FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4122, 614 aa 1>>>pF1KB4122 614 - 614 aa - 614 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.4998+/-0.000426; mu= 19.2691+/- 0.026 mean_var=92.8795+/-19.115, 0's: 0 Z-trim(112.4): 185 B-trim: 926 in 1/57 Lambda= 0.133080 statistics sampled from 21129 (21370) to 21129 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.607), E-opt: 0.2 (0.251), width: 16 Scan time: 10.570 The best scores are: opt bits E(85289) NP_004387 (OMIM: 180630) probable ATP-dependent RN ( 614) 4159 809.4 0 NP_001307525 (OMIM: 180630) probable ATP-dependent ( 614) 4159 809.4 0 NP_001307524 (OMIM: 180630) probable ATP-dependent ( 614) 4159 809.4 0 NP_001307526 (OMIM: 180630) probable ATP-dependent ( 614) 4062 790.8 0 NP_001091974 (OMIM: 608469) probable ATP-dependent ( 731) 2676 524.7 4.2e-148 NP_006377 (OMIM: 608469) probable ATP-dependent RN ( 729) 2666 522.8 1.6e-147 XP_016879601 (OMIM: 613369) PREDICTED: ATP-depende ( 775) 1231 247.3 1.4e-64 NP_031398 (OMIM: 613369) ATP-dependent RNA helicas ( 938) 1231 247.4 1.7e-64 XP_006721720 (OMIM: 613369) PREDICTED: ATP-depende ( 938) 1231 247.4 1.7e-64 NP_987095 (OMIM: 613369) ATP-dependent RNA helicas ( 938) 1231 247.4 1.7e-64 XP_016879600 (OMIM: 613369) PREDICTED: ATP-depende ( 938) 1231 247.4 1.7e-64 XP_011534230 (OMIM: 606286) PREDICTED: probable AT ( 529) 1171 235.6 3.2e-61 XP_011534229 (OMIM: 606286) PREDICTED: probable AT ( 529) 1171 235.6 3.2e-61 NP_061135 (OMIM: 606286) probable ATP-dependent RN ( 648) 1171 235.7 3.7e-61 XP_011534228 (OMIM: 606286) PREDICTED: probable AT ( 604) 1150 231.7 5.8e-60 XP_016866492 (OMIM: 606286) PREDICTED: probable AT ( 439) 1118 225.4 3.2e-58 XP_011522561 (OMIM: 613369) PREDICTED: ATP-depende ( 674) 1116 225.2 5.8e-58 XP_011541799 (OMIM: 605281) PREDICTED: probable AT ( 678) 1000 202.9 2.9e-51 NP_001136021 (OMIM: 605281) probable ATP-dependent ( 690) 1000 202.9 3e-51 XP_011541797 (OMIM: 605281) PREDICTED: probable AT ( 698) 1000 202.9 3e-51 NP_001160005 (OMIM: 605281) probable ATP-dependent ( 704) 1000 202.9 3e-51 NP_077726 (OMIM: 605281) probable ATP-dependent RN ( 724) 1000 202.9 3.1e-51 NP_001160006 (OMIM: 605281) probable ATP-dependent ( 575) 998 202.5 3.4e-51 XP_016884803 (OMIM: 300160,300958) PREDICTED: ATP- ( 475) 991 201.0 7.5e-51 NP_001180345 (OMIM: 300160,300958) ATP-dependent R ( 661) 992 201.4 8.4e-51 XP_016884802 (OMIM: 300160,300958) PREDICTED: ATP- ( 476) 989 200.7 9.8e-51 NP_001180346 (OMIM: 300160,300958) ATP-dependent R ( 646) 990 201.0 1.1e-50 NP_001347 (OMIM: 300160,300958) ATP-dependent RNA ( 662) 990 201.0 1.1e-50 NP_001289481 (OMIM: 400010,415000) ATP-dependent R ( 657) 973 197.7 1e-49 NP_004651 (OMIM: 400010,415000) ATP-dependent RNA ( 660) 973 197.7 1e-49 NP_001116137 (OMIM: 400010,415000) ATP-dependent R ( 660) 973 197.7 1e-49 XP_011542194 (OMIM: 300160,300958) PREDICTED: ATP- ( 598) 947 192.7 3.1e-48 NP_001311124 (OMIM: 400010,415000) ATP-dependent R ( 637) 850 174.1 1.3e-42 XP_016857920 (OMIM: 174300,615464) PREDICTED: prob ( 619) 819 168.1 8e-41 XP_011508337 (OMIM: 174300,615464) PREDICTED: prob ( 619) 819 168.1 8e-41 XP_016857921 (OMIM: 174300,615464) PREDICTED: prob ( 619) 819 168.1 8e-41 NP_001026895 (OMIM: 174300,615464) probable ATP-de ( 619) 819 168.1 8e-41 NP_001307110 (OMIM: 174300,615464) probable ATP-de ( 567) 738 152.5 3.6e-36 XP_006711625 (OMIM: 174300,615464) PREDICTED: prob ( 557) 736 152.1 4.6e-36 NP_057439 (OMIM: 615428) probable ATP-dependent RN ( 455) 726 150.1 1.5e-35 NP_001308661 (OMIM: 608170,616871) probable ATP-de ( 496) 724 149.8 2.1e-35 NP_001308759 (OMIM: 608170,616871) probable ATP-de ( 496) 724 149.8 2.1e-35 NP_001243839 (OMIM: 606357) nucleolar RNA helicase ( 715) 725 150.1 2.4e-35 NP_057306 (OMIM: 608170,616871) probable ATP-depen ( 622) 724 149.9 2.5e-35 NP_004719 (OMIM: 606357) nucleolar RNA helicase 2 ( 783) 725 150.2 2.6e-35 NP_076950 (OMIM: 610373) ATP-dependent RNA helicas ( 737) 696 144.6 1.2e-33 XP_016872115 (OMIM: 610373) PREDICTED: ATP-depende ( 737) 696 144.6 1.2e-33 XP_005270205 (OMIM: 610373) PREDICTED: ATP-depende ( 672) 693 144.0 1.6e-33 XP_016872118 (OMIM: 610373) PREDICTED: ATP-depende ( 672) 693 144.0 1.6e-33 XP_016872116 (OMIM: 610373) PREDICTED: ATP-depende ( 672) 693 144.0 1.6e-33 >>NP_004387 (OMIM: 180630) probable ATP-dependent RNA he (614 aa) initn: 4159 init1: 4159 opt: 4159 Z-score: 4319.6 bits: 809.4 E(85289): 0 Smith-Waterman score: 4159; 100.0% identity (100.0% similar) in 614 aa overlap (1-614:1-614) 10 20 30 40 50 60 pF1KB4 MSGYSSDRDRGRDRGFGAPRFGGSRAGPLSGKKFGNPGEKLVKKKWNLDELPKFEKNFYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 MSGYSSDRDRGRDRGFGAPRFGGSRAGPLSGKKFGNPGEKLVKKKWNLDELPKFEKNFYQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 EHPDLARRTAQEVETYRRSKEITVRGHNCPKPVLNFYEANFPANVMDVIARQNFTEPTAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 EHPDLARRTAQEVETYRRSKEITVRGHNCPKPVLNFYEANFPANVMDVIARQNFTEPTAI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 QAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGPICLVLAPTRELA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 QAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGPICLVLAPTRELA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 QQVQQVAAEYCRACRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLECGKTNLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 QQVQQVAAEYCRACRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLECGKTNLR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 RTTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLKDYIHI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 RTTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLKDYIHI 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 NIGALELSANHNILQIVDVCHDVEKDEKLIRLMEEIMSEKENKTIVFVETKRRCDELTRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 NIGALELSANHNILQIVDVCHDVEKDEKLIRLMEEIMSEKENKTIVFVETKRRCDELTRK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 MRRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKFVINYDYPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 MRRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKFVINYDYPN 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB4 SSEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVSDLISVLREANQAINPKLLQLVEDRGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 SSEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVSDLISVLREANQAINPKLLQLVEDRGS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB4 GRSRGRGGMKDDRRDRYSAGKRGGFNTFRDRENYDRGYSSLLKRDFGAKTQNGVYSAANY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 GRSRGRGGMKDDRRDRYSAGKRGGFNTFRDRENYDRGYSSLLKRDFGAKTQNGVYSAANY 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB4 TNGSFGSNFVSAGIQTSFRTGNPTGTYQNGYDSTQQYGSNVPNMHNGMNQQAYAYPATAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 TNGSFGSNFVSAGIQTSFRTGNPTGTYQNGYDSTQQYGSNVPNMHNGMNQQAYAYPATAA 550 560 570 580 590 600 610 pF1KB4 APMIGYPMPTGYSQ :::::::::::::: NP_004 APMIGYPMPTGYSQ 610 >>NP_001307525 (OMIM: 180630) probable ATP-dependent RNA (614 aa) initn: 4159 init1: 4159 opt: 4159 Z-score: 4319.6 bits: 809.4 E(85289): 0 Smith-Waterman score: 4159; 100.0% identity (100.0% similar) in 614 aa overlap (1-614:1-614) 10 20 30 40 50 60 pF1KB4 MSGYSSDRDRGRDRGFGAPRFGGSRAGPLSGKKFGNPGEKLVKKKWNLDELPKFEKNFYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSGYSSDRDRGRDRGFGAPRFGGSRAGPLSGKKFGNPGEKLVKKKWNLDELPKFEKNFYQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 EHPDLARRTAQEVETYRRSKEITVRGHNCPKPVLNFYEANFPANVMDVIARQNFTEPTAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EHPDLARRTAQEVETYRRSKEITVRGHNCPKPVLNFYEANFPANVMDVIARQNFTEPTAI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 QAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGPICLVLAPTRELA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGPICLVLAPTRELA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 QQVQQVAAEYCRACRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLECGKTNLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QQVQQVAAEYCRACRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLECGKTNLR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 RTTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLKDYIHI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RTTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLKDYIHI 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 NIGALELSANHNILQIVDVCHDVEKDEKLIRLMEEIMSEKENKTIVFVETKRRCDELTRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NIGALELSANHNILQIVDVCHDVEKDEKLIRLMEEIMSEKENKTIVFVETKRRCDELTRK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 MRRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKFVINYDYPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MRRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKFVINYDYPN 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB4 SSEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVSDLISVLREANQAINPKLLQLVEDRGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVSDLISVLREANQAINPKLLQLVEDRGS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB4 GRSRGRGGMKDDRRDRYSAGKRGGFNTFRDRENYDRGYSSLLKRDFGAKTQNGVYSAANY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GRSRGRGGMKDDRRDRYSAGKRGGFNTFRDRENYDRGYSSLLKRDFGAKTQNGVYSAANY 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB4 TNGSFGSNFVSAGIQTSFRTGNPTGTYQNGYDSTQQYGSNVPNMHNGMNQQAYAYPATAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TNGSFGSNFVSAGIQTSFRTGNPTGTYQNGYDSTQQYGSNVPNMHNGMNQQAYAYPATAA 550 560 570 580 590 600 610 pF1KB4 APMIGYPMPTGYSQ :::::::::::::: NP_001 APMIGYPMPTGYSQ 610 >>NP_001307524 (OMIM: 180630) probable ATP-dependent RNA (614 aa) initn: 4159 init1: 4159 opt: 4159 Z-score: 4319.6 bits: 809.4 E(85289): 0 Smith-Waterman score: 4159; 100.0% identity (100.0% similar) in 614 aa overlap (1-614:1-614) 10 20 30 40 50 60 pF1KB4 MSGYSSDRDRGRDRGFGAPRFGGSRAGPLSGKKFGNPGEKLVKKKWNLDELPKFEKNFYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSGYSSDRDRGRDRGFGAPRFGGSRAGPLSGKKFGNPGEKLVKKKWNLDELPKFEKNFYQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 EHPDLARRTAQEVETYRRSKEITVRGHNCPKPVLNFYEANFPANVMDVIARQNFTEPTAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EHPDLARRTAQEVETYRRSKEITVRGHNCPKPVLNFYEANFPANVMDVIARQNFTEPTAI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 QAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGPICLVLAPTRELA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGPICLVLAPTRELA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 QQVQQVAAEYCRACRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLECGKTNLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QQVQQVAAEYCRACRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLECGKTNLR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 RTTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLKDYIHI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RTTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLKDYIHI 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 NIGALELSANHNILQIVDVCHDVEKDEKLIRLMEEIMSEKENKTIVFVETKRRCDELTRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NIGALELSANHNILQIVDVCHDVEKDEKLIRLMEEIMSEKENKTIVFVETKRRCDELTRK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 MRRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKFVINYDYPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MRRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKFVINYDYPN 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB4 SSEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVSDLISVLREANQAINPKLLQLVEDRGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVSDLISVLREANQAINPKLLQLVEDRGS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB4 GRSRGRGGMKDDRRDRYSAGKRGGFNTFRDRENYDRGYSSLLKRDFGAKTQNGVYSAANY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GRSRGRGGMKDDRRDRYSAGKRGGFNTFRDRENYDRGYSSLLKRDFGAKTQNGVYSAANY 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB4 TNGSFGSNFVSAGIQTSFRTGNPTGTYQNGYDSTQQYGSNVPNMHNGMNQQAYAYPATAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TNGSFGSNFVSAGIQTSFRTGNPTGTYQNGYDSTQQYGSNVPNMHNGMNQQAYAYPATAA 