FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB4020, 664 aa
1>>>pF1KB4020 664 - 664 aa - 664 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.6897+/-0.00125; mu= -4.7276+/- 0.074
mean_var=395.8649+/-82.310, 0's: 0 Z-trim(111.1): 166 B-trim: 0 in 0/53
Lambda= 0.064462
statistics sampled from 11961 (12118) to 11961 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.7), E-opt: 0.2 (0.372), width: 16
Scan time: 3.150
The best scores are: opt bits E(32554)
CCDS1129.1 LMNA gene_id:4000|Hs108|chr1 ( 664) 4212 406.7 5.4e-113
CCDS72941.1 LMNA gene_id:4000|Hs108|chr1 ( 614) 3837 371.8 1.6e-102
CCDS1131.1 LMNA gene_id:4000|Hs108|chr1 ( 572) 3560 346.0 8.7e-95
CCDS58038.1 LMNA gene_id:4000|Hs108|chr1 ( 574) 3489 339.4 8.4e-93
CCDS72942.1 LMNA gene_id:4000|Hs108|chr1 ( 491) 2843 279.2 9.2e-75
CCDS4140.1 LMNB1 gene_id:4001|Hs108|chr5 ( 586) 2020 202.8 1.1e-51
CCDS12090.2 LMNB2 gene_id:84823|Hs108|chr19 ( 620) 1513 155.7 1.9e-37
>>CCDS1129.1 LMNA gene_id:4000|Hs108|chr1 (664 aa)
initn: 4212 init1: 4212 opt: 4212 Z-score: 2142.1 bits: 406.7 E(32554): 5.4e-113
Smith-Waterman score: 4212; 100.0% identity (100.0% similar) in 664 aa overlap (1-664:1-664)
10 20 30 40 50 60
pF1KB4 METPSQRRATRSGAQASSTPLSPTRITRLQEKEDLQELNDRLAVYIDRVRSLETENAGLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 METPSQRRATRSGAQASSTPLSPTRITRLQEKEDLQELNDRLAVYIDRVRSLETENAGLR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 LRITESEEVVSREVSGIKAAYEAELGDARKTLDSVAKERARLQLELSKVREEFKELKARN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 LRITESEEVVSREVSGIKAAYEAELGDARKTLDSVAKERARLQLELSKVREEFKELKARN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 TKKEGDLIAAQARLKDLEALLNSKEAALSTALSEKRTLEGELHDLRGQVAKLEAALGEAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 TKKEGDLIAAQARLKDLEALLNSKEAALSTALSEKRTLEGELHDLRGQVAKLEAALGEAK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 KQLQDEMLRRVDAENRLQTMKEELDFQKNIYSEELRETKRRHETRLVEIDNGKQREFESR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 KQLQDEMLRRVDAENRLQTMKEELDFQKNIYSEELRETKRRHETRLVEIDNGKQREFESR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 LADALQELRAQHEDQVEQYKKELEKTYSAKLDNARQSAERNSNLVGAAHEELQQSRIRID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 LADALQELRAQHEDQVEQYKKELEKTYSAKLDNARQSAERNSNLVGAAHEELQQSRIRID
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 SLSAQLSQLQKQLAAKEAKLRDLEDSLARERDTSRRLLAEKEREMAEMRARMQQQLDEYQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 SLSAQLSQLQKQLAAKEAKLRDLEDSLARERDTSRRLLAEKEREMAEMRARMQQQLDEYQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 ELLDIKLALDMEIHAYRKLLEGEEERLRLSPSPTSQRSRGRASSHSSQTQGGGSVTKKRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 ELLDIKLALDMEIHAYRKLLEGEEERLRLSPSPTSQRSRGRASSHSSQTQGGGSVTKKRK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 LESTESRSSFSQHARTSGRVAVEEVDEEGKFVRLRNKSNEDQSMGNWQIKRQNGDDPLLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 LESTESRSSFSQHARTSGRVAVEEVDEEGKFVRLRNKSNEDQSMGNWQIKRQNGDDPLLT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 YRFPPKFTLKAGQVVTIWAAGAGATHSPPTDLVWKAQNTWGCGNSLRTALINSTGEEVAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 YRFPPKFTLKAGQVVTIWAAGAGATHSPPTDLVWKAQNTWGCGNSLRTALINSTGEEVAM
