Result of FASTA (omim) for
pF1KB4058
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB4058, 537 aa
1>>>pF1KB4058 537 - 537 aa - 537 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 16.3990+/-0.000444; mu= -31.9602+/- 0.028
mean_var=777.3550+/-158.777, 0's: 0 Z-trim(126.1): 388 B-trim: 0 in 0/61
Lambda= 0.046001
statistics sampled from 50855 (51274) to 50855 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.842), E-opt: 0.2 (0.601), width: 16
Scan time: 9.930
The best scores are: opt bits E(85289)
NP_001257330 (OMIM: 180246) retinoic acid receptor ( 537) 3792 266.6 1.3e-70
NP_068811 (OMIM: 180246) retinoic acid receptor RX ( 533) 3752 264.0 8.3e-70
XP_016866665 (OMIM: 180246) PREDICTED: retinoic ac ( 414) 2869 205.3 3e-52
XP_005249335 (OMIM: 180246) PREDICTED: retinoic ac ( 441) 2587 186.6 1.4e-46
XP_011513098 (OMIM: 180246) PREDICTED: retinoic ac ( 420) 2350 170.9 7.1e-42
NP_001278918 (OMIM: 180246) retinoic acid receptor ( 347) 2327 169.3 1.8e-41
NP_002948 (OMIM: 180245) retinoic acid receptor RX ( 462) 2119 155.6 3.1e-37
NP_001278849 (OMIM: 180245) retinoic acid receptor ( 435) 2110 154.9 4.5e-37
NP_001278850 (OMIM: 180245) retinoic acid receptor ( 365) 1989 146.8 1e-34
NP_008848 (OMIM: 180247) retinoic acid receptor RX ( 463) 1785 133.4 1.5e-30
NP_001243499 (OMIM: 180247) retinoic acid receptor ( 340) 1728 129.5 1.6e-29
NP_001243500 (OMIM: 180247) retinoic acid receptor ( 340) 1728 129.5 1.6e-29
NP_066285 (OMIM: 107773,615779) COUP transcription ( 414) 975 79.6 2.1e-14
NP_005645 (OMIM: 132890,615722) COUP transcription ( 423) 973 79.5 2.3e-14
NP_001277145 (OMIM: 180220,615524) retinoic acid r ( 455) 734 63.6 1.5e-09
NP_001230659 (OMIM: 180190) retinoic acid receptor ( 382) 711 62.0 3.7e-09
NP_000957 (OMIM: 180190) retinoic acid receptor ga ( 454) 712 62.2 4e-09
XP_005257611 (OMIM: 180240,612376) PREDICTED: reti ( 462) 712 62.2 4e-09
NP_001138773 (OMIM: 180240,612376) retinoic acid r ( 462) 712 62.2 4e-09
NP_000955 (OMIM: 180240,612376) retinoic acid rece ( 462) 712 62.2 4e-09
XP_011523397 (OMIM: 180240,612376) PREDICTED: reti ( 462) 712 62.2 4e-09
XP_005257610 (OMIM: 180240,612376) PREDICTED: reti ( 462) 712 62.2 4e-09
NP_001036193 (OMIM: 180190) retinoic acid receptor ( 443) 711 62.1 4.1e-09
NP_001230442 (OMIM: 602969) estrogen-related recep ( 435) 710 62.0 4.2e-09
XP_016856130 (OMIM: 602969) PREDICTED: estrogen-re ( 435) 710 62.0 4.2e-09
NP_001230444 (OMIM: 602969) estrogen-related recep ( 435) 710 62.0 4.2e-09
XP_016856134 (OMIM: 602969) PREDICTED: estrogen-re ( 435) 710 62.0 4.2e-09
NP_001127757 (OMIM: 602969) estrogen-related recep ( 435) 710 62.0 4.2e-09
XP_016856132 (OMIM: 602969) PREDICTED: estrogen-re ( 435) 710 62.0 4.2e-09
XP_016856138 (OMIM: 602969) PREDICTED: estrogen-re ( 435) 710 62.0 4.2e-09
NP_996318 (OMIM: 602969) estrogen-related receptor ( 435) 710 62.0 4.2e-09
NP_001230443 (OMIM: 602969) estrogen-related recep ( 435) 710 62.0 4.2e-09
NP_001230448 (OMIM: 602969) estrogen-related recep ( 435) 710 62.0 4.2e-09
XP_016856128 (OMIM: 602969) PREDICTED: estrogen-re ( 435) 710 62.0 4.2e-09
