Result of FASTA (omim) for pF1KB4066
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB4066, 424 aa
  1>>>pF1KB4066 424 - 424 aa - 424 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.3317+/-0.000375; mu= 12.3436+/- 0.023
 mean_var=95.2915+/-19.473, 0's: 0 Z-trim(114.7): 88  B-trim: 0 in 0/52
 Lambda= 0.131385
 statistics sampled from 24657 (24747) to 24657 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.671), E-opt: 0.2 (0.29), width:  16
 Scan time:  9.670

The best scores are:                                      opt bits E(85289)
NP_005974 (OMIM: 601436) S-phase kinase-associated ( 424) 2848 550.3 3.4e-156
XP_011512384 (OMIM: 601436) PREDICTED: S-phase kin ( 358) 2375 460.6 2.8e-129
XP_011512383 (OMIM: 601436) PREDICTED: S-phase kin ( 379) 2375 460.6  3e-129
NP_116026 (OMIM: 601436) S-phase kinase-associated ( 410) 2375 460.6 3.2e-129
XP_011512385 (OMIM: 601436) PREDICTED: S-phase kin ( 255) 1688 330.3 3.4e-90
NP_001230049 (OMIM: 601436) S-phase kinase-associa ( 210) 1329 262.2 8.8e-70
XP_016865242 (OMIM: 601436) PREDICTED: S-phase kin ( 241) 1215 240.6 3.2e-63
NP_001165184 (OMIM: 605652) F-box/LRR-repeat prote ( 355)  293 66.0 1.8e-10
NP_001171835 (OMIM: 609086) F-box/LRR-repeat prote ( 404)  264 60.5 8.9e-09
XP_005257804 (OMIM: 609086) PREDICTED: F-box/LRR-r ( 441)  264 60.5 9.6e-09
XP_011512300 (OMIM: 605656) PREDICTED: F-box/LRR-r ( 444)  216 51.4 5.3e-06
NP_001265246 (OMIM: 605656) F-box/LRR-repeat prote ( 444)  216 51.4 5.3e-06
XP_016864751 (OMIM: 605656) PREDICTED: F-box/LRR-r ( 486)  216 51.4 5.7e-06
NP_036436 (OMIM: 605656) F-box/LRR-repeat protein  ( 491)  216 51.5 5.8e-06
XP_016866217 (OMIM: 605654,615471) PREDICTED: F-bo ( 379)  203 48.9 2.6e-05
XP_005270207 (OMIM: 610287) PREDICTED: F-box/LRR-r ( 300)  200 48.3 3.1e-05
NP_077302 (OMIM: 610287) F-box/LRR-repeat protein  ( 300)  200 48.3 3.1e-05
XP_016872120 (OMIM: 610287) PREDICTED: F-box/LRR-r ( 300)  200 48.3 3.1e-05
XP_005270208 (OMIM: 610287) PREDICTED: F-box/LRR-r ( 300)  200 48.3 3.1e-05
NP_001265645 (OMIM: 605654,615471) F-box/LRR-repea ( 621)  203 49.0 3.9e-05
XP_016866215 (OMIM: 605654,615471) PREDICTED: F-bo ( 621)  203 49.0 3.9e-05
NP_036292 (OMIM: 605654,615471) F-box/LRR-repeat p ( 621)  203 49.0 3.9e-05
XP_005270206 (OMIM: 610287) PREDICTED: F-box/LRR-r ( 387)  200 48.4 3.9e-05
NP_036294 (OMIM: 609076) F-box/LRR-repeat protein  ( 539)  181 44.8 0.00062
XP_016861583 (OMIM: 605652) PREDICTED: F-box/LRR-r ( 318)  167 42.1  0.0025
XP_005265074 (OMIM: 605652) PREDICTED: F-box/LRR-r ( 318)  167 42.1  0.0025
XP_016861581 (OMIM: 605652) PREDICTED: F-box/LRR-r ( 349)  167 42.1  0.0027
XP_011531861 (OMIM: 605652) PREDICTED: F-box/LRR-r ( 349)  167 42.1  0.0027
XP_005265072 (OMIM: 605652) PREDICTED: F-box/LRR-r ( 349)  167 42.1  0.0027
XP_016861582 (OMIM: 605652) PREDICTED: F-box/LRR-r ( 349)  167 42.1  0.0027
XP_005265073 (OMIM: 605652) PREDICTED: F-box/LRR-r ( 349)  167 42.1  0.0027
NP_060173 (OMIM: 609079) F-box/LRR-repeat protein  ( 326)  163 41.3  0.0043