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB4 RKLVRSVTVVEDDEDEDGDDLLHHHHGSHCSSSGDPAEYNLRSRTVLCGTCGQPADKASA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 RKLVRSVTVVEDDEDEDGDDLLHHHHGSHCSSSGDPAEYNLRSRTVLCGTCGQPADKASA
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB4 SGSGAQVGGPISSGSSASSVTVTRSYRSVGGSGGGSFGDNLVTRSYLLGNSSPRTQSPQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 SGSGAQVGGPISSGSSASSVTVTRSYRSVGGSGGGSFGDNLVTRSYLLGNSSPRTQSPQN
610 620 630 640 650 660
pF1KB4 CSIM
::::
CCDS11 CSIM
>>CCDS72941.1 LMNA gene_id:4000|Hs108|chr1 (614 aa)
initn: 3837 init1: 3837 opt: 3837 Z-score: 1954.1 bits: 371.8 E(32554): 1.6e-102
Smith-Waterman score: 3837; 100.0% identity (100.0% similar) in 606 aa overlap (1-606:1-606)
10 20 30 40 50 60
pF1KB4 METPSQRRATRSGAQASSTPLSPTRITRLQEKEDLQELNDRLAVYIDRVRSLETENAGLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 METPSQRRATRSGAQASSTPLSPTRITRLQEKEDLQELNDRLAVYIDRVRSLETENAGLR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 LRITESEEVVSREVSGIKAAYEAELGDARKTLDSVAKERARLQLELSKVREEFKELKARN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 LRITESEEVVSREVSGIKAAYEAELGDARKTLDSVAKERARLQLELSKVREEFKELKARN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 TKKEGDLIAAQARLKDLEALLNSKEAALSTALSEKRTLEGELHDLRGQVAKLEAALGEAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 TKKEGDLIAAQARLKDLEALLNSKEAALSTALSEKRTLEGELHDLRGQVAKLEAALGEAK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 KQLQDEMLRRVDAENRLQTMKEELDFQKNIYSEELRETKRRHETRLVEIDNGKQREFESR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 KQLQDEMLRRVDAENRLQTMKEELDFQKNIYSEELRETKRRHETRLVEIDNGKQREFESR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 LADALQELRAQHEDQVEQYKKELEKTYSAKLDNARQSAERNSNLVGAAHEELQQSRIRID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 LADALQELRAQHEDQVEQYKKELEKTYSAKLDNARQSAERNSNLVGAAHEELQQSRIRID
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 SLSAQLSQLQKQLAAKEAKLRDLEDSLARERDTSRRLLAEKEREMAEMRARMQQQLDEYQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 SLSAQLSQLQKQLAAKEAKLRDLEDSLARERDTSRRLLAEKEREMAEMRARMQQQLDEYQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 ELLDIKLALDMEIHAYRKLLEGEEERLRLSPSPTSQRSRGRASSHSSQTQGGGSVTKKRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 ELLDIKLALDMEIHAYRKLLEGEEERLRLSPSPTSQRSRGRASSHSSQTQGGGSVTKKRK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 LESTESRSSFSQHARTSGRVAVEEVDEEGKFVRLRNKSNEDQSMGNWQIKRQNGDDPLLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 LESTESRSSFSQHARTSGRVAVEEVDEEGKFVRLRNKSNEDQSMGNWQIKRQNGDDPLLT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 YRFPPKFTLKAGQVVTIWAAGAGATHSPPTDLVWKAQNTWGCGNSLRTALINSTGEEVAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 YRFPPKFTLKAGQVVTIWAAGAGATHSPPTDLVWKAQNTWGCGNSLRTALINSTGEEVAM