NP_001230440 (OMIM: 602969) estrogen-related recep ( 435) 710 62.0 4.2e-09
XP_016856133 (OMIM: 602969) PREDICTED: estrogen-re ( 435) 710 62.0 4.2e-09
XP_016856129 (OMIM: 602969) PREDICTED: estrogen-re ( 435) 710 62.0 4.2e-09
XP_016856131 (OMIM: 602969) PREDICTED: estrogen-re ( 435) 710 62.0 4.2e-09
XP_016856137 (OMIM: 602969) PREDICTED: estrogen-re ( 435) 710 62.0 4.2e-09
NP_996317 (OMIM: 602969) estrogen-related receptor ( 435) 710 62.0 4.2e-09
XP_016856135 (OMIM: 602969) PREDICTED: estrogen-re ( 435) 710 62.0 4.2e-09
NP_001230439 (OMIM: 602969) estrogen-related recep ( 435) 710 62.0 4.2e-09
XP_016856127 (OMIM: 602969) PREDICTED: estrogen-re ( 435) 710 62.0 4.2e-09
NP_001230441 (OMIM: 602969) estrogen-related recep ( 435) 710 62.0 4.2e-09
NP_001230438 (OMIM: 602969) estrogen-related recep ( 435) 710 62.0 4.2e-09
XP_016856136 (OMIM: 602969) PREDICTED: estrogen-re ( 435) 710 62.0 4.2e-09
NP_001429 (OMIM: 602969) estrogen-related receptor ( 458) 710 62.0 4.4e-09
XP_016856116 (OMIM: 602969) PREDICTED: estrogen-re ( 463) 710 62.1 4.4e-09
XP_016856115 (OMIM: 602969) PREDICTED: estrogen-re ( 463) 710 62.1 4.4e-09
XP_011507568 (OMIM: 602969) PREDICTED: estrogen-re ( 470) 710 62.1 4.5e-09
>>NP_001257330 (OMIM: 180246) retinoic acid receptor RXR (537 aa)
initn: 3792 init1: 3792 opt: 3792 Z-score: 1388.5 bits: 266.6 E(85289): 1.3e-70
Smith-Waterman score: 3792; 100.0% identity (100.0% similar) in 537 aa overlap (1-537:1-537)
10 20 30 40 50 60
pF1KB4 MSWAARPPFLPQRHAAGQCGPVGVRKEMHCGVASRWRRRRPWLDPAAAAAAAVAGGEQQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSWAARPPFLPQRHAAGQCGPVGVRKEMHCGVASRWRRRRPWLDPAAAAAAAVAGGEQQT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 PEPEPGEAGRDGMGDSGRDSRSPDSSSPNPLPQGVPPPSPPGPPLPPSTAPSLGGSGAPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PEPEPGEAGRDGMGDSGRDSRSPDSSSPNPLPQGVPPPSPPGPPLPPSTAPSLGGSGAPP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 PPPMPPPPLGSPFPVISSSMGSPGLPPPAPPGFSGPVSSPQINSTVSLPGGGSGPPEDVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPPMPPPPLGSPFPVISSSMGSPGLPPPAPPGFSGPVSSPQINSTVSLPGGGSGPPEDVK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 PPVLGVRGLHCPPPPGGPGAGKRLCAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLTYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPVLGVRGLHCPPPPGGPGAGKRLCAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLTYS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 CRDNKDCTVDKRQRNRCQYCRYQKCLATGMKREAVQEERQRGKDKDGDGEGAGGAPEEMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CRDNKDCTVDKRQRNRCQYCRYQKCLATGMKREAVQEERQRGKDKDGDGEGAGGAPEEMP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 VDRILEAELAVEQKSDQGVEGPGGTGGSGSSPNDPVTNICQAADKQLFTLVEWAKRIPHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VDRILEAELAVEQKSDQGVEGPGGTGGSGSSPNDPVTNICQAADKQLFTLVEWAKRIPHF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 SSLPLDDQVILLRAGWNELLIASFSHRSIDVRDGILLATGLHVHRNSAHSAGVGAIFDRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSLPLDDQVILLRAGWNELLIASFSHRSIDVRDGILLATGLHVHRNSAHSAGVGAIFDRS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 LSRVLTELVSKMRDMRMDKTELGCLRAIILFNPDAKGLSNPSEVEVLREKVYASLETYCK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSRVLTELVSKMRDMRMDKTELGCLRAIILFNPDAKGLSNPSEVEVLREKVYASLETYCK
