FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4011, 551 aa 1>>>pF1KB4011 551 - 551 aa - 551 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.3778+/-0.000378; mu= 13.8078+/- 0.023 mean_var=97.5053+/-19.601, 0's: 0 Z-trim(114.8): 31 B-trim: 0 in 0/54 Lambda= 0.129885 statistics sampled from 24834 (24862) to 24834 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.664), E-opt: 0.2 (0.292), width: 16 Scan time: 9.850 The best scores are: opt bits E(85289) XP_016883979 (OMIM: 236200,613381) PREDICTED: cyst ( 551) 3684 701.0 2.4e-201 NP_001171480 (OMIM: 236200,613381) cystathionine b ( 551) 3684 701.0 2.4e-201 NP_001307227 (OMIM: 236200,613381) cystathionine b ( 551) 3684 701.0 2.4e-201 NP_001171479 (OMIM: 236200,613381) cystathionine b ( 551) 3684 701.0 2.4e-201 NP_000062 (OMIM: 236200,613381) cystathionine beta ( 551) 3684 701.0 2.4e-201 XP_016883981 (OMIM: 236200,613381) PREDICTED: cyst ( 551) 3684 701.0 2.4e-201 XP_016883980 (OMIM: 236200,613381) PREDICTED: cyst ( 551) 3684 701.0 2.4e-201 XP_016883978 (OMIM: 236200,613381) PREDICTED: cyst ( 565) 3473 661.5 2e-189 XP_011528079 (OMIM: 236200,613381) PREDICTED: cyst ( 565) 3473 661.5 2e-189 XP_011528084 (OMIM: 236200,613381) PREDICTED: cyst ( 565) 3473 661.5 2e-189 XP_011528083 (OMIM: 236200,613381) PREDICTED: cyst ( 565) 3473 661.5 2e-189 XP_011528078 (OMIM: 236200,613381) PREDICTED: cyst ( 568) 2941 561.8 2e-159 XP_011528077 (OMIM: 236200,613381) PREDICTED: cyst ( 568) 2941 561.8 2e-159 NP_001308001 (OMIM: 236200,613381) cystathionine b ( 446) 2931 559.9 6.1e-159 XP_016883982 (OMIM: 236200,613381) PREDICTED: cyst ( 496) 2730 522.2 1.5e-147 XP_011528076 (OMIM: 236200,613381) PREDICTED: cyst ( 582) 2730 522.3 1.7e-147 XP_011528075 (OMIM: 236200,613381) PREDICTED: cyst ( 582) 2730 522.3 1.7e-147 XP_011528085 (OMIM: 236200,613381) PREDICTED: cyst ( 460) 2720 520.3 5e-147 XP_006721628 (OMIM: 606477) PREDICTED: serine race ( 340) 254 58.2 4.9e-08 NP_068766 (OMIM: 606477) serine racemase isoform a ( 340) 254 58.2 4.9e-08 XP_011522276 (OMIM: 606477) PREDICTED: serine race ( 340) 254 58.2 4.9e-08 XP_006721629 (OMIM: 606477) PREDICTED: serine race ( 340) 254 58.2 4.9e-08 >>XP_016883979 (OMIM: 236200,613381) PREDICTED: cystathi (551 aa) initn: 3684 init1: 3684 opt: 3684 Z-score: 3735.7 bits: 701.0 E(85289): 2.4e-201 Smith-Waterman score: 3684; 100.0% identity (100.0% similar) in 551 aa overlap (1-551:1-551) 10 20 30 40 50 60 pF1KB4 MPSETPQAEVGPTGCPHRSGPHSAKGSLEKGSPEDKEAKEPLWIRPDAPSRCTWQLGRPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MPSETPQAEVGPTGCPHRSGPHSAKGSLEKGSPEDKEAKEPLWIRPDAPSRCTWQLGRPA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 SESPHHHTAPAKSPKILPDILKKIGDTPMVRINKIGKKFGLKCELLAKCEFFNAGGSVKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SESPHHHTAPAKSPKILPDILKKIGDTPMVRINKIGKKFGLKCELLAKCEFFNAGGSVKD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 RISLRMIEDAERDGTLKPGDTIIEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RISLRMIEDAERDGTLKPGDTIIEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 