FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4108, 977 aa 1>>>pF1KB4108 977 - 977 aa - 977 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.9788+/-0.000477; mu= 18.4207+/- 0.030 mean_var=108.1878+/-21.085, 0's: 0 Z-trim(110.5): 133 B-trim: 360 in 1/55 Lambda= 0.123306 statistics sampled from 18737 (18870) to 18737 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.569), E-opt: 0.2 (0.221), width: 16 Scan time: 14.000 The best scores are: opt bits E(85289) NP_057263 (OMIM: 603651) short transient receptor ( 977) 6440 1157.9 0 NP_003297 (OMIM: 603651) short transient receptor ( 982) 6420 1154.4 0 NP_001129427 (OMIM: 603651) short transient recept ( 893) 5192 935.9 0 NP_001129429 (OMIM: 603651) short transient recept ( 836) 4868 878.2 0 NP_001129430 (OMIM: 603651) short transient recept ( 804) 4543 820.4 0 NP_036603 (OMIM: 300334) short transient receptor ( 973) 4171 754.3 7.1e-217 XP_016885263 (OMIM: 300334) PREDICTED: short trans ( 973) 4171 754.3 7.1e-217 NP_001129428 (OMIM: 603651) short transient recept ( 828) 4153 751.0 5.8e-216 XP_016876213 (OMIM: 603651) PREDICTED: short trans ( 557) 3660 663.2 1.1e-189 XP_016876212 (OMIM: 603651) PREDICTED: short trans ( 562) 3640 659.6 1.3e-188 XP_011533508 (OMIM: 603651) PREDICTED: short trans ( 562) 3640 659.6 1.3e-188 NP_001238774 (OMIM: 602343) short transient recept ( 793) 2284 418.5 6.9e-116 XP_016862610 (OMIM: 602343) PREDICTED: short trans ( 732) 2228 408.5 6.5e-113 XP_005247795 (OMIM: 602343) PREDICTED: short trans ( 695) 2086 383.2 2.5e-105 NP_003295 (OMIM: 602343) short transient receptor ( 759) 2019 371.3 1e-101 XP_016862611 (OMIM: 602343) PREDICTED: short trans ( 709) 2017 371.0 1.3e-101 XP_005247796 (OMIM: 602343) PREDICTED: short trans ( 661) 2002 368.3 7.6e-101 NP_003296 (OMIM: 602345,616410) short transient re ( 848) 803 155.1 1.5e-36 XP_016864068 (OMIM: 602345,616410) PREDICTED: shor ( 893) 803 155.1 1.5e-36 XP_011530520 (OMIM: 602345,616410) PREDICTED: shor ( 920) 803 155.1 1.6e-36 NP_001124170 (OMIM: 602345,616410) short transient ( 921) 803 155.1 1.6e-36 XP_016864067 (OMIM: 602345,616410) PREDICTED: shor ( 936) 803 155.1 1.6e-36 XP_011530519 (OMIM: 602345,616410) PREDICTED: shor ( 937) 803 155.1 1.6e-36 XP_016873711 (OMIM: 603652,603965) PREDICTED: shor ( 845) 778 150.6 3.2e-35 XP_011541270 (OMIM: 603652,603965) PREDICTED: shor ( 876) 778 150.6 3.3e-35 NP_004612 (OMIM: 603652,603965) short transient re ( 931) 778 150.7 3.4e-35 XP_016873710 (OMIM: 603652,603965) PREDICTED: shor ( 815) 498 100.8 3.1e-20 NP_002411 (OMIM: 603576,613216) transient receptor (1603) 263 59.2 2e-07 NP_001238953 (OMIM: 603576,613216) transient recep (1625) 263 59.3 2e-07 NP_001238949 (OMIM: 603576,613216) transient recep (1642) 263 59.3 2e-07 XP_016877844 (OMIM: 105500,605692) PREDICTED: tran (1826) 258 58.4 4e-07 XP_016877843 (OMIM: 105500,605692) PREDICTED: tran (1826) 258 58.4 4e-07 NP_001288141 (OMIM: 105500,605692) transient recep (1864) 258 58.4 4e-07 NP_060142 (OMIM: 105500,605692) transient receptor (1865) 258 58.4 4e-07 XP_016877842 (OMIM: 105500,605692) PREDICTED: tran (1873) 258 58.4 4.1e-07 XP_016877841 (OMIM: 105500,605692) PREDICTED: tran (1874) 258 58.4 4.1e-07 XP_005254543 (OMIM: 105500,605692) PREDICTED: tran (1885) 258 58.4 4.1e-07 XP_016877840 (OMIM: 105500,605692) PREDICTED: tran (1893) 258 58.4 4.1e-07 XP_016877839 (OMIM: 105500,605692) PREDICTED: tran (1894) 258 58.4 4.1e-07 XP_016870647 (OMIM: 608961) PREDICTED: transient r (1260) 244 55.8 1.7e-06 XP_016870649 (OMIM: 608961) PREDICTED: transient r (1172) 242 55.4 2.1e-06 XP_016870648 (OMIM: 608961) PREDICTED: transient r (1184) 242 55.4 2.1e-06 XP_016870645 (OMIM: 608961) PREDICTED: transient r (1290) 242 55.4 2.2e-06 XP_016870646 (OMIM: 608961) PREDICTED: transient r (1315) 242 55.4 2.2e-06 XP_011517349 (OMIM: 608961) PREDICTED: transient r (1325) 242 55.4 2.3e-06 XP_016870642 (OMIM: 608961) PREDICTED: transient r (1327) 242 55.4 2.3e-06 XP_016870644 (OMIM: 608961) PREDICTED: transient r (1337) 242 55.4 2.3e-06 XP_016870640 (OMIM: 608961) PREDICTED: transient r (1339) 242 55.4 2.3e-06 XP_016870639 (OMIM: 608961) PREDICTED: transient r (1352) 242 55.4 2.3e-06 XP_016870643 (OMIM: 608961) PREDICTED: transient r (1352) 242 55.4 2.3e-06 >>NP_057263 (OMIM: 603651) short transient receptor pote (977 aa) initn: 6440 init1: 6440 opt: 6440 Z-score: 6196.0 bits: 1157.9 E(85289): 0 Smith-Waterman score: 6440; 100.0% identity (100.0% similar) in 977 aa overlap (1-977:1-977) 10 20 30 40 50 60 pF1KB4 MAQFYYKRNVNAPYRDRIPLRIVRAESELSPSEKAYLNAVEKGDYASVKKSLEEAEIYFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 MAQFYYKRNVNAPYRDRIPLRIVRAESELSPSEKAYLNAVEKGDYASVKKSLEEAEIYFK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 ININCIDPLGRTALLIAIENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 ININCIDPLGRTALLIAIENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 