550 560 570 580 590 600 610 pF1KB4 APMIGYPMPTGYSQ :::::::::::::: NP_001 APMIGYPMPTGYSQ 610 >>NP_001307526 (OMIM: 180630) probable ATP-dependent RNA (614 aa) initn: 4053 init1: 4053 opt: 4062 Z-score: 4219.0 bits: 790.8 E(85289): 0 Smith-Waterman score: 4062; 99.2% identity (99.5% similar) in 606 aa overlap (9-614:9-614) 10 20 30 40 50 60 pF1KB4 MSGYSSDRDRGRDRGFGAPRFGGSRAGPLSGKKFGNPGEKLVKKKWNLDELPKFEKNFYQ :.: . ::::::::::::::::::::::::::::::::::::::::::::: NP_001 MKAGRFEADEGTSVRFGAPRFGGSRAGPLSGKKFGNPGEKLVKKKWNLDELPKFEKNFYQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 EHPDLARRTAQEVETYRRSKEITVRGHNCPKPVLNFYEANFPANVMDVIARQNFTEPTAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EHPDLARRTAQEVETYRRSKEITVRGHNCPKPVLNFYEANFPANVMDVIARQNFTEPTAI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 QAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGPICLVLAPTRELA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGPICLVLAPTRELA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 QQVQQVAAEYCRACRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLECGKTNLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QQVQQVAAEYCRACRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLECGKTNLR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 RTTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLKDYIHI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RTTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLKDYIHI 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 NIGALELSANHNILQIVDVCHDVEKDEKLIRLMEEIMSEKENKTIVFVETKRRCDELTRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NIGALELSANHNILQIVDVCHDVEKDEKLIRLMEEIMSEKENKTIVFVETKRRCDELTRK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 MRRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKFVINYDYPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MRRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKFVINYDYPN 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB4 SSEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVSDLISVLREANQAINPKLLQLVEDRGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVSDLISVLREANQAINPKLLQLVEDRGS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB4 GRSRGRGGMKDDRRDRYSAGKRGGFNTFRDRENYDRGYSSLLKRDFGAKTQNGVYSAANY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GRSRGRGGMKDDRRDRYSAGKRGGFNTFRDRENYDRGYSSLLKRDFGAKTQNGVYSAANY 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB4 TNGSFGSNFVSAGIQTSFRTGNPTGTYQNGYDSTQQYGSNVPNMHNGMNQQAYAYPATAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TNGSFGSNFVSAGIQTSFRTGNPTGTYQNGYDSTQQYGSNVPNMHNGMNQQAYAYPATAA 550 560 570 580 590 600 610 pF1KB4 APMIGYPMPTGYSQ :::::::::::::: NP_001 APMIGYPMPTGYSQ 610 >>NP_001091974 (OMIM: 608469) probable ATP-dependent RNA (731 aa) initn: 2426 init1: 2305 opt: 2676 Z-score: 2779.8 bits: 524.7 E(85289): 4.2e-148 Smith-Waterman score: 2721; 67.9% identity (81.1% similar) in 645 aa overlap (3-612:83-717) 10 20 30 pF1KB4 MSGYSSDRDRGRDRGFGAPRFGGSRAGPLSGK : .:::: :::: : ::. .: : : NP_001 VVTRPEPQALPSPAIRAPLPDLYPFGTMRGGGFGDRDRDRDRG-G---FGARGGGGLPPK 60 70 80 90 100 40 50 60 70 80 90 pF1KB4 KFGNPGEKLVKKKWNLDELPKFEKNFYQEHPDLARRTAQEVETYRRSKEITVRGHN-CPK :::::::.: ::::.:.:::::::::: :::..:: : ::. ::.::::::: . ::: NP_001 KFGNPGERLRKKKWDLSELPKFEKNFYVEHPEVARLTPYEVDELRRKKEITVRGGDVCPK 110 120 130 140 150 160 100 110 120 130 140 150 pF1KB4 PVLNFYEANFPANVMDVIARQNFTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLP ::. :..:::: ::::. :.::::: :: ::.:.:::: ::::.:::::::::.:::: NP_001 PVFAFHHANFPQYVMDVLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLP 170 180 190 200 210 220 160 170 180 190 200 210 pF1KB4 AIVHINHQPFLERGDGPICLVLAPTRELAQQVQQVAAEYCRACRLKSTCIYGGAPKGPQI :::::::::.:::::::::::::::::::::::::: .: . ::::::::::::::::: NP_001 AIVHINHQPYLERGDGPICLVLAPTRELAQQVQQVADDYGKCSRLKSTCIYGGAPKGPQI 230 240 250 260 270 280 220 230 240 250 260 270 pF1KB4 RDLERGVEICIATPGRLIDFLECGKTNLRRTTYLVLDEADRMLDMGFEPQIRKIVDQIRP :::::::::::::::::::::: ::::::: ::::::::::::::::::::::::::::: NP_001 RDLERGVEICIATPGRLIDFLESGKTNLRRCTYLVLDEADRMLDMGFEPQIRKIVDQIRP 290 300 310 320 330 340 280 290 300 310 320 330 pF1KB4 DRQTLMWSATWPKEVRQLAEDFLKDYIHINIGALELSANHNILQIVDVCHDVEKDEKLIR :::::::::::::::::::::::.:: .::.: :::::::::::::::: . :::.:::. NP_001 DRQTLMWSATWPKEVRQLAEDFLRDYTQINVGNLELSANHNILQIVDVCMESEKDHKLIQ 350 360 370 380 390 400 340 350 360 370 380 390 pF1KB4 LMEEIMSEKENKTIVFVETKRRCDELTRKMRRDGWPAMGIHGDKSQQERDWVLNEFKHGK ::::::.:::::::.:::::::::.:::.::::::::: ::::::: :::::::::. :: NP_001 LMEEIMAEKENKTIIFVETKRRCDDLTRRMRRDGWPAMCIHGDKSQPERDWVLNEFRSGK 410 420 430 440 450 460 400 410 420 430 440 450 pF1KB4 APILIATDVASRGLDVEDVKFVINYDYPNSSEDYIHRIGRTARSTKTGTAYTFFTPNNIK ::::::::::::::::::::::::::::::::::.::::::::::. :::::::::.:.: NP_001 APILIATDVASRGLDVEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPGNLK 470 480 490 500 510 520 460 470 480 490 pF1KB4 QVSDLISVLREANQAINPKLLQLVEDRGSGRSRGRGG---------------MKDDRRDR :. .::.::.::::::::::.:::. ::.: . :.:: : .:. :: NP_001 QARELIKVLEEANQAINPKLMQLVDHRGGGGGGGKGGRSRYRTTSSANNPNLMYQDECDR 530 540 550 560 570 580 500 510 520 530 540 pF1KB4 YSAG-KRGGFN---TFRDRENYDR-------GYSSLLKRDFGAKTQN-----GVYSAANY : : :: ..::: . :: ::.: . :::.. . :.:.:: : NP_001 RLRGVKDGGRRDSASYRDRSETDRAGYANGSGYGSP-NSAFGAQAGQYTYGQGTYGAAAY 590 600 610 620 630 640 550 560 570 580 590 pF1KB4 TNGSFGSNFVSAGIQTSFRTGNPTGTYQNGYDSTQQY---GSNVPNMHNGMNQQAYAYPA ..:. .. .:: .. ... :.: ... .:.::. : . . . :.:: .: : NP_001 GTSSYTAQEYGAG---TYGASSTTSTGRSSQSSSQQFSGIGRSGQQPQPLMSQQ-FAQPP 650 660 670 680 690 700 600 610 pF1KB4 TAAAPMIGYPMPTGYSQ .:. :::: :.: NP_001 -GATNMIGYMGQTAYQYPPPPPPPPPSRK 710 720 730 >>NP_006377 (OMIM: 608469) probable ATP-dependent RNA he (729 aa) initn: 2407 init1: 2286 opt: 2666 Z-score: 2769.5 bits: 522.8 E(85289): 1.6e-147 Smith-Waterman score: 2713; 68.3% identity (81.2% similar) in 643 aa overlap (3-612:83-715) 10 20 30 pF1KB4 MSGYSSDRDRGRDRGFGAPRFGGSRAGPLSGK : .:::: :::: : ::. .: : : NP_006 VVTRPEPQALPSPAIRAPLPDLYPFGTMRGGGFGDRDRDRDRG-G---FGARGGGGLPPK 60 70 80 90 100 40 50 60 70 80 90 pF1KB4 KFGNPGEKLVKKKWNLDELPKFEKNFYQEHPDLARRTAQEVETYRRSKEITVRGHN-CPK :::::::.: ::::.:.:::::::::: :::..:: : ::. ::.::::::: . ::: NP_006 KFGNPGERLRKKKWDLSELPKFEKNFYVEHPEVARLTPYEVDELRRKKEITVRGGDVCPK 110 120 130 140 150 160 100 110 120 130 140 150 pF1KB4 PVLNFYEANFPANVMDVIARQNFTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLP ::. :..:::: ::::. :.::::: :: ::.:.:::: ::::.:::::::::.:::: NP_006 PVFAFHHANFPQYVMDVLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLP 170 180 190 200 210 220 160 170 180 190 200 210 pF1KB4 AIVHINHQPFLERGDGPICLVLAPTRELAQQVQQVAAEYCRACRLKSTCIYGGAPKGPQI :::::::::.:::::::::::::::::::::::::: .: . ::::::::::::::::: NP_006 AIVHINHQPYLERGDGPICLVLAPTRELAQQVQQVADDYGKCSRLKSTCIYGGAPKGPQI 230 240 250 260 270 280 220 230 240 250 260 270 pF1KB4 RDLERGVEICIATPGRLIDFLECGKTNLRRTTYLVLDEADRMLDMGFEPQIRKIVDQIRP :::::::::::::::::::::: ::::::: ::::::::::::::::::::::::::::: NP_006 RDLERGVEICIATPGRLIDFLESGKTNLRRCTYLVLDEADRMLDMGFEPQIRKIVDQIRP 290 300 310 320 330 340 280 290 300 310 320 330 pF1KB4 DRQTLMWSATWPKEVRQLAEDFLKDYIHINIGALELSANHNILQIVDVCHDVEKDEKLIR :::::::::::::::::::::::.:: .::.: :::::::::::::::: . :::.:::. NP_006 DRQTLMWSATWPKEVRQLAEDFLRDYTQINVGNLELSANHNILQIVDVCMESEKDHKLIQ 350 360 370 380 390 400 340 350 360 370 380 390 pF1KB4 LMEEIMSEKENKTIVFVETKRRCDELTRKMRRDGWPAMGIHGDKSQQERDWVLNEFKHGK ::::::.:::::::.:::::::::.:::.::::::::: ::::::: :::::::::. :: NP_006 LMEEIMAEKENKTIIFVETKRRCDDLTRRMRRDGWPAMCIHGDKSQPERDWVLNEFRSGK 410 420 430 440 450 460 400 410 420 430 440 450 pF1KB4 APILIATDVASRGLDVEDVKFVINYDYPNSSEDYIHRIGRTARSTKTGTAYTFFTPNNIK ::::::::::::::::::::::::::::::::::.::::::::::. :::::::::.:.: NP_006 APILIATDVASRGLDVEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPGNLK 470 480 490 500 510 520 460 470 480 490 pF1KB4 QVSDLISVLREANQAINPKLLQLVEDRGSG-----RSRGRGG--------MKDDRRDRYS :. .::.::.::::::::::.:::. ::.: ::: : : .:. :: NP_006 QARELIKVLEEANQAINPKLMQLVDHRGGGGGGGGRSRYRTTSSANNPNLMYQDECDRRL 