FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4140, 747 aa 1>>>pF1KB4140 747 - 747 aa - 747 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.5539+/-0.000371; mu= 15.8729+/- 0.023 mean_var=144.1801+/-28.150, 0's: 0 Z-trim(117.7): 20 B-trim: 0 in 0/58 Lambda= 0.106812 statistics sampled from 29944 (29964) to 29944 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.701), E-opt: 0.2 (0.351), width: 16 Scan time: 12.380 The best scores are: opt bits E(85289) NP_002817 (OMIM: 603120) sulfhydryl oxidase 1 isof ( 747) 5083 795.6 0 NP_001004128 (OMIM: 603120) sulfhydryl oxidase 1 i ( 604) 4092 642.8 1.2e-183 NP_859052 (OMIM: 612860) sulfhydryl oxidase 2 prec ( 698) 1601 259.0 4.9e-68 NP_005304 (OMIM: 602046) protein disulfide-isomera ( 505) 209 44.3 0.0014 XP_011508610 (OMIM: 611099) PREDICTED: protein dis ( 402) 202 43.2 0.0026 NP_001269636 (OMIM: 611099) protein disulfide-isom ( 437) 202 43.2 0.0028 NP_005733 (OMIM: 611099) protein disulfide-isomera ( 440) 202 43.2 0.0028 NP_001269635 (OMIM: 611099) protein disulfide-isom ( 445) 202 43.2 0.0028 NP_001269634 (OMIM: 611099) protein disulfide-isom ( 488) 202 43.2 0.003 NP_001269633 (OMIM: 611099) protein disulfide-isom ( 492) 202 43.3 0.003 NP_000909 (OMIM: 112240,176790) protein disulfide- ( 508) 193 41.9 0.008 >>NP_002817 (OMIM: 603120) sulfhydryl oxidase 1 isoform (747 aa) initn: 5083 init1: 5083 opt: 5083 Z-score: 4242.0 bits: 795.6 E(85289): 0 Smith-Waterman score: 5083; 99.9% identity (100.0% similar) in 747 aa overlap (1-747:1-747) 10 20 30 40 50 60 pF1KB4 MRRCNSGSGPPPSLLLLLLWLLAVPGANAAPRSALYSPSDPLTLLQADTVRGAVLGSRSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MRRCNSGSGPPPSLLLLLLWLLAVPGANAAPRSALYSPSDPLTLLQADTVRGAVLGSRSA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 WAVEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLAALDCAEETNSAVCRDFNIPGFPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 WAVEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLAALDCAEETNSAVCRDFNIPGFPT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 VRFFKAFTKNGSGAVFPVAGADVQTLRERLIDALESHHDTWPPACPPLEPAKLEEIDGFF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 VRFFKAFTKNGSGAVFPVAGADVQTLRERLIDALESHHDTWPPACPPLEPAKLEEIDGFF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 ARNNEEYLALIFEKGGSYLAREVALDLSQHKGVAVRRVLNTEANVVRKFGVTDFPSCYLL :::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::: NP_002 ARNNEEYLALIFEKGGSYLGREVALDLSQHKGVAVRRVLNTEANVVRKFGVTDFPSCYLL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 