FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4057, 687 aa 1>>>pF1KB4057 687 - 687 aa - 687 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.0561+/-0.000433; mu= 21.1465+/- 0.027 mean_var=67.5827+/-13.878, 0's: 0 Z-trim(110.5): 29 B-trim: 0 in 0/50 Lambda= 0.156011 statistics sampled from 18896 (18925) to 18896 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.587), E-opt: 0.2 (0.222), width: 16 Scan time: 10.950 The best scores are: opt bits E(85289) NP_004604 (OMIM: 190196) protein-glutamine gamma-g ( 687) 4668 1060.3 0 NP_001310245 (OMIM: 190196) protein-glutamine gamm ( 687) 4668 1060.3 0 XP_011527330 (OMIM: 190196) PREDICTED: protein-glu ( 687) 4668 1060.3 0 NP_001310247 (OMIM: 190196) protein-glutamine gamm ( 627) 4245 965.1 0 NP_945189 (OMIM: 190196) protein-glutamine gamma-g ( 548) 3720 846.9 0 NP_001310246 (OMIM: 190196) protein-glutamine gamm ( 606) 3693 840.8 0 NP_963925 (OMIM: 603805,609796) protein-glutamine ( 720) 1635 377.7 8.6e-104 NP_443187 (OMIM: 606776) protein-glutamine gamma-g ( 710) 1589 367.3 1.1e-100 XP_016877392 (OMIM: 606776) PREDICTED: protein-glu ( 711) 1589 367.3 1.1e-100 NP_000350 (OMIM: 190195,242300) protein-glutamine ( 817) 1514 350.5 1.5e-95 NP_001241663 (OMIM: 613900,613908) protein-glutami ( 625) 1498 346.8 1.5e-94 NP_945345 (OMIM: 613900,613908) protein-glutamine ( 706) 1498 346.8 1.6e-94 NP_000120 (OMIM: 134570,188050,608446,613225) coag ( 732) 1449 335.8 3.5e-91 NP_003236 (OMIM: 600238) protein-glutamine gamma-g ( 693) 1401 325.0 6e-88 NP_004236 (OMIM: 603805,609796) protein-glutamine ( 638) 1310 304.5 8.2e-82 NP_003232 (OMIM: 600585) protein-glutamine gamma-g ( 684) 1155 269.6 2.7e-71 XP_011532344 (OMIM: 600585) PREDICTED: protein-glu ( 729) 1155 269.6 2.9e-71 NP_001107606 (OMIM: 177070,612690) erythrocyte mem ( 691) 937 220.6 1.6e-56 XP_011519651 (OMIM: 177070,612690) PREDICTED: eryt ( 721) 930 219.0 5e-56 NP_000110 (OMIM: 177070,612690) erythrocyte membra ( 721) 930 219.0 5e-56 XP_011519653 (OMIM: 177070,612690) PREDICTED: eryt ( 721) 930 219.0 5e-56 XP_011519652 (OMIM: 177070,612690) PREDICTED: eryt ( 721) 930 219.0 5e-56 XP_011519654 (OMIM: 177070,612690) PREDICTED: eryt ( 709) 793 188.2 9.5e-47 XP_011519656 (OMIM: 177070,612690) PREDICTED: eryt ( 536) 744 177.0 1.6e-43 XP_005254282 (OMIM: 177070,612690) PREDICTED: eryt ( 656) 600 144.7 1.1e-33 XP_011519655 (OMIM: 177070,612690) PREDICTED: eryt ( 686) 600 144.7 1.1e-33 XP_011520532 (OMIM: 603805,609796) PREDICTED: prot ( 377) 441 108.7 4.1e-23 XP_016878218 (OMIM: 603805,609796) PREDICTED: prot ( 377) 441 108.7 4.1e-23 >>NP_004604 (OMIM: 190196) protein-glutamine gamma-gluta (687 aa) initn: 4668 init1: 4668 opt: 4668 Z-score: 5674.1 bits: 1060.3 E(85289): 0 Smith-Waterman score: 4668; 100.0% identity (100.0% similar) in 687 aa overlap (1-687:1-687) 10 20 30 40 50 60 pF1KB4 MAEELVLERCDLELETNGRDHHTADLCREKLVVRRGQPFWLTLHFEGRNYEASVDSLTFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 MAEELVLERCDLELETNGRDHHTADLCREKLVVRRGQPFWLTLHFEGRNYEASVDSLTFS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 VVTGPAPSQEAGTKARFPLRDAVEEGDWTATVVDQQDCTLSLQLTTPANAPIGLYRLSLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 VVTGPAPSQEAGTKARFPLRDAVEEGDWTATVVDQQDCTLSLQLTTPANAPIGLYRLSLE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 ASTGYQGSSFVLGHFILLFNAWCPADAVYLDSEEERQEYVLTQQGFIYQGSAKFIKNIPW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 ASTGYQGSSFVLGHFILLFNAWCPADAVYLDSEEERQEYVLTQQGFIYQGSAKFIKNIPW 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 NFGQFEDGILDICLILLDVNPKFLKNAGRDCSRRSSPVYVGRVVSGMVNCNDDQGVLLGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 NFGQFEDGILDICLILLDVNPKFLKNAGRDCSRRSSPVYVGRVVSGMVNCNDDQGVLLGR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 WDNNYGDGVSPMSWIGSVDILRRWKNHGCQRVKYGQCWVFAAVACTVLRCLGIPTRVVTN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 WDNNYGDGVSPMSWIGSVDILRRWKNHGCQRVKYGQCWVFAAVACTVLRCLGIPTRVVTN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 