Result of FASTA (omim) for pF1KB3975
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB3975, 629 aa
  1>>>pF1KB3975 629 - 629 aa - 629 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 14.1705+/-0.000463; mu= -18.7652+/- 0.029
 mean_var=778.7661+/-165.966, 0's: 0 Z-trim(124.8): 598  B-trim: 0 in 0/62
 Lambda= 0.045959
 statistics sampled from 46310 (47209) to 46310 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.814), E-opt: 0.2 (0.554), width:  16
 Scan time: 14.200

The best scores are:                                      opt bits E(85289)
XP_005259455 (OMIM: 604556,615812) PREDICTED: dual ( 629) 4331 302.6 2.7e-81
NP_004705 (OMIM: 604556,615812) dual specificity t ( 629) 4331 302.6 2.7e-81
NP_006475 (OMIM: 604556,615812) dual specificity t ( 601) 2596 187.6 1.1e-46
XP_016883775 (OMIM: 600855,614104) PREDICTED: dual ( 734) 2538 183.8 1.8e-45
XP_006724041 (OMIM: 600855,614104) PREDICTED: dual ( 763) 2538 183.8 1.9e-45
XP_006724039 (OMIM: 600855,614104) PREDICTED: dual ( 763) 2538 183.8 1.9e-45
XP_006724040 (OMIM: 600855,614104) PREDICTED: dual ( 763) 2538 183.8 1.9e-45
XP_011527785 (OMIM: 600855,614104) PREDICTED: dual ( 763) 2538 183.8 1.9e-45
NP_001387 (OMIM: 600855,614104) dual specificity t ( 763) 2538 183.8 1.9e-45
XP_011527784 (OMIM: 600855,614104) PREDICTED: dual ( 770) 2538 183.9 1.9e-45
NP_567824 (OMIM: 600855,614104) dual specificity t ( 584) 2519 182.5 3.7e-45
XP_011527787 (OMIM: 600855,614104) PREDICTED: dual ( 725) 2497 181.1 1.2e-44
XP_016883773 (OMIM: 600855,614104) PREDICTED: dual ( 754) 2497 181.1 1.2e-44
XP_016883774 (OMIM: 600855,614104) PREDICTED: dual ( 754) 2497 181.1 1.2e-44
NP_569120 (OMIM: 600855,614104) dual specificity t ( 754) 2497 181.1 1.2e-44
XP_006724042 (OMIM: 600855,614104) PREDICTED: dual ( 754) 2497 181.1 1.2e-44
XP_011527786 (OMIM: 600855,614104) PREDICTED: dual ( 761) 2497 181.1 1.2e-44
NP_006474 (OMIM: 604556,615812) dual specificity t ( 589) 2489 180.5 1.5e-44
NP_569122 (OMIM: 600855,614104) dual specificity t ( 529) 2455 178.2 6.6e-44
XP_005260990 (OMIM: 600855,614104) PREDICTED: dual ( 535) 1677 126.6 2.3e-28
NP_003574 (OMIM: 603496) dual specificity tyrosine ( 528)  982 80.5 1.7e-14
XP_016875521 (OMIM: 603496) PREDICTED: dual specif ( 528)  982 80.5 1.7e-14
NP_006473 (OMIM: 603496) dual specificity tyrosine ( 601)  982 80.6 1.8e-14
XP_011508363 (OMIM: 603497) PREDICTED: dual specif ( 553)  951 78.5 7.1e-14
XP_005273372 (OMIM: 603497) PREDICTED: dual specif ( 568)  951 78.5 7.3e-14
NP_001004023 (OMIM: 603497) dual specificity tyros ( 568)  951 78.5 7.3e-14
NP_003573 (OMIM: 603497) dual specificity tyrosine ( 588)  951 78.5 7.4e-14
NP_003836 (OMIM: 609181) dual specificity tyrosine ( 520)  935 77.4 1.4e-13
XP_016856095 (OMIM: 608003) PREDICTED: homeodomain ( 605)  752 65.3 7.1e-10
NP_689909 (OMIM: 608003) homeodomain-interacting p (1075)  752 65.6   1e-09
XP_016856094 (OMIM: 608003) PREDICTED: homeodomain (1209)  752 65.7 1.1e-09
NP_938009 (OMIM: 608003) homeodomain-interacting p (1210)  752 65.7 1.1e-09
XP_005270669 (OMIM: 608003) PREDICTED: homeodomain (1210)  752 65.7 1.1e-09
XP_005270670 (OMIM: 608003) PREDICTED: homeodomain (1210)  752 65.7 1.1e-09
XP_006710506 (OMIM: 608003) PREDICTED: homeodomain (1247)  752 65.7 1.1e-09
XP_005270668 (OMIM: 608003) PREDICTED: homeodomain (1256)  752 65.7 1.1e-09
XP_005270667 (OMIM: 608003) PREDICTED: homeodomain (1280)  752 65.7 1.2e-09
XP_005270666 (OMIM: 608003) PREDICTED: homeodomain (1281)  752 65.7 1.2e-09
NP_001106710 (OMIM: 606868) homeodomain-interactin (1171)  729 64.1 3.1e-09
XP_016867558 (OMIM: 606868) PREDICTED: homeodomain (1191)  729 64.1 3.2e-09
XP_006715998 (OMIM: 606868) PREDICTED: homeodomain (1191)  729 64.1 3.2e-09
NP_073577 (OMIM: 606868) homeodomain-interacting p (1198)  729 64.1 3.2e-09
XP_011514383 (OMIM: 606868) PREDICTED: homeodomain (1206)  729 64.1 3.2e-09
XP_011514382 (OMIM: 606868) PREDICTED: homeodomain (1349)  729 64.2 3.4e-09
XP_011514381 (OMIM: 606868) PREDICTED: homeodomain (1350)  729 64.2 3.4e-09
XP_011514380 (OMIM: 606868) PREDICTED: homeodomain (1376)  729 64.2 3.5e-09
XP_011514379 (OMIM: 606868) PREDICTED: homeodomain (1377)  729 64.2 3.5e-09
XP_016872566 (OMIM: 604424) PREDICTED: homeodomain (1194)  713 63.1 6.6e-09
NP_001265092 (OMIM: 604424) homeodomain-interactin (1194)  713 63.1 6.6e-09
NP_001041665 (OMIM: 604424) homeodomain-interactin (1194)  713 63.1 6.6e-09


