FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB4123, 468 aa
1>>>pF1KB4123 468 - 468 aa - 468 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.5683+/-0.000554; mu= 11.8820+/- 0.034
mean_var=172.0384+/-40.379, 0's: 0 Z-trim(112.3): 543 B-trim: 2185 in 2/48
Lambda= 0.097783
statistics sampled from 20437 (21143) to 20437 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.608), E-opt: 0.2 (0.248), width: 16
Scan time: 7.730
The best scores are: opt bits E(85289)
NP_004058 (OMIM: 602857) beta-chimaerin isoform 2 ( 468) 3145 456.9 5.5e-128
NP_001279998 (OMIM: 602857) beta-chimaerin isoform ( 543) 3074 446.9 6.2e-125
XP_011513409 (OMIM: 602857) PREDICTED: beta-chimae ( 494) 3062 445.2 1.9e-124
XP_011513407 (OMIM: 602857) PREDICTED: beta-chimae ( 569) 3062 445.3 2.1e-124
NP_001280001 (OMIM: 602857) beta-chimaerin isoform ( 453) 3058 444.6 2.6e-124
XP_016867211 (OMIM: 602857) PREDICTED: beta-chimae ( 500) 3058 444.6 2.8e-124
XP_016867210 (OMIM: 602857) PREDICTED: beta-chimae ( 575) 3058 444.7 3.1e-124
NP_001279999 (OMIM: 602857) beta-chimaerin isoform ( 481) 3050 443.5 6e-124
XP_011513408 (OMIM: 602857) PREDICTED: beta-chimae ( 556) 3050 443.6 6.6e-124
NP_001280000 (OMIM: 602857) beta-chimaerin isoform ( 433) 2823 411.4 2.5e-114
NP_001813 (OMIM: 118423,604356) N-chimaerin isofor ( 459) 2319 340.3 6.4e-93
NP_001035025 (OMIM: 602857) beta-chimaerin isoform ( 332) 1885 279.0 1.4e-74
NP_001280002 (OMIM: 602857) beta-chimaerin isoform ( 287) 1715 254.9 2.1e-67
NP_001280010 (OMIM: 602857) beta-chimaerin isoform ( 261) 1708 253.9 4e-67
NP_001193531 (OMIM: 118423,604356) N-chimaerin iso ( 334) 1503 225.1 2.4e-58
NP_001020372 (OMIM: 118423,604356) N-chimaerin iso ( 433) 1409 211.9 2.7e-54
NP_001280005 (OMIM: 602857) beta-chimaerin isoform ( 274) 1065 163.2 8.3e-40
NP_001280009 (OMIM: 602857) beta-chimaerin isoform ( 286) 1007 155.0 2.5e-37
NP_001280008 (OMIM: 602857) beta-chimaerin isoform ( 197) 994 153.0 6.9e-37
NP_001280004 (OMIM: 602857) beta-chimaerin isoform ( 241) 837 130.9 3.7e-30
NP_001280006 (OMIM: 602857) beta-chimaerin isoform ( 260) 824 129.2 1.4e-29
NP_001280007 (OMIM: 602857) beta-chimaerin isoform ( 228) 589 95.9 1.2e-19
NP_001123537 (OMIM: 602129,609753) unconventional (2022) 463 79.3 1.1e-13
NP_004136 (OMIM: 602129,609753) unconventional myo (2157) 463 79.3 1.1e-13
XP_011519925 (OMIM: 604875) PREDICTED: unconventio (1737) 458 78.5 1.6e-13
XP_016877719 (OMIM: 604875) PREDICTED: unconventio (2547) 458 78.7 2.1e-13
NP_008832 (OMIM: 604875) unconventional myosin-IXa (2548) 458 78.7 2.1e-13
XP_011519924 (OMIM: 604875) PREDICTED: unconventio (2566) 458 78.7 2.1e-13
XP_016877718 (OMIM: 604875) PREDICTED: unconventio (2566) 458 78.7 2.1e-13
XP_011519923 (OMIM: 604875) PREDICTED: unconventio (2598) 458 78.7 2.1e-13
XP_011519922 (OMIM: 604875) PREDICTED: unconventio (2618) 458 78.7 2.1e-13
XP_006720602 (OMIM: 604875) PREDICTED: unconventio (2619) 458 78.7 2.1e-13
XP_016877717 (OMIM: 604875) PREDICTED: unconventio (2619) 458 78.7 2.1e-13
XP_011519921 (OMIM: 604875) PREDICTED: unconventio (2619) 458 78.7 2.1e-13
