FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3988, 173 aa
1>>>pF1KB3988 173 - 173 aa - 173 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.5843+/-0.000371; mu= 10.3037+/- 0.023
mean_var=84.9976+/-17.434, 0's: 0 Z-trim(115.1): 251 B-trim: 283 in 1/49
Lambda= 0.139114
statistics sampled from 24943 (25281) to 24943 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.685), E-opt: 0.2 (0.296), width: 16
Scan time: 5.390
The best scores are: opt bits E(85289)
NP_003454 (OMIM: 601585) protein tyrosine phosphat ( 173) 1181 246.6 1.5e-65
XP_016866760 (OMIM: 601585) PREDICTED: protein tyr ( 173) 1181 246.6 1.5e-65
XP_011534414 (OMIM: 601585) PREDICTED: protein tyr ( 173) 1181 246.6 1.5e-65
XP_016866759 (OMIM: 601585) PREDICTED: protein tyr ( 173) 1181 246.6 1.5e-65
XP_011534413 (OMIM: 601585) PREDICTED: protein tyr ( 173) 1181 246.6 1.5e-65
NP_536316 (OMIM: 601584) protein tyrosine phosphat ( 167) 1044 219.1 2.7e-57
XP_011515107 (OMIM: 606449) PREDICTED: protein tyr ( 173) 962 202.7 2.5e-52
NP_116000 (OMIM: 606449) protein tyrosine phosphat ( 173) 962 202.7 2.5e-52
XP_005250821 (OMIM: 606449) PREDICTED: protein tyr ( 173) 962 202.7 2.5e-52
XP_011515105 (OMIM: 606449) PREDICTED: protein tyr ( 173) 962 202.7 2.5e-52
XP_016866761 (OMIM: 601585) PREDICTED: protein tyr ( 135) 912 192.6 2.1e-49
XP_006716563 (OMIM: 606449) PREDICTED: protein tyr ( 149) 764 162.9 2e-40
XP_005271289 (OMIM: 601584) PREDICTED: protein tyr ( 136) 683 146.6 1.5e-35
NP_001182030 (OMIM: 601584) protein tyrosine phosp ( 136) 683 146.6 1.5e-35
XP_016857890 (OMIM: 601584) PREDICTED: protein tyr ( 136) 683 146.6 1.5e-35
XP_005271288 (OMIM: 601584) PREDICTED: protein tyr ( 142) 674 144.8 5.3e-35
NP_001182029 (OMIM: 601584) protein tyrosine phosp ( 142) 674 144.8 5.3e-35
XP_016868487 (OMIM: 606449) PREDICTED: protein tyr ( 148) 616 133.2 1.8e-31
NP_009010 (OMIM: 606449) protein tyrosine phosphat ( 148) 616 133.2 1.8e-31
XP_016868488 (OMIM: 606449) PREDICTED: protein tyr ( 124) 418 93.4 1.4e-19
XP_016870738 (OMIM: 603505) PREDICTED: dual specif ( 296) 188 47.5 2.2e-05
XP_011517461 (OMIM: 603505) PREDICTED: dual specif ( 331) 188 47.6 2.4e-05
XP_016870737 (OMIM: 603505) PREDICTED: dual specif ( 390) 188 47.6 2.7e-05
XP_016870736 (OMIM: 603505) PREDICTED: dual specif ( 422) 188 47.6 2.9e-05
XP_016870735 (OMIM: 603505) PREDICTED: dual specif ( 448) 188 47.7 3e-05
XP_005252345 (OMIM: 603505) PREDICTED: dual specif ( 448) 188 47.7 3e-05
NP_003662 (OMIM: 603505) dual specificity protein ( 459) 188 47.7 3e-05
NP_001070649 (OMIM: 603505) dual specificity prote ( 461) 188 47.7 3.1e-05
XP_011517460 (OMIM: 603505) PREDICTED: dual specif ( 471) 188 47.7 3.1e-05
XP_016870734 (OMIM: 603505) PREDICTED: dual specif ( 479) 188 47.7 3.2e-05
XP_016870733 (OMIM: 603505) PREDICTED: dual specif ( 483) 188 47.7 3.2e-05
XP_016870732 (OMIM: 603505) PREDICTED: dual specif ( 485) 188 47.7 3.2e-05
NP_201588 (OMIM: 603505) dual specificity protein ( 498) 188 47.7 3.2e-05
XP_011517458 (OMIM: 603505) PREDICTED: dual specif ( 514) 188 47.7 3.3e-05
XP_016870731 (OMIM: 603505) PREDICTED: dual specif ( 520) 188 47.7 3.4e-05
XP_016870730 (OMIM: 603505) PREDICTED: dual specif ( 544) 188 47.7 3.5e-05
XP_011517455 (OMIM: 603505) PREDICTED: dual specif ( 552) 188 47.7 3.5e-05
XP_011517454 (OMIM: 603505) PREDICTED: dual specif ( 564) 188 47.7 3.6e-05
XP_011517453 (OMIM: 603505) PREDICTED: dual specif ( 578) 188 47.7 3.6e-05
XP_011517452 (OMIM: 603505) PREDICTED: dual specif ( 578) 188 47.7 3.6e-05
XP_011517451 (OMIM: 603505) PREDICTED: dual specif ( 585) 188 47.7 3.7e-05
XP_011517450 (OMIM: 603505) PREDICTED: dual specif ( 591) 188 47.7 3.7e-05
XP_011517449 (OMIM: 603505) PREDICTED: dual specif ( 603) 188 47.7 3.8e-05
XP_016870729 (OMIM: 603505) PREDICTED: dual specif ( 613) 188 47.8 3.8e-05
NP_201570 (OMIM: 603504,616958) dual specificity p ( 383) 179 45.8 9.3e-05
XP_011540648 (OMIM: 603504,616958) PREDICTED: dual ( 392) 179 45.8 9.4e-05
XP_016858136 (OMIM: 603504,616958) PREDICTED: dual ( 489) 179 45.9 0.00011
XP_016858135 (OMIM: 603504,616958) PREDICTED: dual ( 490) 179 45.9 0.00011