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB4 RKLVRSVTVVEDDEDEDGDDLLHHHHGSHCSSSGDPAEYNLRSRTVLCGTCGQPADKASA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 RKLVRSVTVVEDDEDEDGDDLLHHHHGSHCSSSGDPAEYNLRSRTVLCGTCGQPADKASA
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB4 SGSGAQVGGPISSGSSASSVTVTRSYRSVGGSGGGSFGDNLVTRSYLLGNSSPRTQSPQN
::::::
CCDS72 SGSGAQSPQNCSIM
610
>>CCDS1131.1 LMNA gene_id:4000|Hs108|chr1 (572 aa)
initn: 3601 init1: 3560 opt: 3560 Z-score: 1815.2 bits: 346.0 E(32554): 8.7e-95
Smith-Waterman score: 3560; 99.8% identity (99.8% similar) in 568 aa overlap (1-568:1-568)
10 20 30 40 50 60
pF1KB4 METPSQRRATRSGAQASSTPLSPTRITRLQEKEDLQELNDRLAVYIDRVRSLETENAGLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 METPSQRRATRSGAQASSTPLSPTRITRLQEKEDLQELNDRLAVYIDRVRSLETENAGLR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 LRITESEEVVSREVSGIKAAYEAELGDARKTLDSVAKERARLQLELSKVREEFKELKARN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 LRITESEEVVSREVSGIKAAYEAELGDARKTLDSVAKERARLQLELSKVREEFKELKARN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 TKKEGDLIAAQARLKDLEALLNSKEAALSTALSEKRTLEGELHDLRGQVAKLEAALGEAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 TKKEGDLIAAQARLKDLEALLNSKEAALSTALSEKRTLEGELHDLRGQVAKLEAALGEAK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 KQLQDEMLRRVDAENRLQTMKEELDFQKNIYSEELRETKRRHETRLVEIDNGKQREFESR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 KQLQDEMLRRVDAENRLQTMKEELDFQKNIYSEELRETKRRHETRLVEIDNGKQREFESR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 LADALQELRAQHEDQVEQYKKELEKTYSAKLDNARQSAERNSNLVGAAHEELQQSRIRID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 LADALQELRAQHEDQVEQYKKELEKTYSAKLDNARQSAERNSNLVGAAHEELQQSRIRID
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 SLSAQLSQLQKQLAAKEAKLRDLEDSLARERDTSRRLLAEKEREMAEMRARMQQQLDEYQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 SLSAQLSQLQKQLAAKEAKLRDLEDSLARERDTSRRLLAEKEREMAEMRARMQQQLDEYQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 ELLDIKLALDMEIHAYRKLLEGEEERLRLSPSPTSQRSRGRASSHSSQTQGGGSVTKKRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 ELLDIKLALDMEIHAYRKLLEGEEERLRLSPSPTSQRSRGRASSHSSQTQGGGSVTKKRK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 LESTESRSSFSQHARTSGRVAVEEVDEEGKFVRLRNKSNEDQSMGNWQIKRQNGDDPLLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 LESTESRSSFSQHARTSGRVAVEEVDEEGKFVRLRNKSNEDQSMGNWQIKRQNGDDPLLT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 YRFPPKFTLKAGQVVTIWAAGAGATHSPPTDLVWKAQNTWGCGNSLRTALINSTGEEVAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 YRFPPKFTLKAGQVVTIWAAGAGATHSPPTDLVWKAQNTWGCGNSLRTALINSTGEEVAM
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB4 RKLVRSVTVVEDDEDEDGDDLLHHHHGSHCSSSGDPAEYNLRSRTVLCGTCGQPADKASA
