FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3987, 381 aa
1>>>pF1KB3987 381 - 381 aa - 381 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.5509+/-0.000438; mu= 22.0371+/- 0.027
mean_var=76.3440+/-15.137, 0's: 0 Z-trim(111.8): 96 B-trim: 765 in 1/51
Lambda= 0.146787
statistics sampled from 20450 (20557) to 20450 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.601), E-opt: 0.2 (0.241), width: 16
Scan time: 7.390
The best scores are: opt bits E(85289)
NP_031379 (OMIM: 604394) guanine nucleotide-bindin ( 381) 2496 538.2 1.2e-152
XP_011513590 (OMIM: 604394) PREDICTED: guanine nuc ( 284) 1850 401.3 1.5e-111
NP_001269370 (OMIM: 604394) guanine nucleotide-bin ( 322) 1848 400.9 2.2e-111
XP_016867497 (OMIM: 604394) PREDICTED: guanine nuc ( 253) 1670 363.1 4.1e-100
NP_006563 (OMIM: 604406) guanine nucleotide-bindin ( 377) 1575 343.2 6.1e-94
NP_001269369 (OMIM: 604394) guanine nucleotide-bin ( 305) 1372 300.1 4.6e-81
NP_001280021 (OMIM: 604394) guanine nucleotide-bin ( 364) 1261 276.7 6.2e-74
NP_001269354 (OMIM: 604406) guanine nucleotide-bin ( 282) 1254 275.1 1.5e-73
NP_002063 (OMIM: 163000,185300,600998) guanine nuc ( 359) 999 221.2 3.1e-57
NP_002058 (OMIM: 139313) guanine nucleotide-bindin ( 359) 978 216.7 6.7e-56
NP_004288 (OMIM: 604397) guanine nucleotide-bindin ( 355) 948 210.4 5.5e-54
NP_066268 (OMIM: 139311,615473) guanine nucleotide ( 354) 933 207.2 4.9e-53
NP_001095856 (OMIM: 139395) guanine nucleotide-bin ( 354) 932 207.0 5.7e-53
XP_011539566 (OMIM: 139340,613856) PREDICTED: guan ( 354) 916 203.6 6e-52
NP_005263 (OMIM: 139340,613856) guanine nucleotide ( 354) 916 203.6 6e-52
NP_620073 (OMIM: 139311,615473) guanine nucleotide ( 354) 914 203.2 8e-52
NP_002060 (OMIM: 139310) guanine nucleotide-bindin ( 354) 912 202.7 1.1e-51
NP_006487 (OMIM: 139370,602483) guanine nucleotide ( 354) 902 200.6 4.7e-51
NP_002064 (OMIM: 139160) guanine nucleotide-bindin ( 355) 895 199.1 1.3e-50
NP_653082 (OMIM: 139330,610444,616389) guanine nuc ( 350) 880 196.0 1.2e-49
NP_000163 (OMIM: 139330,610444,616389) guanine nuc ( 350) 880 196.0 1.2e-49
NP_002061 (OMIM: 139360,192605) guanine nucleotide ( 355) 871 194.1 4.4e-49
XP_016870117 (OMIM: 163000,185300,600998) PREDICTE ( 301) 842 187.8 2.8e-47
NP_001159897 (OMIM: 139360,192605) guanine nucleot ( 318) 813 181.7 2e-45
NP_001269549 (OMIM: 139360,192605) guanine nucleot ( 339) 813 181.8 2.1e-45
NP_001269548 (OMIM: 139360,192605) guanine nucleot ( 339) 813 181.8 2.1e-45
XP_011521305 (OMIM: 139311,615473) PREDICTED: guan ( 312) 806 180.2 5.6e-45
NP_002059 (OMIM: 139314) guanine nucleotide-bindin ( 374) 804 179.9 8.5e-45
XP_016870830 (OMIM: 604397) PREDICTED: guanine nuc ( 301) 795 177.9 2.8e-44
NP_001243343 (OMIM: 139310) guanine nucleotide-bin ( 302) 787 176.2 9e-44
XP_011514426 (OMIM: 139395) PREDICTED: guanine nuc ( 297) 775 173.6 5.2e-43
NP_001269546 (OMIM: 139360,192605) guanine nucleot ( 303) 743 166.9 5.7e-41
XP_011517526 (OMIM: 604397) PREDICTED: guanine nuc ( 237) 735 165.1 1.6e-40