>>NP_005974 (OMIM: 601436) S-phase kinase-associated pro  (424 aa)
 initn: 2848 init1: 2848 opt: 2848  Z-score: 2925.3  bits: 550.3 E(85289): 3.4e-156
Smith-Waterman score: 2848; 100.0% identity (100.0% similar) in 424 aa overlap (1-424:1-424)

               10        20        30        40        50        60
pF1KB4 MHRKHLQEIPDLSSNVATSFTWGWDSSKTSELLSGMGVSALEKEEPDSENIPQELLSNLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MHRKHLQEIPDLSSNVATSFTWGWDSSKTSELLSGMGVSALEKEEPDSENIPQELLSNLG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB4 HPESPPRKRLKSKGSDKDFVIVRRPKLNRENFPGVSWDSLPDELLLGIFSCLCLPELLKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 HPESPPRKRLKSKGSDKDFVIVRRPKLNRENFPGVSWDSLPDELLLGIFSCLCLPELLKV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB4 SGVCKRWYRLASDESLWQTLDLTGKNLHPDVTGRLLSQGVIAFRCPRSFMDQPLAEHFSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SGVCKRWYRLASDESLWQTLDLTGKNLHPDVTGRLLSQGVIAFRCPRSFMDQPLAEHFSP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB4 FRVQHMDLSNSVIEVSTLHGILSQCSKLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 FRVQHMDLSNSVIEVSTLHGILSQCSKLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGC
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB4 SGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB4 DLSTLVRRCPNLVHLDLSDSVMLKNDCFQEFFQLNYLQHLSLSRCYDIIPETLLELGEIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 DLSTLVRRCPNLVHLDLSDSVMLKNDCFQEFFQLNYLQHLSLSRCYDIIPETLLELGEIP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB4 TLKTLQVFGIVPDGTLQLLKEALPHLQINCSHFTTIARPTIGNKKNQEIWGIKCRLTLQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 TLKTLQVFGIVPDGTLQLLKEALPHLQINCSHFTTIARPTIGNKKNQEIWGIKCRLTLQK
              370       380       390       400       410       420

           
pF1KB4 PSCL
       ::::
NP_005 PSCL
           

>>XP_011512384 (OMIM: 601436) PREDICTED: S-phase kinase-  (358 aa)
 initn: 2375 init1: 2375 opt: 2375  Z-score: 2441.8  bits: 460.6 E(85289): 2.8e-129
Smith-Waterman score: 2375; 100.0% identity (100.0% similar) in 354 aa overlap (1-354:1-354)

               10        20        30        40        50        60
pF1KB4 MHRKHLQEIPDLSSNVATSFTWGWDSSKTSELLSGMGVSALEKEEPDSENIPQELLSNLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MHRKHLQEIPDLSSNVATSFTWGWDSSKTSELLSGMGVSALEKEEPDSENIPQELLSNLG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB4 HPESPPRKRLKSKGSDKDFVIVRRPKLNRENFPGVSWDSLPDELLLGIFSCLCLPELLKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HPESPPRKRLKSKGSDKDFVIVRRPKLNRENFPGVSWDSLPDELLLGIFSCLCLPELLKV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB4 SGVCKRWYRLASDESLWQTLDLTGKNLHPDVTGRLLSQGVIAFRCPRSFMDQPLAEHFSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGVCKRWYRLASDESLWQTLDLTGKNLHPDVTGRLLSQGVIAFRCPRSFMDQPLAEHFSP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB4 FRVQHMDLSNSVIEVSTLHGILSQCSKLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FRVQHMDLSNSVIEVSTLHGILSQCSKLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGC
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB4 SGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB4 DLSTLVRRCPNLVHLDLSDSVMLKNDCFQEFFQLNYLQHLSLSRCYDIIPETLLELGEIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::      
XP_011 DLSTLVRRCPNLVHLDLSDSVMLKNDCFQEFFQLNYLQHLSLSRCYDIIPETLLIQNS  
              310       320       330       340       350          

