FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4120, 451 aa 1>>>pF1KB4120 451 - 451 aa - 451 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 14.1646+/-0.000494; mu= -21.9295+/- 0.031 mean_var=541.0932+/-117.323, 0's: 0 Z-trim(123.9): 75 B-trim: 3123 in 2/57 Lambda= 0.055136 statistics sampled from 44513 (44596) to 44513 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.783), E-opt: 0.2 (0.523), width: 16 Scan time: 10.240 The best scores are: opt bits E(85289) NP_001171591 (OMIM: 603050) abl interactor 1 isofo ( 451) 3053 257.1 6.9e-68 NP_001012769 (OMIM: 603050) abl interactor 1 isofo ( 452) 3041 256.2 1.3e-67 NP_001171592 (OMIM: 603050) abl interactor 1 isofo ( 446) 2996 252.6 1.6e-66 XP_006717424 (OMIM: 603050) PREDICTED: abl interac ( 447) 2984 251.6 3.1e-66 NP_001171590 (OMIM: 603050) abl interactor 1 isofo ( 480) 2255 193.7 9.3e-49 NP_001012768 (OMIM: 603050) abl interactor 1 isofo ( 481) 2232 191.8 3.3e-48 NP_001012770 (OMIM: 603050) abl interactor 1 isofo ( 476) 2220 190.9 6.4e-48 XP_005252390 (OMIM: 603050) PREDICTED: abl interac ( 475) 2198 189.1 2.1e-47 XP_016858624 (OMIM: 606442) PREDICTED: abl interac ( 445) 2190 188.5 3.2e-47 XP_005246283 (OMIM: 606442) PREDICTED: abl interac ( 446) 2188 188.3 3.5e-47 XP_006712245 (OMIM: 606442) PREDICTED: abl interac ( 451) 2134 184.0 7e-46 XP_006712244 (OMIM: 606442) PREDICTED: abl interac ( 452) 2132 183.9 7.9e-46 XP_016858625 (OMIM: 606442) PREDICTED: abl interac ( 444) 2024 175.3 3e-43 XP_016858623 (OMIM: 606442) PREDICTED: abl interac ( 445) 2022 175.1 3.3e-43 XP_016858621 (OMIM: 606442) PREDICTED: abl interac ( 451) 1966 170.6 7.4e-42 XP_016870947 (OMIM: 603050) PREDICTED: abl interac ( 478) 1836 160.3 1e-38 XP_006717423 (OMIM: 603050) PREDICTED: abl interac ( 479) 1834 160.2 1.1e-38 NP_001171593 (OMIM: 603050) abl interactor 1 isofo ( 422) 1831 159.9 1.2e-38 XP_006717422 (OMIM: 603050) PREDICTED: abl interac ( 507) 1825 159.5 1.9e-38 NP_005461 (OMIM: 603050) abl interactor 1 isoform ( 508) 1819 159.0 2.7e-38 XP_011517591 (OMIM: 603050) PREDICTED: abl interac ( 302) 1797 157.1 6e-38 XP_016870948 (OMIM: 603050) PREDICTED: abl interac ( 290) 1789 156.4 9.1e-38 NP_001171594 (OMIM: 603050) abl interactor 1 isofo ( 393) 1793 156.8 9.2e-38 XP_005252389 (OMIM: 603050) PREDICTED: abl interac ( 503) 1771 155.2 3.8e-37 NP_001171595 (OMIM: 603050) abl interactor 1 isofo ( 388) 1736 152.3 2.1e-36 XP_005246282 (OMIM: 606442) PREDICTED: abl interac ( 458) 1667 146.9 1.1e-34 XP_016858620 (OMIM: 606442) PREDICTED: abl interac ( 457) 1661 146.4 1.5e-34 XP_016858615 (OMIM: 606442) PREDICTED: abl interac ( 473) 1622 143.3 1.3e-33 XP_016858614 (OMIM: 606442) PREDICTED: abl interac ( 474) 1618 143.0 1.7e-33 NP_005750 (OMIM: 606442) abl interactor 2 isoform ( 475) 1616 142.8 1.9e-33 XP_016858616 (OMIM: 606442) PREDICTED: abl interac ( 473) 1612 142.5 2.3e-33 XP_016858613 (OMIM: 606442) PREDICTED: abl interac ( 474) 1610 142.3 2.6e-33 NP_001171587 (OMIM: 603050) abl interactor 1 isofo ( 496) 1598 141.4 5.2e-33 NP_001269861 (OMIM: 606442) abl interactor 2 isofo ( 390) 1590 140.7 6.7e-33 XP_006712248 (OMIM: 606442) PREDICTED: abl interac ( 401) 1590 140.7 6.8e-33 NP_001269856 (OMIM: 606442) abl interactor 2 isofo ( 401) 1590 140.7 6.8e-33 XP_006712243 (OMIM: 606442) PREDICTED: abl interac ( 481) 1507 134.2 7.6e-31 NP_001269855 (OMIM: 606442) abl interactor 2 isofo ( 507) 1428 127.9 6.2e-29 XP_005246275 (OMIM: 606442) PREDICTED: abl interac ( 536) 1428 127.9 6.5e-29 XP_016858610 (OMIM: 606442) PREDICTED: abl interac ( 512) 1372 123.4 1.4e-27 XP_016858609 (OMIM: 606442) PREDICTED: abl