NP_001070957 (OMIM: 102200,103580,139320,166350,17 ( 379) 719 161.9 2.3e-39
NP_536351 (OMIM: 102200,103580,139320,166350,17480 ( 380) 716 161.3 3.5e-39
XP_016883303 (OMIM: 102200,103580,139320,166350,17 (1022) 720 162.6 3.8e-39
NP_001269547 (OMIM: 139360,192605) guanine nucleot ( 274) 712 160.3 5.1e-39
XP_016883302 (OMIM: 102200,103580,139320,166350,17 (1023) 717 161.9 5.9e-39
NP_892023 (OMIM: 139312,615073) guanine nucleotide ( 458) 712 160.5 7.2e-39
NP_001135811 (OMIM: 139312,615073) guanine nucleot ( 381) 681 153.9 6e-37
NP_001248372 (OMIM: 139312,615073) guanine nucleot ( 381) 681 153.9 6e-37
XP_016883304 (OMIM: 102200,103580,139320,166350,17 ( 347) 666 150.6 5.1e-36
XP_011522504 (OMIM: 604406) PREDICTED: guanine nuc ( 203) 660 149.1 8.6e-36
XP_016883306 (OMIM: 102200,103580,139320,166350,17 ( 320) 590 134.5 3.4e-31
XP_016883307 (OMIM: 102200,103580,139320,166350,17 ( 320) 590 134.5 3.4e-31
XP_016883308 (OMIM: 102200,103580,139320,166350,17 ( 320) 590 134.5 3.4e-31
XP_016884275 (OMIM: 139160) PREDICTED: guanine nuc ( 307) 576 131.5 2.6e-30
XP_016883305 (OMIM: 102200,103580,139320,166350,17 ( 320) 567 129.6 9.9e-30
XP_016883309 (OMIM: 102200,103580,139320,166350,17 ( 320) 567 129.6 9.9e-30
NP_001296790 (OMIM: 102200,103580,139320,166350,17 ( 335) 567 129.6 1e-29
>>NP_031379 (OMIM: 604394) guanine nucleotide-binding pr (381 aa)
initn: 2496 init1: 2496 opt: 2496 Z-score: 2861.6 bits: 538.2 E(85289): 1.2e-152
Smith-Waterman score: 2496; 100.0% identity (100.0% similar) in 381 aa overlap (1-381:1-381)
10 20 30 40 50 60
pF1KB3 MSGVVRTLSRCLLPAEAGGARERRAGSGARDAEREARRRSRDIDALLARERRAVRRLVKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_031 MSGVVRTLSRCLLPAEAGGARERRAGSGARDAEREARRRSRDIDALLARERRAVRRLVKI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 LLLGAGESGKSTFLKQMRIIHGREFDQKALLEFRDTIFDNILKGSRVLVDARDKLGIPWQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_031 LLLGAGESGKSTFLKQMRIIHGREFDQKALLEFRDTIFDNILKGSRVLVDARDKLGIPWQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 YSENEKHGMFLMAFENKAGLPVEPATFQLYVPALSALWRDSGIREAFSRRSEFQLGESVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_031 YSENEKHGMFLMAFENKAGLPVEPATFQLYVPALSALWRDSGIREAFSRRSEFQLGESVK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 YFLDNLDRIGQLNYFPSKQDILLARKATKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_031 YFLDNLDRIGQLNYFPSKQDILLARKATKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 CFDGITSILFMVSSSEYDQVLMEDRRTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_031 CFDGITSILFMVSSSEYDQVLMEDRRTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 LVEKVKTVSIKKHFPDFRGDPHRLEDVQRYLVQCFDRKRRNRSKPLFHHFTTAIDTENVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_031 LVEKVKTVSIKKHFPDFRGDPHRLEDVQRYLVQCFDRKRRNRSKPLFHHFTTAIDTENVR
310 320 330 340 350 360
370 380
pF1KB3 FVFHAVKDTILQENLKDIMLQ
:::::::::::::::::::::
NP_031 FVFHAVKDTILQENLKDIMLQ
370 380
>>XP_011513590 (OMIM: 604394) PREDICTED: guanine nucleot (284 aa)
initn: 1850 init1: 1850 opt: 1850 Z-score: 2123.8 bits: 401.3 E(85289): 1.5e-111