              370       380       390       400       410       420
pF1KB4 TLKTLQVFGIVPDGTLQLLKEALPHLQINCSHFTTIARPTIGNKKNQEIWGIKCRLTLQK

>>XP_011512383 (OMIM: 601436) PREDICTED: S-phase kinase-  (379 aa)
 initn: 2375 init1: 2375 opt: 2375  Z-score: 2441.5  bits: 460.6 E(85289): 3e-129
Smith-Waterman score: 2375; 100.0% identity (100.0% similar) in 354 aa overlap (1-354:1-354)

               10        20        30        40        50        60
pF1KB4 MHRKHLQEIPDLSSNVATSFTWGWDSSKTSELLSGMGVSALEKEEPDSENIPQELLSNLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MHRKHLQEIPDLSSNVATSFTWGWDSSKTSELLSGMGVSALEKEEPDSENIPQELLSNLG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB4 HPESPPRKRLKSKGSDKDFVIVRRPKLNRENFPGVSWDSLPDELLLGIFSCLCLPELLKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HPESPPRKRLKSKGSDKDFVIVRRPKLNRENFPGVSWDSLPDELLLGIFSCLCLPELLKV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB4 SGVCKRWYRLASDESLWQTLDLTGKNLHPDVTGRLLSQGVIAFRCPRSFMDQPLAEHFSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGVCKRWYRLASDESLWQTLDLTGKNLHPDVTGRLLSQGVIAFRCPRSFMDQPLAEHFSP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB4 FRVQHMDLSNSVIEVSTLHGILSQCSKLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FRVQHMDLSNSVIEVSTLHGILSQCSKLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGC
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB4 SGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB4 DLSTLVRRCPNLVHLDLSDSVMLKNDCFQEFFQLNYLQHLSLSRCYDIIPETLLELGEIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::      
XP_011 DLSTLVRRCPNLVHLDLSDSVMLKNDCFQEFFQLNYLQHLSLSRCYDIIPETLLGHECKC
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB4 TLKTLQVFGIVPDGTLQLLKEALPHLQINCSHFTTIARPTIGNKKNQEIWGIKCRLTLQK
                                                                   
XP_011 TRSIKNIKSKLSEEPTLTR                                         
              370                                                  

>>NP_116026 (OMIM: 601436) S-phase kinase-associated pro  (410 aa)
 initn: 2375 init1: 2375 opt: 2375  Z-score: 2440.9  bits: 460.6 E(85289): 3.2e-129
Smith-Waterman score: 2375; 100.0% identity (100.0% similar) in 354 aa overlap (1-354:1-354)

               10        20        30        40        50        60
pF1KB4 MHRKHLQEIPDLSSNVATSFTWGWDSSKTSELLSGMGVSALEKEEPDSENIPQELLSNLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 MHRKHLQEIPDLSSNVATSFTWGWDSSKTSELLSGMGVSALEKEEPDSENIPQELLSNLG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB4 HPESPPRKRLKSKGSDKDFVIVRRPKLNRENFPGVSWDSLPDELLLGIFSCLCLPELLKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 HPESPPRKRLKSKGSDKDFVIVRRPKLNRENFPGVSWDSLPDELLLGIFSCLCLPELLKV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB4 SGVCKRWYRLASDESLWQTLDLTGKNLHPDVTGRLLSQGVIAFRCPRSFMDQPLAEHFSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 SGVCKRWYRLASDESLWQTLDLTGKNLHPDVTGRLLSQGVIAFRCPRSFMDQPLAEHFSP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB4 FRVQHMDLSNSVIEVSTLHGILSQCSKLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 FRVQHMDLSNSVIEVSTLHGILSQCSKLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGC
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB4 SGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 SGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKS
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB4 DLSTLVRRCPNLVHLDLSDSVMLKNDCFQEFFQLNYLQHLSLSRCYDIIPETLLELGEIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::      
NP_116 DLSTLVRRCPNLVHLDLSDSVMLKNDCFQEFFQLNYLQHLSLSRCYDIIPETLLLVTRAG
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB4 TLKTLQVFGIVPDGTLQLLKEALPHLQINCSHFTTIARPTIGNKKNQEIWGIKCRLTLQK
                                                                   
