FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4014, 469 aa 1>>>pF1KB4014 469 - 469 aa - 469 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 11.9918+/-0.000475; mu= -11.2608+/- 0.029 mean_var=653.8275+/-153.191, 0's: 0 Z-trim(122.2): 721 B-trim: 2237 in 1/59 Lambda= 0.050158 statistics sampled from 38678 (40018) to 38678 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.769), E-opt: 0.2 (0.469), width: 16 Scan time: 11.420 The best scores are: opt bits E(85289) NP_001027453 (OMIM: 601878) Krueppel-like factor 1 ( 469) 3229 248.8 2.4e-65 NP_005646 (OMIM: 601878) Krueppel-like factor 10 i ( 480) 3222 248.3 3.4e-65 NP_001171187 (OMIM: 603301,610508) Krueppel-like f ( 495) 904 80.6 1.1e-14 NP_001171189 (OMIM: 603301,610508) Krueppel-like f ( 495) 904 80.6 1.1e-14 NP_003588 (OMIM: 603301,610508) Krueppel-like fact ( 512) 904 80.6 1.1e-14 NP_114124 (OMIM: 606139) Krueppel-like factor 16 [ ( 252) 542 54.0 5.5e-07 NP_057079 (OMIM: 605328,612001) Krueppel-like fact ( 288) 520 52.5 1.8e-06 XP_005247457 (OMIM: 606465) PREDICTED: Krueppel-li ( 416) 520 52.7 2.3e-06 NP_054798 (OMIM: 606465) Krueppel-like factor 15 [ ( 416) 520 52.7 2.3e-06 XP_011511045 (OMIM: 606465) PREDICTED: Krueppel-li ( 435) 520 52.7 2.3e-06 XP_011525944 (OMIM: 111150,600599,613566,613673) P ( 324) 515 52.2 2.5e-06 NP_006554 (OMIM: 111150,600599,613566,613673) Krue ( 362) 515 52.3 2.7e-06 NP_001197 (OMIM: 602902) Krueppel-like factor 9 [H ( 244) 497 50.7 5.2e-06 NP_619638 (OMIM: 609393) Krueppel-like factor 14 [ ( 323) 492 50.5 7.9e-06 NP_001273747 (OMIM: 602903) Krueppel-like factor 5 ( 366) 480 49.7 1.6e-05 NP_057354 (OMIM: 602016) Krueppel-like factor 2 [H ( 355) 478 49.6 1.7e-05 XP_016884739 (OMIM: 300286) PREDICTED: Krueppel-li ( 354) 477 49.5 1.8e-05 XP_011529061 (OMIM: 300286) PREDICTED: Krueppel-li ( 354) 477 49.5 1.8e-05 NP_001721 (OMIM: 602903) Krueppel-like factor 5 is ( 457) 480 49.9 1.8e-05 NP_001311034 (OMIM: 300286) Krueppel-like factor 8 ( 356) 477 49.5 1.8e-05 NP_009181 (OMIM: 300286) Krueppel-like factor 8 is ( 359) 477 49.5 1.8e-05 XP_005262034 (OMIM: 300286) PREDICTED: Krueppel-li ( 359) 477 49.5 1.8e-05 NP_001311031 (OMIM: 300286) Krueppel-like factor 8 ( 359) 477 49.5 1.8e-05 XP_005262036 (OMIM: 300286) PREDICTED: Krueppel-li ( 359) 477 49.5 1.8e-05 NP_001311033 (OMIM: 300286) Krueppel-like factor 8 ( 364) 477 49.5 1.8e-05 NP_945194 (OMIM: 608306) transcription factor Sp8 ( 490) 474 49.5 2.5e-05 NP_874359 (OMIM: 608306) transcription factor Sp8 ( 508) 474 49.5 2.6e-05 NP_001238754 (OMIM: 189906) transcription factor S ( 737) 477 49.9 2.8e-05 NP_001313472 (OMIM: 600540) transcription factor S ( 471) 471 49.2 2.8e-05 