FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB3987, 381 aa 1>>>pF1KB3987 381 - 381 aa - 381 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.5509+/-0.000438; mu= 22.0371+/- 0.027 mean_var=76.3440+/-15.137, 0's: 0 Z-trim(111.8): 96 B-trim: 765 in 1/51 Lambda= 0.146787 statistics sampled from 20450 (20557) to 20450 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.601), E-opt: 0.2 (0.241), width: 16 Scan time: 7.390 The best scores are: opt bits E(85289) NP_031379 (OMIM: 604394) guanine nucleotide-bindin ( 381) 2496 538.2 1.2e-152 XP_011513590 (OMIM: 604394) PREDICTED: guanine nuc ( 284) 1850 401.3 1.5e-111 NP_001269370 (OMIM: 604394) guanine nucleotide-bin ( 322) 1848 400.9 2.2e-111 XP_016867497 (OMIM: 604394) PREDICTED: guanine nuc ( 253) 1670 363.1 4.1e-100 NP_006563 (OMIM: 604406) guanine nucleotide-bindin ( 377) 1575 343.2 6.1e-94 NP_001269369 (OMIM: 604394) guanine nucleotide-bin ( 305) 1372 300.1 4.6e-81 NP_001280021 (OMIM: 604394) guanine nucleotide-bin ( 364) 1261 276.7 6.2e-74 NP_001269354 (OMIM: 604406) guanine nucleotide-bin ( 282) 1254 275.1 1.5e-73 NP_002063 (OMIM: 163000,185300,600998) guanine nuc ( 359) 999 221.2 3.1e-57 NP_002058 (OMIM: 139313) guanine nucleotide-bindin ( 359) 978 216.7 6.7e-56 NP_004288 (OMIM: 604397) guanine nucleotide-bindin ( 355) 948 210.4 5.5e-54 NP_066268 (OMIM: 139311,615473) guanine nucleotide ( 354) 933 207.2 4.9e-53 NP_001095856 (OMIM: 139395) guanine nucleotide-bin ( 354) 932 207.0 5.7e-53 XP_011539566 (OMIM: 139340,613856) PREDICTED: guan ( 354) 916 203.6 6e-52 NP_005263 (OMIM: 139340,613856) guanine nucleotide ( 354) 916 203.6 6e-52 NP_620073 (OMIM: 139311,615473) guanine nucleotide ( 354) 914 203.2 8e-52 NP_002060 (OMIM: 139310) guanine nucleotide-bindin ( 354) 912 202.7 1.1e-51 NP_006487 (OMIM: 139370,602483) guanine nucleotide ( 354) 902 200.6 4.7e-51 NP_002064 (OMIM: 139160) guanine nucleotide-bindin ( 355) 895 199.1 1.3e-50 NP_653082 (OMIM: 139330,610444,616389) guanine nuc ( 350) 880 196.0 1.2e-49 NP_000163 (OMIM: 139330,610444,616389) guanine nuc ( 350) 880 196.0 1.2e-49 NP_002061 (OMIM: 139360,192605) guanine nucleotide ( 355) 871 194.1 4.4e-49 XP_016870117 (OMIM: 163000,185300,600998) PREDICTE ( 301) 842 187.8 2.8e-47 NP_001159897 (OMIM: 139360,192605) guanine nucleot ( 318) 813 181.7 2e-45 NP_001269549 (OMIM: 139360,192605) guanine nucleot ( 339) 813 181.8 2.1e-45 NP_001269548 (OMIM: 139360,192605) guanine nucleot ( 339) 813 181.8 2.1e-45 XP_011521305 (OMIM: 139311,615473) PREDICTED: guan ( 312) 806 180.2 5.6e-45 NP_002059 (OMIM: 139314) guanine nucleotide-bindin ( 374) 804 179.9 8.5e-45 XP_016870830 (OMIM: 604397) PREDICTED: guanine nuc ( 301) 795 177.9 2.8e-44 NP_001243343 (OMIM: 139310) guanine nucleotide-bin ( 302) 787 176.2 9e-44 XP_011514426 (OMIM: 139395) PREDICTED: guanine nuc ( 297) 775 173.6 5.2e-43 