FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4115, 938 aa 1>>>pF1KB4115 938 - 938 aa - 938 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.7302+/-0.000457; mu= 11.0535+/- 0.028 mean_var=197.8206+/-40.509, 0's: 0 Z-trim(117.0): 144 B-trim: 1329 in 1/51 Lambda= 0.091188 statistics sampled from 28465 (28617) to 28465 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.675), E-opt: 0.2 (0.336), width: 16 Scan time: 14.780 The best scores are: opt bits E(85289) NP_987095 (OMIM: 613369) ATP-dependent RNA helicas ( 938) 6322 845.4 0 XP_016879600 (OMIM: 613369) PREDICTED: ATP-depende ( 938) 6322 845.4 0 XP_006721720 (OMIM: 613369) PREDICTED: ATP-depende ( 938) 6322 845.4 0 NP_031398 (OMIM: 613369) ATP-dependent RNA helicas ( 938) 6322 845.4 0 XP_016879601 (OMIM: 613369) PREDICTED: ATP-depende ( 775) 5214 699.6 1.6e-200 XP_011522561 (OMIM: 613369) PREDICTED: ATP-depende ( 674) 4520 608.2 4.3e-173 NP_001091974 (OMIM: 608469) probable ATP-dependent ( 731) 1253 178.5 1.1e-43 NP_006377 (OMIM: 608469) probable ATP-dependent RN ( 729) 1245 177.4 2.3e-43 NP_004387 (OMIM: 180630) probable ATP-dependent RN ( 614) 1231 175.5 7.2e-43 NP_001307525 (OMIM: 180630) probable ATP-dependent ( 614) 1231 175.5 7.2e-43 NP_001307524 (OMIM: 180630) probable ATP-dependent ( 614) 1231 175.5 7.2e-43 NP_001307526 (OMIM: 180630) probable ATP-dependent ( 614) 1231 175.5 7.2e-43 XP_011534228 (OMIM: 606286) PREDICTED: probable AT ( 604) 1013 146.8 3.1e-34 XP_011534230 (OMIM: 606286) PREDICTED: probable AT ( 529) 1008 146.1 4.4e-34 XP_011534229 (OMIM: 606286) PREDICTED: probable AT ( 529) 1008 146.1 4.4e-34 NP_061135 (OMIM: 606286) probable ATP-dependent RN ( 648) 1008 146.2 5.1e-34 XP_016866492 (OMIM: 606286) PREDICTED: probable AT ( 439) 973 141.4 9.4e-33 XP_011541799 (OMIM: 605281) PREDICTED: probable AT ( 678) 876 128.8 8.9e-29 NP_001160006 (OMIM: 605281) probable ATP-dependent ( 575) 874 128.5 9.5e-29 NP_001136021 (OMIM: 605281) probable ATP-dependent ( 690) 874 128.6 1.1e-28 XP_011541797 (OMIM: 605281) PREDICTED: probable AT ( 698) 874 128.6 1.1e-28 NP_001160005 (OMIM: 605281) probable ATP-dependent ( 704) 874 128.6 1.1e-28 NP_077726 (OMIM: 605281) probable ATP-dependent RN ( 724) 874 128.6 1.1e-28 XP_011508337 (OMIM: 174300,615464) PREDICTED: prob ( 619) 823 121.8 1e-26 XP_016857921 (OMIM: 174300,615464) PREDICTED: prob ( 619) 823 121.8 1e-26 XP_016857920 (OMIM: 174300,615464) PREDICTED: prob ( 619) 823 121.8 1e-26 NP_001026895 (OMIM: 174300,615464) probable ATP-de ( 619) 823 121.8 1e-26 NP_001289481 (OMIM: 400010,415000) ATP-dependent R ( 657) 770 114.9 1.4e-24 NP_004651 (OMIM: 400010,415000) ATP-dependent RNA ( 660) 770 114.9 1.4e-24 NP_001116137 (OMIM: 400010,415000) ATP-dependent R ( 660) 770 114.9 1.4e-24 XP_016884802 (OMIM: 300160,300958) PREDICTED: ATP- ( 476) 767 114.4 1.4e-24 NP_001180346 (OMIM: 300160,300958) ATP-dependent R ( 646) 767 114.5 1.8e-24 NP_001347 (OMIM: 300160,300958) ATP-dependent RNA ( 662) 767 114.5 1.8e-24 XP_016884803 (OMIM: 300160,300958) PREDICTED: ATP- ( 475) 764 114.0 1.9e-24 NP_001180345 (OMIM: 300160,300958) ATP-dependent R ( 661) 764 114.1 2.4e-24 NP_057439 (OMIM: 615428) probable ATP-dependent RN ( 455) 759 113.3 2.9e-24 XP_011542194 (OMIM: 300160,300958) PREDICTED: ATP- ( 598) 743 111.3 1.5e-23 NP_001307110 (OMIM: 174300,615464) probable ATP-de ( 567) 740 110.9 1.9e-23 XP_006711625 (OMIM: 174300,615464) PREDICTED: prob ( 557) 738 110.6 2.3e-23 NP_057306 (OMIM: 608170,616871) probable ATP-depen ( 622) 737 110.5 2.7e-23 NP_001308661 (OMIM: 608170,616871) probable ATP-de ( 496) 724 108.7 7.4e-23 NP_001308759 (OMIM: 608170,616871) probable ATP-de ( 496) 724 108.7 7.4e-23 NP_060365 (OMIM: 616621) probable ATP-dependent RN ( 796) 720 108.4 1.5e-22 NP_001311124 (OMIM: 400010,415000) ATP-dependent R ( 637) 688 104.1 2.4e-21 NP_076977 (OMIM: 611665) ATP-dependent RNA helicas ( 881) 690 104.5 2.5e-21 NP_001104792 (OMIM: 611665) ATP-dependent RNA heli ( 882) 690 104.5 2.5e-21 NP_076950 (OMIM: 610373) ATP-dependent RNA helicas ( 737) 667 101.4 1.8e-20 XP_016872115 (OMIM: 610373) PREDICTED: ATP-depende ( 737) 667 101.4 1.8e-20 NP_055555 (OMIM: 268305,608546) eukaryotic initiat ( 411) 662 100.5 1.9e-20 XP_016872117 (OMIM: 610373) PREDICTED: ATP-depende ( 672) 655 99.8 5e-20 >>NP_987095 (OMIM: 613369) ATP-dependent RNA helicase DD (938 aa) initn: 6322 init1: 6322 opt: 6322 Z-score: 4507.9 bits: 845.4 E(85289): 0 Smith-Waterman