LRALGAEIVRTPTNARFDSPESHVGVAWRLKNEIPNSHILDQYRNASNPLAHYDTTADEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LRALGAEIVRTPTNARFDSPESHVGVAWRLKNEIPNSHILDQYRNASNPLAHYDTTADEI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 LQQCDGKLDMLVASVGTGGTITGIARKLKEKCPGCRIIGVDPEGSILAEPEELNQTEQTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQQCDGKLDMLVASVGTGGTITGIARKLKEKCPGCRIIGVDPEGSILAEPEELNQTEQTT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 YEVEGIGYDFIPTVLDRTVVDKWFKSNDEEAFTFARMLIAQEGLLCGGSAGSTVAVAVKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YEVEGIGYDFIPTVLDRTVVDKWFKSNDEEAFTFARMLIAQEGLLCGGSAGSTVAVAVKA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 AQELQEGQRCVVILPDSVRNYMTKFLSDRWMLQKGFLKEEDLTEKKPWWWHLRVQELGLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AQELQEGQRCVVILPDSVRNYMTKFLSDRWMLQKGFLKEEDLTEKKPWWWHLRVQELGLS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB4 APLTVLPTITCGHTIEILREKGFDQAPVVDEAGVILGMVTLGNMLSSLLAGKVQPSDQVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 APLTVLPTITCGHTIEILREKGFDQAPVVDEAGVILGMVTLGNMLSSLLAGKVQPSDQVG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB4 KVIYKQFKQIRLTDTLGRLSHILEMDHFALVVHEQIQYHSTGKSSQRQMVFGVVTAIDLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KVIYKQFKQIRLTDTLGRLSHILEMDHFALVVHEQIQYHSTGKSSQRQMVFGVVTAIDLL 490 500 510 520 530 540 550 pF1KB4 NFVAAQERDQK ::::::::::: XP_016 NFVAAQERDQK 550 >>NP_001171480 (OMIM: 236200,613381) cystathionine beta- (551 aa) initn: 3684 init1: 3684 opt: 3684 Z-score: 3735.7 bits: 701.0 E(85289): 2.4e-201 Smith-Waterman score: 3684; 100.0% identity (100.0% similar) in 551 aa overlap (1-551:1-551) 10 20 30 40 50 60 pF1KB4 MPSETPQAEVGPTGCPHRSGPHSAKGSLEKGSPEDKEAKEPLWIRPDAPSRCTWQLGRPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MPSETPQAEVGPTGCPHRSGPHSAKGSLEKGSPEDKEAKEPLWIRPDAPSRCTWQLGRPA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 SESPHHHTAPAKSPKILPDILKKIGDTPMVRINKIGKKFGLKCELLAKCEFFNAGGSVKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SESPHHHTAPAKSPKILPDILKKIGDTPMVRINKIGKKFGLKCELLAKCEFFNAGGSVKD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 RISLRMIEDAERDGTLKPGDTIIEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RISLRMIEDAERDGTLKPGDTIIEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 LRALGAEIVRTPTNARFDSPESHVGVAWRLKNEIPNSHILDQYRNASNPLAHYDTTADEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LRALGAEIVRTPTNARFDSPESHVGVAWRLKNEIPNSHILDQYRNASNPLAHYDTTADEI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 LQQCDGKLDMLVASVGTGGTITGIARKLKEKCPGCRIIGVDPEGSILAEPEELNQTEQTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LQQCDGKLDMLVASVGTGGTITGIARKLKEKCPGCRIIGVDPEGSILAEPEELNQTEQTT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 YEVEGIGYDFIPTVLDRTVVDKWFKSNDEEAFTFARMLIAQEGLLCGGSAGSTVAVAVKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YEVEGIGYDFIPTVLDRTVVDKWFKSNDEEAFTFARMLIAQEGLLCGGSAGSTVAVAVKA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 AQELQEGQRCVVILPDSVRNYMTKFLSDRWMLQKGFLKEEDLTEKKPWWWHLRVQELGLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AQELQEGQRCVVILPDSVRNYMTKFLSDRWMLQKGFLKEEDLTEKKPWWWHLRVQELGLS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB4 APLTVLPTITCGHTIEILREKGFDQAPVVDEAGVILGMVTLGNMLSSLLAGKVQPSDQVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 