NP_001269546 (OMIM: 139360,192605) guanine nucleot ( 303) 743 166.9 5.7e-41 XP_011517526 (OMIM: 604397) PREDICTED: guanine nuc ( 237) 735 165.1 1.6e-40 NP_001070957 (OMIM: 102200,103580,139320,166350,17 ( 379) 719 161.9 2.3e-39 NP_536351 (OMIM: 102200,103580,139320,166350,17480 ( 380) 716 161.3 3.5e-39 XP_016883303 (OMIM: 102200,103580,139320,166350,17 (1022) 720 162.6 3.8e-39 NP_001269547 (OMIM: 139360,192605) guanine nucleot ( 274) 712 160.3 5.1e-39 XP_016883302 (OMIM: 102200,103580,139320,166350,17 (1023) 717 161.9 5.9e-39 NP_892023 (OMIM: 139312,615073) guanine nucleotide ( 458) 712 160.5 7.2e-39 NP_001135811 (OMIM: 139312,615073) guanine nucleot ( 381) 681 153.9 6e-37 NP_001248372 (OMIM: 139312,615073) guanine nucleot ( 381) 681 153.9 6e-37 XP_016883304 (OMIM: 102200,103580,139320,166350,17 ( 347) 666 150.6 5.1e-36 XP_011522504 (OMIM: 604406) PREDICTED: guanine nuc ( 203) 660 149.1 8.6e-36 XP_016883306 (OMIM: 102200,103580,139320,166350,17 ( 320) 590 134.5 3.4e-31 XP_016883307 (OMIM: 102200,103580,139320,166350,17 ( 320) 590 134.5 3.4e-31 XP_016883308 (OMIM: 102200,103580,139320,166350,17 ( 320) 590 134.5 3.4e-31 XP_016884275 (OMIM: 139160) PREDICTED: guanine nuc ( 307) 576 131.5 2.6e-30 XP_016883305 (OMIM: 102200,103580,139320,166350,17 ( 320) 567 129.6 9.9e-30 XP_016883309 (OMIM: 102200,103580,139320,166350,17 ( 320) 567 129.6 9.9e-30 NP_001296790 (OMIM: 102200,103580,139320,166350,17 ( 335) 567 129.6 1e-29 >>NP_031379 (OMIM: 604394) guanine nucleotide-binding pr (381 aa) initn: 2496 init1: 2496 opt: 2496 Z-score: 2861.6 bits: 538.2 E(85289): 1.2e-152 Smith-Waterman score: 2496; 100.0% identity (100.0% similar) in 381 aa overlap (1-381:1-381) 10 20 30 40 50 60 pF1KB3 MSGVVRTLSRCLLPAEAGGARERRAGSGARDAEREARRRSRDIDALLARERRAVRRLVKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_031 MSGVVRTLSRCLLPAEAGGARERRAGSGARDAEREARRRSRDIDALLARERRAVRRLVKI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 LLLGAGESGKSTFLKQMRIIHGREFDQKALLEFRDTIFDNILKGSRVLVDARDKLGIPWQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_031 LLLGAGESGKSTFLKQMRIIHGREFDQKALLEFRDTIFDNILKGSRVLVDARDKLGIPWQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 YSENEKHGMFLMAFENKAGLPVEPATFQLYVPALSALWRDSGIREAFSRRSEFQLGESVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_031 YSENEKHGMFLMAFENKAGLPVEPATFQLYVPALSALWRDSGIREAFSRRSEFQLGESVK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB3 YFLDNLDRIGQLNYFPSKQDILLARKATKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_031 YFLDNLDRIGQLNYFPSKQDILLARKATKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB3 CFDGITSILFMVSSSEYDQVLMEDRRTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_031 CFDGITSILFMVSSSEYDQVLMEDRRTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB3 LVEKVKTVSIKKHFPDFRGDPHRLEDVQRYLVQCFDRKRRNRSKPLFHHFTTAIDTENVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_031 