YNSAHDQNSNLLIEYFRNEFGEIQGDKSEMIWNFHCWVESWMTRPDLQPGYEGWQALDPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 YNSAHDQNSNLLIEYFRNEFGEIQGDKSEMIWNFHCWVESWMTRPDLQPGYEGWQALDPT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 PQEKSEGTYCCGPVPVRAIKEGDLSTKYDAPFVFAEVNADVVDWIQQDDGSVHKSINRSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 PQEKSEGTYCCGPVPVRAIKEGDLSTKYDAPFVFAEVNADVVDWIQQDDGSVHKSINRSL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB4 IVGLKISTKSVGRDEREDITHTYKYPEGSSEEREAFTRANHLNKLAEKEETGMAMRIRVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 IVGLKISTKSVGRDEREDITHTYKYPEGSSEEREAFTRANHLNKLAEKEETGMAMRIRVG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB4 QSMNMGSDFDVFAHITNNTAEEYVCRLLLCARTVSYNGILGPECGTKYLLNLNLEPFSEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 QSMNMGSDFDVFAHITNNTAEEYVCRLLLCARTVSYNGILGPECGTKYLLNLNLEPFSEK 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB4 SVPLCILYEKYRDCLTESNLIKVRALLVEPVINSYLLAERDLYLENPEIKIRILGEPKQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 SVPLCILYEKYRDCLTESNLIKVRALLVEPVINSYLLAERDLYLENPEIKIRILGEPKQK 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB4 RKLVAEVSLQNPLPVALEGCTFTVEGAGLTEEQKTVEIPDPVEAGEEVKVRMDLLPLHMG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 RKLVAEVSLQNPLPVALEGCTFTVEGAGLTEEQKTVEIPDPVEAGEEVKVRMDLLPLHMG 610 620 630 640 650 660 670 680 pF1KB4 LHKLVVNFESDKLKAVKGFRNVIIGPA ::::::::::::::::::::::::::: NP_004 LHKLVVNFESDKLKAVKGFRNVIIGPA 670 680 >>NP_001310245 (OMIM: 190196) protein-glutamine gamma-gl (687 aa) initn: 4668 init1: 4668 opt: 4668 Z-score: 5674.1 bits: 1060.3 E(85289): 0 Smith-Waterman score: 4668; 100.0% identity (100.0% similar) in 687 aa overlap (1-687:1-687) 10 20 30 40 50 60 pF1KB4 MAEELVLERCDLELETNGRDHHTADLCREKLVVRRGQPFWLTLHFEGRNYEASVDSLTFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAEELVLERCDLELETNGRDHHTADLCREKLVVRRGQPFWLTLHFEGRNYEASVDSLTFS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 VVTGPAPSQEAGTKARFPLRDAVEEGDWTATVVDQQDCTLSLQLTTPANAPIGLYRLSLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VVTGPAPSQEAGTKARFPLRDAVEEGDWTATVVDQQDCTLSLQLTTPANAPIGLYRLSLE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 ASTGYQGSSFVLGHFILLFNAWCPADAVYLDSEEERQEYVLTQQGFIYQGSAKFIKNIPW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ASTGYQGSSFVLGHFILLFNAWCPADAVYLDSEEERQEYVLTQQGFIYQGSAKFIKNIPW 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 NFGQFEDGILDICLILLDVNPKFLKNAGRDCSRRSSPVYVGRVVSGMVNCNDDQGVLLGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NFGQFEDGILDICLILLDVNPKFLKNAGRDCSRRSSPVYVGRVVSGMVNCNDDQGVLLGR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 WDNNYGDGVSPMSWIGSVDILRRWKNHGCQRVKYGQCWVFAAVACTVLRCLGIPTRVVTN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WDNNYGDGVSPMSWIGSVDILRRWKNHGCQRVKYGQCWVFAAVACTVLRCLGIPTRVVTN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 YNSAHDQNSNLLIEYFRNEFGEIQGDKSEMIWNFHCWVESWMTRPDLQPGYEGWQALDPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YNSAHDQNSNLLIEYFRNEFGEIQGDKSEMIWNFHCWVESWMTRPDLQPGYEGWQALDPT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 PQEKSEGTYCCGPVPVRAIKEGDLSTKYDAPFVFAEVNADVVDWIQQDDGSVHKSINRSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PQEKSEGTYCCGPVPVRAIKEGDLSTKYDAPFVFAEVNADVVDWIQQDDGSVHKSINRSL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB4 IVGLKISTKSVGRDEREDITHTYKYPEGSSEEREAFTRANHLNKLAEKEETGMAMRIRVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IVGLKISTKSVGRDEREDITHTYKYPEGSSEEREAFTRANHLNKLAEKEETGMAMRIRVG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB4 QSMNMGSDFDVFAHITNNTAEEYVCRLLLCARTVSYNGILGPECGTKYLLNLNLEPFSEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QSMNMGSDFDVFAHITNNTAEEYVCRLLLCARTVSYNGILGPECGTKYLLNLNLEPFSEK 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB4 SVPLCILYEKYRDCLTESNLIKVRALLVEPVINSYLLAERDLYLENPEIKIRILGEPKQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SVPLCILYEKYRDCLTESNLIKVRALLVEPVINSYLLAERDLYLENPEIKIRILGEPKQK 