XP_011519920 (OMIM: 604875) PREDICTED: unconventio (2620) 458 78.7 2.1e-13
XP_011519919 (OMIM: 604875) PREDICTED: unconventio (2637) 458 78.7 2.1e-13
XP_011519918 (OMIM: 604875) PREDICTED: unconventio (2638) 458 78.7 2.1e-13
XP_011519915 (OMIM: 604875) PREDICTED: unconventio (2638) 458 78.7 2.1e-13
XP_011519916 (OMIM: 604875) PREDICTED: unconventio (2638) 458 78.7 2.1e-13
XP_011519917 (OMIM: 604875) PREDICTED: unconventio (2638) 458 78.7 2.1e-13
XP_011509785 (OMIM: 610578) PREDICTED: rho GTPase- ( 397) 442 75.5 3e-13
XP_016859989 (OMIM: 610578) PREDICTED: rho GTPase- ( 432) 442 75.5 3.2e-13
NP_954976 (OMIM: 610591) rho GTPase-activating pro ( 548) 443 75.8 3.4e-13
XP_011509781 (OMIM: 610578) PREDICTED: rho GTPase- ( 475) 442 75.6 3.4e-13
NP_060930 (OMIM: 610578) rho GTPase-activating pro ( 475) 442 75.6 3.4e-13
XP_016859988 (OMIM: 610578) PREDICTED: rho GTPase- ( 475) 442 75.6 3.4e-13
XP_011522776 (OMIM: 610591) PREDICTED: rho GTPase- ( 581) 443 75.8 3.5e-13
XP_005257185 (OMIM: 610591) PREDICTED: rho GTPase- ( 667) 443 75.9 3.8e-13
XP_016879801 (OMIM: 610591) PREDICTED: rho GTPase- ( 689) 443 75.9 3.9e-13
XP_011522774 (OMIM: 610591) PREDICTED: rho GTPase- ( 722) 443 75.9 4e-13
>>NP_004058 (OMIM: 602857) beta-chimaerin isoform 2 [Hom (468 aa)
initn: 3145 init1: 3145 opt: 3145 Z-score: 2418.8 bits: 456.9 E(85289): 5.5e-128
Smith-Waterman score: 3145; 100.0% identity (100.0% similar) in 468 aa overlap (1-468:1-468)
10 20 30 40 50 60
pF1KB4 MAASSNSSLSGSSVSSDAEEYQPPIWKSYLYQLQQEAPRPKRIICPREVENRPKYYGREF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MAASSNSSLSGSSVSSDAEEYQPPIWKSYLYQLQQEAPRPKRIICPREVENRPKYYGREF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 HGIISREQADELLGGVEGAYILRESQRQPGCYTLALRFGNQTLNYRLFHDGKHFVGEKRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 HGIISREQADELLGGVEGAYILRESQRQPGCYTLALRFGNQTLNYRLFHDGKHFVGEKRF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 ESIHDLVTDGLITLYIETKAAEYISKMTTNPIYEHIGYATLLREKVSRRLSRSKNEPRKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ESIHDLVTDGLITLYIETKAAEYISKMTTNPIYEHIGYATLLREKVSRRLSRSKNEPRKT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 NVTHEEHTAVEKISSLVRRAALTHNDNHFNYEKTHNFKVHTFRGPHWCEYCANFMWGLIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 NVTHEEHTAVEKISSLVRRAALTHNDNHFNYEKTHNFKVHTFRGPHWCEYCANFMWGLIA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 QGVRCSDCGLNVHKQCSKHVPNDCQPDLKRIKKVYCCDLTTLVKAHNTQRPMVVDICIRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 QGVRCSDCGLNVHKQCSKHVPNDCQPDLKRIKKVYCCDLTTLVKAHNTQRPMVVDICIRE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 IEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEKADISANVYPDINIITGALKLYFRDLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 IEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEKADISANVYPDINIITGALKLYFRDLP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 IPVITYDTYSKFIDAAKISNADERLEAVHEVLMLLPPAHYETLRYLMIHLKKVTMNEKDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 IPVITYDTYSKFIDAAKISNADERLEAVHEVLMLLPPAHYETLRYLMIHLKKVTMNEKDN