PSGEKQVPPILLDKQFSEFTPDITPIILAAHTNNYEIIKLLVQKGVSVPRPHEVRCNCVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 PSGEKQVPPILLDKQFSEFTPDITPIILAAHTNNYEIIKLLVQKGVSVPRPHEVRCNCVE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 CVSSSDVDSLRHSRSRLNIYKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 CVSSSDVDSLRHSRSRLNIYKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKSE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 YEELSRQCKQFAKDLLDQTRSSRELEIILNYRDDNSLIEEQSGNDLARLKLAIKYRQKEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 YEELSRQCKQFAKDLLDQTRSSRELEIILNYRDDNSLIEEQSGNDLARLKLAIKYRQKEF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 VAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLGLFIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 VAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLGLFIR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 KPFIKFICHTASYLTFLFLLLLASQHIDRSDLNRQGPPPTIVEWMILPWVLGFIWGEIKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 KPFIKFICHTASYLTFLFLLLLASQHIDRSDLNRQGPPPTIVEWMILPWVLGFIWGEIKQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB4 MWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYSALNPRESWDMWHPTLVAEAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 MWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYSALNPRESWDMWHPTLVAEAL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB4 FAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 FAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFY 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB4 YEETKGLTCKGIRCEKQNNAFSTLFETLQSLFWSIFGLINLYVTNVKAQHEFTEFVGATM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 YEETKGLTCKGIRCEKQNNAFSTLFETLQSLFWSIFGLINLYVTNVKAQHEFTEFVGATM 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB4 FGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFEEGGTLPTPFNVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 FGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFEEGGTLPTPFNVI 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB4 PSPKSLWYLIKWIWTHLCKKKMRRKPESFGTIGRRAADNLRRHHQYQEVMRNLVKRYVAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 PSPKSLWYLIKWIWTHLCKKKMRRKPESFGTIGRRAADNLRRHHQYQEVMRNLVKRYVAA 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB4 MIRDAKTEEGLTEENFKELKQDISSFRFEVLGLLRGSKLSTIQSANASKESSNSADSDEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 MIRDAKTEEGLTEENFKELKQDISSFRFEVLGLLRGSKLSTIQSANASKESSNSADSDEK 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB4 SDSEGNSKDKKKNFSLFDLTTLIHPRSAAIASERHNISNGSALVVQEPPREKQRKVNFVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 SDSEGNSKDKKKNFSLFDLTTLIHPRSAAIASERHNISNGSALVVQEPPREKQRKVNFVT 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB4 DIKNFGLFHRRSKQNAAEQNANQIFSVSEEVARQQAAGPLERNIQLESRGLASRGDLSIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 DIKNFGLFHRRSKQNAAEQNANQIFSVSEEVARQQAAGPLERNIQLESRGLASRGDLSIP 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB4 GLSEQCVLVDHRERNTDTLGLQVGKRVCPFKSEKVVVEDTVPIIPKEKHAKEEDSSIDYD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 GLSEQCVLVDHRERNTDTLGLQVGKRVCPFKSEKVVVEDTVPIIPKEKHAKEEDSSIDYD 910 920 930 940 950 960 970 pF1KB4 LNLPDTVTHEDYVTTRL ::::::::::::::::: NP_057 LNLPDTVTHEDYVTTRL 970 >>NP_003297 (OMIM: 603651) short transient receptor pote (982 aa) initn: 4636 init1: 4636 opt: 6420 Z-score: 6176.7 bits: 1154.4 E(85289): 0 Smith-Waterman score: 6420; 99.5% identity (99.5% similar) in 982 aa overlap (1-977:1-982) 10 20 30 40 50 60 pF1KB4 MAQFYYKRNVNAPYRDRIPLRIVRAESELSPSEKAYLNAVEKGDYASVKKSLEEAEIYFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 MAQFYYKRNVNAPYRDRIPLRIVRAESELSPSEKAYLNAVEKGDYASVKKSLEEAEIYFK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 ININCIDPLGRTALLIAIENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 ININCIDPLGRTALLIAIENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 PSGEKQVPPILLDKQFSEFTPDITPIILAAHTNNYEIIKLLVQKGVSVPRPHEVRCNCVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 PSGEKQVPPILLDKQFSEFTPDITPIILAAHTNNYEIIKLLVQKGVSVPRPHEVRCNCVE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 CVSSSDVDSLRHSRSRLNIYKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 CVSSSDVDSLRHSRSRLNIYKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKSE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 YEELSRQCKQFAKDLLDQTRSSRELEIILNYRDDNSLIEEQSGNDLARLKLAIKYRQKEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 YEELSRQCKQFAKDLLDQTRSSRELEIILNYRDDNSLIEEQSGNDLARLKLAIKYRQKEF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 VAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLGLFIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 VAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLGLFIR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 KPFIKFICHTASYLTFLFLLLLASQHIDRSDLNRQGPPPTIVEWMILPWVLGFIWGEIKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 KPFIKFICHTASYLTFLFLLLLASQHIDRSDLNRQGPPPTIVEWMILPWVLGFIWGEIKQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB4 MWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYSALNPRESWDMWHPTLVAEAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 MWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYSALNPRESWDMWHPTLVAEAL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB4 FAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 FAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFY 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB4 YEETKGLTCKGIRCEKQNNAFSTLFETLQSLFWSIFGLINLYVTNVKAQHEFTEFVGATM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 YEETKGLTCKGIRCEKQNNAFSTLFETLQSLFWSIFGLINLYVTNVKAQHEFTEFVGATM 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB4 FGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFEEGGTLPTPFNVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 FGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFEEGGTLPTPFNVI 610 620 630 640 650 660 670 680 690 700 710 pF1KB4 PSPKSLWYLIKWIWTHLCKKKMRRKPESFGTIG-----RRAADNLRRHHQYQEVMRNLVK ::::::::::::::::::::::::::::::::: :::::::::::::::::::::: NP_003 PSPKSLWYLIKWIWTHLCKKKMRRKPESFGTIGVRTQHRRAADNLRRHHQYQEVMRNLVK 670 680 690 700 710 720 720 730 740 750 760 770 pF1KB4 RYVAAMIRDAKTEEGLTEENFKELKQDISSFRFEVLGLLRGSKLSTIQSANASKESSNSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 RYVAAMIRDAKTEEGLTEENFKELKQDISSFRFEVLGLLRGSKLSTIQSANASKESSNSA 730 740 750 760 770 780 780 790 800 810 820 830 pF1KB4 DSDEKSDSEGNSKDKKKNFSLFDLTTLIHPRSAAIASERHNISNGSALVVQEPPREKQRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 DSDEKSDSEGNSKDKKKNFSLFDLTTLIHPRSAAIASERHNISNGSALVVQEPPREKQRK 790 800 810 820 830 840 840 850 860 870 880 890 pF1KB4 VNFVTDIKNFGLFHRRSKQNAAEQNANQIFSVSEEVARQQAAGPLERNIQLESRGLASRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 VNFVTDIKNFGLFHRRSKQNAAEQNANQIFSVSEEVARQQAAGPLERNIQLESRGLASRG 850 860 870 880 890 900 900 910 920 930 940 950 pF1KB4 DLSIPGLSEQCVLVDHRERNTDTLGLQVGKRVCPFKSEKVVVEDTVPIIPKEKHAKEEDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 DLSIPGLSEQCVLVDHRERNTDTLGLQVGKRVCPFKSEKVVVEDTVPIIPKEKHAKEEDS 910 920 930 940 950 960 960 970 pF1KB4 SIDYDLNLPDTVTHEDYVTTRL :::::::::::::::::::::: NP_003 SIDYDLNLPDTVTHEDYVTTRL 970 980 >>NP_001129427 (OMIM: 603651) short transient receptor p (893 aa) initn: 5192 init1: 5192 opt: 5192 Z-score: 4996.7 bits: 935.9 E(85289): 0 Smith-Waterman score: 5724; 91.4% identity (91.4% similar) in 977 aa overlap (1-977:1-893) 10 20 30 40 50 60 pF1KB4 MAQFYYKRNVNAPYRDRIPLRIVRAESELSPSEKAYLNAVEKGDYASVKKSLEEAEIYFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAQFYYKRNVNAPYRDRIPLRIVRAESELSPSEKAYLNAVEKGDYASVKKSLEEAEIYFK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 ININCIDPLGRTALLIAIENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ININCIDPLGRTALLIAIENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 PSGEKQVPPILLDKQFSEFTPDITPIILAAHTNNYEIIKLLVQKGVSVPRPHEVRCNCVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PSGEKQVPPILLDKQFSEFTPDITPIILAAHTNNYEIIKLLVQKGVSVPRPHEVRCNCVE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 CVSSSDVDSLRHSRSRLNIYKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CVSSSDVDSLRHSRSRLNIYKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKSE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 YEELSRQCKQFAKDLLDQTRSSRELEIILNYRDDNSLIEEQSGNDLARLKLAIKYRQKEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YEELSRQCKQFAKDLLDQTRSSRELEIILNYRDDNSLIEEQSGNDLARLKLAIKYRQKEF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 VAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLGLFIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLGLFIR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 KPFIKFICHTASYLTFLFLLLLASQHIDRSDLNRQGPPPTIVEWMILPWVLGFIWGEIKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KPFIKFICHTASYLTFLFLLLLASQHIDRSDLNRQGPPPTIVEWMILPWVLGFIWGEIKQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB4 MWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYSALNPRESWDMWHPTLVAEAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYSALNPRESWDMWHPTLVAEAL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB4 FAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFY 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB4 YEETKGLTCKGIRCEKQNNAFSTLFETLQSLFWSIFGLINLYVTNVKAQHEFTEFVGATM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YEETKGLTCKGIRCEKQNNAFSTLFETLQSLFWSIFGLINLYVTNVKAQHEFTEFVGATM 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB4 FGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFEEGGTLPTPFNVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFEEGGTLPTPFNVI 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB4 PSPKSLWYLIKWIWTHLCKKKMRRKPESFGTIGRRAADNLRRHHQYQEVMRNLVKRYVAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PSPKSLWYLIKWIWTHLCKKKMRRKPESFGTIGRRAADNLRRHHQYQEVMRNLVKRYVAA 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB4 