIHKQAVPDKVWKISKINNTHALVSLLQNLNKANYNLPIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVILGASDKDLHPNTDPFKFEIHKQAVPDKVWKISKINNTHALVSLLQNLNKANYNLPIM
610 620 630 640 650 660
670 680 690 700 710
pF1KB3 VTDSGKPPMTNITDLRVQVCSCRNSKVDCNAAGALRFSLPSVLLLSLFSLACL
:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTDSGKPPMTNITDLRVQVCSCRNSKVDCNAAGALRFSLPSVLLLSLFSLACL
670 680 690 700 710
>>NP_001207417 (OMIM: 601364) cadherin-13 isoform 2 [Hom (760 aa)
initn: 4593 init1: 4593 opt: 4595 Z-score: 5232.4 bits: 978.8 E(85289): 0
Smith-Waterman score: 4595; 98.5% identity (98.9% similar) in 713 aa overlap (1-713:50-760)
10 20 30
pF1KB3 MQPRTPLVLCVLLSQVLLLTSAEDLDCTPG
: : : . .. ::::::::::::::::
NP_001 FCAFSCPRAKQPTCTAWFPQQEHPSENGPQMPGRDPPAASTM--QVLLLTSAEDLDCTPG
20 30 40 50 60 70
40 50 60 70 80 90
pF1KB3 FQQKVFHINQPAEFIEDQSILNLTFSDCKGNDKLRYEVSSPYFKVNSDGGLVALRNITAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FQQKVFHINQPAEFIEDQSILNLTFSDCKGNDKLRYEVSSPYFKVNSDGGLVALRNITAV
80 90 100 110 120 130
100 110 120 130 140 150
pF1KB3 GKTLFVHARTPHAEDMAELVIVGGKDIQGSLQDIFKFARTSPVPRQKRSIVVSPILIPEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GKTLFVHARTPHAEDMAELVIVGGKDIQGSLQDIFKFARTSPVPRQKRSIVVSPILIPEN
140 150 160 170 180 190
160 170 180 190 200 210
pF1KB3 QRQPFPRDVGKVVDSDRPERSKFRLTGKGVDQEPKGIFRINENTGSVSVTRTLDREVIAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QRQPFPRDVGKVVDSDRPERSKFRLTGKGVDQEPKGIFRINENTGSVSVTRTLDREVIAV
200 210 220 230 240 250
220 230 240 250 260 270
pF1KB3 YQLFVETTDVNGKTLEGPVPLEVIVIDQNDNRPIFREGPYIGHVMEGSPTGTTVMRMTAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YQLFVETTDVNGKTLEGPVPLEVIVIDQNDNRPIFREGPYIGHVMEGSPTGTTVMRMTAF
260 270 280 290 300 310
280 290 300 310 320 330
pF1KB3 DADDPATDNALLRYNIRQQTPDKPSPNMFYIDPEKGDIVTVVSPALLDRETLENPKYELI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DADDPATDNALLRYNIRQQTPDKPSPNMFYIDPEKGDIVTVVSPALLDRETLENPKYELI
320 330 340 350 360 370
340 350 360 370 380 390
pF1KB3 IEAQDMAGLDVGLTGTATATIMIDDKNDHSPKFTKKEFQATVEEGAVGVIVNLTVEDKDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IEAQDMAGLDVGLTGTATATIMIDDKNDHSPKFTKKEFQATVEEGAVGVIVNLTVEDKDD
380 390 400 410 420 430
400 410 420 430 440 450
pF1KB3 PTTGAWRAAYTIINGNPGQSFEIHTNPQTNEGMLSVVKPLDYEISAFHTLLIKVENEDPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PTTGAWRAAYTIINGNPGQSFEIHTNPQTNEGMLSVVKPLDYEISAFHTLLIKVENEDPL
440 450 460 470 480 490
460 470 480 490 500 510
pF1KB3 VPDVSYGPSSTATVHITVLDVNEGPVFYPDPMMVTRQEDLSVGSVLLTVNATDPDSLQHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPDVSYGPSSTATVHITVLDVNEGPVFYPDPMMVTRQEDLSVGSVLLTVNATDPDSLQHQ
500 510 520 530 540 550
520 530 540 550 560 570
pF1KB3 TIRYSVYKDPAGWLNINPINGTVDTTAVLDRESPFVDNSVYTALFLAIDSGNPPATGTGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TIRYSVYKDPAGWLNINPINGTVDTTAVLDRESPFVDNSVYTALFLAIDSGNPPATGTGT
560 570 580 590 600 610
580 590 600 610 620 630
pF1KB3 LLITLEDVNDNAPFIYPTVAEVCDDAKNLSVVILGASDKDLHPNTDPFKFEIHKQAVPDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLITLEDVNDNAPFIYPTVAEVCDDAKNLSVVILGASDKDLHPNTDPFKFEIHKQAVPDK
620 630 640 650 660 670
640 650 660 670 680 690
pF1KB3 VWKISKINNTHALVSLLQNLNKANYNLPIMVTDSGKPPMTNITDLRVQVCSCRNSKVDCN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VWKISKINNTHALVSLLQNLNKANYNLPIMVTDSGKPPMTNITDLRVQVCSCRNSKVDCN
680 690 700 710 720 730
700 710
pF1KB3 AAGALRFSLPSVLLLSLFSLACL
:::::::::::::::::::::::
NP_001 AAGALRFSLPSVLLLSLFSLACL
740 750 760
>>XP_011521106 (OMIM: 601364) PREDICTED: cadherin-13 iso (612 aa)
initn: 3888 init1: 3888 opt: 3895 Z-score: 4436.8 bits: 831.3 E(85289): 0