:::::::::::::::::::::::::: :
CCDS11 RKLVRSVTVVEDDEDEDGDDLLHHHHVSGSRR
550 560 570
>>CCDS58038.1 LMNA gene_id:4000|Hs108|chr1 (574 aa)
initn: 3631 init1: 3489 opt: 3489 Z-score: 1779.5 bits: 339.4 E(32554): 8.4e-93
Smith-Waterman score: 3489; 99.8% identity (100.0% similar) in 545 aa overlap (120-664:8-552)
90 100 110 120 130 140
pF1KB4 KTLDSVAKERARLQLELSKVREEFKELKARNTKKEGDLIAAQARLKDLEALLNSKEAALS
::::::::::::::::::::::::::::::
CCDS58 MGNSEGCNTKKEGDLIAAQARLKDLEALLNSKEAALS
10 20 30
150 160 170 180 190 200
pF1KB4 TALSEKRTLEGELHDLRGQVAKLEAALGEAKKQLQDEMLRRVDAENRLQTMKEELDFQKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 TALSEKRTLEGELHDLRGQVAKLEAALGEAKKQLQDEMLRRVDAENRLQTMKEELDFQKN
40 50 60 70 80 90
210 220 230 240 250 260
pF1KB4 IYSEELRETKRRHETRLVEIDNGKQREFESRLADALQELRAQHEDQVEQYKKELEKTYSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 IYSEELRETKRRHETRLVEIDNGKQREFESRLADALQELRAQHEDQVEQYKKELEKTYSA
100 110 120 130 140 150
270 280 290 300 310 320
pF1KB4 KLDNARQSAERNSNLVGAAHEELQQSRIRIDSLSAQLSQLQKQLAAKEAKLRDLEDSLAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 KLDNARQSAERNSNLVGAAHEELQQSRIRIDSLSAQLSQLQKQLAAKEAKLRDLEDSLAR
160 170 180 190 200 210
330 340 350 360 370 380
pF1KB4 ERDTSRRLLAEKEREMAEMRARMQQQLDEYQELLDIKLALDMEIHAYRKLLEGEEERLRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 ERDTSRRLLAEKEREMAEMRARMQQQLDEYQELLDIKLALDMEIHAYRKLLEGEEERLRL
220 230 240 250 260 270
390 400 410 420 430 440
pF1KB4 SPSPTSQRSRGRASSHSSQTQGGGSVTKKRKLESTESRSSFSQHARTSGRVAVEEVDEEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 SPSPTSQRSRGRASSHSSQTQGGGSVTKKRKLESTESRSSFSQHARTSGRVAVEEVDEEG
280 290 300 310 320 330
450 460 470 480 490 500
pF1KB4 KFVRLRNKSNEDQSMGNWQIKRQNGDDPLLTYRFPPKFTLKAGQVVTIWAAGAGATHSPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 KFVRLRNKSNEDQSMGNWQIKRQNGDDPLLTYRFPPKFTLKAGQVVTIWAAGAGATHSPP
340 350 360 370 380 390
510 520 530 540 550 560
pF1KB4 TDLVWKAQNTWGCGNSLRTALINSTGEEVAMRKLVRSVTVVEDDEDEDGDDLLHHHHGSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 TDLVWKAQNTWGCGNSLRTALINSTGEEVAMRKLVRSVTVVEDDEDEDGDDLLHHHHGSH
400 410 420 430 440 450
570 580 590 600 610 620
pF1KB4 CSSSGDPAEYNLRSRTVLCGTCGQPADKASASGSGAQVGGPISSGSSASSVTVTRSYRSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 CSSSGDPAEYNLRSRTVLCGTCGQPADKASASGSGAQVGGPISSGSSASSVTVTRSYRSV
460 470 480 490 500 510
630 640 650 660
pF1KB4 GGSGGGSFGDNLVTRSYLLGNSSPRTQSPQNCSIM
::::::::::::::::::::::::::::::::::.
CCDS58 GGSGGGSFGDNLVTRSYLLGNSSPRTQSPQNCSIIQEMGMRWEVEEGRRKVSLSCLP
520 530 540 550 560 570
>>CCDS72942.1 LMNA gene_id:4000|Hs108|chr1 (491 aa)
initn: 2883 init1: 2842 opt: 2843 Z-score: 1455.7 bits: 279.2 E(32554): 9.2e-75
Smith-Waterman score: 2843; 95.6% identity (96.6% similar) in 475 aa overlap (96-568:13-487)
70 80 90 100 110 120
pF1KB4 SEEVVSREVSGIKAAYEAELGDARKTLDSVAKERARLQLELSKV--REEFKELKARNTKK
:.::. : . : . : . ::::
