FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB4066, 424 aa
1>>>pF1KB4066 424 - 424 aa - 424 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.3317+/-0.000375; mu= 12.3436+/- 0.023
mean_var=95.2915+/-19.473, 0's: 0 Z-trim(114.7): 88 B-trim: 0 in 0/52
Lambda= 0.131385
statistics sampled from 24657 (24747) to 24657 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.671), E-opt: 0.2 (0.29), width: 16
Scan time: 9.670
The best scores are: opt bits E(85289)
NP_005974 (OMIM: 601436) S-phase kinase-associated ( 424) 2848 550.3 3.4e-156
XP_011512384 (OMIM: 601436) PREDICTED: S-phase kin ( 358) 2375 460.6 2.8e-129
XP_011512383 (OMIM: 601436) PREDICTED: S-phase kin ( 379) 2375 460.6 3e-129
NP_116026 (OMIM: 601436) S-phase kinase-associated ( 410) 2375 460.6 3.2e-129
XP_011512385 (OMIM: 601436) PREDICTED: S-phase kin ( 255) 1688 330.3 3.4e-90
NP_001230049 (OMIM: 601436) S-phase kinase-associa ( 210) 1329 262.2 8.8e-70
XP_016865242 (OMIM: 601436) PREDICTED: S-phase kin ( 241) 1215 240.6 3.2e-63
NP_001165184 (OMIM: 605652) F-box/LRR-repeat prote ( 355) 293 66.0 1.8e-10
NP_001171835 (OMIM: 609086) F-box/LRR-repeat prote ( 404) 264 60.5 8.9e-09
XP_005257804 (OMIM: 609086) PREDICTED: F-box/LRR-r ( 441) 264 60.5 9.6e-09
XP_011512300 (OMIM: 605656) PREDICTED: F-box/LRR-r ( 444) 216 51.4 5.3e-06
NP_001265246 (OMIM: 605656) F-box/LRR-repeat prote ( 444) 216 51.4 5.3e-06
XP_016864751 (OMIM: 605656) PREDICTED: F-box/LRR-r ( 486) 216 51.4 5.7e-06
NP_036436 (OMIM: 605656) F-box/LRR-repeat protein ( 491) 216 51.5 5.8e-06
XP_016866217 (OMIM: 605654,615471) PREDICTED: F-bo ( 379) 203 48.9 2.6e-05
XP_005270207 (OMIM: 610287) PREDICTED: F-box/LRR-r ( 300) 200 48.3 3.1e-05
NP_077302 (OMIM: 610287) F-box/LRR-repeat protein ( 300) 200 48.3 3.1e-05
XP_016872120 (OMIM: 610287) PREDICTED: F-box/LRR-r ( 300) 200 48.3 3.1e-05
XP_005270208 (OMIM: 610287) PREDICTED: F-box/LRR-r ( 300) 200 48.3 3.1e-05
NP_001265645 (OMIM: 605654,615471) F-box/LRR-repea ( 621) 203 49.0 3.9e-05
XP_016866215 (OMIM: 605654,615471) PREDICTED: F-bo ( 621) 203 49.0 3.9e-05
NP_036292 (OMIM: 605654,615471) F-box/LRR-repeat p ( 621) 203 49.0 3.9e-05
XP_005270206 (OMIM: 610287) PREDICTED: F-box/LRR-r ( 387) 200 48.4 3.9e-05
NP_036294 (OMIM: 609076) F-box/LRR-repeat protein ( 539) 181 44.8 0.00062
XP_016861583 (OMIM: 605652) PREDICTED: F-box/LRR-r ( 318) 167 42.1 0.0025
XP_005265074 (OMIM: 605652) PREDICTED: F-box/LRR-r ( 318) 167 42.1 0.0025
XP_016861581 (OMIM: 605652) PREDICTED: F-box/LRR-r ( 349) 167 42.1 0.0027
XP_011531861 (OMIM: 605652) PREDICTED: F-box/LRR-r ( 349) 167 42.1 0.0027
XP_005265072 (OMIM: 605652) PREDICTED: F-box/LRR-r ( 349) 167 42.1 0.0027
XP_016861582 (OMIM: 605652) PREDICTED: F-box/LRR-r ( 349) 167 42.1 0.0027
XP_005265073 (OMIM: 605652) PREDICTED: F-box/LRR-r ( 349) 167 42.1 0.0027
NP_060173 (OMIM: 609079) F-box/LRR-repeat protein ( 326) 163 41.3 0.0043
>>NP_005974 (OMIM: 601436) S-phase kinase-associated pro (424 aa)
initn: 2848 init1: 2848 opt: 2848 Z-score: 2925.3 bits: 550.3 E(85289): 3.4e-156
Smith-Waterman score: 2848; 100.0% identity (100.0% similar) in 424 aa overlap (1-424:1-424)
10 20 30 40 50 60