Smith-Waterman score: 3895; 98.2% identity (99.2% similar) in 603 aa overlap (111-713:10-612)
90 100 110 120 130 140
pF1KB3 LVALRNITAVGKTLFVHARTPHAEDMAELVIVGGKDIQGSLQDIFKFARTSPVPRQKRSI
. : ... . .::::::::::::::::::
XP_011 MLPSHLCDDVQGLANVEQANKDIFKFARTSPVPRQKRSI
10 20 30
150 160 170 180 190 200
pF1KB3 VVSPILIPENQRQPFPRDVGKVVDSDRPERSKFRLTGKGVDQEPKGIFRINENTGSVSVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VVSPILIPENQRQPFPRDVGKVVDSDRPERSKFRLTGKGVDQEPKGIFRINENTGSVSVT
40 50 60 70 80 90
210 220 230 240 250 260
pF1KB3 RTLDREVIAVYQLFVETTDVNGKTLEGPVPLEVIVIDQNDNRPIFREGPYIGHVMEGSPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RTLDREVIAVYQLFVETTDVNGKTLEGPVPLEVIVIDQNDNRPIFREGPYIGHVMEGSPT
100 110 120 130 140 150
270 280 290 300 310 320
pF1KB3 GTTVMRMTAFDADDPATDNALLRYNIRQQTPDKPSPNMFYIDPEKGDIVTVVSPALLDRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GTTVMRMTAFDADDPATDNALLRYNIRQQTPDKPSPNMFYIDPEKGDIVTVVSPALLDRE
160 170 180 190 200 210
330 340 350 360 370 380
pF1KB3 TLENPKYELIIEAQDMAGLDVGLTGTATATIMIDDKNDHSPKFTKKEFQATVEEGAVGVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLENPKYELIIEAQDMAGLDVGLTGTATATIMIDDKNDHSPKFTKKEFQATVEEGAVGVI
220 230 240 250 260 270
390 400 410 420 430 440
pF1KB3 VNLTVEDKDDPTTGAWRAAYTIINGNPGQSFEIHTNPQTNEGMLSVVKPLDYEISAFHTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VNLTVEDKDDPTTGAWRAAYTIINGNPGQSFEIHTNPQTNEGMLSVVKPLDYEISAFHTL
280 290 300 310 320 330
450 460 470 480 490 500
pF1KB3 LIKVENEDPLVPDVSYGPSSTATVHITVLDVNEGPVFYPDPMMVTRQEDLSVGSVLLTVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LIKVENEDPLVPDVSYGPSSTATVHITVLDVNEGPVFYPDPMMVTRQEDLSVGSVLLTVN
340 350 360 370 380 390
510 520 530 540 550 560
pF1KB3 ATDPDSLQHQTIRYSVYKDPAGWLNINPINGTVDTTAVLDRESPFVDNSVYTALFLAIDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ATDPDSLQHQTIRYSVYKDPAGWLNINPINGTVDTTAVLDRESPFVDNSVYTALFLAIDS
400 410 420 430 440 450
570 580 590 600 610 620
pF1KB3 GNPPATGTGTLLITLEDVNDNAPFIYPTVAEVCDDAKNLSVVILGASDKDLHPNTDPFKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GNPPATGTGTLLITLEDVNDNAPFIYPTVAEVCDDAKNLSVVILGASDKDLHPNTDPFKF
460 470 480 490 500 510
630 640 650 660 670 680
pF1KB3 EIHKQAVPDKVWKISKINNTHALVSLLQNLNKANYNLPIMVTDSGKPPMTNITDLRVQVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EIHKQAVPDKVWKISKINNTHALVSLLQNLNKANYNLPIMVTDSGKPPMTNITDLRVQVC
520 530 540 550 560 570
690 700 710
pF1KB3 SCRNSKVDCNAAGALRFSLPSVLLLSLFSLACL
:::::::::::::::::::::::::::::::::
XP_011 SCRNSKVDCNAAGALRFSLPSVLLLSLFSLACL
580 590 600 610
>>NP_001207418 (OMIM: 601364) cadherin-13 isoform 3 prec (674 aa)
initn: 3623 init1: 3623 opt: 3623 Z-score: 4126.2 bits: 773.9 E(85289): 0
Smith-Waterman score: 4334; 94.5% identity (94.5% similar) in 713 aa overlap (1-713:1-674)
10 20 30 40 50 60
pF1KB3 MQPRTPLVLCVLLSQVLLLTSAEDLDCTPGFQQKVFHINQPAEFIEDQSILNLTFSDCKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MQPRTPLVLCVLLSQVLLLTSAEDLDCTPGFQQKVFHINQPAEFIEDQSILNLTFSDCKG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 NDKLRYEVSSPYFKVNSDGGLVALRNITAVGKTLFVHARTPHAEDMAELVIVGGKDIQGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NDKLRYEVSSPYFKVNSDGGLVALRNITAVGKTLFVHARTPHAEDMAELVIVGGKDIQGS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 LQDIFKFARTSPVPRQKRSIVVSPILIPENQRQPFPRDVGKVVDSDRPERSKFRLTGKGV
:: :::::::::::::::::::
NP_001 LQ---------------------------------------VVDSDRPERSKFRLTGKGV
130 140
190 200 210 220 230 240
pF1KB3 DQEPKGIFRINENTGSVSVTRTLDREVIAVYQLFVETTDVNGKTLEGPVPLEVIVIDQND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DQEPKGIFRINENTGSVSVTRTLDREVIAVYQLFVETTDVNGKTLEGPVPLEVIVIDQND