score: 6322; 100.0% identity (100.0% similar) in 938 aa overlap (1-938:1-938) 10 20 30 40 50 60 pF1KB4 MNWNKGGPGTKRGFGFGGFAISAGKKEEPKLPQQSHSAFGATSSSSGFGKSAPPQLPSFY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_987 MNWNKGGPGTKRGFGFGGFAISAGKKEEPKLPQQSHSAFGATSSSSGFGKSAPPQLPSFY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 KIGSKRANFDEENAYFEDEEEDSSNVDLPYIPAENSPTRQQFHSKPVDSDSDDDPLEAFM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_987 KIGSKRANFDEENAYFEDEEEDSSNVDLPYIPAENSPTRQQFHSKPVDSDSDDDPLEAFM 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 AEVEDQAARDMKRLEEKDKERKNVKGIRDDIEEEDDQEAYFRYMAENPTAGVVQEEEEDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_987 AEVEDQAARDMKRLEEKDKERKNVKGIRDDIEEEDDQEAYFRYMAENPTAGVVQEEEEDN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 LEYDSDGNPIAPTKKIIDPLPPIDHSEIDYPPFEKNFYNEHEEITNLTPQQLIDLRHKLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_987 LEYDSDGNPIAPTKKIIDPLPPIDHSEIDYPPFEKNFYNEHEEITNLTPQQLIDLRHKLN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 LRVSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_987 LRVSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 SGKTAAFIWPMLIHIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_987 SGKTAAFIWPMLIHIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 YGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMFDMGFEYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_987 YGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMFDMGFEYQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB4 VRSIASHVRPDRQTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_987 VRSIASHVRPDRQTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB4 GPSKWNWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_987 GPSKWNWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKV 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB4 ISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_987 ISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYT 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB4 LLTPKDSNFAGDLVRNLEGANQHVSKELLDLAMQNAWFRKSRFKGGKGKKLNIGGGGLGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_987 LLTPKDSNFAGDLVRNLEGANQHVSKELLDLAMQNAWFRKSRFKGGKGKKLNIGGGGLGY 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB4 RERPGLGSENMDRGNNNVMSNYEAYKPSTGAMGDRLTAMKAAFQSQYKSHFVAASLSNQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_987 RERPGLGSENMDRGNNNVMSNYEAYKPSTGAMGDRLTAMKAAFQSQYKSHFVAASLSNQK 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB4 AGSSAAGASGWTSAGSLNSVPTNSAQQGHNSPDSPVTSAAKGIPGFGNTGNISGAPVTYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_987 AGSSAAGASGWTSAGSLNSVPTNSAQQGHNSPDSPVTSAAKGIPGFGNTGNISGAPVTYP 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB4 SAGAQGVNNTASGNNSREGTGGSNGKRERYTENRGSSRHSHGETGNRHSDSPRHGDGGRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_987 SAGAQGVNNTASGNNSREGTGGSNGKRERYTENRGSSRHSHGETGNRHSDSPRHGDGGRH 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB4 GDGYRHPESSSRHTDGHRHGENRHGGSAGRHGENRGANDGRNGESRKEAFNRESKMEPKM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_987 GDGYRHPESSSRHTDGHRHGENRHGGSAGRHGENRGANDGRNGESRKEAFNRESKMEPKM 850 860 870 880 890 900 910 920 930 pF1KB4 EPKVDSSKMDKVDSKTDKTADGFAVPEPPKRKKSRWDS :::::::::::::::::::::::::::::::::::::: NP_987 EPKVDSSKMDKVDSKTDKTADGFAVPEPPKRKKSRWDS 910 920 930 >>XP_016879600 (OMIM: 613369) PREDICTED: ATP-dependent R (938 aa) initn: 6322 init1: 6322 opt: 6322 Z-score: 4507.9 bits: 845.4 E(85289): 0 Smith-Waterman score: 6322; 100.0% identity (100.0% similar) in 938 aa overlap (1-938:1-938) 10 20 30 40 50 60 pF1KB4 MNWNKGGPGTKRGFGFGGFAISAGKKEEPKLPQQSHSAFGATSSSSGFGKSAPPQLPSFY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MNWNKGGPGTKRGFGFGGFAISAGKKEEPKLPQQSHSAFGATSSSSGFGKSAPPQLPSFY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 KIGSKRANFDEENAYFEDEEEDSSNVDLPYIPAENSPTRQQFHSKPVDSDSDDDPLEAFM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KIGSKRANFDEENAYFEDEEEDSSNVDLPYIPAENSPTRQQFHSKPVDSDSDDDPLEAFM 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 AEVEDQAARDMKRLEEKDKERKNVKGIRDDIEEEDDQEAYFRYMAENPTAGVVQEEEEDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AEVEDQAARDMKRLEEKDKERKNVKGIRDDIEEEDDQEAYFRYMAENPTAGVVQEEEEDN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 LEYDSDGNPIAPTKKIIDPLPPIDHSEIDYPPFEKNFYNEHEEITNLTPQQLIDLRHKLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LEYDSDGNPIAPTKKIIDPLPPIDHSEIDYPPFEKNFYNEHEEITNLTPQQLIDLRHKLN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 LRVSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LRVSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 SGKTAAFIWPMLIHIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SGKTAAFIWPMLIHIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 YGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMFDMGFEYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMFDMGFEYQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB4 VRSIASHVRPDRQTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VRSIASHVRPDRQTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB4 GPSKWNWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GPSKWNWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKV 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB4 ISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYT 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB4 LLTPKDSNFAGDLVRNLEGANQHVSKELLDLAMQNAWFRKSRFKGGKGKKLNIGGGGLGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLTPKDSNFAGDLVRNLEGANQHVSKELLDLAMQNAWFRKSRFKGGKGKKLNIGGGGLGY 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB4 RERPGLGSENMDRGNNNVMSNYEAYKPSTGAMGDRLTAMKAAFQSQYKSHFVAASLSNQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RERPGLGSENMDRGNNNVMSNYEAYKPSTGAMGDRLTAMKAAFQSQYKSHFVAASLSNQK 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB4 AGSSAAGASGWTSAGSLNSVPTNSAQQGHNSPDSPVTSAAKGIPGFGNTGNISGAPVTYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AGSSAAGASGWTSAGSLNSVPTNSAQQGHNSPDSPVTSAAKGIPGFGNTGNISGAPVTYP 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB4 SAGAQGVNNTASGNNSREGTGGSNGKRERYTENRGSSRHSHGETGNRHSDSPRHGDGGRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SAGAQGVNNTASGNNSREGTGGSNGKRERYTENRGSSRHSHGETGNRHSDSPRHGDGGRH 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB4 GDGYRHPESSSRHTDGHRHGENRHGGSAGRHGENRGANDGRNGESRKEAFNRESKMEPKM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GDGYRHPESSSRHTDGHRHGENRHGGSAGRHGENRGANDGRNGESRKEAFNRESKMEPKM 850 860 870 880 890 900 910 920 930 pF1KB4 EPKVDSSKMDKVDSKTDKTADGFAVPEPPKRKKSRWDS :::::::::::::::::::::::::::::::::::::: XP_016 EPKVDSSKMDKVDSKTDKTADGFAVPEPPKRKKSRWDS 910 920 930 >>XP_006721720 (OMIM: 613369) PREDICTED: ATP-dependent R (938 aa) initn: 6322 init1: 6322 opt: 6322 Z-score: 4507.9 bits: 845.4 E(85289): 0 Smith-Waterman score: 6322; 100.0% identity (100.0% similar) in 938 aa overlap (1-938:1-938) 10 20 30 40 50 60 pF1KB4 MNWNKGGPGTKRGFGFGGFAISAGKKEEPKLPQQSHSAFGATSSSSGFGKSAPPQLPSFY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MNWNKGGPGTKRGFGFGGFAISAGKKEEPKLPQQSHSAFGATSSSSGFGKSAPPQLPSFY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 KIGSKRANFDEENAYFEDEEEDSSNVDLPYIPAENSPTRQQFHSKPVDSDSDDDPLEAFM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KIGSKRANFDEENAYFEDEEEDSSNVDLPYIPAENSPTRQQFHSKPVDSDSDDDPLEAFM 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 AEVEDQAARDMKRLEEKDKERKNVKGIRDDIEEEDDQEAYFRYMAENPTAGVVQEEEEDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AEVEDQAARDMKRLEEKDKERKNVKGIRDDIEEEDDQEAYFRYMAENPTAGVVQEEEEDN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 LEYDSDGNPIAPTKKIIDPLPPIDHSEIDYPPFEKNFYNEHEEITNLTPQQLIDLRHKLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LEYDSDGNPIAPTKKIIDPLPPIDHSEIDYPPFEKNFYNEHEEITNLTPQQLIDLRHKLN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 LRVSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LRVSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 SGKTAAFIWPMLIHIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SGKTAAFIWPMLIHIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 YGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMFDMGFEYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 YGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMFDMGFEYQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB4 VRSIASHVRPDRQTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VRSIASHVRPDRQTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB4 GPSKWNWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GPSKWNWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKV 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB4 ISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYT 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB4 LLTPKDSNFAGDLVRNLEGANQHVSKELLDLAMQNAWFRKSRFKGGKGKKLNIGGGGLGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LLTPKDSNFAGDLVRNLEGANQHVSKELLDLAMQNAWFRKSRFKGGKGKKLNIGGGGLGY 