530 540 550 560 570 580 500 510 520 530 540 pF1KB4 AG-KRGGFN---TFRDRENYDR-------GYSSLLKRDFGAKTQN-----GVYSAANYTN : : :: ..::: . :: ::.: . :::.. . :.:.:: : . NP_006 RGVKDGGRRDSASYRDRSETDRAGYANGSGYGSP-NSAFGAQAGQYTYGQGTYGAAAYGT 590 600 610 620 630 640 550 560 570 580 590 pF1KB4 GSFGSNFVSAGIQTSFRTGNPTGTYQNGYDSTQQY---GSNVPNMHNGMNQQAYAYPATA .:. .. .:: .. ... :.: ... .:.::. : . . . :.:: .: : . NP_006 SSYTAQEYGAG---TYGASSTTSTGRSSQSSSQQFSGIGRSGQQPQPLMSQQ-FAQPP-G 650 660 670 680 690 700 600 610 pF1KB4 AAPMIGYPMPTGYSQ :. :::: :.: NP_006 ATNMIGYMGQTAYQYPPPPPPPPPSRK 710 720 >>XP_016879601 (OMIM: 613369) PREDICTED: ATP-dependent R (775 aa) initn: 1147 init1: 790 opt: 1231 Z-score: 1280.1 bits: 247.3 E(85289): 1.4e-64 Smith-Waterman score: 1231; 37.3% identity (67.9% similar) in 585 aa overlap (37-607:29-601) 10 20 30 40 50 60 pF1KB4 DRDRGRDRGFGAPRFGGSRAGPLSGKKFGNPGEKLVKKKWNLD----ELPKFEKNFYQEH : .:.. .: . : ::::::.:: XP_016 MAENPTAGVVQEEEEDNLEYDSDGNPIAPTKKIIDPLPPIDHSEIDYPPFEKNFYNEH 10 20 30 40 50 70 80 90 100 110 120 pF1KB4 PDLARRTAQEVETYRRSKEITVRGHNCPKPVLNFYEANFPANVMDVIARQNFTEPTAIQA ... : :.. :.. .. : : :.: .: . .: ..: : ....:.:: :: XP_016 EEITNLTPQQLIDLRHKLNLRVSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQC 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB4 QGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGPICLVLAPTRELAQQ :: :::::: ::.:.:.:::::: ... : ..:: : :: ::::: ... ::::: :: XP_016 QGVPVALSGRDMIGIAKTGSGKTAAFIWPMLIHIMDQKELEPGDGPIAVIVCPTRELCQQ 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB4 VQQVAAEYCRACRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLECGKTNLRRT .. .. .: :.:. .:::. : . :..:.:: . ::::::: .. :::.:. XP_016 IHAECKRFGKAYNLRSVAVYGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRV 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB4 TYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLKDYIHINI .:::.::::::.::::: :.:.:....:::::::..:::. :....::.:.: : :.. XP_016 SYLVFDEADRMFDMGFEYQVRSIASHVRPDRQTLLFSATFRKKIEKLARDILIDPIRVVQ 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB4 GALELSANHNILQIVDVCHD-VEKDEKLIRLMEEIMSEKENKTIVFVETKRRCDELTRKM : . ::... :::.. :. : . : : . :. : .....:: : .::. .. XP_016 GDIG-EANEDVTQIVEILHSGPSKWNWLTRRLVEFTS--SGSVLLFVTKKANAEELANNL 300 310 320 330 340 350 370 380 390 400 410 420 pF1KB4 RRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKFVINYDYPNS ...: .::: .:.::. :...::. :.:.:::::.::::. ..: ::::: . XP_016 KQEGHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARD 360 370 380 390 400 410 430 440 450 460 470 480 pF1KB4 SEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVSDLISVLREANQAINPKLLQL-VEDRGS . . ::::::.:. . :.:::..::.. . ..::. :. ::: .. .::.: ... XP_016 IDTHTHRIGRTGRAGEKGVAYTLLTPKDSNFAGDLVRNLEGANQHVSKELLDLAMQNAWF 420 430 440 450 460 470 490 500 510 520 530 pF1KB4 GRSRGRGGMKDDRRDRYSAGKRGGFNTFRDR-----ENYDRGYSSLLKRDFGAKTQNGVY .:: .:: . . . : :: .:.: ::.::: ..... . : ..:.. XP_016 RKSRFKGG----KGKKLNIG--GGGLGYRERPGLGSENMDRGNNNVMSNYEAYKPSTGAM 480 490 500 510 520 540 550 560 570 580 590 pF1KB4 SAA-NYTNGSFGSNFVSAGIQTSFRTGNPTGTYQNGYDSTQQYGS--NVPNMHNGMNQQA . . ...: :.. : . .:. ... .:. : .. . :: .::. ..... XP_016 GDRLTAMKAAFQSQYKSHFVAASL-SNQKAGSSAAGASGWTSAGSLNSVPTNSAQQGHNS 530 540 550 560 570 580 600 610 pF1KB4 YAYPATAAAPMIGYPMPTGYSQ :.:.:: : : XP_016 PDSPVTSAAK--GIPGFGNTGNISGAPVTYPSAGAQGVNNTASGNNSREGTGGSNGKRER 590 600 610 620 630 640 >>NP_031398 (OMIM: 613369) ATP-dependent RNA helicase DD (938 aa) initn: 1147 init1: 790 opt: 1231 Z-score: 1279.1 bits: 247.4 E(85289): 1.7e-64 Smith-Waterman score: 1231; 37.3% identity (67.9% similar) in 585 aa overlap (37-607:192-764) 10 20 30 40 50 60 pF1KB4 DRDRGRDRGFGAPRFGGSRAGPLSGKKFGNPGEKLVKKKWNLD----ELPKFEKNFYQEH : .:.. .: . : ::::::.:: NP_031 RYMAENPTAGVVQEEEEDNLEYDSDGNPIAPTKKIIDPLPPIDHSEIDYPPFEKNFYNEH 170 180 190 200 210 220 70 80 90 100 110 120 pF1KB4 PDLARRTAQEVETYRRSKEITVRGHNCPKPVLNFYEANFPANVMDVIARQNFTEPTAIQA ... : :.. :.. .. : : :.: .: . .: ..: : ....:.:: :: NP_031 