FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3985, 336 aa 1>>>pF1KB3985 336 - 336 aa - 336 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.8425+/-0.00078; mu= 10.3164+/- 0.047 mean_var=130.5212+/-25.911, 0's: 0 Z-trim(112.8): 60 B-trim: 179 in 2/51 Lambda= 0.112262 statistics sampled from 13480 (13541) to 13480 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.76), E-opt: 0.2 (0.416), width: 16 Scan time: 2.880 The best scores are: opt bits E(32554) CCDS673.1 ST6GALNAC5 gene_id:81849|Hs108|chr1 ( 336) 2349 391.2 6.3e-109 CCDS69668.1 ST6GALNAC6 gene_id:30815|Hs108|chr9 ( 299) 951 164.8 8.3e-41 CCDS6882.1 ST6GALNAC6 gene_id:30815|Hs108|chr9 ( 333) 951 164.8 9e-41 CCDS6883.1 ST6GALNAC4 gene_id:27090|Hs108|chr9 ( 302) 850 148.4 7e-36 CCDS672.1 ST6GALNAC3 gene_id:256435|Hs108|chr1 ( 305) 766 134.8 8.8e-32 CCDS69669.1 ST6GALNAC6 gene_id:30815|Hs108|chr9 ( 374) 705 125.0 9.7e-29 >>CCDS673.1 ST6GALNAC5 gene_id:81849|Hs108|chr1 (336 aa) initn: 2349 init1: 2349 opt: 2349 Z-score: 2069.1 bits: 391.2 E(32554): 6.3e-109 Smith-Waterman score: 2349; 100.0% identity (100.0% similar) in 336 aa overlap (1-336:1-336) 10 20 30 40 50 60 pF1KB3 MKTLMRHGLAVCLALTTMCTSLLLVYSSLGGQKERPPQQQQQQQQQQQQASATGSSQPAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS67 MKTLMRHGLAVCLALTTMCTSLLLVYSSLGGQKERPPQQQQQQQQQQQQASATGSSQPAA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 ESSTQQRPGVPAGPRPLDGYLGVADHKPLKMHCRDCALVTSSGHLLHSRQGSQIDQTECV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS67 ESSTQQRPGVPAGPRPLDGYLGVADHKPLKMHCRDCALVTSSGHLLHSRQGSQIDQTECV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 IRMNDAPTRGYGRDVGNRTSLRVIAHSSIQRILRNRHDLLNVSQGTVFIFWGPSSYMRRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS67 IRMNDAPTRGYGRDVGNRTSLRVIAHSSIQRILRNRHDLLNVSQGTVFIFWGPSSYMRRD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 GKGQVYNNLHLLSQVLPRLKAFMITRHKMLQFDELFKQETGKDRKISNTWLSTGWFTMTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS67 GKGQVYNNLHLLSQVLPRLKAFMITRHKMLQFDELFKQETGKDRKISNTWLSTGWFTMTI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 ALELCDRINVYGMVPPDFCRDPNHPSVPYHYYEPFGPDECTMYLSHERGRKGSHHRFITE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS67 ALELCDRINVYGMVPPDFCRDPNHPSVPYHYYEPFGPDECTMYLSHERGRKGSHHRFITE 250 260 270 280 290 300 310 320 330 pF1KB3 KRVFKNWARTFNIHFFQPDWKPESLAINHPENKPVF :::::::::::::::::::::::::::::::::::: CCDS67 KRVFKNWARTFNIHFFQPDWKPESLAINHPENKPVF 310 320 330 >>CCDS69668.1 ST6GALNAC6 gene_id:30815|Hs108|chr9 (299 aa) initn: 844 init1: 553 opt: 951 Z-score: 846.1 bits: 164.8 E(32554): 8.3e-41 Smith-Waterman score: 951; 52.0% identity (81.1% similar) in 244 aa overlap (78-320:56-298) 50 60 70 80 90 100 pF1KB3 QQASATGSSQPAAESSTQQRPGVPAGPRPLDGYLGVADHKPLKMHCRDCALVTSSGHLLH :::. . .: : .:..:..:.::.::: CCDS69 SSNSANEVFHYGSLRGRSRRPVNLKKWSITDGYVPILGNKTLPSRCHQCVIVSSSSHLLG 30 40 50 60 70 80 110 120 130 140 150 160 pF1KB3 SRQGSQIDQTECVIRMNDAPTRGYGRDVGNRTSLRVIAHSSIQRILRNRHDLLNVSQGTV .. : .:...::.:::::::: ::. ::::.:. ::.::::. :.:: ....: . :: CCDS69 TKLGPEIERAECTIRMNDAPTTGYSADVGNKTTYRVVAHSSVFRVLRRPQEFVNRTPETV 90 100 110 120 130 140 170 180 190 200 210 220 pF1KB3 FIFWGPSSYMRRDGKGQVYNNLHLLSQVLPRLKAFMITRHKMLQFDELFKQETGKDRKIS :::::: : :.. .:.. .. . :.: ..:. .. .: :::.::. ::::::. : CCDS69 FIFWGPPSKMQKP-QGSLVRVIQRAGLVFPNMEAYAVSPGRMRQFDDLFRGETGKDREKS 150 160 170 180 190 200 230 240 250 260 270 280 pF1KB3 NTWLSTGWFTMTIALELCDRINVYGMVPPDFCRD-PNHPSVPYHYYEPFGPDECTMYLSH ..:::::::::.::.::::...:::::::..: . : .::::::: :::::. :... CCDS69 HSWLSTGWFTMVIAVELCDHVHVYGMVPPNYCSQRPRLQRMPYHYYEPKGPDECVTYIQN 210 220 230 240 250 260 290 300 310 320 330 pF1KB3 ERGRKGSHHRFITEKRVFKNWARTFNIHFFQPDWKPESLAINHPENKPVF :..:::.:::::::::::..::. ..: : .:.: CCDS69 EHSRKGNHHRFITEKRVFSSWAQLYGITFSHPSWT 270 280 290 >>CCDS6882.1 ST6GALNAC6 gene_id:30815|Hs108|chr9 (333 aa) initn: 868 init1: 553 opt: 951 Z-score: 845.4 bits: 164.8 E(32554): 9e-41 Smith-Waterman score: 951; 52.0% identity (81.1% similar) in 244 aa overlap (78-320:90-332) 50 60 70 80 90 100 pF1KB3 QQASATGSSQPAAESSTQQRPGVPAGPRPLDGYLGVADHKPLKMHCRDCALVTSSGHLLH :::. . .: : .:..:..:.::.::: CCDS68 SSNSANEVFHYGSLRGRSRRPVNLKKWSITDGYVPILGNKTLPSRCHQCVIVSSSSHLLG 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB3 SRQGSQIDQTECVIRMNDAPTRGYGRDVGNRTSLRVIAHSSIQRILRNRHDLLNVSQGTV .. : .:...::.:::::::: ::. ::::.:. ::.::::. :.:: ....: . :: CCDS68 TKLGPEIERAECTIRMNDAPTTGYSADVGNKTTYRVVAHSSVFRVLRRPQEFVNRTPETV 120 130 140 150 160 170 170 180 190 200 210 220 pF1KB3 FIFWGPSSYMRRDGKGQVYNNLHLLSQVLPRLKAFMITRHKMLQFDELFKQETGKDRKIS :::::: : :.. .:.. .. . :.: ..:. .. .: :::.::. ::::::. : CCDS68 FIFWGPPSKMQKP-QGSLVRVIQRAGLVFPNMEAYAVSPGRMRQFDDLFRGETGKDREKS 