MIRDAKTEEGLTEENFKELKQDISSFRFEVLGLLRGSKLSTIQSANASKESSNSADSDEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MIRDAKTEEGLTEENFKELKQDISSFRFEVLGLLRGSKLSTIQSANASKESSNSADSDEK 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB4 SDSEGNSKDKKKNFSLFDLTTLIHPRSAAIASERHNISNGSALVVQEPPREKQRKVNFVT :::: NP_001 SDSE-------------------------------------------------------- 850 860 870 880 890 900 pF1KB4 DIKNFGLFHRRSKQNAAEQNANQIFSVSEEVARQQAAGPLERNIQLESRGLASRGDLSIP :::::::::::::::::::::::::::::::: NP_001 ----------------------------EEVARQQAAGPLERNIQLESRGLASRGDLSIP 790 800 810 910 920 930 940 950 960 pF1KB4 GLSEQCVLVDHRERNTDTLGLQVGKRVCPFKSEKVVVEDTVPIIPKEKHAKEEDSSIDYD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GLSEQCVLVDHRERNTDTLGLQVGKRVCPFKSEKVVVEDTVPIIPKEKHAKEEDSSIDYD 820 830 840 850 860 870 970 pF1KB4 LNLPDTVTHEDYVTTRL ::::::::::::::::: NP_001 LNLPDTVTHEDYVTTRL 880 890 >>NP_001129429 (OMIM: 603651) short transient receptor p (836 aa) initn: 4861 init1: 4861 opt: 4868 Z-score: 4685.5 bits: 878.2 E(85289): 0 Smith-Waterman score: 5267; 85.6% identity (85.6% similar) in 977 aa overlap (1-977:1-836) 10 20 30 40 50 60 pF1KB4 MAQFYYKRNVNAPYRDRIPLRIVRAESELSPSEKAYLNAVEKGDYASVKKSLEEAEIYFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAQFYYKRNVNAPYRDRIPLRIVRAESELSPSEKAYLNAVEKGDYASVKKSLEEAEIYFK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 ININCIDPLGRTALLIAIENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ININCIDPLGRTALLIAIENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 PSGEKQVPPILLDKQFSEFTPDITPIILAAHTNNYEIIKLLVQKGVSVPRPHEVRCNCVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PSGEKQVPPILLDKQFSEFTPDITPIILAAHTNNYEIIKLLVQKGVSVPRPHEVRCNCVE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 CVSSSDVDSLRHSRSRLNIYKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CVSSSDVDSLRHSRSRLNIYKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKSE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 YEELSRQCKQFAKDLLDQTRSSRELEIILNYRDDNSLIEEQSGNDLARLKLAIKYRQKEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YEELSRQCKQFAKDLLDQTRSSRELEIILNYRDDNSLIEEQSGNDLARLKLAIKYRQKEF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 VAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLGLFIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLGLFIR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 KPFIKFICHTASYLTFLFLLLLASQHIDRSDLNRQGPPPTIVEWMILPWVLGFIWGEIKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KPFIKFICHTASYLTFLFLLLLASQHIDRSDLNRQGPPPTIVEWMILPWVLGFIWGEIKQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB4 MWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYSALNPRESWDMWHPTLVAEAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYSALNPRESWDMWHPTLVAEAL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB4 FAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFY 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB4 YEETKGLTCKGIRCEKQNNAFSTLFETLQSLFWSIFGLINLYVTNVKAQHEFTEFVGATM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YEETKGLTCKGIRCEKQNNAFSTLFETLQSLFWSIFGLINLYVTNVKAQHEFTEFVGATM 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB4 FGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFEEGGTLPTPFNVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFEEGGTLPTPFNVI 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB4 PSPKSLWYLIKWIWTHLCKKKMRRKPESFGTIGRRAADNLRRHHQYQEVMRNLVKRYVAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PSPKSLWYLIKWIWTHLCKKKMRRKPESFGTIGRRAADNLRRHHQYQEVMRNLVKRYVAA 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB4 MIRDAKTEEGLTEENFKELKQDISSFRFEVLGLLRGSKLSTIQSANASKESSNSADSDEK ::::::::: NP_001 MIRDAKTEE--------------------------------------------------- 790 800 810 820 830 840 pF1KB4 SDSEGNSKDKKKNFSLFDLTTLIHPRSAAIASERHNISNGSALVVQEPPREKQRKVNFVT NP_001 ------------------------------------------------------------ 850 860 870 880 890 900 pF1KB4 DIKNFGLFHRRSKQNAAEQNANQIFSVSEEVARQQAAGPLERNIQLESRGLASRGDLSIP :::::::::::::::::::::::::::::: NP_001 ------------------------------VARQQAAGPLERNIQLESRGLASRGDLSIP 730 740 750 910 920 930 940 950 960 pF1KB4 GLSEQCVLVDHRERNTDTLGLQVGKRVCPFKSEKVVVEDTVPIIPKEKHAKEEDSSIDYD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GLSEQCVLVDHRERNTDTLGLQVGKRVCPFKSEKVVVEDTVPIIPKEKHAKEEDSSIDYD 760 770 780 790 800 810 970 pF1KB4 LNLPDTVTHEDYVTTRL ::::::::::::::::: NP_001 LNLPDTVTHEDYVTTRL 820 830 >>NP_001129430 (OMIM: 603651) short transient receptor p (804 aa) initn: 4543 init1: 4543 opt: 4543 Z-score: 4373.3 bits: 820.4 E(85289): 0 Smith-Waterman score: 4969; 82.3% identity (82.3% similar) in 977 aa overlap (1-977:1-804) 10 20 30 40 50 60 pF1KB4 MAQFYYKRNVNAPYRDRIPLRIVRAESELSPSEKAYLNAVEKGDYASVKKSLEEAEIYFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAQFYYKRNVNAPYRDRIPLRIVRAESELSPSEKAYLNAVEKGDYASVKKSLEEAEIYFK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 ININCIDPLGRTALLIAIENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ININCIDPLGRTALLIAIENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 