interac ( 540) 1372 123.5 1.4e-27 XP_016858607 (OMIM: 606442) PREDICTED: abl interac ( 541) 1372 123.5 1.4e-27 NP_001269854 (OMIM: 606442) abl interactor 2 isofo ( 513) 1370 123.3 1.5e-27 XP_016858608 (OMIM: 606442) PREDICTED: abl interac ( 540) 1370 123.3 1.6e-27 XP_006712237 (OMIM: 606442) PREDICTED: abl interac ( 541) 1370 123.3 1.6e-27 XP_005246274 (OMIM: 606442) PREDICTED: abl interac ( 542) 1370 123.3 1.6e-27 XP_016858619 (OMIM: 606442) PREDICTED: abl interac ( 463) 1132 104.3 7.1e-22 XP_016858618 (OMIM: 606442) PREDICTED: abl interac ( 464) 1126 103.8 9.9e-22 XP_016858627 (OMIM: 606442) PREDICTED: abl interac ( 431) 1116 103.0 1.6e-21 XP_011508774 (OMIM: 606442) PREDICTED: abl interac ( 492) 1103 102.0 3.7e-21 >>NP_001171591 (OMIM: 603050) abl interactor 1 isoform g (451 aa) initn: 3053 init1: 3053 opt: 3053 Z-score: 1339.7 bits: 257.1 E(85289): 6.9e-68 Smith-Waterman score: 3053; 100.0% identity (100.0% similar) in 451 aa overlap (1-451:1-451) 10 20 30 40 50 60 pF1KB4 MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLAS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 VAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 THKIIAPANMERPVRYIRKPIDYTVLDDVGHGVKWLKAKHGNNQPARTGTLSRTNPPTQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 THKIIAPANMERPVRYIRKPIDYTVLDDVGHGVKWLKAKHGNNQPARTGTLSRTNPPTQK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 PPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 GSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPAPGSAPGSQYGTMTRQISRHNSTTSST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPAPGSAPGSQYGTMTRQISRHNSTTSST 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 SSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSIADSPTPPPPPPPDDIPMFDDSPPPPPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSIADSPTPPPPPPPDDIPMFDDSPPPPPPP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 PVDYEDEEAAVVQYNDPYADGDPAWAPKNYIEKVVAIYDYTKDKDDELSFMEGAIIYVIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PVDYEDEEAAVVQYNDPYADGDPAWAPKNYIEKVVAIYDYTKDKDDELSFMEGAIIYVIK 370 380 390 400 410 420 430 440 450 pF1KB4 KNDDGWYEGVCNRVTGLFPGNYVESIMHYTD ::::::::::::::::::::::::::::::: NP_001 KNDDGWYEGVCNRVTGLFPGNYVESIMHYTD 430 440 450 >>NP_001012769 (OMIM: 603050) abl interactor 1 isoform c (452 aa) initn: 1907 init1: 1907 opt: 3041 Z-score: 1334.6 bits: 256.2 E(85289): 1.3e-67 Smith-Waterman score: 3041; 99.8% identity (99.8% similar) in 452 aa overlap (1-451:1-452) 10 20 30 40 50 60 pF1KB4 MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLAS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 VAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 THKIIAPANMERPVRYIRKPIDYTVLDDVGHGVKWLKAKHGNNQPARTGTLSRTNPPTQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 THKIIAPANMERPVRYIRKPIDYTVLDDVGHGVKWLKAKHGNNQPARTGTLSRTNPPTQK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 PPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHS 190 200 210 220 230 240 250 260 270 280 290 pF1KB4 GSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPA-PGSAPGSQYGTMTRQISRHNSTTSS :::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::: NP_001 GSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPAAPGSAPGSQYGTMTRQISRHNSTTSS 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB4 TSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSIADSPTPPPPPPPDDIPMFDDSPPPPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSIADSPTPPPPPPPDDIPMFDDSPPPPPP 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB4 PPVDYEDEEAAVVQYNDPYADGDPAWAPKNYIEKVVAIYDYTKDKDDELSFMEGAIIYVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PPVDYEDEEAAVVQYNDPYADGDPAWAPKNYIEKVVAIYDYTKDKDDELSFMEGAIIYVI 