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB3 NTWLSTGWFTMTIALELCDRINVYGMVPPDFCRD-PNHPSVPYHYYEPFGPDECTMYLSH ..:::::::::.::.::::...:::::::..: . : .::::::: :::::. :... CCDS68 HSWLSTGWFTMVIAVELCDHVHVYGMVPPNYCSQRPRLQRMPYHYYEPKGPDECVTYIQN 240 250 260 270 280 290 290 300 310 320 330 pF1KB3 ERGRKGSHHRFITEKRVFKNWARTFNIHFFQPDWKPESLAINHPENKPVF :..:::.:::::::::::..::. ..: : .:.: CCDS68 EHSRKGNHHRFITEKRVFSSWAQLYGITFSHPSWT 300 310 320 330 >>CCDS6883.1 ST6GALNAC4 gene_id:27090|Hs108|chr9 (302 aa) initn: 822 init1: 690 opt: 850 Z-score: 757.6 bits: 148.4 E(32554): 7e-36 Smith-Waterman score: 850; 47.9% identity (75.5% similar) in 261 aa overlap (64-323:44-302) 40 50 60 70 80 90 pF1KB3 ERPPQQQQQQQQQQQQASATGSSQPAAESSTQQRPGVPAGPRPLDGYLGVADHKPL-KMH : .:: :: :: ..:: .: : ::: . CCDS68 SVVFSAVYILLCCWAGLPLCLATCLDHHFPTGSRPTVP-GPLHFSGYSSVPDGKPLVREP 20 30 40 50 60 70 100 110 120 130 140 150 pF1KB3 CRDCALVTSSGHLLHSRQGSQIDQTECVIRMNDAPTRGYGRDVGNRTSLRVIAHSSIQRI ::.::.:.:::..: : :..::..:::.:::.::: :. :::.:..:::..:.:. . CCDS68 CRSCAVVSSSGQMLGSGLGAEIDSAECVFRMNQAPTVGFEADVGQRSTLRVVSHTSVPLL 80 90 100 110 120 130 160 170 180 190 200 210 pF1KB3 LRNRHDLLNVSQGTVFIFWGPSSYMRRDGKGQVYNNLHLLSQVLPRLKAFMITRHKMLQF ::: .. .. :... :: . .: : :..: .: :... : :... .:.. : CCDS68 LRNYSHYFQKARDTLYMVWGQGRHMDRVLGGRTYRTLLQLTRMYPGLQVYTFTERMMAYC 140 150 160 170 180 190 220 230 240 250 260 270 pF1KB3 DELFKQETGKDRKISNTWLSTGWFTMTIALELCDRINVYGMVPPDFCRDPNHPSVPYHYY :..:..::::.:. :...:::::::: .:::::..: ::::: ..::. .::::::::. CCDS68 DQIFQDETGKNRRQSGSFLSTGWFTMILALELCEEIVVYGMVSDSYCREKSHPSVPYHYF 200 210 220 230 240 250 280 290 300 310 320 330 pF1KB3 EPFGPDECTMYLSHERGRKGSHHRFITEKRVFKNWARTFNIHFFQPDWKPESLAINHPEN : ::: :::.::.. . : ::::::: ::. ::. : : .:.:. : CCDS68 EKGRLDECQMYLAHEQAPR-SAHRFITEKAVFSRWAKKRPIVFAHPSWRTE 260 270 280 290 300 pF1KB3 KPVF >>CCDS672.1 ST6GALNAC3 gene_id:256435|Hs108|chr1 (305 aa) initn: 756 init1: 616 opt: 766 Z-score: 684.0 bits: 134.8 E(32554): 8.8e-32 Smith-Waterman score: 766; 43.0% identity (72.3% similar) in 249 aa overlap (75-320:56-302) 50 60 70 80 90 100 pF1KB3 QQQQQASATGSSQPAAESSTQQRPGVPAGPRPLD---GYLGVADHKPLKMHCRDCALVTS ::: ::..: ..::.. : ::.:.. CCDS67 RLVNEVNFPLLLNCFGQPGTKWIPFSYTYRRPLRTHYGYINVKTQEPLQLDCDLCAIVSN 30 40 50 60 70 80 110 120 130 140 150 160 pF1KB3 SGHLLHSRQGSQIDQTECVIRMNDAPTRGYGRDVGNRTSLRVIAHSSIQRILRNRHDLLN ::... .. :..::.. :. :::.:::.:: .::: : .::..:.:. .:.: ... CCDS67 SGQMVGQKVGNEIDRSSCIWRMNNAPTKGYEEDVGRMTMIRVVSHTSVPLLLKNPDYFFK 90 100 110 120 130 140 170 180 190 200 210 220 pF1KB3 VSQGTVFIFWGPSSYMRRDGKGQVYNNLHLLSQVLPRLKAFMITRHKMLQFDELFKQETG .. :....::: ::.::.: ::: :. . : . .. :...: : .::.::: CCDS67 EANTTIYVIWGPFRNMRKDGNGIVYNMLKKTVGIYPNAQIYVTTEKRMSYCDGVFKKETG 150 160 170 180 190 200 230 240 250 260 270 280 pF1KB3 KDRKISNTWLSTGWFTMTIALELCDRINVYGMVPPDFCRDPNHPSVPYHYYEPFGPDECT ::: :...:::::::. .:.. : :.::::. .:. .. .::::::: : ::: CCDS67 KDRVQSGSYLSTGWFTFLLAMDACYGIHVYGMINDTYCKTEGYRKVPYHYYEQ-GRDECD 210 220 230 240 250 260 290 300 310 320 330 pF1KB3 MYLSHERGRKGSHHRFITEKRVFKNWARTFNIHFFQPDWKPESLAINHPENKPVF :. ::.. :.: ::::::.:: .::. : : .:.: CCDS67 EYFLHEHAPYGGH-RFITEKKVFAKWAKKHRIIFTHPNWTLS 270 280 290 300 >>CCDS69669.1 ST6GALNAC6 gene_id:30815|Hs108|chr9 (374 aa) initn: 720 init1: 382 opt: 705 Z-score: 629.4 bits: 125.0 E(32554): 9.7e-29 Smith-Waterman score: 706; 45.9% identity (71.6% similar) in 229 aa overlap (78-296:90-317) 50 60 70 80 90 100 pF1KB3 QQASATGSSQPAAESSTQQRPGVPAGPRPLDGYLGVADHKPLKMHCRDCALVTSSGHLLH :::. . .: : .:..:..:.::.::: CCDS69 SSNSANEVFHYGSLRGRSRRPVNLKKWSITDGYVPILGNKTLPSRCHQCVIVSSSSHLLG 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB3 SRQGSQIDQTECVIRMNDAPTRGYGRDVGNRTSLRVIAHSSIQRILRNRHDLLNVSQGTV .. : .:...::.:::::::: ::. ::::.:. ::.::::. :.:: ....: . :: CCDS69 TKLGPEIERAECTIRMNDAPTTGYSADVGNKTTYRVVAHSSVFRVLRRPQEFVNRTPETV 120 130 140 150 160 170 170 180 190 200 210 220 pF1KB3 FIFWGPSSYMRRDGKGQVYNNLHLLSQVLPRLKAFMITRHKMLQFDELFKQETGKDRKIS :::::: : :.. .:.. .. . :.: ..:. .. .: :::.::. ::::::. : CCDS69 FIFWGPPSKMQKP-QGSLVRVIQRAGLVFPNMEAYAVSPGRMRQFDDLFRGETGKDREKS 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB3 NTWLSTGWFTMTIALELCDRINVYGMVPPDFCRDPNHPSVPYHYYEPFGPDEC--TMYLS ..:::::::::.::.::::...:::::::..: : . : : : . : .: CCDS69 HSWLSTGWFTMVIAVELCDHVHVYGMVPPNYCSGPASSACPTTTTSPRGRTNVSPTSRMS 240 250 260 270 280 290 290 300 310 320 330 pF1KB3 H-ERG-------RKGSHHRFITEKRVFKNWARTFNIHFFQPDWKPESLAINHPENKPVF :. :::: :: CCDS69 TVARATTTASSPRKGSSHRGPSCMASPSPTPPGPRPPSLWDLRRVRGEAASAQPLGQGPS 300 310 320 330 340 350 336 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 05:30:44 2016 done: Sat Nov 5 05:30:45 2016 Total Scan time: 2.880 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]