FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4051, 341 aa 1>>>pF1KB4051 341 - 341 aa - 341 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 13.3595+/-0.0015; mu= -25.2457+/- 0.083 mean_var=582.2034+/-140.177, 0's: 0 Z-trim(105.1): 71 B-trim: 513 in 1/51 Lambda= 0.053154 statistics sampled from 8202 (8220) to 8202 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.619), E-opt: 0.2 (0.253), width: 16 Scan time: 2.380 The best scores are: opt bits E(32554) CCDS274.1 PDIK1L gene_id:149420|Hs108|chr1 ( 341) 2242 187.5 1.3e-47 CCDS13024.2 STK35 gene_id:140901|Hs108|chr20 ( 534) 1532 133.3 4.5e-31 >>CCDS274.1 PDIK1L gene_id:149420|Hs108|chr1 (341 aa) initn: 2242 init1: 2242 opt: 2242 Z-score: 968.1 bits: 187.5 E(32554): 1.3e-47 Smith-Waterman score: 2242; 100.0% identity (100.0% similar) in 341 aa overlap (1-341:1-341) 10 20 30 40 50 60 pF1KB4 MVSSQPKYDLIREVGRGSYGVVYEAVIRKTSARVAVKKIRCHAPENVELALREFWALSSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS27 MVSSQPKYDLIREVGRGSYGVVYEAVIRKTSARVAVKKIRCHAPENVELALREFWALSSI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 KSQHPNVIHLEECILQKDGMVQKMSHGSNSSLYLQLVETSLKGEIAFDPRSAYYLWFVMD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS27 KSQHPNVIHLEECILQKDGMVQKMSHGSNSSLYLQLVETSLKGEIAFDPRSAYYLWFVMD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 FCDGGDMNEYLLSRKPNRKTNTSFMLQLSSALAFLHKNQIIHRDLKPDNILISQTRLDTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS27 FCDGGDMNEYLLSRKPNRKTNTSFMLQLSSALAFLHKNQIIHRDLKPDNILISQTRLDTS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 DLEPTLKVADFGLSKVCSASGQNPEEPVSVNKCFLSTACGTDFYMAPEVWEGHYTAKADI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS27 DLEPTLKVADFGLSKVCSASGQNPEEPVSVNKCFLSTACGTDFYMAPEVWEGHYTAKADI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 FALGIIIWAMLERITFIDTETKKELLGSYVKQGTEIVPVGEALLENPKMELLIPVKKKSM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS27 FALGIIIWAMLERITFIDTETKKELLGSYVKQGTEIVPVGEALLENPKMELLIPVKKKSM 250 260 270 280 290 300 310 320 330 340 pF1KB4 NGRMKQLIKEMLAANPQDRPDAFELELRLVQIAFKDSSWET ::::::::::::::::::::::::::::::::::::::::: CCDS27 NGRMKQLIKEMLAANPQDRPDAFELELRLVQIAFKDSSWET 310 320 330 340 >>CCDS13024.2 STK35 gene_id:140901|Hs108|chr20 (534 aa) initn: 1491 init1: 527 opt: 1532 Z-score: 671.3 bits: 133.3 E(32554): 4.5e-31 Smith-Waterman score: 1532; 69.3% identity (87.0% similar) in 339 aa overlap (3-332:197-530) 10 20 30 pF1KB4 MVSSQPKYDLIREVGRGSYGVVYEAVIRKTSA :..:.:.:. :.:::::::::::: ...: CCDS13 AAAARAMDPVAAEAPGEAFLARRRPEGGGGSARPRYSLLAEIGRGSYGVVYEAVAGRSGA 170 180 190 200 210 220 40 50 60 70 80 90 pF1KB4 RVAVKKIRCHAPENVELALREFWALSSIKSQHPNVIHLEECILQKDGMVQKMSHGSNSS- ::::::::: ::::::::: :::::.:.: .: ::...:::.::..:..:.::::..:: CCDS13 RVAVKKIRCDAPENVELALAEFWALTSLKRRHQNVVQFEECVLQRNGLAQRMSHGNKSSQ 230 240 250 260 270 280 100 110 120 130 140 150 pF1KB4 LYLQLVETSLKGE-IAFDPRSAYYLWFVMDFCDGGDMNEYLLSRKPNRKTNTSFMLQLSS :::.::::::::: : . ::::::.::.:::.:.:.:::.:. :: ::::::.: CCDS13 LYLRLVETSLKGERILGYAEEPCYLWFVMEFCEGGDLNQYVLSRRPDPATNKSFMLQLTS 290 300 310 320 330 340 160 170 180 190 200 pF1KB4 ALAFLHKNQIIHRDLKPDNILISQTRLDTSDLEPTLKVADFGLSKVCSA------SGQNP :.::::::.:.:::::::::::.. : : : ::::::::::::.. :.. CCDS13 AIAFLHKNHIVHRDLKPDNILITE-RSGT----PILKVADFGLSKVCAGLAPRGKEGNQD 350 360 370 380 390 400 210 220 230 240 250 260 pF1KB4 EEPVSVNKCFLSTACGTDFYMAPEVWEGHYTAKADIFALGIIIWAMLERITFIDTETKKE .. :.::: .::.:::.:::::::::::::::::::::::::::::.:::::::.::::: CCDS13 NKNVNVNKYWLSSACGSDFYMAPEVWEGHYTAKADIFALGIIIWAMIERITFIDSETKKE 410 420 430 440 450 460 270 280 290 300 310 320 pF1KB4 LLGSYVKQGTEIVPVGEALLENPKMELLIPVKKK-SMNGRMKQLIKEMLAANPQDRPDAF :::.:.::::::::::::::::::::: :: :.. ::. .:::.:.::::::::::::: CCDS13 LLGTYIKQGTEIVPVGEALLENPKMELHIPQKRRTSMSEGIKQLLKDMLAANPQDRPDAF 470 480 490 500 510 520 330 340 pF1KB4 ELELRLVQIAFKDSSWET ::: :. :. CCDS13 ELETRMDQVTCAA 530 341 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 21:22:54 2016 done: Thu Nov 3 21:22:55 2016 Total Scan time: 2.380 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]