FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4055, 333 aa 1>>>pF1KB4055 333 - 333 aa - 333 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.6422+/-0.000833; mu= 15.0068+/- 0.050 mean_var=80.1644+/-15.984, 0's: 0 Z-trim(108.5): 29 B-trim: 0 in 0/49 Lambda= 0.143246 statistics sampled from 10228 (10245) to 10228 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.689), E-opt: 0.2 (0.315), width: 16 Scan time: 1.790 The best scores are: opt bits E(32554) CCDS9507.1 EFNB2 gene_id:1948|Hs108|chr13 ( 333) 2243 472.9 1.6e-133 CCDS11120.1 EFNB3 gene_id:1949|Hs108|chr17 ( 340) 839 182.8 3.5e-46 CCDS14391.1 EFNB1 gene_id:1947|Hs108|chrX ( 346) 603 134.0 1.7e-31 >>CCDS9507.1 EFNB2 gene_id:1948|Hs108|chr13 (333 aa) initn: 2243 init1: 2243 opt: 2243 Z-score: 2510.8 bits: 472.9 E(32554): 1.6e-133 Smith-Waterman score: 2243; 100.0% identity (100.0% similar) in 333 aa overlap (1-333:1-333) 10 20 30 40 50 60 pF1KB4 MAVRRDSVWKYCWGVLMVLCRTAISKSIVLEPIYWNSSNSKFLPGQGLVLYPQIGDKLDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS95 MAVRRDSVWKYCWGVLMVLCRTAISKSIVLEPIYWNSSNSKFLPGQGLVLYPQIGDKLDI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 ICPKVDSKTVGQYEYYKVYMVDKDQADRCTIKKENTPLLNCAKPDQDIKFTIKFQEFSPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS95 ICPKVDSKTVGQYEYYKVYMVDKDQADRCTIKKENTPLLNCAKPDQDIKFTIKFQEFSPN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 LWGLEFQKNKDYYIISTSNGSLEGLDNQEGGVCQTRAMKILMKVGQDASSAGSTRNKDPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS95 LWGLEFQKNKDYYIISTSNGSLEGLDNQEGGVCQTRAMKILMKVGQDASSAGSTRNKDPT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 RRPELEAGTNGRSSTTSPFVKPNPGSSTDGNSAGHSGNNILGSEVALFAGIASGCIIFIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS95 RRPELEAGTNGRSSTTSPFVKPNPGSSTDGNSAGHSGNNILGSEVALFAGIASGCIIFIV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 IIITLVVLLLKYRRRHRKHSPQHTTTLSLSTLATPKRSGNNNGSEPSDIIIPLRTADSVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS95 IIITLVVLLLKYRRRHRKHSPQHTTTLSLSTLATPKRSGNNNGSEPSDIIIPLRTADSVF 250 260 270 280 290 300 310 320 330 pF1KB4 CPHYEKVSGDYGHPVYIVQEMPPQSPANIYYKV ::::::::::::::::::::::::::::::::: CCDS95 CPHYEKVSGDYGHPVYIVQEMPPQSPANIYYKV 310 320 330 >>CCDS11120.1 EFNB3 gene_id:1949|Hs108|chr17 (340 aa) initn: 811 init1: 393 opt: 839 Z-score: 942.6 bits: 182.8 E(32554): 3.5e-46 Smith-Waterman score: 839; 42.6% identity (67.1% similar) in 331 aa overlap (14-333:14-340) 10 20 30 40 50 60 pF1KB4 MAVRRDSVWKYCWGVLMVLCRTAISKSIVLEPIYWNSSNSKFLPGQGLVLYPQIGDKLDI :.:..: .. ... :::.::::.:..: : ::::::::.::. CCDS11 MGPPHSGPGGVRVGALLLLGVLGLVSGLSLEPVYWNSANKRFQAEGGYVLYPQIGDRLDL 10 20 30 40 50 60 70 80 90 100 110 pF1KB4 ICPKV---DSKTVGQYEYYKVYMVDKDQADRCTIKKENTPLLNCAKPDQDIKFTIKFQEF .::.. .. .::.::.:.: :. :: . ::.: .:: :..:::::::. CCDS11 LCPRARPPGPHSSPNYEFYKLYLVGGAQGRRCEAPPAPNLLLTCDRPDLDLRFTIKFQEY 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB4 SPNLWGLEFQKNKDYYIISTSNGSLEGLDNQEGGVCQTRAMKILMKVGQDASSAGSTRNK :::::: ::....:::::.::.:. :::.. .:::: ::.::.:..::: : :.. . CCDS11 SPNLWGHEFRSHHDYYIIATSDGTREGLESLQGGVCLTRGMKVLLRVGQ--SPRGGAVPR 130 140 150 160 170 180 190 200 210 220 230 pF1KB4 DPTRRPELEAGTNGRSSTTSPFVKPNPGSST-DGNSAGHSGNNILGSEVALFAGIASGCI :. . .: : . . : . ::. : ...: : : : :. :: :.: CCDS11 KPVSEMPMERDR-GAAHSLEPGKENLPGDPTSNATSRGAEGPLPPPSMPAV-AGAAGGLA 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB4 IFIVIIITLVVLLLKYRRRHRKHSPQHTTTLSLSTLATPKRSGNNN-G---SEPSDIIIP .... . . ::: . .: :.. .. .:... : .::... : CCDS11 LLLLGVAGAGGAMCWRRRRAKPSESRHPGPGSFGRGGSLGLGGGGGMGPREAEPGELGIA 240 250 260 270 280 290 300 310 320 330 pF1KB4 LR---TADSVFCPHYEKVSGDYGHPVYIVQEMPPQSPANIYYKV :: .:: ::::::::::::::::::::. ::::: :::::: CCDS11 LRGGGAADPPFCPHYEKVSGDYGHPVYIVQDGPPQSPPNIYYKV 300 310 320 330 340 >>CCDS14391.1 EFNB1 gene_id:1947|Hs108|chrX (346 aa) initn: 1189 init1: 562 opt: 603 Z-score: 678.9 bits: 134.0 E(32554): 1.7e-31 Smith-Waterman score: 1219; 55.7% identity (77.3% similar) in 343 aa overlap (9-333:8-346) 10 20 30 40 50 pF1KB4 MAVRRDSVWKYCWGVLMV---LCRTAISKSIVLEPIYWNSSNSKFLPGQGLVLYPQIGDK : : : :: ::: : . :::. :.: : ::: :.:::.::.:::: CCDS14 MARPGQRWLGKWLVAMVVWALCRLATPLAKNLEPVSWSSLNPKFLSGKGLVIYPKIGDK 10 20 30 40 50 60 70 80 90 100 110 pF1KB4 LDIICPKVDSKTVGQYEYYKVYMVDKDQADRCTIKKENTPLLNCAKPDQDIKFTIKFQEF ::::::.... :::::.:.: .:: :. . . :..: .:.:.:.:::::::: CCDS14 LDIICPRAEAGR--PYEYYKLYLVRPEQAAACSTVLDPNVLVTCNRPEQEIRFTIKFQEF 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB4 SPNLWGLEFQKNKDYYIISTSNGSLEGLDNQEGGVCQTRAMKILMKVGQDASSAGSTRNK ::: ::::.:..:::: ::::::::::.:.:::::.::.:::.:::::: ... : .. CCDS14 SPNYMGLEFKKHHDYYITSTSNGSLEGLENREGGVCRTRTMKIIMKVGQDPNAV--TPEQ 120 130 140 150 160 170 180 190 200 210 220 pF1KB4 DPTRRPELEAGTNGRSSTTSPFVKPNPGSSTD-------------GNSAGHSGN--NILG : :: :: .. . .: .: . . :.: : :.: ::. .... CCDS14 LTTSRPSKEADNTVKMATQAPGSRGSLGDSDGKHETVNQEEKSGPGASGGSSGDPDGFFN 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB4 SEVALFAGIASGCIIFIVIIITLVVLLLKYRRRHRKHSPQHTTTLSLSTLATPKRSGNNN :.:::::....::.::..::: :.::::: :.:::::. :....:::::::.:: .... CCDS14 SKVALFAAVGAGCVIFLLIIIFLTVLLLKLRKRHRKHTQQRAAALSLSTLASPKGGSGTA 240 250 260 270 280 290 290 300 310 320 330 pF1KB4 GSEPSDIIIPLRTADSVFCPHYEKVSGDYGHPVYIVQEMPPQSPANIYYKV :.:::::::::::... .::::::::::::::::::::::::::::::::: CCDS14 GTEPSDIIIPLRTTENNYCPHYEKVSGDYGHPVYIVQEMPPQSPANIYYKV 300 310 320 330 340 333 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 05:35:04 2016 done: Sat Nov 5 05:35:05 2016 Total Scan time: 1.790 Total Display time: -0.030 Function used was FASTA [36.3.4 Apr, 2011]