430 440 450 460 470 480
490 500 510 520 530
pF1KB4 QKYPEQQGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQLA
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QKYPEQQGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQLA
490 500 510 520 530
>>NP_068811 (OMIM: 180246) retinoic acid receptor RXR-be (533 aa)
initn: 3037 init1: 3037 opt: 3752 Z-score: 1374.2 bits: 264.0 E(85289): 8.3e-70
Smith-Waterman score: 3752; 99.3% identity (99.3% similar) in 537 aa overlap (1-537:1-533)
10 20 30 40 50 60
pF1KB4 MSWAARPPFLPQRHAAGQCGPVGVRKEMHCGVASRWRRRRPWLDPAAAAAAAVAGGEQQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 MSWAARPPFLPQRHAAGQCGPVGVRKEMHCGVASRWRRRRPWLDPAAAAAAAVAGGEQQT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 PEPEPGEAGRDGMGDSGRDSRSPDSSSPNPLPQGVPPPSPPGPPLPPSTAPSLGGSGAPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 PEPEPGEAGRDGMGDSGRDSRSPDSSSPNPLPQGVPPPSPPGPPLPPSTAPSLGGSGAPP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 PPPMPPPPLGSPFPVISSSMGSPGLPPPAPPGFSGPVSSPQINSTVSLPGGGSGPPEDVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 PPPMPPPPLGSPFPVISSSMGSPGLPPPAPPGFSGPVSSPQINSTVSLPGGGSGPPEDVK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 PPVLGVRGLHCPPPPGGPGAGKRLCAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLTYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 PPVLGVRGLHCPPPPGGPGAGKRLCAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLTYS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 CRDNKDCTVDKRQRNRCQYCRYQKCLATGMKREAVQEERQRGKDKDGDGEGAGGAPEEMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 CRDNKDCTVDKRQRNRCQYCRYQKCLATGMKREAVQEERQRGKDKDGDGEGAGGAPEEMP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 VDRILEAELAVEQKSDQGVEGPGGTGGSGSSPNDPVTNICQAADKQLFTLVEWAKRIPHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 VDRILEAELAVEQKSDQGVEGPGGTGGSGSSPNDPVTNICQAADKQLFTLVEWAKRIPHF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 SSLPLDDQVILLRAGWNELLIASFSHRSIDVRDGILLATGLHVHRNSAHSAGVGAIFDRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 SSLPLDDQVILLRAGWNELLIASFSHRSIDVRDGILLATGLHVHRNSAHSAGVGAIFD--
370 380 390 400 410
430 440 450 460 470 480
pF1KB4 LSRVLTELVSKMRDMRMDKTELGCLRAIILFNPDAKGLSNPSEVEVLREKVYASLETYCK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 --RVLTELVSKMRDMRMDKTELGCLRAIILFNPDAKGLSNPSEVEVLREKVYASLETYCK
420 430 440 450 460 470
490 500 510 520 530
pF1KB4 QKYPEQQGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQLA
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 QKYPEQQGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQLA
480 490 500 510 520 530
>>XP_016866665 (OMIM: 180246) PREDICTED: retinoic acid r (414 aa)
initn: 2869 init1: 2869 opt: 2869 Z-score: 1059.0 bits: 205.3 E(85289): 3e-52
Smith-Waterman score: 2869; 100.0% identity (100.0% similar) in 414 aa overlap (124-537:1-414)
100 110 120 130 140 150
pF1KB4 GVPPPSPPGPPLPPSTAPSLGGSGAPPPPPMPPPPLGSPFPVISSSMGSPGLPPPAPPGF
::::::::::::::::::::::::::::::