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB4 RKLVAEVSLQNPLPVALEGCTFTVEGAGLTEEQKTVEIPDPVEAGEEVKVRMDLLPLHMG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RKLVAEVSLQNPLPVALEGCTFTVEGAGLTEEQKTVEIPDPVEAGEEVKVRMDLLPLHMG 610 620 630 640 650 660 670 680 pF1KB4 LHKLVVNFESDKLKAVKGFRNVIIGPA ::::::::::::::::::::::::::: NP_001 LHKLVVNFESDKLKAVKGFRNVIIGPA 670 680 >>XP_011527330 (OMIM: 190196) PREDICTED: protein-glutami (687 aa) initn: 4668 init1: 4668 opt: 4668 Z-score: 5674.1 bits: 1060.3 E(85289): 0 Smith-Waterman score: 4668; 100.0% identity (100.0% similar) in 687 aa overlap (1-687:1-687) 10 20 30 40 50 60 pF1KB4 MAEELVLERCDLELETNGRDHHTADLCREKLVVRRGQPFWLTLHFEGRNYEASVDSLTFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAEELVLERCDLELETNGRDHHTADLCREKLVVRRGQPFWLTLHFEGRNYEASVDSLTFS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 VVTGPAPSQEAGTKARFPLRDAVEEGDWTATVVDQQDCTLSLQLTTPANAPIGLYRLSLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VVTGPAPSQEAGTKARFPLRDAVEEGDWTATVVDQQDCTLSLQLTTPANAPIGLYRLSLE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 ASTGYQGSSFVLGHFILLFNAWCPADAVYLDSEEERQEYVLTQQGFIYQGSAKFIKNIPW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ASTGYQGSSFVLGHFILLFNAWCPADAVYLDSEEERQEYVLTQQGFIYQGSAKFIKNIPW 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 NFGQFEDGILDICLILLDVNPKFLKNAGRDCSRRSSPVYVGRVVSGMVNCNDDQGVLLGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NFGQFEDGILDICLILLDVNPKFLKNAGRDCSRRSSPVYVGRVVSGMVNCNDDQGVLLGR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 WDNNYGDGVSPMSWIGSVDILRRWKNHGCQRVKYGQCWVFAAVACTVLRCLGIPTRVVTN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WDNNYGDGVSPMSWIGSVDILRRWKNHGCQRVKYGQCWVFAAVACTVLRCLGIPTRVVTN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 YNSAHDQNSNLLIEYFRNEFGEIQGDKSEMIWNFHCWVESWMTRPDLQPGYEGWQALDPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YNSAHDQNSNLLIEYFRNEFGEIQGDKSEMIWNFHCWVESWMTRPDLQPGYEGWQALDPT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 PQEKSEGTYCCGPVPVRAIKEGDLSTKYDAPFVFAEVNADVVDWIQQDDGSVHKSINRSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PQEKSEGTYCCGPVPVRAIKEGDLSTKYDAPFVFAEVNADVVDWIQQDDGSVHKSINRSL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB4 IVGLKISTKSVGRDEREDITHTYKYPEGSSEEREAFTRANHLNKLAEKEETGMAMRIRVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IVGLKISTKSVGRDEREDITHTYKYPEGSSEEREAFTRANHLNKLAEKEETGMAMRIRVG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB4 QSMNMGSDFDVFAHITNNTAEEYVCRLLLCARTVSYNGILGPECGTKYLLNLNLEPFSEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QSMNMGSDFDVFAHITNNTAEEYVCRLLLCARTVSYNGILGPECGTKYLLNLNLEPFSEK 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB4 SVPLCILYEKYRDCLTESNLIKVRALLVEPVINSYLLAERDLYLENPEIKIRILGEPKQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SVPLCILYEKYRDCLTESNLIKVRALLVEPVINSYLLAERDLYLENPEIKIRILGEPKQK 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB4 RKLVAEVSLQNPLPVALEGCTFTVEGAGLTEEQKTVEIPDPVEAGEEVKVRMDLLPLHMG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RKLVAEVSLQNPLPVALEGCTFTVEGAGLTEEQKTVEIPDPVEAGEEVKVRMDLLPLHMG 610 620 630 640 650 660 670 680 pF1KB4 LHKLVVNFESDKLKAVKGFRNVIIGPA ::::::::::::::::::::::::::: XP_011 LHKLVVNFESDKLKAVKGFRNVIIGPA 670 680 >>NP_001310247 (OMIM: 190196) protein-glutamine gamma-gl (627 aa) initn: 4245 init1: 4245 opt: 4245 Z-score: 5160.1 bits: 965.1 E(85289): 0 Smith-Waterman score: 4245; 100.0% identity (100.0% similar) in 624 aa overlap (64-687:4-627) 40 50 60 70 80 90 pF1KB4 RRGQPFWLTLHFEGRNYEASVDSLTFSVVTGPAPSQEAGTKARFPLRDAVEEGDWTATVV :::::::::::::::::::::::::::::: NP_001 MAEGPAPSQEAGTKARFPLRDAVEEGDWTATVV 10 20 30 100 110 120 130 140 150 pF1KB4 DQQDCTLSLQLTTPANAPIGLYRLSLEASTGYQGSSFVLGHFILLFNAWCPADAVYLDSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DQQDCTLSLQLTTPANAPIGLYRLSLEASTGYQGSSFVLGHFILLFNAWCPADAVYLDSE 40 50 60 70 80 90 160 170 180 190 200 210 pF1KB4 