FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4080, 338 aa 1>>>pF1KB4080 338 - 338 aa - 338 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.7616+/-0.000408; mu= 13.3851+/- 0.025 mean_var=71.8008+/-15.164, 0's: 0 Z-trim(111.6): 73 B-trim: 223 in 1/48 Lambda= 0.151359 statistics sampled from 20097 (20186) to 20097 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.613), E-opt: 0.2 (0.237), width: 16 Scan time: 7.070 The best scores are: opt bits E(85289) NP_065100 (OMIM: 616706) poly [ADP-ribose] polymer ( 338) 2365 525.9 4.8e-149 XP_005253768 (OMIM: 616706) PREDICTED: poly [ADP-r ( 331) 2309 513.7 2.2e-145 XP_011519273 (OMIM: 616706) PREDICTED: poly [ADP-r ( 331) 2309 513.7 2.2e-145 XP_016875159 (OMIM: 616706) PREDICTED: poly [ADP-r ( 331) 2309 513.7 2.2e-145 XP_011519275 (OMIM: 616706) PREDICTED: poly [ADP-r ( 331) 2309 513.7 2.2e-145 XP_011519272 (OMIM: 616706) PREDICTED: poly [ADP-r ( 331) 2309 513.7 2.2e-145 XP_016875160 (OMIM: 616706) PREDICTED: poly [ADP-r ( 257) 1733 387.8 1.3e-107 NP_001273451 (OMIM: 616706) poly [ADP-ribose] poly ( 257) 1733 387.8 1.3e-107 NP_001273450 (OMIM: 616706) poly [ADP-ribose] poly ( 257) 1733 387.8 1.3e-107 NP_073587 (OMIM: 612481) poly [ADP-ribose] polymer ( 701) 496 117.9 6.5e-26 NP_001171647 (OMIM: 612480) TCDD-inducible poly [A ( 657) 332 82.1 3.7e-15 NP_001171646 (OMIM: 612480) TCDD-inducible poly [A ( 657) 332 82.1 3.7e-15 NP_056323 (OMIM: 612480) TCDD-inducible poly [ADP- ( 657) 332 82.1 3.7e-15 NP_064504 (OMIM: 607312) zinc finger CCCH-type ant ( 902) 309 77.1 1.6e-13 XP_005250558 (OMIM: 607312) PREDICTED: zinc finger (1024) 309 77.1 1.8e-13 XP_011510781 (OMIM: 612066) PREDICTED: poly [ADP-r ( 425) 287 72.2 2.3e-12 XP_011510780 (OMIM: 612066) PREDICTED: poly [ADP-r ( 425) 287 72.2 2.3e-12 XP_016861281 (OMIM: 612066) PREDICTED: poly [ADP-r ( 425) 287 72.2 2.3e-12 NP_689828 (OMIM: 612066) poly [ADP-ribose] polymer ( 444) 287 72.2 2.4e-12 NP_001295250 (OMIM: 612066) poly [ADP-ribose] poly ( 375) 285 71.7 2.8e-12 XP_011510779 (OMIM: 612066) PREDICTED: poly [ADP-r ( 552) 287 72.2 2.9e-12 XP_005247217 (OMIM: 612066) PREDICTED: poly [ADP-r ( 602) 287 72.2 3.1e-12 XP_011510778 (OMIM: 612066) PREDICTED: poly [ADP-r ( 628) 287 72.2 3.2e-12 XP_011510777 (OMIM: 612066) PREDICTED: poly [ADP-r ( 638) 287 72.3 3.3e-12 NP_001106995 (OMIM: 612066) poly [ADP-ribose] poly ( 678) 287 72.3 3.4e-12 NP_001295249 (OMIM: 612066) poly [ADP-ribose] poly ( 483) 285 71.8 3.5e-12 XP_016861280 (OMIM: 612066) PREDICTED: poly [ADP-r ( 533) 285 71.8 3.8e-12 XP_005247216 (OMIM: 612066) PREDICTED: poly [ADP-r ( 609) 285 71.8 4.2e-12 NP_060024 (OMIM: 610028) poly [ADP-ribose] polymer (1801) 279 