XP_016 MPPPPLGSPFPVISSSMGSPGLPPPAPPGF
10 20 30
160 170 180 190 200 210
pF1KB4 SGPVSSPQINSTVSLPGGGSGPPEDVKPPVLGVRGLHCPPPPGGPGAGKRLCAICGDRSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGPVSSPQINSTVSLPGGGSGPPEDVKPPVLGVRGLHCPPPPGGPGAGKRLCAICGDRSS
40 50 60 70 80 90
220 230 240 250 260 270
pF1KB4 GKHYGVYSCEGCKGFFKRTIRKDLTYSCRDNKDCTVDKRQRNRCQYCRYQKCLATGMKRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GKHYGVYSCEGCKGFFKRTIRKDLTYSCRDNKDCTVDKRQRNRCQYCRYQKCLATGMKRE
100 110 120 130 140 150
280 290 300 310 320 330
pF1KB4 AVQEERQRGKDKDGDGEGAGGAPEEMPVDRILEAELAVEQKSDQGVEGPGGTGGSGSSPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVQEERQRGKDKDGDGEGAGGAPEEMPVDRILEAELAVEQKSDQGVEGPGGTGGSGSSPN
160 170 180 190 200 210
340 350 360 370 380 390
pF1KB4 DPVTNICQAADKQLFTLVEWAKRIPHFSSLPLDDQVILLRAGWNELLIASFSHRSIDVRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DPVTNICQAADKQLFTLVEWAKRIPHFSSLPLDDQVILLRAGWNELLIASFSHRSIDVRD
220 230 240 250 260 270
400 410 420 430 440 450
pF1KB4 GILLATGLHVHRNSAHSAGVGAIFDRSLSRVLTELVSKMRDMRMDKTELGCLRAIILFNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GILLATGLHVHRNSAHSAGVGAIFDRSLSRVLTELVSKMRDMRMDKTELGCLRAIILFNP
280 290 300 310 320 330
460 470 480 490 500 510
pF1KB4 DAKGLSNPSEVEVLREKVYASLETYCKQKYPEQQGRFAKLLLRLPALRSIGLKCLEHLFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DAKGLSNPSEVEVLREKVYASLETYCKQKYPEQQGRFAKLLLRLPALRSIGLKCLEHLFF
340 350 360 370 380 390
520 530
pF1KB4 FKLIGDTPIDTFLMEMLEAPHQLA
::::::::::::::::::::::::
XP_016 FKLIGDTPIDTFLMEMLEAPHQLA
400 410
>>XP_005249335 (OMIM: 180246) PREDICTED: retinoic acid r (441 aa)
initn: 2582 init1: 2582 opt: 2587 Z-score: 957.5 bits: 186.6 E(85289): 1.4e-46
Smith-Waterman score: 2587; 98.2% identity (99.2% similar) in 384 aa overlap (154-537:58-441)
130 140 150 160 170 180
pF1KB4 MPPPPLGSPFPVISSSMGSPGLPPPAPPGFSGPVSSPQINSTVSLPGGGSGPPEDVKPPV
.: ... ::::::::::::::::::::::
XP_005 PGWIPQRRRRRRWQAENNKPRSRSQGRLDGTGWATAGGINSTVSLPGGGSGPPEDVKPPV
30 40 50 60 70 80
190 200 210 220 230 240
pF1KB4 LGVRGLHCPPPPGGPGAGKRLCAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLTYSCRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LGVRGLHCPPPPGGPGAGKRLCAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLTYSCRD
90 100 110 120 130 140
250 260 270 280 290 300
pF1KB4 NKDCTVDKRQRNRCQYCRYQKCLATGMKREAVQEERQRGKDKDGDGEGAGGAPEEMPVDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NKDCTVDKRQRNRCQYCRYQKCLATGMKREAVQEERQRGKDKDGDGEGAGGAPEEMPVDR
150 160 170 180 190 200
310 320 330 340 350 360
pF1KB4 ILEAELAVEQKSDQGVEGPGGTGGSGSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ILEAELAVEQKSDQGVEGPGGTGGSGSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSSL
210 220 230 240 250 260
370 380 390 400 410 420
pF1KB4 PLDDQVILLRAGWNELLIASFSHRSIDVRDGILLATGLHVHRNSAHSAGVGAIFDRSLSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PLDDQVILLRAGWNELLIASFSHRSIDVRDGILLATGLHVHRNSAHSAGVGAIFDRSLSR
270 280 290 300 310 320
430 440 450 460 470 480
pF1KB4 VLTELVSKMRDMRMDKTELGCLRAIILFNPDAKGLSNPSEVEVLREKVYASLETYCKQKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VLTELVSKMRDMRMDKTELGCLRAIILFNPDAKGLSNPSEVEVLREKVYASLETYCKQKY