pF1KB4 MHRKHLQEIPDLSSNVATSFTWGWDSSKTSELLSGMGVSALEKEEPDSENIPQELLSNLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MHRKHLQEIPDLSSNVATSFTWGWDSSKTSELLSGMGVSALEKEEPDSENIPQELLSNLG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 HPESPPRKRLKSKGSDKDFVIVRRPKLNRENFPGVSWDSLPDELLLGIFSCLCLPELLKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 HPESPPRKRLKSKGSDKDFVIVRRPKLNRENFPGVSWDSLPDELLLGIFSCLCLPELLKV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 SGVCKRWYRLASDESLWQTLDLTGKNLHPDVTGRLLSQGVIAFRCPRSFMDQPLAEHFSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SGVCKRWYRLASDESLWQTLDLTGKNLHPDVTGRLLSQGVIAFRCPRSFMDQPLAEHFSP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 FRVQHMDLSNSVIEVSTLHGILSQCSKLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 FRVQHMDLSNSVIEVSTLHGILSQCSKLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 SGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 DLSTLVRRCPNLVHLDLSDSVMLKNDCFQEFFQLNYLQHLSLSRCYDIIPETLLELGEIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 DLSTLVRRCPNLVHLDLSDSVMLKNDCFQEFFQLNYLQHLSLSRCYDIIPETLLELGEIP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 TLKTLQVFGIVPDGTLQLLKEALPHLQINCSHFTTIARPTIGNKKNQEIWGIKCRLTLQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 TLKTLQVFGIVPDGTLQLLKEALPHLQINCSHFTTIARPTIGNKKNQEIWGIKCRLTLQK
370 380 390 400 410 420
pF1KB4 PSCL
::::
NP_005 PSCL
>>XP_011512384 (OMIM: 601436) PREDICTED: S-phase kinase- (358 aa)
initn: 2375 init1: 2375 opt: 2375 Z-score: 2441.8 bits: 460.6 E(85289): 2.8e-129
Smith-Waterman score: 2375; 100.0% identity (100.0% similar) in 354 aa overlap (1-354:1-354)
10 20 30 40 50 60
pF1KB4 MHRKHLQEIPDLSSNVATSFTWGWDSSKTSELLSGMGVSALEKEEPDSENIPQELLSNLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MHRKHLQEIPDLSSNVATSFTWGWDSSKTSELLSGMGVSALEKEEPDSENIPQELLSNLG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 HPESPPRKRLKSKGSDKDFVIVRRPKLNRENFPGVSWDSLPDELLLGIFSCLCLPELLKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HPESPPRKRLKSKGSDKDFVIVRRPKLNRENFPGVSWDSLPDELLLGIFSCLCLPELLKV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 SGVCKRWYRLASDESLWQTLDLTGKNLHPDVTGRLLSQGVIAFRCPRSFMDQPLAEHFSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGVCKRWYRLASDESLWQTLDLTGKNLHPDVTGRLLSQGVIAFRCPRSFMDQPLAEHFSP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 FRVQHMDLSNSVIEVSTLHGILSQCSKLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FRVQHMDLSNSVIEVSTLHGILSQCSKLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 SGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 DLSTLVRRCPNLVHLDLSDSVMLKNDCFQEFFQLNYLQHLSLSRCYDIIPETLLELGEIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLSTLVRRCPNLVHLDLSDSVMLKNDCFQEFFQLNYLQHLSLSRCYDIIPETLLIQNS
310 320 330 340 350
370 380 390 400 410 420
pF1KB4 TLKTLQVFGIVPDGTLQLLKEALPHLQINCSHFTTIARPTIGNKKNQEIWGIKCRLTLQK
>>XP_011512383 (OMIM: 601436) PREDICTED: S-phase kinase- (379 aa)
initn: 2375 init1: 2375 opt: 2375 Z-score: 2441.5 bits: 460.6 E(85289): 3e-129
Smith-Waterman score: 2375; 100.0% identity (100.0% similar) in 354 aa overlap (1-354:1-354)
10 20 30 40 50 60