FRNGSVSRVPVLMESRSFYTAYLQRLSGLTREAAQTTVAPTTANKIAPTVWKLADRSKIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 FRNGSVSRVPVLMESRSFYTAYLQRLSGLTREAAQTTVAPTTANKIAPTVWKLADRSKIY 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 MADLESALHYILRIEVGRFPVLEGQRLVALKKFVAVLAKYFPGRPLVQNFLHSVNEWLKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MADLESALHYILRIEVGRFPVLEGQRLVALKKFVAVLAKYFPGRPLVQNFLHSVNEWLKR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 QKRNKIPYSFFKTALDDRKEGAVLAKKVNWIGCQGSEPHFRGFPCSLWVLFHFLTVQAAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 QKRNKIPYSFFKTALDDRKEGAVLAKKVNWIGCQGSEPHFRGFPCSLWVLFHFLTVQAAR 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB4 QNVDHSQEAAKAKEVLPAIRGYVHYFFGCRDCASHFEQMAAASMHRVGSPNAAVLWLWSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 QNVDHSQEAAKAKEVLPAIRGYVHYFFGCRDCASHFEQMAAASMHRVGSPNAAVLWLWSS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB4 HNRVNARLAGAPSEDPQFPKVQWPPRELCSACHNERLDVPVWDVEATLNFLKAHFSPSNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 HNRVNARLAGAPSEDPQFPKVQWPPRELCSACHNERLDVPVWDVEATLNFLKAHFSPSNI 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB4 ILDFPAAGSAARRDVQNVAAAPELAMGALELESRNSTLDPGKPEMMKSPTNTTPHVPAEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 ILDFPAAGSAARRDVQNVAAAPELAMGALELESRNSTLDPGKPEMMKSPTNTTPHVPAEG 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB4 PEASRPPKLHPGLRAAPGQEPPEHMAELQRNEQEQPLGQWHLSKRDTGAALLAESRAEKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 PEASRPPKLHPGLRAAPGQEPPEHMAELQRNEQEQPLGQWHLSKRDTGAALLAESRAEKN 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB4 RLWGPLEVRRVGRSSKQLVDIPEGQLEARAGRGRGQWLQVLGGGFSYLDISLCVGLYSLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 RLWGPLEVRRVGRSSKQLVDIPEGQLEARAGRGRGQWLQVLGGGFSYLDISLCVGLYSLS 670 680 690 700 710 720 730 740 pF1KB4 FMGLLAMYTYFQAKIRALKGHAGHPAA ::::::::::::::::::::::::::: NP_002 FMGLLAMYTYFQAKIRALKGHAGHPAA 730 740 >>NP_001004128 (OMIM: 603120) sulfhydryl oxidase 1 isofo (604 aa) initn: 4092 init1: 4092 opt: 4092 Z-score: 3417.9 bits: 642.8 E(85289): 1.2e-183 Smith-Waterman score: 4092; 99.8% identity (100.0% similar) in 602 aa overlap (1-602:1-602) 10 20 30 40 50 60 pF1KB4 MRRCNSGSGPPPSLLLLLLWLLAVPGANAAPRSALYSPSDPLTLLQADTVRGAVLGSRSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MRRCNSGSGPPPSLLLLLLWLLAVPGANAAPRSALYSPSDPLTLLQADTVRGAVLGSRSA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 WAVEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLAALDCAEETNSAVCRDFNIPGFPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WAVEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLAALDCAEETNSAVCRDFNIPGFPT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 VRFFKAFTKNGSGAVFPVAGADVQTLRERLIDALESHHDTWPPACPPLEPAKLEEIDGFF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VRFFKAFTKNGSGAVFPVAGADVQTLRERLIDALESHHDTWPPACPPLEPAKLEEIDGFF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 ARNNEEYLALIFEKGGSYLAREVALDLSQHKGVAVRRVLNTEANVVRKFGVTDFPSCYLL :::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::: NP_001 ARNNEEYLALIFEKGGSYLGREVALDLSQHKGVAVRRVLNTEANVVRKFGVTDFPSCYLL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 FRNGSVSRVPVLMESRSFYTAYLQRLSGLTREAAQTTVAPTTANKIAPTVWKLADRSKIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FRNGSVSRVPVLMESRSFYTAYLQRLSGLTREAAQTTVAPTTANKIAPTVWKLADRSKIY 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 MADLESALHYILRIEVGRFPVLEGQRLVALKKFVAVLAKYFPGRPLVQNFLHSVNEWLKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MADLESALHYILRIEVGRFPVLEGQRLVALKKFVAVLAKYFPGRPLVQNFLHSVNEWLKR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 QKRNKIPYSFFKTALDDRKEGAVLAKKVNWIGCQGSEPHFRGFPCSLWVLFHFLTVQAAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QKRNKIPYSFFKTALDDRKEGAVLAKKVNWIGCQGSEPHFRGFPCSLWVLFHFLTVQAAR 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB4 QNVDHSQEAAKAKEVLPAIRGYVHYFFGCRDCASHFEQMAAASMHRVGSPNAAVLWLWSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QNVDHSQEAAKAKEVLPAIRGYVHYFFGCRDCASHFEQMAAASMHRVGSPNAAVLWLWSS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB4 HNRVNARLAGAPSEDPQFPKVQWPPRELCSACHNERLDVPVWDVEATLNFLKAHFSPSNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HNRVNARLAGAPSEDPQFPKVQWPPRELCSACHNERLDVPVWDVEATLNFLKAHFSPSNI 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB4 ILDFPAAGSAARRDVQNVAAAPELAMGALELESRNSTLDPGKPEMMKSPTNTTPHVPAEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ILDFPAAGSAARRDVQNVAAAPELAMGALELESRNSTLDPGKPEMMKSPTNTTPHVPAEG 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB4 PEASRPPKLHPGLRAAPGQEPPEHMAELQRNEQEQPLGQWHLSKRDTGAALLAESRAEKN :: NP_001 PELI >>NP_859052 (OMIM: 612860) sulfhydryl oxidase 2 precurso (698 aa) initn: 1637 init1: 546 opt: 1601 Z-score: 1342.5 bits: 259.0 E(85289): 4.9e-68 Smith-Waterman score: 1610; 38.1% identity (61.6% similar) in 753 aa overlap (8-746:25-697) 10 20 30 pF1KB4 MRRCNSGSGPP-----PSLLLLLLWLLAVPGANAAPRSALYSP : :: : ::.:: . :::..: : :: NP_859 MAAAGAAVARSPGIGAGPALRARRSPPPRAARLPRLLVLLAAAAVGPGAGGAAR--LYRA 10 20 30 40 50 40 50 60 70 80 90 pF1KB4 