>>XP_005259455 (OMIM: 604556,615812) PREDICTED: dual spe  (629 aa)
 initn: 4331 init1: 4331 opt: 4331  Z-score: 1580.6  bits: 302.6 E(85289): 2.7e-81
Smith-Waterman score: 4331; 100.0% identity (100.0% similar) in 629 aa overlap (1-629:1-629)

               10        20        30        40        50        60
pF1KB3 MAVPPGHGPFSGFPGPQEHTQVLPDVRLLPRRLPLAFRDATSAPLRKLSVDLIKTYKHIN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAVPPGHGPFSGFPGPQEHTQVLPDVRLLPRRLPLAFRDATSAPLRKLSVDLIKTYKHIN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 EVYYAKKKRRAQQAPPQDSSNKKEKKVLNHGYDDDNHDYIVRSGERWLERYEIDSLIGKG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EVYYAKKKRRAQQAPPQDSSNKKEKKVLNHGYDDDNHDYIVRSGERWLERYEIDSLIGKG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 SFGQVVKAYDHQTQELVAIKIIKNKKAFLNQAQIELRLLELMNQHDTEMKYYIVHLKRHF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SFGQVVKAYDHQTQELVAIKIIKNKKAFLNQAQIELRLLELMNQHDTEMKYYIVHLKRHF
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 MFRNHLCLVFELLSYNLYDLLRNTHFRGVSLNLTRKLAQQLCTALLFLATPELSIIHCDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MFRNHLCLVFELLSYNLYDLLRNTHFRGVSLNLTRKLAQQLCTALLFLATPELSIIHCDL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 KPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGTPYDLAIDMWSLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGTPYDLAIDMWSLG
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 CILVEMHTGEPLFSGSNEVDQMNRIVEVLGIPPAAMLDQAPKARKYFERLPGGGWTLRRT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CILVEMHTGEPLFSGSNEVDQMNRIVEVLGIPPAAMLDQAPKARKYFERLPGGGWTLRRT
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 KELRKDYQGPGTRRLQEVLGVQTGGPGGRRAGEPGHSPADYLRFQDLVLRMLEYEPAARI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KELRKDYQGPGTRRLQEVLGVQTGGPGGRRAGEPGHSPADYLRFQDLVLRMLEYEPAARI
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB3 SPLGALQHGFFRRTADEATNTGPAGSSASTSPAPLDTCPSSSTASSISSSGGSSGSSSDN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SPLGALQHGFFRRTADEATNTGPAGSSASTSPAPLDTCPSSSTASSISSSGGSSGSSSDN
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB3 RTYRYSNRYCGGPGPPITDCEMNSPQVPPSQPLRPWAGGDVPHKTHQAPASASSLPGTGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RTYRYSNRYCGGPGPPITDCEMNSPQVPPSQPLRPWAGGDVPHKTHQAPASASSLPGTGA
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB3 QLPPQPRYLGRPPSPTSPPPPELMDVSLVGGPADCSPPHPAPAPQHPAASALRTRMTGGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QLPPQPRYLGRPPSPTSPPPPELMDVSLVGGPADCSPPHPAPAPQHPAASALRTRMTGGR
              550       560       570       580       590       600

              610       620         
pF1KB3 PPLPPPDDPATLGPHLGLRGVPQSTAASS
       :::::::::::::::::::::::::::::
XP_005 PPLPPPDDPATLGPHLGLRGVPQSTAASS
              610       620         

>>NP_004705 (OMIM: 604556,615812) dual specificity tyros  (629 aa)
 initn: 4331 init1: 4331 opt: 4331  Z-score: 1580.6  bits: 302.6 E(85289): 2.7e-81
Smith-Waterman score: 4331; 100.0% identity (100.0% similar) in 629 aa overlap (1-629:1-629)

               10        20        30        40        50        60
pF1KB3 MAVPPGHGPFSGFPGPQEHTQVLPDVRLLPRRLPLAFRDATSAPLRKLSVDLIKTYKHIN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MAVPPGHGPFSGFPGPQEHTQVLPDVRLLPRRLPLAFRDATSAPLRKLSVDLIKTYKHIN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 EVYYAKKKRRAQQAPPQDSSNKKEKKVLNHGYDDDNHDYIVRSGERWLERYEIDSLIGKG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 EVYYAKKKRRAQQAPPQDSSNKKEKKVLNHGYDDDNHDYIVRSGERWLERYEIDSLIGKG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 SFGQVVKAYDHQTQELVAIKIIKNKKAFLNQAQIELRLLELMNQHDTEMKYYIVHLKRHF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SFGQVVKAYDHQTQELVAIKIIKNKKAFLNQAQIELRLLELMNQHDTEMKYYIVHLKRHF
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 MFRNHLCLVFELLSYNLYDLLRNTHFRGVSLNLTRKLAQQLCTALLFLATPELSIIHCDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MFRNHLCLVFELLSYNLYDLLRNTHFRGVSLNLTRKLAQQLCTALLFLATPELSIIHCDL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 KPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGTPYDLAIDMWSLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 KPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGTPYDLAIDMWSLG
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 CILVEMHTGEPLFSGSNEVDQMNRIVEVLGIPPAAMLDQAPKARKYFERLPGGGWTLRRT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 CILVEMHTGEPLFSGSNEVDQMNRIVEVLGIPPAAMLDQAPKARKYFERLPGGGWTLRRT
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 KELRKDYQGPGTRRLQEVLGVQTGGPGGRRAGEPGHSPADYLRFQDLVLRMLEYEPAARI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 KELRKDYQGPGTRRLQEVLGVQTGGPGGRRAGEPGHSPADYLRFQDLVLRMLEYEPAARI
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB3 SPLGALQHGFFRRTADEATNTGPAGSSASTSPAPLDTCPSSSTASSISSSGGSSGSSSDN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SPLGALQHGFFRRTADEATNTGPAGSSASTSPAPLDTCPSSSTASSISSSGGSSGSSSDN
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB3 RTYRYSNRYCGGPGPPITDCEMNSPQVPPSQPLRPWAGGDVPHKTHQAPASASSLPGTGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 RTYRYSNRYCGGPGPPITDCEMNSPQVPPSQPLRPWAGGDVPHKTHQAPASASSLPGTGA
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB3 QLPPQPRYLGRPPSPTSPPPPELMDVSLVGGPADCSPPHPAPAPQHPAASALRTRMTGGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 QLPPQPRYLGRPPSPTSPPPPELMDVSLVGGPADCSPPHPAPAPQHPAASALRTRMTGGR
              550       560       570       580       590       600