LVEKVKTVSIKKHFPDFRGDPHRLEDVQRYLVQCFDRKRRNRSKPLFHHFTTAIDTENVR 310 320 330 340 350 360 370 380 pF1KB3 FVFHAVKDTILQENLKDIMLQ ::::::::::::::::::::: NP_031 FVFHAVKDTILQENLKDIMLQ 370 380 >>XP_011513590 (OMIM: 604394) PREDICTED: guanine nucleot (284 aa) initn: 1850 init1: 1850 opt: 1850 Z-score: 2123.8 bits: 401.3 E(85289): 1.5e-111 Smith-Waterman score: 1850; 98.9% identity (99.6% similar) in 281 aa overlap (101-381:4-284) 80 90 100 110 120 130 pF1KB3 STFLKQMRIIHGREFDQKALLEFRDTIFDNILKGSRVLVDARDKLGIPWQYSENEKHGMF . .::::::::::::::::::::::::::: XP_011 MTKVTQGSRVLVDARDKLGIPWQYSENEKHGMF 10 20 30 140 150 160 170 180 190 pF1KB3 LMAFENKAGLPVEPATFQLYVPALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LMAFENKAGLPVEPATFQLYVPALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIG 40 50 60 70 80 90 200 210 220 230 240 250 pF1KB3 QLNYFPSKQDILLARKATKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QLNYFPSKQDILLARKATKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILF 100 110 120 130 140 150 260 270 280 290 300 310 pF1KB3 MVSSSEYDQVLMEDRRTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKTVSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MVSSSEYDQVLMEDRRTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKTVSI 160 170 180 190 200 210 320 330 340 350 360 370 pF1KB3 KKHFPDFRGDPHRLEDVQRYLVQCFDRKRRNRSKPLFHHFTTAIDTENVRFVFHAVKDTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KKHFPDFRGDPHRLEDVQRYLVQCFDRKRRNRSKPLFHHFTTAIDTENVRFVFHAVKDTI 220 230 240 250 260 270 380 pF1KB3 LQENLKDIMLQ ::::::::::: XP_011 LQENLKDIMLQ 280 >>NP_001269370 (OMIM: 604394) guanine nucleotide-binding (322 aa) initn: 1848 init1: 1848 opt: 1848 Z-score: 2120.8 bits: 400.9 E(85289): 2.2e-111 Smith-Waterman score: 1848; 99.6% identity (100.0% similar) in 279 aa overlap (103-381:44-322) 80 90 100 110 120 130 pF1KB3 FLKQMRIIHGREFDQKALLEFRDTIFDNILKGSRVLVDARDKLGIPWQYSENEKHGMFLM .::::::::::::::::::::::::::::: NP_001 MPGSRGSGSTPDGNRKCCRFEHLLIAHPGSRGSRVLVDARDKLGIPWQYSENEKHGMFLM 20 30 40 50 60 70 140 150 160 170 180 190 pF1KB3 AFENKAGLPVEPATFQLYVPALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AFENKAGLPVEPATFQLYVPALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQL 80 90 100 110 120 130 200 210 220 230 240 250 pF1KB3 NYFPSKQDILLARKATKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NYFPSKQDILLARKATKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMV 140 150 160 170 180 190 260 270 280 290 300 310 pF1KB3 SSSEYDQVLMEDRRTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKTVSIKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSSEYDQVLMEDRRTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKTVSIKK 200 210 220 230 240 250 320 330 340 350 360 370 pF1KB3 HFPDFRGDPHRLEDVQRYLVQCFDRKRRNRSKPLFHHFTTAIDTENVRFVFHAVKDTILQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HFPDFRGDPHRLEDVQRYLVQCFDRKRRNRSKPLFHHFTTAIDTENVRFVFHAVKDTILQ 