FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4140, 747 aa 1>>>pF1KB4140 747 - 747 aa - 747 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.8070+/-0.000945; mu= 14.5807+/- 0.057 mean_var=136.9833+/-27.141, 0's: 0 Z-trim(110.7): 25 B-trim: 0 in 0/54 Lambda= 0.109582 statistics sampled from 11769 (11788) to 11769 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.708), E-opt: 0.2 (0.362), width: 16 Scan time: 3.820 The best scores are: opt bits E(32554) CCDS1337.1 QSOX1 gene_id:5768|Hs108|chr1 ( 747) 5083 815.6 0 CCDS30950.1 QSOX1 gene_id:5768|Hs108|chr1 ( 604) 4092 658.8 7e-189 CCDS35178.1 QSOX2 gene_id:169714|Hs108|chr9 ( 698) 1601 265.0 2.8e-70 >>CCDS1337.1 QSOX1 gene_id:5768|Hs108|chr1 (747 aa) initn: 5083 init1: 5083 opt: 5083 Z-score: 4349.9 bits: 815.6 E(32554): 0 Smith-Waterman score: 5083; 99.9% identity (100.0% similar) in 747 aa overlap (1-747:1-747) 10 20 30 40 50 60 pF1KB4 MRRCNSGSGPPPSLLLLLLWLLAVPGANAAPRSALYSPSDPLTLLQADTVRGAVLGSRSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 MRRCNSGSGPPPSLLLLLLWLLAVPGANAAPRSALYSPSDPLTLLQADTVRGAVLGSRSA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 WAVEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLAALDCAEETNSAVCRDFNIPGFPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 WAVEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLAALDCAEETNSAVCRDFNIPGFPT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 VRFFKAFTKNGSGAVFPVAGADVQTLRERLIDALESHHDTWPPACPPLEPAKLEEIDGFF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 VRFFKAFTKNGSGAVFPVAGADVQTLRERLIDALESHHDTWPPACPPLEPAKLEEIDGFF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 ARNNEEYLALIFEKGGSYLAREVALDLSQHKGVAVRRVLNTEANVVRKFGVTDFPSCYLL :::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::: CCDS13 ARNNEEYLALIFEKGGSYLGREVALDLSQHKGVAVRRVLNTEANVVRKFGVTDFPSCYLL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 FRNGSVSRVPVLMESRSFYTAYLQRLSGLTREAAQTTVAPTTANKIAPTVWKLADRSKIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 FRNGSVSRVPVLMESRSFYTAYLQRLSGLTREAAQTTVAPTTANKIAPTVWKLADRSKIY 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 MADLESALHYILRIEVGRFPVLEGQRLVALKKFVAVLAKYFPGRPLVQNFLHSVNEWLKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 MADLESALHYILRIEVGRFPVLEGQRLVALKKFVAVLAKYFPGRPLVQNFLHSVNEWLKR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 QKRNKIPYSFFKTALDDRKEGAVLAKKVNWIGCQGSEPHFRGFPCSLWVLFHFLTVQAAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 QKRNKIPYSFFKTALDDRKEGAVLAKKVNWIGCQGSEPHFRGFPCSLWVLFHFLTVQAAR 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB4 QNVDHSQEAAKAKEVLPAIRGYVHYFFGCRDCASHFEQMAAASMHRVGSPNAAVLWLWSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 QNVDHSQEAAKAKEVLPAIRGYVHYFFGCRDCASHFEQMAAASMHRVGSPNAAVLWLWSS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB4 HNRVNARLAGAPSEDPQFPKVQWPPRELCSACHNERLDVPVWDVEATLNFLKAHFSPSNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 HNRVNARLAGAPSEDPQFPKVQWPPRELCSACHNERLDVPVWDVEATLNFLKAHFSPSNI 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB4 ILDFPAAGSAARRDVQNVAAAPELAMGALELESRNSTLDPGKPEMMKSPTNTTPHVPAEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 ILDFPAAGSAARRDVQNVAAAPELAMGALELESRNSTLDPGKPEMMKSPTNTTPHVPAEG 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB4 