370 380 390 400 410 420
430 440 450 460
pF1KB4 FMNAENLGIVFGPTLMRPPEDSTLTTLHDMRYQKLIVQILIENEDVLF
::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 FMNAENLGIVFGPTLMRPPEDSTLTTLHDMRYQKLIVQILIENEDVLF
430 440 450 460
>>NP_001279998 (OMIM: 602857) beta-chimaerin isoform 3 [ (543 aa)
initn: 3074 init1: 3074 opt: 3074 Z-score: 2363.9 bits: 446.9 E(85289): 6.2e-125
Smith-Waterman score: 3074; 99.6% identity (99.8% similar) in 457 aa overlap (12-468:87-543)
10 20 30 40
pF1KB4 MAASSNSSLSGSSVSSDAEEYQPPIWKSYLYQLQQEAPRPK
:: .::::::::::::::::::::::::::
NP_001 LASPGFTFGKRVVFDSHCLKRQHTFADGLHSSCTSDAEEYQPPIWKSYLYQLQQEAPRPK
60 70 80 90 100 110
50 60 70 80 90 100
pF1KB4 RIICPREVENRPKYYGREFHGIISREQADELLGGVEGAYILRESQRQPGCYTLALRFGNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RIICPREVENRPKYYGREFHGIISREQADELLGGVEGAYILRESQRQPGCYTLALRFGNQ
120 130 140 150 160 170
110 120 130 140 150 160
pF1KB4 TLNYRLFHDGKHFVGEKRFESIHDLVTDGLITLYIETKAAEYISKMTTNPIYEHIGYATL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLNYRLFHDGKHFVGEKRFESIHDLVTDGLITLYIETKAAEYISKMTTNPIYEHIGYATL
180 190 200 210 220 230
170 180 190 200 210 220
pF1KB4 LREKVSRRLSRSKNEPRKTNVTHEEHTAVEKISSLVRRAALTHNDNHFNYEKTHNFKVHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LREKVSRRLSRSKNEPRKTNVTHEEHTAVEKISSLVRRAALTHNDNHFNYEKTHNFKVHT
240 250 260 270 280 290
230 240 250 260 270 280
pF1KB4 FRGPHWCEYCANFMWGLIAQGVRCSDCGLNVHKQCSKHVPNDCQPDLKRIKKVYCCDLTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FRGPHWCEYCANFMWGLIAQGVRCSDCGLNVHKQCSKHVPNDCQPDLKRIKKVYCCDLTT
300 310 320 330 340 350
290 300 310 320 330 340
pF1KB4 LVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEKADISANV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEKADISANV
360 370 380 390 400 410
350 360 370 380 390 400
pF1KB4 YPDINIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVLMLLPPAHYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YPDINIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVLMLLPPAHYE
420 430 440 450 460 470
410 420 430 440 450 460
pF1KB4 TLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDSTLTTLHDMRYQKLIVQILI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDSTLTTLHDMRYQKLIVQILI
480 490 500 510 520 530
pF1KB4 ENEDVLF
:::::::
NP_001 ENEDVLF
540
>>XP_011513409 (OMIM: 602857) PREDICTED: beta-chimaerin (494 aa)
initn: 3060 init1: 3060 opt: 3062 Z-score: 2355.2 bits: 445.2 E(85289): 1.9e-124
Smith-Waterman score: 3083; 94.7% identity (94.7% similar) in 494 aa overlap (1-468:1-494)
10 20 30
pF1KB4 MAASSNSSLSGSSVSS--------------------------DAEEYQPPIWKSYLYQLQ
:::::::::::::::: ::::::::::::::::::
XP_011 MAASSNSSLSGSSVSSVYSEPRSPRELPKSPDTQASLQFPQTDAEEYQPPIWKSYLYQLQ
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB4 QEAPRPKRIICPREVENRPKYYGREFHGIISREQADELLGGVEGAYILRESQRQPGCYTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QEAPRPKRIICPREVENRPKYYGREFHGIISREQADELLGGVEGAYILRESQRQPGCYTL
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB4 ALRFGNQTLNYRLFHDGKHFVGEKRFESIHDLVTDGLITLYIETKAAEYISKMTTNPIYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALRFGNQTLNYRLFHDGKHFVGEKRFESIHDLVTDGLITLYIETKAAEYISKMTTNPIYE