260 270 280 290 300 310 380 pF1KB3 ENLKDIMLQ ::::::::: NP_001 ENLKDIMLQ 320 >>XP_016867497 (OMIM: 604394) PREDICTED: guanine nucleot (253 aa) initn: 1670 init1: 1670 opt: 1670 Z-score: 1918.4 bits: 363.1 E(85289): 4.1e-100 Smith-Waterman score: 1670; 100.0% identity (100.0% similar) in 253 aa overlap (129-381:1-253) 100 110 120 130 140 150 pF1KB3 DNILKGSRVLVDARDKLGIPWQYSENEKHGMFLMAFENKAGLPVEPATFQLYVPALSALW :::::::::::::::::::::::::::::: XP_016 MFLMAFENKAGLPVEPATFQLYVPALSALW 10 20 30 160 170 180 190 200 210 pF1KB3 RDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQLNYFPSKQDILLARKATKGIVEHDFVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQLNYFPSKQDILLARKATKGIVEHDFVI 40 50 60 70 80 90 220 230 240 250 260 270 pF1KB3 KKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLMEDRRTNRLVESMNIFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLMEDRRTNRLVESMNIFE 100 110 120 130 140 150 280 290 300 310 320 330 pF1KB3 TIVNNKLFFNVSIILFLNKMDLLVEKVKTVSIKKHFPDFRGDPHRLEDVQRYLVQCFDRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TIVNNKLFFNVSIILFLNKMDLLVEKVKTVSIKKHFPDFRGDPHRLEDVQRYLVQCFDRK 160 170 180 190 200 210 340 350 360 370 380 pF1KB3 RRNRSKPLFHHFTTAIDTENVRFVFHAVKDTILQENLKDIMLQ ::::::::::::::::::::::::::::::::::::::::::: XP_016 RRNRSKPLFHHFTTAIDTENVRFVFHAVKDTILQENLKDIMLQ 220 230 240 250 >>NP_006563 (OMIM: 604406) guanine nucleotide-binding pr (377 aa) initn: 1403 init1: 966 opt: 1575 Z-score: 1807.5 bits: 343.2 E(85289): 6.1e-94 Smith-Waterman score: 1575; 66.7% identity (87.3% similar) in 354 aa overlap (33-381:24-377) 10 20 30 40 50 60 pF1KB3 GVVRTLSRCLLPAEAGGARERRAGSGARDAEREARRRSRDIDALLARERRAVRRLVKILL : : .:.:..:: :.::. :.::::::: NP_006 MADFLPSRSVLSVCFPGCLLTSGEAEQQRKSKEIDKCLSREKTYVKRLVKILL 10 20 30 40 50 70 80 90 100 110 120 pF1KB3 LGAGESGKSTFLKQMRIIHGREFDQKALLEFRDTIFDNILKGSRVLVDARDKLGIPWQYS ::::::::::::::::::::..:::.: ::: ::..:..:: :::::::.:: ::: . NP_006 LGAGESGKSTFLKQMRIIHGQDFDQRAREEFRPTIYSNVIKGMRVLVDAREKLHIPWGDN 60 70 80 90 100 110 130 140 150 160 170 pF1KB3 ENEKHGMFLMAFENKAGLP----VEPATFQLYVPALSALWRDSGIREAFSRRSEFQLGES :..:: .:.:...: . :: .: :.::. ::: ::::..:..:: ::::::: NP_006 SNQQHGDKMMSFDTRAPMAAQGMVETRVFLQYLPAIRALWADSGIQNAYDRRREFQLGES 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB3 VKYFLDNLDRIGQLNYFPSKQDILLARKATKGIVEHDFVIKKIPFKMVDVGGQRSQRQKW :::::::::..:. .:.::.:::::::. :::: :.:: ::..::::::::::::.:..: NP_006 VKYFLDNLDKLGEPDYIPSQQDILLARRPTKGIHEYDFEIKNVPFKMVDVGGQRSERKRW 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB3 FQCFDGITSILFMVSSSEYDQVLMEDRRTNRLVESMNIFETIVNNKLFFNVSIILFLNKM :.:::..:::::.:::::.:::::::: ::::.::.:::::::::..: :::::::::: NP_006 FECFDSVTSILFLVSSSEFDQVLMEDRLTNRLTESLNIFETIVNNRVFSNVSIILFLNKT 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB3 DLLVEKVKTVSIKKHFPDFRGDPHRLEDVQRYLVQCFDRKRRNRS-KPLFHHFTTAIDTE ::: :::. :::: .: .:.:::: :.:::..::.:: :::... :::.:::::::.:: NP_006 DLLEEKVQIVSIKDYFLEFEGDPHCLRDVQKFLVECFRNKRRDQQQKPLYHHFTTAINTE 300 310 320 330 340 350 360 370 380 pF1KB3 NVRFVFHAVKDTILQENLKDIMLQ :.:.::. ::::::..:::..::: NP_006 NIRLVFRDVKDTILHDNLKQLMLQ 360 370 >>NP_001269369 (OMIM: 604394) guanine nucleotide-binding (305 aa) initn: 1360 init1: 1360 opt: 1372 Z-score: 1576.3 bits: 300.1 E(85289): 4.6e-81 Smith-Waterman score: 1372; 84.8% identity (89.8% similar) in 256 aa overlap (127-381:54-305) 100 110 120 130 140 150 pF1KB3 IFDNILKGSRVLVDARDKLGIPWQYSENEKHGM-FLMAFENKAGLPVEPATFQLYVPALS :: : .:. . ... . : : : NP_001 GWEAALSAPPPFCTAWVERTGLVHFLREGGHGACFPLALLHPGSVVSFQMIYPLIVLPLC 30 40 50 60 70 80 160 170 180 190 200 210 pF1KB3 ALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQLNYFPSKQDILLARKATKGIVEHD : :. . ::... . :::::::::::::::::::::::::::::::::::::::: NP_001 ASWHWGLIRKGIV----LFWGESVKYFLDNLDRIGQLNYFPSKQDILLARKATKGIVEHD 90 100 110 120 130 220 230 240 250 260 270 pF1KB3 FVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLMEDRRTNRLVESMN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLMEDRRTNRLVESMN 140 150 160 170 180 190 280 290 300 310 320 330 pF1KB3 IFETIVNNKLFFNVSIILFLNKMDLLVEKVKTVSIKKHFPDFRGDPHRLEDVQRYLVQCF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IFETIVNNKLFFNVSIILFLNKMDLLVEKVKTVSIKKHFPDFRGDPHRLEDVQRYLVQCF 200 210 220 230 240 250 340 350 360 370 380 pF1KB3 DRKRRNRSKPLFHHFTTAIDTENVRFVFHAVKDTILQENLKDIMLQ :::::::::::::::::::::::::::::::::::::::::::::: NP_001 DRKRRNRSKPLFHHFTTAIDTENVRFVFHAVKDTILQENLKDIMLQ 260 270 280 290 300 >>NP_001280021 (OMIM: 604394) guanine nucleotide-binding (364 aa) initn: 1261 init1: 1261 opt: 1261 Z-score: 1448.4 bits: 276.7 E(85289): 6.2e-74 Smith-Waterman score: 2341; 95.5% identity (95.5% similar) in 381 aa overlap (1-381:1-364) 10 20 30 40 50 60 pF1KB3 MSGVVRTLSRCLLPAEAGGARERRAGSGARDAEREARRRSRDIDALLARERRAVRRLVKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSGVVRTLSRCLLPAEAGGARERRAGSGARDAEREARRRSRDIDALLARERRAVRRLVKI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB3 LLLGAGESGKSTFLKQMRIIHGREFDQKALLEFRDTIFDNILKGSRVLVDARDKLGIPWQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLLGAGESGKSTFLKQMRIIHGREFDQKALLEFRDTIFDNILKGSRVLVDARDKLGIPWQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB3 YSENEKHGMFLMAFENKAGLPVEPATFQLYVPALSALWRDSGIREAFSRRSEFQLGESVK ::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YSENEKHGMFLMAFENKAGLPVEPATFQLYVPALSALWRDSGIREAFSRRSEF------- 130 140 150 160 170 190 200 210 220 230 240 pF1KB3 YFLDNLDRIGQLNYFPSKQDILLARKATKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQ :::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ----------QLNYFPSKQDILLARKATKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQ 180 190 200 210 220 250 260 270 280 290 300 pF1KB3 