FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4099, 452 aa 1>>>pF1KB4099 452 - 452 aa - 452 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.3968+/-0.000365; mu= 17.1104+/- 0.023 mean_var=67.1721+/-13.522, 0's: 0 Z-trim(113.3): 162 B-trim: 291 in 1/51 Lambda= 0.156488 statistics sampled from 22472 (22646) to 22472 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.636), E-opt: 0.2 (0.266), width: 16 Scan time: 7.130 The best scores are: opt bits E(85289) NP_001112357 (OMIM: 305990) glycine receptor subun ( 452) 3035 694.3 1.8e-199 NP_002054 (OMIM: 305990) glycine receptor subunit ( 452) 3035 694.3 1.8e-199 NP_001112358 (OMIM: 305990) glycine receptor subun ( 452) 3029 692.9 4.5e-199 XP_016884916 (OMIM: 305990) PREDICTED: glycine rec ( 452) 3029 692.9 4.5e-199 XP_011543798 (OMIM: 305990) PREDICTED: glycine rec ( 436) 2893 662.2 7.6e-190 XP_011543797 (OMIM: 305990) PREDICTED: glycine rec ( 436) 2893 662.2 7.6e-190 XP_006724550 (OMIM: 305990) PREDICTED: glycine rec ( 436) 2893 662.2 7.6e-190 XP_016884917 (OMIM: 305990) PREDICTED: glycine rec ( 363) 2437 559.2 6.4e-159 XP_016884918 (OMIM: 305990) PREDICTED: glycine rec ( 363) 2437 559.2 6.4e-159 NP_001165413 (OMIM: 305990) glycine receptor subun ( 363) 2437 559.2 6.4e-159 NP_001036008 (OMIM: 600421) glycine receptor subun ( 449) 2408 552.7 7.2e-157 NP_000162 (OMIM: 138491,149400) glycine receptor s ( 449) 2331 535.3 1.2e-151 XP_016864838 (OMIM: 138491,149400) PREDICTED: glyc ( 465) 2330 535.1 1.5e-151 NP_001139512 (OMIM: 138491,149400) glycine recepto ( 457) 2087 480.2 4.8e-135 NP_006520 (OMIM: 600421) glycine receptor subunit ( 464) 2024 466.0 9.2e-131 XP_016864119 (OMIM: 600421) PREDICTED: glycine rec ( 424) 2011 463.1 6.5e-130 NP_001278929 (OMIM: 138491,149400) glycine recepto ( 366) 2008 462.4 9.2e-130 XP_011530569 (OMIM: 600421) PREDICTED: glycine rec ( 313) 1731 399.8 5.4e-111 NP_000815 (OMIM: 138492,614619) glycine receptor s ( 497) 1220 284.5 4.3e-76 NP_001159532 (OMIM: 138492,614619) glycine recepto ( 497) 1220 284.5 4.3e-76 XP_016863523 (OMIM: 138492,614619) PREDICTED: glyc ( 399) 1040 243.8 6.1e-64 NP_001159533 (OMIM: 138492,614619) glycine recepto ( 303) 1023 239.9 6.9e-63 XP_016863524 (OMIM: 138492,614619) PREDICTED: glyc ( 303) 1023 239.9 6.9e-63 XP_011530570 (OMIM: 600421) PREDICTED: glycine rec ( 269) 1003 235.4 1.4e-61 XP_016863471 (OMIM: 103780,137140) PREDICTED: gamm ( 451) 973 228.7 2.4e-59 XP_016863472 (OMIM: 103780,137140) PREDICTED: gamm ( 451) 973 228.7 2.4e-59 NP_001107647 (OMIM: 103780,137140) gamma-aminobuty ( 451) 973 228.7 2.4e-59 NP_000798 (OMIM: 103780,137140) gamma-aminobutyric ( 451) 973 228.7 2.4e-59 NP_068712 (OMIM: 137192,612269,617113) gamma-amino ( 473) 966 227.2 7.5e-59 NP_000803 (OMIM: 137190,617153) gamma-aminobutyric ( 474) 963 226.5 1.2e-58 NP_001121116 (OMIM: 137160,611136,615744) gamma-am ( 456) 961 226.0 1.6e-58 NP_001121117 (OMIM: 137160,611136,615744) gamma-am ( 456) 961 226.0 1.6e-58 NP_001121120 (OMIM: 137160,611136,615744) gamma-am ( 456) 961 226.0 1.6e-58 NP_001121115 (OMIM: 137160,611136,615744) gamma-am ( 456) 961 226.0 1.6e-58 NP_000797 (OMIM: 137160,611136,615744) gamma-amino ( 456) 961 226.0 1.6e-58 NP_000805 (OMIM: 137192,612269,617113) gamma-amino ( 473) 959 225.6 2.2e-58 NP_001158509 (OMIM: 137142) gamma-aminobutyric aci ( 462) 953 224.2 5.6e-58 XP_006720522 (OMIM: 137142) PREDICTED: gamma-amino ( 462) 953 224.2 5.6e-58 XP_005268315 (OMIM: 137142) PREDICTED: gamma-amino ( 462) 953 224.2 5.6e-58 NP_000801 (OMIM: 137142) gamma-aminobutyric acid r ( 462) 953 224.2 5.6e-58 NP_000804 (OMIM: 600232) gamma-aminobutyric acid r ( 474) 947 222.9 1.5e-57 NP_068711 (OMIM: 600232) gamma-aminobutyric acid r ( 512) 947 222.9 1.6e-57 NP_000806 (OMIM: 137163,613060) gamma-aminobutyric ( 452) 926 218.1 3.8e-56 XP_011539496 (OMIM: 137163,613060) PREDICTED: gamm ( 465) 926 218.1 3.9e-56 XP_016856425 (OMIM: 137163,613060) PREDICTED: gamm ( 687) 926 218.2 5.4e-56 NP_055026 (OMIM: 602729) gamma-aminobutyric acid r ( 440) 922 217.2 6.9e-56 NP_000800 (OMIM: 137141) gamma-aminobutyric acid r ( 554) 907 213.9 8.8e-55 NP_001243632 (OMIM: 137161) gamma-aminobutyric aci ( 462) 906 213.6 8.8e-55 NP_002033 (OMIM: 137161) gamma-aminobutyric acid r ( 479) 906 213.6 9.1e-55 NP_001191195 (OMIM: 137141) gamma-aminobutyric aci ( 535) 904 213.2 1.4e-54 >>NP_001112357 (OMIM: 305990) glycine receptor subunit a (452 aa) initn: 3035 init1: 3035 opt: 3035 Z-score: 3702.3 bits: 694.3 E(85289): 1.8e-199 Smith-Waterman score: 3035; 100.0% identity (100.0% similar) in 452 aa overlap (1-452:1-452) 10 20 30 40 50 60 pF1KB4 MNRQLVNILTALFAFFLETNHFRTAFCKDHDSRSGKQPSQTLSPSDFLDKLMGRTSGYDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MNRQLVNILTALFAFFLETNHFRTAFCKDHDSRSGKQPSQTLSPSDFLDKLMGRTSGYDA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 RIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 PSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 MDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFILKEEKELGYCTKHYNTGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFILKEEKELGYCTKHYNTGK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 FTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 SSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFLRLRRRQKRQNK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFLRLRRRQKRQNK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 EEDVTRESRFNFSGYGMGHCLQVKDGTAVKATPANPLPQPPKDGDAIKKKFVDRAKRIDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EEDVTRESRFNFSGYGMGHCLQVKDGTAVKATPANPLPQPPKDGDAIKKKFVDRAKRIDT 370 380 390 400 410 420 430 440 450 pF1KB4 ISRAAFPLAFLIFNIFYWITYKIIRHEDVHKK :::::::::::::::::::::::::::::::: NP_001 ISRAAFPLAFLIFNIFYWITYKIIRHEDVHKK 430 440 450 >>NP_002054 (OMIM: 305990) glycine receptor subunit alph (452 aa) initn: 3035 init1: 3035 opt: 3035 Z-score: 3702.3 bits: 694.3 E(85289): 1.8e-199 Smith-Waterman score: 3035; 100.0% identity (100.0% similar) in 452 aa overlap (1-452:1-452) 10 20 30 40 50 60 pF1KB4 MNRQLVNILTALFAFFLETNHFRTAFCKDHDSRSGKQPSQTLSPSDFLDKLMGRTSGYDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MNRQLVNILTALFAFFLETNHFRTAFCKDHDSRSGKQPSQTLSPSDFLDKLMGRTSGYDA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 RIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 RIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 PSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 PSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 MDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFILKEEKELGYCTKHYNTGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFILKEEKELGYCTKHYNTGK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 FTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 FTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 SSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFLRLRRRQKRQNK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 SSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFLRLRRRQKRQNK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 EEDVTRESRFNFSGYGMGHCLQVKDGTAVKATPANPLPQPPKDGDAIKKKFVDRAKRIDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 EEDVTRESRFNFSGYGMGHCLQVKDGTAVKATPANPLPQPPKDGDAIKKKFVDRAKRIDT 370 380 390 400 410 420 430 440 450 pF1KB4 ISRAAFPLAFLIFNIFYWITYKIIRHEDVHKK :::::::::::::::::::::::::::::::: NP_002 ISRAAFPLAFLIFNIFYWITYKIIRHEDVHKK 430 440 450 >>NP_001112358 (OMIM: 305990) glycine receptor subunit a (452 aa) initn: 3029 init1: 3029 opt: 3029 Z-score: 3695.0 bits: 692.9 E(85289): 4.5e-199 Smith-Waterman score: 3029; 99.6% identity (100.0% similar) in 452 aa overlap (1-452:1-452) 10 20 30 40 50 60 pF1KB4 MNRQLVNILTALFAFFLETNHFRTAFCKDHDSRSGKQPSQTLSPSDFLDKLMGRTSGYDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MNRQLVNILTALFAFFLETNHFRTAFCKDHDSRSGKQPSQTLSPSDFLDKLMGRTSGYDA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 RIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLD ::::::::::::::::::::::::..:::::::::::::::::::::::::::::::::: NP_001 RIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 PSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 MDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFILKEEKELGYCTKHYNTGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFILKEEKELGYCTKHYNTGK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 FTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 SSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFLRLRRRQKRQNK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFLRLRRRQKRQNK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 EEDVTRESRFNFSGYGMGHCLQVKDGTAVKATPANPLPQPPKDGDAIKKKFVDRAKRIDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EEDVTRESRFNFSGYGMGHCLQVKDGTAVKATPANPLPQPPKDGDAIKKKFVDRAKRIDT 370 380 390 400 410 420 430 440 450 pF1KB4 ISRAAFPLAFLIFNIFYWITYKIIRHEDVHKK :::::::::::::::::::::::::::::::: NP_001 ISRAAFPLAFLIFNIFYWITYKIIRHEDVHKK 430 440 450 >>XP_016884916 (OMIM: 305990) PREDICTED: glycine recepto (452 aa) initn: 3029 init1: 3029 opt: 3029 Z-score: 3695.0 bits: 692.9 E(85289): 4.5e-199 Smith-Waterman score: 3029; 99.6% identity (100.0% similar) in 452 aa overlap (1-452:1-452) 10 20 30 40 50 60 pF1KB4 MNRQLVNILTALFAFFLETNHFRTAFCKDHDSRSGKQPSQTLSPSDFLDKLMGRTSGYDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MNRQLVNILTALFAFFLETNHFRTAFCKDHDSRSGKQPSQTLSPSDFLDKLMGRTSGYDA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 RIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLD ::::::::::::::::::::::::..:::::::::::::::::::::::::::::::::: XP_016 RIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 PSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 MDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFILKEEKELGYCTKHYNTGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFILKEEKELGYCTKHYNTGK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 FTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 SSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFLRLRRRQKRQNK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFLRLRRRQKRQNK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 EEDVTRESRFNFSGYGMGHCLQVKDGTAVKATPANPLPQPPKDGDAIKKKFVDRAKRIDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEDVTRESRFNFSGYGMGHCLQVKDGTAVKATPANPLPQPPKDGDAIKKKFVDRAKRIDT 370 380 390 400 410 420 430 440 450 pF1KB4 ISRAAFPLAFLIFNIFYWITYKIIRHEDVHKK :::::::::::::::::::::::::::::::: XP_016 ISRAAFPLAFLIFNIFYWITYKIIRHEDVHKK 430 440 450 >>XP_011543798 (OMIM: 305990) PREDICTED: glycine recepto (436 aa) initn: 2888 init1: 2888 opt: 2893 Z-score: 3529.3 bits: 662.2 E(85289): 7.6e-190 Smith-Waterman score: 2893; 99.5% identity (99.8% similar) in 433 aa overlap (21-452:4-436) 10 20 30 40 50 pF1KB4 MNRQLVNILTALFAFFLETNHFR-TAFCKDHDSRSGKQPSQTLSPSDFLDKLMGRTSGYD :.: :::::::::::::::::::::::::::::::::::: XP_011 MNLHMRMTAFCKDHDSRSGKQPSQTLSPSDFLDKLMGRTSGYD 10 20 30 40 60 70 80 90 100 110 pF1KB4 ARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDL 50 60 70 80 90 100 120 130 140 150 160 170 pF1KB4 DPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNF 110 120 130 140 150 160 180 190 200 210 220 230 pF1KB4 PMDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFILKEEKELGYCTKHYNTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PMDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFILKEEKELGYCTKHYNTG 170 180 190 200 210 220 240 250 260 270 280 290 pF1KB4 KFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTT 230 240 250 260 270 280 300 310 320 330 340 350 pF1KB4 QSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFLRLRRRQKRQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFLRLRRRQKRQN 290 300 310 320 330 340 360 370 380 390 400 410 pF1KB4 KEEDVTRESRFNFSGYGMGHCLQVKDGTAVKATPANPLPQPPKDGDAIKKKFVDRAKRID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KEEDVTRESRFNFSGYGMGHCLQVKDGTAVKATPANPLPQPPKDGDAIKKKFVDRAKRID 350 360 370 380 390 400 420 430 440 450 pF1KB4 TISRAAFPLAFLIFNIFYWITYKIIRHEDVHKK ::::::::::::::::::::::::::::::::: XP_011 TISRAAFPLAFLIFNIFYWITYKIIRHEDVHKK 410 420 430 >>XP_011543797 (OMIM: 305990) PREDICTED: glycine recepto (436 aa) initn: 2888 init1: 2888 opt: 2893 Z-score: 3529.3 bits: 662.2 E(85289): 7.6e-190 Smith-Waterman score: 2893; 99.5% identity (99.8% similar) in 433 aa overlap (21-452:4-436) 10 20 30 40 50 pF1KB4 MNRQLVNILTALFAFFLETNHFR-TAFCKDHDSRSGKQPSQTLSPSDFLDKLMGRTSGYD :.: :::::::::::::::::::::::::::::::::::: XP_011 MNLHMRMTAFCKDHDSRSGKQPSQTLSPSDFLDKLMGRTSGYD 10 20 30 40 60 70 80 90 100 110 pF1KB4 ARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDL 50 60 70 80 90 100 120 130 140 150 160 170 pF1KB4 DPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNF 110 120 130 140 150 160 180 190 200 210 220 230 pF1KB4 PMDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFILKEEKELGYCTKHYNTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PMDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFILKEEKELGYCTKHYNTG 170 180 190 200 210 220 240 250 260 270 280 290 pF1KB4 KFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTT 230 240 250 260 270 280 300 310 320 330 340 350 pF1KB4 QSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFLRLRRRQKRQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFLRLRRRQKRQN 290 300 310 320 330 340 360 370 380 390 400 410 pF1KB4 KEEDVTRESRFNFSGYGMGHCLQVKDGTAVKATPANPLPQPPKDGDAIKKKFVDRAKRID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KEEDVTRESRFNFSGYGMGHCLQVKDGTAVKATPANPLPQPPKDGDAIKKKFVDRAKRID 350 360 370 380 390 400 420 430 440 450 pF1KB4 TISRAAFPLAFLIFNIFYWITYKIIRHEDVHKK ::::::::::::::::::::::::::::::::: XP_011 TISRAAFPLAFLIFNIFYWITYKIIRHEDVHKK 410 420 430 >>XP_006724550 (OMIM: 305990) PREDICTED: glycine recepto (436 aa) initn: 2888 init1: 2888 opt: 2893 Z-score: 3529.3 bits: 662.2 E(85289): 7.6e-190 Smith-Waterman score: 2893; 99.5% identity (99.8% similar) in 433 aa overlap (21-452:4-436) 10 20 30 40 50 pF1KB4 MNRQLVNILTALFAFFLETNHFR-TAFCKDHDSRSGKQPSQTLSPSDFLDKLMGRTSGYD :.: :::::::::::::::::::::::::::::::::::: XP_006 MNLHMRMTAFCKDHDSRSGKQPSQTLSPSDFLDKLMGRTSGYD 10 20 30 40 60 70 80 90 100 110 pF1KB4 ARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDL 50 60 70 80 90 100 120 130 140 150 160 170 pF1KB4 DPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNF 110 120 130 140 150 160 180 190 200 210 220 230 pF1KB4 PMDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFILKEEKELGYCTKHYNTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PMDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFILKEEKELGYCTKHYNTG 170 180 190 200 210 220 240 250 260 270 280 290 pF1KB4 KFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTT 230 240 250 260 270 280 300 310 320 330 340 350 pF1KB4 QSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFLRLRRRQKRQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFLRLRRRQKRQN 290 300 310 320 330 340 360 370 380 390 400 410 pF1KB4 KEEDVTRESRFNFSGYGMGHCLQVKDGTAVKATPANPLPQPPKDGDAIKKKFVDRAKRID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KEEDVTRESRFNFSGYGMGHCLQVKDGTAVKATPANPLPQPPKDGDAIKKKFVDRAKRID 350 360 370 380 390 400 420 430 440 450 pF1KB4 TISRAAFPLAFLIFNIFYWITYKIIRHEDVHKK ::::::::::::::::::::::::::::::::: XP_006 TISRAAFPLAFLIFNIFYWITYKIIRHEDVHKK 410 420 430 >>XP_016884917 (OMIM: 305990) PREDICTED: glycine recepto (363 aa) initn: 2437 init1: 2437 opt: 2437 Z-score: 2974.1 bits: 559.2 E(85289): 6.4e-159 Smith-Waterman score: 2437; 100.0% identity (100.0% similar) in 363 aa overlap (90-452:1-363) 60 70 80 90 100 110 pF1KB4 ARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDL :::::::::::::::::::::::::::::: XP_016 MDYRVNIFLRQQWNDSRLAYSEYPDDSLDL 10 20 30 120 130 140 150 160 170 pF1KB4 DPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNF 40 50 60 70 80 90 180 190 200 210 220 230 pF1KB4 PMDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFILKEEKELGYCTKHYNTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PMDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFILKEEKELGYCTKHYNTG 100 110 120 130 140 150 240 250 260 270 280 290 pF1KB4 KFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTT 160 170 180 190 200 210 300 310 320 330 340 350 pF1KB4 QSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFLRLRRRQKRQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFLRLRRRQKRQN 220 230 240 250 260 270 360 370 380 390 400 410 pF1KB4 KEEDVTRESRFNFSGYGMGHCLQVKDGTAVKATPANPLPQPPKDGDAIKKKFVDRAKRID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KEEDVTRESRFNFSGYGMGHCLQVKDGTAVKATPANPLPQPPKDGDAIKKKFVDRAKRID 