150 160 170 180 190 200
250 260 270 280 290 300
pF1KB3 NRPIFREGPYIGHVMEGSPTGTTVMRMTAFDADDPATDNALLRYNIRQQTPDKPSPNMFY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NRPIFREGPYIGHVMEGSPTGTTVMRMTAFDADDPATDNALLRYNIRQQTPDKPSPNMFY
210 220 230 240 250 260
310 320 330 340 350 360
pF1KB3 IDPEKGDIVTVVSPALLDRETLENPKYELIIEAQDMAGLDVGLTGTATATIMIDDKNDHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IDPEKGDIVTVVSPALLDRETLENPKYELIIEAQDMAGLDVGLTGTATATIMIDDKNDHS
270 280 290 300 310 320
370 380 390 400 410 420
pF1KB3 PKFTKKEFQATVEEGAVGVIVNLTVEDKDDPTTGAWRAAYTIINGNPGQSFEIHTNPQTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PKFTKKEFQATVEEGAVGVIVNLTVEDKDDPTTGAWRAAYTIINGNPGQSFEIHTNPQTN
330 340 350 360 370 380
430 440 450 460 470 480
pF1KB3 EGMLSVVKPLDYEISAFHTLLIKVENEDPLVPDVSYGPSSTATVHITVLDVNEGPVFYPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGMLSVVKPLDYEISAFHTLLIKVENEDPLVPDVSYGPSSTATVHITVLDVNEGPVFYPD
390 400 410 420 430 440
490 500 510 520 530 540
pF1KB3 PMMVTRQEDLSVGSVLLTVNATDPDSLQHQTIRYSVYKDPAGWLNINPINGTVDTTAVLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PMMVTRQEDLSVGSVLLTVNATDPDSLQHQTIRYSVYKDPAGWLNINPINGTVDTTAVLD
450 460 470 480 490 500
550 560 570 580 590 600
pF1KB3 RESPFVDNSVYTALFLAIDSGNPPATGTGTLLITLEDVNDNAPFIYPTVAEVCDDAKNLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RESPFVDNSVYTALFLAIDSGNPPATGTGTLLITLEDVNDNAPFIYPTVAEVCDDAKNLS
510 520 530 540 550 560
610 620 630 640 650 660
pF1KB3 VVILGASDKDLHPNTDPFKFEIHKQAVPDKVWKISKINNTHALVSLLQNLNKANYNLPIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVILGASDKDLHPNTDPFKFEIHKQAVPDKVWKISKINNTHALVSLLQNLNKANYNLPIM
570 580 590 600 610 620
670 680 690 700 710
pF1KB3 VTDSGKPPMTNITDLRVQVCSCRNSKVDCNAAGALRFSLPSVLLLSLFSLACL
:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTDSGKPPMTNITDLRVQVCSCRNSKVDCNAAGALRFSLPSVLLLSLFSLACL
630 640 650 660 670
>>NP_001207419 (OMIM: 601364) cadherin-13 isoform 4 [Hom (459 aa)
initn: 3014 init1: 3014 opt: 3014 Z-score: 3435.5 bits: 645.6 E(85289): 1.3e-184
Smith-Waterman score: 3014; 100.0% identity (100.0% similar) in 459 aa overlap (255-713:1-459)
230 240 250 260 270 280
pF1KB3 LEGPVPLEVIVIDQNDNRPIFREGPYIGHVMEGSPTGTTVMRMTAFDADDPATDNALLRY
::::::::::::::::::::::::::::::
NP_001 MEGSPTGTTVMRMTAFDADDPATDNALLRY
10 20 30
290 300 310 320 330 340
pF1KB3 NIRQQTPDKPSPNMFYIDPEKGDIVTVVSPALLDRETLENPKYELIIEAQDMAGLDVGLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NIRQQTPDKPSPNMFYIDPEKGDIVTVVSPALLDRETLENPKYELIIEAQDMAGLDVGLT
40 50 60 70 80 90
350 360 370 380 390 400
pF1KB3 GTATATIMIDDKNDHSPKFTKKEFQATVEEGAVGVIVNLTVEDKDDPTTGAWRAAYTIIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GTATATIMIDDKNDHSPKFTKKEFQATVEEGAVGVIVNLTVEDKDDPTTGAWRAAYTIIN
100 110 120 130 140 150
410 420 430 440 450 460
pF1KB3 GNPGQSFEIHTNPQTNEGMLSVVKPLDYEISAFHTLLIKVENEDPLVPDVSYGPSSTATV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GNPGQSFEIHTNPQTNEGMLSVVKPLDYEISAFHTLLIKVENEDPLVPDVSYGPSSTATV
160 170 180 190 200 210
470 480 490 500 510 520
pF1KB3 HITVLDVNEGPVFYPDPMMVTRQEDLSVGSVLLTVNATDPDSLQHQTIRYSVYKDPAGWL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HITVLDVNEGPVFYPDPMMVTRQEDLSVGSVLLTVNATDPDSLQHQTIRYSVYKDPAGWL
220 230 240 250 260 270
530 540 550 560 570 580
pF1KB3 NINPINGTVDTTAVLDRESPFVDNSVYTALFLAIDSGNPPATGTGTLLITLEDVNDNAPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NINPINGTVDTTAVLDRESPFVDNSVYTALFLAIDSGNPPATGTGTLLITLEDVNDNAPF
280 290 300 310 320 330
590 600 610 620 630 640
pF1KB3 IYPTVAEVCDDAKNLSVVILGASDKDLHPNTDPFKFEIHKQAVPDKVWKISKINNTHALV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IYPTVAEVCDDAKNLSVVILGASDKDLHPNTDPFKFEIHKQAVPDKVWKISKINNTHALV