70.7 2.7e-11 NP_003738 (OMIM: 603303) tankyrase-1 [Homo sapiens (1327) 243 62.8 4.8e-09 XP_016872189 (OMIM: 607128) PREDICTED: tankyrase-2 ( 977) 237 61.4 9.2e-09 XP_016872188 (OMIM: 607128) PREDICTED: tankyrase-2 (1059) 237 61.4 9.8e-09 XP_016872186 (OMIM: 607128) PREDICTED: tankyrase-2 (1062) 237 61.4 9.9e-09 XP_016872187 (OMIM: 607128) PREDICTED: tankyrase-2 (1062) 237 61.4 9.9e-09 NP_079511 (OMIM: 607128) tankyrase-2 [Homo sapiens (1166) 237 61.4 1.1e-08 XP_016872185 (OMIM: 607128) PREDICTED: tankyrase-2 (1169) 237 61.4 1.1e-08 XP_011538515 (OMIM: 607128) PREDICTED: tankyrase-2 (1187) 237 61.4 1.1e-08 XP_005270242 (OMIM: 607128) PREDICTED: tankyrase-2 (1190) 237 61.4 1.1e-08 XP_011542148 (OMIM: 603303) PREDICTED: tankyrase-1 (1301) 206 54.7 1.3e-06 XP_006716326 (OMIM: 603303) PREDICTED: tankyrase-1 (1316) 206 54.7 1.3e-06 XP_011542147 (OMIM: 603303) PREDICTED: tankyrase-1 (1316) 206 54.7 1.3e-06 XP_011515638 (OMIM: 609564) PREDICTED: poly [ADP-r (1016) 192 51.6 8.6e-06 NP_116178 (OMIM: 609564) poly [ADP-ribose] polymer (1025) 192 51.6 8.7e-06 NP_001304824 (OMIM: 609564) poly [ADP-ribose] poly (1037) 192 51.6 8.8e-06 XP_011538517 (OMIM: 607128) PREDICTED: tankyrase-2 ( 695) 186 50.2 1.5e-05 XP_011542149 (OMIM: 603303) PREDICTED: tankyrase-1 (1223) 188 50.8 1.9e-05 >>NP_065100 (OMIM: 616706) poly [ADP-ribose] polymerase (338 aa) initn: 2365 init1: 2365 opt: 2365 Z-score: 2796.9 bits: 525.9 E(85289): 4.8e-149 Smith-Waterman score: 2365; 100.0% identity (100.0% similar) in 338 aa overlap (1-338:1-338) 10 20 30 40 50 60 pF1KB4 MWEANPEMFHKAEELFSKTTNNEVDDMDTSDTQWGWFYLAECGKWHMFQPDTNSQCSVSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 MWEANPEMFHKAEELFSKTTNNEVDDMDTSDTQWGWFYLAECGKWHMFQPDTNSQCSVSS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 EDIEKSFKTNPCGSISFTTSKFSYKIDFAEMKQMNLTTGKQRLIKRAPFSISAFSYICEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 EDIEKSFKTNPCGSISFTTSKFSYKIDFAEMKQMNLTTGKQRLIKRAPFSISAFSYICEN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 EAIPMPPHWENVNTQVPYQLIPLHNQTHEYNEVANLFGKTMDRNRIKRIQRIQNLDLWEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 EAIPMPPHWENVNTQVPYQLIPLHNQTHEYNEVANLFGKTMDRNRIKRIQRIQNLDLWEF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 FCRKKAQLKKKRGVPQINEQMLFHGTSSEFVEAICIHNFDWRINGIHGAVFGKGTYFARD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 FCRKKAQLKKKRGVPQINEQMLFHGTSSEFVEAICIHNFDWRINGIHGAVFGKGTYFARD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 AAYSSRFCKDDIKHGNTFQIHGVSLQQRHLFRTYKSMFLARVLIGDYINGDSKYMRPPSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 AAYSSRFCKDDIKHGNTFQIHGVSLQQRHLFRTYKSMFLARVLIGDYINGDSKYMRPPSK 250 260 270 280 290 300 310 320 