FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4014, 469 aa 1>>>pF1KB4014 469 - 469 aa - 469 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 11.2007+/-0.00115; mu= -7.8865+/- 0.068 mean_var=457.8477+/-101.144, 0's: 0 Z-trim(114.4): 649 B-trim: 818 in 1/53 Lambda= 0.059940 statistics sampled from 14224 (14995) to 14224 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.77), E-opt: 0.2 (0.461), width: 16 Scan time: 3.810 The best scores are: opt bits E(32554) CCDS47905.1 KLF10 gene_id:7071|Hs108|chr8 ( 469) 3229 293.6 2.9e-79 CCDS6294.1 KLF10 gene_id:7071|Hs108|chr8 ( 480) 3222 293.1 4.4e-79 CCDS54333.1 KLF11 gene_id:8462|Hs108|chr2 ( 495) 904 92.6 9.9e-19 CCDS1668.1 KLF11 gene_id:8462|Hs108|chr2 ( 512) 904 92.6 1e-18 >>CCDS47905.1 KLF10 gene_id:7071|Hs108|chr8 (469 aa) initn: 3229 init1: 3229 opt: 3229 Z-score: 1536.6 bits: 293.6 E(32554): 2.9e-79 Smith-Waterman score: 3229; 100.0% identity (100.0% similar) in 469 aa overlap (1-469:1-469) 10 20 30 40 50 60 pF1KB4 MEERMEMISERPKESMYSWNKTAEKSDFEAVEALMSMSCSWKSDFKKYVENRPVTPVSDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 MEERMEMISERPKESMYSWNKTAEKSDFEAVEALMSMSCSWKSDFKKYVENRPVTPVSDL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 SEEENLLPGTPDFHTIPAFCLTPPYSPSDFEPSQVSNLMAPAPSTVHFKSLSDTAKPHIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 SEEENLLPGTPDFHTIPAFCLTPPYSPSDFEPSQVSNLMAPAPSTVHFKSLSDTAKPHIA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 APFKEEEKSPVSAPKLPKAQATSVIRHTADAQLCNHQTCPMKAASILNYQNNSFRRRTHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 APFKEEEKSPVSAPKLPKAQATSVIRHTADAQLCNHQTCPMKAASILNYQNNSFRRRTHL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 NVEAARKNIPCAAVSPNRSKCERNTVADVDEKASAALYDFSVPSSETVICRSQPAPVSPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 NVEAARKNIPCAAVSPNRSKCERNTVADVDEKASAALYDFSVPSSETVICRSQPAPVSPQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 QKSVLVSPPAVSAGGVPPMPVICQMVPLPANNPVVTTVVPSTPPSQPPAVCPPVVFMGTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 QKSVLVSPPAVSAGGVPPMPVICQMVPLPANNPVVTTVVPSTPPSQPPAVCPPVVFMGTQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 VPKGAVMFVVPQPVVQSSKPPVVSPNGTRLSPIAPAPGFSPSAAKVTPQIDSSRIRSHIC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 VPKGAVMFVVPQPVVQSSKPPVVSPNGTRLSPIAPAPGFSPSAAKVTPQIDSSRIRSHIC 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 SHPGCGKTYFKSSHLKAHTRTHTGEKPFSCSWKGCERRFARSDELSRHRRTHTGEKKFAC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 SHPGCGKTYFKSSHLKAHTRTHTGEKPFSCSWKGCERRFARSDELSRHRRTHTGEKKFAC 370 380 390 400 410 420 430 440 450 460 pF1KB4 PMCDRRFMRSDHLTKHARRHLSAKKLPNWQMEVSKLNDIALPPTPAPTQ ::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 PMCDRRFMRSDHLTKHARRHLSAKKLPNWQMEVSKLNDIALPPTPAPTQ 430 440 450 460 >>CCDS6294.1 KLF10 gene_id:7071|Hs108|chr8 (480 aa) initn: 3222 init1: 3222 opt: 3222 Z-score: 1533.2 bits: 293.1 E(32554): 4.4e-79 Smith-Waterman score: 3222; 100.0% identity (100.0% similar) in 468 aa overlap (2-469:13-480) 10 20 30 40 pF1KB4 MEERMEMISERPKESMYSWNKTAEKSDFEAVEALMSMSCSWKSDFKKYV :::::::::::::::::::::::::::::::::::::::::::::::: CCDS62 