XP_011540647 (OMIM: 603504,616958) PREDICTED: dual ( 495) 179 45.9 0.00011
NP_001306140 (OMIM: 603504,616958) dual specificit ( 565) 179 45.9 0.00013
>>NP_003454 (OMIM: 601585) protein tyrosine phosphatase (173 aa)
initn: 1181 init1: 1181 opt: 1181 Z-score: 1298.1 bits: 246.6 E(85289): 1.5e-65
Smith-Waterman score: 1181; 100.0% identity (100.0% similar) in 173 aa overlap (1-173:1-173)
10 20 30 40 50 60
pF1KB3 MARMNRPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MARMNRPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 EGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 EGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALI
70 80 90 100 110 120
130 140 150 160 170
pF1KB3 EGGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNNCCIQ
:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 EGGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNNCCIQ
130 140 150 160 170
>>XP_016866760 (OMIM: 601585) PREDICTED: protein tyrosin (173 aa)
initn: 1181 init1: 1181 opt: 1181 Z-score: 1298.1 bits: 246.6 E(85289): 1.5e-65
Smith-Waterman score: 1181; 100.0% identity (100.0% similar) in 173 aa overlap (1-173:1-173)
10 20 30 40 50 60
pF1KB3 MARMNRPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MARMNRPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 EGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALI
70 80 90 100 110 120
130 140 150 160 170
pF1KB3 EGGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNNCCIQ
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNNCCIQ
130 140 150 160 170
>>XP_011534414 (OMIM: 601585) PREDICTED: protein tyrosin (173 aa)
initn: 1181 init1: 1181 opt: 1181 Z-score: 1298.1 bits: 246.6 E(85289): 1.5e-65
Smith-Waterman score: 1181; 100.0% identity (100.0% similar) in 173 aa overlap (1-173:1-173)
10 20 30 40 50 60
pF1KB3 MARMNRPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MARMNRPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 EGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALI
70 80 90 100 110 120
130 140 150 160 170
pF1KB3 EGGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNNCCIQ
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNNCCIQ
130 140 150 160 170
>>XP_016866759 (OMIM: 601585) PREDICTED: protein tyrosin (173 aa)
initn: 1181 init1: 1181 opt: 1181 Z-score: 1298.1 bits: 246.6 E(85289): 1.5e-65
Smith-Waterman score: 1181; 100.0% identity (100.0% similar) in 173 aa overlap (1-173:1-173)
10 20 30 40 50 60
pF1KB3 MARMNRPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MARMNRPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 EGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALI
70 80 90 100 110 120
130 140 150 160 170
pF1KB3 EGGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNNCCIQ
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNNCCIQ
130 140 150 160 170
>>XP_011534413 (OMIM: 601585) PREDICTED: protein tyrosin (173 aa)
initn: 1181 init1: 1181 opt: 1181 Z-score: 1298.1 bits: 246.6 E(85289): 1.5e-65
Smith-Waterman score: 1181; 100.0% identity (100.0% similar) in 173 aa overlap (1-173:1-173)
10 20 30 40 50 60
pF1KB3 MARMNRPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MARMNRPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 EGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALI
70 80 90 100 110 120
130 140 150 160 170
pF1KB3 EGGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNNCCIQ
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNNCCIQ
130 140 150 160 170
>>NP_536316 (OMIM: 601584) protein tyrosine phosphatase (167 aa)
initn: 1046 init1: 1023 opt: 1044 Z-score: 1149.7 bits: 219.1 E(85289): 2.7e-57
Smith-Waterman score: 1044; 87.6% identity (94.7% similar) in 170 aa overlap (4-173:1-167)
10 20 30 40 50 60
pF1KB3 MARMNRPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEK
::::::::..:.:::::::::::::::::: ::::::::::.::::.:::: . :::
NP_536 MNRPAPVEISYENMRFLITHNPTNATLNKFTEELKKYGVTTLVRVCDATYDKAPVEK
10 20 30 40 50
70 80 90 100 110 120
pF1KB3 EGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALI
:::::::::::::::: ::::::::.:.: :::::::::.::::::::::::::::::::