EERQEYVLTQQGFIYQGSAKFIKNIPWNFGQFEDGILDICLILLDVNPKFLKNAGRDCSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EERQEYVLTQQGFIYQGSAKFIKNIPWNFGQFEDGILDICLILLDVNPKFLKNAGRDCSR 100 110 120 130 140 150 220 230 240 250 260 270 pF1KB4 RSSPVYVGRVVSGMVNCNDDQGVLLGRWDNNYGDGVSPMSWIGSVDILRRWKNHGCQRVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RSSPVYVGRVVSGMVNCNDDQGVLLGRWDNNYGDGVSPMSWIGSVDILRRWKNHGCQRVK 160 170 180 190 200 210 280 290 300 310 320 330 pF1KB4 YGQCWVFAAVACTVLRCLGIPTRVVTNYNSAHDQNSNLLIEYFRNEFGEIQGDKSEMIWN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YGQCWVFAAVACTVLRCLGIPTRVVTNYNSAHDQNSNLLIEYFRNEFGEIQGDKSEMIWN 220 230 240 250 260 270 340 350 360 370 380 390 pF1KB4 FHCWVESWMTRPDLQPGYEGWQALDPTPQEKSEGTYCCGPVPVRAIKEGDLSTKYDAPFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FHCWVESWMTRPDLQPGYEGWQALDPTPQEKSEGTYCCGPVPVRAIKEGDLSTKYDAPFV 280 290 300 310 320 330 400 410 420 430 440 450 pF1KB4 FAEVNADVVDWIQQDDGSVHKSINRSLIVGLKISTKSVGRDEREDITHTYKYPEGSSEER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FAEVNADVVDWIQQDDGSVHKSINRSLIVGLKISTKSVGRDEREDITHTYKYPEGSSEER 340 350 360 370 380 390 460 470 480 490 500 510 pF1KB4 EAFTRANHLNKLAEKEETGMAMRIRVGQSMNMGSDFDVFAHITNNTAEEYVCRLLLCART :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EAFTRANHLNKLAEKEETGMAMRIRVGQSMNMGSDFDVFAHITNNTAEEYVCRLLLCART 400 410 420 430 440 450 520 530 540 550 560 570 pF1KB4 VSYNGILGPECGTKYLLNLNLEPFSEKSVPLCILYEKYRDCLTESNLIKVRALLVEPVIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VSYNGILGPECGTKYLLNLNLEPFSEKSVPLCILYEKYRDCLTESNLIKVRALLVEPVIN 460 470 480 490 500 510 580 590 600 610 620 630 pF1KB4 SYLLAERDLYLENPEIKIRILGEPKQKRKLVAEVSLQNPLPVALEGCTFTVEGAGLTEEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SYLLAERDLYLENPEIKIRILGEPKQKRKLVAEVSLQNPLPVALEGCTFTVEGAGLTEEQ 520 530 540 550 560 570 640 650 660 670 680 pF1KB4 KTVEIPDPVEAGEEVKVRMDLLPLHMGLHKLVVNFESDKLKAVKGFRNVIIGPA :::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KTVEIPDPVEAGEEVKVRMDLLPLHMGLHKLVVNFESDKLKAVKGFRNVIIGPA 580 590 600 610 620 >>NP_945189 (OMIM: 190196) protein-glutamine gamma-gluta (548 aa) initn: 3717 init1: 3717 opt: 3720 Z-score: 4522.3 bits: 846.9 E(85289): 0 Smith-Waterman score: 3720; 99.3% identity (99.4% similar) in 545 aa overlap (1-545:1-543) 10 20 30 40 50 60 pF1KB4 MAEELVLERCDLELETNGRDHHTADLCREKLVVRRGQPFWLTLHFEGRNYEASVDSLTFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_945 MAEELVLERCDLELETNGRDHHTADLCREKLVVRRGQPFWLTLHFEGRNYEASVDSLTFS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 VVTGPAPSQEAGTKARFPLRDAVEEGDWTATVVDQQDCTLSLQLTTPANAPIGLYRLSLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_945 VVTGPAPSQEAGTKARFPLRDAVEEGDWTATVVDQQDCTLSLQLTTPANAPIGLYRLSLE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 ASTGYQGSSFVLGHFILLFNAWCPADAVYLDSEEERQEYVLTQQGFIYQGSAKFIKNIPW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_945 ASTGYQGSSFVLGHFILLFNAWCPADAVYLDSEEERQEYVLTQQGFIYQGSAKFIKNIPW 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 NFGQFEDGILDICLILLDVNPKFLKNAGRDCSRRSSPVYVGRVVSGMVNCNDDQGVLLGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_945 NFGQFEDGILDICLILLDVNPKFLKNAGRDCSRRSSPVYVGRVVSGMVNCNDDQGVLLGR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 WDNNYGDGVSPMSWIGSVDILRRWKNHGCQRVKYGQCWVFAAVACTVLRCLGIPTRVVTN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_945 WDNNYGDGVSPMSWIGSVDILRRWKNHGCQRVKYGQCWVFAAVACTVLRCLGIPTRVVTN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 YNSAHDQNSNLLIEYFRNEFGEIQGDKSEMIWNFHCWVESWMTRPDLQPGYEGWQALDPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_945 YNSAHDQNSNLLIEYFRNEFGEIQGDKSEMIWNFHCWVESWMTRPDLQPGYEGWQALDPT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 PQEKSEGTYCCGPVPVRAIKEGDLSTKYDAPFVFAEVNADVVDWIQQDDGSVHKSINRSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_945 PQEKSEGTYCCGPVPVRAIKEGDLSTKYDAPFVFAEVNADVVDWIQQDDGSVHKSINRSL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB4 IVGLKISTKSVGRDEREDITHTYKYPEGSSEEREAFTRANHLNKLAEKEETGMAMRIRVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_945 