370 380 390 400 410 420 420 430 440 450 pF1KB4 KKNDDGWYEGVCNRVTGLFPGNYVESIMHYTD :::::::::::::::::::::::::::::::: NP_001 KKNDDGWYEGVCNRVTGLFPGNYVESIMHYTD 430 440 450 >>NP_001171592 (OMIM: 603050) abl interactor 1 isoform h (446 aa) initn: 2060 init1: 2060 opt: 2996 Z-score: 1315.3 bits: 252.6 E(85289): 1.6e-66 Smith-Waterman score: 2996; 98.9% identity (98.9% similar) in 451 aa overlap (1-451:1-446) 10 20 30 40 50 60 pF1KB4 MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLAS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 VAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 THKIIAPANMERPVRYIRKPIDYTVLDDVGHGVKWLKAKHGNNQPARTGTLSRTNPPTQK :::::::::::::::::::::::::::::::::: ::::::::::::::::::::: NP_001 THKIIAPANMERPVRYIRKPIDYTVLDDVGHGVK-----HGNNQPARTGTLSRTNPPTQK 130 140 150 160 170 190 200 210 220 230 240 pF1KB4 PPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHS 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB4 GSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPAPGSAPGSQYGTMTRQISRHNSTTSST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPAPGSAPGSQYGTMTRQISRHNSTTSST 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB4 SSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSIADSPTPPPPPPPDDIPMFDDSPPPPPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSIADSPTPPPPPPPDDIPMFDDSPPPPPPP 300 310 320 330 340 350 370 380 390 400 410 420 pF1KB4 PVDYEDEEAAVVQYNDPYADGDPAWAPKNYIEKVVAIYDYTKDKDDELSFMEGAIIYVIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PVDYEDEEAAVVQYNDPYADGDPAWAPKNYIEKVVAIYDYTKDKDDELSFMEGAIIYVIK 360 370 380 390 400 410 430 440 450 pF1KB4 KNDDGWYEGVCNRVTGLFPGNYVESIMHYTD ::::::::::::::::::::::::::::::: NP_001 KNDDGWYEGVCNRVTGLFPGNYVESIMHYTD 420 430 440 >>XP_006717424 (OMIM: 603050) PREDICTED: abl interactor (447 aa) initn: 1265 init1: 1265 opt: 2984 Z-score: 1310.1 bits: 251.6 E(85289): 3.1e-66 Smith-Waterman score: 2984; 98.7% identity (98.7% similar) in 452 aa overlap (1-451:1-447) 10 20 30 40 50 60 pF1KB4 MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLAS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 VAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 THKIIAPANMERPVRYIRKPIDYTVLDDVGHGVKWLKAKHGNNQPARTGTLSRTNPPTQK :::::::::::::::::::::::::::::::::: ::::::::::::::::::::: XP_006 THKIIAPANMERPVRYIRKPIDYTVLDDVGHGVK-----HGNNQPARTGTLSRTNPPTQK 130 140 150 160 170 190 200 210 220 230 240 pF1KB4 PPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHS 180 190 200 210 220 230 250 260 270 280 290 pF1KB4 GSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPA-PGSAPGSQYGTMTRQISRHNSTTSS :::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::: XP_006 GSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPAAPGSAPGSQYGTMTRQISRHNSTTSS 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB4 TSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSIADSPTPPPPPPPDDIPMFDDSPPPPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSIADSPTPPPPPPPDDIPMFDDSPPPPPP 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB4 PPVDYEDEEAAVVQYNDPYADGDPAWAPKNYIEKVVAIYDYTKDKDDELSFMEGAIIYVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PPVDYEDEEAAVVQYNDPYADGDPAWAPKNYIEKVVAIYDYTKDKDDELSFMEGAIIYVI 360 370 380 390 400 410 420 430 440 450 pF1KB4 KKNDDGWYEGVCNRVTGLFPGNYVESIMHYTD :::::::::::::::::::::::::::::::: XP_006 KKNDDGWYEGVCNRVTGLFPGNYVESIMHYTD 420 430 440 >>NP_001171590 (OMIM: 603050) abl interactor 1 isoform f (480 aa) initn: 2295 init1: 2222 opt: 2255 Z-score: 996.3 bits: 193.7 E(85289): 9.3e-49 Smith-Waterman score: 2985; 94.0% identity (94.0% similar) in 480 aa overlap (1-451:1-480) 10 20 30 40 50 60 pF1KB4 MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLAS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 VAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 THKIIAPANMERPVRYIRKPIDYTVLDDVGHGVKWLKAKHGNNQPARTGTLSRTNPPTQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 THKIIAPANMERPVRYIRKPIDYTVLDDVGHGVKWLKAKHGNNQPARTGTLSRTNPPTQK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 PPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 GSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPAPGSAPGSQYGTMTRQISRHNSTTSST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPAPGSAPGSQYGTMTRQISRHNSTTSST 250 260 270 280 290 300 310 320 330 pF1KB4 SSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSI---------------------------- :::::::::::::::::::::::::::::::: NP_001 SSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTPQIPLTGFVARVQEN 310 320 330 340 350 360 340 350 360 370 380 390 pF1KB4 -ADSPTPPPPPPPDDIPMFDDSPPPPPPPPVDYEDEEAAVVQYNDPYADGDPAWAPKNYI ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IADSPTPPPPPPPDDIPMFDDSPPPPPPPPVDYEDEEAAVVQYNDPYADGDPAWAPKNYI 370 380 390 400 410 420 400 410 420 430 440 450 pF1KB4 EKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVESIMHYTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVESIMHYTD 430 440 450 460 470 480 >>NP_001012768 (OMIM: 603050) abl interactor 1 isoform b (481 aa) initn: 2245 init1: 1825 opt: 2232 Z-score: 986.4 bits: 191.8 E(85289): 3.3e-48 Smith-Waterman score: 2973; 93.8% identity (93.8% similar) in 481 aa overlap (1-451:1-481) 10 20 30 40 50 60 pF1KB4 MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLAS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 VAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 THKIIAPANMERPVRYIRKPIDYTVLDDVGHGVKWLKAKHGNNQPARTGTLSRTNPPTQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 THKIIAPANMERPVRYIRKPIDYTVLDDVGHGVKWLKAKHGNNQPARTGTLSRTNPPTQK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 PPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHS 190 200 210 220 230 240 250 260 270 280 290 pF1KB4 GSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPA-PGSAPGSQYGTMTRQISRHNSTTSS :::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::: NP_001 GSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPAAPGSAPGSQYGTMTRQISRHNSTTSS 250 260 270 280 290 300 300 310 320 330 pF1KB4 TSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSI--------------------------- ::::::::::::::::::::::::::::::::: NP_001 TSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTPQIPLTGFVARVQE 310 320 330 340 350 360 340 350 360 370 380 390 pF1KB4 --ADSPTPPPPPPPDDIPMFDDSPPPPPPPPVDYEDEEAAVVQYNDPYADGDPAWAPKNY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NIADSPTPPPPPPPDDIPMFDDSPPPPPPPPVDYEDEEAAVVQYNDPYADGDPAWAPKNY 370 380 390 400 410 420 400 410 420 430 440 450 pF1KB4 IEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVESIMHYT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVESIMHYT 430 440 450 460 470 480 pF1KB4 D : NP_001 D >>NP_001012770 (OMIM: 603050) abl interactor 1 isoform d (476 aa) initn: 2219 init1: 981 opt: 2220 Z-score: 981.3 bits: 190.9 E(85289): 6.4e-48 Smith-Waterman score: 2916; 92.7% identity (92.7% similar) in 481 aa overlap (1-451:1-476) 10 20 30 40 50 60 pF1KB4 MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLAS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 VAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 THKIIAPANMERPVRYIRKPIDYTVLDDVGHGVKWLKAKHGNNQPARTGTLSRTNPPTQK :::::::::::::::::::::::::::::::::: ::::::::::::::::::::: NP_001 