              610       620         
pF1KB3 PPLPPPDDPATLGPHLGLRGVPQSTAASS
       :::::::::::::::::::::::::::::
NP_004 PPLPPPDDPATLGPHLGLRGVPQSTAASS
              610       620         

>>NP_006475 (OMIM: 604556,615812) dual specificity tyros  (601 aa)
 initn: 2624 init1: 2546 opt: 2596  Z-score: 959.1  bits: 187.6 E(85289): 1.1e-46
Smith-Waterman score: 4064; 95.5% identity (95.5% similar) in 629 aa overlap (1-629:1-601)

               10        20        30        40        50        60
pF1KB3 MAVPPGHGPFSGFPGPQEHTQVLPDVRLLPRRLPLAFRDATSAPLRKLSVDLIKTYKHIN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MAVPPGHGPFSGFPGPQEHTQVLPDVRLLPRRLPLAFRDATSAPLRKLSVDLIKTYKHIN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 EVYYAKKKRRAQQAPPQDSSNKKEKKVLNHGYDDDNHDYIVRSGERWLERYEIDSLIGKG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 EVYYAKKKRRAQQAPPQDSSNKKEKKVLNHGYDDDNHDYIVRSGERWLERYEIDSLIGKG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 SFGQVVKAYDHQTQELVAIKIIKNKKAFLNQAQIELRLLELMNQHDTEMKYYIVHLKRHF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 SFGQVVKAYDHQTQELVAIKIIKNKKAFLNQAQIELRLLELMNQHDTEMKYYIVHLKRHF
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB3 MFRNHLCLVFELLSYNLYDLLRNTHFRGVSLNLTRKLAQQLCTALLFLATPELSIIHCDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MFRNHLCLVFELLSYNLYDLLRNTHFRGVSLNLTRKLAQQLCTALLFLATPELSIIHCDL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB3 KPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGTPYDLAIDMWSLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 KPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGTPYDLAIDMWSLG
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB3 CILVEMHTGEPLFSGSNEVDQMNRIVEVLGIPPAAMLDQAPKARKYFERLPGGGWTLRRT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 CILVEMHTGEPLFSGSNEVDQMNRIVEVLGIPPAAMLDQAPKARKYFERLPGGGWTLRRT
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB3 KELRKDYQGPGTRRLQEVLGVQTGGPGGRRAGEPGHSPADYLRFQDLVLRMLEYEPAARI
       :::::::::::::::::                            :::::::::::::::
NP_006 KELRKDYQGPGTRRLQE----------------------------DLVLRMLEYEPAARI
              370                                   380       390  

              430       440       450       460       470       480
pF1KB3 SPLGALQHGFFRRTADEATNTGPAGSSASTSPAPLDTCPSSSTASSISSSGGSSGSSSDN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 SPLGALQHGFFRRTADEATNTGPAGSSASTSPAPLDTCPSSSTASSISSSGGSSGSSSDN
            400       410       420       430       440       450  

              490       500       510       520       530       540
pF1KB3 RTYRYSNRYCGGPGPPITDCEMNSPQVPPSQPLRPWAGGDVPHKTHQAPASASSLPGTGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 RTYRYSNRYCGGPGPPITDCEMNSPQVPPSQPLRPWAGGDVPHKTHQAPASASSLPGTGA
            460       470       480       490       500       510  

              550       560       570       580       590       600
pF1KB3 QLPPQPRYLGRPPSPTSPPPPELMDVSLVGGPADCSPPHPAPAPQHPAASALRTRMTGGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 QLPPQPRYLGRPPSPTSPPPPELMDVSLVGGPADCSPPHPAPAPQHPAASALRTRMTGGR
            520       530       540       550       560       570  

              610       620         
pF1KB3 PPLPPPDDPATLGPHLGLRGVPQSTAASS
       :::::::::::::::::::::::::::::
NP_006 PPLPPPDDPATLGPHLGLRGVPQSTAASS
            580       590       600 

>>XP_016883775 (OMIM: 600855,614104) PREDICTED: dual spe  (734 aa)
 initn: 2472 init1: 2446 opt: 2538  Z-score: 937.3  bits: 183.8 E(85289): 1.8e-45
Smith-Waterman score: 2538; 71.3% identity (87.0% similar) in 537 aa overlap (21-549:40-569)

                         10        20        30        40        50
pF1KB3           MAVPPGHGPFSGFPGPQEHTQVLPDVRLLPRRLPLAFRDATSAPLRKLSV
                                     ::.::. .: ::.: .::: ..::::::::
XP_016 QYSDRRQPNISDQQVSALSYSDQIQQPLTNQVMPDIVMLQRRMPQTFRDPATAPLRKLSV
      10        20        30        40        50        60         