Smith-Waterman score: 1850; 98.9% identity (99.6% similar) in 281 aa overlap (101-381:4-284)
80 90 100 110 120 130
pF1KB3 STFLKQMRIIHGREFDQKALLEFRDTIFDNILKGSRVLVDARDKLGIPWQYSENEKHGMF
. .:::::::::::::::::::::::::::
XP_011 MTKVTQGSRVLVDARDKLGIPWQYSENEKHGMF
10 20 30
140 150 160 170 180 190
pF1KB3 LMAFENKAGLPVEPATFQLYVPALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LMAFENKAGLPVEPATFQLYVPALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIG
40 50 60 70 80 90
200 210 220 230 240 250
pF1KB3 QLNYFPSKQDILLARKATKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLNYFPSKQDILLARKATKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILF
100 110 120 130 140 150
260 270 280 290 300 310
pF1KB3 MVSSSEYDQVLMEDRRTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKTVSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MVSSSEYDQVLMEDRRTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKTVSI
160 170 180 190 200 210
320 330 340 350 360 370
pF1KB3 KKHFPDFRGDPHRLEDVQRYLVQCFDRKRRNRSKPLFHHFTTAIDTENVRFVFHAVKDTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKHFPDFRGDPHRLEDVQRYLVQCFDRKRRNRSKPLFHHFTTAIDTENVRFVFHAVKDTI
220 230 240 250 260 270
380
pF1KB3 LQENLKDIMLQ
:::::::::::
XP_011 LQENLKDIMLQ
280
>>NP_001269370 (OMIM: 604394) guanine nucleotide-binding (322 aa)
initn: 1848 init1: 1848 opt: 1848 Z-score: 2120.8 bits: 400.9 E(85289): 2.2e-111
Smith-Waterman score: 1848; 99.6% identity (100.0% similar) in 279 aa overlap (103-381:44-322)
80 90 100 110 120 130
pF1KB3 FLKQMRIIHGREFDQKALLEFRDTIFDNILKGSRVLVDARDKLGIPWQYSENEKHGMFLM
.:::::::::::::::::::::::::::::
NP_001 MPGSRGSGSTPDGNRKCCRFEHLLIAHPGSRGSRVLVDARDKLGIPWQYSENEKHGMFLM
20 30 40 50 60 70
140 150 160 170 180 190
pF1KB3 AFENKAGLPVEPATFQLYVPALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AFENKAGLPVEPATFQLYVPALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQL
80 90 100 110 120 130
200 210 220 230 240 250
pF1KB3 NYFPSKQDILLARKATKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NYFPSKQDILLARKATKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMV
140 150 160 170 180 190
260 270 280 290 300 310
pF1KB3 SSSEYDQVLMEDRRTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKTVSIKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSSEYDQVLMEDRRTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKTVSIKK
200 210 220 230 240 250
320 330 340 350 360 370
pF1KB3 HFPDFRGDPHRLEDVQRYLVQCFDRKRRNRSKPLFHHFTTAIDTENVRFVFHAVKDTILQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HFPDFRGDPHRLEDVQRYLVQCFDRKRRNRSKPLFHHFTTAIDTENVRFVFHAVKDTILQ
260 270 280 290 300 310
380
pF1KB3 ENLKDIMLQ
:::::::::
NP_001 ENLKDIMLQ
320
>>XP_016867497 (OMIM: 604394) PREDICTED: guanine nucleot (253 aa)
initn: 1670 init1: 1670 opt: 1670 Z-score: 1918.4 bits: 363.1 E(85289): 4.1e-100
Smith-Waterman score: 1670; 100.0% identity (100.0% similar) in 253 aa overlap (129-381:1-253)
100 110 120 130 140 150
pF1KB3 DNILKGSRVLVDARDKLGIPWQYSENEKHGMFLMAFENKAGLPVEPATFQLYVPALSALW
::::::::::::::::::::::::::::::