NP_116 VRIRLDSDIGCPQTYRTSKLKSSHKLFCQHVRVICIFVCDFYFYRLVLKQ          
              370       380       390       400       410          

>>XP_011512385 (OMIM: 601436) PREDICTED: S-phase kinase-  (255 aa)
 initn: 1688 init1: 1688 opt: 1688  Z-score: 1740.3  bits: 330.3 E(85289): 3.4e-90
Smith-Waterman score: 1688; 100.0% identity (100.0% similar) in 255 aa overlap (170-424:1-255)

     140       150       160       170       180       190         
pF1KB4 LDLTGKNLHPDVTGRLLSQGVIAFRCPRSFMDQPLAEHFSPFRVQHMDLSNSVIEVSTLH
                                     ::::::::::::::::::::::::::::::
XP_011                               MDQPLAEHFSPFRVQHMDLSNSVIEVSTLH
                                             10        20        30

     200       210       220       230       240       250         
pF1KB4 GILSQCSKLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGCSGFSEFALQTLLSSCSRLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GILSQCSKLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGCSGFSEFALQTLLSSCSRLD
               40        50        60        70        80        90

     260       270       280       290       300       310         
pF1KB4 ELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKSDLSTLVRRCPNLVHLDLSD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKSDLSTLVRRCPNLVHLDLSD
              100       110       120       130       140       150

     320       330       340       350       360       370         
pF1KB4 SVMLKNDCFQEFFQLNYLQHLSLSRCYDIIPETLLELGEIPTLKTLQVFGIVPDGTLQLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVMLKNDCFQEFFQLNYLQHLSLSRCYDIIPETLLELGEIPTLKTLQVFGIVPDGTLQLL
              160       170       180       190       200       210

     380       390       400       410       420    
pF1KB4 KEALPHLQINCSHFTTIARPTIGNKKNQEIWGIKCRLTLQKPSCL
       :::::::::::::::::::::::::::::::::::::::::::::
XP_011 KEALPHLQINCSHFTTIARPTIGNKKNQEIWGIKCRLTLQKPSCL
              220       230       240       250     

>>NP_001230049 (OMIM: 601436) S-phase kinase-associated   (210 aa)
 initn: 1329 init1: 1329 opt: 1329  Z-score: 1373.8  bits: 262.2 E(85289): 8.8e-70
Smith-Waterman score: 1329; 99.5% identity (100.0% similar) in 201 aa overlap (224-424:10-210)

           200       210       220       230       240       250   
pF1KB4 EVSTLHGILSQCSKLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGCSGFSEFALQTLLS
                                     .:::::::::::::::::::::::::::::
NP_001                      MDQPLAEHFSTLAKNSNLVRLNLSGCSGFSEFALQTLLS
                                    10        20        30         

           260       270       280       290       300       310   
pF1KB4 SCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKSDLSTLVRRCPNLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKSDLSTLVRRCPNLV
      40        50        60        70        80        90         

           320       330       340       350       360       370   
pF1KB4 HLDLSDSVMLKNDCFQEFFQLNYLQHLSLSRCYDIIPETLLELGEIPTLKTLQVFGIVPD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HLDLSDSVMLKNDCFQEFFQLNYLQHLSLSRCYDIIPETLLELGEIPTLKTLQVFGIVPD
     100       110       120       130       140       150         

           380       390       400       410       420    
pF1KB4 GTLQLLKEALPHLQINCSHFTTIARPTIGNKKNQEIWGIKCRLTLQKPSCL
       :::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GTLQLLKEALPHLQINCSHFTTIARPTIGNKKNQEIWGIKCRLTLQKPSCL
     160       170       180       190       200       210