               60        70        80        90       100       110
pF1KB3 DLIKTYKHINEVYYAKKKRRAQQAPPQDSSNKKEKKVLNHGYDDDNHDYIVRSGERWLER
       :::::::::::::::::::: ::.  .:::.:::.:: : ::::::.::::..::.:..:
XP_016 DLIKTYKHINEVYYAKKKRRHQQGQGDDSSHKKERKVYNDGYDDDNYDYIVKNGEKWMDR
      70        80        90       100       110       120         

              120       130       140       150       160       170
pF1KB3 YEIDSLIGKGSFGQVVKAYDHQTQELVAIKIIKNKKAFLNQAQIELRLLELMNQHDTEMK
       ::::::::::::::::::::.  :: :::::::::::::::::::.:::::::.::::::
XP_016 YEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMK
     130       140       150       160       170       180         

              180       190       200       210       220       230
pF1KB3 YYIVHLKRHFMFRNHLCLVFELLSYNLYDLLRNTHFRGVSLNLTRKLAQQLCTALLFLAT
       :::::::::::::::::::::.::::::::::::.:::::::::::.:::.:::::::::
XP_016 YYIVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLAT
     190       200       210       220       230       240         

              240       250       260       270       280       290
pF1KB3 PELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGTPY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::
XP_016 PELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPY
     250       260       270       280       290       300         

              300       310       320       330       340       350
pF1KB3 DLAIDMWSLGCILVEMHTGEPLFSGSNEVDQMNRIVEVLGIPPAAMLDQAPKARKYFERL
       :::::::::::::::::::::::::.:::::::.:::::::::: .:::::::::.::.:
XP_016 DLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIPPAHILDQAPKARKFFEKL
     310       320       330       340       350       360         

              360       370       380       390       400       410
pF1KB3 PGGGWTLRRTKELRKDYQGPGTRRLQEVLGVQTGGPGGRRAGEPGHSPADYLRFQDLVLR
       : : :.:..::. ...:. ::::.:...:::.::::::::::: ::. ::::.:.::.::
XP_016 PDGTWNLKKTKDGKREYKPPGTRKLHNILGVETGGPGGRRAGESGHTVADYLKFKDLILR
     370       380       390       400       410       420         

              420       430       440       450       460       470
pF1KB3 MLEYEPAARISPLGALQHGFFRRTADEATNTGPAGSSASTSPAPLDTCPSSSTASSISSS
       ::.:.: .::.:  ::::.::..::::.:::   ..:.:::::  ..  :..:.:. :::
XP_016 MLDYDPKTRIQPYYALQHSFFKKTADEGTNT---SNSVSTSPAMEQSQSSGTTSSTSSSS
     430       440       450       460          470       480      

              480          490          500       510         520  
pF1KB3 GGSSGSSSDNRTYR---YSNRYCGG---PGPPITDCEMNSPQVPPSQPLRP--WAGGDVP
       :::::.:...:.     ...:. ::    .    ::: .::::  . :  :  :.: ..:
XP_016 GGSSGTSNSGRARSDPTHQHRHSGGHFTAAVQAMDCETHSPQVRQQFPA-PLGWSGTEAP
        490       500       510       520       530        540     

            530       540       550       560       570       580  
pF1KB3 HKTHQAPASASSLPGTGAQLPPQPRYLGRPPSPTSPPPPELMDVSLVGGPADCSPPHPAP
           :. . .  .  :  .. ::   :                                 
XP_016 T---QVTVETHPVQETTFHVAPQQNALHHHHGNSSHHHHHHHHHHHHHGQQALGNRTRPR
            550       560       570       580       590       600  

>>XP_006724041 (OMIM: 600855,614104) PREDICTED: dual spe  (763 aa)
 initn: 2472 init1: 2446 opt: 2538  Z-score: 937.1  bits: 183.8 E(85289): 1.9e-45
Smith-Waterman score: 2538; 71.3% identity (87.0% similar) in 537 aa overlap (21-549:69-598)

                         10        20        30        40        50
pF1KB3           MAVPPGHGPFSGFPGPQEHTQVLPDVRLLPRRLPLAFRDATSAPLRKLSV
                                     ::.::. .: ::.: .::: ..::::::::
XP_006 QYSDRRQPNISDQQVSALSYSDQIQQPLTNQVMPDIVMLQRRMPQTFRDPATAPLRKLSV
       40        50        60        70        80        90        

               60        70        80        90       100       110
pF1KB3 DLIKTYKHINEVYYAKKKRRAQQAPPQDSSNKKEKKVLNHGYDDDNHDYIVRSGERWLER
       :::::::::::::::::::: ::.  .:::.:::.:: : ::::::.::::..::.:..:
XP_006 DLIKTYKHINEVYYAKKKRRHQQGQGDDSSHKKERKVYNDGYDDDNYDYIVKNGEKWMDR
      100       110       120       130       140       150        

              120       130       140       150       160       170
pF1KB3 YEIDSLIGKGSFGQVVKAYDHQTQELVAIKIIKNKKAFLNQAQIELRLLELMNQHDTEMK
       ::::::::::::::::::::.  :: :::::::::::::::::::.:::::::.::::::
XP_006 YEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMK
      160       170       180       190       200       210        

              180       190       200       210       220       230
pF1KB3 YYIVHLKRHFMFRNHLCLVFELLSYNLYDLLRNTHFRGVSLNLTRKLAQQLCTALLFLAT
       :::::::::::::::::::::.::::::::::::.:::::::::::.:::.:::::::::
XP_006 YYIVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLAT
      220       230       240       250       260       270        

              240       250       260       270       280       290
pF1KB3 PELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGTPY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::
XP_006 PELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPY
      280       290       300       310       320       330        

              300       310       320       330       340       350
pF1KB3 DLAIDMWSLGCILVEMHTGEPLFSGSNEVDQMNRIVEVLGIPPAAMLDQAPKARKYFERL
       :::::::::::::::::::::::::.:::::::.:::::::::: .:::::::::.::.:
XP_006 DLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIPPAHILDQAPKARKFFEKL
      340       350       360       370       380       390        