CCDS72 MQPLLCLGNLEDARERTGTLLAQHPAWGRTRAKPGSPLNTKK
10 20 30 40
130 140 150 160 170 180
pF1KB4 EGDLIAAQARLKDLEALLNSKEAALSTALSEKRTLEGELHDLRGQVAKLEAALGEAKKQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 EGDLIAAQARLKDLEALLNSKEAALSTALSEKRTLEGELHDLRGQVAKLEAALGEAKKQL
50 60 70 80 90 100
190 200 210 220 230 240
pF1KB4 QDEMLRRVDAENRLQTMKEELDFQKNIYSEELRETKRRHETRLVEIDNGKQREFESRLAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 QDEMLRRVDAENRLQTMKEELDFQKNIYSEELRETKRRHETRLVEIDNGKQREFESRLAD
110 120 130 140 150 160
250 260 270 280 290 300
pF1KB4 ALQELRAQHEDQVEQYKKELEKTYSAKLDNARQSAERNSNLVGAAHEELQQSRIRIDSLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 ALQELRAQHEDQVEQYKKELEKTYSAKLDNARQSAERNSNLVGAAHEELQQSRIRIDSLS
170 180 190 200 210 220
310 320 330 340 350 360
pF1KB4 AQLSQLQKQLAAKEAKLRDLEDSLARERDTSRRLLAEKEREMAEMRARMQQQLDEYQELL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 AQLSQLQKQLAAKEAKLRDLEDSLARERDTSRRLLAEKEREMAEMRARMQQQLDEYQELL
230 240 250 260 270 280
370 380 390 400 410 420
pF1KB4 DIKLALDMEIHAYRKLLEGEEERLRLSPSPTSQRSRGRASSHSSQTQGGGSVTKKRKLES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 DIKLALDMEIHAYRKLLEGEEERLRLSPSPTSQRSRGRASSHSSQTQGGGSVTKKRKLES
290 300 310 320 330 340
430 440 450 460 470 480
pF1KB4 TESRSSFSQHARTSGRVAVEEVDEEGKFVRLRNKSNEDQSMGNWQIKRQNGDDPLLTYRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 TESRSSFSQHARTSGRVAVEEVDEEGKFVRLRNKSNEDQSMGNWQIKRQNGDDPLLTYRF
350 360 370 380 390 400
490 500 510 520 530 540
pF1KB4 PPKFTLKAGQVVTIWAAGAGATHSPPTDLVWKAQNTWGCGNSLRTALINSTGEEVAMRKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 PPKFTLKAGQVVTIWAAGAGATHSPPTDLVWKAQNTWGCGNSLRTALINSTGEEVAMRKL
410 420 430 440 450 460
550 560 570 580 590 600
pF1KB4 VRSVTVVEDDEDEDGDDLLHHHHGSHCSSSGDPAEYNLRSRTVLCGTCGQPADKASASGS
::::::::::::::::::::::: :
CCDS72 VRSVTVVEDDEDEDGDDLLHHHHVSGSRR
470 480 490
>>CCDS4140.1 LMNB1 gene_id:4001|Hs108|chr5 (586 aa)
initn: 2045 init1: 1813 opt: 2020 Z-score: 1041.1 bits: 202.8 E(32554): 1.1e-51
Smith-Waterman score: 2020; 55.0% identity (82.9% similar) in 580 aa overlap (3-573:5-580)
10 20 30 40 50
pF1KB4 METP-SQRRATRSGAQASSTPLSPTRITRLQEKEDLQELNDRLAVYIDRVRSLETENA
:: : ..:.:. .:::::::..::::::.:.:::::::::::.::::::::.
CCDS41 MATATPVPPRMGSRAGG--PTTPLSPTRLSRLQEKEELRELNDRLAVYIDKVRSLETENS
10 20 30 40 50
60 70 80 90 100 110
pF1KB4 GLRLRITESEEVVSREVSGIKAAYEAELGDARKTLDSVAKERARLQLELSKVREEFKELK
.:.:..:: ::: .::..:.:: ::.::.:::..::..:.:::.::.::.: . : .:
CCDS41 ALQLQVTEREEVRGRELTGLKALYETELADARRALDDTARERAKLQIELGKCKAEHDQLL
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB4 ARNTKKEGDLIAAQARLKDLEALLNSKEAALSTALSEKRTLEGELHDLRGQVAKLEAALG
.:::.:: .:: .:.. :: ::::.:::.:::..:..:::.:.::. :.:.:::.:.
CCDS41 LNYAKKESDLNGAQIKLREYEAALNSKDAALATALGDKKSLEGDLEDLKDQIAQLEASLA
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB4 EAKKQLQDEMLRRVDAENRLQTMKEELDFQKNIYSEELRETKRRHETRLVEIDNGKQREF
::::: :: : .:: ::: :.. :.:.:.:..: ::. ::.:.:::::::.:.:.: :.