S-DPLTLLQADTVRGAVLGSRSAWAVEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLA . : . .:.. .::::. .: .:: :.:..:::::::..::::.::: ::. : :. .: NP_859 GEDAVWVLDSGSVRGATANSSAAWLVQFYSSWCGHCIGYAPTWRALAGDVRDWASAIRVA 60 70 80 90 100 110 100 110 120 130 140 150 pF1KB4 ALDCAEETNSAVCRDFNIPGFPTVRFFKAFTKN-GSGAVFPVAGADVQTLRERLIDALES :::: :: :.:::.:..: .:: :.::::::. .: : ...:.:. .:: :.. NP_859 ALDCMEEKNQAVCHDYDIHFYPTFRYFKAFTKEFTTGENFKGPDRELRTVRQTMIDFLQN 120 130 140 150 160 170 160 170 180 190 200 210 pF1KB4 HHD-TWPPACPPLEPAKLEEIDGFFARNNEEYLALIFEKGGSYLAREVALDLSQHKGVAV : . . ::::: :.: . .. ... . .:.:..::...:::.::: ::: .....: NP_859 HTEGSRPPACPRLDPIQPSDVLSLLDNRGSHYVAIVFESNSSYLGREVILDLIPYESIVV 180 190 200 210 220 230 220 230 240 250 260 270 pF1KB4 RRVLNTEANVVRKFGVTDFPSCYLLFRNGSVSRVPVLMESRSFYTAYLQRLSGLTREAAQ :.:. . ..:.::.. :::::.. ::: . . :. :.:...::. : . ... NP_859 TRALDGDKAFLEKLGVSSVPSCYLIYPNGSHGLINVVKPLRAFFSSYLKSLPDVRKKSLP 240 250 260 270 280 290 280 290 300 310 320 330 pF1KB4 TTVAPTTANKIAPTVWKLADRSKIYMADLESALHYILRIEVGRFPVLEGQRLVALKKFVA : .. .::. :.::.: .::::.:::.::.:.. : : .: .:: ::. NP_859 LPEKPHKEENSEIVVWREFDKSKLYTVDLESGLHYLLRVELAAHKSLAGAELKTLKDFVT 300 310 320 330 340 350 340 350 360 370 380 390 pF1KB4 VLAKYFPGRPLVQNFLHSVNEWLKRQKRNKIPYSFFKTALDD--RKEGAVLAKKVNWIGC :::: ::::: :...:. ..::: ..:::. ... : : :.....:.:: NP_859 VLAKLFPGRPPVKKLLEMLQEWLASLPLDRIPYNAVLDLVNNKMRISGIFLTNHIKWVGC 360 370 380 390 400 410 400 410 420 430 440 450 pF1KB4 QGSEPHFRGFPCSLWVLFHFLTVQAARQ--NVDHSQEAAKAKEVLPAIRGYVHYFFGCRD :::. ..::.::::: ::: :::.:. . . . . :: ..: ::: ::::.. NP_859 QGSRSELRGYPCSLWKLFHTLTVEASTHPDALVGTGFEDDPQAVLQTMRRYVHTFFGCKE 420 430 440 450 460 470 460 470 480 490 500 510 pF1KB4 CASHFEQMAAASMHRVGSPNAAVLWLWSSHNRVNARLAGAPSEDPQFPKVQWPPRELCSA :. :::.:: :: : .:. :.::::..:: ::.:::: ::::.:::.::: .:: : NP_859 CGEHFEEMAKESMDSVKTPDQAILWLWKKHNMVNGRLAGHLSEDPRFPKLQWPTPDLCPA 480 490 500 510 520 530 520 530 540 550 560 570 pF1KB4 CHNERLDVPVWDVEATLNFLKAHFSPSNIILDFPAAGSAARRDVQNVAAAPELAMGALEL ::.: . :: .:.::: :.. .:.. . : : . . . :: : : NP_859 CHEEIKGLASWDEGHVLTFLKQHYGRDNLLDTYSA-------DQGDSSEGGTLARGE-EE 540 550 560 570 580 590 580 590 600 610 620 pF1KB4 ESRNSTLDPGKPEMMKSPTNTTPHVP--AEGPEASRPPKLHPGLRAAPGQEPPEHMAELQ :.: : : ::. .. .: : : ::. . : .:: .: :. :: NP_859 EKR---LTP--PEVSHGDRDTQSVRPPGALGPRPALPESLHHSL---DGK--------LQ 600 610 620 630 630 640 650 660 670 680 pF1KB4 RNEQEQPLGQWHLSKRDTGAALLAESRAEKNRLWGPLEVRRVGRSSKQLVDIPEGQLEAR : :: ..:: .. : NP_859 S-------------------------------LDGPGAHKEVGGAA------P------- 640 650 690 700 