              360       370       380       390       400       410
pF1KB3 PGGGWTLRRTKELRKDYQGPGTRRLQEVLGVQTGGPGGRRAGEPGHSPADYLRFQDLVLR
       : : :.:..::. ...:. ::::.:...:::.::::::::::: ::. ::::.:.::.::
XP_006 PDGTWNLKKTKDGKREYKPPGTRKLHNILGVETGGPGGRRAGESGHTVADYLKFKDLILR
      400       410       420       430       440       450        

              420       430       440       450       460       470
pF1KB3 MLEYEPAARISPLGALQHGFFRRTADEATNTGPAGSSASTSPAPLDTCPSSSTASSISSS
       ::.:.: .::.:  ::::.::..::::.:::   ..:.:::::  ..  :..:.:. :::
XP_006 MLDYDPKTRIQPYYALQHSFFKKTADEGTNT---SNSVSTSPAMEQSQSSGTTSSTSSSS
      460       470       480          490       500       510     

              480          490          500       510         520  
pF1KB3 GGSSGSSSDNRTYR---YSNRYCGG---PGPPITDCEMNSPQVPPSQPLRP--WAGGDVP
       :::::.:...:.     ...:. ::    .    ::: .::::  . :  :  :.: ..:
XP_006 GGSSGTSNSGRARSDPTHQHRHSGGHFTAAVQAMDCETHSPQVRQQFPA-PLGWSGTEAP
         520       530       540       550       560        570    

            530       540       550       560       570       580  
pF1KB3 HKTHQAPASASSLPGTGAQLPPQPRYLGRPPSPTSPPPPELMDVSLVGGPADCSPPHPAP
           :. . .  .  :  .. ::   :                                 
XP_006 T---QVTVETHPVQETTFHVAPQQNALHHHHGNSSHHHHHHHHHHHHHGQQALGNRTRPR
             580       590       600       610       620       630 

>>XP_006724039 (OMIM: 600855,614104) PREDICTED: dual spe  (763 aa)
 initn: 2472 init1: 2446 opt: 2538  Z-score: 937.1  bits: 183.8 E(85289): 1.9e-45
Smith-Waterman score: 2538; 71.3% identity (87.0% similar) in 537 aa overlap (21-549:69-598)

                         10        20        30        40        50
pF1KB3           MAVPPGHGPFSGFPGPQEHTQVLPDVRLLPRRLPLAFRDATSAPLRKLSV
                                     ::.::. .: ::.: .::: ..::::::::
XP_006 QYSDRRQPNISDQQVSALSYSDQIQQPLTNQVMPDIVMLQRRMPQTFRDPATAPLRKLSV
       40        50        60        70        80        90        

               60        70        80        90       100       110
pF1KB3 DLIKTYKHINEVYYAKKKRRAQQAPPQDSSNKKEKKVLNHGYDDDNHDYIVRSGERWLER
       :::::::::::::::::::: ::.  .:::.:::.:: : ::::::.::::..::.:..:
XP_006 DLIKTYKHINEVYYAKKKRRHQQGQGDDSSHKKERKVYNDGYDDDNYDYIVKNGEKWMDR
      100       110       120       130       140       150        

              120       130       140       150       160       170
pF1KB3 YEIDSLIGKGSFGQVVKAYDHQTQELVAIKIIKNKKAFLNQAQIELRLLELMNQHDTEMK
       ::::::::::::::::::::.  :: :::::::::::::::::::.:::::::.::::::
XP_006 YEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMK
      160       170       180       190       200       210        

              180       190       200       210       220       230
pF1KB3 YYIVHLKRHFMFRNHLCLVFELLSYNLYDLLRNTHFRGVSLNLTRKLAQQLCTALLFLAT
       :::::::::::::::::::::.::::::::::::.:::::::::::.:::.:::::::::
XP_006 YYIVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLAT
      220       230       240       250       260       270        

              240       250       260       270       280       290
pF1KB3 PELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGTPY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::
XP_006 PELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPY
      280       290       300       310       320       330        

              300       310       320       330       340       350
pF1KB3 DLAIDMWSLGCILVEMHTGEPLFSGSNEVDQMNRIVEVLGIPPAAMLDQAPKARKYFERL
       :::::::::::::::::::::::::.:::::::.:::::::::: .:::::::::.::.:
XP_006 DLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIPPAHILDQAPKARKFFEKL
      340       350       360       370       380       390        

              360       370       380       390       400       410
pF1KB3 PGGGWTLRRTKELRKDYQGPGTRRLQEVLGVQTGGPGGRRAGEPGHSPADYLRFQDLVLR
       : : :.:..::. ...:. ::::.:...:::.::::::::::: ::. ::::.:.::.::
XP_006 PDGTWNLKKTKDGKREYKPPGTRKLHNILGVETGGPGGRRAGESGHTVADYLKFKDLILR
      400       410       420       430       440       450        

              420       430       440       450       460       470
pF1KB3 MLEYEPAARISPLGALQHGFFRRTADEATNTGPAGSSASTSPAPLDTCPSSSTASSISSS
       ::.:.: .::.:  ::::.::..::::.:::   ..:.:::::  ..  :..:.:. :::
XP_006 MLDYDPKTRIQPYYALQHSFFKKTADEGTNT---SNSVSTSPAMEQSQSSGTTSSTSSSS
      460       470       480          490       500       510     

              480          490          500       510         520  
pF1KB3 GGSSGSSSDNRTYR---YSNRYCGG---PGPPITDCEMNSPQVPPSQPLRP--WAGGDVP
       :::::.:...:.     ...:. ::    .    ::: .::::  . :  :  :.: ..:
XP_006 GGSSGTSNSGRARSDPTHQHRHSGGHFTAAVQAMDCETHSPQVRQQFPA-PLGWSGTEAP
         520       530       540       550       560        570    

            530       540       550       560       570       580  
pF1KB3 HKTHQAPASASSLPGTGAQLPPQPRYLGRPPSPTSPPPPELMDVSLVGGPADCSPPHPAP
           :. . .  .  :  .. ::   :                                 
XP_006 T---QVTVETHPVQETTFHVAPQQNALHHHHGNSSHHHHHHHHHHHHHGQQALGNRTRPR
             580       590       600       610       620       630 