130 140 150 160 170 180
160 170 180 190 200 210
pF1KB4 HIGYATLLREKVSRRLSRSKNEPRKTNVTHEEHTAVEKISSLVRRAALTHNDNHFNYEKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HIGYATLLREKVSRRLSRSKNEPRKTNVTHEEHTAVEKISSLVRRAALTHNDNHFNYEKT
190 200 210 220 230 240
220 230 240 250 260 270
pF1KB4 HNFKVHTFRGPHWCEYCANFMWGLIAQGVRCSDCGLNVHKQCSKHVPNDCQPDLKRIKKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HNFKVHTFRGPHWCEYCANFMWGLIAQGVRCSDCGLNVHKQCSKHVPNDCQPDLKRIKKV
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB4 YCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEK
310 320 330 340 350 360
340 350 360 370 380 390
pF1KB4 ADISANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVLML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ADISANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVLML
370 380 390 400 410 420
400 410 420 430 440 450
pF1KB4 LPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDSTLTTLHDMRYQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDSTLTTLHDMRYQK
430 440 450 460 470 480
460
pF1KB4 LIVQILIENEDVLF
::::::::::::::
XP_011 LIVQILIENEDVLF
490
>>XP_011513407 (OMIM: 602857) PREDICTED: beta-chimaerin (569 aa)
initn: 3060 init1: 3060 opt: 3062 Z-score: 2354.5 bits: 445.3 E(85289): 2.1e-124
Smith-Waterman score: 3062; 97.0% identity (98.5% similar) in 468 aa overlap (1-468:102-569)
10 20 30
pF1KB4 MAASSNSSLSGSSVSSDAEEYQPPIWKSYL
. : ... : . ..::::::::::::::
XP_011 SHCLKRQHTFADGLHSSCTSIYSEPRSPRELPKSPDTQASLQFPQTDAEEYQPPIWKSYL
80 90 100 110 120 130
40 50 60 70 80 90
pF1KB4 YQLQQEAPRPKRIICPREVENRPKYYGREFHGIISREQADELLGGVEGAYILRESQRQPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YQLQQEAPRPKRIICPREVENRPKYYGREFHGIISREQADELLGGVEGAYILRESQRQPG
140 150 160 170 180 190
100 110 120 130 140 150
pF1KB4 CYTLALRFGNQTLNYRLFHDGKHFVGEKRFESIHDLVTDGLITLYIETKAAEYISKMTTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CYTLALRFGNQTLNYRLFHDGKHFVGEKRFESIHDLVTDGLITLYIETKAAEYISKMTTN
200 210 220 230 240 250
160 170 180 190 200 210
pF1KB4 PIYEHIGYATLLREKVSRRLSRSKNEPRKTNVTHEEHTAVEKISSLVRRAALTHNDNHFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PIYEHIGYATLLREKVSRRLSRSKNEPRKTNVTHEEHTAVEKISSLVRRAALTHNDNHFN
260 270 280 290 300 310
220 230 240 250 260 270
pF1KB4 YEKTHNFKVHTFRGPHWCEYCANFMWGLIAQGVRCSDCGLNVHKQCSKHVPNDCQPDLKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YEKTHNFKVHTFRGPHWCEYCANFMWGLIAQGVRCSDCGLNVHKQCSKHVPNDCQPDLKR
320 330 340 350 360 370
280 290 300 310 320 330
pF1KB4 IKKVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IKKVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDR
380 390 400 410 420 430
340 350 360 370 380 390
pF1KB4 DGEKADISANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DGEKADISANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHE
440 450 460 470 480 490
400 410 420 430 440 450
pF1KB4 VLMLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDSTLTTLHDM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLMLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDSTLTTLHDM
500 510 520 530 540 550
460
pF1KB4 RYQKLIVQILIENEDVLF
::::::::::::::::::
XP_011 RYQKLIVQILIENEDVLF
560
>>NP_001280001 (OMIM: 602857) beta-chimaerin isoform 6 [ (453 aa)
initn: 3058 init1: 3058 opt: 3058 Z-score: 2352.6 bits: 444.6 E(85289): 2.6e-124
Smith-Waterman score: 3058; 100.0% identity (100.0% similar) in 452 aa overlap (17-468:2-453)
10 20 30 40 50 60
pF1KB4 MAASSNSSLSGSSVSSDAEEYQPPIWKSYLYQLQQEAPRPKRIICPREVENRPKYYGREF
::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDAEEYQPPIWKSYLYQLQQEAPRPKRIICPREVENRPKYYGREF
10 20 30 40
70 80 90 100 110 120
pF1KB4 HGIISREQADELLGGVEGAYILRESQRQPGCYTLALRFGNQTLNYRLFHDGKHFVGEKRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HGIISREQADELLGGVEGAYILRESQRQPGCYTLALRFGNQTLNYRLFHDGKHFVGEKRF
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB4 ESIHDLVTDGLITLYIETKAAEYISKMTTNPIYEHIGYATLLREKVSRRLSRSKNEPRKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESIHDLVTDGLITLYIETKAAEYISKMTTNPIYEHIGYATLLREKVSRRLSRSKNEPRKT
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB4 NVTHEEHTAVEKISSLVRRAALTHNDNHFNYEKTHNFKVHTFRGPHWCEYCANFMWGLIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NVTHEEHTAVEKISSLVRRAALTHNDNHFNYEKTHNFKVHTFRGPHWCEYCANFMWGLIA
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB4 QGVRCSDCGLNVHKQCSKHVPNDCQPDLKRIKKVYCCDLTTLVKAHNTQRPMVVDICIRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QGVRCSDCGLNVHKQCSKHVPNDCQPDLKRIKKVYCCDLTTLVKAHNTQRPMVVDICIRE
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB4 IEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEKADISANVYPDINIITGALKLYFRDLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEKADISANVYPDINIITGALKLYFRDLP
290 300 310 320 330 340
370 380 390 400 410 420
pF1KB4 IPVITYDTYSKFIDAAKISNADERLEAVHEVLMLLPPAHYETLRYLMIHLKKVTMNEKDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IPVITYDTYSKFIDAAKISNADERLEAVHEVLMLLPPAHYETLRYLMIHLKKVTMNEKDN
350 360 370 380 390 400
430 440 450 460
pF1KB4 FMNAENLGIVFGPTLMRPPEDSTLTTLHDMRYQKLIVQILIENEDVLF
::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FMNAENLGIVFGPTLMRPPEDSTLTTLHDMRYQKLIVQILIENEDVLF
410 420 430 440 450
>>XP_016867211 (OMIM: 602857) PREDICTED: beta-chimaerin (500 aa)
initn: 3131 init1: 3058 opt: 3058 Z-score: 2352.1 bits: 444.6 E(85289): 2.8e-124
Smith-Waterman score: 3071; 93.6% identity (93.6% similar) in 500 aa overlap (1-468:1-500)
10 20
pF1KB4 MAASSNSSLSGSSVSS--------------------------------DAEEYQPPIWKS
:::::::::::::::: ::::::::::::
XP_016 MAASSNSSLSGSSVSSVYSEPRSPRELPKSPDTQASLQFPQTDYKLLEDAEEYQPPIWKS
10 20 30 40 50 60
30 40 50 60 70 80
pF1KB4 YLYQLQQEAPRPKRIICPREVENRPKYYGREFHGIISREQADELLGGVEGAYILRESQRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YLYQLQQEAPRPKRIICPREVENRPKYYGREFHGIISREQADELLGGVEGAYILRESQRQ
70 80 90 100 110 120
90 100 110 120 130 140
pF1KB4 PGCYTLALRFGNQTLNYRLFHDGKHFVGEKRFESIHDLVTDGLITLYIETKAAEYISKMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGCYTLALRFGNQTLNYRLFHDGKHFVGEKRFESIHDLVTDGLITLYIETKAAEYISKMT
130 140 150 160 170 180
150 160 170 180 190 200