IVGLKISTKSVGRDEREDITHTYKYPEGSSEEREAFTRANHLNKLAEKEETGMAMRIRVG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB4 QSMNMGSDFDVFAHITNNTAEEYVCRLLLCARTVSYNGILGPECGTKYLLNLNLEPFSEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: : NP_945 QSMNMGSDFDVFAHITNNTAEEYVCRLLLCARTVSYNGILGPECGTKYLLNLNLEPFSGK 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB4 SVPLCILYEKYRDCLTESNLIKVRALLVEPVINSYLLAERDLYLENPEIKIRILGEPKQK . :: NP_945 A--LCSWSIC >>NP_001310246 (OMIM: 190196) protein-glutamine gamma-gl (606 aa) initn: 3693 init1: 3693 opt: 3693 Z-score: 4488.8 bits: 840.8 E(85289): 0 Smith-Waterman score: 3944; 88.2% identity (88.2% similar) in 687 aa overlap (1-687:1-606) 10 20 30 40 50 60 pF1KB4 MAEELVLERCDLELETNGRDHHTADLCREKLVVRRGQPFWLTLHFEGRNYEASVDSLTFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAEELVLERCDLELETNGRDHHTADLCREKLVVRRGQPFWLTLHFEGRNYEASVDSLTFS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 VVTGPAPSQEAGTKARFPLRDAVEEGDWTATVVDQQDCTLSLQLTTPANAPIGLYRLSLE ::: NP_001 VVT--------------------------------------------------------- 130 140 150 160 170 180 pF1KB4 ASTGYQGSSFVLGHFILLFNAWCPADAVYLDSEEERQEYVLTQQGFIYQGSAKFIKNIPW :::::::::::::::::::::::::::::::::::: NP_001 ------------------------ADAVYLDSEEERQEYVLTQQGFIYQGSAKFIKNIPW 70 80 90 190 200 210 220 230 240 pF1KB4 NFGQFEDGILDICLILLDVNPKFLKNAGRDCSRRSSPVYVGRVVSGMVNCNDDQGVLLGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NFGQFEDGILDICLILLDVNPKFLKNAGRDCSRRSSPVYVGRVVSGMVNCNDDQGVLLGR 100 110 120 130 140 150 250 260 270 280 290 300 pF1KB4 WDNNYGDGVSPMSWIGSVDILRRWKNHGCQRVKYGQCWVFAAVACTVLRCLGIPTRVVTN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WDNNYGDGVSPMSWIGSVDILRRWKNHGCQRVKYGQCWVFAAVACTVLRCLGIPTRVVTN 160 170 180 190 200 210 310 320 330 340 350 360 pF1KB4 YNSAHDQNSNLLIEYFRNEFGEIQGDKSEMIWNFHCWVESWMTRPDLQPGYEGWQALDPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YNSAHDQNSNLLIEYFRNEFGEIQGDKSEMIWNFHCWVESWMTRPDLQPGYEGWQALDPT 220 230 240 250 260 270 370 380 390 400 410 420 pF1KB4 PQEKSEGTYCCGPVPVRAIKEGDLSTKYDAPFVFAEVNADVVDWIQQDDGSVHKSINRSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PQEKSEGTYCCGPVPVRAIKEGDLSTKYDAPFVFAEVNADVVDWIQQDDGSVHKSINRSL 280 290 300 310 320 330 430 440 450 460 470 480 pF1KB4 IVGLKISTKSVGRDEREDITHTYKYPEGSSEEREAFTRANHLNKLAEKEETGMAMRIRVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IVGLKISTKSVGRDEREDITHTYKYPEGSSEEREAFTRANHLNKLAEKEETGMAMRIRVG 340 350 360 370 380 390 490 500 510 520 530 540 pF1KB4 QSMNMGSDFDVFAHITNNTAEEYVCRLLLCARTVSYNGILGPECGTKYLLNLNLEPFSEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QSMNMGSDFDVFAHITNNTAEEYVCRLLLCARTVSYNGILGPECGTKYLLNLNLEPFSEK 400 410 420 430 440 450 550 560 570 580 590 600 pF1KB4 SVPLCILYEKYRDCLTESNLIKVRALLVEPVINSYLLAERDLYLENPEIKIRILGEPKQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SVPLCILYEKYRDCLTESNLIKVRALLVEPVINSYLLAERDLYLENPEIKIRILGEPKQK 460 470 480 490 500 510 610 620 630 640 650 660 pF1KB4 RKLVAEVSLQNPLPVALEGCTFTVEGAGLTEEQKTVEIPDPVEAGEEVKVRMDLLPLHMG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RKLVAEVSLQNPLPVALEGCTFTVEGAGLTEEQKTVEIPDPVEAGEEVKVRMDLLPLHMG 520 530 540 550 560 570 670 680 pF1KB4 LHKLVVNFESDKLKAVKGFRNVIIGPA ::::::::::::::::::::::::::: NP_001 LHKLVVNFESDKLKAVKGFRNVIIGPA 580 590 600 >>NP_963925 (OMIM: 603805,609796) protein-glutamine gamm (720 aa) initn: 1240 init1: 922 opt: 1635 Z-score: 1984.4 bits: 377.7 E(85289): 8.6e-104 Smith-Waterman score: 1833; 41.1% identity (67.1% similar) in 721 aa overlap (1-684:1-716) 10 20 30 40 50 60 pF1KB4 MAEELVLERCDLELETNGRDHHTADLCREKLVVRRGQPFWLTLHFEGRNYEASVDSLTFS ::. : . ::. :. ::: .. ..:.::::: : :::.:..:... ..:.. : NP_963 MAQGLEVALTDLQSSRNNVRHHTEEITVDHLLVRRGQAFNLTLYFRNRSFQPGLDNIIFV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 VVTGPAPSQEAGTKARFPLRDAVEEGDWTATVVDQQDCTLSLQLTTPANAPIGLYRLSLE : ::: :. ::.: : : . : : . . . ..: .: .: .: : :... NP_963 VETGPLPDLALGTRAVFSLARHHSPSPWIAWLETNGATSTEVSLCAPPTAAVGRYLLKIH 