CCDS41 AAKKQLADETLLKVDLENRCQSLTEDLEFRKSMYEEEINETRRKHETRLVEVDSGRQIEY
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB4 ESRLADALQELRAQHEDQVEQYKKELEKTYSAKLDNARQSAERNSNLVGAAHEELQQSRI
: .::.::.:.: ::. ::. ::.:::.:: :::.::: :.: :.. :..:.:::..::.
CCDS41 EYKLAQALHEMREQHDAQVRLYKEELEQTYHAKLENARLSSEMNTSTVNSAREELMESRM
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB4 RIDSLSAQLSQLQKQLAAKEAKLRDLEDSLARERDTSRRLLAEKEREMAEMRARMQQQLD
::.:::.:::.:::. : ....::: ::.:.:.:::.:..:::::::.: .:::::.
CCDS41 RIESLSSQLSNLQKESRACLERIQELEDLLAKEKDNSRRMLTDKEREMAEIRDQMQQQLN
300 310 320 330 340 350
360 370 380 390 400 410
pF1KB4 EYQELLDIKLALDMEIHAYRKLLEGEEERLRLSPSPTSQRSRGRASSHSSQTQGGGSVTK
.:..:::.:::::::: :::::::::::::.:::::.:. . .:::: : :. :
CCDS41 DYEQLLDVKLALDMEISAYRKLLEGEEERLKLSPSPSSRVTVSRASSSRSVRTTRGK-RK
360 370 380 390 400 410
420 430 440 450 460 470
pF1KB4 KRKLESTESRSS--FSQHARTSGRVAVEEVDEEGKFVRLRNKSNEDQSMGNWQIKRQNGD
. .: .:. :: .:. : ..: : .::.: .:::.::.: :..:: ::.:.. :. ::
CCDS41 RVDVEESEASSSVSISHSASATGNVCIEEIDVDGKFIRLKNTSEQDQPMGGWEMIRKIGD
420 430 440 450 460 470
480 490 500 510 520 530
pF1KB4 DPLLTYRFPPKFTLKAGQVVTIWAAGAGATHSPPTDLVWKAQNTWGCGNSLRTALINSTG
. .:.. ...:::::.::::::.::.: ::::::.:: ::.:: :..... : :: :
CCDS41 TSV-SYKYTSRYVLKAGQTVTIWAANAGVTASPPTDLIWKNQNSWGTGEDVKVILKNSQG
480 490 500 510 520 530
540 550 560 570 580
pF1KB4 EEVAMRKLVRSVTVVEDDEDED---G---DDLLHHHHGSHCSSSGDPAEYNLRSRTVLCG
::::.:. : ..:. :..:.:. : .. : :..:. .:.
CCDS41 EEVAQRSTVFKTTIPEEEEEEEEAAGVVVEEELFHQQGTPRASNRSCAIM
540 550 560 570 580
590 600 610 620 630 640
pF1KB4 TCGQPADKASASGSGAQVGGPISSGSSASSVTVTRSYRSVGGSGGGSFGDNLVTRSYLLG
>>CCDS12090.2 LMNB2 gene_id:84823|Hs108|chr19 (620 aa)
initn: 2005 init1: 1495 opt: 1513 Z-score: 786.0 bits: 155.7 E(32554): 1.9e-37
Smith-Waterman score: 1996; 53.4% identity (80.5% similar) in 599 aa overlap (1-573:21-614)
10 20 30 40
pF1KB4 METPSQRRATRSGAQASSTPLSPTRITRLQEKEDLQELND
: :: :: :. : :::::::..::::::.:.::::
CCDS12 MSPPSPGRRREQRRPRAAATMATPLPGRA---GGPA--TPLSPTRLSRLQEKEELRELND
10 20 30 40 50
50 60 70 80 90 100
pF1KB4 RLAVYIDRVRSLETENAGLRLRITESEEVVSREVSGIKAAYEAELGDARKTLDSVAKERA
::: ::::::.:: :: : :.:.:.:::..:::::::: ::.::.:::..:: .:.:::
CCDS12 RLAHYIDRVRALELENDRLLLKISEKEEVTTREVSGIKALYESELADARRVLDETARERA
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB4 RLQLELSKVREEFKELKARNTKKEGDLIAAQARLKDLEALLNSKEAALSTALSEKRTLEG
:::.:..:.: :. :.. :.::.: .::.:.::::.:.. .:. :..:::.:: ::.