PSGEKQVPPILLDKQFSEFTPDITPIILAAHTNNYEIIKLLVQKGVSVPRPHEVRCNCVE :::::: NP_001 PSGEKQ------------------------------------------------------ 190 200 210 220 230 240 pF1KB4 CVSSSDVDSLRHSRSRLNIYKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKSE NP_001 ------------------------------------------------------------ 250 260 270 280 290 300 pF1KB4 YEELSRQCKQFAKDLLDQTRSSRELEIILNYRDDNSLIEEQSGNDLARLKLAIKYRQKEF : NP_001 -----------------------------------------------------------F 310 320 330 340 350 360 pF1KB4 VAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLGLFIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLGLFIR 130 140 150 160 170 180 370 380 390 400 410 420 pF1KB4 KPFIKFICHTASYLTFLFLLLLASQHIDRSDLNRQGPPPTIVEWMILPWVLGFIWGEIKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KPFIKFICHTASYLTFLFLLLLASQHIDRSDLNRQGPPPTIVEWMILPWVLGFIWGEIKQ 190 200 210 220 230 240 430 440 450 460 470 480 pF1KB4 MWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYSALNPRESWDMWHPTLVAEAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYSALNPRESWDMWHPTLVAEAL 250 260 270 280 290 300 490 500 510 520 530 540 pF1KB4 FAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFY 310 320 330 340 350 360 550 560 570 580 590 600 pF1KB4 YEETKGLTCKGIRCEKQNNAFSTLFETLQSLFWSIFGLINLYVTNVKAQHEFTEFVGATM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YEETKGLTCKGIRCEKQNNAFSTLFETLQSLFWSIFGLINLYVTNVKAQHEFTEFVGATM 370 380 390 400 410 420 610 620 630 640 650 660 pF1KB4 FGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFEEGGTLPTPFNVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFEEGGTLPTPFNVI 430 440 450 460 470 480 670 680 690 700 710 720 pF1KB4 PSPKSLWYLIKWIWTHLCKKKMRRKPESFGTIGRRAADNLRRHHQYQEVMRNLVKRYVAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PSPKSLWYLIKWIWTHLCKKKMRRKPESFGTIGRRAADNLRRHHQYQEVMRNLVKRYVAA 490 500 510 520 530 540 730 740 750 760 770 780 pF1KB4 MIRDAKTEEGLTEENFKELKQDISSFRFEVLGLLRGSKLSTIQSANASKESSNSADSDEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MIRDAKTEEGLTEENFKELKQDISSFRFEVLGLLRGSKLSTIQSANASKESSNSADSDEK 550 560 570 580 590 600 790 800 810 820 830 840 pF1KB4 SDSEGNSKDKKKNFSLFDLTTLIHPRSAAIASERHNISNGSALVVQEPPREKQRKVNFVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SDSEGNSKDKKKNFSLFDLTTLIHPRSAAIASERHNISNGSALVVQEPPREKQRKVNFVT 610 620 630 640 650 660 850 860 870 880 890 900 pF1KB4 DIKNFGLFHRRSKQNAAEQNANQIFSVSEEVARQQAAGPLERNIQLESRGLASRGDLSIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DIKNFGLFHRRSKQNAAEQNANQIFSVSEEVARQQAAGPLERNIQLESRGLASRGDLSIP 670 680 690 700 710 720 910 920 930 940 950 960 pF1KB4 GLSEQCVLVDHRERNTDTLGLQVGKRVCPFKSEKVVVEDTVPIIPKEKHAKEEDSSIDYD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GLSEQCVLVDHRERNTDTLGLQVGKRVCPFKSEKVVVEDTVPIIPKEKHAKEEDSSIDYD 730 740 750 760 770 780 970 pF1KB4 LNLPDTVTHEDYVTTRL ::::::::::::::::: NP_001 LNLPDTVTHEDYVTTRL 790 800 >>NP_036603 (OMIM: 300334) short transient receptor pote (973 aa) initn: 2656 init1: 1561 opt: 4171 Z-score: 4014.6 bits: 754.3 E(85289): 7.1e-217 Smith-Waterman score: 4171; 69.9% identity (87.5% similar) in 913 aa overlap (1-904:1-903) 10 20 30 40 50 60 pF1KB4 MAQFYYKRNVNAPYRDRIPLRIVRAESELSPSEKAYLNAVEKGDYASVKKSLEEAEIYFK :::.:::. .::::::::.:::::.::: :::.::::::::::.::..:.:::::.. NP_036 MAQLYYKKVNYSPYRDRIPLQIVRAETELSAEEKAFLNAVEKGDYATVKQALQEAEIYYN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 ININCIDPLGRTALLIAIENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKK .::::.:::::.::::::::::::..::::. .::::::::.::::::::::::::.... NP_036 VNINCMDPLGRSALLIAIENENLEIMELLLNHSVYVGDALLYAIRKEVVGAVELLLSYRR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 PSGEKQVPPILLDKQFSEFTPDITPIILAAHTNNYEIIKLLVQKGVSVPRPHEVRCNCVE :::::::: ...: ::::::::::::.::::::::::::::::: :..::::..:::::: NP_036 PSGEKQVPTLMMDTQFSEFTPDITPIMLAAHTNNYEIIKLLVQKRVTIPRPHQIRCNCVE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 CVSSSDVDSLRHSRSRLNIYKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKSE :::::.::::::::::::::::::::::::::::::.::::.:.:::.::::::::::.: NP_036 CVSSSEVDSLRHSRSRLNIYKALASPSLIALSSEDPILTAFRLGWELKELSKVENEFKAE 190 200 210 220 230 240 250 260 270 280 290 pF1KB4 YEELSRQCKQFAKDLLDQTRSSRELEIILNYRDDNSL-IEEQSGNDLARLKLAIKYRQKE :::::.::: ::::::::.:::::::::::.:::.: .. :. .:::.::.::::.::: NP_036 YEELSQQCKLFAKDLLDQARSSRELEIILNHRDDHSEELDPQKYHDLAKLKVAIKYHQKE 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB4 FVAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLGLFI ::::::::::::. ::: ::::::.::.::..::. ::.:::..:. :::.:.: ::::: NP_036 FVAQPNCQQLLATLWYDGFPGWRRKHWVVKLLTCMTIGFLFPMLSIAYLISPRSNLGLFI 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB4 RKPFIKFICHTASYLTFLFLLLLASQHIDRSDLNRQGPPPTIVEWMILPWVLGFIWGEIK .::::::::::::::::::.:::::::: :.::. ::::::.:::::::::::::::::: NP_036 KKPFIKFICHTASYLTFLFMLLLASQHIVRTDLHVQGPPPTVVEWMILPWVLGFIWGEIK 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB4 QMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYSALNPRESWDMWHPTLVAEA .:::::. .:::::::::::.:::::::::::::::.:::.. ::: :.::::::.::: NP_036 EMWDGGFTEYIHDWWNLMDFAMNSLYLATISLKIVAYVKYNGSRPREEWEMWHPTLIAEA 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB4 LFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYF ::::.::.:::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 LFAISNILSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYF 490 500 510 520 530 540 540 550 560 570 580 590 pF1KB4 YYEETKGL----TCKGIRCEKQNNAFSTLFETLQSLFWSIFGLINLYVTNVKAQHEFTEF ::: :... .::::::::::::::::::::::::::.:::.:::::::::.:::::: NP_036 YYE-TRAIDEPNNCKGIRCEKQNNAFSTLFETLQSLFWSVFGLLNLYVTNVKARHEFTEF 550 560 570 580 590 600 610 620 630 640 650 pF1KB4 VGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFEEGGTLPT ::::::::::::::::::::::::::::::::::::::::::::::::::::.:::::: NP_036 VGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFDEGGTLPP 600 610 620 630 640 650 660 670 680 690 700 710 pF1KB4 PFNVIPSPKSLWYLIKWIWTHLCKKK---MRRKPESFGTIGRRAADNLRRHHQYQEVMRN :::.::::::. :: .:. . .: :. ::. ... .. .: ::.: ....::::.:: NP_036 PFNIIPSPKSFLYLGNWFNNTFCPKRDPDGRRRRRNLRSFTERNADSLIQNQHYQEVIRN 660 670 680 690 700 710 720 730 740 750 760 770 pF1KB4 LVKRYVAAMIRDAKTEEGLTEENFKELKQDISSFRFEVLGLLRGSKLSTIQSANASKESS :::::::::::..::.:::::::::::::::::::.::: :: . : . . : :. NP_036 LVKRYVAAMIRNSKTHEGLTEENFKELKQDISSFRYEVLDLLGNRK----HPRSFSTSST 720 730 740 750 760 770 780 790 800 810 820 830 pF1KB4 NSADSDEKSDSEGNSKDKKKNFSLFDLTTLIHPRSAAIASERHNISNGSALVVQEPPREK . .. :...:. :... :.:. : :.: . . . :.:. . :. NP_036 ELSQRDDNNDGSGGARAKSKSVS-FNLGCKKKTCHGPPLIRTMPRSSGAQ---GKSKAES 780 790 800 810 820 830 840 850 860 870 880 890 pF1KB4 QRKVNFV-TDIKNFGLFHRRSKQNAAEQNANQIFSVSEEVARQQAAGPLERNIQLESRGL . : .:. ..:..::. . . . .: ... ....:. ...:. : :.: .: NP_036 SSKRSFMGPSLKKLGLLFSKFNGHMSEPSSEPMYTISDGIVQQHCMWQDIRYSQME-KGK 840 850 860 870 880 890 900 910 920 930 940 950 pF1KB4 ASRGDLSIPGLSEQCVLVDHRERNTDTLGLQVGKRVCPFKSEKVVVEDTVPIIPKEKHAK : . : .::: NP_036 AEACSQSEINLSEVELGEVQGAAQSSECPLACSSSLHCASSICSSNSKLLDSSEDVFETW 900 910 920 930 940 950 >>XP_016885263 (OMIM: 300334) PREDICTED: short transient (973 aa) initn: 2656 init1: 1561 opt: 4171 Z-score: 4014.6 bits: 754.3 E(85289): 7.1e-217 Smith-Waterman score: 4171; 69.9% identity (87.5% similar) in 913 aa overlap (1-904:1-903) 10 20 30 40 50 60 pF1KB4 MAQFYYKRNVNAPYRDRIPLRIVRAESELSPSEKAYLNAVEKGDYASVKKSLEEAEIYFK :::.:::. .::::::::.:::::.::: :::.::::::::::.::..:.:::::.. XP_016 MAQLYYKKVNYSPYRDRIPLQIVRAETELSAEEKAFLNAVEKGDYATVKQALQEAEIYYN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 ININCIDPLGRTALLIAIENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKK .::::.:::::.::::::::::::..::::. .::::::::.::::::::::::::.... XP_016 VNINCMDPLGRSALLIAIENENLEIMELLLNHSVYVGDALLYAIRKEVVGAVELLLSYRR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 PSGEKQVPPILLDKQFSEFTPDITPIILAAHTNNYEIIKLLVQKGVSVPRPHEVRCNCVE :::::::: ...: ::::::::::::.::::::::::::::::: :..::::..:::::: XP_016 PSGEKQVPTLMMDTQFSEFTPDITPIMLAAHTNNYEIIKLLVQKRVTIPRPHQIRCNCVE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 CVSSSDVDSLRHSRSRLNIYKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKSE :::::.::::::::::::::::::::::::::::::.::::.:.:::.::::::::::.: XP_016 CVSSSEVDSLRHSRSRLNIYKALASPSLIALSSEDPILTAFRLGWELKELSKVENEFKAE 190 200 210 220 230 240 250 260 270 280 290 pF1KB4 YEELSRQCKQFAKDLLDQTRSSRELEIILNYRDDNSL-IEEQSGNDLARLKLAIKYRQKE :::::.::: ::::::::.:::::::::::.:::.: .. :. .:::.::.::::.::: XP_016 YEELSQQCKLFAKDLLDQARSSRELEIILNHRDDHSEELDPQKYHDLAKLKVAIKYHQKE 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB4 FVAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLGLFI ::::::::::::. ::: ::::::.::.::..::. ::.:::..:. :::.:.: ::::: XP_016 FVAQPNCQQLLATLWYDGFPGWRRKHWVVKLLTCMTIGFLFPMLSIAYLISPRSNLGLFI 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB4 RKPFIKFICHTASYLTFLFLLLLASQHIDRSDLNRQGPPPTIVEWMILPWVLGFIWGEIK .::::::::::::::::::.:::::::: :.::. ::::::.:::::::::::::::::: XP_016 KKPFIKFICHTASYLTFLFMLLLASQHIVRTDLHVQGPPPTVVEWMILPWVLGFIWGEIK 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB4 QMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYSALNPRESWDMWHPTLVAEA .:::::. .:::::::::::.:::::::::::::::.:::.. ::: :.::::::.::: XP_016 EMWDGGFTEYIHDWWNLMDFAMNSLYLATISLKIVAYVKYNGSRPREEWEMWHPTLIAEA 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB4 LFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYF ::::.::.:::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LFAISNILSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYF 490 500 510 520 530 540 540 550 560 570 580 590 pF1KB4 YYEETKGL----TCKGIRCEKQNNAFSTLFETLQSLFWSIFGLINLYVTNVKAQHEFTEF ::: :... .::::::::::::::::::::::::::.:::.:::::::::.:::::: XP_016 YYE-TRAIDEPNNCKGIRCEKQNNAFSTLFETLQSLFWSVFGLLNLYVTNVKARHEFTEF 550 560 570 580 590 600 610 620 630 640 650 pF1KB4 VGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFEEGGTLPT ::::::::::::::::::::::::::::::::::::::::::::::::::::.:::::: XP_016 VGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFDEGGTLPP 600 610 620 630 640 650 660 670 680 690 700 710 pF1KB4 PFNVIPSPKSLWYLIKWIWTHLCKKK---MRRKPESFGTIGRRAADNLRRHHQYQEVMRN :::.::::::. :: .:. . .: :. ::. ... .. .: ::.: ....::::.:: XP_016 PFNIIPSPKSFLYLGNWFNNTFCPKRDPDGRRRRRNLRSFTERNADSLIQNQHYQEVIRN 660 670 680 690 700 710 720 730 740 750 760 770 pF1KB4 LVKRYVAAMIRDAKTEEGLTEENFKELKQDISSFRFEVLGLLRGSKLSTIQSANASKESS :::::::::::..::.:::::::::::::::::::.::: :: . : . . : :. XP_016 LVKRYVAAMIRNSKTHEGLTEENFKELKQDISSFRYEVLDLLGNRK----HPRSFSTSST 720 730 740 750 760 770 780 790 800 810 820 830 pF1KB4 NSADSDEKSDSEGNSKDKKKNFSLFDLTTLIHPRSAAIASERHNISNGSALVVQEPPREK . .. :...:. :... :.:. : :.: . . . :.:. . :. XP_016 ELSQRDDNNDGSGGARAKSKSVS-FNLGCKKKTCHGPPLIRTMPRSSGAQ---GKSKAES 780 790 800 810 820 830 840 850 860 870 880 890 pF1KB4 QRKVNFV-TDIKNFGLFHRRSKQNAAEQNANQIFSVSEEVARQQAAGPLERNIQLESRGL . : .:. ..:..::. . . . .: ... ....:. ...:. : :.: .: XP_016 SSKRSFMGPSLKKLGLLFSKFNGHMSEPSSEPMYTISDGIVQQHCMWQDIRYSQME-KGK 840 850 860 870 880 890 900 910 920 930 940 950 pF1KB4 ASRGDLSIPGLSEQCVLVDHRERNTDTLGLQVGKRVCPFKSEKVVVEDTVPIIPKEKHAK : . : .::: XP_016 AEACSQSEINLSEVELGEVQGAAQSSECPLACSSSLHCASSICSSNSKLLDSSEDVFETW 900 910 920 930 940 950 >>NP_001129428 (OMIM: 603651) short transient receptor p (828 aa) initn: 4859 init1: 4153 opt: 4153 Z-score: 3998.2 bits: 751.0 E(85289): 5.8e-216 Smith-Waterman score: 5106; 84.7% identity (84.7% similar) in 977 aa overlap (1-977:1-828) 10 20 30 40 50 60 pF1KB4 MAQFYYKRNVNAPYRDRIPLRIVRAESELSPSEKAYLNAVEKGDYASVKKSLEEAEIYFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAQFYYKRNVNAPYRDRIPLRIVRAESELSPSEKAYLNAVEKGDYASVKKSLEEAEIYFK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 ININCIDPLGRTALLIAIENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ININCIDPLGRTALLIAIENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 PSGEKQVPPILLDKQFSEFTPDITPIILAAHTNNYEIIKLLVQKGVSVPRPHEVRCNCVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PSGEKQVPPILLDKQFSEFTPDITPIILAAHTNNYEIIKLLVQKGVSVPRPHEVRCNCVE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 CVSSSDVDSLRHSRSRLNIYKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CVSSSDVDSLRHSRSRLNIYKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKSE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 YEELSRQCKQFAKDLLDQTRSSRELEIILNYRDDNSLIEEQSGNDLARLKLAIKYRQKEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YEELSRQCKQFAKDLLDQTRSSRELEIILNYRDDNSLIEEQSGNDLARLKLAIKYRQKEF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 VAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLGLFIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLGLFIR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 KPFIKFICHTASYLTFLFLLLLASQHIDRSDLNRQGPPPTIVEWMILPWVLGFIWGEIKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KPFIKFICHTASYLTFLFLLLLASQHIDRSDLNRQGPPPTIVEWMILPWVLGFIWGEIKQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB4 MWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYSALNPRESWDMWHPTLVAEAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYSALNPRESWDMWHPTLVAEAL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB4 FAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFY 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB4 YEETKGLTCKGIRCEKQNNAFSTLFETLQSLFWSIFGLINLYVTNVKAQHEFTEFVGATM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YEETKGLTCKGIRCEKQNNAFSTLFETLQSLFWSIFGLINLYVTNVKAQHEFTEFVGATM 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB4 FGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFEEGGTLPTPFNVI :::::::::::::::::::::::::::: NP_001 FGTYNVISLVVLLNMLIAMMNNSYQLIA-------------------------------- 610 620 670 680 690 700 710 720 pF1KB4 PSPKSLWYLIKWIWTHLCKKKMRRKPESFGTIGRRAADNLRRHHQYQEVMRNLVKRYVAA ::::::::::::::::::::::::::: NP_001 ---------------------------------RRAADNLRRHHQYQEVMRNLVKRYVAA 630 640 650 730 740 750 760 770 780 pF1KB4 MIRDAKTEEGLTEENFKELKQDISSFRFEVLGLLRGSKLSTIQSANASKESSNSADSDEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MIRDAKTEEGLTEENFKELKQDISSFRFEVLGLLRGSKLSTIQSANASKESSNSADSDEK 660 670 680 690 700 710 790 800 810 820 830 840 pF1KB4 SDSEGNSKDKKKNFSLFDLTTLIHPRSAAIASERHNISNGSALVVQEPPREKQRKVNFVT :::: NP_001 SDSE-------------------------------------------------------- 850 860 870 880 890 900 pF1KB4 DIKNFGLFHRRSKQNAAEQNANQIFSVSEEVARQQAAGPLERNIQLESRGLASRGDLSIP :::::::::::::::::::::::::::::::: NP_001 ----------------------------EEVARQQAAGPLERNIQLESRGLASRGDLSIP 720 730 740 750 910 920 930 940 950 960 pF1KB4 GLSEQCVLVDHRERNTDTLGLQVGKRVCPFKSEKVVVEDTVPIIPKEKHAKEEDSSIDYD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GLSEQCVLVDHRERNTDTLGLQVGKRVCPFKSEKVVVEDTVPIIPKEKHAKEEDSSIDYD 760 770 780 790 800 810 970 pF1KB4 LNLPDTVTHEDYVTTRL ::::::::::::::::: NP_001 LNLPDTVTHEDYVTTRL 820 >>XP_016876213 (OMIM: 603651) PREDICTED: short transient (557 aa) initn: 3660 