330 340 350 360 370 380
490 500 510 520 530
pF1KB4 PEQQGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PEQQGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQLA
390 400 410 420 430 440
>>XP_011513098 (OMIM: 180246) PREDICTED: retinoic acid r (420 aa)
initn: 2889 init1: 2327 opt: 2350 Z-score: 872.8 bits: 170.9 E(85289): 7.1e-42
Smith-Waterman score: 2659; 78.2% identity (78.2% similar) in 537 aa overlap (1-537:1-420)
10 20 30 40 50 60
pF1KB4 MSWAARPPFLPQRHAAGQCGPVGVRKEMHCGVASRWRRRRPWLDPAAAAAAAVAGGEQQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSWAARPPFLPQRHAAGQCGPVGVRKEMHCGVASRWRRRRPWLDPAAAAAAAVAGGEQQT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 PEPEPGEAGRDGMGDSGRDSRSPDSSSPNPLPQGVPPPSPPGPPLPPSTAPSLGGSGAPP
::::::::::::::::::
XP_011 PEPEPGEAGRDGMGDSGR------------------------------------------
70
130 140 150 160 170 180
pF1KB4 PPPMPPPPLGSPFPVISSSMGSPGLPPPAPPGFSGPVSSPQINSTVSLPGGGSGPPEDVK
XP_011 ------------------------------------------------------------
190 200 210 220 230 240
pF1KB4 PPVLGVRGLHCPPPPGGPGAGKRLCAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLTYS
:::::::::::::::::::::::::::::::::::::::::::::
XP_011 ---------------GGPGAGKRLCAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLTYS
80 90 100 110 120
250 260 270 280 290 300
pF1KB4 CRDNKDCTVDKRQRNRCQYCRYQKCLATGMKREAVQEERQRGKDKDGDGEGAGGAPEEMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CRDNKDCTVDKRQRNRCQYCRYQKCLATGMKREAVQEERQRGKDKDGDGEGAGGAPEEMP
130 140 150 160 170 180
310 320 330 340 350 360
pF1KB4 VDRILEAELAVEQKSDQGVEGPGGTGGSGSSPNDPVTNICQAADKQLFTLVEWAKRIPHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VDRILEAELAVEQKSDQGVEGPGGTGGSGSSPNDPVTNICQAADKQLFTLVEWAKRIPHF
190 200 210 220 230 240
370 380 390 400 410 420
pF1KB4 SSLPLDDQVILLRAGWNELLIASFSHRSIDVRDGILLATGLHVHRNSAHSAGVGAIFDRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSLPLDDQVILLRAGWNELLIASFSHRSIDVRDGILLATGLHVHRNSAHSAGVGAIFDRS
250 260 270 280 290 300
430 440 450 460 470 480
pF1KB4 LSRVLTELVSKMRDMRMDKTELGCLRAIILFNPDAKGLSNPSEVEVLREKVYASLETYCK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSRVLTELVSKMRDMRMDKTELGCLRAIILFNPDAKGLSNPSEVEVLREKVYASLETYCK
310 320 330 340 350 360
490 500 510 520 530
pF1KB4 QKYPEQQGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQLA
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QKYPEQQGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQLA
370 380 390 400 410 420
>>NP_001278918 (OMIM: 180246) retinoic acid receptor RXR (347 aa)
initn: 2327 init1: 2327 opt: 2327 Z-score: 865.6 bits: 169.3 E(85289): 1.8e-41
Smith-Waterman score: 2327; 100.0% identity (100.0% similar) in 342 aa overlap (196-537:6-347)
170 180 190 200 210 220
pF1KB4 VSLPGGGSGPPEDVKPPVLGVRGLHCPPPPGGPGAGKRLCAICGDRSSGKHYGVYSCEGC
::::::::::::::::::::::::::::::
NP_001 MRECGGGPGAGKRLCAICGDRSSGKHYGVYSCEGC
10 20 30
230 240 250 260 270 280
pF1KB4 KGFFKRTIRKDLTYSCRDNKDCTVDKRQRNRCQYCRYQKCLATGMKREAVQEERQRGKDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KGFFKRTIRKDLTYSCRDNKDCTVDKRQRNRCQYCRYQKCLATGMKREAVQEERQRGKDK
40 50 60 70 80 90
290 300 310 320 330 340