XP_016 MFLMAFENKAGLPVEPATFQLYVPALSALW
10 20 30
160 170 180 190 200 210
pF1KB3 RDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQLNYFPSKQDILLARKATKGIVEHDFVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQLNYFPSKQDILLARKATKGIVEHDFVI
40 50 60 70 80 90
220 230 240 250 260 270
pF1KB3 KKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLMEDRRTNRLVESMNIFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLMEDRRTNRLVESMNIFE
100 110 120 130 140 150
280 290 300 310 320 330
pF1KB3 TIVNNKLFFNVSIILFLNKMDLLVEKVKTVSIKKHFPDFRGDPHRLEDVQRYLVQCFDRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TIVNNKLFFNVSIILFLNKMDLLVEKVKTVSIKKHFPDFRGDPHRLEDVQRYLVQCFDRK
160 170 180 190 200 210
340 350 360 370 380
pF1KB3 RRNRSKPLFHHFTTAIDTENVRFVFHAVKDTILQENLKDIMLQ
:::::::::::::::::::::::::::::::::::::::::::
XP_016 RRNRSKPLFHHFTTAIDTENVRFVFHAVKDTILQENLKDIMLQ
220 230 240 250
>>NP_006563 (OMIM: 604406) guanine nucleotide-binding pr (377 aa)
initn: 1403 init1: 966 opt: 1575 Z-score: 1807.5 bits: 343.2 E(85289): 6.1e-94
Smith-Waterman score: 1575; 66.7% identity (87.3% similar) in 354 aa overlap (33-381:24-377)
10 20 30 40 50 60
pF1KB3 GVVRTLSRCLLPAEAGGARERRAGSGARDAEREARRRSRDIDALLARERRAVRRLVKILL
: : .:.:..:: :.::. :.:::::::
NP_006 MADFLPSRSVLSVCFPGCLLTSGEAEQQRKSKEIDKCLSREKTYVKRLVKILL
10 20 30 40 50
70 80 90 100 110 120
pF1KB3 LGAGESGKSTFLKQMRIIHGREFDQKALLEFRDTIFDNILKGSRVLVDARDKLGIPWQYS
::::::::::::::::::::..:::.: ::: ::..:..:: :::::::.:: ::: .
NP_006 LGAGESGKSTFLKQMRIIHGQDFDQRAREEFRPTIYSNVIKGMRVLVDAREKLHIPWGDN
60 70 80 90 100 110
130 140 150 160 170
pF1KB3 ENEKHGMFLMAFENKAGLP----VEPATFQLYVPALSALWRDSGIREAFSRRSEFQLGES
:..:: .:.:...: . :: .: :.::. ::: ::::..:..:: :::::::
NP_006 SNQQHGDKMMSFDTRAPMAAQGMVETRVFLQYLPAIRALWADSGIQNAYDRRREFQLGES
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB3 VKYFLDNLDRIGQLNYFPSKQDILLARKATKGIVEHDFVIKKIPFKMVDVGGQRSQRQKW
:::::::::..:. .:.::.:::::::. :::: :.:: ::..::::::::::::.:..:
NP_006 VKYFLDNLDKLGEPDYIPSQQDILLARRPTKGIHEYDFEIKNVPFKMVDVGGQRSERKRW
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB3 FQCFDGITSILFMVSSSEYDQVLMEDRRTNRLVESMNIFETIVNNKLFFNVSIILFLNKM
:.:::..:::::.:::::.:::::::: ::::.::.:::::::::..: ::::::::::
NP_006 FECFDSVTSILFLVSSSEFDQVLMEDRLTNRLTESLNIFETIVNNRVFSNVSIILFLNKT
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB3 DLLVEKVKTVSIKKHFPDFRGDPHRLEDVQRYLVQCFDRKRRNRS-KPLFHHFTTAIDTE
::: :::. :::: .: .:.:::: :.:::..::.:: :::... :::.:::::::.::
NP_006 DLLEEKVQIVSIKDYFLEFEGDPHCLRDVQKFLVECFRNKRRDQQQKPLYHHFTTAINTE
300 310 320 330 340 350
360 370 380
pF1KB3 NVRFVFHAVKDTILQENLKDIMLQ
:.:.::. ::::::..:::..:::
NP_006 NIRLVFRDVKDTILHDNLKQLMLQ
360 370
>>NP_001269369 (OMIM: 604394) guanine nucleotide-binding (305 aa)
initn: 1360 init1: 1360 opt: 1372 Z-score: 1576.3 bits: 300.1 E(85289): 4.6e-81
Smith-Waterman score: 1372; 84.8% identity (89.8% similar) in 256 aa overlap (127-381:54-305)
100 110 120 130 140 150
pF1KB3 IFDNILKGSRVLVDARDKLGIPWQYSENEKHGM-FLMAFENKAGLPVEPATFQLYVPALS
:: : .:. . ... . : : :
NP_001 GWEAALSAPPPFCTAWVERTGLVHFLREGGHGACFPLALLHPGSVVSFQMIYPLIVLPLC