pF1KB4 MHRKHLQEIPDLSSNVATSFTWGWDSSKTSELLSGMGVSALEKEEPDSENIPQELLSNLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MHRKHLQEIPDLSSNVATSFTWGWDSSKTSELLSGMGVSALEKEEPDSENIPQELLSNLG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 HPESPPRKRLKSKGSDKDFVIVRRPKLNRENFPGVSWDSLPDELLLGIFSCLCLPELLKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HPESPPRKRLKSKGSDKDFVIVRRPKLNRENFPGVSWDSLPDELLLGIFSCLCLPELLKV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 SGVCKRWYRLASDESLWQTLDLTGKNLHPDVTGRLLSQGVIAFRCPRSFMDQPLAEHFSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGVCKRWYRLASDESLWQTLDLTGKNLHPDVTGRLLSQGVIAFRCPRSFMDQPLAEHFSP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 FRVQHMDLSNSVIEVSTLHGILSQCSKLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FRVQHMDLSNSVIEVSTLHGILSQCSKLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 SGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 DLSTLVRRCPNLVHLDLSDSVMLKNDCFQEFFQLNYLQHLSLSRCYDIIPETLLELGEIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLSTLVRRCPNLVHLDLSDSVMLKNDCFQEFFQLNYLQHLSLSRCYDIIPETLLGHECKC
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 TLKTLQVFGIVPDGTLQLLKEALPHLQINCSHFTTIARPTIGNKKNQEIWGIKCRLTLQK
XP_011 TRSIKNIKSKLSEEPTLTR
370
>>NP_116026 (OMIM: 601436) S-phase kinase-associated pro (410 aa)
initn: 2375 init1: 2375 opt: 2375 Z-score: 2440.9 bits: 460.6 E(85289): 3.2e-129
Smith-Waterman score: 2375; 100.0% identity (100.0% similar) in 354 aa overlap (1-354:1-354)
10 20 30 40 50 60
pF1KB4 MHRKHLQEIPDLSSNVATSFTWGWDSSKTSELLSGMGVSALEKEEPDSENIPQELLSNLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 MHRKHLQEIPDLSSNVATSFTWGWDSSKTSELLSGMGVSALEKEEPDSENIPQELLSNLG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 HPESPPRKRLKSKGSDKDFVIVRRPKLNRENFPGVSWDSLPDELLLGIFSCLCLPELLKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 HPESPPRKRLKSKGSDKDFVIVRRPKLNRENFPGVSWDSLPDELLLGIFSCLCLPELLKV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 SGVCKRWYRLASDESLWQTLDLTGKNLHPDVTGRLLSQGVIAFRCPRSFMDQPLAEHFSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 SGVCKRWYRLASDESLWQTLDLTGKNLHPDVTGRLLSQGVIAFRCPRSFMDQPLAEHFSP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 FRVQHMDLSNSVIEVSTLHGILSQCSKLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 FRVQHMDLSNSVIEVSTLHGILSQCSKLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 SGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 SGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 DLSTLVRRCPNLVHLDLSDSVMLKNDCFQEFFQLNYLQHLSLSRCYDIIPETLLELGEIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 DLSTLVRRCPNLVHLDLSDSVMLKNDCFQEFFQLNYLQHLSLSRCYDIIPETLLLVTRAG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 TLKTLQVFGIVPDGTLQLLKEALPHLQINCSHFTTIARPTIGNKKNQEIWGIKCRLTLQK
NP_116 VRIRLDSDIGCPQTYRTSKLKSSHKLFCQHVRVICIFVCDFYFYRLVLKQ
370 380 390 400 410
>>XP_011512385 (OMIM: 601436) PREDICTED: S-phase kinase- (255 aa)
initn: 1688 init1: 1688 opt: 1688 Z-score: 1740.3 bits: 330.3 E(85289): 3.4e-90
Smith-Waterman score: 1688; 100.0% identity (100.0% similar) in 255 aa overlap (170-424:1-255)
140 150 160 170 180 190
pF1KB4 LDLTGKNLHPDVTGRLLSQGVIAFRCPRSFMDQPLAEHFSPFRVQHMDLSNSVIEVSTLH
::::::::::::::::::::::::::::::
XP_011 MDQPLAEHFSPFRVQHMDLSNSVIEVSTLH
10 20 30
200 210 220 230 240 250
pF1KB4 GILSQCSKLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGCSGFSEFALQTLLSSCSRLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GILSQCSKLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGCSGFSEFALQTLLSSCSRLD
40 50 60 70 80 90
260 270 280 290 300 310