MLNFGASLQQTAEERMEMISERPKESMYSWNKTAEKSDFEAVEALMSMSCSWKSDFKKYV 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB4 ENRPVTPVSDLSEEENLLPGTPDFHTIPAFCLTPPYSPSDFEPSQVSNLMAPAPSTVHFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS62 ENRPVTPVSDLSEEENLLPGTPDFHTIPAFCLTPPYSPSDFEPSQVSNLMAPAPSTVHFK 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB4 SLSDTAKPHIAAPFKEEEKSPVSAPKLPKAQATSVIRHTADAQLCNHQTCPMKAASILNY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS62 SLSDTAKPHIAAPFKEEEKSPVSAPKLPKAQATSVIRHTADAQLCNHQTCPMKAASILNY 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB4 QNNSFRRRTHLNVEAARKNIPCAAVSPNRSKCERNTVADVDEKASAALYDFSVPSSETVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS62 QNNSFRRRTHLNVEAARKNIPCAAVSPNRSKCERNTVADVDEKASAALYDFSVPSSETVI 190 200 210 220 230 240 230 240 250 260 270 280 pF1KB4 CRSQPAPVSPQQKSVLVSPPAVSAGGVPPMPVICQMVPLPANNPVVTTVVPSTPPSQPPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS62 CRSQPAPVSPQQKSVLVSPPAVSAGGVPPMPVICQMVPLPANNPVVTTVVPSTPPSQPPA 250 260 270 280 290 300 290 300 310 320 330 340 pF1KB4 VCPPVVFMGTQVPKGAVMFVVPQPVVQSSKPPVVSPNGTRLSPIAPAPGFSPSAAKVTPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS62 VCPPVVFMGTQVPKGAVMFVVPQPVVQSSKPPVVSPNGTRLSPIAPAPGFSPSAAKVTPQ 310 320 330 340 350 360 350 360 370 380 390 400 pF1KB4 IDSSRIRSHICSHPGCGKTYFKSSHLKAHTRTHTGEKPFSCSWKGCERRFARSDELSRHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS62 IDSSRIRSHICSHPGCGKTYFKSSHLKAHTRTHTGEKPFSCSWKGCERRFARSDELSRHR 370 380 390 400 410 420 410 420 430 440 450 460 pF1KB4 RTHTGEKKFACPMCDRRFMRSDHLTKHARRHLSAKKLPNWQMEVSKLNDIALPPTPAPTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS62 RTHTGEKKFACPMCDRRFMRSDHLTKHARRHLSAKKLPNWQMEVSKLNDIALPPTPAPTQ 430 440 450 460 470 480 >>CCDS54333.1 KLF11 gene_id:8462|Hs108|chr2 (495 aa) initn: 942 init1: 740 opt: 904 Z-score: 449.7 bits: 92.6 E(32554): 9.9e-19 Smith-Waterman score: 1046; 40.3% identity (61.9% similar) in 494 aa overlap (6-465:5-484) 10 20 30 40 50 pF1KB4 MEERMEMISERPK-ESMYSWNKTAEKSDFEAVEALMSMSCSWKSDFKK--YVENRPVTPV : : :: . .: : . :..:.::::::. :: :: . .: .. ::.::: CCDS54 MDICESILERKRHDSERSTCSILEQTDMEAVEALVCMS-SWGQRSQKGDLLRIRPLTPV 10 20 30 40 50 60 70 80 90 100 pF1KB4 SD---LSEEENLLPGTP----DFHTIPAFCLTPPYSPSDFEPSQ---VSNLMAPAPSTVH :: .. .. .:: :::.. ..:.::: ::. ::: :: .. . . . CCDS54 SDSGDVTTTVHMDAATPELPKDFHSLSTLCITPPQSPDLVEPSTRTPVSPQVTDSKACTA 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB4 FKSLSDTAKPHIAAPFKEEEK----SPVSAPKLP-KAQATSVIRHTADAQLCNHQTCPMK :...: : :. :: :. : .:..:::::::... : CCDS54 TDVLQSSAVVARALSGGAERGLLGLEPV--PSSPCRAKGTSVIRHTGESPAACFPTIQTP 120 130 140 150 160 170 170 180 190 200 210 pF1KB4 AASILNYQNNSFRRRTHLNVEAARKNIPCAAVSPNRSKCE----RNTVADVDEKASAALY . . ... . :... .. . .: : .:. .. . .:.. : . CCDS54 DCRLSDSREGEEQLLGHFET-LQDTHLTDSLLSTNLVSCQPCLHKSGGLLLTDKGQQAGW 180 190 200 210 220 230 220 230 240 250 260 270 pF1KB4 DFSVPSSETVICRSQPAPVSPQQKSVLVSPPAVSAGGVPPMPVICQMVP-------LPA- .: . : .: . .. . : .:.. :: ::.:::.: ::: CCDS54 PGAVQT-----C----SPKNYENDLPRKTTPLISVS-VPAPPVLCQMIPVTGQSSMLPAF 240 250 260 270 280 280 290 300 310 320 pF1KB4 -NNPVVTTVVPSTPPSQPPAVCPPVVFMGTQVPKGAVMFVVPQPVVQSSKP---PVVSPN . : .: : : : ::.: ::.::::.:.:: .. : :.. . CCDS54 LKPPPQLSVGTVRPILAQAAPAPQPVFVGPAVPQGAVMLVLPQGALPPPAPCAANVMAAG 290 300 310 320 330 340 330 340 350 360 370 380 pF1KB4 GTRLSPIAPAPGFSPSAAKVTPQIDSSRIRSHICSHPGCGKTYFKSSHLKAHTRTHTGEK .:.: :.:::: : :. . .::.: :: :...:: ::: :::::::::::: ::::::: CCDS54 NTKLLPLAPAPVFITSSQNCVPQVDFSRRRNYVCSFPGCRKTYFKSSHLKAHLRTHTGEK 350 360 370 380 390 400 390 400 410 420 430 440 pF1KB4 PFSCSWKGCERRFARSDELSRHRRTHTGEKKFACPMCDRRFMRSDHLTKHARRHLSAKKL ::.::: ::...::::::::::::::::::::.::.::::::::::::::::::...::. CCDS54 PFNCSWDGCDKKFARSDELSRHRRTHTGEKKFVCPVCDRRFMRSDHLTKHARRHMTTKKI 410 420 430 440 450 460 450 460 pF1KB4 PNWQMEVSKLNDIALPPTPAPTQ :.:: ::.::: :: .: CCDS54 PGWQAEVGKLNRIASAESPGSPLVSMPASA 470 480 490 >>CCDS1668.1 KLF11 gene_id:8462|Hs108|chr2 (512 aa) initn: 942 init1: 740 opt: 904 Z-score: 449.6 bits: 92.6 E(32554): 1e-18 Smith-Waterman score: 1046; 40.3% identity (61.9% similar) in 494 aa overlap (6-465:22-501) 10 20 30 40 pF1KB4 MEERMEMISERPK-ESMYSWNKTAEKSDFEAVEALMSMSCSWKS : : :: . .: : . :..:.::::::. :: :: . CCDS16 MHTPDFAGPDDARAVDIMDICESILERKRHDSERSTCSILEQTDMEAVEALVCMS-SWGQ 10 20 30 40 50 50 60 70 80 90 pF1KB4 DFKK--YVENRPVTPVSD---LSEEENLLPGTP----DFHTIPAFCLTPPYSPSDFEPSQ .: .. ::.::::: .. .. .:: :::.. ..:.::: ::. ::: CCDS16 RSQKGDLLRIRPLTPVSDSGDVTTTVHMDAATPELPKDFHSLSTLCITPPQSPDLVEPST 60 70 80 90 100 110 100 110 120 130 140 pF1KB4 ---VSNLMAPAPSTVHFKSLSDTAKPHIAAPFKEEEK----SPVSAPKLP-KAQATSVIR :: .. . . . :...: : :. :: :. : .:..::::: CCDS16 RTPVSPQVTDSKACTATDVLQSSAVVARALSGGAERGLLGLEPV--PSSPCRAKGTSVIR 120 130 140 150 160 170 150 160 170 180 190 200 pF1KB4 HTADAQLCNHQTCPMKAASILNYQNNSFRRRTHLNVEAARKNIPCAAVSPNRSKCE---- ::... : . . ... . :... .. . .: : .:. CCDS16 HTGESPAACFPTIQTPDCRLSDSREGEEQLLGHFET-LQDTHLTDSLLSTNLVSCQPCLH 180 190 200 210 220 230 210 220 230 240 250 260 pF1KB4 RNTVADVDEKASAALYDFSVPSSETVICRSQPAPVSPQQKSVLVSPPAVSAGGVPPMPVI .. . .:.. : . .: . : .: . .. . : .:.. :: ::. CCDS16 KSGGLLLTDKGQQAGWPGAVQT-----C----SPKNYENDLPRKTTPLISVS-VPAPPVL 240 250 260 270 280 270 280 290 300 310 pF1KB4 CQMVP-------LPA--NNPVVTTVVPSTPPSQPPAVCPPVVFMGTQVPKGAVMFVVPQP :::.: ::: . : .: : : : ::.: ::.::::.:.:: CCDS16 CQMIPVTGQSSMLPAFLKPPPQLSVGTVRPILAQAAPAPQPVFVGPAVPQGAVMLVLPQG 290 300 310 320 330 340 320 330 340 350 360 370 pF1KB4 VVQSSKP---PVVSPNGTRLSPIAPAPGFSPSAAKVTPQIDSSRIRSHICSHPGCGKTYF .. : :.. ..:.: :.:::: : :. . .::.: :: :...:: ::: :::: CCDS16 ALPPPAPCAANVMAAGNTKLLPLAPAPVFITSSQNCVPQVDFSRRRNYVCSFPGCRKTYF 350 360 370 380 390 400 380 390 400 410 420 430 pF1KB4 KSSHLKAHTRTHTGEKPFSCSWKGCERRFARSDELSRHRRTHTGEKKFACPMCDRRFMRS :::::::: :::::::::.::: ::...::::::::::::::::::::.::.:::::::: CCDS16 KSSHLKAHLRTHTGEKPFNCSWDGCDKKFARSDELSRHRRTHTGEKKFVCPVCDRRFMRS 410 420 430 440 450 460 440 450 460 pF1KB4 DHLTKHARRHLSAKKLPNWQMEVSKLNDIALPPTPAPTQ ::::::::::...::.:.:: ::.::: :: .: CCDS16 DHLTKHARRHMTTKKIPGWQAEVGKLNRIASAESPGSPLVSMPASA 470 480 490 500 510 469 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 14:12:38 2016 done: Thu Nov 3 14:12:38 2016 Total Scan time: 3.810 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]