30 40 50 60 70 80
160 170 180 190 200 210
pF1KB3 ALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQLNYFPSKQDILLARKATKGIVEHD
: :. . ::... . ::::::::::::::::::::::::::::::::::::::::
NP_001 ASWHWGLIRKGIV----LFWGESVKYFLDNLDRIGQLNYFPSKQDILLARKATKGIVEHD
90 100 110 120 130
220 230 240 250 260 270
pF1KB3 FVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLMEDRRTNRLVESMN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLMEDRRTNRLVESMN
140 150 160 170 180 190
280 290 300 310 320 330
pF1KB3 IFETIVNNKLFFNVSIILFLNKMDLLVEKVKTVSIKKHFPDFRGDPHRLEDVQRYLVQCF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IFETIVNNKLFFNVSIILFLNKMDLLVEKVKTVSIKKHFPDFRGDPHRLEDVQRYLVQCF
200 210 220 230 240 250
340 350 360 370 380
pF1KB3 DRKRRNRSKPLFHHFTTAIDTENVRFVFHAVKDTILQENLKDIMLQ
::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DRKRRNRSKPLFHHFTTAIDTENVRFVFHAVKDTILQENLKDIMLQ
260 270 280 290 300
>>NP_001280021 (OMIM: 604394) guanine nucleotide-binding (364 aa)
initn: 1261 init1: 1261 opt: 1261 Z-score: 1448.4 bits: 276.7 E(85289): 6.2e-74
Smith-Waterman score: 2341; 95.5% identity (95.5% similar) in 381 aa overlap (1-381:1-364)
10 20 30 40 50 60
pF1KB3 MSGVVRTLSRCLLPAEAGGARERRAGSGARDAEREARRRSRDIDALLARERRAVRRLVKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSGVVRTLSRCLLPAEAGGARERRAGSGARDAEREARRRSRDIDALLARERRAVRRLVKI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 LLLGAGESGKSTFLKQMRIIHGREFDQKALLEFRDTIFDNILKGSRVLVDARDKLGIPWQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLLGAGESGKSTFLKQMRIIHGREFDQKALLEFRDTIFDNILKGSRVLVDARDKLGIPWQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 YSENEKHGMFLMAFENKAGLPVEPATFQLYVPALSALWRDSGIREAFSRRSEFQLGESVK
:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YSENEKHGMFLMAFENKAGLPVEPATFQLYVPALSALWRDSGIREAFSRRSEF-------
130 140 150 160 170
190 200 210 220 230 240
pF1KB3 YFLDNLDRIGQLNYFPSKQDILLARKATKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQ
::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ----------QLNYFPSKQDILLARKATKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQ
180 190 200 210 220
250 260 270 280 290 300
pF1KB3 CFDGITSILFMVSSSEYDQVLMEDRRTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CFDGITSILFMVSSSEYDQVLMEDRRTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDL
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB3 LVEKVKTVSIKKHFPDFRGDPHRLEDVQRYLVQCFDRKRRNRSKPLFHHFTTAIDTENVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVEKVKTVSIKKHFPDFRGDPHRLEDVQRYLVQCFDRKRRNRSKPLFHHFTTAIDTENVR
290 300 310 320 330 340
370 380
pF1KB3 FVFHAVKDTILQENLKDIMLQ
:::::::::::::::::::::
NP_001 FVFHAVKDTILQENLKDIMLQ
350 360
>>NP_001269354 (OMIM: 604406) guanine nucleotide-binding (282 aa)
initn: 1082 init1: 966 opt: 1254 Z-score: 1441.7 bits: 275.1 E(85289): 1.5e-73
Smith-Waterman score: 1254; 66.5% identity (87.5% similar) in 281 aa overlap (106-381:2-282)
80 90 100 110 120 130
pF1KB3 QMRIIHGREFDQKALLEFRDTIFDNILKGSRVLVDARDKLGIPWQYSENEKHGMFLMAFE
:::::::.:: ::: . :..:: .:.:.