710 720 730 740 pF1KB4 AGRGRGQWLQVLGGGFSYLDISLCVGLYSLSFMGLLAMYTYFQAKIRALKGHAGHPAA :: :: ::.:::: :: : . :..:: .:... : : . ::: NP_859 ----------FLGVDFSSLDMSLCVVLYVASSLFLMVMYFFFRVRSRRWKVKHHHPAV 660 670 680 690 >>NP_005304 (OMIM: 602046) protein disulfide-isomerase A (505 aa) initn: 240 init1: 121 opt: 209 Z-score: 185.0 bits: 44.3 E(85289): 0.0014 Smith-Waterman score: 209; 36.6% identity (58.9% similar) in 112 aa overlap (25-132:10-114) 10 20 30 40 50 pF1KB4 MRRCNSGSGPPPSLLLLLLWLLAVPGAN---AAPRSALYSPSDPLTLLQAD-TVRGAVLG ::. :: : : . :: : : . . : . : NP_005 MRLRRLALFPGVALLLAAAR--LAAASDVLELTDDNFESRISDTG 10 20 30 40 60 70 80 90 100 110 pF1KB4 SRSAWAVEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLAALDCAEETNSAVCRDFNIP : . ::::: ::::: .:: ..: : .:. : :: .::. .::. : ... NP_005 SAGLMLVEFFAPWCGHCKRLAPEYEAAATRLKGIVP---LAKVDCTANTNT--CNKYGVS 50 60 70 80 90 120 130 140 150 160 170 pF1KB4 GFPTVRFFKAFTKNGSGAVFPVAGADVQTLRERLIDALESHHDTWPPACPPLEPAKLEEI :.::...:. . :. NP_005 GYPTLKIFRDGEEAGAYDGPRTADGIVSHLKKQAGPASVPLRTEEEFKKFISDKDASIVG 100 110 120 130 140 150 >>XP_011508610 (OMIM: 611099) PREDICTED: protein disulfi (402 aa) initn: 166 init1: 166 opt: 202 Z-score: 180.4 bits: 43.2 E(85289): 0.0026 Smith-Waterman score: 223; 34.8% identity (55.1% similar) in 158 aa overlap (32-187:153-294) 10 20 30 40 50 60 pF1KB4 RRCNSGSGPPPSLLLLLLWLLAVPGANAAPRSALYSPSDPLTLLQADTVRGAVLGSRSAW :: : .: . : . :. :: :...: XP_011 IVDAALSALRQLVKDRLGGRSGGYSSGKQGRSDSSSKKDVIELTD-DSFDKNVLDSEDVW 130 140 150 160 170 180 70 80 90 100 110 120 pF1KB4 AVEFFASWCGHCIAFAPTWKALAEDVKAW-RPALYLAALDCAEETNSAVCRDFNIPGFPT :::.: ::::: . : : : : .:: . . :::.: . .:... ..: :::: XP_011 MVEFYAPWCGHCKNLEPEWAAAASEVKEQTKGKVKLAAVDAT--VNQVLASRYGIRGFPT 190 200 210 220 230 130 140 150 160 170 180 pF1KB4 VRFFKAFTKNGSGAVFPVAGADVQTLRERLIDALESHHDTWPPACPPLEPAKLEEIDGFF ...:. :. : :: : . : : : . : . :: : :: :. . XP_011 IKIFQ---KGES----PV---DYDGGRTRS-DIVSRALDLFSDNAPP--PELLEIINEDI 240 250 260 270 280 190 200 210 220 230 pF1KB4 A-RNNEEYLALIFEKGGSYLAREVALDLSQHKGVAVRRVLNTEANVVRKFGVTDFPSCYL : :. ::. XP_011 AKRTCEEHQLCVVAVLPHILDTGAAGRNSYLEVLLKLADKYKKKMWGWLWTEAGAQSELE 290 300 310 320 330 340 >>NP_001269636 (OMIM: 611099) protein disulfide-isomeras (437 aa) initn: 194 init1: 166 opt: 202 Z-score: 180.0 bits: 43.2 E(85289): 0.0028 Smith-Waterman score: 223; 34.8% identity (55.1% similar) in 158 aa overlap (32-187:150-291) 10 20 30 40 50 60 pF1KB4 RRCNSGSGPPPSLLLLLLWLLAVPGANAAPRSALYSPSDPLTLLQADTVRGAVLGSRSAW :: : .: . : . :. :: :...: NP_001 