330 pF1KB4 DGSYVNLYDSCVDDTWNPKIFVVFDANQIYPEYLIDFH :::::::::::::::::::::::::::::::::::::: NP_065 DGSYVNLYDSCVDDTWNPKIFVVFDANQIYPEYLIDFH 310 320 330 >>XP_005253768 (OMIM: 616706) PREDICTED: poly [ADP-ribos (331 aa) initn: 2309 init1: 2309 opt: 2309 Z-score: 2730.9 bits: 513.7 E(85289): 2.2e-145 Smith-Waterman score: 2309; 100.0% identity (100.0% similar) in 331 aa overlap (8-338:1-331) 10 20 30 40 50 60 pF1KB4 MWEANPEMFHKAEELFSKTTNNEVDDMDTSDTQWGWFYLAECGKWHMFQPDTNSQCSVSS ::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MFHKAEELFSKTTNNEVDDMDTSDTQWGWFYLAECGKWHMFQPDTNSQCSVSS 10 20 30 40 50 70 80 90 100 110 120 pF1KB4 EDIEKSFKTNPCGSISFTTSKFSYKIDFAEMKQMNLTTGKQRLIKRAPFSISAFSYICEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EDIEKSFKTNPCGSISFTTSKFSYKIDFAEMKQMNLTTGKQRLIKRAPFSISAFSYICEN 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB4 EAIPMPPHWENVNTQVPYQLIPLHNQTHEYNEVANLFGKTMDRNRIKRIQRIQNLDLWEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EAIPMPPHWENVNTQVPYQLIPLHNQTHEYNEVANLFGKTMDRNRIKRIQRIQNLDLWEF 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB4 FCRKKAQLKKKRGVPQINEQMLFHGTSSEFVEAICIHNFDWRINGIHGAVFGKGTYFARD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FCRKKAQLKKKRGVPQINEQMLFHGTSSEFVEAICIHNFDWRINGIHGAVFGKGTYFARD 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB4 AAYSSRFCKDDIKHGNTFQIHGVSLQQRHLFRTYKSMFLARVLIGDYINGDSKYMRPPSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AAYSSRFCKDDIKHGNTFQIHGVSLQQRHLFRTYKSMFLARVLIGDYINGDSKYMRPPSK 240 250 260 270 280 290 310 320 330 pF1KB4 DGSYVNLYDSCVDDTWNPKIFVVFDANQIYPEYLIDFH :::::::::::::::::::::::::::::::::::::: XP_005 DGSYVNLYDSCVDDTWNPKIFVVFDANQIYPEYLIDFH 300 310 320 330 >>XP_011519273 (OMIM: 616706) PREDICTED: poly [ADP-ribos (331 aa) initn: 2309 init1: 2309 opt: 2309 Z-score: 2730.9 bits: 513.7 E(85289): 2.2e-145 Smith-Waterman score: 2309; 100.0% identity (100.0% similar) in 331 aa overlap (8-338:1-331) 10 20 30 40 50 60 pF1KB4 MWEANPEMFHKAEELFSKTTNNEVDDMDTSDTQWGWFYLAECGKWHMFQPDTNSQCSVSS ::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MFHKAEELFSKTTNNEVDDMDTSDTQWGWFYLAECGKWHMFQPDTNSQCSVSS 10 20 30 40 50 70 80 90 100 110 120 pF1KB4 EDIEKSFKTNPCGSISFTTSKFSYKIDFAEMKQMNLTTGKQRLIKRAPFSISAFSYICEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EDIEKSFKTNPCGSISFTTSKFSYKIDFAEMKQMNLTTGKQRLIKRAPFSISAFSYICEN 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB4 EAIPMPPHWENVNTQVPYQLIPLHNQTHEYNEVANLFGKTMDRNRIKRIQRIQNLDLWEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EAIPMPPHWENVNTQVPYQLIPLHNQTHEYNEVANLFGKTMDRNRIKRIQRIQNLDLWEF 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB4 