NP_003100 (OMIM: 189906) transcription factor Sp1 ( 778) 477 50.0 2.8e-05 XP_011536998 (OMIM: 189906) PREDICTED: transcripti ( 778) 477 50.0 2.8e-05 NP_612482 (OMIM: 189906) transcription factor Sp1 ( 785) 477 50.0 2.9e-05 NP_001003845 (OMIM: 609391) transcription factor S ( 398) 465 48.7 3.5e-05 XP_005246599 (OMIM: 609391) PREDICTED: transcripti ( 442) 465 48.8 3.7e-05 XP_011509461 (OMIM: 609391) PREDICTED: transcripti ( 454) 465 48.8 3.8e-05 XP_005249885 (OMIM: 600540) PREDICTED: transcripti ( 767) 471 49.5 3.8e-05 NP_001313471 (OMIM: 600540) transcription factor S ( 767) 471 49.5 3.8e-05 NP_003103 (OMIM: 600540) transcription factor Sp4 ( 784) 471 49.5 3.9e-05 XP_016863768 (OMIM: 609392) PREDICTED: Krueppel-li ( 320) 460 48.2 3.9e-05 NP_001300981 (OMIM: 602253) Krueppel-like factor 4 ( 513) 465 48.8 4e-05 NP_057615 (OMIM: 609392) Krueppel-like factor 3 [H ( 345) 460 48.3 4.1e-05 XP_016875874 (OMIM: 607531) PREDICTED: Krueppel-li ( 352) 459 48.2 4.4e-05 XP_011533214 (OMIM: 607531) PREDICTED: Krueppel-li ( 383) 459 48.2 4.6e-05 XP_011533213 (OMIM: 607531) PREDICTED: Krueppel-li ( 383) 459 48.2 4.6e-05 XP_016875873 (OMIM: 607531) PREDICTED: Krueppel-li ( 393) 459 48.3 4.7e-05 NP_001017371 (OMIM: 601804) transcription factor S ( 713) 466 49.1 4.7e-05 XP_011533212 (OMIM: 607531) PREDICTED: Krueppel-li ( 400) 459 48.3 4.7e-05 XP_011533211 (OMIM: 607531) PREDICTED: Krueppel-li ( 402) 459 48.3 4.7e-05 XP_005266308 (OMIM: 607531) PREDICTED: Krueppel-li ( 402) 459 48.3 4.7e-05 NP_009180 (OMIM: 607531) Krueppel-like factor 12 [ ( 402) 459 48.3 4.7e-05 >>NP_001027453 (OMIM: 601878) Krueppel-like factor 10 is (469 aa) initn: 3229 init1: 3229 opt: 3229 Z-score: 1294.3 bits: 248.8 E(85289): 2.4e-65 Smith-Waterman score: 3229; 100.0% identity (100.0% similar) in 469 aa overlap (1-469:1-469) 10 20 30 40 50 60 pF1KB4 MEERMEMISERPKESMYSWNKTAEKSDFEAVEALMSMSCSWKSDFKKYVENRPVTPVSDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MEERMEMISERPKESMYSWNKTAEKSDFEAVEALMSMSCSWKSDFKKYVENRPVTPVSDL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 SEEENLLPGTPDFHTIPAFCLTPPYSPSDFEPSQVSNLMAPAPSTVHFKSLSDTAKPHIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SEEENLLPGTPDFHTIPAFCLTPPYSPSDFEPSQVSNLMAPAPSTVHFKSLSDTAKPHIA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 APFKEEEKSPVSAPKLPKAQATSVIRHTADAQLCNHQTCPMKAASILNYQNNSFRRRTHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 APFKEEEKSPVSAPKLPKAQATSVIRHTADAQLCNHQTCPMKAASILNYQNNSFRRRTHL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 NVEAARKNIPCAAVSPNRSKCERNTVADVDEKASAALYDFSVPSSETVICRSQPAPVSPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NVEAARKNIPCAAVSPNRSKCERNTVADVDEKASAALYDFSVPSSETVICRSQPAPVSPQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 