APLTVLPTITCGHTIEILREKGFDQAPVVDEAGVILGMVTLGNMLSSLLAGKVQPSDQVG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB4 KVIYKQFKQIRLTDTLGRLSHILEMDHFALVVHEQIQYHSTGKSSQRQMVFGVVTAIDLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KVIYKQFKQIRLTDTLGRLSHILEMDHFALVVHEQIQYHSTGKSSQRQMVFGVVTAIDLL 490 500 510 520 530 540 550 pF1KB4 NFVAAQERDQK ::::::::::: NP_001 NFVAAQERDQK 550 >>NP_001307227 (OMIM: 236200,613381) cystathionine beta- (551 aa) initn: 3684 init1: 3684 opt: 3684 Z-score: 3735.7 bits: 701.0 E(85289): 2.4e-201 Smith-Waterman score: 3684; 100.0% identity (100.0% similar) in 551 aa overlap (1-551:1-551) 10 20 30 40 50 60 pF1KB4 MPSETPQAEVGPTGCPHRSGPHSAKGSLEKGSPEDKEAKEPLWIRPDAPSRCTWQLGRPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MPSETPQAEVGPTGCPHRSGPHSAKGSLEKGSPEDKEAKEPLWIRPDAPSRCTWQLGRPA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 SESPHHHTAPAKSPKILPDILKKIGDTPMVRINKIGKKFGLKCELLAKCEFFNAGGSVKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SESPHHHTAPAKSPKILPDILKKIGDTPMVRINKIGKKFGLKCELLAKCEFFNAGGSVKD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 RISLRMIEDAERDGTLKPGDTIIEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RISLRMIEDAERDGTLKPGDTIIEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 LRALGAEIVRTPTNARFDSPESHVGVAWRLKNEIPNSHILDQYRNASNPLAHYDTTADEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LRALGAEIVRTPTNARFDSPESHVGVAWRLKNEIPNSHILDQYRNASNPLAHYDTTADEI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 LQQCDGKLDMLVASVGTGGTITGIARKLKEKCPGCRIIGVDPEGSILAEPEELNQTEQTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LQQCDGKLDMLVASVGTGGTITGIARKLKEKCPGCRIIGVDPEGSILAEPEELNQTEQTT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 YEVEGIGYDFIPTVLDRTVVDKWFKSNDEEAFTFARMLIAQEGLLCGGSAGSTVAVAVKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YEVEGIGYDFIPTVLDRTVVDKWFKSNDEEAFTFARMLIAQEGLLCGGSAGSTVAVAVKA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 AQELQEGQRCVVILPDSVRNYMTKFLSDRWMLQKGFLKEEDLTEKKPWWWHLRVQELGLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AQELQEGQRCVVILPDSVRNYMTKFLSDRWMLQKGFLKEEDLTEKKPWWWHLRVQELGLS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB4 APLTVLPTITCGHTIEILREKGFDQAPVVDEAGVILGMVTLGNMLSSLLAGKVQPSDQVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 APLTVLPTITCGHTIEILREKGFDQAPVVDEAGVILGMVTLGNMLSSLLAGKVQPSDQVG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB4 KVIYKQFKQIRLTDTLGRLSHILEMDHFALVVHEQIQYHSTGKSSQRQMVFGVVTAIDLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KVIYKQFKQIRLTDTLGRLSHILEMDHFALVVHEQIQYHSTGKSSQRQMVFGVVTAIDLL 490 500 510 520 530 540 550 pF1KB4 NFVAAQERDQK ::::::::::: NP_001 NFVAAQERDQK 550 >>NP_001171479 (OMIM: 236200,613381) cystathionine beta- (551 aa) initn: 3684 init1: 3684 opt: 3684 Z-score: 3735.7 bits: 701.0 E(85289): 2.4e-201 Smith-Waterman score: 3684; 100.0% identity (100.0% similar) in 551 aa overlap (1-551:1-551) 10 20 30 40 50 60 pF1KB4 MPSETPQAEVGPTGCPHRSGPHSAKGSLEKGSPEDKEAKEPLWIRPDAPSRCTWQLGRPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MPSETPQAEVGPTGCPHRSGPHSAKGSLEKGSPEDKEAKEPLWIRPDAPSRCTWQLGRPA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 