FCRKKAQLKKKRGVPQINEQMLFHGTSSEFVEAICIHNFDWRINGIHGAVFGKGTYFARD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FCRKKAQLKKKRGVPQINEQMLFHGTSSEFVEAICIHNFDWRINGIHGAVFGKGTYFARD 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB4 AAYSSRFCKDDIKHGNTFQIHGVSLQQRHLFRTYKSMFLARVLIGDYINGDSKYMRPPSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AAYSSRFCKDDIKHGNTFQIHGVSLQQRHLFRTYKSMFLARVLIGDYINGDSKYMRPPSK 240 250 260 270 280 290 310 320 330 pF1KB4 DGSYVNLYDSCVDDTWNPKIFVVFDANQIYPEYLIDFH :::::::::::::::::::::::::::::::::::::: XP_011 DGSYVNLYDSCVDDTWNPKIFVVFDANQIYPEYLIDFH 300 310 320 330 >>XP_016875159 (OMIM: 616706) PREDICTED: poly [ADP-ribos (331 aa) initn: 2309 init1: 2309 opt: 2309 Z-score: 2730.9 bits: 513.7 E(85289): 2.2e-145 Smith-Waterman score: 2309; 100.0% identity (100.0% similar) in 331 aa overlap (8-338:1-331) 10 20 30 40 50 60 pF1KB4 MWEANPEMFHKAEELFSKTTNNEVDDMDTSDTQWGWFYLAECGKWHMFQPDTNSQCSVSS ::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MFHKAEELFSKTTNNEVDDMDTSDTQWGWFYLAECGKWHMFQPDTNSQCSVSS 10 20 30 40 50 70 80 90 100 110 120 pF1KB4 EDIEKSFKTNPCGSISFTTSKFSYKIDFAEMKQMNLTTGKQRLIKRAPFSISAFSYICEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EDIEKSFKTNPCGSISFTTSKFSYKIDFAEMKQMNLTTGKQRLIKRAPFSISAFSYICEN 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB4 EAIPMPPHWENVNTQVPYQLIPLHNQTHEYNEVANLFGKTMDRNRIKRIQRIQNLDLWEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EAIPMPPHWENVNTQVPYQLIPLHNQTHEYNEVANLFGKTMDRNRIKRIQRIQNLDLWEF 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB4 FCRKKAQLKKKRGVPQINEQMLFHGTSSEFVEAICIHNFDWRINGIHGAVFGKGTYFARD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FCRKKAQLKKKRGVPQINEQMLFHGTSSEFVEAICIHNFDWRINGIHGAVFGKGTYFARD 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB4 AAYSSRFCKDDIKHGNTFQIHGVSLQQRHLFRTYKSMFLARVLIGDYINGDSKYMRPPSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AAYSSRFCKDDIKHGNTFQIHGVSLQQRHLFRTYKSMFLARVLIGDYINGDSKYMRPPSK 240 250 260 270 280 290 310 320 330 pF1KB4 DGSYVNLYDSCVDDTWNPKIFVVFDANQIYPEYLIDFH :::::::::::::::::::::::::::::::::::::: XP_016 DGSYVNLYDSCVDDTWNPKIFVVFDANQIYPEYLIDFH 300 310 320 330 >>XP_011519275 (OMIM: 616706) PREDICTED: poly [ADP-ribos (331 aa) initn: 2309 init1: 2309 opt: 2309 Z-score: 2730.9 bits: 513.7 E(85289): 2.2e-145 Smith-Waterman score: 2309; 100.0% identity (100.0% similar) in 331 aa overlap (8-338:1-331) 10 20 30 40 50 60 pF1KB4 MWEANPEMFHKAEELFSKTTNNEVDDMDTSDTQWGWFYLAECGKWHMFQPDTNSQCSVSS ::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MFHKAEELFSKTTNNEVDDMDTSDTQWGWFYLAECGKWHMFQPDTNSQCSVSS 10 20 30 40 50 70 80 90 100 110 120 pF1KB4 EDIEKSFKTNPCGSISFTTSKFSYKIDFAEMKQMNLTTGKQRLIKRAPFSISAFSYICEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EDIEKSFKTNPCGSISFTTSKFSYKIDFAEMKQMNLTTGKQRLIKRAPFSISAFSYICEN 