>>XP_006724040 (OMIM: 600855,614104) PREDICTED: dual spe  (763 aa)
 initn: 2472 init1: 2446 opt: 2538  Z-score: 937.1  bits: 183.8 E(85289): 1.9e-45
Smith-Waterman score: 2538; 71.3% identity (87.0% similar) in 537 aa overlap (21-549:69-598)

                         10        20        30        40        50
pF1KB3           MAVPPGHGPFSGFPGPQEHTQVLPDVRLLPRRLPLAFRDATSAPLRKLSV
                                     ::.::. .: ::.: .::: ..::::::::
XP_006 QYSDRRQPNISDQQVSALSYSDQIQQPLTNQVMPDIVMLQRRMPQTFRDPATAPLRKLSV
       40        50        60        70        80        90        

               60        70        80        90       100       110
pF1KB3 DLIKTYKHINEVYYAKKKRRAQQAPPQDSSNKKEKKVLNHGYDDDNHDYIVRSGERWLER
       :::::::::::::::::::: ::.  .:::.:::.:: : ::::::.::::..::.:..:
XP_006 DLIKTYKHINEVYYAKKKRRHQQGQGDDSSHKKERKVYNDGYDDDNYDYIVKNGEKWMDR
      100       110       120       130       140       150        

              120       130       140       150       160       170
pF1KB3 YEIDSLIGKGSFGQVVKAYDHQTQELVAIKIIKNKKAFLNQAQIELRLLELMNQHDTEMK
       ::::::::::::::::::::.  :: :::::::::::::::::::.:::::::.::::::
XP_006 YEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMK
      160       170       180       190       200       210        

              180       190       200       210       220       230
pF1KB3 YYIVHLKRHFMFRNHLCLVFELLSYNLYDLLRNTHFRGVSLNLTRKLAQQLCTALLFLAT
       :::::::::::::::::::::.::::::::::::.:::::::::::.:::.:::::::::
XP_006 YYIVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLAT
      220       230       240       250       260       270        

              240       250       260       270       280       290
pF1KB3 PELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGTPY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::
XP_006 PELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPY
      280       290       300       310       320       330        

              300       310       320       330       340       350
pF1KB3 DLAIDMWSLGCILVEMHTGEPLFSGSNEVDQMNRIVEVLGIPPAAMLDQAPKARKYFERL
       :::::::::::::::::::::::::.:::::::.:::::::::: .:::::::::.::.:
XP_006 DLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIPPAHILDQAPKARKFFEKL
      340       350       360       370       380       390        

              360       370       380       390       400       410
pF1KB3 PGGGWTLRRTKELRKDYQGPGTRRLQEVLGVQTGGPGGRRAGEPGHSPADYLRFQDLVLR
       : : :.:..::. ...:. ::::.:...:::.::::::::::: ::. ::::.:.::.::
XP_006 PDGTWNLKKTKDGKREYKPPGTRKLHNILGVETGGPGGRRAGESGHTVADYLKFKDLILR
      400       410       420       430       440       450        

              420       430       440       450       460       470
pF1KB3 MLEYEPAARISPLGALQHGFFRRTADEATNTGPAGSSASTSPAPLDTCPSSSTASSISSS
       ::.:.: .::.:  ::::.::..::::.:::   ..:.:::::  ..  :..:.:. :::
XP_006 MLDYDPKTRIQPYYALQHSFFKKTADEGTNT---SNSVSTSPAMEQSQSSGTTSSTSSSS
      460       470       480          490       500       510     

              480          490          500       510         520  
pF1KB3 GGSSGSSSDNRTYR---YSNRYCGG---PGPPITDCEMNSPQVPPSQPLRP--WAGGDVP
       :::::.:...:.     ...:. ::    .    ::: .::::  . :  :  :.: ..:
XP_006 GGSSGTSNSGRARSDPTHQHRHSGGHFTAAVQAMDCETHSPQVRQQFPA-PLGWSGTEAP
         520       530       540       550       560        570    

            530       540       550       560       570       580  
pF1KB3 HKTHQAPASASSLPGTGAQLPPQPRYLGRPPSPTSPPPPELMDVSLVGGPADCSPPHPAP
           :. . .  .  :  .. ::   :                                 
XP_006 T---QVTVETHPVQETTFHVAPQQNALHHHHGNSSHHHHHHHHHHHHHGQQALGNRTRPR
             580       590       600       610       620       630 

>>XP_011527785 (OMIM: 600855,614104) PREDICTED: dual spe  (763 aa)
 initn: 2472 init1: 2446 opt: 2538  Z-score: 937.1  bits: 183.8 E(85289): 1.9e-45
Smith-Waterman score: 2538; 71.3% identity (87.0% similar) in 537 aa overlap (21-549:69-598)

                         10        20        30        40        50
pF1KB3           MAVPPGHGPFSGFPGPQEHTQVLPDVRLLPRRLPLAFRDATSAPLRKLSV
                                     ::.::. .: ::.: .::: ..::::::::
XP_011 QYSDRRQPNISDQQVSALSYSDQIQQPLTNQVMPDIVMLQRRMPQTFRDPATAPLRKLSV
       40        50        60        70        80        90        

               60        70        80        90       100       110
pF1KB3 DLIKTYKHINEVYYAKKKRRAQQAPPQDSSNKKEKKVLNHGYDDDNHDYIVRSGERWLER
       :::::::::::::::::::: ::.  .:::.:::.:: : ::::::.::::..::.:..:
XP_011 DLIKTYKHINEVYYAKKKRRHQQGQGDDSSHKKERKVYNDGYDDDNYDYIVKNGEKWMDR
      100       110       120       130       140       150        