SESPHHHTAPAKSPKILPDILKKIGDTPMVRINKIGKKFGLKCELLAKCEFFNAGGSVKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SESPHHHTAPAKSPKILPDILKKIGDTPMVRINKIGKKFGLKCELLAKCEFFNAGGSVKD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 RISLRMIEDAERDGTLKPGDTIIEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RISLRMIEDAERDGTLKPGDTIIEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 LRALGAEIVRTPTNARFDSPESHVGVAWRLKNEIPNSHILDQYRNASNPLAHYDTTADEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LRALGAEIVRTPTNARFDSPESHVGVAWRLKNEIPNSHILDQYRNASNPLAHYDTTADEI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 LQQCDGKLDMLVASVGTGGTITGIARKLKEKCPGCRIIGVDPEGSILAEPEELNQTEQTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LQQCDGKLDMLVASVGTGGTITGIARKLKEKCPGCRIIGVDPEGSILAEPEELNQTEQTT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 YEVEGIGYDFIPTVLDRTVVDKWFKSNDEEAFTFARMLIAQEGLLCGGSAGSTVAVAVKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YEVEGIGYDFIPTVLDRTVVDKWFKSNDEEAFTFARMLIAQEGLLCGGSAGSTVAVAVKA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 AQELQEGQRCVVILPDSVRNYMTKFLSDRWMLQKGFLKEEDLTEKKPWWWHLRVQELGLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AQELQEGQRCVVILPDSVRNYMTKFLSDRWMLQKGFLKEEDLTEKKPWWWHLRVQELGLS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB4 APLTVLPTITCGHTIEILREKGFDQAPVVDEAGVILGMVTLGNMLSSLLAGKVQPSDQVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 APLTVLPTITCGHTIEILREKGFDQAPVVDEAGVILGMVTLGNMLSSLLAGKVQPSDQVG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB4 KVIYKQFKQIRLTDTLGRLSHILEMDHFALVVHEQIQYHSTGKSSQRQMVFGVVTAIDLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KVIYKQFKQIRLTDTLGRLSHILEMDHFALVVHEQIQYHSTGKSSQRQMVFGVVTAIDLL 490 500 510 520 530 540 550 pF1KB4 NFVAAQERDQK ::::::::::: NP_001 NFVAAQERDQK 550 >>NP_000062 (OMIM: 236200,613381) cystathionine beta-syn (551 aa) initn: 3684 init1: 3684 opt: 3684 Z-score: 3735.7 bits: 701.0 E(85289): 2.4e-201 Smith-Waterman score: 3684; 100.0% identity (100.0% similar) in 551 aa overlap (1-551:1-551) 10 20 30 40 50 60 pF1KB4 MPSETPQAEVGPTGCPHRSGPHSAKGSLEKGSPEDKEAKEPLWIRPDAPSRCTWQLGRPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 MPSETPQAEVGPTGCPHRSGPHSAKGSLEKGSPEDKEAKEPLWIRPDAPSRCTWQLGRPA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 SESPHHHTAPAKSPKILPDILKKIGDTPMVRINKIGKKFGLKCELLAKCEFFNAGGSVKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 SESPHHHTAPAKSPKILPDILKKIGDTPMVRINKIGKKFGLKCELLAKCEFFNAGGSVKD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 RISLRMIEDAERDGTLKPGDTIIEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 RISLRMIEDAERDGTLKPGDTIIEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 LRALGAEIVRTPTNARFDSPESHVGVAWRLKNEIPNSHILDQYRNASNPLAHYDTTADEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 LRALGAEIVRTPTNARFDSPESHVGVAWRLKNEIPNSHILDQYRNASNPLAHYDTTADEI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 LQQCDGKLDMLVASVGTGGTITGIARKLKEKCPGCRIIGVDPEGSILAEPEELNQTEQTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 LQQCDGKLDMLVASVGTGGTITGIARKLKEKCPGCRIIGVDPEGSILAEPEELNQTEQTT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 