QKSVLVSPPAVSAGGVPPMPVICQMVPLPANNPVVTTVVPSTPPSQPPAVCPPVVFMGTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QKSVLVSPPAVSAGGVPPMPVICQMVPLPANNPVVTTVVPSTPPSQPPAVCPPVVFMGTQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 VPKGAVMFVVPQPVVQSSKPPVVSPNGTRLSPIAPAPGFSPSAAKVTPQIDSSRIRSHIC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VPKGAVMFVVPQPVVQSSKPPVVSPNGTRLSPIAPAPGFSPSAAKVTPQIDSSRIRSHIC 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 SHPGCGKTYFKSSHLKAHTRTHTGEKPFSCSWKGCERRFARSDELSRHRRTHTGEKKFAC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SHPGCGKTYFKSSHLKAHTRTHTGEKPFSCSWKGCERRFARSDELSRHRRTHTGEKKFAC 370 380 390 400 410 420 430 440 450 460 pF1KB4 PMCDRRFMRSDHLTKHARRHLSAKKLPNWQMEVSKLNDIALPPTPAPTQ ::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PMCDRRFMRSDHLTKHARRHLSAKKLPNWQMEVSKLNDIALPPTPAPTQ 430 440 450 460 >>NP_005646 (OMIM: 601878) Krueppel-like factor 10 isofo (480 aa) initn: 3222 init1: 3222 opt: 3222 Z-score: 1291.4 bits: 248.3 E(85289): 3.4e-65 Smith-Waterman score: 3222; 100.0% identity (100.0% similar) in 468 aa overlap (2-469:13-480) 10 20 30 40 pF1KB4 MEERMEMISERPKESMYSWNKTAEKSDFEAVEALMSMSCSWKSDFKKYV :::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MLNFGASLQQTAEERMEMISERPKESMYSWNKTAEKSDFEAVEALMSMSCSWKSDFKKYV 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB4 ENRPVTPVSDLSEEENLLPGTPDFHTIPAFCLTPPYSPSDFEPSQVSNLMAPAPSTVHFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 ENRPVTPVSDLSEEENLLPGTPDFHTIPAFCLTPPYSPSDFEPSQVSNLMAPAPSTVHFK 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB4 SLSDTAKPHIAAPFKEEEKSPVSAPKLPKAQATSVIRHTADAQLCNHQTCPMKAASILNY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 SLSDTAKPHIAAPFKEEEKSPVSAPKLPKAQATSVIRHTADAQLCNHQTCPMKAASILNY 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB4 QNNSFRRRTHLNVEAARKNIPCAAVSPNRSKCERNTVADVDEKASAALYDFSVPSSETVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 QNNSFRRRTHLNVEAARKNIPCAAVSPNRSKCERNTVADVDEKASAALYDFSVPSSETVI 190 200 210 220 230 240 230 240 250 260 270 280 pF1KB4 CRSQPAPVSPQQKSVLVSPPAVSAGGVPPMPVICQMVPLPANNPVVTTVVPSTPPSQPPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 CRSQPAPVSPQQKSVLVSPPAVSAGGVPPMPVICQMVPLPANNPVVTTVVPSTPPSQPPA 250 260 270 280 290 300 290 300 310 320 330 340 pF1KB4 VCPPVVFMGTQVPKGAVMFVVPQPVVQSSKPPVVSPNGTRLSPIAPAPGFSPSAAKVTPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 VCPPVVFMGTQVPKGAVMFVVPQPVVQSSKPPVVSPNGTRLSPIAPAPGFSPSAAKVTPQ 310 320 330 340 350 360 350 360 370 380 390 400 pF1KB4 IDSSRIRSHICSHPGCGKTYFKSSHLKAHTRTHTGEKPFSCSWKGCERRFARSDELSRHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 