NP_536 EGIHVLDWPFDDGAPPPNQIVDDWLNLLKTKFREEPGCCVAVHCVAGLGRAPVLVALALI
60 70 80 90 100 110
130 140 150 160 170
pF1KB3 EGGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNNCCIQ
: ::::::::::::::::::::::::::::::::::::::.:.::: ::.:
NP_536 ECGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFRDTNGH---CCVQ
120 130 140 150 160
>>XP_011515107 (OMIM: 606449) PREDICTED: protein tyrosin (173 aa)
initn: 962 init1: 962 opt: 962 Z-score: 1060.5 bits: 202.7 E(85289): 2.5e-52
Smith-Waterman score: 962; 79.1% identity (92.4% similar) in 172 aa overlap (1-172:1-172)
10 20 30 40 50 60
pF1KB3 MARMNRPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEK
::::::::::::.::.::::::::::::::. :::.:::::.::.:::::.::: : .::
XP_011 MARMNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 EGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALI
.:: :.:::::::::: ...:.::::::: :: : :: :.::::::::::::::::::::
XP_011 DGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI
70 80 90 100 110 120
130 140 150 160 170
pF1KB3 EGGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNNCCIQ
:.:::::::.::::::::::.::::: ::::::::.:::::: . :.. ::.
XP_011 ESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCVM
130 140 150 160 170
>>NP_116000 (OMIM: 606449) protein tyrosine phosphatase (173 aa)
initn: 962 init1: 962 opt: 962 Z-score: 1060.5 bits: 202.7 E(85289): 2.5e-52
Smith-Waterman score: 962; 79.1% identity (92.4% similar) in 172 aa overlap (1-172:1-172)
10 20 30 40 50 60
pF1KB3 MARMNRPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEK
::::::::::::.::.::::::::::::::. :::.:::::.::.:::::.::: : .::
NP_116 MARMNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 EGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALI
.:: :.:::::::::: ...:.::::::: :: : :: :.::::::::::::::::::::
NP_116 DGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI
70 80 90 100 110 120
130 140 150 160 170
pF1KB3 EGGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNNCCIQ
:.:::::::.::::::::::.::::: ::::::::.:::::: . :.. ::.
NP_116 ESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCVM
130 140 150 160 170
>>XP_005250821 (OMIM: 606449) PREDICTED: protein tyrosin (173 aa)
initn: 962 init1: 962 opt: 962 Z-score: 1060.5 bits: 202.7 E(85289): 2.5e-52
Smith-Waterman score: 962; 79.1% identity (92.4% similar) in 172 aa overlap (1-172:1-172)
10 20 30 40 50 60
pF1KB3 MARMNRPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEK
::::::::::::.::.::::::::::::::. :::.:::::.::.:::::.::: : .::
XP_005 MARMNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 EGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALI
.:: :.:::::::::: ...:.::::::: :: : :: :.::::::::::::::::::::
XP_005 DGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI
70 80 90 100 110 120
130 140 150 160 170
pF1KB3 EGGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNNCCIQ
:.:::::::.::::::::::.::::: ::::::::.:::::: . :.. ::.
XP_005 ESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCVM
130 140 150 160 170
>>XP_011515105 (OMIM: 606449) PREDICTED: protein tyrosin (173 aa)
initn: 962 init1: 962 opt: 962 Z-score: 1060.5 bits: 202.7 E(85289): 2.5e-52
Smith-Waterman score: 962; 79.1% identity (92.4% similar) in 172 aa overlap (1-172:1-172)
10 20 30 40 50 60
pF1KB3 MARMNRPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEK
::::::::::::.::.::::::::::::::. :::.:::::.::.:::::.::: : .::
XP_011 MARMNRPAPVEVSYKHMRFLITHNPTNATLSTFIEDLKKYGATTVVRVCEVTYDKTPLEK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 EGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALI
.:: :.:::::::::: ...:.::::::: :: : :: :.::::::::::::::::::::
XP_011 DGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPGSCVAVHCVAGLGRAPVLVALALI
70 80 90 100 110 120
130 140 150 160 170
pF1KB3 EGGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNNCCIQ
:.:::::::.::::::::::.::::: ::::::::.:::::: . :.. ::.
XP_011 ESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHTHKTRCCVM
130 140 150 160 170
173 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 21:20:15 2016 done: Thu Nov 3 21:20:16 2016
Total Scan time: 5.390 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]