pF1KB4 ELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKSDLSTLVRRCPNLVHLDLSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKSDLSTLVRRCPNLVHLDLSD
100 110 120 130 140 150
320 330 340 350 360 370
pF1KB4 SVMLKNDCFQEFFQLNYLQHLSLSRCYDIIPETLLELGEIPTLKTLQVFGIVPDGTLQLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVMLKNDCFQEFFQLNYLQHLSLSRCYDIIPETLLELGEIPTLKTLQVFGIVPDGTLQLL
160 170 180 190 200 210
380 390 400 410 420
pF1KB4 KEALPHLQINCSHFTTIARPTIGNKKNQEIWGIKCRLTLQKPSCL
:::::::::::::::::::::::::::::::::::::::::::::
XP_011 KEALPHLQINCSHFTTIARPTIGNKKNQEIWGIKCRLTLQKPSCL
220 230 240 250
>>NP_001230049 (OMIM: 601436) S-phase kinase-associated (210 aa)
initn: 1329 init1: 1329 opt: 1329 Z-score: 1373.8 bits: 262.2 E(85289): 8.8e-70
Smith-Waterman score: 1329; 99.5% identity (100.0% similar) in 201 aa overlap (224-424:10-210)
200 210 220 230 240 250
pF1KB4 EVSTLHGILSQCSKLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGCSGFSEFALQTLLS
.:::::::::::::::::::::::::::::
NP_001 MDQPLAEHFSTLAKNSNLVRLNLSGCSGFSEFALQTLLS
10 20 30
260 270 280 290 300 310
pF1KB4 SCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKSDLSTLVRRCPNLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKSDLSTLVRRCPNLV
40 50 60 70 80 90
320 330 340 350 360 370
pF1KB4 HLDLSDSVMLKNDCFQEFFQLNYLQHLSLSRCYDIIPETLLELGEIPTLKTLQVFGIVPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HLDLSDSVMLKNDCFQEFFQLNYLQHLSLSRCYDIIPETLLELGEIPTLKTLQVFGIVPD
100 110 120 130 140 150
380 390 400 410 420
pF1KB4 GTLQLLKEALPHLQINCSHFTTIARPTIGNKKNQEIWGIKCRLTLQKPSCL
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GTLQLLKEALPHLQINCSHFTTIARPTIGNKKNQEIWGIKCRLTLQKPSCL
160 170 180 190 200 210
>>XP_016865242 (OMIM: 601436) PREDICTED: S-phase kinase- (241 aa)
initn: 1215 init1: 1215 opt: 1215 Z-score: 1256.1 bits: 240.6 E(85289): 3.2e-63
Smith-Waterman score: 1215; 100.0% identity (100.0% similar) in 185 aa overlap (170-354:1-185)
140 150 160 170 180 190
pF1KB4 LDLTGKNLHPDVTGRLLSQGVIAFRCPRSFMDQPLAEHFSPFRVQHMDLSNSVIEVSTLH
::::::::::::::::::::::::::::::
XP_016 MDQPLAEHFSPFRVQHMDLSNSVIEVSTLH
10 20 30
200 210 220 230 240 250
pF1KB4 GILSQCSKLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGCSGFSEFALQTLLSSCSRLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GILSQCSKLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGCSGFSEFALQTLLSSCSRLD
40 50 60 70 80 90
260 270 280 290 300 310
pF1KB4 ELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKSDLSTLVRRCPNLVHLDLSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKSDLSTLVRRCPNLVHLDLSD
100 110 120 130 140 150
320 330 340 350 360 370
pF1KB4 SVMLKNDCFQEFFQLNYLQHLSLSRCYDIIPETLLELGEIPTLKTLQVFGIVPDGTLQLL
:::::::::::::::::::::::::::::::::::
XP_016 SVMLKNDCFQEFFQLNYLQHLSLSRCYDIIPETLLLVTRAGVRIRLDSDIGCPQTYRTSK
160 170 180 190 200 210
380 390 400 410 420
pF1KB4 KEALPHLQINCSHFTTIARPTIGNKKNQEIWGIKCRLTLQKPSCL
XP_016 LKSSHKLFCQHVRVICIFVCDFYFYRLVLKQ
220 230 240
>>NP_001165184 (OMIM: 605652) F-box/LRR-repeat protein 2 (355 aa)
initn: 362 init1: 116 opt: 293 Z-score: 309.1 bits: 66.0 E(85289): 1.8e-10
Smith-Waterman score: 296; 26.6% identity (55.5% similar) in 346 aa overlap (91-421:6-324)
70 80 90 100 110 120
pF1KB4 HPESPPRKRLKSKGSDKDFVIVRRPKLNRENFPGVSWDSLPDELLLGIFSCLCLPELLKV
: :. .:: :::: ::: : . : .
