FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB4066, 424 aa
1>>>pF1KB4066 424 - 424 aa - 424 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.2585+/-0.000864; mu= 12.6224+/- 0.052
mean_var=79.3247+/-16.687, 0's: 0 Z-trim(107.6): 54 B-trim: 376 in 1/50
Lambda= 0.144003
statistics sampled from 9661 (9704) to 9661 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.678), E-opt: 0.2 (0.298), width: 16
Scan time: 3.230
The best scores are: opt bits E(32554)
CCDS3916.1 SKP2 gene_id:6502|Hs108|chr5 ( 424) 2848 601.2 6e-172
CCDS3915.1 SKP2 gene_id:6502|Hs108|chr5 ( 410) 2375 503.0 2.2e-142
CCDS58944.1 SKP2 gene_id:6502|Hs108|chr5 ( 210) 1329 285.5 3.2e-77
CCDS54560.1 FBXL2 gene_id:25827|Hs108|chr3 ( 355) 293 70.4 3.2e-12
>>CCDS3916.1 SKP2 gene_id:6502|Hs108|chr5 (424 aa)
initn: 2848 init1: 2848 opt: 2848 Z-score: 3200.4 bits: 601.2 E(32554): 6e-172
Smith-Waterman score: 2848; 100.0% identity (100.0% similar) in 424 aa overlap (1-424:1-424)
10 20 30 40 50 60
pF1KB4 MHRKHLQEIPDLSSNVATSFTWGWDSSKTSELLSGMGVSALEKEEPDSENIPQELLSNLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS39 MHRKHLQEIPDLSSNVATSFTWGWDSSKTSELLSGMGVSALEKEEPDSENIPQELLSNLG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 HPESPPRKRLKSKGSDKDFVIVRRPKLNRENFPGVSWDSLPDELLLGIFSCLCLPELLKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS39 HPESPPRKRLKSKGSDKDFVIVRRPKLNRENFPGVSWDSLPDELLLGIFSCLCLPELLKV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 SGVCKRWYRLASDESLWQTLDLTGKNLHPDVTGRLLSQGVIAFRCPRSFMDQPLAEHFSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS39 SGVCKRWYRLASDESLWQTLDLTGKNLHPDVTGRLLSQGVIAFRCPRSFMDQPLAEHFSP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 FRVQHMDLSNSVIEVSTLHGILSQCSKLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS39 FRVQHMDLSNSVIEVSTLHGILSQCSKLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 SGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS39 SGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 DLSTLVRRCPNLVHLDLSDSVMLKNDCFQEFFQLNYLQHLSLSRCYDIIPETLLELGEIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS39 DLSTLVRRCPNLVHLDLSDSVMLKNDCFQEFFQLNYLQHLSLSRCYDIIPETLLELGEIP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 TLKTLQVFGIVPDGTLQLLKEALPHLQINCSHFTTIARPTIGNKKNQEIWGIKCRLTLQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS39 TLKTLQVFGIVPDGTLQLLKEALPHLQINCSHFTTIARPTIGNKKNQEIWGIKCRLTLQK
370 380 390 400 410 420
pF1KB4 PSCL
::::
CCDS39 PSCL
>>CCDS3915.1 SKP2 gene_id:6502|Hs108|chr5 (410 aa)
initn: 2375 init1: 2375 opt: 2375 Z-score: 2669.6 bits: 503.0 E(32554): 2.2e-142
Smith-Waterman score: 2375; 100.0% identity (100.0% similar) in 354 aa overlap (1-354:1-354)
10 20 30 40 50 60
pF1KB4 MHRKHLQEIPDLSSNVATSFTWGWDSSKTSELLSGMGVSALEKEEPDSENIPQELLSNLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS39 MHRKHLQEIPDLSSNVATSFTWGWDSSKTSELLSGMGVSALEKEEPDSENIPQELLSNLG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 HPESPPRKRLKSKGSDKDFVIVRRPKLNRENFPGVSWDSLPDELLLGIFSCLCLPELLKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS39 HPESPPRKRLKSKGSDKDFVIVRRPKLNRENFPGVSWDSLPDELLLGIFSCLCLPELLKV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 SGVCKRWYRLASDESLWQTLDLTGKNLHPDVTGRLLSQGVIAFRCPRSFMDQPLAEHFSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS39 SGVCKRWYRLASDESLWQTLDLTGKNLHPDVTGRLLSQGVIAFRCPRSFMDQPLAEHFSP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 FRVQHMDLSNSVIEVSTLHGILSQCSKLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS39 FRVQHMDLSNSVIEVSTLHGILSQCSKLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 SGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS39 SGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 DLSTLVRRCPNLVHLDLSDSVMLKNDCFQEFFQLNYLQHLSLSRCYDIIPETLLELGEIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS39 DLSTLVRRCPNLVHLDLSDSVMLKNDCFQEFFQLNYLQHLSLSRCYDIIPETLLLVTRAG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 TLKTLQVFGIVPDGTLQLLKEALPHLQINCSHFTTIARPTIGNKKNQEIWGIKCRLTLQK