THKIIAPANMERPVRYIRKPIDYTVLDDVGHGVK-----HGNNQPARTGTLSRTNPPTQK 130 140 150 160 170 190 200 210 220 230 240 pF1KB4 PPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHS 180 190 200 210 220 230 250 260 270 280 290 pF1KB4 GSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPA-PGSAPGSQYGTMTRQISRHNSTTSS :::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::: NP_001 GSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPAAPGSAPGSQYGTMTRQISRHNSTTSS 240 250 260 270 280 290 300 310 320 330 pF1KB4 TSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSI--------------------------- ::::::::::::::::::::::::::::::::: NP_001 TSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTPQIPLTGFVARVQE 300 310 320 330 340 350 340 350 360 370 380 390 pF1KB4 --ADSPTPPPPPPPDDIPMFDDSPPPPPPPPVDYEDEEAAVVQYNDPYADGDPAWAPKNY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NIADSPTPPPPPPPDDIPMFDDSPPPPPPPPVDYEDEEAAVVQYNDPYADGDPAWAPKNY 360 370 380 390 400 410 400 410 420 430 440 450 pF1KB4 IEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVESIMHYT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVESIMHYT 420 430 440 450 460 470 pF1KB4 D : NP_001 D >>XP_005252390 (OMIM: 603050) PREDICTED: abl interactor (475 aa) initn: 2252 init1: 1229 opt: 2198 Z-score: 971.9 bits: 189.1 E(85289): 2.1e-47 Smith-Waterman score: 2928; 92.9% identity (92.9% similar) in 480 aa overlap (1-451:1-475) 10 20 30 40 50 60 pF1KB4 MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLAS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 VAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 THKIIAPANMERPVRYIRKPIDYTVLDDVGHGVKWLKAKHGNNQPARTGTLSRTNPPTQK :::::::::::::::::::::::::::::::::: ::::::::::::::::::::: XP_005 THKIIAPANMERPVRYIRKPIDYTVLDDVGHGVK-----HGNNQPARTGTLSRTNPPTQK 130 140 150 160 170 190 200 210 220 230 240 pF1KB4 PPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHS 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB4 GSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPAPGSAPGSQYGTMTRQISRHNSTTSST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GSSGGSGSRENSGSSSIGIPIAVPTPSPPTIGPAPGSAPGSQYGTMTRQISRHNSTTSST 240 250 260 270 280 290 310 320 330 pF1KB4 SSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSI---------------------------- :::::::::::::::::::::::::::::::: XP_005 SSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTPQIPLTGFVARVQEN 300 310 320 330 340 350 340 350 360 370 380 390 pF1KB4 -ADSPTPPPPPPPDDIPMFDDSPPPPPPPPVDYEDEEAAVVQYNDPYADGDPAWAPKNYI ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IADSPTPPPPPPPDDIPMFDDSPPPPPPPPVDYEDEEAAVVQYNDPYADGDPAWAPKNYI 360 370 380 390 400 410 400 410 420 430 440 450 pF1KB4 EKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVESIMHYTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVESIMHYTD 420 430 440 450 460 470 >>XP_016858624 (OMIM: 606442) PREDICTED: abl interactor (445 aa) initn: 2329 init1: 891 opt: 2190 Z-score: 968.8 bits: 188.5 E(85289): 3.2e-47 Smith-Waterman score: 2190; 73.0% identity (86.7% similar) in 460 aa overlap (1-451:1-445) 10 20 30 40 50 60 pF1KB4 MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLAS :::::::::::::.:.:::..:: :: ::::::::::::..::..::::::::::::::: XP_016 MAELQMLLEEEIPGGRRALFDSYTNLERVADYCENNYIQSADKQRALEETKAYTTQSLAS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 VAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR ::: ::.:::::::.::::::::::::::::::::::::::::::::::::::::::::: XP_016 VAYLINTLANNVLQMLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 THKIIAPANMERPVRYIRKPIDYTVLDDVGHGVKWLKAKHGNNQPARTGTLSRTNPPTQK :::::::::.::::::::::::::.:::.::::: ..: . : : ::.::::: XP_016 THKIIAPANLERPVRYIRKPIDYTILDDIGHGVKV------STQNMKMGGLPRTTPPTQK 130 140 150 160 170 190 200 210 220 230 pF1KB4 PPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPAR--LGSQHSPGRTASLNQRPRT ::::::::.:::::..::.:::::.::.:::::. ::.: ::.:: ::::.::: :: XP_016 PPSPPMSGKGTLGRHSPYRTLEPVRPPVVPNDYVPSPTRNMAPSQQSPVRTASVNQRNRT 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB4 HS-GSSGGS------GSRENSGSSSIGIPIAVPTPSPPTIGPAPGSAPGSQYGTMTRQIS .: :::::: .:::::::.:.:.::::::::::.. :. : :. .:.: : XP_016 YSSGSSGGSHPSSRSSSRENSGSGSVGVPIAVPTPSPPSVFPG---HP-VQFYSMNRPAS 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB4 RHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSIADSPTPPPPPPPDDIPMFD ::. : . .: ::: ::.:.: : : ..::::.:::: ..:. :::::: . :.:: XP_016 RHTPPTIG-GSLPYRRPPSITSQTSLQNQMNGGPFYSQNPVSDT---PPPPPPVEEPVFD 300 310 320 330 340 360 370 380 390 400 410 pF1KB4 DSPPPPPPPPVDYEDEEAAVVQYNDPYADGDPAWAPKNYIEKVVAIYDYTKDKDDELSFM .:::::::: :::.::::::.:.::::. :: :::..:.:::::::::::::.:::::. XP_016 ESPPPPPPPE-DYEEEEAAVVEYSDPYAEEDPPWAPRSYLEKVVAIYDYTKDKEDELSFQ 350 360 370 380 390 400 420 430 440 450 pF1KB4 EGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVESIMHYTD ::::::::::::::::::: : ::::::::::::::::.. XP_016 EGAIIYVIKKNDDGWYEGVMNGVTGLFPGNYVESIMHYSE 410 420 430 440 >>XP_005246283 (OMIM: 606442) PREDICTED: abl interactor (446 aa) initn: 1995 init1: 932 opt: 2188 Z-score: 967.9 bits: 188.3 E(85289): 3.5e-47 Smith-Waterman score: 2188; 72.9% identity (86.6% similar) in 461 aa overlap (1-451:1-446) 10 20 30 40 50 60 pF1KB4 MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLAS :::::::::::::.:.:::..:: :: ::::::::::::..::..::::::::::::::: XP_005 MAELQMLLEEEIPGGRRALFDSYTNLERVADYCENNYIQSADKQRALEETKAYTTQSLAS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 VAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR ::: ::.:::::::.::::::::::::::::::::::::::::::::::::::::::::: XP_005 VAYLINTLANNVLQMLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 THKIIAPANMERPVRYIRKPIDYTVLDDVGHGVKWLKAKHGNNQPARTGTLSRTNPPTQK :::::::::.::::::::::::::.:::.::::: ..: . : : ::.::::: XP_005 THKIIAPANLERPVRYIRKPIDYTILDDIGHGVKV------STQNMKMGGLPRTTPPTQK 130 140 150 160 170 190 200 210 220 230 pF1KB4 PPSPPMSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPAR--LGSQHSPGRTASLNQRPRT ::::::::.:::::..::.:::::.::.:::::. ::.: ::.:: ::::.::: :: XP_005 PPSPPMSGKGTLGRHSPYRTLEPVRPPVVPNDYVPSPTRNMAPSQQSPVRTASVNQRNRT 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB4 HS--GSSGGS------GSRENSGSSSIGIPIAVPTPSPPTIGPAPGSAPGSQYGTMTRQI .: :::::: .:::::::.:.:.::::::::::.. :. : :. .:.: XP_005 YSSSGSSGGSHPSSRSSSRENSGSGSVGVPIAVPTPSPPSVFPG---HP-VQFYSMNRPA 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB4 SRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSIADSPTPPPPPPPDDIPMF :::. : . .: ::: ::.:.: : : ..::::.:::: ..:. :::::: . :.: XP_005 SRHTPPTIG-GSLPYRRPPSITSQTSLQNQMNGGPFYSQNPVSDT---PPPPPPVEEPVF 300 310 320 330 340 360 370 380 390 400 410 pF1KB4 DDSPPPPPPPPVDYEDEEAAVVQYNDPYADGDPAWAPKNYIEKVVAIYDYTKDKDDELSF :.:::::::: :::.::::::.:.::::. :: :::..:.:::::::::::::.::::: XP_005 DESPPPPPPPE-DYEEEEAAVVEYSDPYAEEDPPWAPRSYLEKVVAIYDYTKDKEDELSF 350 360 370 380 390 400 420 430 440 450 pF1KB4 MEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVESIMHYTD .::::::::::::::::::: : ::::::::::::::::.. XP_005 QEGAIIYVIKKNDDGWYEGVMNGVTGLFPGNYVESIMHYSE 410 420 430 440 451 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 05:38:43 2016 done: Sat Nov 5 05:38:45 2016 Total Scan time: 10.240 Total Display time: 0.090 Function used was FASTA [36.3.4 Apr, 2011]