NP_001 MVFSNNDEGLINKKLPKELLLRIFSFLDIVTLCRC
10 20 30
130 140 150 160 170 180
pF1KB4 SGVCKRWYRLASDESLWQTLDLTGKNLHPDVTGRLLSQGVIAFRCPRSFMDQPLAEHFSP
. . : : :: : : :: .:: :.. :: ::.. . :. :: .:.
NP_001 AQISKAWNILALDGSNWQRIDLF--NFQTDVEGRVVEN--ISKRCG-GFL----------
40 50 60 70 80
190 200 210 220
pF1KB4 FRVQHMDLSNSV-IEVSTLHGILSQCSKLQNLSLEG-LRLSDPIVNTLAK----------
....: . . . :.:. . ..: ....:.:.: ...: .:..
NP_001 ---RKLSLRGCIGVGDSSLKTFAQNCRNIEHLNLNGCTKITDSTCYSLSRFCSKLKHIQN
90 100 110 120 130
230 240 250 260 270 280
pF1KB4 -NSNLVRLNLSGCSGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQ
.:: :::..:: ... .. . .: ::. : :: : ..:. ..... .. :
NP_001 YCHELVSLNLQSCSRITDEGVVQICRGCHRLQALCLSGCSNLTD--ASLTALGLNCPRLQ
140 150 160 170 180 190
290 300 310 320 330 340
pF1KB4 LNLSGYRKNLQKSDLSTLVRRCPNLVHLDLSDSVMLKNDCF-QEFFQLNYLQHLSLSRCY
. .. ..: . .. :.: : .: ..:: . ... .. . : .. :: ::::.:
NP_001 ILEAARCSHLTDAGFTLLARNCHELEKMDLEECILITDSTLIQLSIHCPKLQALSLSHCE
200 210 220 230 240 250
350 360 370 380 390 400
pF1KB4 DIIPETLLELGEIPT-LKTLQVFGIVPDGTLQLLKEALPHLQINCSHFTTIARPTIGNKK
: . .:.:.. . :.:. . :. : . :: ::. :: . : . . .
NP_001 LITDDGILHLSNSTCGHERLRVLEL--DNCLLITDVALEHLE-NCR---GLERLELYDCQ
260 270 280 290 300
410 420
pF1KB4 NQEIWGIKCRLTLQKPSCL
. ::: :. : :
NP_001 QVTRAGIK-RMRAQLPHVKVHAYFAPVTPPTAVAGSGQRLCRCCVIL
310 320 330 340 350
>>NP_001171835 (OMIM: 609086) F-box/LRR-repeat protein 2 (404 aa)
initn: 290 init1: 114 opt: 264 Z-score: 278.5 bits: 60.5 E(85289): 8.9e-09
Smith-Waterman score: 264; 28.1% identity (57.1% similar) in 310 aa overlap (100-388:28-324)
70 80 90 100 110 120
pF1KB4 LKSKGSDKDFVIVRRPKLNRENFPGVSWDSLPDELLLGIFSCLCLPELLKVSGVCKRWYR
:: :::: ::: : . : . . : . :
NP_001 MRRDVNGVTKSRFEMFSNSDEAVINKKLPKELLLRIFSFLDVVTLCRCAQVSRAWNV
10 20 30 40 50
130 140 150 160 170 180
pF1KB4 LASDESLWQTLDLTGKNLHPDVTGRLLSQGVIAFRCPRSFMDQP-----LAEHFSPFRVQ
:: : : :: .:: ... :. ::.. . :. :: .:. . :. . .:.