70 80 90 100 110 120 130 140 150 160 170 pF1KB4 ASTGYQGS--SFVLGHFILLFNAWCPADAVYLDSEEERQEYVLTQQGFIYQGSAKFIKNI .. .::: .. ::.:::::: ::: :::::::: .:::::... ::::::: ..:. NP_963 IDS-FQGSVTAYQLGEFILLFNPWCPEDAVYLDSEPQRQEYVMNDYGFIYQGSKNWIRPC 130 140 150 160 170 180 190 200 210 220 230 pF1KB4 PWNFGQFEDGILDICLILLDVNPKFLKNAGRDCSRRSSPVYVGRVVSGMVNCNDDQGVLL :::.::::: :.:::: ::: . .: . . ::. :.:::::.::: .:.: :::.::: NP_963 PWNYGQFEDKIIDICLKLLDKSLHFQTDPATDCALRGSPVYVSRVVCAMINSNDDNGVLN 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB4 GRWDNNYGDGVSPMSWIGSVDILRRWKNHGCQRVKYGQCWVFAAVACTVLRCLGIPTRVV : :..:: ::..: : ::: ::..:. ::: :.:::::::::: :::.:::::::::. NP_963 GNWSENYTDGANPAEWTGSVAILKQWNATGCQPVRYGQCWVFAAVMCTVMRCLGIPTRVI 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB4 TNYNSAHDQNSNLLIEYFRNEFGEIQGDKS-EMIWNFHCWVESWMTRPDLQPGYEGWQAL ::..:.:: ..::.:. . .. :.: :.:. . ::::: : : ::.: :: :.: :::.: NP_963 TNFDSGHDTDGNLIIDEYYDNTGRILGNKKKDTIWNFHVWNECWMARKDLPPAYGGWQVL 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB4 DPTPQEKSEGTYCCGPVPVRAIKEGDLSTKYDAPFVFAEVNADVVDWIQQDDGSVHKSIN : :::: :.:.:::::. :::::::... .::.::::. :::: ..:. : :. .: . NP_963 DATPQEMSNGVYCCGPASVRAIKEGEVDLNYDTPFVFSMVNADCMSWLVQG-GKEQKLHQ 360 370 380 390 400 410 420 430 440 450 460 pF1KB4 RSLIVGLKISTKSVGRDEREDITHTYKYPEGSSEEREAFTRAN----------------- . :: :::::. :::.:::..::: ::: .::..: .: NP_963 DTSSVGNFISTKSIQSDERDDITENYKYEEGSLQERQVFLKALQKLKARSFHGSQRGAEL 420 430 440 450 460 470 470 480 490 500 pF1KB4 ----------------HLNKLAEKEETGMAMRIRVGQSMNMGSDFDVFAHITNNTAEEYV : .: .. . ....... . :::.:. : ... NP_963 QPSRPTSLSQDSPRSLHTPSLRPSDVVQVSLKFKLLDPPNMGQDICFVLLALNMSSQFKD 480 490 500 510 520 530 510 520 530 540 550 560 pF1KB4 CRLLLCARTVSYNGI-LGPECGTKYLLNLNLEPFSEKSVPLCILYEKYRDCLTESNLIKV .. : :... ..: :.: ...:. : :. : : : .: . :. ..::.. NP_963 LKVNLSAQSLLHDGSPLSPFWQDTAFITLS--PKEAKTYPCKISYSQYSQYLSTDKLIRI 540 550 560 570 580 590 570 580 590 600 610 620 pF1KB4 RALLVEPVINSYLLAERDLYLENPEIKIRILGEPKQKRKLVAEVSLQNPLPVALEGCTFT :: : .:... . : : : : .:: .. : .: ..::: .: :..: NP_963 SALGEEKSSPEKILVNKIITLSYPSITINVLGAAVVNQPLSIQVIFSNPLSEQVEDCVLT 600 610 620 630 640 650 630 640 650 660 670 680 pF1KB4 VEGAGLTEEQKTVEIPDPVEAGEEVKVRMDLLPLHMGLHKLVVNFESDKLKAVKGFRNVI :::.:: ..:. : . .. ..... .. .:.. : ... .:..:.:.: .::.::: NP_963 VEGSGLFKKQQKVFL-GVLKPQHQASIILETVPFKSGQRQIQANMRSNKFKDIKGYRNVY 660 670 680 690 700 710 pF1KB4 IGPA . NP_963 VDFAL 720 >>NP_443187 (OMIM: 606776) protein-glutamine gamma-gluta (710 aa) initn: 1512 init1: 801 opt: 1589 Z-score: 1928.5 bits: 367.3 E(85289): 1.1e-100 Smith-Waterman score: 1812; 41.9% identity (68.8% similar) in 704 aa overlap (5-684:7-704) 10 20 30 40 50 pF1KB4 MAEELVLERCDLELETNGRDHHTADLCREKLVVRRGQPFWLTLHFEGRNYEASVDSLT : :: ::. :...::: .. ..:.:::::::.: : : .: .... : .: NP_443 MDQVATLRLESVDLQSSRNNKEHHTQEMGVKRLTVRRGQPFYLRLSF-SRPFQSQNDHIT 10 20 30 40 50 60 70 80 90 100 110 pF1KB4 FSVVTGPAPSQEAGTKARFPLRDAVEEGD-WTATVVDQQDCTLSLQLTTPANAPIGLYRL : . ::: ::. ::.: : : :. :. :.:. .. .:...: ::::: :: : : NP_443 FVAETGPKPSELLGTRATFFLTR-VQPGNVWSASDFTIDSNSLQVSLFTPANAVIGHYTL 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB4 SLEASTGYQGSS--FVLGHFILLFNAWCPADAVYLDSEEERQEYVLTQQGFIYQGSAKFI ..: : : :: : . :: :::::: : : : ::: :: :::.. . ::.:.: .:: NP_443 KIEISQG-QGHSVTYPLGTFILLFNPWSPEDDVYLPSEILLQEYIMRDYGFVYKGHERFI 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB4 KNIPWNFGQFEDGILDICLILLDVNPKFLKNAGRDCSRRSSPVYVGRVVSGMVNCNDDQG . :::.::::. :.:::. .:. . ::: ..:::.:.. ::: ::::.:.: :::.: NP_443 TSWPWNYGQFEEDIIDICFEILNKSLYHLKNPAKDCSQRNDVVYVCRVVSAMINSNDDNG 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB4 VLLGRWDNNYGDGVSPMSWIGSVDILRRWKNHGCQRVKYGQCWVFAAVACTVLRCLGIPT :: : : ..:. ::::. : ::: ::..:. .: : ::::::::::.: :::.::::.:: NP_443 VLQGNWGEDYSKGVSPLEWKGSVAILQQWSARGGQPVKYGQCWVFASVMCTVMRCLGVPT 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB4 RVVTNYNSAHDQNSNLLIEYFRNEFGEIQG-DKSEMIWNFHCWVESWMTRPDLQPGYEGW :::.:. :::. . :: :. . .. .:. . .: . ::::: : : :: : :: :::.:: NP_443 RVVSNFRSAHNVDRNLTIDTYYDRNAEMLSTQKRDKIWNFHVWNECWMIRKDLPPGYNGW 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB4 QALDPTPQEKSEGTYCCGPVPVRAIKEGDLSTKYDAPFVFAEVNADVVDWIQQDDGSVHK :.::::::. : : .::::. :.::.:::. ::.:::.:::::: : :. : . . NP_443 QVLDPTPQQTSSGLFCCGPASVKAIREGDVHLAYDTPFVYAEVNADEVIWLLGDGQAQEI 360 370 380 390 400 410 420 430 440 450 460 pF1KB4 SINRSLIVGLKISTKSVGRDEREDITHTYKYPEGSSEEREAFTRANH---------LNKL . . .: .:::: :: :.:..:: .::::::: ::: .: .:.. : : NP_443 LAHNTSSIGKEISTKMVGSDQRQSITSSYKYPEGSPEERAVFMKASRKMLGPQRASLPFL 420 430 440 450 460 470 470 480 490 500 510 pF1KB4 AEKEETGM-----AMRIRVGQSMNMGSDFDVFAHIT---NNTAEEYVCRLLL--CARTVS : :. ....... . :.:.... .: ..: . :.. ::... NP_443 DLLESGGLRDQPAQLQLHLARIPEWGQDLQLLLRIQRVPDSTHPRGPIGLVVRFCAQALL 480 490 500 510 520 530 520 530 540 550 560 570 pF1KB4 YNGILGPECGT-KYLLNLNLEPFSEKSVPLCILYEKYRDCLTESNLIKVRALLVEPVINS ..: : . .. . .::. .: . :: . : .::. ::. .::.: .. . NP_443 HGG--GTQKPFWRHTVRMNLDFGKETQWPLLLPYSNYRNKLTDEKLIRVSGIAEVEETGR 540 550 560 570 580 590 580 590 600 610 620 630 pF1KB4 YLLAERDLYLENPEIKIRILGEPKQKRKLVAEVSLQNPLPVALEGCTFTVEGAGLTEEQK .:. .:. :: :...:.. . . . : ..:.: : : ::: .::...::.:: . : NP_443 SMLVLKDICLEPPHLSIEVSERAEVGKALRVHVTLTNTLMVALSSCTMVLEGSGLINGQI 600 610 620 630 640 650 640 650 660 670 680 pF1KB4 TVEIPDPVEAGEEVKVRMDLLPLHMGLHKLVVNFESDKLKAVKGFRNVIIGPA . .. : ::. .....:: : . : ..: : . :...: .::...... NP_443 AKDLGTLV-AGHTLQIQLDLYPTKAGPRQLQVLISSNEVKEIKGYKDIFVTVAGAP 660 670 680 690 700 710 >>XP_016877392 (OMIM: 606776) PREDICTED: protein-glutami (711 aa) initn: 1512 init1: 801 opt: 1589 Z-score: 1928.5 bits: 367.3 E(85289): 1.1e-100 Smith-Waterman score: 1812; 41.9% identity (68.8% similar) in 704 aa overlap (5-684:8-705) 10 20 30 40 50 pF1KB4 MAEELVLERCDLELETNGRDHHTADLCREKLVVRRGQPFWLTLHFEGRNYEASVDSL : :: ::. :...::: .. ..:.:::::::.: : : .: .... : . XP_016 MIPTMATLRLESVDLQSSRNNKEHHTQEMGVKRLTVRRGQPFYLRLSF-SRPFQSQNDHI 10 20 30 40 50 60 70 80 90 100 110 pF1KB4 TFSVVTGPAPSQEAGTKARFPLRDAVEEGD-WTATVVDQQDCTLSLQLTTPANAPIGLYR :: . ::: ::. ::.: : : :. :. :.:. .. .:...: ::::: :: : XP_016 TFVAETGPKPSELLGTRATFFLTR-VQPGNVWSASDFTIDSNSLQVSLFTPANAVIGHYT 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB4 LSLEASTGYQGSS--FVLGHFILLFNAWCPADAVYLDSEEERQEYVLTQQGFIYQGSAKF :..: : : :: : . :: :::::: : : : ::: :: :::.. . ::.:.: .: XP_016 LKIEISQG-QGHSVTYPLGTFILLFNPWSPEDDVYLPSEILLQEYIMRDYGFVYKGHERF 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB4 IKNIPWNFGQFEDGILDICLILLDVNPKFLKNAGRDCSRRSSPVYVGRVVSGMVNCNDDQ : . :::.::::. :.:::. .:. . ::: ..:::.:.. ::: ::::.:.: :::. XP_016 ITSWPWNYGQFEEDIIDICFEILNKSLYHLKNPAKDCSQRNDVVYVCRVVSAMINSNDDN 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB4 GVLLGRWDNNYGDGVSPMSWIGSVDILRRWKNHGCQRVKYGQCWVFAAVACTVLRCLGIP ::: : : ..:. ::::. : ::: ::..:. .: : ::::::::::.: :::.::::.: XP_016 GVLQGNWGEDYSKGVSPLEWKGSVAILQQWSARGGQPVKYGQCWVFASVMCTVMRCLGVP 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB4 TRVVTNYNSAHDQNSNLLIEYFRNEFGEIQG-DKSEMIWNFHCWVESWMTRPDLQPGYEG ::::.:. :::. . :: :. . .. .:. . .: . ::::: : : :: : :: :::.: XP_016 TRVVSNFRSAHNVDRNLTIDTYYDRNAEMLSTQKRDKIWNFHVWNECWMIRKDLPPGYNG 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB4 WQALDPTPQEKSEGTYCCGPVPVRAIKEGDLSTKYDAPFVFAEVNADVVDWIQQDDGSVH ::.::::::. : : .::::. :.::.:::. ::.:::.:::::: : :. : . . XP_016 WQVLDPTPQQTSSGLFCCGPASVKAIREGDVHLAYDTPFVYAEVNADEVIWLLGDGQAQE 360 370 380 390 400 410 420 430 440 450 460 pF1KB4 KSINRSLIVGLKISTKSVGRDEREDITHTYKYPEGSSEEREAFTRANH---------LNK . . .: .:::: :: :.:..:: .::::::: ::: .: .:.. : XP_016 ILAHNTSSIGKEISTKMVGSDQRQSITSSYKYPEGSPEERAVFMKASRKMLGPQRASLPF 420 430 440 450 460 470 470 480 490 500 510 pF1KB4 LAEKEETGM-----AMRIRVGQSMNMGSDFDVFAHIT---NNTAEEYVCRLLL--CARTV : : :. ....... . :.:.... .: ..: . :.. ::... XP_016 LDLLESGGLRDQPAQLQLHLARIPEWGQDLQLLLRIQRVPDSTHPRGPIGLVVRFCAQAL 480 490 500 510 520 530 520 530 540 550 560 570 pF1KB4 