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB4 EAIPMPPHWENVNTQVPYQLIPLHNQTHEYNEVANLFGKTMDRNRIKRIQRIQNLDLWEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EAIPMPPHWENVNTQVPYQLIPLHNQTHEYNEVANLFGKTMDRNRIKRIQRIQNLDLWEF 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB4 FCRKKAQLKKKRGVPQINEQMLFHGTSSEFVEAICIHNFDWRINGIHGAVFGKGTYFARD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FCRKKAQLKKKRGVPQINEQMLFHGTSSEFVEAICIHNFDWRINGIHGAVFGKGTYFARD 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB4 AAYSSRFCKDDIKHGNTFQIHGVSLQQRHLFRTYKSMFLARVLIGDYINGDSKYMRPPSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AAYSSRFCKDDIKHGNTFQIHGVSLQQRHLFRTYKSMFLARVLIGDYINGDSKYMRPPSK 240 250 260 270 280 290 310 320 330 pF1KB4 DGSYVNLYDSCVDDTWNPKIFVVFDANQIYPEYLIDFH :::::::::::::::::::::::::::::::::::::: XP_011 DGSYVNLYDSCVDDTWNPKIFVVFDANQIYPEYLIDFH 300 310 320 330 >>XP_011519272 (OMIM: 616706) PREDICTED: poly [ADP-ribos (331 aa) initn: 2309 init1: 2309 opt: 2309 Z-score: 2730.9 bits: 513.7 E(85289): 2.2e-145 Smith-Waterman score: 2309; 100.0% identity (100.0% similar) in 331 aa overlap (8-338:1-331) 10 20 30 40 50 60 pF1KB4 MWEANPEMFHKAEELFSKTTNNEVDDMDTSDTQWGWFYLAECGKWHMFQPDTNSQCSVSS ::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MFHKAEELFSKTTNNEVDDMDTSDTQWGWFYLAECGKWHMFQPDTNSQCSVSS 10 20 30 40 50 70 80 90 100 110 120 pF1KB4 EDIEKSFKTNPCGSISFTTSKFSYKIDFAEMKQMNLTTGKQRLIKRAPFSISAFSYICEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EDIEKSFKTNPCGSISFTTSKFSYKIDFAEMKQMNLTTGKQRLIKRAPFSISAFSYICEN 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB4 EAIPMPPHWENVNTQVPYQLIPLHNQTHEYNEVANLFGKTMDRNRIKRIQRIQNLDLWEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EAIPMPPHWENVNTQVPYQLIPLHNQTHEYNEVANLFGKTMDRNRIKRIQRIQNLDLWEF 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB4 FCRKKAQLKKKRGVPQINEQMLFHGTSSEFVEAICIHNFDWRINGIHGAVFGKGTYFARD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FCRKKAQLKKKRGVPQINEQMLFHGTSSEFVEAICIHNFDWRINGIHGAVFGKGTYFARD 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB4 AAYSSRFCKDDIKHGNTFQIHGVSLQQRHLFRTYKSMFLARVLIGDYINGDSKYMRPPSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AAYSSRFCKDDIKHGNTFQIHGVSLQQRHLFRTYKSMFLARVLIGDYINGDSKYMRPPSK 240 250 260 270 280 290 310 320 330 pF1KB4 DGSYVNLYDSCVDDTWNPKIFVVFDANQIYPEYLIDFH :::::::::::::::::::::::::::::::::::::: XP_011 DGSYVNLYDSCVDDTWNPKIFVVFDANQIYPEYLIDFH 300 310 320 330 >>XP_016875160 (OMIM: 616706) PREDICTED: poly [ADP-ribos (257 aa) initn: 1733 init1: 1733 opt: 1733 Z-score: 2052.9 bits: 387.8 E(85289): 1.3e-107 Smith-Waterman score: 1733; 99.6% identity (100.0% similar) in 250 aa overlap (89-338:8-257) 