340 350 360 370 380 390
650 660 670 680 690 700
pF1KB3 SLLQNLNKANYNLPIMVTDSGKPPMTNITDLRVQVCSCRNSKVDCNAAGALRFSLPSVLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLLQNLNKANYNLPIMVTDSGKPPMTNITDLRVQVCSCRNSKVDCNAAGALRFSLPSVLL
400 410 420 430 440 450
710
pF1KB3 LSLFSLACL
:::::::::
NP_001 LSLFSLACL
>>XP_016878337 (OMIM: 601364) PREDICTED: cadherin-13 iso (371 aa)
initn: 2020 init1: 2020 opt: 2022 Z-score: 2307.2 bits: 436.5 E(85289): 9e-122
Smith-Waterman score: 2022; 96.6% identity (97.5% similar) in 320 aa overlap (1-320:50-367)
10 20 30
pF1KB3 MQPRTPLVLCVLLSQVLLLTSAEDLDCTPG
: : : . .. ::::::::::::::::
XP_016 FCAFSCPRAKQPTCTAWFPQQEHPSENGPQMPGRDPPAASTM--QVLLLTSAEDLDCTPG
20 30 40 50 60 70
40 50 60 70 80 90
pF1KB3 FQQKVFHINQPAEFIEDQSILNLTFSDCKGNDKLRYEVSSPYFKVNSDGGLVALRNITAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FQQKVFHINQPAEFIEDQSILNLTFSDCKGNDKLRYEVSSPYFKVNSDGGLVALRNITAV
80 90 100 110 120 130
100 110 120 130 140 150
pF1KB3 GKTLFVHARTPHAEDMAELVIVGGKDIQGSLQDIFKFARTSPVPRQKRSIVVSPILIPEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GKTLFVHARTPHAEDMAELVIVGGKDIQGSLQDIFKFARTSPVPRQKRSIVVSPILIPEN
140 150 160 170 180 190
160 170 180 190 200 210
pF1KB3 QRQPFPRDVGKVVDSDRPERSKFRLTGKGVDQEPKGIFRINENTGSVSVTRTLDREVIAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QRQPFPRDVGKVVDSDRPERSKFRLTGKGVDQEPKGIFRINENTGSVSVTRTLDREVIAV
200 210 220 230 240 250
220 230 240 250 260 270
pF1KB3 YQLFVETTDVNGKTLEGPVPLEVIVIDQNDNRPIFREGPYIGHVMEGSPTGTTVMRMTAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YQLFVETTDVNGKTLEGPVPLEVIVIDQNDNRPIFREGPYIGHVMEGSPTGTTVMRMTAF
260 270 280 290 300 310
280 290 300 310 320 330
pF1KB3 DADDPATDNALLRYNIRQQTPDKPSPNMFYIDPEKGDIVTVVSPALLDRETLENPKYELI
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DADDPATDNALLRYNIRQQTPDKPSPNMFYIDPEKGDIVTVVSPALLDREGKIH
320 330 340 350 360 370
340 350 360 370 380 390
pF1KB3 IEAQDMAGLDVGLTGTATATIMIDDKNDHSPKFTKKEFQATVEEGAVGVIVNLTVEDKDD
>>XP_011524090 (OMIM: 114020) PREDICTED: cadherin-2 isof (821 aa)
initn: 1431 init1: 770 opt: 1685 Z-score: 1917.3 bits: 365.5 E(85289): 4.7e-100
Smith-Waterman score: 1685; 47.0% identity (72.6% similar) in 570 aa overlap (126-689:61-624)
100 110 120 130 140 150
pF1KB3 VHARTPHAEDMAELVIVGGKDIQGSLQDIFKFARTSP-VPRQKRSIVVSPILIPENQRQP
.:.. : . ::::. :. :: .:::.: :
XP_011 QVAVKLSLKPTLTEESVKESAEVEEIVFPRQFSKHSGHLQRQKRDWVIPPINLPENSRGP
40 50 60 70 80 90
160 170 180 190 200 210
pF1KB3 FPRDVGKV-VDSDRPERSKFRLTGKGVDQEPKGIFRINENTGSVSVTRTLDREVIAVYQL
::... .. : :. .. .:: :.:: : ::: :: .:..:::. :::: :: ..:
XP_011 FPQELVRIRSDRDKNLSLRYSVTGPGADQPPTGIFIINPISGQLSVTKPLDREQIARFHL
100 110 120 130 140 150
220 230 240 250 260 270
pF1KB3 FVETTDVNGKTLEGPVPLEVIVIDQNDNRPIFREGPYIGHVMEGSPTGTTVMRMTAFDAD
....:.::. .:.:. . . :::.::::: : . . : : ::: :: :: .::.:::
XP_011 RAHAVDINGNQVENPIDIVINVIDMNDNRPEFLHQVWNGTVPEGSKPGTYVMTVTAIDAD
160 170 180 190 200 210
280 290 300 310 320 330
pF1KB3 DPATDNALLRYNIRQQTPDKPSPNMFYIDPEKGDIVTVVSPALLDRETLENPKYELIIEA
:: . :..::: : .:.:. :::::: :. : :::.::. : :::: .. .: :::.:
XP_011 DPNALNGMLRYRIVSQAPSTPSPNMFTINNETGDIITVA--AGLDREKVQ--QYTLIIQA
220 230 240 250 260
340 350 360 370 380 390
pF1KB3 QDMAGLDV-GLTGTATATIMIDDKNDHSPKFTKKEFQATVEEGAVGVIV-NLTVEDKDDP
:: : . ::..::::.: . : ::. :.:: : . : :. : .:: :::: :::.:
XP_011 TDMEGNPTYGLSNTATAVITVTDVNDNPPEFTAMTFYGEVPENRVDIIVANLTVTDKDQP
270 280 290 300 310 320
400 410 420 430 440 450
pF1KB3 TTGAWRAAYTIINGNPGQSFEIHTNPQTNEGMLSVVKPLDYEISAFHTLLIKVENEDPLV
: :: :.: : .:.: : :.:.:..:.:...::::.:.: . . .: . .::. ::.