YEVEGIGYDFIPTVLDRTVVDKWFKSNDEEAFTFARMLIAQEGLLCGGSAGSTVAVAVKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 YEVEGIGYDFIPTVLDRTVVDKWFKSNDEEAFTFARMLIAQEGLLCGGSAGSTVAVAVKA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 AQELQEGQRCVVILPDSVRNYMTKFLSDRWMLQKGFLKEEDLTEKKPWWWHLRVQELGLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 AQELQEGQRCVVILPDSVRNYMTKFLSDRWMLQKGFLKEEDLTEKKPWWWHLRVQELGLS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB4 APLTVLPTITCGHTIEILREKGFDQAPVVDEAGVILGMVTLGNMLSSLLAGKVQPSDQVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 APLTVLPTITCGHTIEILREKGFDQAPVVDEAGVILGMVTLGNMLSSLLAGKVQPSDQVG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB4 KVIYKQFKQIRLTDTLGRLSHILEMDHFALVVHEQIQYHSTGKSSQRQMVFGVVTAIDLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 KVIYKQFKQIRLTDTLGRLSHILEMDHFALVVHEQIQYHSTGKSSQRQMVFGVVTAIDLL 490 500 510 520 530 540 550 pF1KB4 NFVAAQERDQK ::::::::::: NP_000 NFVAAQERDQK 550 >>XP_016883981 (OMIM: 236200,613381) PREDICTED: cystathi (551 aa) initn: 3684 init1: 3684 opt: 3684 Z-score: 3735.7 bits: 701.0 E(85289): 2.4e-201 Smith-Waterman score: 3684; 100.0% identity (100.0% similar) in 551 aa overlap (1-551:1-551) 10 20 30 40 50 60 pF1KB4 MPSETPQAEVGPTGCPHRSGPHSAKGSLEKGSPEDKEAKEPLWIRPDAPSRCTWQLGRPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MPSETPQAEVGPTGCPHRSGPHSAKGSLEKGSPEDKEAKEPLWIRPDAPSRCTWQLGRPA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 SESPHHHTAPAKSPKILPDILKKIGDTPMVRINKIGKKFGLKCELLAKCEFFNAGGSVKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SESPHHHTAPAKSPKILPDILKKIGDTPMVRINKIGKKFGLKCELLAKCEFFNAGGSVKD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 RISLRMIEDAERDGTLKPGDTIIEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RISLRMIEDAERDGTLKPGDTIIEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 LRALGAEIVRTPTNARFDSPESHVGVAWRLKNEIPNSHILDQYRNASNPLAHYDTTADEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LRALGAEIVRTPTNARFDSPESHVGVAWRLKNEIPNSHILDQYRNASNPLAHYDTTADEI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 LQQCDGKLDMLVASVGTGGTITGIARKLKEKCPGCRIIGVDPEGSILAEPEELNQTEQTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQQCDGKLDMLVASVGTGGTITGIARKLKEKCPGCRIIGVDPEGSILAEPEELNQTEQTT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 YEVEGIGYDFIPTVLDRTVVDKWFKSNDEEAFTFARMLIAQEGLLCGGSAGSTVAVAVKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YEVEGIGYDFIPTVLDRTVVDKWFKSNDEEAFTFARMLIAQEGLLCGGSAGSTVAVAVKA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 AQELQEGQRCVVILPDSVRNYMTKFLSDRWMLQKGFLKEEDLTEKKPWWWHLRVQELGLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AQELQEGQRCVVILPDSVRNYMTKFLSDRWMLQKGFLKEEDLTEKKPWWWHLRVQELGLS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB4 APLTVLPTITCGHTIEILREKGFDQAPVVDEAGVILGMVTLGNMLSSLLAGKVQPSDQVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 APLTVLPTITCGHTIEILREKGFDQAPVVDEAGVILGMVTLGNMLSSLLAGKVQPSDQVG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB4 KVIYKQFKQIRLTDTLGRLSHILEMDHFALVVHEQIQYHSTGKSSQRQMVFGVVTAIDLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KVIYKQFKQIRLTDTLGRLSHILEMDHFALVVHEQIQYHSTGKSSQRQMVFGVVTAIDLL 490 500 510 520 530 540 550 pF1KB4 