CCDS12 RLQIEIGKLRAELDEVNKSAKKREGELTVAQGRVKDLESLFHRSEVELAAALSDKRGLES
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB4 ELHDLRGQVAKLEAALGEAKKQLQDEMLRRVDAENRLQTMKEELDFQKNIYSEELRETKR
.. .::.:.:: : . . :::::. : : ::: ::: :...:::::.:... ::.:::.:
CCDS12 DVAELRAQLAKAEDGHAVAKKQLEKETLMRVDLENRCQSLQEELDFRKSVFEEEVRETRR
180 190 200 210 220 230
230 240 250 260 270 280
pF1KB4 RHETRLVEIDNGKQREFESRLADALQELRAQHEDQVEQYKKELEKTYSAKLDNARQSAER
::: ::::.:...:.:.. ..:.::.:::.::..::. :: :::.::.::::.:. :...
CCDS12 RHERRLVEVDSSRQQEYDFKMAQALEELRSQHDEQVRLYKLELEQTYQAKLDSAKLSSDQ
240 250 260 270 280 290
290 300 310 320 330 340
pF1KB4 NSNLVGAAHEELQQSRIRIDSLSAQLSQLQKQLAAKEAKLRDLEDSLARERDTSRRLLAE
:.. ..::.:::...:.:..::: ::: :::: .: : ..:.::...: ::: :..:
CCDS12 NDKAASAAREELKEARMRLESLSYQLSGLQKQASAAEDRIRELEEAMAGERDKFRKMLDA
300 310 320 330 340 350
350 360 370 380 390 400
pF1KB4 KEREMAEMRARMQQQLDEYQELLDIKLALDMEIHAYRKLLEGEEERLRLSPSPTSQRSRG
::.::.::: ::::: :::::::.::::::::.:::::::::::::.:::::.:. . .
CCDS12 KEQEMTEMRDVMQQQLAEYQELLDVKLALDMEINAYRKLLEGEEERLKLSPSPSSRVTVS
360 370 380 390 400 410
410 420 430 440
pF1KB4 RASSHSSQT---QGGGSVTKKRKLESTESRSS----------------FSQHARTSGRVA
::.: :: . : . .:...:: : .: ..:.: .:: :.
CCDS12 RATSSSSGSLSATGRLGRSKRKRLEVEEPLGSGPSVLGTGTGGSGGFHLAQQASASGSVS
420 430 440 450 460 470
450 460 470 480 490 500
pF1KB4 VEEVDEEGKFVRLRNKSNEDQSMGNWQIKRQNGDDPLLTYRFPPKFTLKAGQVVTIWAAG
.::.: :::::.:.:.:..:::.:::.:::: . ..:.: ::. :.:::.::.::::
CCDS12 IEEIDLEGKFVQLKNNSDKDQSLGNWRIKRQVLEGEEIAYKFTPKYILRAGQMVTVWAAG
480 490 500 510 520 530
510 520 530 540 550
pF1KB4 AGATHSPPTDLVWKAQNTWGCGNSLRTALINSTGEEVAMRKLVRSVTVVEDDEDED----
::..::::. ::::.:..:: :.:.::.:.:. ::::::: . .: .. :... :.
CCDS12 AGVAHSPPSTLVWKGQSSWGTGESFRTVLVNADGEEVAMRTVKKSSVMRENENGEEEEEE
540 550 560 570 580 590
560 570 580 590 600 610
pF1KB4 ---GDDLLHHHHGSHCSSSGDPAEYNLRSRTVLCGTCGQPADKASASGSGAQVGGPISSG
:.. : :..:. ..:
CCDS12 AEFGEEDLFHQQGDPRTTSRGCYVM
600 610 620
664 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 14:14:47 2016 done: Thu Nov 3 14:14:47 2016
Total Scan time: 3.150 Total Display time: 0.090
Function used was FASTA [36.3.4 Apr, 2011]