NP_001 MRVLVDAREKLHIPWGDNSNQQHGDKMMSFD
10 20 30
140 150 160 170 180 190
pF1KB3 NKAGLP----VEPATFQLYVPALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQ
..: . :: .: :.::. ::: ::::..:..:: ::::::::::::::::..:.
NP_001 TRAPMAAQGMVETRVFLQYLPAIRALWADSGIQNAYDRRREFQLGESVKYFLDNLDKLGE
40 50 60 70 80 90
200 210 220 230 240 250
pF1KB3 LNYFPSKQDILLARKATKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFM
.:.::.:::::::. :::: :.:: ::..::::::::::::.:..::.:::..:::::.
NP_001 PDYIPSQQDILLARRPTKGIHEYDFEIKNVPFKMVDVGGQRSERKRWFECFDSVTSILFL
100 110 120 130 140 150
260 270 280 290 300 310
pF1KB3 VSSSEYDQVLMEDRRTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKTVSIK
:::::.:::::::: ::::.::.:::::::::..: :::::::::: ::: :::. ::::
NP_001 VSSSEFDQVLMEDRLTNRLTESLNIFETIVNNRVFSNVSIILFLNKTDLLEEKVQIVSIK
160 170 180 190 200 210
320 330 340 350 360 370
pF1KB3 KHFPDFRGDPHRLEDVQRYLVQCFDRKRRNRS-KPLFHHFTTAIDTENVRFVFHAVKDTI
.: .:.:::: :.:::..::.:: :::... :::.:::::::.:::.:.::. :::::
NP_001 DYFLEFEGDPHCLRDVQKFLVECFRNKRRDQQQKPLYHHFTTAINTENIRLVFRDVKDTI
220 230 240 250 260 270
380
pF1KB3 LQENLKDIMLQ
:..:::..:::
NP_001 LHDNLKQLMLQ
280
>>NP_002063 (OMIM: 163000,185300,600998) guanine nucleot (359 aa)
initn: 1012 init1: 750 opt: 999 Z-score: 1148.6 bits: 221.2 E(85289): 3.1e-57
Smith-Waterman score: 999; 45.0% identity (73.9% similar) in 349 aa overlap (34-380:16-358)
10 20 30 40 50 60
pF1KB3 VVRTLSRCLLPAEAGGARERRAGSGARDAEREARRRSRDIDALLARERRAVRRLVKILLL
.:::: . .:. : :..: .:: .:.:::
NP_002 MTLESIMACCLSEEAKEARRINDEIERQLRRDKRDARRELKLLLL
10 20 30 40
70 80 90 100 110 120
pF1KB3 GAGESGKSTFLKQMRIIHGREFDQKALLEFRDTIFDNILKGSRVLVDARDKLGIPWQYSE
:.::::::::.:::::::: .... : ...::. . .... : : : ::..: .
NP_002 GTGESGKSTFIKQMRIIHGSGYSDEDKRGFTKLVYQNIFTAMQAMIRAMDTLKIPYKYEH
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB3 NEKHGMFLMAFE-NKAGLPVEPATFQLYVPALSALWRDSGIREAFSRRSEFQLGESVKYF
:. :.... . .:.. .: :: :...:: : ::.: ..:: :.::..:.::.