NFVAAQERDQK ::::::::::: XP_016 NFVAAQERDQK 550 >>XP_016883980 (OMIM: 236200,613381) PREDICTED: cystathi (551 aa) initn: 3684 init1: 3684 opt: 3684 Z-score: 3735.7 bits: 701.0 E(85289): 2.4e-201 Smith-Waterman score: 3684; 100.0% identity (100.0% similar) in 551 aa overlap (1-551:1-551) 10 20 30 40 50 60 pF1KB4 MPSETPQAEVGPTGCPHRSGPHSAKGSLEKGSPEDKEAKEPLWIRPDAPSRCTWQLGRPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MPSETPQAEVGPTGCPHRSGPHSAKGSLEKGSPEDKEAKEPLWIRPDAPSRCTWQLGRPA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 SESPHHHTAPAKSPKILPDILKKIGDTPMVRINKIGKKFGLKCELLAKCEFFNAGGSVKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SESPHHHTAPAKSPKILPDILKKIGDTPMVRINKIGKKFGLKCELLAKCEFFNAGGSVKD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 RISLRMIEDAERDGTLKPGDTIIEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RISLRMIEDAERDGTLKPGDTIIEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 LRALGAEIVRTPTNARFDSPESHVGVAWRLKNEIPNSHILDQYRNASNPLAHYDTTADEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LRALGAEIVRTPTNARFDSPESHVGVAWRLKNEIPNSHILDQYRNASNPLAHYDTTADEI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 LQQCDGKLDMLVASVGTGGTITGIARKLKEKCPGCRIIGVDPEGSILAEPEELNQTEQTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQQCDGKLDMLVASVGTGGTITGIARKLKEKCPGCRIIGVDPEGSILAEPEELNQTEQTT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 YEVEGIGYDFIPTVLDRTVVDKWFKSNDEEAFTFARMLIAQEGLLCGGSAGSTVAVAVKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YEVEGIGYDFIPTVLDRTVVDKWFKSNDEEAFTFARMLIAQEGLLCGGSAGSTVAVAVKA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 AQELQEGQRCVVILPDSVRNYMTKFLSDRWMLQKGFLKEEDLTEKKPWWWHLRVQELGLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AQELQEGQRCVVILPDSVRNYMTKFLSDRWMLQKGFLKEEDLTEKKPWWWHLRVQELGLS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB4 APLTVLPTITCGHTIEILREKGFDQAPVVDEAGVILGMVTLGNMLSSLLAGKVQPSDQVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 APLTVLPTITCGHTIEILREKGFDQAPVVDEAGVILGMVTLGNMLSSLLAGKVQPSDQVG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB4 KVIYKQFKQIRLTDTLGRLSHILEMDHFALVVHEQIQYHSTGKSSQRQMVFGVVTAIDLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KVIYKQFKQIRLTDTLGRLSHILEMDHFALVVHEQIQYHSTGKSSQRQMVFGVVTAIDLL 490 500 510 520 530 540 550 pF1KB4 NFVAAQERDQK ::::::::::: XP_016 NFVAAQERDQK 550 >>XP_016883978 (OMIM: 236200,613381) PREDICTED: cystathi (565 aa) initn: 3662 init1: 3469 opt: 3473 Z-score: 3521.8 bits: 661.5 E(85289): 2e-189 Smith-Waterman score: 3636; 97.3% identity (97.3% similar) in 565 aa overlap (1-551:1-565) 10 20 30 40 50 60 pF1KB4 MPSETPQAEVGPTGCPHRSGPHSAKGSLEKGSPEDKEAKEPLWIRPDAPSRCTWQLGRPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MPSETPQAEVGPTGCPHRSGPHSAKGSLEKGSPEDKEAKEPLWIRPDAPSRCTWQLGRPA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 SESPHHHTAPAKSPKILPDILKKIGDTPMVRINKIGKKFGLKCELLAKCEFFNAGGSVKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SESPHHHTAPAKSPKILPDILKKIGDTPMVRINKIGKKFGLKCELLAKCEFFNAGGSVKD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 RISLRMIEDAERDGTLKPGDTIIEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RISLRMIEDAERDGTLKPGDTIIEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 