              120       130       140       150       160       170
pF1KB3 YEIDSLIGKGSFGQVVKAYDHQTQELVAIKIIKNKKAFLNQAQIELRLLELMNQHDTEMK
       ::::::::::::::::::::.  :: :::::::::::::::::::.:::::::.::::::
XP_011 YEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMK
      160       170       180       190       200       210        

              180       190       200       210       220       230
pF1KB3 YYIVHLKRHFMFRNHLCLVFELLSYNLYDLLRNTHFRGVSLNLTRKLAQQLCTALLFLAT
       :::::::::::::::::::::.::::::::::::.:::::::::::.:::.:::::::::
XP_011 YYIVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLAT
      220       230       240       250       260       270        

              240       250       260       270       280       290
pF1KB3 PELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGTPY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::
XP_011 PELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPY
      280       290       300       310       320       330        

              300       310       320       330       340       350
pF1KB3 DLAIDMWSLGCILVEMHTGEPLFSGSNEVDQMNRIVEVLGIPPAAMLDQAPKARKYFERL
       :::::::::::::::::::::::::.:::::::.:::::::::: .:::::::::.::.:
XP_011 DLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIPPAHILDQAPKARKFFEKL
      340       350       360       370       380       390        

              360       370       380       390       400       410
pF1KB3 PGGGWTLRRTKELRKDYQGPGTRRLQEVLGVQTGGPGGRRAGEPGHSPADYLRFQDLVLR
       : : :.:..::. ...:. ::::.:...:::.::::::::::: ::. ::::.:.::.::
XP_011 PDGTWNLKKTKDGKREYKPPGTRKLHNILGVETGGPGGRRAGESGHTVADYLKFKDLILR
      400       410       420       430       440       450        

              420       430       440       450       460       470
pF1KB3 MLEYEPAARISPLGALQHGFFRRTADEATNTGPAGSSASTSPAPLDTCPSSSTASSISSS
       ::.:.: .::.:  ::::.::..::::.:::   ..:.:::::  ..  :..:.:. :::
XP_011 MLDYDPKTRIQPYYALQHSFFKKTADEGTNT---SNSVSTSPAMEQSQSSGTTSSTSSSS
      460       470       480          490       500       510     

              480          490          500       510         520  
pF1KB3 GGSSGSSSDNRTYR---YSNRYCGG---PGPPITDCEMNSPQVPPSQPLRP--WAGGDVP
       :::::.:...:.     ...:. ::    .    ::: .::::  . :  :  :.: ..:
XP_011 GGSSGTSNSGRARSDPTHQHRHSGGHFTAAVQAMDCETHSPQVRQQFPA-PLGWSGTEAP
         520       530       540       550       560        570    

            530       540       550       560       570       580  
pF1KB3 HKTHQAPASASSLPGTGAQLPPQPRYLGRPPSPTSPPPPELMDVSLVGGPADCSPPHPAP
           :. . .  .  :  .. ::   :                                 
XP_011 T---QVTVETHPVQETTFHVAPQQNALHHHHGNSSHHHHHHHHHHHHHGQQALGNRTRPR
             580       590       600       610       620       630 

>>NP_001387 (OMIM: 600855,614104) dual specificity tyros  (763 aa)
 initn: 2472 init1: 2446 opt: 2538  Z-score: 937.1  bits: 183.8 E(85289): 1.9e-45
Smith-Waterman score: 2538; 71.3% identity (87.0% similar) in 537 aa overlap (21-549:69-598)

                         10        20        30        40        50
pF1KB3           MAVPPGHGPFSGFPGPQEHTQVLPDVRLLPRRLPLAFRDATSAPLRKLSV
                                     ::.::. .: ::.: .::: ..::::::::
NP_001 QYSDRRQPNISDQQVSALSYSDQIQQPLTNQVMPDIVMLQRRMPQTFRDPATAPLRKLSV
       40        50        60        70        80        90        

               60        70        80        90       100       110
pF1KB3 DLIKTYKHINEVYYAKKKRRAQQAPPQDSSNKKEKKVLNHGYDDDNHDYIVRSGERWLER
       :::::::::::::::::::: ::.  .:::.:::.:: : ::::::.::::..::.:..:
NP_001 DLIKTYKHINEVYYAKKKRRHQQGQGDDSSHKKERKVYNDGYDDDNYDYIVKNGEKWMDR
      100       110       120       130       140       150        

              120       130       140       150       160       170
pF1KB3 YEIDSLIGKGSFGQVVKAYDHQTQELVAIKIIKNKKAFLNQAQIELRLLELMNQHDTEMK
       ::::::::::::::::::::.  :: :::::::::::::::::::.:::::::.::::::
NP_001 YEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMK
      160       170       180       190       200       210        

              180       190       200       210       220       230
pF1KB3 YYIVHLKRHFMFRNHLCLVFELLSYNLYDLLRNTHFRGVSLNLTRKLAQQLCTALLFLAT
       :::::::::::::::::::::.::::::::::::.:::::::::::.:::.:::::::::
NP_001 YYIVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLAT
      220       230       240       250       260       270        

              240       250       260       270       280       290
pF1KB3 PELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGTPY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::
NP_001 PELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPY
      280       290       300       310       320       330        

              300       310       320       330       340       350
pF1KB3 DLAIDMWSLGCILVEMHTGEPLFSGSNEVDQMNRIVEVLGIPPAAMLDQAPKARKYFERL
       :::::::::::::::::::::::::.:::::::.:::::::::: .:::::::::.::.:
NP_001 DLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIPPAHILDQAPKARKFFEKL
      340       350       360       370       380       390        

              360       370       380       390       400       410
pF1KB3 PGGGWTLRRTKELRKDYQGPGTRRLQEVLGVQTGGPGGRRAGEPGHSPADYLRFQDLVLR
       : : :.:..::. ...:. ::::.:...:::.::::::::::: ::. ::::.:.::.::
NP_001 PDGTWNLKKTKDGKREYKPPGTRKLHNILGVETGGPGGRRAGESGHTVADYLKFKDLILR
      400       410       420       430       440       450        