EEITNLTPQQLIDLRHKLNLRVSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQC 230 240 250 260 270 280 130 140 150 160 170 180 pF1KB4 QGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGPICLVLAPTRELAQQ :: :::::: ::.:.:.:::::: ... : ..:: : :: ::::: ... ::::: :: NP_031 QGVPVALSGRDMIGIAKTGSGKTAAFIWPMLIHIMDQKELEPGDGPIAVIVCPTRELCQQ 290 300 310 320 330 340 190 200 210 220 230 240 pF1KB4 VQQVAAEYCRACRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLECGKTNLRRT .. .. .: :.:. .:::. : . :..:.:: . ::::::: .. :::.:. NP_031 IHAECKRFGKAYNLRSVAVYGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRV 350 360 370 380 390 400 250 260 270 280 290 300 pF1KB4 TYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLKDYIHINI .:::.::::::.::::: :.:.:....:::::::..:::. :....::.:.: : :.. NP_031 SYLVFDEADRMFDMGFEYQVRSIASHVRPDRQTLLFSATFRKKIEKLARDILIDPIRVVQ 410 420 430 440 450 460 310 320 330 340 350 360 pF1KB4 GALELSANHNILQIVDVCHD-VEKDEKLIRLMEEIMSEKENKTIVFVETKRRCDELTRKM : . ::... :::.. :. : . : : . :. : .....:: : .::. .. NP_031 GDIG-EANEDVTQIVEILHSGPSKWNWLTRRLVEFTS--SGSVLLFVTKKANAEELANNL 470 480 490 500 510 370 380 390 400 410 420 pF1KB4 RRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKFVINYDYPNS ...: .::: .:.::. :...::. :.:.:::::.::::. ..: ::::: . NP_031 KQEGHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARD 520 530 540 550 560 570 430 440 450 460 470 480 pF1KB4 SEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVSDLISVLREANQAINPKLLQL-VEDRGS . . ::::::.:. . :.:::..::.. . ..::. :. ::: .. .::.: ... NP_031 IDTHTHRIGRTGRAGEKGVAYTLLTPKDSNFAGDLVRNLEGANQHVSKELLDLAMQNAWF 580 590 600 610 620 630 490 500 510 520 530 pF1KB4 GRSRGRGGMKDDRRDRYSAGKRGGFNTFRDR-----ENYDRGYSSLLKRDFGAKTQNGVY .:: .:: . . . : :: .:.: ::.::: ..... . : ..:.. NP_031 RKSRFKGG----KGKKLNIG--GGGLGYRERPGLGSENMDRGNNNVMSNYEAYKPSTGAM 640 650 660 670 680 690 540 550 560 570 580 590 pF1KB4 SAA-NYTNGSFGSNFVSAGIQTSFRTGNPTGTYQNGYDSTQQYGS--NVPNMHNGMNQQA . . ...: :.. : . .:. ... .:. : .. . :: .::. ..... NP_031 GDRLTAMKAAFQSQYKSHFVAASL-SNQKAGSSAAGASGWTSAGSLNSVPTNSAQQGHNS 700 710 720 730 740 750 600 610 pF1KB4 YAYPATAAAPMIGYPMPTGYSQ :.:.:: : : NP_031 PDSPVTSAAK--GIPGFGNTGNISGAPVTYPSAGAQGVNNTASGNNSREGTGGSNGKRER 760 770 780 790 800 >>XP_006721720 (OMIM: 613369) PREDICTED: ATP-dependent R (938 aa) initn: 1147 init1: 790 opt: 1231 Z-score: 1279.1 bits: 247.4 E(85289): 1.7e-64 Smith-Waterman score: 1231; 37.3% identity (67.9% similar) in 585 aa overlap (37-607:192-764) 10 20 30 40 50 60 pF1KB4 DRDRGRDRGFGAPRFGGSRAGPLSGKKFGNPGEKLVKKKWNLD----ELPKFEKNFYQEH : .:.. .: . : ::::::.:: XP_006 RYMAENPTAGVVQEEEEDNLEYDSDGNPIAPTKKIIDPLPPIDHSEIDYPPFEKNFYNEH 170 180 190 200 210 220 70 80 90 100 110 120 pF1KB4 PDLARRTAQEVETYRRSKEITVRGHNCPKPVLNFYEANFPANVMDVIARQNFTEPTAIQA ... : :.. :.. .. : : :.: .: . .: ..: : ....:.:: :: XP_006 EEITNLTPQQLIDLRHKLNLRVSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQC 230 240 250 260 270 280 130 140 150 160 170 180 pF1KB4 QGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGPICLVLAPTRELAQQ :: :::::: ::.:.:.:::::: ... : ..:: : :: ::::: ... ::::: :: XP_006 QGVPVALSGRDMIGIAKTGSGKTAAFIWPMLIHIMDQKELEPGDGPIAVIVCPTRELCQQ 290 300 310 320 330 340 190 200 210 220 230 240 pF1KB4 VQQVAAEYCRACRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLECGKTNLRRT .. .. .: :.:. .:::. : . :..:.:: . ::::::: .. :::.:. XP_006 IHAECKRFGKAYNLRSVAVYGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRV 350 360 370 380 390 400 250 260 270 280 290 300 pF1KB4 TYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLKDYIHINI .:::.::::::.::::: :.:.:....:::::::..:::. :....::.:.: : :.. XP_006 SYLVFDEADRMFDMGFEYQVRSIASHVRPDRQTLLFSATFRKKIEKLARDILIDPIRVVQ 410 420 430 440 450 460 310 320 330 340 350 360 pF1KB4 GALELSANHNILQIVDVCHD-VEKDEKLIRLMEEIMSEKENKTIVFVETKRRCDELTRKM : . ::... :::.. :. : . : : . :. : .....:: : .::. .. XP_006 GDIG-EANEDVTQIVEILHSGPSKWNWLTRRLVEFTS--SGSVLLFVTKKANAEELANNL 470 480 490 500 510 370 380 390 400 410 420 pF1KB4 RRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKFVINYDYPNS ...: .::: .:.::. :...::. :.:.:::::.::::. ..: ::::: . XP_006 KQEGHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARD 520 530 540 550 560 570 430 440 450 460 470 480 pF1KB4 SEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVSDLISVLREANQAINPKLLQL-VEDRGS . . ::::::.:. . :.:::..::.. . ..::. :. ::: .. .::.: ... XP_006 IDTHTHRIGRTGRAGEKGVAYTLLTPKDSNFAGDLVRNLEGANQHVSKELLDLAMQNAWF 580 590 600 610 620 630 490 500 510 520 530 pF1KB4 GRSRGRGGMKDDRRDRYSAGKRGGFNTFRDR-----ENYDRGYSSLLKRDFGAKTQNGVY .:: .:: . . . : :: .:.: ::.::: ..... . : ..:.. XP_006 RKSRFKGG----KGKKLNIG--GGGLGYRERPGLGSENMDRGNNNVMSNYEAYKPSTGAM 640 650 660 670 680 690 540 550 560 570 580 590 pF1KB4 SAA-NYTNGSFGSNFVSAGIQTSFRTGNPTGTYQNGYDSTQQYGS--NVPNMHNGMNQQA . . ...: :.. : . .:. ... .:. : .. . :: .::. ..... XP_006 GDRLTAMKAAFQSQYKSHFVAASL-SNQKAGSSAAGASGWTSAGSLNSVPTNSAQQGHNS 700 710 720 730 740 750 600 610 pF1KB4 YAYPATAAAPMIGYPMPTGYSQ :.:.:: : : XP_006 PDSPVTSAAK--GIPGFGNTGNISGAPVTYPSAGAQGVNNTASGNNSREGTGGSNGKRER 760 770 780 790 800 >>NP_987095 (OMIM: 613369) ATP-dependent RNA helicase DD (938 aa) initn: 1147 init1: 790 opt: 1231 Z-score: 1279.1 bits: 247.4 E(85289): 1.7e-64 Smith-Waterman score: 1231; 37.3% identity (67.9% similar) in 585 aa overlap (37-607:192-764) 10 20 30 40 50 60 pF1KB4 DRDRGRDRGFGAPRFGGSRAGPLSGKKFGNPGEKLVKKKWNLD----ELPKFEKNFYQEH : .:.. .: . : ::::::.:: NP_987 RYMAENPTAGVVQEEEEDNLEYDSDGNPIAPTKKIIDPLPPIDHSEIDYPPFEKNFYNEH 170 180 190 200 210 220 70 80 90 100 110 120 pF1KB4 PDLARRTAQEVETYRRSKEITVRGHNCPKPVLNFYEANFPANVMDVIARQNFTEPTAIQA ... : :.. :.. .. : : :.: .: . .: ..: : ....:.:: :: NP_987 EEITNLTPQQLIDLRHKLNLRVSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQC 230 240 250 260 270 280 130 140 150 160 170 180 pF1KB4 QGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGPICLVLAPTRELAQQ :: :::::: ::.:.:.:::::: ... : ..:: : :: ::::: ... ::::: :: NP_987 QGVPVALSGRDMIGIAKTGSGKTAAFIWPMLIHIMDQKELEPGDGPIAVIVCPTRELCQQ 290 300 310 320 330 340 190 200 210 220 230 240 pF1KB4 VQQVAAEYCRACRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLECGKTNLRRT .. .. .: :.:. .:::. : . :..:.:: . ::::::: .. :::.:. NP_987 IHAECKRFGKAYNLRSVAVYGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKKKATNLQRV 350 360 370 380 390 400 250 260 270 280 290 300 pF1KB4 TYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLKDYIHINI .:::.::::::.::::: :.:.:....:::::::..:::. :....::.:.: : :.. NP_987 SYLVFDEADRMFDMGFEYQVRSIASHVRPDRQTLLFSATFRKKIEKLARDILIDPIRVVQ 410 420 430 440 450 460 310 320 330 340 350 360 pF1KB4 GALELSANHNILQIVDVCHD-VEKDEKLIRLMEEIMSEKENKTIVFVETKRRCDELTRKM : . ::... :::.. :. : . : : . :. : .....:: : .::. .. NP_987 GDIG-EANEDVTQIVEILHSGPSKWNWLTRRLVEFTS--SGSVLLFVTKKANAEELANNL 470 480 490 500 510 370 380 390 400 410 420 pF1KB4 RRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKFVINYDYPNS ...: .::: .:.::. :...::. :.:.:::::.::::. ..: ::::: . NP_987 KQEGHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARD 520 530 540 550 560 570 430 440 450 460 470 480 pF1KB4 SEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVSDLISVLREANQAINPKLLQL-VEDRGS . . ::::::.:. . :.:::..::.. . ..::. :. ::: .. .::.: ... NP_987 IDTHTHRIGRTGRAGEKGVAYTLLTPKDSNFAGDLVRNLEGANQHVSKELLDLAMQNAWF 580 590 600 610 620 630 490 500 510 520 530 pF1KB4 GRSRGRGGMKDDRRDRYSAGKRGGFNTFRDR-----ENYDRGYSSLLKRDFGAKTQNGVY .:: .:: . . . : :: .:.: ::.::: ..... . : ..:.. NP_987 RKSRFKGG----KGKKLNIG--GGGLGYRERPGLGSENMDRGNNNVMSNYEAYKPSTGAM 640 650 660 670 680 690 540 550 560 570 580 590 pF1KB4 SAA-NYTNGSFGSNFVSAGIQTSFRTGNPTGTYQNGYDSTQQYGS--NVPNMHNGMNQQA . . ...: :.. : . .:. ... .:. : .. . :: .::. ..... NP_987 GDRLTAMKAAFQSQYKSHFVAASL-SNQKAGSSAAGASGWTSAGSLNSVPTNSAQQGHNS 700 710 720 730 740 750 600 610 pF1KB4 YAYPATAAAPMIGYPMPTGYSQ :.:.:: : : NP_987 PDSPVTSAAK--GIPGFGNTGNISGAPVTYPSAGAQGVNNTASGNNSREGTGGSNGKRER 760 770 780 790 800 614 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 14:26:45 2016 done: Thu Nov 3 14:26:46 2016 Total Scan time: 10.570 Total Display time: 0.160 Function used was FASTA [36.3.4 Apr, 2011]