XP_011 HTPAWNAVYRISGGDPTGRFAIQTDPNSNDGLVTVVKPIDFETNRMFVLTVAAENQVPLA
330 340 350 360 370 380
460 470 480 490 500 510
pF1KB3 PDVSYGPSSTATVHITVLDVNEGPVFYPDPMMVTRQEDLSVGSVLLTVNATDPDSLQHQT
... :.::::: .::.::::.: : :.: .. ..: : .:..: : .: ::: ..:.
XP_011 KGIQHPPQSTATVSVTVIDVNENPYFAPNPKIIRQEEGLHAGTMLTTFTAQDPDRYMQQN
390 400 410 420 430 440
520 530 540 550 560 570
pF1KB3 IRYSVYKDPAGWLNINPINGTVDTTAVLDRESPFVDNSVYTALFLAIDSGNPPATGTGTL
:::. .:::.::.:.:.:: . : :::::::: : :..:.: ::: :.: :: .:::::
XP_011 IRYTKLSDPANWLKIDPVNGQITTIAVLDRESPNVKNNIYNATFLASDNGIPPMSGTGTL
450 460 470 480 490 500
580 590 600 610 620 630
pF1KB3 LITLEDVNDNAPFIYPTVAEVCDDAKNLSVVILGASDKDLHPNTDPFKFEIHKQAVPDKV
: : :.::::: . : ::.:. :. : : : :. ::. :: :.. . : :
XP_011 QIYLLDINDNAPQVLPQEAETCETPDPNSINIT-ALDYDIDPNAGPFAFDLPLSPVTIKR
510 520 530 540 550 560
640 650 660 670 680
pF1KB3 -WKISKINNTHALVSL-LQNLNKANYNLPIMVTDSGKPPMTNITDLRVQVCSCRNSKVDC
: :...:. : ..: .. :. . :..::..::::.:: .::. :::.::.: .:. ::
XP_011 NWTITRLNGDFAQLNLKIKFLEAGIYEVPIIITDSGNPPKSNISILRVKVCQC-DSNGDC
570 580 590 600 610 620
690 700 710
pF1KB3 NAAGALRFSLPSVLLLSLFSLACL
XP_011 TDVDRIVGAGLGTGAIIAILLCIIILLILVLMFVVWMKRRDKERQAKQLLIDPEDDVRDN
630 640 650 660 670 680
>>XP_016881003 (OMIM: 114020) PREDICTED: cadherin-2 isof (848 aa)
initn: 1431 init1: 770 opt: 1685 Z-score: 1917.1 bits: 365.5 E(85289): 4.8e-100
Smith-Waterman score: 1813; 42.9% identity (69.6% similar) in 707 aa overlap (4-689:9-709)
10 20 30 40 50
pF1KB3 MQPRTPLVLCVLLSQVLLLTSAEDLDCTPGFQQKVFHINQPAEFIEDQSILNLTF
:: : : . : :. . .:.: : :: . :. . : : .::. :
XP_016 MCRIAGALRTLLPLLAALLQASVEASGEIALCKTGFPEDVYSAVLSKDVHEGQPLLNVKF
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB3 SDCKGNDKLRYEVSSPY-FKVNSDGGLVALRN--ITAVGKTLFVHARTPHAEDMAELVI-
:.:.:. :..:: : : :::. :: . :.:. ... ....:. .... ....
XP_016 SNCNGKRKVQYESSEPADFKVDEDGMVYAVRSFPLSSEHAKFLIYAQDKETQEKWQVAVK
70 80 90 100 110 120
120 130 140 150
pF1KB3 ------VGGKDIQGS--LQDIF---KFARTSP-VPRQKRSIVVSPILIPENQRQPFPRDV
. .... : ...: .:.. : . ::::. :. :: .:::.: :::...