              420       430       440       450       460       470
pF1KB3 MLEYEPAARISPLGALQHGFFRRTADEATNTGPAGSSASTSPAPLDTCPSSSTASSISSS
       ::.:.: .::.:  ::::.::..::::.:::   ..:.:::::  ..  :..:.:. :::
NP_001 MLDYDPKTRIQPYYALQHSFFKKTADEGTNT---SNSVSTSPAMEQSQSSGTTSSTSSSS
      460       470       480          490       500       510     

              480          490          500       510         520  
pF1KB3 GGSSGSSSDNRTYR---YSNRYCGG---PGPPITDCEMNSPQVPPSQPLRP--WAGGDVP
       :::::.:...:.     ...:. ::    .    ::: .::::  . :  :  :.: ..:
NP_001 GGSSGTSNSGRARSDPTHQHRHSGGHFTAAVQAMDCETHSPQVRQQFPA-PLGWSGTEAP
         520       530       540       550       560        570    

            530       540       550       560       570       580  
pF1KB3 HKTHQAPASASSLPGTGAQLPPQPRYLGRPPSPTSPPPPELMDVSLVGGPADCSPPHPAP
           :. . .  .  :  .. ::   :                                 
NP_001 T---QVTVETHPVQETTFHVAPQQNALHHHHGNSSHHHHHHHHHHHHHGQQALGNRTRPR
             580       590       600       610       620       630 

>>XP_011527784 (OMIM: 600855,614104) PREDICTED: dual spe  (770 aa)
 initn: 2472 init1: 2446 opt: 2538  Z-score: 937.1  bits: 183.9 E(85289): 1.9e-45
Smith-Waterman score: 2538; 71.3% identity (87.0% similar) in 537 aa overlap (21-549:76-605)

                         10        20        30        40        50
pF1KB3           MAVPPGHGPFSGFPGPQEHTQVLPDVRLLPRRLPLAFRDATSAPLRKLSV
                                     ::.::. .: ::.: .::: ..::::::::
XP_011 QYSDRRQPNISDQQVSALSYSDQIQQPLTNQVMPDIVMLQRRMPQTFRDPATAPLRKLSV
          50        60        70        80        90       100     

               60        70        80        90       100       110
pF1KB3 DLIKTYKHINEVYYAKKKRRAQQAPPQDSSNKKEKKVLNHGYDDDNHDYIVRSGERWLER
       :::::::::::::::::::: ::.  .:::.:::.:: : ::::::.::::..::.:..:
XP_011 DLIKTYKHINEVYYAKKKRRHQQGQGDDSSHKKERKVYNDGYDDDNYDYIVKNGEKWMDR
         110       120       130       140       150       160     

              120       130       140       150       160       170
pF1KB3 YEIDSLIGKGSFGQVVKAYDHQTQELVAIKIIKNKKAFLNQAQIELRLLELMNQHDTEMK
       ::::::::::::::::::::.  :: :::::::::::::::::::.:::::::.::::::
XP_011 YEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMK
         170       180       190       200       210       220     

              180       190       200       210       220       230
pF1KB3 YYIVHLKRHFMFRNHLCLVFELLSYNLYDLLRNTHFRGVSLNLTRKLAQQLCTALLFLAT
       :::::::::::::::::::::.::::::::::::.:::::::::::.:::.:::::::::
XP_011 YYIVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLAT
         230       240       250       260       270       280     

              240       250       260       270       280       290
pF1KB3 PELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGTPY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::
XP_011 PELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPY
         290       300       310       320       330       340     

              300       310       320       330       340       350
pF1KB3 DLAIDMWSLGCILVEMHTGEPLFSGSNEVDQMNRIVEVLGIPPAAMLDQAPKARKYFERL
       :::::::::::::::::::::::::.:::::::.:::::::::: .:::::::::.::.:
XP_011 DLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIPPAHILDQAPKARKFFEKL
         350       360       370       380       390       400     

              360       370       380       390       400       410
pF1KB3 PGGGWTLRRTKELRKDYQGPGTRRLQEVLGVQTGGPGGRRAGEPGHSPADYLRFQDLVLR
       : : :.:..::. ...:. ::::.:...:::.::::::::::: ::. ::::.:.::.::
XP_011 PDGTWNLKKTKDGKREYKPPGTRKLHNILGVETGGPGGRRAGESGHTVADYLKFKDLILR
         410       420       430       440       450       460     

              420       430       440       450       460       470
pF1KB3 MLEYEPAARISPLGALQHGFFRRTADEATNTGPAGSSASTSPAPLDTCPSSSTASSISSS
       ::.:.: .::.:  ::::.::..::::.:::   ..:.:::::  ..  :..:.:. :::
XP_011 MLDYDPKTRIQPYYALQHSFFKKTADEGTNT---SNSVSTSPAMEQSQSSGTTSSTSSSS
         470       480       490          500       510       520  

              480          490          500       510         520  
pF1KB3 GGSSGSSSDNRTYR---YSNRYCGG---PGPPITDCEMNSPQVPPSQPLRP--WAGGDVP
       :::::.:...:.     ...:. ::    .    ::: .::::  . :  :  :.: ..:
XP_011 GGSSGTSNSGRARSDPTHQHRHSGGHFTAAVQAMDCETHSPQVRQQFPA-PLGWSGTEAP
            530       540       550       560       570        580 

            530       540       550       560       570       580  
pF1KB3 HKTHQAPASASSLPGTGAQLPPQPRYLGRPPSPTSPPPPELMDVSLVGGPADCSPPHPAP
           :. . .  .  :  .. ::   :                                 
XP_011 T---QVTVETHPVQETTFHVAPQQNALHHHHGNSSHHHHHHHHHHHHHGQQALGNRTRPR
                590       600       610       620       630        




629 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 14:12:03 2016 done: Thu Nov  3 14:12:05 2016
 Total Scan time: 14.200 Total Display time:  0.150

Function used was FASTA [36.3.4 Apr, 2011]
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