pF1KB4 TNPIYEHIGYATLLREKVSRRLSRSKNEPRKTNVTHEEHTAVEKISSLVRRAALTHNDNH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TNPIYEHIGYATLLREKVSRRLSRSKNEPRKTNVTHEEHTAVEKISSLVRRAALTHNDNH
190 200 210 220 230 240
210 220 230 240 250 260
pF1KB4 FNYEKTHNFKVHTFRGPHWCEYCANFMWGLIAQGVRCSDCGLNVHKQCSKHVPNDCQPDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FNYEKTHNFKVHTFRGPHWCEYCANFMWGLIAQGVRCSDCGLNVHKQCSKHVPNDCQPDL
250 260 270 280 290 300
270 280 290 300 310 320
pF1KB4 KRIKKVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KRIKKVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAF
310 320 330 340 350 360
330 340 350 360 370 380
pF1KB4 DRDGEKADISANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DRDGEKADISANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAV
370 380 390 400 410 420
390 400 410 420 430 440
pF1KB4 HEVLMLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDSTLTTLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HEVLMLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDSTLTTLH
430 440 450 460 470 480
450 460
pF1KB4 DMRYQKLIVQILIENEDVLF
::::::::::::::::::::
XP_016 DMRYQKLIVQILIENEDVLF
490 500
>>XP_016867210 (OMIM: 602857) PREDICTED: beta-chimaerin (575 aa)
initn: 3058 init1: 3058 opt: 3058 Z-score: 2351.4 bits: 444.7 E(85289): 3.1e-124
Smith-Waterman score: 3058; 100.0% identity (100.0% similar) in 452 aa overlap (17-468:124-575)
10 20 30 40
pF1KB4 MAASSNSSLSGSSVSSDAEEYQPPIWKSYLYQLQQEAPRPKRIICP
::::::::::::::::::::::::::::::
XP_016 SEPRSPRELPKSPDTQASLQFPQTDYKLLEDAEEYQPPIWKSYLYQLQQEAPRPKRIICP
100 110 120 130 140 150
50 60 70 80 90 100
pF1KB4 REVENRPKYYGREFHGIISREQADELLGGVEGAYILRESQRQPGCYTLALRFGNQTLNYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 REVENRPKYYGREFHGIISREQADELLGGVEGAYILRESQRQPGCYTLALRFGNQTLNYR
160 170 180 190 200 210
110 120 130 140 150 160
pF1KB4 LFHDGKHFVGEKRFESIHDLVTDGLITLYIETKAAEYISKMTTNPIYEHIGYATLLREKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFHDGKHFVGEKRFESIHDLVTDGLITLYIETKAAEYISKMTTNPIYEHIGYATLLREKV
220 230 240 250 260 270
170 180 190 200 210 220
pF1KB4 SRRLSRSKNEPRKTNVTHEEHTAVEKISSLVRRAALTHNDNHFNYEKTHNFKVHTFRGPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SRRLSRSKNEPRKTNVTHEEHTAVEKISSLVRRAALTHNDNHFNYEKTHNFKVHTFRGPH
280 290 300 310 320 330
230 240 250 260 270 280
pF1KB4 WCEYCANFMWGLIAQGVRCSDCGLNVHKQCSKHVPNDCQPDLKRIKKVYCCDLTTLVKAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WCEYCANFMWGLIAQGVRCSDCGLNVHKQCSKHVPNDCQPDLKRIKKVYCCDLTTLVKAH
340 350 360 370 380 390
290 300 310 320 330 340
pF1KB4 NTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEKADISANVYPDIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEKADISANVYPDIN
400 410 420 430 440 450
350 360 370 380 390 400
pF1KB4 IITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVLMLLPPAHYETLRYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVLMLLPPAHYETLRYL
460 470 480 490 500 510
410 420 430 440 450 460
pF1KB4 MIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDSTLTTLHDMRYQKLIVQILIENEDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDSTLTTLHDMRYQKLIVQILIENEDV
520 530 540 550 560 570