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB4 RERPGLGSENMDRGNNNVMSNYEAYKPSTGAMGDRLTAMKAAFQSQYKSHFVAASLSNQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RERPGLGSENMDRGNNNVMSNYEAYKPSTGAMGDRLTAMKAAFQSQYKSHFVAASLSNQK 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB4 AGSSAAGASGWTSAGSLNSVPTNSAQQGHNSPDSPVTSAAKGIPGFGNTGNISGAPVTYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AGSSAAGASGWTSAGSLNSVPTNSAQQGHNSPDSPVTSAAKGIPGFGNTGNISGAPVTYP 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB4 SAGAQGVNNTASGNNSREGTGGSNGKRERYTENRGSSRHSHGETGNRHSDSPRHGDGGRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SAGAQGVNNTASGNNSREGTGGSNGKRERYTENRGSSRHSHGETGNRHSDSPRHGDGGRH 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB4 GDGYRHPESSSRHTDGHRHGENRHGGSAGRHGENRGANDGRNGESRKEAFNRESKMEPKM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GDGYRHPESSSRHTDGHRHGENRHGGSAGRHGENRGANDGRNGESRKEAFNRESKMEPKM 850 860 870 880 890 900 910 920 930 pF1KB4 EPKVDSSKMDKVDSKTDKTADGFAVPEPPKRKKSRWDS :::::::::::::::::::::::::::::::::::::: XP_006 EPKVDSSKMDKVDSKTDKTADGFAVPEPPKRKKSRWDS 910 920 930 >>NP_031398 (OMIM: 613369) ATP-dependent RNA helicase DD (938 aa) initn: 6322 init1: 6322 opt: 6322 Z-score: 4507.9 bits: 845.4 E(85289): 0 Smith-Waterman score: 6322; 100.0% identity (100.0% similar) in 938 aa overlap (1-938:1-938) 10 20 30 40 50 60 pF1KB4 MNWNKGGPGTKRGFGFGGFAISAGKKEEPKLPQQSHSAFGATSSSSGFGKSAPPQLPSFY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_031 MNWNKGGPGTKRGFGFGGFAISAGKKEEPKLPQQSHSAFGATSSSSGFGKSAPPQLPSFY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 KIGSKRANFDEENAYFEDEEEDSSNVDLPYIPAENSPTRQQFHSKPVDSDSDDDPLEAFM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_031 KIGSKRANFDEENAYFEDEEEDSSNVDLPYIPAENSPTRQQFHSKPVDSDSDDDPLEAFM 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 AEVEDQAARDMKRLEEKDKERKNVKGIRDDIEEEDDQEAYFRYMAENPTAGVVQEEEEDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_031 AEVEDQAARDMKRLEEKDKERKNVKGIRDDIEEEDDQEAYFRYMAENPTAGVVQEEEEDN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 LEYDSDGNPIAPTKKIIDPLPPIDHSEIDYPPFEKNFYNEHEEITNLTPQQLIDLRHKLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_031 LEYDSDGNPIAPTKKIIDPLPPIDHSEIDYPPFEKNFYNEHEEITNLTPQQLIDLRHKLN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 LRVSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_031 LRVSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 SGKTAAFIWPMLIHIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_031 SGKTAAFIWPMLIHIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 YGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMFDMGFEYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_031 YGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMFDMGFEYQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB4 VRSIASHVRPDRQTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_031 VRSIASHVRPDRQTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB4 GPSKWNWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_031 GPSKWNWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKV 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB4 ISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_031 ISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYT 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB4 LLTPKDSNFAGDLVRNLEGANQHVSKELLDLAMQNAWFRKSRFKGGKGKKLNIGGGGLGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_031 LLTPKDSNFAGDLVRNLEGANQHVSKELLDLAMQNAWFRKSRFKGGKGKKLNIGGGGLGY 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB4 RERPGLGSENMDRGNNNVMSNYEAYKPSTGAMGDRLTAMKAAFQSQYKSHFVAASLSNQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_031 RERPGLGSENMDRGNNNVMSNYEAYKPSTGAMGDRLTAMKAAFQSQYKSHFVAASLSNQK 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB4 AGSSAAGASGWTSAGSLNSVPTNSAQQGHNSPDSPVTSAAKGIPGFGNTGNISGAPVTYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_031 AGSSAAGASGWTSAGSLNSVPTNSAQQGHNSPDSPVTSAAKGIPGFGNTGNISGAPVTYP 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB4 SAGAQGVNNTASGNNSREGTGGSNGKRERYTENRGSSRHSHGETGNRHSDSPRHGDGGRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_031 SAGAQGVNNTASGNNSREGTGGSNGKRERYTENRGSSRHSHGETGNRHSDSPRHGDGGRH 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB4 GDGYRHPESSSRHTDGHRHGENRHGGSAGRHGENRGANDGRNGESRKEAFNRESKMEPKM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_031 