IDSSRIRSHICSHPGCGKTYFKSSHLKAHTRTHTGEKPFSCSWKGCERRFARSDELSRHR 370 380 390 400 410 420 410 420 430 440 450 460 pF1KB4 RTHTGEKKFACPMCDRRFMRSDHLTKHARRHLSAKKLPNWQMEVSKLNDIALPPTPAPTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 RTHTGEKKFACPMCDRRFMRSDHLTKHARRHLSAKKLPNWQMEVSKLNDIALPPTPAPTQ 430 440 450 460 470 480 >>NP_001171187 (OMIM: 603301,610508) Krueppel-like facto (495 aa) initn: 942 init1: 740 opt: 904 Z-score: 384.7 bits: 80.6 E(85289): 1.1e-14 Smith-Waterman score: 1046; 40.3% identity (61.9% similar) in 494 aa overlap (6-465:5-484) 10 20 30 40 50 pF1KB4 MEERMEMISERPK-ESMYSWNKTAEKSDFEAVEALMSMSCSWKSDFKK--YVENRPVTPV : : :: . .: : . :..:.::::::. :: :: . .: .. ::.::: NP_001 MDICESILERKRHDSERSTCSILEQTDMEAVEALVCMS-SWGQRSQKGDLLRIRPLTPV 10 20 30 40 50 60 70 80 90 100 pF1KB4 SD---LSEEENLLPGTP----DFHTIPAFCLTPPYSPSDFEPSQ---VSNLMAPAPSTVH :: .. .. .:: :::.. ..:.::: ::. ::: :: .. . . . NP_001 SDSGDVTTTVHMDAATPELPKDFHSLSTLCITPPQSPDLVEPSTRTPVSPQVTDSKACTA 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB4 FKSLSDTAKPHIAAPFKEEEK----SPVSAPKLP-KAQATSVIRHTADAQLCNHQTCPMK :...: : :. :: :. : .:..:::::::... : NP_001 TDVLQSSAVVARALSGGAERGLLGLEPV--PSSPCRAKGTSVIRHTGESPAACFPTIQTP 120 130 140 150 160 170 170 180 190 200 210 pF1KB4 AASILNYQNNSFRRRTHLNVEAARKNIPCAAVSPNRSKCE----RNTVADVDEKASAALY . . ... . :... .. . .: : .:. .. . .:.. : . NP_001 DCRLSDSREGEEQLLGHFET-LQDTHLTDSLLSTNLVSCQPCLHKSGGLLLTDKGQQAGW 180 190 200 210 220 230 220 230 240 250 260 270 pF1KB4 DFSVPSSETVICRSQPAPVSPQQKSVLVSPPAVSAGGVPPMPVICQMVP-------LPA- .: . : .: . .. . : .:.. :: ::.:::.: ::: NP_001 PGAVQT-----C----SPKNYENDLPRKTTPLISVS-VPAPPVLCQMIPVTGQSSMLPAF 240 250 260 270 280 280 290 300 310 320 pF1KB4 -NNPVVTTVVPSTPPSQPPAVCPPVVFMGTQVPKGAVMFVVPQPVVQSSKP---PVVSPN . : .: : : : ::.: ::.::::.:.:: .. : :.. . NP_001 LKPPPQLSVGTVRPILAQAAPAPQPVFVGPAVPQGAVMLVLPQGALPPPAPCAANVMAAG 290 300 310 320 330 340 330 340 350 360 370 380 pF1KB4 GTRLSPIAPAPGFSPSAAKVTPQIDSSRIRSHICSHPGCGKTYFKSSHLKAHTRTHTGEK .:.: :.:::: : :. . .::.: :: :...:: ::: :::::::::::: ::::::: NP_001 NTKLLPLAPAPVFITSSQNCVPQVDFSRRRNYVCSFPGCRKTYFKSSHLKAHLRTHTGEK 350 360 370 380 390 400 390 400 410 420 430 440 pF1KB4 PFSCSWKGCERRFARSDELSRHRRTHTGEKKFACPMCDRRFMRSDHLTKHARRHLSAKKL ::.::: ::...::::::::::::::::::::.::.::::::::::::::::::...::. NP_001 PFNCSWDGCDKKFARSDELSRHRRTHTGEKKFVCPVCDRRFMRSDHLTKHARRHMTTKKI 410 420 430 440 450 460 450 460 pF1KB4 PNWQMEVSKLNDIALPPTPAPTQ :.:: ::.::: :: .: NP_001 PGWQAEVGKLNRIASAESPGSPLVSMPASA 470 480 490 >>NP_001171189 (OMIM: 603301,610508) Krueppel-like facto (495 aa) initn: 942 init1: 740 opt: 904 Z-score: 384.7 bits: 80.6 E(85289): 1.1e-14 Smith-Waterman score: 1046; 40.3% identity (61.9% similar) in 