pF1KB4 LF
::
XP_016 LF
>>NP_001279999 (OMIM: 602857) beta-chimaerin isoform 4 [ (481 aa)
initn: 3050 init1: 3050 opt: 3050 Z-score: 2346.2 bits: 443.5 E(85289): 6e-124
Smith-Waterman score: 3098; 97.1% identity (97.1% similar) in 481 aa overlap (1-468:1-481)
10 20 30 40
pF1KB4 MAASSNSSLSGSSVSS-------------DAEEYQPPIWKSYLYQLQQEAPRPKRIICPR
:::::::::::::::: ::::::::::::::::::::::::::::::
NP_001 MAASSNSSLSGSSVSSVYSEPRSPRELPKYAEEYQPPIWKSYLYQLQQEAPRPKRIICPR
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB4 EVENRPKYYGREFHGIISREQADELLGGVEGAYILRESQRQPGCYTLALRFGNQTLNYRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVENRPKYYGREFHGIISREQADELLGGVEGAYILRESQRQPGCYTLALRFGNQTLNYRL
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB4 FHDGKHFVGEKRFESIHDLVTDGLITLYIETKAAEYISKMTTNPIYEHIGYATLLREKVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FHDGKHFVGEKRFESIHDLVTDGLITLYIETKAAEYISKMTTNPIYEHIGYATLLREKVS
130 140 150 160 170 180
170 180 190 200 210 220
pF1KB4 RRLSRSKNEPRKTNVTHEEHTAVEKISSLVRRAALTHNDNHFNYEKTHNFKVHTFRGPHW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RRLSRSKNEPRKTNVTHEEHTAVEKISSLVRRAALTHNDNHFNYEKTHNFKVHTFRGPHW
190 200 210 220 230 240
230 240 250 260 270 280
pF1KB4 CEYCANFMWGLIAQGVRCSDCGLNVHKQCSKHVPNDCQPDLKRIKKVYCCDLTTLVKAHN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CEYCANFMWGLIAQGVRCSDCGLNVHKQCSKHVPNDCQPDLKRIKKVYCCDLTTLVKAHN
250 260 270 280 290 300
290 300 310 320 330 340
pF1KB4 TQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEKADISANVYPDINI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEKADISANVYPDINI
310 320 330 340 350 360
350 360 370 380 390 400
pF1KB4 ITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVLMLLPPAHYETLRYLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVLMLLPPAHYETLRYLM
370 380 390 400 410 420
410 420 430 440 450 460
pF1KB4 IHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDSTLTTLHDMRYQKLIVQILIENEDVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDSTLTTLHDMRYQKLIVQILIENEDVL
430 440 450 460 470 480
pF1KB4 F
:
NP_001 F
>>XP_011513408 (OMIM: 602857) PREDICTED: beta-chimaerin (556 aa)
initn: 3050 init1: 3050 opt: 3050 Z-score: 2345.5 bits: 443.6 E(85289): 6.6e-124
Smith-Waterman score: 3050; 100.0% identity (100.0% similar) in 451 aa overlap (18-468:106-556)
10 20 30 40
pF1KB4 MAASSNSSLSGSSVSSDAEEYQPPIWKSYLYQLQQEAPRPKRIICPR
::::::::::::::::::::::::::::::
XP_011 KRQHTFADGLHSSCTSIYSEPRSPRELPKYAEEYQPPIWKSYLYQLQQEAPRPKRIICPR
80 90 100 110 120 130
50 60 70 80 90 100
pF1KB4 EVENRPKYYGREFHGIISREQADELLGGVEGAYILRESQRQPGCYTLALRFGNQTLNYRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVENRPKYYGREFHGIISREQADELLGGVEGAYILRESQRQPGCYTLALRFGNQTLNYRL
140 150 160 170 180 190
110 120 130 140 150 160
pF1KB4 FHDGKHFVGEKRFESIHDLVTDGLITLYIETKAAEYISKMTTNPIYEHIGYATLLREKVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FHDGKHFVGEKRFESIHDLVTDGLITLYIETKAAEYISKMTTNPIYEHIGYATLLREKVS
200 210 220 230 240 250
170 180 190 200 210 220
pF1KB4 RRLSRSKNEPRKTNVTHEEHTAVEKISSLVRRAALTHNDNHFNYEKTHNFKVHTFRGPHW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RRLSRSKNEPRKTNVTHEEHTAVEKISSLVRRAALTHNDNHFNYEKTHNFKVHTFRGPHW