SYNGILGPECGT-KYLLNLNLEPFSEKSVPLCILYEKYRDCLTESNLIKVRALLVEPVIN ..: : . .. . .::. .: . :: . : .::. ::. .::.: .. . XP_016 LHGG--GTQKPFWRHTVRMNLDFGKETQWPLLLPYSNYRNKLTDEKLIRVSGIAEVEETG 540 550 560 570 580 590 580 590 600 610 620 630 pF1KB4 SYLLAERDLYLENPEIKIRILGEPKQKRKLVAEVSLQNPLPVALEGCTFTVEGAGLTEEQ .:. .:. :: :...:.. . . . : ..:.: : : ::: .::...::.:: . : XP_016 RSMLVLKDICLEPPHLSIEVSERAEVGKALRVHVTLTNTLMVALSSCTMVLEGSGLINGQ 600 610 620 630 640 650 640 650 660 670 680 pF1KB4 KTVEIPDPVEAGEEVKVRMDLLPLHMGLHKLVVNFESDKLKAVKGFRNVIIGPA . .. : ::. .....:: : . : ..: : . :...: .::...... XP_016 IAKDLGTLV-AGHTLQIQLDLYPTKAGPRQLQVLISSNEVKEIKGYKDIFVTVAGAP 660 670 680 690 700 710 >>NP_000350 (OMIM: 190195,242300) protein-glutamine gamm (817 aa) initn: 741 init1: 647 opt: 1514 Z-score: 1836.4 bits: 350.5 E(85289): 1.5e-95 Smith-Waterman score: 1514; 37.5% identity (67.0% similar) in 701 aa overlap (5-687:110-789) 10 20 30 pF1KB4 MAEELVLERCDL---ELETNGRDHHTADLCREKL ::.. :: . . : :.::: . ..: NP_000 PGSRGSDSRRPVSRGSGVNAAGDGTIREGMLVVNGVDLLSSRSDQNRREHHTDEYEYDEL 80 90 100 110 120 130 40 50 60 70 80 90 pF1KB4 VVRRGQPFWLTLHFEGRNYEASVDSLTFSVVTGPAPSQEAGTKARFPLRDAVEEGDWTAT .::::::: . : . .:.::.: : .:. .. : : ::.. .:. . : : : NP_000 IVRRGQPFHMLL-LLSRTYESS-DRITLELLIGNNPEVGKGTHVIIPVGKG-GSGGWKAQ 140 150 160 170 180 190 100 110 120 130 140 pF1KB4 VVDQQDCTLSLQLTTPANAPIGLYRLSLEASTGYQGSSFVL-----GHFILLFNAWCPAD :: . .:.:.. : :: :: ......... ... : : ... .::: ::: : NP_000 VVKASGQNLNLRVHTSPNAIIGKFQFTVRTQS--DAGEFQLPFDPRNEIYILFNPWCPED 200 210 220 230 240 250 150 160 170 180 190 200 pF1KB4 AVYLDSEEERQEYVLTQQGFIYQGSAKFIKNIPWNFGQFEDGILDICLILLDVNPKFLKN ::.: :. ::::::...: :: :. : . ::.:::. :.:: :: .:: NP_000 IVYVDHEDWRQEYVLNESGRIYYGTEAQIGERTWNYGQFDHGVLDACLYILD-------R 260 270 280 290 300 210 220 230 240 250 260 pF1KB4 AGRDCSRRSSPVYVGRVVSGMVNCNDDQGVLLGRWDNNYGDGVSPMSWIGSVDILRRWKN : . :..:: :.::.:.::: ::.:::.: :...:. :..: .:.:::.:: . NP_000 RGMPYGGRGDPVNVSRVISAMVNSLDDNGVLIGNWSGDYSRGTNPSAWVGSVEILLSYLR 310 320 330 340 350 360 270 280 290 300 310 320 pF1KB4 HGCQRVKYGQCWVFAAVACTVLRCLGIPTRVVTNYNSAHDQNSNLLIE-YFRNEFGEIQG : : ::::::::.:. :::::::. ::.:::.::::: ...: .. :: ... .. NP_000 TG-YSVPYGQCWVFAGVTTTVLRCLGLATRTVTNFNSAHDTDTSLTMDIYFDENMKPLEH 370 380 390 400 410 420 330 340 350 360 370 380 pF1KB4 DKSEMIWNFHCWVESWMTRPDLQPGYEGWQALDPTPQEKSEGTYCCGPVPVRAIKEGDLS . . .:::: : . :: :::: :..:::..: :::: : : .:::: :..::.: . NP_000 LNHDSVWNFHVWNDCWMKRPDLPSGFDGWQVVDATPQETSSGIFCCGPCSVESIKNGLVY 430 440 450 460 470 480 390 400 410 420 430 440 pF1KB4 TKYDAPFVFAEVNADVVDWIQQDDGSVHKSINRSLIVGLKISTKSVGRDEREDITHTYKY :::.::.:::::.: : : .::::: . . .: : ::... . :::::. ::. NP_000 MKYDTPFIFAEVNSDKVYWQRQDDGSFKIVYVEEKAIGTLIVTKAISSNMREDITYLYKH 490 500 510 520 530 540 450 460 470 480 490 500 pF1KB4 PEGSSEEREAF-TRANHLNKLAEKEETG----MAMRIRVGQSMNMGSDFDVFAHITNNTA ::::. ::.: : : : .: . : .::.... :. ::.:. : . . :... NP_000 PEGSDAERKAVETAAAHGSKPNVYANRGSAEDVAMQVEA-QDAVMGQDLMVSVMLINHSS 550 560 570 580 590 600 510 520 530 540 550 pF1KB4 EEYVCRLLLCARTVSYNGILGPECG-TKYLLNLNLEPFSEKSVPLCILYEKYRDCLTESN . . .: : .. :.:. : :: ...: : . : . . :..:: :.... NP_000 SRRTVKLHLYLSVTFYTGVSGTIFKETKK--EVELAPGASDRVTMPVAYKEYRPHLVDQG 610 620 630 640 650 660 560 570 580 590 600 610 pF1KB4 --LIKVRALLVEPVINSYLLAERDLY-LENPEIKIRILGEPKQKRKLVAEVSLQNPLPVA :..: . . : .. .::.. . :..:.... .:: .. ... ..:::::. NP_000 AMLLNVSGHVKE---SGQVLAKQHTFRLRTPDLSLTLLGAAVVGQECEVQIVFKNPLPVT 670 680 690 700 710 720 620 630 640 650 660 670 pF1KB4 LEGCTFTVEGAGLTEEQKTVEIPDPVEAGEEVKVRMDLLPLHMGLHKLVVNFESDKLKAV : . .: .::.:: .. : ... : . ..: : .:....:.. : ..:.....: .:. : NP_000 LTNVVFRLEGSGL-QRPKILNVGD-IGGNETVTLRQSFVPVRPGPRQLIASLDSPQLSQV 730 740 750 760 770 680 pF1KB4 KGFRNVIIGPA .: .: ..:: NP_000 HGVIQVDVAPAPGDGGFFSDAGGDSHLGETIPMASRGGA 780 790 800 810 687 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 07:11:26 2016 done: Sat Nov 5 07:11:27 2016 Total Scan time: 10.950 Total Display time: 0.200 Function used was FASTA [36.3.4 Apr, 2011]