PEASRPPKLHPGLRAAPGQEPPEHMAELQRNEQEQPLGQWHLSKRDTGAALLAESRAEKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 PEASRPPKLHPGLRAAPGQEPPEHMAELQRNEQEQPLGQWHLSKRDTGAALLAESRAEKN 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB4 RLWGPLEVRRVGRSSKQLVDIPEGQLEARAGRGRGQWLQVLGGGFSYLDISLCVGLYSLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 RLWGPLEVRRVGRSSKQLVDIPEGQLEARAGRGRGQWLQVLGGGFSYLDISLCVGLYSLS 670 680 690 700 710 720 730 740 pF1KB4 FMGLLAMYTYFQAKIRALKGHAGHPAA ::::::::::::::::::::::::::: CCDS13 FMGLLAMYTYFQAKIRALKGHAGHPAA 730 740 >>CCDS30950.1 QSOX1 gene_id:5768|Hs108|chr1 (604 aa) initn: 4092 init1: 4092 opt: 4092 Z-score: 3504.5 bits: 658.8 E(32554): 7e-189 Smith-Waterman score: 4092; 99.8% identity (100.0% similar) in 602 aa overlap (1-602:1-602) 10 20 30 40 50 60 pF1KB4 MRRCNSGSGPPPSLLLLLLWLLAVPGANAAPRSALYSPSDPLTLLQADTVRGAVLGSRSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 MRRCNSGSGPPPSLLLLLLWLLAVPGANAAPRSALYSPSDPLTLLQADTVRGAVLGSRSA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 WAVEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLAALDCAEETNSAVCRDFNIPGFPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 WAVEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLAALDCAEETNSAVCRDFNIPGFPT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 VRFFKAFTKNGSGAVFPVAGADVQTLRERLIDALESHHDTWPPACPPLEPAKLEEIDGFF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 VRFFKAFTKNGSGAVFPVAGADVQTLRERLIDALESHHDTWPPACPPLEPAKLEEIDGFF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 ARNNEEYLALIFEKGGSYLAREVALDLSQHKGVAVRRVLNTEANVVRKFGVTDFPSCYLL :::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::: CCDS30 ARNNEEYLALIFEKGGSYLGREVALDLSQHKGVAVRRVLNTEANVVRKFGVTDFPSCYLL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 FRNGSVSRVPVLMESRSFYTAYLQRLSGLTREAAQTTVAPTTANKIAPTVWKLADRSKIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 FRNGSVSRVPVLMESRSFYTAYLQRLSGLTREAAQTTVAPTTANKIAPTVWKLADRSKIY 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 MADLESALHYILRIEVGRFPVLEGQRLVALKKFVAVLAKYFPGRPLVQNFLHSVNEWLKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 MADLESALHYILRIEVGRFPVLEGQRLVALKKFVAVLAKYFPGRPLVQNFLHSVNEWLKR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 QKRNKIPYSFFKTALDDRKEGAVLAKKVNWIGCQGSEPHFRGFPCSLWVLFHFLTVQAAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 QKRNKIPYSFFKTALDDRKEGAVLAKKVNWIGCQGSEPHFRGFPCSLWVLFHFLTVQAAR 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB4 QNVDHSQEAAKAKEVLPAIRGYVHYFFGCRDCASHFEQMAAASMHRVGSPNAAVLWLWSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 QNVDHSQEAAKAKEVLPAIRGYVHYFFGCRDCASHFEQMAAASMHRVGSPNAAVLWLWSS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB4 HNRVNARLAGAPSEDPQFPKVQWPPRELCSACHNERLDVPVWDVEATLNFLKAHFSPSNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 HNRVNARLAGAPSEDPQFPKVQWPPRELCSACHNERLDVPVWDVEATLNFLKAHFSPSNI 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB4 ILDFPAAGSAARRDVQNVAAAPELAMGALELESRNSTLDPGKPEMMKSPTNTTPHVPAEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 ILDFPAAGSAARRDVQNVAAAPELAMGALELESRNSTLDPGKPEMMKSPTNTTPHVPAEG 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB4 PEASRPPKLHPGLRAAPGQEPPEHMAELQRNEQEQPLGQWHLSKRDTGAALLAESRAEKN :: CCDS30 PELI >>CCDS35178.1 QSOX2 gene_id:169714|Hs108|chr9 (698 aa) initn: 1637 