>>XP_016865242 (OMIM: 601436) PREDICTED: S-phase kinase-  (241 aa)
 initn: 1215 init1: 1215 opt: 1215  Z-score: 1256.1  bits: 240.6 E(85289): 3.2e-63
Smith-Waterman score: 1215; 100.0% identity (100.0% similar) in 185 aa overlap (170-354:1-185)

     140       150       160       170       180       190         
pF1KB4 LDLTGKNLHPDVTGRLLSQGVIAFRCPRSFMDQPLAEHFSPFRVQHMDLSNSVIEVSTLH
                                     ::::::::::::::::::::::::::::::
XP_016                               MDQPLAEHFSPFRVQHMDLSNSVIEVSTLH
                                             10        20        30

     200       210       220       230       240       250         
pF1KB4 GILSQCSKLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGCSGFSEFALQTLLSSCSRLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GILSQCSKLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGCSGFSEFALQTLLSSCSRLD
               40        50        60        70        80        90

     260       270       280       290       300       310         
pF1KB4 ELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKSDLSTLVRRCPNLVHLDLSD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKSDLSTLVRRCPNLVHLDLSD
              100       110       120       130       140       150

     320       330       340       350       360       370         
pF1KB4 SVMLKNDCFQEFFQLNYLQHLSLSRCYDIIPETLLELGEIPTLKTLQVFGIVPDGTLQLL
       :::::::::::::::::::::::::::::::::::                         
XP_016 SVMLKNDCFQEFFQLNYLQHLSLSRCYDIIPETLLLVTRAGVRIRLDSDIGCPQTYRTSK
              160       170       180       190       200       210

     380       390       400       410       420    
pF1KB4 KEALPHLQINCSHFTTIARPTIGNKKNQEIWGIKCRLTLQKPSCL
                                                    
XP_016 LKSSHKLFCQHVRVICIFVCDFYFYRLVLKQ              
              220       230       240               

>>NP_001165184 (OMIM: 605652) F-box/LRR-repeat protein 2  (355 aa)
 initn: 362 init1: 116 opt: 293  Z-score: 309.1  bits: 66.0 E(85289): 1.8e-10
Smith-Waterman score: 296; 26.6% identity (55.5% similar) in 346 aa overlap (91-421:6-324)

               70        80        90       100       110       120
pF1KB4 HPESPPRKRLKSKGSDKDFVIVRRPKLNRENFPGVSWDSLPDELLLGIFSCLCLPELLKV
                                     :  :.   .:: :::: ::: : .  : . 
NP_001                          MVFSNNDEGLINKKLPKELLLRIFSFLDIVTLCRC
                                        10        20        30     

              130       140       150       160       170       180
pF1KB4 SGVCKRWYRLASDESLWQTLDLTGKNLHPDVTGRLLSQGVIAFRCPRSFMDQPLAEHFSP
       . . : :  :: : : :: .::   :.. :: ::.. .  :. ::  .:.          
NP_001 AQISKAWNILALDGSNWQRIDLF--NFQTDVEGRVVEN--ISKRCG-GFL----------
          40        50          60        70           80          

              190        200       210        220                  
pF1KB4 FRVQHMDLSNSV-IEVSTLHGILSQCSKLQNLSLEG-LRLSDPIVNTLAK----------
          ....: . . .  :.:. . ..: ....:.:.:  ...:    .:..          
NP_001 ---RKLSLRGCIGVGDSSLKTFAQNCRNIEHLNLNGCTKITDSTCYSLSRFCSKLKHIQN
                  90       100       110       120       130       

       230       240       250       260       270       280       
pF1KB4 -NSNLVRLNLSGCSGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQ
          .:: :::..:: ... ..  .  .: ::. : :: : ..:.  .....  ..    :
NP_001 YCHELVSLNLQSCSRITDEGVVQICRGCHRLQALCLSGCSNLTD--ASLTALGLNCPRLQ
       140       150       160       170       180         190     