pF1KB4 DGDGEGAGGAPEEMPVDRILEAELAVEQKSDQGVEGPGGTGGSGSSPNDPVTNICQAADK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DGDGEGAGGAPEEMPVDRILEAELAVEQKSDQGVEGPGGTGGSGSSPNDPVTNICQAADK
100 110 120 130 140 150
350 360 370 380 390 400
pF1KB4 QLFTLVEWAKRIPHFSSLPLDDQVILLRAGWNELLIASFSHRSIDVRDGILLATGLHVHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLFTLVEWAKRIPHFSSLPLDDQVILLRAGWNELLIASFSHRSIDVRDGILLATGLHVHR
160 170 180 190 200 210
410 420 430 440 450 460
pF1KB4 NSAHSAGVGAIFDRSLSRVLTELVSKMRDMRMDKTELGCLRAIILFNPDAKGLSNPSEVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NSAHSAGVGAIFDRSLSRVLTELVSKMRDMRMDKTELGCLRAIILFNPDAKGLSNPSEVE
220 230 240 250 260 270
470 480 490 500 510 520
pF1KB4 VLREKVYASLETYCKQKYPEQQGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLREKVYASLETYCKQKYPEQQGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTF
280 290 300 310 320 330
530
pF1KB4 LMEMLEAPHQLA
::::::::::::
NP_001 LMEMLEAPHQLA
340
>>NP_002948 (OMIM: 180245) retinoic acid receptor RXR-al (462 aa)
initn: 2099 init1: 707 opt: 2119 Z-score: 789.4 bits: 155.6 E(85289): 3.1e-37
Smith-Waterman score: 2119; 71.4% identity (83.7% similar) in 465 aa overlap (80-536:12-461)
50 60 70 80 90 100
pF1KB4 AAAVAGGEQQTPEPEPGEAGRDGMGDSGRDSRSPDSSSPNPLPQGVPPPSPPGPPLPPST
: . .:: .: .: : .: : ::
NP_002 MDTKHFLPLDFSTQVNSSLTSPTGRG----SMAAPSLHPSL
10 20 30
110 120 130 140 150 160
pF1KB4 APSLGGSGAPPPP----PMPPPPLGSPFPVISSSMGSPGLPPPAPPGFSGPVSSPQINST
.:..:. : : : .: :: :::: :: .. :. : .. ..:::..:
NP_002 GPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSP
40 50 60 70 80 90
170 180 190 200 210 220
pF1KB4 VSLPGGGSGPPEDVKPPVLGVRG-LHCPPPPGGPGAG--KRLCAICGDRSSGKHYGVYSC
.. : ..: ::.::: ::. : :. : :.: :. :..::::::::::::::::::
NP_002 MN-PVSSS---EDIKPP-LGLNGVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSC
100 110 120 130 140 150
230 240 250 260 270 280
pF1KB4 EGCKGFFKRTIRKDLTYSCRDNKDCTVDKRQRNRCQYCRYQKCLATGMKREAVQEERQRG
::::::::::.::::::.::::::: .:::::::::::::::::: ::::::::::::::
NP_002 EGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRG
160 170 180 190 200 210
290 300 310 320 330 340
pF1KB4 KDKD-GDGEGAGGAPEEMPVDRILEAELAVEQKSDQGVEGPGGTGGSGSSPNDPVTNICQ
::.. .. :....: :.:::.:::::::::: :.. ::. . : . ::::::::::::
NP_002 KDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEA--NMGLNPSSPNDPVTNICQ
220 230 240 250 260 270
350 360 370 380 390 400
pF1KB4 AADKQLFTLVEWAKRIPHFSSLPLDDQVILLRAGWNELLIASFSHRSIDVRDGILLATGL
:::::::::::::::::::: ::::::::::::::::::::::::::: :.:::::::::
NP_002 AADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGL
280 290 300 310 320 330
410 420 430 440 450 460
pF1KB4 HVHRNSAHSAGVGAIFDRSLSRVLTELVSKMRDMRMDKTELGCLRAIILFNPDAKGLSNP
:::::::::::::::::: ::::::::::::.::::::::::::.:::::.::::::
NP_002 HVHRNSAHSAGVGAIFDR----VLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNP
340 350 360 370 380
470 480 490 500 510 520
pF1KB4 SEVEVLREKVYASLETYCKQKYPEQQGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTP
.:::.::::::::::.:::.::::: ::::::::::::::::::::::::::::::::::
NP_002 AEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTP
390 400 410 420 430 440
530
pF1KB4 IDTFLMEMLEAPHQLA
::::::::::::::.