494 aa overlap (6-465:5-484) 10 20 30 40 50 pF1KB4 MEERMEMISERPK-ESMYSWNKTAEKSDFEAVEALMSMSCSWKSDFKK--YVENRPVTPV : : :: . .: : . :..:.::::::. :: :: . .: .. ::.::: NP_001 MDICESILERKRHDSERSTCSILEQTDMEAVEALVCMS-SWGQRSQKGDLLRIRPLTPV 10 20 30 40 50 60 70 80 90 100 pF1KB4 SD---LSEEENLLPGTP----DFHTIPAFCLTPPYSPSDFEPSQ---VSNLMAPAPSTVH :: .. .. .:: :::.. ..:.::: ::. ::: :: .. . . . NP_001 SDSGDVTTTVHMDAATPELPKDFHSLSTLCITPPQSPDLVEPSTRTPVSPQVTDSKACTA 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB4 FKSLSDTAKPHIAAPFKEEEK----SPVSAPKLP-KAQATSVIRHTADAQLCNHQTCPMK :...: : :. :: :. : .:..:::::::... : NP_001 TDVLQSSAVVARALSGGAERGLLGLEPV--PSSPCRAKGTSVIRHTGESPAACFPTIQTP 120 130 140 150 160 170 170 180 190 200 210 pF1KB4 AASILNYQNNSFRRRTHLNVEAARKNIPCAAVSPNRSKCE----RNTVADVDEKASAALY . . ... . :... .. . .: : .:. .. . .:.. : . NP_001 DCRLSDSREGEEQLLGHFET-LQDTHLTDSLLSTNLVSCQPCLHKSGGLLLTDKGQQAGW 180 190 200 210 220 230 220 230 240 250 260 270 pF1KB4 DFSVPSSETVICRSQPAPVSPQQKSVLVSPPAVSAGGVPPMPVICQMVP-------LPA- .: . : .: . .. . : .:.. :: ::.:::.: ::: NP_001 PGAVQT-----C----SPKNYENDLPRKTTPLISVS-VPAPPVLCQMIPVTGQSSMLPAF 240 250 260 270 280 280 290 300 310 320 pF1KB4 -NNPVVTTVVPSTPPSQPPAVCPPVVFMGTQVPKGAVMFVVPQPVVQSSKP---PVVSPN . : .: : : : ::.: ::.::::.:.:: .. : :.. . NP_001 LKPPPQLSVGTVRPILAQAAPAPQPVFVGPAVPQGAVMLVLPQGALPPPAPCAANVMAAG 290 300 310 320 330 340 330 340 350 360 370 380 pF1KB4 GTRLSPIAPAPGFSPSAAKVTPQIDSSRIRSHICSHPGCGKTYFKSSHLKAHTRTHTGEK .:.: :.:::: : :. . .::.: :: :...:: ::: :::::::::::: ::::::: NP_001 NTKLLPLAPAPVFITSSQNCVPQVDFSRRRNYVCSFPGCRKTYFKSSHLKAHLRTHTGEK 350 360 370 380 390 400 390 400 410 420 430 440 pF1KB4 PFSCSWKGCERRFARSDELSRHRRTHTGEKKFACPMCDRRFMRSDHLTKHARRHLSAKKL ::.::: ::...::::::::::::::::::::.::.::::::::::::::::::...::. NP_001 PFNCSWDGCDKKFARSDELSRHRRTHTGEKKFVCPVCDRRFMRSDHLTKHARRHMTTKKI 410 420 430 440 450 460 450 460 pF1KB4 PNWQMEVSKLNDIALPPTPAPTQ :.:: ::.::: :: .: NP_001 PGWQAEVGKLNRIASAESPGSPLVSMPASA 470 480 490 >>NP_003588 (OMIM: 603301,610508) Krueppel-like factor 1 (512 aa) initn: 942 init1: 740 opt: 904 Z-score: 384.6 bits: 80.6 E(85289): 1.1e-14 Smith-Waterman score: 1046; 40.3% identity (61.9% similar) in 494 aa overlap (6-465:22-501) 10 20 30 40 pF1KB4 MEERMEMISERPK-ESMYSWNKTAEKSDFEAVEALMSMSCSWKS : : :: . .: : . :..:.::::::. :: :: . NP_003 MHTPDFAGPDDARAVDIMDICESILERKRHDSERSTCSILEQTDMEAVEALVCMS-SWGQ 10 20 30 40 50 50 60 70 80 90 pF1KB4 DFKK--YVENRPVTPVSD---LSEEENLLPGTP----DFHTIPAFCLTPPYSPSDFEPSQ .: .. ::.::::: .. .. .:: :::.. ..:.::: ::. ::: NP_003 RSQKGDLLRIRPLTPVSDSGDVTTTVHMDAATPELPKDFHSLSTLCITPPQSPDLVEPST 60 70 80 90 100 110 100 110 120 130 140 pF1KB4 ---VSNLMAPAPSTVHFKSLSDTAKPHIAAPFKEEEK----SPVSAPKLP-KAQATSVIR :: .. . . . :...: : :. :: :. : .:..::::: NP_003 RTPVSPQVTDSKACTATDVLQSSAVVARALSGGAERGLLGLEPV--PSSPCRAKGTSVIR 120 130 140 150 160 170 150 160 170 180 190 200 pF1KB4 HTADAQLCNHQTCPMKAASILNYQNNSFRRRTHLNVEAARKNIPCAAVSPNRSKCE---- ::... : . . ... . :... .. . .: : .:. NP_003 HTGESPAACFPTIQTPDCRLSDSREGEEQLLGHFET-LQDTHLTDSLLSTNLVSCQPCLH 180 190 200 210 220 230 210 220 230 240 250 260 pF1KB4 RNTVADVDEKASAALYDFSVPSSETVICRSQPAPVSPQQKSVLVSPPAVSAGGVPPMPVI .. . .:.. : . .: . : .: . .. . : .:.. :: ::. NP_003 KSGGLLLTDKGQQAGWPGAVQT-----C----SPKNYENDLPRKTTPLISVS-VPAPPVL 240 250 260 270 280 270 280 290 300 310 pF1KB4 CQMVP-------LPA--NNPVVTTVVPSTPPSQPPAVCPPVVFMGTQVPKGAVMFVVPQP :::.: ::: . : .: : : : ::.: ::.::::.:.:: NP_003 CQMIPVTGQSSMLPAFLKPPPQLSVGTVRPILAQAAPAPQPVFVGPAVPQGAVMLVLPQG 290 300 310 320 330 340 320 330 340 350 360 370 pF1KB4 VVQSSKP---PVVSPNGTRLSPIAPAPGFSPSAAKVTPQIDSSRIRSHICSHPGCGKTYF .. : :.. ..:.: :.:::: : :. . .::.: :: :...:: ::: :::: NP_003 ALPPPAPCAANVMAAGNTKLLPLAPAPVFITSSQNCVPQVDFSRRRNYVCSFPGCRKTYF 350 360 370 380 390 400 380 390 400 410 420 430 pF1KB4 KSSHLKAHTRTHTGEKPFSCSWKGCERRFARSDELSRHRRTHTGEKKFACPMCDRRFMRS :::::::: :::::::::.::: ::...::::::::::::::::::::.::.:::::::: NP_003 KSSHLKAHLRTHTGEKPFNCSWDGCDKKFARSDELSRHRRTHTGEKKFVCPVCDRRFMRS 410 420 430 440 450 460 440 450 460 pF1KB4 DHLTKHARRHLSAKKLPNWQMEVSKLNDIALPPTPAPTQ ::::::::::...::.:.:: ::.::: :: .: NP_003 DHLTKHARRHMTTKKIPGWQAEVGKLNRIASAESPGSPLVSMPASA 470 480 490 500 510 >>NP_114124 (OMIM: 606139) Krueppel-like factor 16 [Homo (252 aa) initn: 512 init1: 512 opt: 542 Z-score: 246.3 bits: 54.0 E(85289): 5.5e-07 Smith-Waterman score: 542; 47.2% identity (73.6% similar) in 163 aa overlap (280-440:53-209) 250 260 270 280 290 300 pF1KB4 AVSAGGVPPMPVICQMVPLPANNPVVTTVVPSTPPSQPPAVCPPVVFMGTQVPKGAVMFV :.:: :: ::.. : .:. . NP_114 AVVHRGRPGPEGAGPAAGLDVRAARREAASPGTPGPPPP---PPAA-SGPGPGAAAAPHL 30 40 50 60 70 310 320 330 340 350 360 pF1KB4 VPQPVVQSSKP-PVVSPNGTRLSPIAPAPGFS-PSAAKVTPQIDSSRIRSHICSHPGCGK . .. . . : ..:.:. :: . . . : ::.... :. .:: : : :.: NP_114 LAASILADLRGGPGAAPGGA--SPASSSSAASSPSSGRAPGAAPSAAAKSHRCPFPDCAK 80 90 100 110 120 130 370 380 390 400 410 420 pF1KB4 TYFKSSHLKAHTRTHTGEKPFSCSWKGCERRFARSDELSRHRRTHTGEKKFACPMCDRRF .:.::::::.: ::::::.::.:.:.::...:::::::.::.:::::::.:.::.:..:: NP_114 AYYKSSHLKSHLRTHTGERPFACDWQGCDKKFARSDELARHHRTHTGEKRFSCPLCSKRF 140 150 160 170 180 190 430 440 450 460 pF1KB4 MRSDHLTKHARRHLSAKKLPNWQMEVSKLNDIALPPTPAPTQ :::::.:::::: NP_114 TRSDHLAKHARRHPGFHPDLLRRPGARSTSPSDSLPCSLAGSPAPSPAPSPAPAGL 200 210 220 230 240 250 >>NP_057079 (OMIM: 605328,612001) Krueppel-like factor 1 (288 aa) initn: 518 init1: 495 opt: 520 Z-score: 237.1 bits: 