LRALGAEIVRTPTNARFDSPESHVGVAWRLKNEIPNSHILDQYRNASNPLAHYDTTADEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LRALGAEIVRTPTNARFDSPESHVGVAWRLKNEIPNSHILDQYRNASNPLAHYDTTADEI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 LQQCDGKLDMLVASVGTGGTITGIARKLKEKCPGCRIIGVDPEGSILAEPEELNQTEQTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQQCDGKLDMLVASVGTGGTITGIARKLKEKCPGCRIIGVDPEGSILAEPEELNQTEQTT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 YEVEGIGYDFIPTVLDRTVVDKWFKSNDEEAFTFARMLIAQEGLLCGGSAGSTVAVAVKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YEVEGIGYDFIPTVLDRTVVDKWFKSNDEEAFTFARMLIAQEGLLCGGSAGSTVAVAVKA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 AQELQEGQRCVVILPDSVRNYMTKFLSDRWMLQKGFLKEEDLTEKKPWWWHLRVQELGLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AQELQEGQRCVVILPDSVRNYMTKFLSDRWMLQKGFLKEEDLTEKKPWWWHLRVQELGLS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB4 APLTVLPTITCGHTIEILREKGFDQAPVVDEAGVILGMVTLGNMLSSLLAGKVQPSDQVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 APLTVLPTITCGHTIEILREKGFDQAPVVDEAGVILGMVTLGNMLSSLLAGKVQPSDQVG 430 440 450 460 470 480 490 500 510 520 pF1KB4 KVIYKQFKQIRLTDTLGRLSHILEMDHFALVVHEQIQY--------------HSTGKSSQ ::::::::::::::::::::::::::::::::::::: :::::::: XP_016 KVIYKQFKQIRLTDTLGRLSHILEMDHFALVVHEQIQSQDQAWAGVVGGPADHSTGKSSQ 490 500 510 520 530 540 530 540 550 pF1KB4 RQMVFGVVTAIDLLNFVAAQERDQK ::::::::::::::::::::::::: XP_016 RQMVFGVVTAIDLLNFVAAQERDQK 550 560 >>XP_011528079 (OMIM: 236200,613381) PREDICTED: cystathi (565 aa) initn: 3662 init1: 3469 opt: 3473 Z-score: 3521.8 bits: 661.5 E(85289): 2e-189 Smith-Waterman score: 3636; 97.3% identity (97.3% similar) in 565 aa overlap (1-551:1-565) 10 20 30 40 50 60 pF1KB4 MPSETPQAEVGPTGCPHRSGPHSAKGSLEKGSPEDKEAKEPLWIRPDAPSRCTWQLGRPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MPSETPQAEVGPTGCPHRSGPHSAKGSLEKGSPEDKEAKEPLWIRPDAPSRCTWQLGRPA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 SESPHHHTAPAKSPKILPDILKKIGDTPMVRINKIGKKFGLKCELLAKCEFFNAGGSVKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SESPHHHTAPAKSPKILPDILKKIGDTPMVRINKIGKKFGLKCELLAKCEFFNAGGSVKD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 RISLRMIEDAERDGTLKPGDTIIEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RISLRMIEDAERDGTLKPGDTIIEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 LRALGAEIVRTPTNARFDSPESHVGVAWRLKNEIPNSHILDQYRNASNPLAHYDTTADEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LRALGAEIVRTPTNARFDSPESHVGVAWRLKNEIPNSHILDQYRNASNPLAHYDTTADEI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 LQQCDGKLDMLVASVGTGGTITGIARKLKEKCPGCRIIGVDPEGSILAEPEELNQTEQTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQQCDGKLDMLVASVGTGGTITGIARKLKEKCPGCRIIGVDPEGSILAEPEELNQTEQTT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 YEVEGIGYDFIPTVLDRTVVDKWFKSNDEEAFTFARMLIAQEGLLCGGSAGSTVAVAVKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YEVEGIGYDFIPTVLDRTVVDKWFKSNDEEAFTFARMLIAQEGLLCGGSAGSTVAVAVKA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 AQELQEGQRCVVILPDSVRNYMTKFLSDRWMLQKGFLKEEDLTEKKPWWWHLRVQELGLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AQELQEGQRCVVILPDSVRNYMTKFLSDRWMLQKGFLKEEDLTEKKPWWWHLRVQELGLS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB4 