60 70 80 90 100 110 pF1KB4 SSEDIEKSFKTNPCGSISFTTSKFSYKIDFAEMKQMNLTTGKQRLIKRAPFSISAFSYIC .::::::::::::::::::::::::::::: XP_016 MWEVAHVSEMKQMNLTTGKQRLIKRAPFSISAFSYIC 10 20 30 120 130 140 150 160 170 pF1KB4 ENEAIPMPPHWENVNTQVPYQLIPLHNQTHEYNEVANLFGKTMDRNRIKRIQRIQNLDLW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ENEAIPMPPHWENVNTQVPYQLIPLHNQTHEYNEVANLFGKTMDRNRIKRIQRIQNLDLW 40 50 60 70 80 90 180 190 200 210 220 230 pF1KB4 EFFCRKKAQLKKKRGVPQINEQMLFHGTSSEFVEAICIHNFDWRINGIHGAVFGKGTYFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EFFCRKKAQLKKKRGVPQINEQMLFHGTSSEFVEAICIHNFDWRINGIHGAVFGKGTYFA 100 110 120 130 140 150 240 250 260 270 280 290 pF1KB4 RDAAYSSRFCKDDIKHGNTFQIHGVSLQQRHLFRTYKSMFLARVLIGDYINGDSKYMRPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RDAAYSSRFCKDDIKHGNTFQIHGVSLQQRHLFRTYKSMFLARVLIGDYINGDSKYMRPP 160 170 180 190 200 210 300 310 320 330 pF1KB4 SKDGSYVNLYDSCVDDTWNPKIFVVFDANQIYPEYLIDFH :::::::::::::::::::::::::::::::::::::::: XP_016 SKDGSYVNLYDSCVDDTWNPKIFVVFDANQIYPEYLIDFH 220 230 240 250 >>NP_001273451 (OMIM: 616706) poly [ADP-ribose] polymera (257 aa) initn: 1733 init1: 1733 opt: 1733 Z-score: 2052.9 bits: 387.8 E(85289): 1.3e-107 Smith-Waterman score: 1733; 99.6% identity (100.0% similar) in 250 aa overlap (89-338:8-257) 60 70 80 90 100 110 pF1KB4 SSEDIEKSFKTNPCGSISFTTSKFSYKIDFAEMKQMNLTTGKQRLIKRAPFSISAFSYIC .::::::::::::::::::::::::::::: NP_001 MWEVAHVSEMKQMNLTTGKQRLIKRAPFSISAFSYIC 10 20 30 120 130 140 150 160 170 pF1KB4 ENEAIPMPPHWENVNTQVPYQLIPLHNQTHEYNEVANLFGKTMDRNRIKRIQRIQNLDLW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ENEAIPMPPHWENVNTQVPYQLIPLHNQTHEYNEVANLFGKTMDRNRIKRIQRIQNLDLW 40 50 60 70 80 90 180 190 200 210 220 230 pF1KB4 EFFCRKKAQLKKKRGVPQINEQMLFHGTSSEFVEAICIHNFDWRINGIHGAVFGKGTYFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EFFCRKKAQLKKKRGVPQINEQMLFHGTSSEFVEAICIHNFDWRINGIHGAVFGKGTYFA 100 110 120 130 140 150 240 250 260 270 280 290 pF1KB4 RDAAYSSRFCKDDIKHGNTFQIHGVSLQQRHLFRTYKSMFLARVLIGDYINGDSKYMRPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RDAAYSSRFCKDDIKHGNTFQIHGVSLQQRHLFRTYKSMFLARVLIGDYINGDSKYMRPP 160 170 180 190 200 210 300 310 320 330 pF1KB4 SKDGSYVNLYDSCVDDTWNPKIFVVFDANQIYPEYLIDFH :::::::::::::::::::::::::::::::::::::::: NP_001 SKDGSYVNLYDSCVDDTWNPKIFVVFDANQIYPEYLIDFH 220 230 240 250 >>NP_001273450 (OMIM: 616706) poly [ADP-ribose] polymera (257 aa) initn: 1733 init1: 1733 opt: 1733 Z-score: 2052.9 bits: 387.8 E(85289): 1.3e-107 Smith-Waterman score: 1733; 99.6% identity (100.0% similar) in 250 aa overlap (89-338:8-257) 60 70 80 90 100 110 pF1KB4 SSEDIEKSFKTNPCGSISFTTSKFSYKIDFAEMKQMNLTTGKQRLIKRAPFSISAFSYIC .::::::::::::::::::::::::::::: NP_001 