XP_016 LSLKPTLTEESVKESAEVEEIVFPRQFSKHSGHLQRQKRDWVIPPINLPENSRGPFPQEL
130 140 150 160 170 180
160 170 180 190 200 210
pF1KB3 GKV-VDSDRPERSKFRLTGKGVDQEPKGIFRINENTGSVSVTRTLDREVIAVYQLFVETT
.. : :. .. .:: :.:: : ::: :: .:..:::. :::: :: ..: ....
XP_016 VRIRSDRDKNLSLRYSVTGPGADQPPTGIFIINPISGQLSVTKPLDREQIARFHLRAHAV
190 200 210 220 230 240
220 230 240 250 260 270
pF1KB3 DVNGKTLEGPVPLEVIVIDQNDNRPIFREGPYIGHVMEGSPTGTTVMRMTAFDADDPATD
:.::. .:.:. . . :::.::::: : . . : : ::: :: :: .::.::::: .
XP_016 DINGNQVENPIDIVINVIDMNDNRPEFLHQVWNGTVPEGSKPGTYVMTVTAIDADDPNAL
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB3 NALLRYNIRQQTPDKPSPNMFYIDPEKGDIVTVVSPALLDRETLENPKYELIIEAQDMAG
:..::: : .:.:. :::::: :. : :::.::. : :::: .. .: :::.: :: :
XP_016 NGMLRYRIVSQAPSTPSPNMFTINNETGDIITVA--AGLDREKVQ--QYTLIIQATDMEG
310 320 330 340 350
340 350 360 370 380 390
pF1KB3 LDV-GLTGTATATIMIDDKNDHSPKFTKKEFQATVEEGAVGVIV-NLTVEDKDDPTTGAW
. ::..::::.: . : ::. :.:: : . : :. : .:: :::: :::.: : ::
XP_016 NPTYGLSNTATAVITVTDVNDNPPEFTAMTFYGEVPENRVDIIVANLTVTDKDQPHTPAW
360 370 380 390 400 410
400 410 420 430 440 450
pF1KB3 RAAYTIINGNPGQSFEIHTNPQTNEGMLSVVKPLDYEISAFHTLLIKVENEDPLVPDVSY
:.: : .:.: : :.:.:..:.:...::::.:.: . . .: . .::. ::. ...
XP_016 NAVYRISGGDPTGRFAIQTDPNSNDGLVTVVKPIDFETNRMFVLTVAAENQVPLAKGIQH
420 430 440 450 460 470
460 470 480 490 500 510
pF1KB3 GPSSTATVHITVLDVNEGPVFYPDPMMVTRQEDLSVGSVLLTVNATDPDSLQHQTIRYSV
:.::::: .::.::::.: : :.: .. ..: : .:..: : .: ::: ..:.:::.
XP_016 PPQSTATVSVTVIDVNENPYFAPNPKIIRQEEGLHAGTMLTTFTAQDPDRYMQQNIRYTK
480 490 500 510 520 530
520 530 540 550 560 570
pF1KB3 YKDPAGWLNINPINGTVDTTAVLDRESPFVDNSVYTALFLAIDSGNPPATGTGTLLITLE
.:::.::.:.:.:: . : :::::::: : :..:.: ::: :.: :: .::::: : :
XP_016 LSDPANWLKIDPVNGQITTIAVLDRESPNVKNNIYNATFLASDNGIPPMSGTGTLQIYLL
540 550 560 570 580 590
580 590 600 610 620 630
pF1KB3 DVNDNAPFIYPTVAEVCDDAKNLSVVILGASDKDLHPNTDPFKFEIHKQAVPDKV-WKIS
:.::::: . : ::.:. :. : : : :. ::. :: :.. . : : : :.
XP_016 DINDNAPQVLPQEAETCETPDPNSINIT-ALDYDIDPNAGPFAFDLPLSPVTIKRNWTIT
600 610 620 630 640 650
640 650 660 670 680 690
pF1KB3 KINNTHALVSL-LQNLNKANYNLPIMVTDSGKPPMTNITDLRVQVCSCRNSKVDCNAAGA
..:. : ..: .. :. . :..::..::::.:: .::. :::.::.: .:. ::
XP_016 RLNGDFAQLNLKIKFLEAGIYEVPIIITDSGNPPKSNISILRVKVCQC-DSNGDCTDVDR
660 670 680 690 700 710
700 710
pF1KB3 LRFSLPSVLLLSLFSLACL
XP_016 IVGAGLGTGAIIAILLCIIILLILVLMFVVWMKRRDKERQAKQLLIDPEDDVRDNILKYD
720 730 740 750 760 770
>>NP_001295105 (OMIM: 114020) cadherin-2 isoform 2 [Homo (875 aa)
initn: 1431 init1: 770 opt: 1685 Z-score: 1916.8 bits: 365.5 E(85289): 5e-100
Smith-Waterman score: 1754; 43.6% identity (71.1% similar) in 660 aa overlap (51-689:25-678)
30 40 50 60 70
pF1KB3 SAEDLDCTPGFQQKVFHINQPAEFIEDQSILNLTFSDCKGNDKLRYEVSSPY-FKVNSDG
:.. ::.:.:. :..:: : : :::. ::
NP_001 MFLLRRYVCIFTEKLKNQAELYVFLSVKFSNCNGKRKVQYESSEPADFKVDEDG
10 20 30 40 50
80 90 100 110 120
pF1KB3 GLVALRN--ITAVGKTLFVHARTPHAEDMAELVI-------VGGKDIQGS--LQDIF---
. :.:. ... ....:. .... .... . .... : ...:
NP_001 MVYAVRSFPLSSEHAKFLIYAQDKETQEKWQVAVKLSLKPTLTEESVKESAEVEEIVFPR
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB3 KFARTSP-VPRQKRSIVVSPILIPENQRQPFPRDVGKV-VDSDRPERSKFRLTGKGVDQE
.:.. : . ::::. :. :: .:::.: :::... .. : :. .. .:: :.::
NP_001 QFSKHSGHLQRQKRDWVIPPINLPENSRGPFPQELVRIRSDRDKNLSLRYSVTGPGADQP
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB3 PKGIFRINENTGSVSVTRTLDREVIAVYQLFVETTDVNGKTLEGPVPLEVIVIDQNDNRP
: ::: :: .:..:::. :::: :: ..: ....:.::. .:.:. . . :::.:::::
NP_001 PTGIFIINPISGQLSVTKPLDREQIARFHLRAHAVDINGNQVENPIDIVINVIDMNDNRP
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB3 IFREGPYIGHVMEGSPTGTTVMRMTAFDADDPATDNALLRYNIRQQTPDKPSPNMFYIDP
: . . : : ::: :: :: .::.::::: . :..::: : .:.:. :::::: :.