NP_002 NKAHAQLVREVDVEKVSAFENP-----YVDAIKSLWNDPGIQECYDRRREYQLSDSTKYY
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB3 LDNLDRIGQLNYFPSKQDILLARKATKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQCF
:..:::... :.:..::.: .: : ::.:. : .... :.:::::::::.:.::..::
NP_002 LNDLDRVADPAYLPTQQDVLRVRVPTTGIIEYPFDLQSVIFRMVDVGGQRSERRKWIHCF
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB3 DGITSILFMVSSSEYDQVLMEDRRTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDLLV
...:::.:.:. :::::::.:. ::. :: .:.::.. : : :.:::::: :::
NP_002 ENVTSIMFLVALSEYDQVLVESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLE
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB3 EKVKTVSIKKHFPDFRGDPHRLEDVQR-YLVQCFDRKRRNRSKPLFHHFTTAIDTENVRF
::. . .::.. : :.: .. : .... : . .: .. ::: : ::::.::
NP_002 EKIMYSHLVDYFPEYDG-PQRDAQAAREFILKMFVDLNPDSDKIIYSHFTCATDTENIRF
290 300 310 320 330
370 380
pF1KB3 VFHAVKDTILQENLKDIMLQ
:: :::::::: :::. :
NP_002 VFAAVKDTILQLNLKEYNLV
340 350
>>NP_002058 (OMIM: 139313) guanine nucleotide-binding pr (359 aa)
initn: 944 init1: 752 opt: 978 Z-score: 1124.5 bits: 216.7 E(85289): 6.7e-56
Smith-Waterman score: 978; 43.9% identity (72.9% similar) in 351 aa overlap (31-380:13-358)
10 20 30 40 50 60
pF1KB3 MSGVVRTLSRCLLPAEAGGARERRAGSGARDAEREARRRSRDIDALLARERRAVRRLVKI
: .:..: . .:. : :..: .:: .:.
NP_002 MTLESMMACCLSDEVKESKRINAEIEKQLRRDKRDARRELKL
10 20 30 40
70 80 90 100 110 120
pF1KB3 LLLGAGESGKSTFLKQMRIIHGREFDQKALLEFRDTIFDNILKGSRVLVDARDKLGIPWQ
::::.::::::::.:::::::: .... : ...::. . .... : . : : ..
NP_002 LLLGTGESGKSTFIKQMRIIHGAGYSEEDKRGFTKLVYQNIFTAMQAMIRAMETLKILYK
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB3 YSENEKHGMFLMAFENKAGLPVEPATFQLYVPALSALWRDSGIREAFSRRSEFQLGESVK
: .:. ..... . . : . :: :...::.: ::.: ..:: :.::..:.:
NP_002 YEQNKANALLIREVDVEKVTTFE----HQYVSAIKTLWEDPGIQECYDRRREYQLSDSAK
110 120 130 140 150
190 200 210 220 230 240
pF1KB3 YFLDNLDRIGQLNYFPSKQDILLARKATKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQ
:.: ..:::. :.:.:..::.: .: : ::.:. : ...: :.:::::::::.:.::..
NP_002 YYLTDVDRIATLGYLPTQQDVLRVRVPTTGIIEYPFDLENIIFRMVDVGGQRSERRKWIH
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB3 CFDGITSILFMVSSSEYDQVLMEDRRTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDL
::...:::.:.:. :::::::.:. ::. :: .:.::.. : : :.:::::: ::
NP_002 CFENVTSIMFLVALSEYDQVLVESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDL
220 230 240 250 260 270
310 320 330 340 350
pF1KB3 LVEKVKTVSIKKHFPDFRGDPHRLEDVQR-YLVQCFDRKRRNRSKPLFHHFTTAIDTENV
: .:. . .::.: : :.: .. : .... : . .: .. ::: : ::::.
NP_002 LEDKILYSHLVDYFPEFDG-PQRDAQAAREFILKMFVDLNPDSDKIIYSHFTCATDTENI
280 290 300 310 320 330
360 370 380
pF1KB3 RFVFHAVKDTILQENLKDIMLQ
:::: :::::::: :::. :
NP_002 RFVFAAVKDTILQLNLKEYNLV
340 350
381 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 02:46:43 2016 done: Fri Nov 4 02:46:45 2016
Total Scan time: 7.390 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]