CFDGITSILFMVSSSEYDQVLMEDRRTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CFDGITSILFMVSSSEYDQVLMEDRRTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDL 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB3 LVEKVKTVSIKKHFPDFRGDPHRLEDVQRYLVQCFDRKRRNRSKPLFHHFTTAIDTENVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LVEKVKTVSIKKHFPDFRGDPHRLEDVQRYLVQCFDRKRRNRSKPLFHHFTTAIDTENVR 290 300 310 320 330 340 370 380 pF1KB3 FVFHAVKDTILQENLKDIMLQ ::::::::::::::::::::: NP_001 FVFHAVKDTILQENLKDIMLQ 350 360 >>NP_001269354 (OMIM: 604406) guanine nucleotide-binding (282 aa) initn: 1082 init1: 966 opt: 1254 Z-score: 1441.7 bits: 275.1 E(85289): 1.5e-73 Smith-Waterman score: 1254; 66.5% identity (87.5% similar) in 281 aa overlap (106-381:2-282) 80 90 100 110 120 130 pF1KB3 QMRIIHGREFDQKALLEFRDTIFDNILKGSRVLVDARDKLGIPWQYSENEKHGMFLMAFE :::::::.:: ::: . :..:: .:.:. NP_001 MRVLVDAREKLHIPWGDNSNQQHGDKMMSFD 10 20 30 140 150 160 170 180 190 pF1KB3 NKAGLP----VEPATFQLYVPALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQ ..: . :: .: :.::. ::: ::::..:..:: ::::::::::::::::..:. NP_001 TRAPMAAQGMVETRVFLQYLPAIRALWADSGIQNAYDRRREFQLGESVKYFLDNLDKLGE 40 50 60 70 80 90 200 210 220 230 240 250 pF1KB3 LNYFPSKQDILLARKATKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFM .:.::.:::::::. :::: :.:: ::..::::::::::::.:..::.:::..:::::. NP_001 PDYIPSQQDILLARRPTKGIHEYDFEIKNVPFKMVDVGGQRSERKRWFECFDSVTSILFL 100 110 120 130 140 150 260 270 280 290 300 310 pF1KB3 VSSSEYDQVLMEDRRTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKTVSIK :::::.:::::::: ::::.::.:::::::::..: :::::::::: ::: :::. :::: NP_001 VSSSEFDQVLMEDRLTNRLTESLNIFETIVNNRVFSNVSIILFLNKTDLLEEKVQIVSIK 160 170 180 190 200 210 320 330 340 350 360 370 pF1KB3 KHFPDFRGDPHRLEDVQRYLVQCFDRKRRNRS-KPLFHHFTTAIDTENVRFVFHAVKDTI .: .:.:::: :.:::..::.:: :::... :::.:::::::.:::.:.::. ::::: NP_001 DYFLEFEGDPHCLRDVQKFLVECFRNKRRDQQQKPLYHHFTTAINTENIRLVFRDVKDTI 220 230 240 250 260 270 380 pF1KB3 LQENLKDIMLQ :..:::..::: NP_001 LHDNLKQLMLQ 280 >>NP_002063 (OMIM: 163000,185300,600998) guanine nucleot (359 aa) initn: 1012 init1: 750 opt: 999 Z-score: 1148.6 bits: 221.2 E(85289): 3.1e-57 Smith-Waterman score: 999; 45.0% identity (73.9% similar) in 349 aa overlap (34-380:16-358) 10 20 30 40 50 60 pF1KB3 VVRTLSRCLLPAEAGGARERRAGSGARDAEREARRRSRDIDALLARERRAVRRLVKILLL .:::: . .:. : :..: .:: .:.::: NP_002 MTLESIMACCLSEEAKEARRINDEIERQLRRDKRDARRELKLLLL 10 20 30 40 70 80 90 100 110 120 pF1KB3 GAGESGKSTFLKQMRIIHGREFDQKALLEFRDTIFDNILKGSRVLVDARDKLGIPWQYSE :.::::::::.:::::::: .... : ...::. . .... : : : ::..: . NP_002 GTGESGKSTFIKQMRIIHGSGYSDEDKRGFTKLVYQNIFTAMQAMIRAMDTLKIPYKYEH 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB3 NEKHGMFLMAFE-NKAGLPVEPATFQLYVPALSALWRDSGIREAFSRRSEFQLGESVKYF :. :.... . .:.. .: :: :...:: : ::.: ..:: :.::..:.::. NP_002 NKAHAQLVREVDVEKVSAFENP-----YVDAIKSLWNDPGIQECYDRRREYQLSDSTKYY 