NP_001 EFLHQVWNGTVPEGSKPGTYVMTVTAIDADDPNALNGMLRYRIVSQAPSTPSPNMFTINN
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB3 EKGDIVTVVSPALLDRETLENPKYELIIEAQDMAGLDV-GLTGTATATIMIDDKNDHSPK
: :::.::. : :::: .. .: :::.: :: : . ::..::::.: . : ::. :.
NP_001 ETGDIITVA--AGLDREKVQ--QYTLIIQATDMEGNPTYGLSNTATAVITVTDVNDNPPE
300 310 320 330 340 350
370 380 390 400 410 420
pF1KB3 FTKKEFQATVEEGAVGVIV-NLTVEDKDDPTTGAWRAAYTIINGNPGQSFEIHTNPQTNE
:: : . : :. : .:: :::: :::.: : :: :.: : .:.: : :.:.:..:.
NP_001 FTAMTFYGEVPENRVDIIVANLTVTDKDQPHTPAWNAVYRISGGDPTGRFAIQTDPNSND
360 370 380 390 400 410
430 440 450 460 470 480
pF1KB3 GMLSVVKPLDYEISAFHTLLIKVENEDPLVPDVSYGPSSTATVHITVLDVNEGPVFYPDP
:...::::.:.: . . .: . .::. ::. ... :.::::: .::.::::.: : :.:
NP_001 GLVTVVKPIDFETNRMFVLTVAAENQVPLAKGIQHPPQSTATVSVTVIDVNENPYFAPNP
420 430 440 450 460 470
490 500 510 520 530 540
pF1KB3 MMVTRQEDLSVGSVLLTVNATDPDSLQHQTIRYSVYKDPAGWLNINPINGTVDTTAVLDR
.. ..: : .:..: : .: ::: ..:.:::. .:::.::.:.:.:: . : :::::
NP_001 KIIRQEEGLHAGTMLTTFTAQDPDRYMQQNIRYTKLSDPANWLKIDPVNGQITTIAVLDR
480 490 500 510 520 530
550 560 570 580 590 600
pF1KB3 ESPFVDNSVYTALFLAIDSGNPPATGTGTLLITLEDVNDNAPFIYPTVAEVCDDAKNLSV
::: : :..:.: ::: :.: :: .::::: : : :.::::: . : ::.:. :.
NP_001 ESPNVKNNIYNATFLASDNGIPPMSGTGTLQIYLLDINDNAPQVLPQEAETCETPDPNSI
540 550 560 570 580 590
610 620 630 640 650
pF1KB3 VILGASDKDLHPNTDPFKFEIHKQAVPDKV-WKISKINNTHALVSL-LQNLNKANYNLPI
: : : :. ::. :: :.. . : : : :...:. : ..: .. :. . :..::
NP_001 NIT-ALDYDIDPNAGPFAFDLPLSPVTIKRNWTITRLNGDFAQLNLKIKFLEAGIYEVPI
600 610 620 630 640
660 670 680 690 700 710
pF1KB3 MVTDSGKPPMTNITDLRVQVCSCRNSKVDCNAAGALRFSLPSVLLLSLFSLACL
..::::.:: .::. :::.::.: .:. ::
NP_001 IITDSGNPPKSNISILRVKVCQC-DSNGDCTDVDRIVGAGLGTGAIIAILLCIIILLILV
650 660 670 680 690 700
>>NP_001783 (OMIM: 114020) cadherin-2 isoform 1 prepropr (906 aa)
initn: 1431 init1: 770 opt: 1685 Z-score: 1916.5 bits: 365.5 E(85289): 5.2e-100
Smith-Waterman score: 1813; 42.9% identity (69.6% similar) in 707 aa overlap (4-689:9-709)
10 20 30 40 50
pF1KB3 MQPRTPLVLCVLLSQVLLLTSAEDLDCTPGFQQKVFHINQPAEFIEDQSILNLTF
:: : : . : :. . .:.: : :: . :. . : : .::. :
NP_001 MCRIAGALRTLLPLLAALLQASVEASGEIALCKTGFPEDVYSAVLSKDVHEGQPLLNVKF
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB3 SDCKGNDKLRYEVSSPY-FKVNSDGGLVALRN--ITAVGKTLFVHARTPHAEDMAELVI-
:.:.:. :..:: : : :::. :: . :.:. ... ....:. .... ....