NP_002 IDTFLMEMLEAPHQMT
450 460
>>NP_001278849 (OMIM: 180245) retinoic acid receptor RXR (435 aa)
initn: 2099 init1: 707 opt: 2110 Z-score: 786.5 bits: 154.9 E(85289): 4.5e-37
Smith-Waterman score: 2110; 73.8% identity (85.5% similar) in 442 aa overlap (103-536:4-434)
80 90 100 110 120
pF1KB4 MGDSGRDSRSPDSSSPNPLPQGVPPPSPPGPPLPPSTAPSLGGSGAPPPP----PMPPPP
: : :: .:..:. : : :
NP_001 MAAPSLHPSLGPGIGSPGQLHSPISTLSSPING
10 20 30
130 140 150 160 170 180
pF1KB4 LGSPFPVISSSMGSPGLPPPAPPGFSGPVSSPQINSTVSLPGGGSGPPEDVKPPVLGVRG
.: :: :::: :: .. :. : .. ..:::..: .. : ..: ::.::: ::. :
NP_001 MGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMN-PVSSS---EDIKPP-LGLNG
40 50 60 70 80
190 200 210 220 230 240
pF1KB4 -LHCPPPPGGPGAG--KRLCAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLTYSCRDNK
:. : :.: :. :..::::::::::::::::::::::::::::.::::::.:::::
NP_001 VLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNK
90 100 110 120 130 140
250 260 270 280 290 300
pF1KB4 DCTVDKRQRNRCQYCRYQKCLATGMKREAVQEERQRGKDKD-GDGEGAGGAPEEMPVDRI
:: .:::::::::::::::::: ::::::::::::::::.. .. :....: :.:::.::
NP_001 DCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERI
150 160 170 180 190 200
310 320 330 340 350 360
pF1KB4 LEAELAVEQKSDQGVEGPGGTGGSGSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSSLP
:::::::: :.. :: .. : . :::::::::::::::::::::::::::::::: ::
NP_001 LEAELAVEPKTETYVE--ANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELP
210 220 230 240 250 260
370 380 390 400 410 420
pF1KB4 LDDQVILLRAGWNELLIASFSHRSIDVRDGILLATGLHVHRNSAHSAGVGAIFDRSLSRV
::::::::::::::::::::::::: :.::::::::::::::::::::::::::: :
NP_001 LDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDR----V
270 280 290 300 310 320
430 440 450 460 470 480
pF1KB4 LTELVSKMRDMRMDKTELGCLRAIILFNPDAKGLSNPSEVEVLREKVYASLETYCKQKYP
:::::::::::.::::::::::::.:::::.::::::.:::.::::::::::.:::.:::
NP_001 LTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYP
330 340 350 360 370 380
490 500 510 520 530
pF1KB4 EQQGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQLA
:: ::::::::::::::::::::::::::::::::::::::::::::::::.
NP_001 EQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT
390 400 410 420 430
>>NP_001278850 (OMIM: 180245) retinoic acid receptor RXR (365 aa)
initn: 1989 init1: 707 opt: 1989 Z-score: 744.1 bits: 146.8 E(85289): 1e-34
Smith-Waterman score: 1989; 82.4% identity (91.8% similar) in 364 aa overlap (177-536:8-364)
150 160 170 180 190 200
pF1KB4 PPAPPGFSGPVSSPQINSTVSLPGGGSGPPEDVKPPVLGVRG-LHCPPPPGGPGAG--KR
::.::: ::. : :. : :.: :. :.
NP_001 MNPVSSSEDIKPP-LGLNGVLKVPAHPSGNMASFTKH
10 20 30
210 220 230 240 250 260
pF1KB4 LCAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLTYSCRDNKDCTVDKRQRNRCQYCRYQ
.::::::::::::::::::::::::::::.::::::.::::::: .::::::::::::::
NP_001 ICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQ
40 50 60 70 80 90
270 280 290 300 310 320
pF1KB4 KCLATGMKREAVQEERQRGKDKD-GDGEGAGGAPEEMPVDRILEAELAVEQKSDQGVEGP
:::: ::::::::::::::::.. .. :....: :.:::.:::::::::: :.. ::
NP_001 KCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVE--
100 110 120 130 140 150
330 340 350 360 370 380
pF1KB4 GGTGGSGSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSSLPLDDQVILLRAGWNELLIA
.. : . :::::::::::::::::::::::::::::::: ::::::::::::::::::::
NP_001 ANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIA
160 170 180 190 200 210
390 400 410 420 430 440
pF1KB4 SFSHRSIDVRDGILLATGLHVHRNSAHSAGVGAIFDRSLSRVLTELVSKMRDMRMDKTEL
::::::: :.::::::::::::::::::::::::::: ::::::::::::.::::::
NP_001 SFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDR----VLTELVSKMRDMQMDKTEL
220 230 240 250 260 270
450 460 470 480 490 500
pF1KB4 GCLRAIILFNPDAKGLSNPSEVEVLREKVYASLETYCKQKYPEQQGRFAKLLLRLPALRS
::::::.:::::.::::::.:::.::::::::::.:::.::::: :::::::::::::::
NP_001 GCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRS
280 290 300 310 320 330
510 520 530
pF1KB4 IGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQLA
:::::::::::::::::::::::::::::::::.