52.5 E(85289): 1.8e-06 Smith-Waterman score: 521; 37.4% identity (57.6% similar) in 257 aa overlap (185-440:33-249) 160 170 180 190 200 210 pF1KB4 NHQTCPMKAASILNYQNNSFRRRTHLNVEAARKNIPCAAVSPNRSKCERNTVADVDEKAS .: . .:..:. . :. : : : NP_057 AAAYVDHFAAECLVSMSSRAVVHGPREGPESRPEGAAVAATPTLPRVEERR----DGKDS 10 20 30 40 50 220 230 240 250 260 270 pF1KB4 AALYDFSVPSSETVICRSQPAPVSPQQKSVLVSPPAVSAGGVPPMPVICQMVPLPANNPV :.: : : . . .. :::. ... .. : . .:: : : NP_057 ASL--FVVARILADLNQQAPAPAPAERREGAAARKARTPCRLPP--------PAPE---- 60 70 80 90 100 280 290 300 310 320 330 pF1KB4 VTTVVPSTPPSQPPAVCPPVVFMGTQVPKGAVMFVVPQPVVQSSKPPVVSPNGTRLSPIA :..: .. :. :: . :. :. .. . : .: :. NP_057 -----PTSPGAEGAAAAPPSPAWSE--PE-------PEAGLEPEREP--GPAGS------ 110 120 130 140 340 350 360 370 380 390 pF1KB4 PAPGFSPSAAKVTPQID-SSRIRSHICSHPGCGKTYFKSSHLKAHTRTHTGEKPFSCSWK ::. . . . : : :.: : . :: :.: :::::::: ::::::.::.:::. NP_057 GEPGLRQRVRRGRSRADLESPQRKHKCHYAGCEKVYGKSSHLKAHLRTHTGERPFACSWQ 150 160 170 180 190 200 400 410 420 430 440 450 pF1KB4 GCERRFARSDELSRHRRTHTGEKKFACPMCDRRFMRSDHLTKHARRHLSAKKLPNWQMEV :...:::::::.:: :::::::::.::.:..::::::::::::::: NP_057 DCNKKFARSDELARHYRTHTGEKKFSCPICEKRFMRSDHLTKHARRHANFHPGMLQRRGG 210 220 230 240 250 260 460 pF1KB4 SKLNDIALPPTPAPTQ NP_057 GSRTGSLSDYSRSDASSPTISPASSP 270 280 >>XP_005247457 (OMIM: 606465) PREDICTED: Krueppel-like f (416 aa) initn: 586 init1: 421 opt: 520 Z-score: 235.4 bits: 52.7 E(85289): 2.3e-06 Smith-Waterman score: 530; 39.1% identity (63.0% similar) in 230 aa overlap (231-440:179-403) 210 220 230 240 250 pF1KB4 CERNTVADVDEKASAALYDFSVPSSETVICRSQPAPVSPQQKSVLVSPPAVSAGGV--P- .:. : : .. : ..::::. : XP_005 EENMEPGVKEVPEGNSKDLDACSQLSAGPHKSHLHPGSSGRERCSPPPGGASAGGAQGPG 150 160 170 180 190 200 260 270 280 290 300 310 pF1KB4 -------PMPVICQMVPLPANNPVVTTVVPSTPPSQPPAVCPPVVFMGTQVPKGAVMFVV :.::. :. :.:... : :..: . : : .... : : .. .: XP_005 GGPTPDGPIPVLLQIQPVPVKQESGTG--PASPGQAPENVKVAQLLVNIQ---GQTFALV 210 220 230 240 250 260 320 330 340 350 360 pF1KB4 PQPVVQS-----SKPPVVSPNGTRLSPIAPAP-GFSPSA---AKVTPQIDSSR-IRSHIC :: : .: :: ..: .:.. .: : .:.. .. :. ... :. : : XP_005 PQVVPSSNLNLPSKFVRIAPVPIAAKPVGSGPLGPGPAGLLMGQKFPKNPAAELIKMHKC 270 280 290 300 310 320 370 380 390 400 410 420 pF1KB4 SHPGCGKTYFKSSHLKAHTRTHTGEKPFSCSWKGCERRFARSDELSRHRRTHTGEKKFAC . :::.: : :::::::: : :::::::.:.: :: ::.::::::::::.:.: : . : XP_005 TFPGCSKMYTKSSHLKAHLRRHTGEKPFACTWPGCGWRFSRSDELSRHRRSHSGVKPYQC 330 340 350 360 370 380 430 440 450 460 pF1KB4 PMCDRRFMRSDHLTKHARRHLSAKKLPNWQMEVSKLNDIALPPTPAPTQ :.:...: :::::.:: . : XP_005 PVCEKKFARSDHLSKHIKVHRFPRSSRSVRSVN 390 400 410 >>NP_054798 (OMIM: 606465) Krueppel-like factor 15 [Homo (416 aa) initn: 586 init1: 421 opt: 520 