init1: 3660 opt: 3660 Z-score: 3526.5 bits: 663.2 E(85289): 1.1e-189 Smith-Waterman score: 3660; 100.0% identity (100.0% similar) in 557 aa overlap (421-977:1-557) 400 410 420 430 440 450 pF1KB4 DLNRQGPPPTIVEWMILPWVLGFIWGEIKQMWDGGLQDYIHDWWNLMDFVMNSLYLATIS :::::::::::::::::::::::::::::: XP_016 MWDGGLQDYIHDWWNLMDFVMNSLYLATIS 10 20 30 460 470 480 490 500 510 pF1KB4 LKIVAFVKYSALNPRESWDMWHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LKIVAFVKYSALNPRESWDMWHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLG 40 50 60 70 80 90 520 530 540 550 560 570 pF1KB4 RMLLDILKFLFIYCLVLLAFANGLNQLYFYYEETKGLTCKGIRCEKQNNAFSTLFETLQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RMLLDILKFLFIYCLVLLAFANGLNQLYFYYEETKGLTCKGIRCEKQNNAFSTLFETLQS 100 110 120 130 140 150 580 590 600 610 620 630 pF1KB4 LFWSIFGLINLYVTNVKAQHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LFWSIFGLINLYVTNVKAQHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADH 160 170 180 190 200 210 640 650 660 670 680 690 pF1KB4 ADIEWKFARTKLWMSYFEEGGTLPTPFNVIPSPKSLWYLIKWIWTHLCKKKMRRKPESFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ADIEWKFARTKLWMSYFEEGGTLPTPFNVIPSPKSLWYLIKWIWTHLCKKKMRRKPESFG 220 230 240 250 260 270 700 710 720 730 740 750 pF1KB4 TIGRRAADNLRRHHQYQEVMRNLVKRYVAAMIRDAKTEEGLTEENFKELKQDISSFRFEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TIGRRAADNLRRHHQYQEVMRNLVKRYVAAMIRDAKTEEGLTEENFKELKQDISSFRFEV 280 290 300 310 320 330 760 770 780 790 800 810 pF1KB4 LGLLRGSKLSTIQSANASKESSNSADSDEKSDSEGNSKDKKKNFSLFDLTTLIHPRSAAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LGLLRGSKLSTIQSANASKESSNSADSDEKSDSEGNSKDKKKNFSLFDLTTLIHPRSAAI 340 350 360 370 380 390 820 830 840 850 860 870 pF1KB4 ASERHNISNGSALVVQEPPREKQRKVNFVTDIKNFGLFHRRSKQNAAEQNANQIFSVSEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ASERHNISNGSALVVQEPPREKQRKVNFVTDIKNFGLFHRRSKQNAAEQNANQIFSVSEE 400 410 420 430 440 450 880 890 900 910 920 930 pF1KB4 VARQQAAGPLERNIQLESRGLASRGDLSIPGLSEQCVLVDHRERNTDTLGLQVGKRVCPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VARQQAAGPLERNIQLESRGLASRGDLSIPGLSEQCVLVDHRERNTDTLGLQVGKRVCPF 460 470 480 490 500 510 940 950 960 970 pF1KB4 KSEKVVVEDTVPIIPKEKHAKEEDSSIDYDLNLPDTVTHEDYVTTRL ::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KSEKVVVEDTVPIIPKEKHAKEEDSSIDYDLNLPDTVTHEDYVTTRL 520 530 540 550 >>XP_016876212 (OMIM: 603651) PREDICTED: short transient (562 aa) initn: 1856 init1: 1856 opt: 3640 Z-score: 3507.2 bits: 659.6 E(85289): 1.3e-188 Smith-Waterman score: 3640; 99.1% identity (99.1% similar) in 562 aa overlap (421-977:1-562) 400 410 420 430 440 450 pF1KB4 DLNRQGPPPTIVEWMILPWVLGFIWGEIKQMWDGGLQDYIHDWWNLMDFVMNSLYLATIS :::::::::::::::::::::::::::::: XP_016 MWDGGLQDYIHDWWNLMDFVMNSLYLATIS 10 20 30 460 470 480 490 500 510 pF1KB4 LKIVAFVKYSALNPRESWDMWHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LKIVAFVKYSALNPRESWDMWHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLG 40 50 60 70 80 90 520 530 540 550 560 570 pF1KB4 RMLLDILKFLFIYCLVLLAFANGLNQLYFYYEETKGLTCKGIRCEKQNNAFSTLFETLQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RMLLDILKFLFIYCLVLLAFANGLNQLYFYYEETKGLTCKGIRCEKQNNAFSTLFETLQS 100 110 120 130 140 150 580 590 600 610 620 630 pF1KB4 LFWSIFGLINLYVTNVKAQHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LFWSIFGLINLYVTNVKAQHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADH 160 170 180 190 200 210 640 650 660 670 680 690 pF1KB4 ADIEWKFARTKLWMSYFEEGGTLPTPFNVIPSPKSLWYLIKWIWTHLCKKKMRRKPESFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ADIEWKFARTKLWMSYFEEGGTLPTPFNVIPSPKSLWYLIKWIWTHLCKKKMRRKPESFG 220 230 240 250 260 270 700 710 720 730 740 pF1KB4 TIG-----RRAADNLRRHHQYQEVMRNLVKRYVAAMIRDAKTEEGLTEENFKELKQDISS ::: :::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TIGVRTQHRRAADNLRRHHQYQEVMRNLVKRYVAAMIRDAKTEEGLTEENFKELKQDISS 280 290 300 310 320 330 750 760 770 780 790 800 pF1KB4 FRFEVLGLLRGSKLSTIQSANASKESSNSADSDEKSDSEGNSKDKKKNFSLFDLTTLIHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FRFEVLGLLRGSKLSTIQSANASKESSNSADSDEKSDSEGNSKDKKKNFSLFDLTTLIHP 340 350 360 370 380 390 810 820 830 840 850 860 pF1KB4 RSAAIASERHNISNGSALVVQEPPREKQRKVNFVTDIKNFGLFHRRSKQNAAEQNANQIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RSAAIASERHNISNGSALVVQEPPREKQRKVNFVTDIKNFGLFHRRSKQNAAEQNANQIF 400 410 420 430 440 450 870 880 890 900 910 920 pF1KB4 SVSEEVARQQAAGPLERNIQLESRGLASRGDLSIPGLSEQCVLVDHRERNTDTLGLQVGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SVSEEVARQQAAGPLERNIQLESRGLASRGDLSIPGLSEQCVLVDHRERNTDTLGLQVGK 460 470 480 490 500 510 930 940 950 960 970 pF1KB4 RVCPFKSEKVVVEDTVPIIPKEKHAKEEDSSIDYDLNLPDTVTHEDYVTTRL :::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RVCPFKSEKVVVEDTVPIIPKEKHAKEEDSSIDYDLNLPDTVTHEDYVTTRL 520 530 540 550 560 977 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 14:24:33 2016 done: Thu Nov 3 14:24:35 2016 Total Scan time: 14.000 Total Display time: 0.320 Function used was FASTA [36.3.4 Apr, 2011]