CCDS39 VRIRLDSDIGCPQTYRTSKLKSSHKLFCQHVRVICIFVCDFYFYRLVLKQ
370 380 390 400 410
>>CCDS58944.1 SKP2 gene_id:6502|Hs108|chr5 (210 aa)
initn: 1329 init1: 1329 opt: 1329 Z-score: 1499.9 bits: 285.5 E(32554): 3.2e-77
Smith-Waterman score: 1329; 99.5% identity (100.0% similar) in 201 aa overlap (224-424:10-210)
200 210 220 230 240 250
pF1KB4 EVSTLHGILSQCSKLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGCSGFSEFALQTLLS
.:::::::::::::::::::::::::::::
CCDS58 MDQPLAEHFSTLAKNSNLVRLNLSGCSGFSEFALQTLLS
10 20 30
260 270 280 290 300 310
pF1KB4 SCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKSDLSTLVRRCPNLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 SCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKSDLSTLVRRCPNLV
40 50 60 70 80 90
320 330 340 350 360 370
pF1KB4 HLDLSDSVMLKNDCFQEFFQLNYLQHLSLSRCYDIIPETLLELGEIPTLKTLQVFGIVPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 HLDLSDSVMLKNDCFQEFFQLNYLQHLSLSRCYDIIPETLLELGEIPTLKTLQVFGIVPD
100 110 120 130 140 150
380 390 400 410 420
pF1KB4 GTLQLLKEALPHLQINCSHFTTIARPTIGNKKNQEIWGIKCRLTLQKPSCL
:::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 GTLQLLKEALPHLQINCSHFTTIARPTIGNKKNQEIWGIKCRLTLQKPSCL
160 170 180 190 200 210
>>CCDS54560.1 FBXL2 gene_id:25827|Hs108|chr3 (355 aa)
initn: 362 init1: 116 opt: 293 Z-score: 333.0 bits: 70.4 E(32554): 3.2e-12
Smith-Waterman score: 296; 26.6% identity (55.5% similar) in 346 aa overlap (91-421:6-324)
70 80 90 100 110 120
pF1KB4 HPESPPRKRLKSKGSDKDFVIVRRPKLNRENFPGVSWDSLPDELLLGIFSCLCLPELLKV
: :. .:: :::: ::: : . : .
CCDS54 MVFSNNDEGLINKKLPKELLLRIFSFLDIVTLCRC
10 20 30
130 140 150 160 170 180
pF1KB4 SGVCKRWYRLASDESLWQTLDLTGKNLHPDVTGRLLSQGVIAFRCPRSFMDQPLAEHFSP
. . : : :: : : :: .:: :.. :: ::.. . :. :: .:.
CCDS54 AQISKAWNILALDGSNWQRIDLF--NFQTDVEGRVVEN--ISKRCG-GFL----------
40 50 60 70 80
190 200 210 220
pF1KB4 FRVQHMDLSNSV-IEVSTLHGILSQCSKLQNLSLEG-LRLSDPIVNTLAK----------
....: . . . :.:. . ..: ....:.:.: ...: .:..
CCDS54 ---RKLSLRGCIGVGDSSLKTFAQNCRNIEHLNLNGCTKITDSTCYSLSRFCSKLKHIQN
90 100 110 120 130
230 240 250 260 270 280
pF1KB4 -NSNLVRLNLSGCSGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQ
.:: :::..:: ... .. . .: ::. : :: : ..:. ..... .. :
CCDS54 YCHELVSLNLQSCSRITDEGVVQICRGCHRLQALCLSGCSNLTD--ASLTALGLNCPRLQ
140 150 160 170 180 190
290 300 310 320 330 340
pF1KB4 LNLSGYRKNLQKSDLSTLVRRCPNLVHLDLSDSVMLKNDCF-QEFFQLNYLQHLSLSRCY
. .. ..: . .. :.: : .: ..:: . ... .. . : .. :: ::::.:
CCDS54 ILEAARCSHLTDAGFTLLARNCHELEKMDLEECILITDSTLIQLSIHCPKLQALSLSHCE
200 210 220 230 240 250
350 360 370 380 390 400
pF1KB4 DIIPETLLELGEIPT-LKTLQVFGIVPDGTLQLLKEALPHLQINCSHFTTIARPTIGNKK
: . .:.:.. . :.:. . :. : . :: ::. :: . : . . .
CCDS54 LITDDGILHLSNSTCGHERLRVLEL--DNCLLITDVALEHLE-NCR---GLERLELYDCQ
260 270 280 290 300
410 420
pF1KB4 NQEIWGIKCRLTLQKPSCL
. ::: :. : :
CCDS54 QVTRAGIK-RMRAQLPHVKVHAYFAPVTPPTAVAGSGQRLCRCCVIL
310 320 330 340 350
424 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 21:23:26 2016 done: Thu Nov 3 21:23:27 2016
Total Scan time: 3.230 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]