Z-score: 235.4 bits: 52.7 E(85289): 2.3e-06 Smith-Waterman score: 530; 39.1% identity (63.0% similar) in 230 aa overlap (231-440:179-403) 210 220 230 240 250 pF1KB4 CERNTVADVDEKASAALYDFSVPSSETVICRSQPAPVSPQQKSVLVSPPAVSAGGV--P- .:. : : .. : ..::::. : NP_054 EENMEPGVKEVPEGNSKDLDACSQLSAGPHKSHLHPGSSGRERCSPPPGGASAGGAQGPG 150 160 170 180 190 200 260 270 280 290 300 310 pF1KB4 -------PMPVICQMVPLPANNPVVTTVVPSTPPSQPPAVCPPVVFMGTQVPKGAVMFVV :.::. :. :.:... : :..: . : : .... : : .. .: NP_054 GGPTPDGPIPVLLQIQPVPVKQESGTG--PASPGQAPENVKVAQLLVNIQ---GQTFALV 210 220 230 240 250 260 320 330 340 350 360 pF1KB4 PQPVVQS-----SKPPVVSPNGTRLSPIAPAP-GFSPSA---AKVTPQIDSSR-IRSHIC :: : .: :: ..: .:.. .: : .:.. .. :. ... :. : : NP_054 PQVVPSSNLNLPSKFVRIAPVPIAAKPVGSGPLGPGPAGLLMGQKFPKNPAAELIKMHKC 270 280 290 300 310 320 370 380 390 400 410 420 pF1KB4 SHPGCGKTYFKSSHLKAHTRTHTGEKPFSCSWKGCERRFARSDELSRHRRTHTGEKKFAC . :::.: : :::::::: : :::::::.:.: :: ::.::::::::::.:.: : . : NP_054 TFPGCSKMYTKSSHLKAHLRRHTGEKPFACTWPGCGWRFSRSDELSRHRRSHSGVKPYQC 330 340 350 360 370 380 430 440 450 460 pF1KB4 PMCDRRFMRSDHLTKHARRHLSAKKLPNWQMEVSKLNDIALPPTPAPTQ :.:...: :::::.:: . : NP_054 PVCEKKFARSDHLSKHIKVHRFPRSSRSVRSVN 390 400 410 >>XP_011511045 (OMIM: 606465) PREDICTED: Krueppel-like f (435 aa) initn: 586 init1: 421 opt: 520 Z-score: 235.2 bits: 52.7 E(85289): 2.3e-06 Smith-Waterman score: 530; 39.1% identity (63.0% similar) in 230 aa overlap (231-440:198-422) 210 220 230 240 250 pF1KB4 CERNTVADVDEKASAALYDFSVPSSETVICRSQPAPVSPQQKSVLVSPPAVSAGGV--P- .:. : : .. : ..::::. : XP_011 EENMEPGVKEVPEGNSKDLDACSQLSAGPHKSHLHPGSSGRERCSPPPGGASAGGAQGPG 170 180 190 200 210 220 260 270 280 290 300 310 pF1KB4 -------PMPVICQMVPLPANNPVVTTVVPSTPPSQPPAVCPPVVFMGTQVPKGAVMFVV :.::. :. :.:... : :..: . : : .... : : .. .: XP_011 GGPTPDGPIPVLLQIQPVPVKQESGTG--PASPGQAPENVKVAQLLVNIQ---GQTFALV 230 240 250 260 270 280 320 330 340 350 360 pF1KB4 PQPVVQS-----SKPPVVSPNGTRLSPIAPAP-GFSPSA---AKVTPQIDSSR-IRSHIC :: : .: :: ..: .:.. .: : .:.. .. :. ... :. : : XP_011 PQVVPSSNLNLPSKFVRIAPVPIAAKPVGSGPLGPGPAGLLMGQKFPKNPAAELIKMHKC 290 300 310 320 330 340 370 380 390 400 410 420 pF1KB4 SHPGCGKTYFKSSHLKAHTRTHTGEKPFSCSWKGCERRFARSDELSRHRRTHTGEKKFAC . :::.: : :::::::: : :::::::.:.: :: ::.::::::::::.:.: : . : XP_011 TFPGCSKMYTKSSHLKAHLRRHTGEKPFACTWPGCGWRFSRSDELSRHRRSHSGVKPYQC 350 360 370 380 390 400 430 440 450 460 pF1KB4 PMCDRRFMRSDHLTKHARRHLSAKKLPNWQMEVSKLNDIALPPTPAPTQ :.:...: :::::.:: . : XP_011 PVCEKKFARSDHLSKHIKVHRFPRSSRSVRSVN 410 420 430 469 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 14:12:39 2016 done: Thu Nov 3 14:12:40 2016 Total Scan time: 11.420 Total Display time: 0.060 Function used was FASTA [36.3.4 Apr, 2011]