       290       300       310       320        330       340      
pF1KB4 LNLSGYRKNLQKSDLSTLVRRCPNLVHLDLSDSVMLKNDCF-QEFFQLNYLQHLSLSRCY
       .  ..  ..:  . .. :.: : .: ..:: . ... .. . :  ..   :: ::::.: 
NP_001 ILEAARCSHLTDAGFTLLARNCHELEKMDLEECILITDSTLIQLSIHCPKLQALSLSHCE
         200       210       220       230       240       250     

        350       360        370       380       390       400     
pF1KB4 DIIPETLLELGEIPT-LKTLQVFGIVPDGTLQLLKEALPHLQINCSHFTTIARPTIGNKK
        :  . .:.:..     . :.:. .  :. : .   :: ::. ::     . :  . . .
NP_001 LITDDGILHLSNSTCGHERLRVLEL--DNCLLITDVALEHLE-NCR---GLERLELYDCQ
         260       270       280         290           300         

         410       420                                
pF1KB4 NQEIWGIKCRLTLQKPSCL                            
       .    ::: :.  : :                               
NP_001 QVTRAGIK-RMRAQLPHVKVHAYFAPVTPPTAVAGSGQRLCRCCVIL
     310        320       330       340       350     

>>NP_001171835 (OMIM: 609086) F-box/LRR-repeat protein 2  (404 aa)
 initn: 290 init1: 114 opt: 264  Z-score: 278.5  bits: 60.5 E(85289): 8.9e-09
Smith-Waterman score: 264; 28.1% identity (57.1% similar) in 310 aa overlap (100-388:28-324)

      70        80        90       100       110       120         
pF1KB4 LKSKGSDKDFVIVRRPKLNRENFPGVSWDSLPDELLLGIFSCLCLPELLKVSGVCKRWYR
                                     :: :::: ::: : .  : . . : . :  
NP_001    MRRDVNGVTKSRFEMFSNSDEAVINKKLPKELLLRIFSFLDVVTLCRCAQVSRAWNV
                  10        20        30        40        50       

     130       140       150       160       170            180    
pF1KB4 LASDESLWQTLDLTGKNLHPDVTGRLLSQGVIAFRCPRSFMDQP-----LAEHFSPFRVQ
       :: : : :: .::   ... :. ::.. .  :. ::  .:. .      :.   . .:. 
NP_001 LALDGSNWQRIDLF--DFQRDIEGRVVEN--ISKRCG-GFLRKLSLRGCLGVGDNALRTF
        60        70          80          90        100       110  

          190       200       210             220            230   
pF1KB4 HMDLSNSVIEVSTLHGILSQCSKLQNLS----LEGLRLS--DPI----VNTLAKN-SNLV
        ..  :  ::: .:.:    :.:  .      :: : .:  : .    ...:... ..: 
NP_001 AQNCRN--IEVLNLNG----CTKTTDAEGCPLLEQLNISWCDQVTKDGIQALVRGCGGLK
              120           130       140       150       160      

           240       250       260       270       280       290   
pF1KB4 RLNLSGCSGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGY
        : :.::. . . ::. . . : .:  :::. :...:.. . ... .  . . .:  :: 
NP_001 ALFLKGCTQLEDEALKYIGAHCPELVTLNLQTCLQITDEGL-ITICRGCHKLQSLCASGC
        170       180       190       200        210       220     

           300       310       320       330        340       350  
pF1KB4 RKNLQKSDLSTLVRRCPNLVHLDLSDSVMLKNDCFQEFFQ-LNYLQHLSLSRCYDIIPET
        .:.  . :..: . :: :  :...   .: .  :  . .  . :....: .: .:   :
NP_001 -SNITDAILNALGQNCPRLRILEVARCSQLTDVGFTTLARNCHELEKMDLEECVQITDST
          230       240       250       260       270       280    