GDGYRHPESSSRHTDGHRHGENRHGGSAGRHGENRGANDGRNGESRKEAFNRESKMEPKM 850 860 870 880 890 900 910 920 930 pF1KB4 EPKVDSSKMDKVDSKTDKTADGFAVPEPPKRKKSRWDS :::::::::::::::::::::::::::::::::::::: NP_031 EPKVDSSKMDKVDSKTDKTADGFAVPEPPKRKKSRWDS 910 920 930 >>XP_016879601 (OMIM: 613369) PREDICTED: ATP-dependent R (775 aa) initn: 5214 init1: 5214 opt: 5214 Z-score: 3721.2 bits: 699.6 E(85289): 1.6e-200 Smith-Waterman score: 5214; 100.0% identity (100.0% similar) in 775 aa overlap (164-938:1-775) 140 150 160 170 180 190 pF1KB4 LEEKDKERKNVKGIRDDIEEEDDQEAYFRYMAENPTAGVVQEEEEDNLEYDSDGNPIAPT :::::::::::::::::::::::::::::: XP_016 MAENPTAGVVQEEEEDNLEYDSDGNPIAPT 10 20 30 200 210 220 230 240 250 pF1KB4 KKIIDPLPPIDHSEIDYPPFEKNFYNEHEEITNLTPQQLIDLRHKLNLRVSGAAPPRPGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KKIIDPLPPIDHSEIDYPPFEKNFYNEHEEITNLTPQQLIDLRHKLNLRVSGAAPPRPGS 40 50 60 70 80 90 260 270 280 290 300 310 pF1KB4 SFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLI 100 110 120 130 140 150 320 330 340 350 360 370 pF1KB4 HIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKAL 160 170 180 190 200 210 380 390 400 410 420 430 pF1KB4 QEGAEIVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMFDMGFEYQVRSIASHVRPDRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QEGAEIVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMFDMGFEYQVRSIASHVRPDRQ 220 230 240 250 260 270 440 450 460 470 480 490 pF1KB4 TLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWNWLTRRLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWNWLTRRLV 280 290 300 310 320 330 500 510 520 530 540 550 pF1KB4 EFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKDIPVLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKDIPVLV 340 350 360 370 380 390 560 570 580 590 600 610 pF1KB4 ATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYTLLTPKDSNFAGDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYTLLTPKDSNFAGDL 400 410 420 430 440 450 620 630 640 650 660 670 pF1KB4 VRNLEGANQHVSKELLDLAMQNAWFRKSRFKGGKGKKLNIGGGGLGYRERPGLGSENMDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VRNLEGANQHVSKELLDLAMQNAWFRKSRFKGGKGKKLNIGGGGLGYRERPGLGSENMDR 460 470 480 490 500 510 680 690 700 710 720 730 pF1KB4 GNNNVMSNYEAYKPSTGAMGDRLTAMKAAFQSQYKSHFVAASLSNQKAGSSAAGASGWTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GNNNVMSNYEAYKPSTGAMGDRLTAMKAAFQSQYKSHFVAASLSNQKAGSSAAGASGWTS 520 530 540 550 560 570 740 750 760 770 780 790 pF1KB4 AGSLNSVPTNSAQQGHNSPDSPVTSAAKGIPGFGNTGNISGAPVTYPSAGAQGVNNTASG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AGSLNSVPTNSAQQGHNSPDSPVTSAAKGIPGFGNTGNISGAPVTYPSAGAQGVNNTASG 580 590 600 610 620 630 800 810 820 830 840 850 pF1KB4 NNSREGTGGSNGKRERYTENRGSSRHSHGETGNRHSDSPRHGDGGRHGDGYRHPESSSRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NNSREGTGGSNGKRERYTENRGSSRHSHGETGNRHSDSPRHGDGGRHGDGYRHPESSSRH 640 650 660 670 680 690 860 870 880 890 900 910 pF1KB4 TDGHRHGENRHGGSAGRHGENRGANDGRNGESRKEAFNRESKMEPKMEPKVDSSKMDKVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TDGHRHGENRHGGSAGRHGENRGANDGRNGESRKEAFNRESKMEPKMEPKVDSSKMDKVD 700 710 720 730 740 750 920 930 pF1KB4 SKTDKTADGFAVPEPPKRKKSRWDS ::::::::::::::::::::::::: XP_016 SKTDKTADGFAVPEPPKRKKSRWDS 760 770 >>XP_011522561 (OMIM: 613369) PREDICTED: ATP-dependent R (674 aa) initn: 4520 init1: 4520 opt: 4520 Z-score: 3228.5 bits: 608.2 E(85289): 4.3e-173 Smith-Waterman score: 4520; 100.0% identity (100.0% similar) in 674 aa overlap (265-938:1-674) 240 250 260 270 280 290 pF1KB4 LRHKLNLRVSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMI :::::::::::::::::::::::::::::: XP_011 MHQIRKSEYTQPTPIQCQGVPVALSGRDMI 10 20 30 300 310 320 330 340 350 pF1KB4 GIAKTGSGKTAAFIWPMLIHIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GIAKTGSGKTAAFIWPMLIHIMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYN 40 50 60 70 80 90 360 370 380 390 400 410 pF1KB4 LRSVAVYGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LRSVAVYGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMFD 100 110 120 130 140 150 420 430 440 450 460 470 pF1KB4 MGFEYQVRSIASHVRPDRQTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MGFEYQVRSIASHVRPDRQTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQI 160 170 180 190 200 210 480 490 500 510 520 530 pF1KB4 VEILHSGPSKWNWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VEILHSGPSKWNWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQ 220 230 240 250 260 270 540 550 560 570 580 590 pF1KB4 SERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGE 280 290 300 310 320 330 600 610 620 630 640 650 pF1KB4 KGVAYTLLTPKDSNFAGDLVRNLEGANQHVSKELLDLAMQNAWFRKSRFKGGKGKKLNIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KGVAYTLLTPKDSNFAGDLVRNLEGANQHVSKELLDLAMQNAWFRKSRFKGGKGKKLNIG 340 350 360 370 380 390 660 670 680 690 700 710 pF1KB4 GGGLGYRERPGLGSENMDRGNNNVMSNYEAYKPSTGAMGDRLTAMKAAFQSQYKSHFVAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GGGLGYRERPGLGSENMDRGNNNVMSNYEAYKPSTGAMGDRLTAMKAAFQSQYKSHFVAA 400 410 420 430 440 450 720 730 740 750 760 770 pF1KB4 SLSNQKAGSSAAGASGWTSAGSLNSVPTNSAQQGHNSPDSPVTSAAKGIPGFGNTGNISG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLSNQKAGSSAAGASGWTSAGSLNSVPTNSAQQGHNSPDSPVTSAAKGIPGFGNTGNISG 460 470 480 490 500 510 780 790 800 810 820 830 pF1KB4 APVTYPSAGAQGVNNTASGNNSREGTGGSNGKRERYTENRGSSRHSHGETGNRHSDSPRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 APVTYPSAGAQGVNNTASGNNSREGTGGSNGKRERYTENRGSSRHSHGETGNRHSDSPRH 520 530 540 550 560 570 840 850 860 870 880 890 pF1KB4 GDGGRHGDGYRHPESSSRHTDGHRHGENRHGGSAGRHGENRGANDGRNGESRKEAFNRES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GDGGRHGDGYRHPESSSRHTDGHRHGENRHGGSAGRHGENRGANDGRNGESRKEAFNRES 580 590 600 610 620 630 900 910 920 930 pF1KB4 KMEPKMEPKVDSSKMDKVDSKTDKTADGFAVPEPPKRKKSRWDS :::::::::::::::::::::::::::::::::::::::::::: XP_011 KMEPKMEPKVDSSKMDKVDSKTDKTADGFAVPEPPKRKKSRWDS 640 650 660 670 >>NP_001091974 (OMIM: 608469) probable ATP-dependent RNA (731 aa) initn: 1232 init1: 714 opt: 1253 Z-score: 905.3 bits: 178.5 E(85289): 1.1e-43 Smith-Waterman score: 1264; 36.2% identity (65.6% similar) in 639 aa overlap (174-789:88-707) 150 160 170 180 190 200 pF1KB4 VKGIRDDIEEEDDQEAYFRYMAENPTAGVVQEEEEDNLEYDSDGNPIAPTKKIIDPLPPI .....: . . :. : ::. .: . NP_001 EPQALPSPAIRAPLPDLYPFGTMRGGGFGDRDRDRDRGGFGARGGGGLPPKKFGNPGERL 60 70 80 90 100 110 210 220 230 240 250 pF1KB4 DHSEIDY---PPFEKNFYNEHEEITNLTPQQLIDLRHKLNLRVSGA-APPRPGSSFAHFG ... : : :::::: :: :.. ::: .. .::.: .. : :. . :.: .: : . NP_001 RKKKWDLSELPKFEKNFYVEHPEVARLTPYEVDELRRKKEITVRGGDVCPKPVFAFHHAN 120 130 140 150 160 170 260 270 280 290 300 310 pF1KB4 FDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLIHIMDQK : . .: . ...:.:::::::: :.:::::::.:::.:::::: :.. : ..:: : NP_001 FPQYVMDVLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVHINHQP 180 190 200 210 220 230 320 330 340 350 360 370 pF1KB4 ELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKALQEGAEI :: ::::: ... ::::: ::.. .:: :.:. .:::. : . :..:.:: NP_001 YLERGDGPICLVLAPTRELAQQVQQVADDYGKCSRLKSTCIYGGAPKGPQIRDLERGVEI 240 250 260 270 280 290 380 390 400 410 420 430 pF1KB4 VVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMFDMGFEYQVRSIASHVRPDRQTLLFSA . ::::::: ... :::.: .:::.::::::.::::: :.:.:....:::::::..:: NP_001 CIATPGRLIDFLESGKTNLRRCTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSA 300 310 320 330 340 350 440 450 460 470 480 490 pF1KB4 TFRKKIEKLARDILIDPIRVVQGDIG-EANEDVTQIVEILHSGPSKWNWLTRRLVEFTSS :. :....::.:.: : .. :.. ::... :::.. . : . : . . :. . NP_001 TWPKEVRQLAEDFLRDYTQINVGNLELSANHNILQIVDVCMESE-KDHKLIQLMEEIMAE 360 370 380 390 400 410 500 510 520 530 540 550 pF1KB4 --GSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATD .....:: : ..:. ....: .::: .: ::. :...:.. :.:.::: NP_001 KENKTIIFVETKRRCDDLTRRMRRDGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIATD 420 430 440 450 460 470 560 570 580 590 600 610 pF1KB4 VAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYTLLTPKDSNFAGDLVRN ::.::::. ..: ::::: . . ..::::::.:. .::.:::..:: . . : .:.. NP_001 VASRGLDVEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPGNLKQARELIKV 480 490 500 510 520 530 620 630 640 650 660 670 pF1KB4 LEGANQHVSKELLDLAMQNAWFRKSRFKGGKGKKLNIGGGGLGYRERPGLGSENM---DR :: ::: .. .:..:. : :: : : :: :: . .. :. :. NP_001 LEEANQAINPKLMQLV-------DHRGGGGGGGK----GGRSRYRTTSSANNPNLMYQDE 540 550 560 570 580 680 690 700 710 720 pF1KB4 GNNNVMSNYEAYKPSTGAMGDRLTAMKAAFQ--SQY---KSHFVAA----SLSNQKAGSS . . . .. . ..... :: . .:.. : : .: : : . .. :.. NP_001 CDRRLRGVKDGGRRDSASYRDRSETDRAGYANGSGYGSPNSAFGAQAGQYTYGQGTYGAA 590 600 610 620 630 640 730 740 750 760 770 780 pF1KB4 AAGASGWTS----AGSLNSVPTNSAQQGHNSPDSPVTSAAKGIPGFGNTGNISGAPVTYP : :.:..:. ::. .. :.:. :..: :... . :.: .:. .. NP_001 AYGTSSYTAQEYGAGTYGASSTTST--GRSSQ-----SSSQQFSGIGRSGQQPQPLMSQQ 650 660 670 680 690 790 800 810 820 830 840 pF1KB4 SAGAQGVNNTASGNNSREGTGGSNGKRERYTENRGSSRHSHGETGNRHSDSPRHGDGGRH : :..: NP_001 FAQPPGATNMIGYMGQTAYQYPPPPPPPPPSRK 700 710 720 730 >>NP_006377 (OMIM: 608469) probable ATP-dependent RNA he (729 aa) initn: 1228 init1: 714 opt: 1245 Z-score: 899.6 bits: 177.4 E(85289): 2.3e-43 Smith-Waterman score: 1265; 36.1% identity (65.9% similar) in 640 aa overlap (174-789:88-705) 150 160 170 180 190 200 pF1KB4 VKGIRDDIEEEDDQEAYFRYMAENPTAGVVQEEEEDNLEYDSDGNPIAPTKKIIDPLPPI .....: . . :. : ::. .: . NP_006 EPQALPSPAIRAPLPDLYPFGTMRGGGFGDRDRDRDRGGFGARGGGGLPPKKFGNPGERL 60 70 80 90 100 110 210 220 230 240 250 pF1KB4 DHSEIDY---PPFEKNFYNEHEEITNLTPQQLIDLRHKLNLRVSGA-APPRPGSSFAHFG ... : : :::::: :: :.. ::: .. .::.: .. : :. . :.: .: : . NP_006 RKKKWDLSELPKFEKNFYVEHPEVARLTPYEVDELRRKKEITVRGGDVCPKPVFAFHHAN 120 130 140 150 160 170 260 270 280 290 300 310 pF1KB4 FDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLIHIMDQK : . .: . ...:.:::::::: :.:::::::.:::.:::::: :.. : ..:: : NP_006 FPQYVMDVLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVHINHQP 180 190 200 210 220 230 320 330 340 350 360 370 pF1KB4 ELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKALQEGAEI :: ::::: ... ::::: ::.. .:: :.:. .:::. : . :..:.:: NP_006 YLERGDGPICLVLAPTRELAQQVQQVADDYGKCSRLKSTCIYGGAPKGPQIRDLERGVEI 240 250 260 270 280 290 380 390 400 410 420 430 pF1KB4 VVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMFDMGFEYQVRSIASHVRPDRQTLLFSA . ::::::: ... :::.: .:::.::::::.::::: :.:.:....:::::::..:: NP_006 CIATPGRLIDFLESGKTNLRRCTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSA 300 310 320 330 340 350 440 450 460 470 480 490 pF1KB4 TFRKKIEKLARDILIDPIRVVQGDIG-EANEDVTQIVEILHSGPSKWNWLTRRLVEFTSS :. :....::.:.: : .. :.. ::... :::.. . : . : . . :. . NP_006 TWPKEVRQLAEDFLRDYTQINVGNLELSANHNILQIVDVCMESE-KDHKLIQLMEEIMAE 360 370 380 390 400 410 500 510 520 530 540 550 pF1KB4 --GSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATD .....:: : ..:. ....: .::: .: ::. :...:.. :.:.::: NP_006 KENKTIIFVETKRRCDDLTRRMRRDGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIATD 420 430 440 450 460 470 560 570 580 590 600 610 pF1KB4 VAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYTLLTPKDSNFAGDLVRN ::.::::. ..: ::::: . . ..::::::.:. .::.:::..:: . . : .:.. NP_006 VASRGLDVEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPGNLKQARELIKV 480 490 500 510 520 530 620 630 640 650 660 670 pF1KB4 LEGANQHVSKELLDLAMQNAWFRKSRFKGGKGKKLNIGGGGLG-YRERPGLGSENM---D :: ::: .. .:..:. . .:: : :::: . :: . .. :. : NP_006 LEEANQAINPKLMQLVDH---------RGGGG-----GGGGRSRYRTTSSANNPNLMYQD 540 550 560 570 580 680 690 700 710 720 pF1KB4 RGNNNVMSNYEAYKPSTGAMGDRLTAMKAAFQ--SQY---KSHFVAA----SLSNQKAGS . . . . .. . ..... :: . .:.. : : .: : : . .. :. NP_006 ECDRRLRGVKDGGRRDSASYRDRSETDRAGYANGSGYGSPNSAFGAQAGQYTYGQGTYGA 590 600 610 620 630 640 730 740 750 760 770 pF1KB4 SAAGASGWTS----AGSLNSVPTNSAQQGHNSPDSPVTSAAKGIPGFGNTGNISGAPVTY .: :.:..:. ::. .. :.:. :..: :... . :.: .:. .. NP_006 AAYGTSSYTAQEYGAGTYGASSTTST--GRSSQ-----SSSQQFSGIGRSGQQPQPLMSQ 650 660 670 680 690 780 790 800 810 820 830 pF1KB4 PSAGAQGVNNTASGNNSREGTGGSNGKRERYTENRGSSRHSHGETGNRHSDSPRHGDGGR : :..: NP_006 QFAQPPGATNMIGYMGQTAYQYPPPPPPPPPSRK 700 710 720 >>NP_004387 (OMIM: 180630) probable ATP-dependent RNA he (614 aa) initn: 1147 init1: 790 opt: 1231 Z-score: 890.6 bits: 175.5 E(85289): 7.2e-43 Smith-Waterman score: 1231; 37.3% identity (67.9% similar) in 585 aa overlap (192-764:37-607) 170 180 190 200 210 220 pF1KB4 RYMAENPTAGVVQEEEEDNLEYDSDGNPIAPTKKIIDPLPPIDHSEIDYPPFEKNFYNEH : .:.. .: . : ::::::.:: NP_004 DRDRGRDRGFGAPRFGGSRAGPLSGKKFGNPGEKLVKKKWNLD----ELPKFEKNFYQEH 10 20 30 40 50 60 230 240 250 260 270 280 pF1KB4 EEITNLTPQQLIDLRHKLNLRVSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQC ... : :.. :.. .. : : :.: .: . .: ..: : ....:.:: :: NP_004 PDLARRTAQEVETYRRSKEITVRGHNCPKPVLNFYEANFPANVMDVIARQNFTEPTAIQA 70 80 90 100 110 120 290 300 310 320 330 340 pF1KB4 QGVPVALSGRDMIGIAKTGSGKTAAFIWPMLIHIMDQKELEPGDGPIAVIVCPTRELCQQ :: :::::: ::.:.:.:::::: ... : ..:: : :: ::::: ... ::::: :: NP_004 QGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGPICLVLAPTRELAQQ 130 140 150 160 170 180 350 360 370 380 390 400 pF1KB4 IHAECKRFGKAYNLRSVAVYGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRV .. .. .: :.:. .:::. : . :..:.:: . ::::::: .. :::.:. NP_004 VQQVAAEYCRACRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLECGKTNLRRT 190 200 210 220 230 240 410 420 430 440 450 460 pF1KB4 SYLVFDEADRMFDMGFEYQVRSIASHVRPDRQTLLFSATFRKKIEKLARDILIDPIRVVQ .:::.::::::.::::: :.:.:....:::::::..:::. :....::.:.: : :.. NP_004 TYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLKDYIHINI 250 260 270 280 290 300 470 480 490 500 510 pF1KB4 GDIG-EANEDVTQIVEILHSGPSKWNWLTRRLVEFTSS--GSVLLFVTKKANAEELANNL : . ::... :::.. :. : . : : . :. : .....:: : .::. .. NP_004 GALELSANHNILQIVDVCHD-VEKDEKLIRLMEEIMSEKENKTIVFVETKRRCDELTRKM 310 320 330 340 350 360 520 530 540 550 560 570 pF1KB4 KQEGHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARD ...: .::: .:.::. :...::. :.:.:::::.::::. ..: ::::: . NP_004 RRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKFVINYDYPNS 370 380 390 400 410 420 580 590 600 610 620 630 pF1KB4 IDTHTHRIGRTGRAGEKGVAYTLLTPKDSNFAGDLVRNLEGANQHVSKELLDLAMQNAWF . . ::::::.:. . :.:::..::.. . ..::. :. ::: .. .::.: ... NP_004 SEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVSDLISVLREANQAINPKLLQL-VEDRGS 430 440 450 460 470 480 640 650 660 670 680 690 pF1KB4 RKSRFKGG----KGKKLNIG--GGGLGYRERPGLGSENMDRGNNNVMSNYEAYKPSTGAM .:: .:: . . . : :: .:.: ::.::: ..... . : ..:.. NP_004 GRSRGRGGMKDDRRDRYSAGKRGGFNTFRDR-----ENYDRGYSSLLKRDFGAKTQNGVY 490 500 510 520 530 700 710 720 730 740 750 pF1KB4 GDRLTAMKAAFQSQYKSHFVAASL-SNQKAGSSAAGASGWTSAGSLNSVPTNSAQQGHNS . . ...: :.. : . .:. ... .:. : .. . :: .::. ..... NP_004 SAA-NYTNGSFGSNFVSAGIQTSFRTGNPTGTYQNGYDSTQQYGS--NVPNMHNGMNQQA 540 550 560 570 580 590 760 770 780 790 800 pF1KB4 PDSPVTSAAK--GIPGFGNTGNISGAPVTYPSAGAQGVNNTASGNNSREGTGGSNGKRER :.:.:: : : NP_004 YAYPATAAAPMIGYPMPTGYSQ 600 610 >>NP_001307525 (OMIM: 180630) probable ATP-dependent RNA (614 aa) initn: 1147 init1: 790 opt: 1231 Z-score: 890.6 bits: 175.5 E(85289): 7.2e-43 Smith-Waterman score: 1231; 37.3% identity (67.9% similar) in 585 aa overlap (192-764:37-607) 170 180 190 200 210 220 pF1KB4 RYMAENPTAGVVQEEEEDNLEYDSDGNPIAPTKKIIDPLPPIDHSEIDYPPFEKNFYNEH : .:.. .: . : ::::::.:: NP_001 DRDRGRDRGFGAPRFGGSRAGPLSGKKFGNPGEKLVKKKWNLD----ELPKFEKNFYQEH 10 20 30 40 50 60 230 240 250 260 270 280 pF1KB4 EEITNLTPQQLIDLRHKLNLRVSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQC ... : :.. :.. .. : : :.: .: . .: ..: : ....:.:: :: NP_001 PDLARRTAQEVETYRRSKEITVRGHNCPKPVLNFYEANFPANVMDVIARQNFTEPTAIQA 70 80 90 100 110 120 290 300 310 320 330 340 pF1KB4 QGVPVALSGRDMIGIAKTGSGKTAAFIWPMLIHIMDQKELEPGDGPIAVIVCPTRELCQQ :: :::::: ::.:.:.:::::: ... : ..:: : :: ::::: ... ::::: :: NP_001 QGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGPICLVLAPTRELAQQ 130 140 150 160 170 180 350 360 370 380 390 400 pF1KB4 IHAECKRFGKAYNLRSVAVYGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRV .. .. .: :.:. .:::. : . :..:.:: . ::::::: .. :::.:. NP_001 VQQVAAEYCRACRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLECGKTNLRRT 190 200 210 220 230 240 410 420 430 440 450 460 pF1KB4 SYLVFDEADRMFDMGFEYQVRSIASHVRPDRQTLLFSATFRKKIEKLARDILIDPIRVVQ .:::.::::::.::::: :.:.:....:::::::..:::. :....::.:.: : :.. NP_001 TYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLKDYIHINI 250 260 270 280 290 300 470 480 490 500 510 pF1KB4 GDIG-EANEDVTQIVEILHSGPSKWNWLTRRLVEFTSS--GSVLLFVTKKANAEELANNL : . ::... :::.. :. : . : : . :. : .....:: : .::. .. NP_001 GALELSANHNILQIVDVCHD-VEKDEKLIRLMEEIMSEKENKTIVFVETKRRCDELTRKM 310 320 330 340 350 360 520 530 540 550 560 570 pF1KB4 KQEGHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARD ...: .::: .:.::. :...::. :.:.:::::.::::. ..: ::::: . NP_001 RRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKFVINYDYPNS 370 380 390 400 410 420 580 590 600 610 620 630 pF1KB4 IDTHTHRIGRTGRAGEKGVAYTLLTPKDSNFAGDLVRNLEGANQHVSKELLDLAMQNAWF . . ::::::.:. . :.:::..::.. . ..::. :. ::: .. .::.: ... NP_001 SEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVSDLISVLREANQAINPKLLQL-VEDRGS 430 440 450 460 470 480 640 650 660 670 680 690 pF1KB4 RKSRFKGG----KGKKLNIG--GGGLGYRERPGLGSENMDRGNNNVMSNYEAYKPSTGAM .:: .:: . . . : :: .:.: ::.::: ..... . : ..:.. NP_001 GRSRGRGGMKDDRRDRYSAGKRGGFNTFRDR-----ENYDRGYSSLLKRDFGAKTQNGVY 490 500 510 520 530 700 710 720 730 740 750 pF1KB4 GDRLTAMKAAFQSQYKSHFVAASL-SNQKAGSSAAGASGWTSAGSLNSVPTNSAQQGHNS . . ...: :.. : . .:. ... .:. : .. . :: .::. ..... NP_001 SAA-NYTNGSFGSNFVSAGIQTSFRTGNPTGTYQNGYDSTQQYGS--NVPNMHNGMNQQA 540 550 560 570 580 590 760 770 780 790 800 pF1KB4 PDSPVTSAAK--GIPGFGNTGNISGAPVTYPSAGAQGVNNTASGNNSREGTGGSNGKRER :.:.:: : : NP_001 YAYPATAAAPMIGYPMPTGYSQ 600 610 938 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 14:25:17 2016 done: Thu Nov 3 14:25:20 2016 Total Scan time: 14.780 Total Display time: 0.300 Function used was FASTA [36.3.4 Apr, 2011]