MWEVAHVSEMKQMNLTTGKQRLIKRAPFSISAFSYIC 10 20 30 120 130 140 150 160 170 pF1KB4 ENEAIPMPPHWENVNTQVPYQLIPLHNQTHEYNEVANLFGKTMDRNRIKRIQRIQNLDLW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ENEAIPMPPHWENVNTQVPYQLIPLHNQTHEYNEVANLFGKTMDRNRIKRIQRIQNLDLW 40 50 60 70 80 90 180 190 200 210 220 230 pF1KB4 EFFCRKKAQLKKKRGVPQINEQMLFHGTSSEFVEAICIHNFDWRINGIHGAVFGKGTYFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EFFCRKKAQLKKKRGVPQINEQMLFHGTSSEFVEAICIHNFDWRINGIHGAVFGKGTYFA 100 110 120 130 140 150 240 250 260 270 280 290 pF1KB4 RDAAYSSRFCKDDIKHGNTFQIHGVSLQQRHLFRTYKSMFLARVLIGDYINGDSKYMRPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RDAAYSSRFCKDDIKHGNTFQIHGVSLQQRHLFRTYKSMFLARVLIGDYINGDSKYMRPP 160 170 180 190 200 210 300 310 320 330 pF1KB4 SKDGSYVNLYDSCVDDTWNPKIFVVFDANQIYPEYLIDFH :::::::::::::::::::::::::::::::::::::::: NP_001 SKDGSYVNLYDSCVDDTWNPKIFVVFDANQIYPEYLIDFH 220 230 240 250 >>NP_073587 (OMIM: 612481) poly [ADP-ribose] polymerase (701 aa) initn: 657 init1: 423 opt: 496 Z-score: 586.2 bits: 117.9 E(85289): 6.5e-26 Smith-Waterman score: 763; 36.5% identity (66.6% similar) in 323 aa overlap (32-337:375-677) 10 20 30 40 50 pF1KB4 WEANPEMFHKAEELFSKTTNNEVDDMDTSDTQWGWFYLAECGKWHMF--QPDTNSQCSVS :.: :.. : :.:. . : .. .:: NP_073 NFNAMTYGATQARRLSTASSVTKPPHFILTTDWIWYWSDEFGSWQEYGRQGTVHPVTTVS 350 360 370 380 390 400 60 70 80 90 100 110 pF1KB4 SEDIEKSF-------KTNPCGSISFTTSKFSYKIDFAEMKQMNLTTGKQRLIKRAPFSIS : :.::.. . . ....: ..: .:..:: . : ::. : . . : : .: NP_073 SSDVEKAYLAYCTPGSDGQAATLKFQAGKHNYELDFKAFVQKNLVYGTTKKVCRRPKYVS 410 420 430 440 450 460 120 130 140 150 160 pF1KB4 ---AFSYICENEAIP----MPPHWENVNTQVP-YQLIPLHNQTHEYNEVANLFGKTMDRN . .. : .: .: .:.. : .: : : ....::..: :::..:. NP_073 PQDVTTMQTCNTKFPGPKSIPDYWDSSALPDPGFQKITLSSSSEEYQKVWNLFNRTLPFY 470 480 490 500 510 520 170 180 190 200 210 220 pF1KB4 RIKRIQRIQNLDLWEFFCRKKAQLKKKRGVPQINEQMLFHGTSSEFVEAICIHNFDWRIN ...:.:.::: ::: . .:.:..:. : ..:..::::::. ::.::: .:::::. NP_073 FVQKIERVQNLALWEVYQWQKGQMQKQNGGKAVDERQLFHGTSAIFVDAICQQNFDWRVC 530 540 550 560 570 580 230 240 250 260 270 280 pF1KB4 GIHGAVFGKGTYFARDAAYSSRFCKDDIKHGNTFQIHGVSLQQRHLFRTYKSMFLARVLI :.::. .:::.::::::::: .. :.: : : .:::::::. NP_073 GVHGTSYGKGSYFARDAAYSHHYSKSDT------QTH--------------TMFLARVLV 590 600 610 620 290 300 310 320 330 pF1KB4 GDYINGDSKYMRPPSKDGSYVNLYDSCVDDTWNPKIFVVFDANQIYPEYLIDFH :... :.....:::.:.: .:::::... .:.:::.:. .:.::::.:.. NP_073 GEFVRGNASFVRPPAKEGWSNAFYDSCVNSVSDPSIFVIFEKHQVYPEYVIQYTTSSKPS 630 640 650 660 670 680 NP_073 VTPSILLALGSLFSSRQ 690 700 338 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 05:35:41 2016 done: Sat Nov 5 05:35:42 2016 Total Scan time: 7.070 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]