NP_001 IGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT
340 350 360
>>NP_008848 (OMIM: 180247) retinoic acid receptor RXR-ga (463 aa)
initn: 1938 init1: 678 opt: 1785 Z-score: 669.5 bits: 133.4 E(85289): 1.5e-30
Smith-Waterman score: 1966; 66.9% identity (81.1% similar) in 477 aa overlap (68-536:13-462)
40 50 60 70 80 90
pF1KB4 RRRPWLDPAAAAAAAVAGGEQQTPEPEPGEAGRDGM-GDSGRDSRSPDSSSPNPLPQGVP
:: : : .: : ::... : : :
NP_008 MYGNYSHFMKFPAGYGGSPGHTGSTSMSPSAA----LSTGKP
10 20 30
100 110 120 130 140 150
pF1KB4 PPSPPGPPLPPSTAP-SLGGSGAPPPPPMPPPPLGSPFPVISSSMGSPGLPPPAPPGFS-
: :. : .:: .:.. :.: ::::. ::.:.:: :. ::::..
NP_008 MDSHPSYTDTPVSAPRTLSAVGTP------LNALGSPYRVITSAMGPPSGALAAPPGINL
40 50 60 70 80 90
160 170 180 190 200 210
pF1KB4 -GPVSSPQINSTVSLPGGGSGPPEDVKP-PVL-GVRGLHCPPPPGGPGAG-KRLCAICGD
.: :: :.: . :. .. ::.:: : : :. ... : .::. :..::::::
NP_008 VAPPSS-QLNVVNSVSSS-----EDIKPLPGLPGIGNMNYPST--SPGSLVKHICAICGD
100 110 120 130 140
220 230 240 250 260 270
pF1KB4 RSSGKHYGVYSCEGCKGFFKRTIRKDLTYSCRDNKDCTVDKRQRNRCQYCRYQKCLATGM
::::::::::::::::::::::::::: :.::::::: .:::::::::::::::::. ::
NP_008 RSSGKHYGVYSCEGCKGFFKRTIRKDLIYTCRDNKDCLIDKRQRNRCQYCRYQKCLVMGM
150 160 170 180 190 200
280 290 300 310 320
pF1KB4 KREAVQEERQRGKDK-DGDGEGAGGAPEEMPVDRILEAELAVEQKSDQGVEGPGGTGGSG
:::::::::::.... ....: : .. :.:::.:::::::::: :... : .
NP_008 KREAVQEERQRSRERAESEAECATSGHEDMPVERILEAELAVEPKTES-----YGDMNME
210 220 230 240 250
330 340 350 360 370 380
pF1KB4 SSPNDPVTNICQAADKQLFTLVEWAKRIPHFSSLPLDDQVILLRAGWNELLIASFSHRSI
.: ::::::::.::::::::::::::::::::.: :.::::::::::::::::::::::.
NP_008 NSTNDPVTNICHAADKQLFTLVEWAKRIPHFSDLTLEDQVILLRAGWNELLIASFSHRSV
260 270 280 290 300 310
390 400 410 420 430 440
pF1KB4 DVRDGILLATGLHVHRNSAHSAGVGAIFDRSLSRVLTELVSKMRDMRMDKTELGCLRAII
.:.:::::::::::::.::::::::.:::: :::::::::.::.:::.::::::::.
NP_008 SVQDGILLATGLHVHRSSAHSAGVGSIFDR----VLTELVSKMKDMQMDKSELGCLRAIV
320 330 340 350 360 370
450 460 470 480 490 500
pF1KB4 LFNPDAKGLSNPSEVEVLREKVYASLETYCKQKYPEQQGRFAKLLLRLPALRSIGLKCLE
::::::::::::::::.:::::::.::.: ::::::: ::::::::::::::::::::::
NP_008 LFNPDAKGLSNPSEVETLREKVYATLEAYTKQKYPEQPGRFAKLLLRLPALRSIGLKCLE
380 390 400 410 420 430
510 520 530
pF1KB4 HLFFFKLIGDTPIDTFLMEMLEAPHQLA
::::::::::::::::::::::.: :.
NP_008 HLFFFKLIGDTPIDTFLMEMLETPLQIT
440 450 460
537 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 14:18:27 2016 done: Thu Nov 3 14:18:29 2016
Total Scan time: 9.930 Total Display time: 0.070
Function used was FASTA [36.3.4 Apr, 2011]