NP_001 SNCNGKRKVQYESSEPADFKVDEDGMVYAVRSFPLSSEHAKFLIYAQDKETQEKWQVAVK
70 80 90 100 110 120
120 130 140 150
pF1KB3 ------VGGKDIQGS--LQDIF---KFARTSP-VPRQKRSIVVSPILIPENQRQPFPRDV
. .... : ...: .:.. : . ::::. :. :: .:::.: :::...
NP_001 LSLKPTLTEESVKESAEVEEIVFPRQFSKHSGHLQRQKRDWVIPPINLPENSRGPFPQEL
130 140 150 160 170 180
160 170 180 190 200 210
pF1KB3 GKV-VDSDRPERSKFRLTGKGVDQEPKGIFRINENTGSVSVTRTLDREVIAVYQLFVETT
.. : :. .. .:: :.:: : ::: :: .:..:::. :::: :: ..: ....
NP_001 VRIRSDRDKNLSLRYSVTGPGADQPPTGIFIINPISGQLSVTKPLDREQIARFHLRAHAV
190 200 210 220 230 240
220 230 240 250 260 270
pF1KB3 DVNGKTLEGPVPLEVIVIDQNDNRPIFREGPYIGHVMEGSPTGTTVMRMTAFDADDPATD
:.::. .:.:. . . :::.::::: : . . : : ::: :: :: .::.::::: .
NP_001 DINGNQVENPIDIVINVIDMNDNRPEFLHQVWNGTVPEGSKPGTYVMTVTAIDADDPNAL
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB3 NALLRYNIRQQTPDKPSPNMFYIDPEKGDIVTVVSPALLDRETLENPKYELIIEAQDMAG
:..::: : .:.:. :::::: :. : :::.::. : :::: .. .: :::.: :: :
NP_001 NGMLRYRIVSQAPSTPSPNMFTINNETGDIITVA--AGLDREKVQ--QYTLIIQATDMEG
310 320 330 340 350
340 350 360 370 380 390
pF1KB3 LDV-GLTGTATATIMIDDKNDHSPKFTKKEFQATVEEGAVGVIV-NLTVEDKDDPTTGAW
. ::..::::.: . : ::. :.:: : . : :. : .:: :::: :::.: : ::
NP_001 NPTYGLSNTATAVITVTDVNDNPPEFTAMTFYGEVPENRVDIIVANLTVTDKDQPHTPAW
360 370 380 390 400 410
400 410 420 430 440 450
pF1KB3 RAAYTIINGNPGQSFEIHTNPQTNEGMLSVVKPLDYEISAFHTLLIKVENEDPLVPDVSY
:.: : .:.: : :.:.:..:.:...::::.:.: . . .: . .::. ::. ...
NP_001 NAVYRISGGDPTGRFAIQTDPNSNDGLVTVVKPIDFETNRMFVLTVAAENQVPLAKGIQH
420 430 440 450 460 470
460 470 480 490 500 510
pF1KB3 GPSSTATVHITVLDVNEGPVFYPDPMMVTRQEDLSVGSVLLTVNATDPDSLQHQTIRYSV
:.::::: .::.::::.: : :.: .. ..: : .:..: : .: ::: ..:.:::.
NP_001 PPQSTATVSVTVIDVNENPYFAPNPKIIRQEEGLHAGTMLTTFTAQDPDRYMQQNIRYTK
480 490 500 510 520 530
520 530 540 550 560 570
pF1KB3 YKDPAGWLNINPINGTVDTTAVLDRESPFVDNSVYTALFLAIDSGNPPATGTGTLLITLE
.:::.::.:.:.:: . : :::::::: : :..:.: ::: :.: :: .::::: : :
NP_001 LSDPANWLKIDPVNGQITTIAVLDRESPNVKNNIYNATFLASDNGIPPMSGTGTLQIYLL
540 550 560 570 580 590
580 590 600 610 620 630
pF1KB3 DVNDNAPFIYPTVAEVCDDAKNLSVVILGASDKDLHPNTDPFKFEIHKQAVPDKV-WKIS
:.::::: . : ::.:. :. : : : :. ::. :: :.. . : : : :.
NP_001 DINDNAPQVLPQEAETCETPDPNSINIT-ALDYDIDPNAGPFAFDLPLSPVTIKRNWTIT
600 610 620 630 640 650
640 650 660 670 680 690
pF1KB3 KINNTHALVSL-LQNLNKANYNLPIMVTDSGKPPMTNITDLRVQVCSCRNSKVDCNAAGA
..:. : ..: .. :. . :..::..::::.:: .::. :::.::.: .:. ::
NP_001 RLNGDFAQLNLKIKFLEAGIYEVPIIITDSGNPPKSNISILRVKVCQC-DSNGDCTDVDR
660 670 680 690 700 710
700 710
pF1KB3 LRFSLPSVLLLSLFSLACL
NP_001 IVGAGLGTGAIIAILLCIIILLILVLMFVVWMKRRDKERQAKQLLIDPEDDVRDNILKYD
720 730 740 750 760 770
713 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 21:18:03 2016 done: Thu Nov 3 21:18:04 2016
Total Scan time: 8.620 Total Display time: 0.140
Function used was FASTA [36.3.4 Apr, 2011]