NP_001 LALDGSNWQRIDLF--DFQRDIEGRVVEN--ISKRCG-GFLRKLSLRGCLGVGDNALRTF
60 70 80 90 100 110
190 200 210 220 230
pF1KB4 HMDLSNSVIEVSTLHGILSQCSKLQNLS----LEGLRLS--DPI----VNTLAKN-SNLV
.. : ::: .:.: :.: . :: : .: : . ...:... ..:
NP_001 AQNCRN--IEVLNLNG----CTKTTDAEGCPLLEQLNISWCDQVTKDGIQALVRGCGGLK
120 130 140 150 160
240 250 260 270 280 290
pF1KB4 RLNLSGCSGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGY
: :.::. . . ::. . . : .: :::. :...:.. . ... . . . .: ::
NP_001 ALFLKGCTQLEDEALKYIGAHCPELVTLNLQTCLQITDEGL-ITICRGCHKLQSLCASGC
170 180 190 200 210 220
300 310 320 330 340 350
pF1KB4 RKNLQKSDLSTLVRRCPNLVHLDLSDSVMLKNDCFQEFFQ-LNYLQHLSLSRCYDIIPET
.:. . :..: . :: : :... .: . : . . . :....: .: .: :
NP_001 -SNITDAILNALGQNCPRLRILEVARCSQLTDVGFTTLARNCHELEKMDLEECVQITDST
230 240 250 260 270 280
360 370 380 390 400
pF1KB4 LLELG-EIPTLKTLQVFG---IVPDGTLQLLKEALPHLQINCSHFTTIARPTIGNKKNQE
:..:. . : :..:.. :. :: .: . : : :.
NP_001 LIQLSIHCPRLQVLSLSHCELITDDGIRHLGNGACAHDQLEVIELDNCPLITDASLEHLK
290 300 310 320 330 340
410 420
pF1KB4 IWGIKCRLTLQKPSCL
NP_001 SCHSLERIELYDCQQITRAGIKRLRTHLPNIKVHAYFAPVTPPPSVGGSRQRFCRCCIIL
350 360 370 380 390 400
>>XP_005257804 (OMIM: 609086) PREDICTED: F-box/LRR-repea (441 aa)
initn: 323 init1: 114 opt: 264 Z-score: 278.0 bits: 60.5 E(85289): 9.6e-09
Smith-Waterman score: 264; 28.1% identity (57.1% similar) in 310 aa overlap (100-388:65-361)
70 80 90 100 110 120
pF1KB4 LKSKGSDKDFVIVRRPKLNRENFPGVSWDSLPDELLLGIFSCLCLPELLKVSGVCKRWYR
:: :::: ::: : . : . . : . :
XP_005 KMAPSRDRLLHFGFKATMFSNSDEAVINKKLPKELLLRIFSFLDVVTLCRCAQVSRAWNV
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB4 LASDESLWQTLDLTGKNLHPDVTGRLLSQGVIAFRCPRSFMDQP-----LAEHFSPFRVQ
:: : : :: .:: ... :. ::.. . :. :: .:. . :. . .:.
XP_005 LALDGSNWQRIDLF--DFQRDIEGRVVEN--ISKRCG-GFLRKLSLRGCLGVGDNALRTF
100 110 120 130 140
190 200 210 220 230
pF1KB4 HMDLSNSVIEVSTLHGILSQCSKLQNLS----LEGLRLS--DPI----VNTLAKN-SNLV
.. : ::: .:.: :.: . :: : .: : . ...:... ..:
XP_005 AQNCRN--IEVLNLNG----CTKTTDAEGCPLLEQLNISWCDQVTKDGIQALVRGCGGLK
150 160 170 180 190 200
240 250 260 270 280 290
pF1KB4 RLNLSGCSGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGY
: :.::. . . ::. . . : .: :::. :...:.. . ... . . . .: ::
XP_005 ALFLKGCTQLEDEALKYIGAHCPELVTLNLQTCLQITDEGL-ITICRGCHKLQSLCASGC
210 220 230 240 250 260
300 310 320 330 340 350
pF1KB4 RKNLQKSDLSTLVRRCPNLVHLDLSDSVMLKNDCFQEFFQ-LNYLQHLSLSRCYDIIPET
.:. . :..: . :: : :... .: . : . . . :....: .: .: :
XP_005 -SNITDAILNALGQNCPRLRILEVARCSQLTDVGFTTLARNCHELEKMDLEECVQITDST
270 280 290 300 310 320
360 370 380 390 400
pF1KB4 LLELG-EIPTLKTLQVFG---IVPDGTLQLLKEALPHLQINCSHFTTIARPTIGNKKNQE
:..:. . : :..:.. :. :: .: . : : :.
XP_005 LIQLSIHCPRLQVLSLSHCELITDDGIRHLGNGACAHDQLEVIELDNCPLITDASLEHLK
330 340 350 360 370 380
410 420
pF1KB4 IWGIKCRLTLQKPSCL
XP_005 SCHSLERIELYDCQQITRAGIKRLRTHLPNIKVHAYFAPVTPPPSVGGSRQRFCRCCIIL
390 400 410 420 430 440
424 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 21:23:27 2016 done: Thu Nov 3 21:23:28 2016
Total Scan time: 9.670 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]