280 290 300 310 320 330 420 430 440 450 pF1KB4 TISRAAFPLAFLIFNIFYWITYKIIRHEDVHKK ::::::::::::::::::::::::::::::::: XP_016 TISRAAFPLAFLIFNIFYWITYKIIRHEDVHKK 340 350 360 >>XP_016884918 (OMIM: 305990) PREDICTED: glycine recepto (363 aa) initn: 2437 init1: 2437 opt: 2437 Z-score: 2974.1 bits: 559.2 E(85289): 6.4e-159 Smith-Waterman score: 2437; 100.0% identity (100.0% similar) in 363 aa overlap (90-452:1-363) 60 70 80 90 100 110 pF1KB4 ARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDL :::::::::::::::::::::::::::::: XP_016 MDYRVNIFLRQQWNDSRLAYSEYPDDSLDL 10 20 30 120 130 140 150 160 170 pF1KB4 DPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNF 40 50 60 70 80 90 180 190 200 210 220 230 pF1KB4 PMDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFILKEEKELGYCTKHYNTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PMDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFILKEEKELGYCTKHYNTG 100 110 120 130 140 150 240 250 260 270 280 290 pF1KB4 KFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTT 160 170 180 190 200 210 300 310 320 330 340 350 pF1KB4 QSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFLRLRRRQKRQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFLRLRRRQKRQN 220 230 240 250 260 270 360 370 380 390 400 410 pF1KB4 KEEDVTRESRFNFSGYGMGHCLQVKDGTAVKATPANPLPQPPKDGDAIKKKFVDRAKRID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KEEDVTRESRFNFSGYGMGHCLQVKDGTAVKATPANPLPQPPKDGDAIKKKFVDRAKRID 280 290 300 310 320 330 420 430 440 450 pF1KB4 TISRAAFPLAFLIFNIFYWITYKIIRHEDVHKK ::::::::::::::::::::::::::::::::: XP_016 TISRAAFPLAFLIFNIFYWITYKIIRHEDVHKK 340 350 360 >>NP_001165413 (OMIM: 305990) glycine receptor subunit a (363 aa) initn: 2437 init1: 2437 opt: 2437 Z-score: 2974.1 bits: 559.2 E(85289): 6.4e-159 Smith-Waterman score: 2437; 100.0% identity (100.0% similar) in 363 aa overlap (90-452:1-363) 60 70 80 90 100 110 pF1KB4 ARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDL :::::::::::::::::::::::::::::: NP_001 MDYRVNIFLRQQWNDSRLAYSEYPDDSLDL 10 20 30 120 130 140 150 160 170 pF1KB4 DPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNF 40 50 60 70 80 90 180 190 200 210 220 230 pF1KB4 PMDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFILKEEKELGYCTKHYNTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PMDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFILKEEKELGYCTKHYNTG 100 110 120 130 140 150 240 250 260 270 280 290 pF1KB4 KFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTT 160 170 180 190 200 210 300 310 320 330 340 350 pF1KB4 QSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFLRLRRRQKRQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFLRLRRRQKRQN 220 230 240 250 260 270 360 370 380 390 400 410 pF1KB4 KEEDVTRESRFNFSGYGMGHCLQVKDGTAVKATPANPLPQPPKDGDAIKKKFVDRAKRID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KEEDVTRESRFNFSGYGMGHCLQVKDGTAVKATPANPLPQPPKDGDAIKKKFVDRAKRID 280 290 300 310 320 330 420 430 440 450 pF1KB4 TISRAAFPLAFLIFNIFYWITYKIIRHEDVHKK ::::::::::::::::::::::::::::::::: NP_001 TISRAAFPLAFLIFNIFYWITYKIIRHEDVHKK 340 350 360 452 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 05:38:07 2016 done: Sat Nov 5 05:38:08 2016 Total Scan time: 7.130 Total Display time: 0.060 Function used was FASTA [36.3.4 Apr, 2011]