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB3 LDNLDRIGQLNYFPSKQDILLARKATKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQCF :..:::... :.:..::.: .: : ::.:. : .... :.:::::::::.:.::..:: NP_002 LNDLDRVADPAYLPTQQDVLRVRVPTTGIIEYPFDLQSVIFRMVDVGGQRSERRKWIHCF 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB3 DGITSILFMVSSSEYDQVLMEDRRTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDLLV ...:::.:.:. :::::::.:. ::. :: .:.::.. : : :.:::::: ::: NP_002 ENVTSIMFLVALSEYDQVLVESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLE 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB3 EKVKTVSIKKHFPDFRGDPHRLEDVQR-YLVQCFDRKRRNRSKPLFHHFTTAIDTENVRF ::. . .::.. : :.: .. : .... : . .: .. ::: : ::::.:: NP_002 EKIMYSHLVDYFPEYDG-PQRDAQAAREFILKMFVDLNPDSDKIIYSHFTCATDTENIRF 290 300 310 320 330 370 380 pF1KB3 VFHAVKDTILQENLKDIMLQ :: :::::::: :::. : NP_002 VFAAVKDTILQLNLKEYNLV 340 350 >>NP_002058 (OMIM: 139313) guanine nucleotide-binding pr (359 aa) initn: 944 init1: 752 opt: 978 Z-score: 1124.5 bits: 216.7 E(85289): 6.7e-56 Smith-Waterman score: 978; 43.9% identity (72.9% similar) in 351 aa overlap (31-380:13-358) 10 20 30 40 50 60 pF1KB3 MSGVVRTLSRCLLPAEAGGARERRAGSGARDAEREARRRSRDIDALLARERRAVRRLVKI : .:..: . .:. : :..: .:: .:. NP_002 MTLESMMACCLSDEVKESKRINAEIEKQLRRDKRDARRELKL 10 20 30 40 70 80 90 100 110 120 pF1KB3 LLLGAGESGKSTFLKQMRIIHGREFDQKALLEFRDTIFDNILKGSRVLVDARDKLGIPWQ ::::.::::::::.:::::::: .... : ...::. . .... : . : : .. NP_002 LLLGTGESGKSTFIKQMRIIHGAGYSEEDKRGFTKLVYQNIFTAMQAMIRAMETLKILYK 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB3 YSENEKHGMFLMAFENKAGLPVEPATFQLYVPALSALWRDSGIREAFSRRSEFQLGESVK : .:. ..... . . : . :: :...::.: ::.: ..:: :.::..:.: NP_002 YEQNKANALLIREVDVEKVTTFE----HQYVSAIKTLWEDPGIQECYDRRREYQLSDSAK 110 120 130 140 150 190 200 210 220 230 240 pF1KB3 YFLDNLDRIGQLNYFPSKQDILLARKATKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQ :.: ..:::. :.:.:..::.: .: : ::.:. : ...: :.:::::::::.:.::.. NP_002 YYLTDVDRIATLGYLPTQQDVLRVRVPTTGIIEYPFDLENIIFRMVDVGGQRSERRKWIH 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB3 CFDGITSILFMVSSSEYDQVLMEDRRTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDL ::...:::.:.:. :::::::.:. ::. :: .:.::.. : : :.:::::: :: NP_002 CFENVTSIMFLVALSEYDQVLVESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDL 220 230 240 250 260 270 310 320 330 340 350 pF1KB3 LVEKVKTVSIKKHFPDFRGDPHRLEDVQR-YLVQCFDRKRRNRSKPLFHHFTTAIDTENV : .:. . .::.: : :.: .. : .... : . .: .. ::: : ::::. NP_002 LEDKILYSHLVDYFPEFDG-PQRDAQAAREFILKMFVDLNPDSDKIIYSHFTCATDTENI 280 290 300 310 320 330 360 370 380 pF1KB3 RFVFHAVKDTILQENLKDIMLQ :::: :::::::: :::. : NP_002 RFVFAAVKDTILQLNLKEYNLV 340 350 381 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 02:46:43 2016 done: Fri Nov 4 02:46:45 2016 Total Scan time: 7.390 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]