             360          370       380       390       400        
pF1KB4 LLELG-EIPTLKTLQVFG---IVPDGTLQLLKEALPHLQINCSHFTTIARPTIGNKKNQE
       :..:. . : :..:..     :. ::  .: . :  : :.                    
NP_001 LIQLSIHCPRLQVLSLSHCELITDDGIRHLGNGACAHDQLEVIELDNCPLITDASLEHLK
          290       300       310       320       330       340    

      410       420                                                
pF1KB4 IWGIKCRLTLQKPSCL                                            
                                                                   
NP_001 SCHSLERIELYDCQQITRAGIKRLRTHLPNIKVHAYFAPVTPPPSVGGSRQRFCRCCIIL
          350       360       370       380       390       400    

>>XP_005257804 (OMIM: 609086) PREDICTED: F-box/LRR-repea  (441 aa)
 initn: 323 init1: 114 opt: 264  Z-score: 278.0  bits: 60.5 E(85289): 9.6e-09
Smith-Waterman score: 264; 28.1% identity (57.1% similar) in 310 aa overlap (100-388:65-361)

      70        80        90       100       110       120         
pF1KB4 LKSKGSDKDFVIVRRPKLNRENFPGVSWDSLPDELLLGIFSCLCLPELLKVSGVCKRWYR
                                     :: :::: ::: : .  : . . : . :  
XP_005 KMAPSRDRLLHFGFKATMFSNSDEAVINKKLPKELLLRIFSFLDVVTLCRCAQVSRAWNV
           40        50        60        70        80        90    

     130       140       150       160       170            180    
pF1KB4 LASDESLWQTLDLTGKNLHPDVTGRLLSQGVIAFRCPRSFMDQP-----LAEHFSPFRVQ
       :: : : :: .::   ... :. ::.. .  :. ::  .:. .      :.   . .:. 
XP_005 LALDGSNWQRIDLF--DFQRDIEGRVVEN--ISKRCG-GFLRKLSLRGCLGVGDNALRTF
          100         110       120          130       140         

          190       200       210             220            230   
pF1KB4 HMDLSNSVIEVSTLHGILSQCSKLQNLS----LEGLRLS--DPI----VNTLAKN-SNLV
        ..  :  ::: .:.:    :.:  .      :: : .:  : .    ...:... ..: 
XP_005 AQNCRN--IEVLNLNG----CTKTTDAEGCPLLEQLNISWCDQVTKDGIQALVRGCGGLK
     150         160           170       180       190       200   

           240       250       260       270       280       290   
pF1KB4 RLNLSGCSGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGY
        : :.::. . . ::. . . : .:  :::. :...:.. . ... .  . . .:  :: 
XP_005 ALFLKGCTQLEDEALKYIGAHCPELVTLNLQTCLQITDEGL-ITICRGCHKLQSLCASGC
           210       220       230       240        250       260  

           300       310       320       330        340       350  
pF1KB4 RKNLQKSDLSTLVRRCPNLVHLDLSDSVMLKNDCFQEFFQ-LNYLQHLSLSRCYDIIPET
        .:.  . :..: . :: :  :...   .: .  :  . .  . :....: .: .:   :
XP_005 -SNITDAILNALGQNCPRLRILEVARCSQLTDVGFTTLARNCHELEKMDLEECVQITDST
             270       280       290       300       310       320 

             360          370       380       390       400        
pF1KB4 LLELG-EIPTLKTLQVFG---IVPDGTLQLLKEALPHLQINCSHFTTIARPTIGNKKNQE
       :..:. . : :..:..     :. ::  .: . :  : :.                    
XP_005 LIQLSIHCPRLQVLSLSHCELITDDGIRHLGNGACAHDQLEVIELDNCPLITDASLEHLK
             330       340       350       360       370       380 

      410       420                                                
pF1KB4 IWGIKCRLTLQKPSCL                                            
                                                                   
XP_005 SCHSLERIELYDCQQITRAGIKRLRTHLPNIKVHAYFAPVTPPPSVGGSRQRFCRCCIIL
             390       400       410       420       430       440 




424 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 21:23:27 2016 done: Thu Nov  3 21:23:28 2016
 Total Scan time:  9.670 Total Display time:  0.010

Function used was FASTA [36.3.4 Apr, 2011]
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