260 270 280 290 300 310
230 240 250 260 270 280
pF1KB4 CEYCANFMWGLIAQGVRCSDCGLNVHKQCSKHVPNDCQPDLKRIKKVYCCDLTTLVKAHN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CEYCANFMWGLIAQGVRCSDCGLNVHKQCSKHVPNDCQPDLKRIKKVYCCDLTTLVKAHN
320 330 340 350 360 370
290 300 310 320 330 340
pF1KB4 TQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEKADISANVYPDINI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEKADISANVYPDINI
380 390 400 410 420 430
350 360 370 380 390 400
pF1KB4 ITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVLMLLPPAHYETLRYLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVLMLLPPAHYETLRYLM
440 450 460 470 480 490
410 420 430 440 450 460
pF1KB4 IHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDSTLTTLHDMRYQKLIVQILIENEDVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDSTLTTLHDMRYQKLIVQILIENEDVL
500 510 520 530 540 550
pF1KB4 F
:
XP_011 F
>>NP_001280000 (OMIM: 602857) beta-chimaerin isoform 5 [ (433 aa)
initn: 2823 init1: 2823 opt: 2823 Z-score: 2173.7 bits: 411.4 E(85289): 2.5e-114
Smith-Waterman score: 2823; 100.0% identity (100.0% similar) in 420 aa overlap (49-468:14-433)
20 30 40 50 60 70
pF1KB4 EEYQPPIWKSYLYQLQQEAPRPKRIICPREVENRPKYYGREFHGIISREQADELLGGVEG
::::::::::::::::::::::::::::::
NP_001 MLKNTSLLYGNHTVENRPKYYGREFHGIISREQADELLGGVEG
10 20 30 40
80 90 100 110 120 130
pF1KB4 AYILRESQRQPGCYTLALRFGNQTLNYRLFHDGKHFVGEKRFESIHDLVTDGLITLYIET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AYILRESQRQPGCYTLALRFGNQTLNYRLFHDGKHFVGEKRFESIHDLVTDGLITLYIET
50 60 70 80 90 100
140 150 160 170 180 190
pF1KB4 KAAEYISKMTTNPIYEHIGYATLLREKVSRRLSRSKNEPRKTNVTHEEHTAVEKISSLVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KAAEYISKMTTNPIYEHIGYATLLREKVSRRLSRSKNEPRKTNVTHEEHTAVEKISSLVR
110 120 130 140 150 160
200 210 220 230 240 250
pF1KB4 RAALTHNDNHFNYEKTHNFKVHTFRGPHWCEYCANFMWGLIAQGVRCSDCGLNVHKQCSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RAALTHNDNHFNYEKTHNFKVHTFRGPHWCEYCANFMWGLIAQGVRCSDCGLNVHKQCSK
170 180 190 200 210 220
260 270 280 290 300 310
pF1KB4 HVPNDCQPDLKRIKKVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HVPNDCQPDLKRIKKVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFT
230 240 250 260 270 280
320 330 340 350 360 370
pF1KB4 EHIEDVKMAFDRDGEKADISANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDAAKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EHIEDVKMAFDRDGEKADISANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDAAKI
290 300 310 320 330 340
380 390 400 410 420 430
pF1KB4 SNADERLEAVHEVLMLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SNADERLEAVHEVLMLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRP
350 360 370 380 390 400
440 450 460
pF1KB4 PEDSTLTTLHDMRYQKLIVQILIENEDVLF
::::::::::::::::::::::::::::::
NP_001 PEDSTLTTLHDMRYQKLIVQILIENEDVLF
410 420 430
468 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 05:39:22 2016 done: Sat Nov 5 05:39:23 2016
Total Scan time: 7.730 Total Display time: 0.070
Function used was FASTA [36.3.4 Apr, 2011]