init1: 546 opt: 1601 Z-score: 1375.3 bits: 265.0 E(32554): 2.8e-70 Smith-Waterman score: 1610; 38.1% identity (61.6% similar) in 753 aa overlap (8-746:25-697) 10 20 30 pF1KB4 MRRCNSGSGPP-----PSLLLLLLWLLAVPGANAAPRSALYSP : :: : ::.:: . :::..: : :: CCDS35 MAAAGAAVARSPGIGAGPALRARRSPPPRAARLPRLLVLLAAAAVGPGAGGAAR--LYRA 10 20 30 40 50 40 50 60 70 80 90 pF1KB4 S-DPLTLLQADTVRGAVLGSRSAWAVEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLA . : . .:.. .::::. .: .:: :.:..:::::::..::::.::: ::. : :. .: CCDS35 GEDAVWVLDSGSVRGATANSSAAWLVQFYSSWCGHCIGYAPTWRALAGDVRDWASAIRVA 60 70 80 90 100 110 100 110 120 130 140 150 pF1KB4 ALDCAEETNSAVCRDFNIPGFPTVRFFKAFTKN-GSGAVFPVAGADVQTLRERLIDALES :::: :: :.:::.:..: .:: :.::::::. .: : ...:.:. .:: :.. CCDS35 ALDCMEEKNQAVCHDYDIHFYPTFRYFKAFTKEFTTGENFKGPDRELRTVRQTMIDFLQN 120 130 140 150 160 170 160 170 180 190 200 210 pF1KB4 HHD-TWPPACPPLEPAKLEEIDGFFARNNEEYLALIFEKGGSYLAREVALDLSQHKGVAV : . . ::::: :.: . .. ... . .:.:..::...:::.::: ::: .....: CCDS35 HTEGSRPPACPRLDPIQPSDVLSLLDNRGSHYVAIVFESNSSYLGREVILDLIPYESIVV 180 190 200 210 220 230 220 230 240 250 260 270 pF1KB4 RRVLNTEANVVRKFGVTDFPSCYLLFRNGSVSRVPVLMESRSFYTAYLQRLSGLTREAAQ :.:. . ..:.::.. :::::.. ::: . . :. :.:...::. : . ... CCDS35 TRALDGDKAFLEKLGVSSVPSCYLIYPNGSHGLINVVKPLRAFFSSYLKSLPDVRKKSLP 240 250 260 270 280 290 280 290 300 310 320 330 pF1KB4 TTVAPTTANKIAPTVWKLADRSKIYMADLESALHYILRIEVGRFPVLEGQRLVALKKFVA : .. .::. :.::.: .::::.:::.::.:.. : : .: .:: ::. CCDS35 LPEKPHKEENSEIVVWREFDKSKLYTVDLESGLHYLLRVELAAHKSLAGAELKTLKDFVT 300 310 320 330 340 350 340 350 360 370 380 390 pF1KB4 VLAKYFPGRPLVQNFLHSVNEWLKRQKRNKIPYSFFKTALDD--RKEGAVLAKKVNWIGC :::: ::::: :...:. ..::: ..:::. ... : : :.....:.:: CCDS35 VLAKLFPGRPPVKKLLEMLQEWLASLPLDRIPYNAVLDLVNNKMRISGIFLTNHIKWVGC 360 370 380 390 400 410 400 410 420 430 440 450 pF1KB4 QGSEPHFRGFPCSLWVLFHFLTVQAARQ--NVDHSQEAAKAKEVLPAIRGYVHYFFGCRD :::. ..::.::::: ::: :::.:. . . . . :: ..: ::: ::::.. CCDS35 QGSRSELRGYPCSLWKLFHTLTVEASTHPDALVGTGFEDDPQAVLQTMRRYVHTFFGCKE 420 430 440 450 460 470 460 470 480 490 500 510 pF1KB4 CASHFEQMAAASMHRVGSPNAAVLWLWSSHNRVNARLAGAPSEDPQFPKVQWPPRELCSA :. :::.:: :: : .:. :.::::..:: ::.:::: ::::.:::.::: .:: : CCDS35 CGEHFEEMAKESMDSVKTPDQAILWLWKKHNMVNGRLAGHLSEDPRFPKLQWPTPDLCPA 480 490 500 510 520 530 520 530 540 550 560 570 pF1KB4 CHNERLDVPVWDVEATLNFLKAHFSPSNIILDFPAAGSAARRDVQNVAAAPELAMGALEL ::.: . :: .:.::: :.. .:.. . : : . . . :: : : CCDS35 CHEEIKGLASWDEGHVLTFLKQHYGRDNLLDTYSA-------DQGDSSEGGTLARGE-EE 540 550 560 570 580 590 580 590 600 610 620 pF1KB4 ESRNSTLDPGKPEMMKSPTNTTPHVP--AEGPEASRPPKLHPGLRAAPGQEPPEHMAELQ :.: : : ::. .. .: : : ::. . : .:: .: :. :: CCDS35 EKR---LTP--PEVSHGDRDTQSVRPPGALGPRPALPESLHHSL---DGK--------LQ 600 610 620 630 630 640 650 660 670 680 pF1KB4 RNEQEQPLGQWHLSKRDTGAALLAESRAEKNRLWGPLEVRRVGRSSKQLVDIPEGQLEAR : :: ..:: .. : CCDS35 S-------------------------------LDGPGAHKEVGGAA------P------- 640 650 690 700 710 720 730 740 pF1KB4 AGRGRGQWLQVLGGGFSYLDISLCVGLYSLSFMGLLAMYTYFQAKIRALKGHAGHPAA :: :: ::.:::: :: : . :..:: .:... : : . ::: CCDS35 ----------FLGVDFSSLDMSLCVVLYVASSLFLMVMYFFFRVRSRRWKVKHHHPAV 660 670 680 690 747 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 21:27:21 2016 done: Thu Nov 3 21:27:21 2016 Total Scan time: 3.820 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]