APLTVLPTITCGHTIEILREKGFDQAPVVDEAGVILGMVTLGNMLSSLLAGKVQPSDQVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 APLTVLPTITCGHTIEILREKGFDQAPVVDEAGVILGMVTLGNMLSSLLAGKVQPSDQVG 430 440 450 460 470 480 490 500 510 520 pF1KB4 KVIYKQFKQIRLTDTLGRLSHILEMDHFALVVHEQIQY--------------HSTGKSSQ ::::::::::::::::::::::::::::::::::::: :::::::: XP_011 KVIYKQFKQIRLTDTLGRLSHILEMDHFALVVHEQIQSQDQAWAGVVGGPADHSTGKSSQ 490 500 510 520 530 540 530 540 550 pF1KB4 RQMVFGVVTAIDLLNFVAAQERDQK ::::::::::::::::::::::::: XP_011 RQMVFGVVTAIDLLNFVAAQERDQK 550 560 >>XP_011528084 (OMIM: 236200,613381) PREDICTED: cystathi (565 aa) initn: 3662 init1: 3469 opt: 3473 Z-score: 3521.8 bits: 661.5 E(85289): 2e-189 Smith-Waterman score: 3636; 97.3% identity (97.3% similar) in 565 aa overlap (1-551:1-565) 10 20 30 40 50 60 pF1KB4 MPSETPQAEVGPTGCPHRSGPHSAKGSLEKGSPEDKEAKEPLWIRPDAPSRCTWQLGRPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MPSETPQAEVGPTGCPHRSGPHSAKGSLEKGSPEDKEAKEPLWIRPDAPSRCTWQLGRPA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 SESPHHHTAPAKSPKILPDILKKIGDTPMVRINKIGKKFGLKCELLAKCEFFNAGGSVKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SESPHHHTAPAKSPKILPDILKKIGDTPMVRINKIGKKFGLKCELLAKCEFFNAGGSVKD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 RISLRMIEDAERDGTLKPGDTIIEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RISLRMIEDAERDGTLKPGDTIIEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 LRALGAEIVRTPTNARFDSPESHVGVAWRLKNEIPNSHILDQYRNASNPLAHYDTTADEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LRALGAEIVRTPTNARFDSPESHVGVAWRLKNEIPNSHILDQYRNASNPLAHYDTTADEI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 LQQCDGKLDMLVASVGTGGTITGIARKLKEKCPGCRIIGVDPEGSILAEPEELNQTEQTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQQCDGKLDMLVASVGTGGTITGIARKLKEKCPGCRIIGVDPEGSILAEPEELNQTEQTT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 YEVEGIGYDFIPTVLDRTVVDKWFKSNDEEAFTFARMLIAQEGLLCGGSAGSTVAVAVKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YEVEGIGYDFIPTVLDRTVVDKWFKSNDEEAFTFARMLIAQEGLLCGGSAGSTVAVAVKA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 AQELQEGQRCVVILPDSVRNYMTKFLSDRWMLQKGFLKEEDLTEKKPWWWHLRVQELGLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AQELQEGQRCVVILPDSVRNYMTKFLSDRWMLQKGFLKEEDLTEKKPWWWHLRVQELGLS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB4 APLTVLPTITCGHTIEILREKGFDQAPVVDEAGVILGMVTLGNMLSSLLAGKVQPSDQVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 APLTVLPTITCGHTIEILREKGFDQAPVVDEAGVILGMVTLGNMLSSLLAGKVQPSDQVG 430 440 450 460 470 480 490 500 510 520 pF1KB4 KVIYKQFKQIRLTDTLGRLSHILEMDHFALVVHEQIQY--------------HSTGKSSQ ::::::::::::::::::::::::::::::::::::: :::::::: XP_011 KVIYKQFKQIRLTDTLGRLSHILEMDHFALVVHEQIQSQDQAWAGVVGGPADHSTGKSSQ 490 500 510 520 530 540 530 540 550 pF1KB4 RQMVFGVVTAIDLLNFVAAQERDQK ::::::::::::::::::::::::: XP_011 RQMVFGVVTAIDLLNFVAAQERDQK 550 560 551 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 05:32:01 2016 done: Sat Nov 5 05:32:02 2016 Total Scan time: 9.850 Total Display time: 0.100 Function used was FASTA [36.3.4 Apr, 2011]