IVDAALSALRQLVKDRLGGRSGGYSSGKQGRSDSSSKKDVIELTD-DSFDKNVLDSEDVW 120 130 140 150 160 170 70 80 90 100 110 120 pF1KB4 AVEFFASWCGHCIAFAPTWKALAEDVKAW-RPALYLAALDCAEETNSAVCRDFNIPGFPT :::.: ::::: . : : : : .:: . . :::.: . .:... ..: :::: NP_001 MVEFYAPWCGHCKNLEPEWAAAASEVKEQTKGKVKLAAVDAT--VNQVLASRYGIRGFPT 180 190 200 210 220 230 130 140 150 160 170 180 pF1KB4 VRFFKAFTKNGSGAVFPVAGADVQTLRERLIDALESHHDTWPPACPPLEPAKLEEIDGFF ...:. :. : :: : . : : : . : . :: : :: :. . NP_001 IKIFQ---KGES----PV---DYDGGRTRS-DIVSRALDLFSDNAPP--PELLEIINEDI 240 250 260 270 280 190 200 210 220 230 pF1KB4 A-RNNEEYLALIFEKGGSYLAREVALDLSQHKGVAVRRVLNTEANVVRKFGVTDFPSCYL : :. ::. NP_001 AKRTCEEHQLCVVAVLPHILDTGAAGRNSYLEVLLKLADKYKKKMWGWLWTEAGAQSELE 290 300 310 320 330 340 >>NP_005733 (OMIM: 611099) protein disulfide-isomerase A (440 aa) initn: 194 init1: 166 opt: 202 Z-score: 179.9 bits: 43.2 E(85289): 0.0028 Smith-Waterman score: 223; 34.8% identity (55.1% similar) in 158 aa overlap (32-187:153-294) 10 20 30 40 50 60 pF1KB4 RRCNSGSGPPPSLLLLLLWLLAVPGANAAPRSALYSPSDPLTLLQADTVRGAVLGSRSAW :: : .: . : . :. :: :...: NP_005 IVDAALSALRQLVKDRLGGRSGGYSSGKQGRSDSSSKKDVIELTD-DSFDKNVLDSEDVW 130 140 150 160 170 180 70 80 90 100 110 120 pF1KB4 AVEFFASWCGHCIAFAPTWKALAEDVKAW-RPALYLAALDCAEETNSAVCRDFNIPGFPT :::.: ::::: . : : : : .:: . . :::.: . .:... ..: :::: NP_005 MVEFYAPWCGHCKNLEPEWAAAASEVKEQTKGKVKLAAVDAT--VNQVLASRYGIRGFPT 190 200 210 220 230 130 140 150 160 170 180 pF1KB4 VRFFKAFTKNGSGAVFPVAGADVQTLRERLIDALESHHDTWPPACPPLEPAKLEEIDGFF ...:. :. : :: : . : : : . : . :: : :: :. . NP_005 IKIFQ---KGES----PV---DYDGGRTRS-DIVSRALDLFSDNAPP--PELLEIINEDI 240 250 260 270 280 190 200 210 220 230 pF1KB4 A-RNNEEYLALIFEKGGSYLAREVALDLSQHKGVAVRRVLNTEANVVRKFGVTDFPSCYL : :. ::. NP_005 AKRTCEEHQLCVVAVLPHILDTGAAGRNSYLEVLLKLADKYKKKMWGWLWTEAGAQSELE 290 300 310 320 330 340 >>NP_001269635 (OMIM: 611099) protein disulfide-isomeras (445 aa) initn: 194 init1: 166 opt: 202 Z-score: 179.9 bits: 43.2 E(85289): 0.0028 Smith-Waterman score: 223; 34.8% identity (55.1% similar) in 158 aa overlap (32-187:158-299) 10 20 30 40 50 60 pF1KB4 RRCNSGSGPPPSLLLLLLWLLAVPGANAAPRSALYSPSDPLTLLQADTVRGAVLGSRSAW :: : .: . : . :. :: :...: NP_001 IVDAALSALRQLVKDRLGGRSGGYSSGKQGRSDSSSKKDVIELTD-DSFDKNVLDSEDVW 130 140 150 160 170 180 70 80 90 100 110 120 pF1KB4 AVEFFASWCGHCIAFAPTWKALAEDVKAW-RPALYLAALDCAEETNSAVCRDFNIPGFPT :::.: ::::: . : : : : .:: . . :::.: . .:... ..: :::: NP_001 MVEFYAPWCGHCKNLEPEWAAAASEVKEQTKGKVKLAAVDAT--VNQVLASRYGIRGFPT 190 200 210 220 230 240 130 140 150 160 170 180 pF1KB4 VRFFKAFTKNGSGAVFPVAGADVQTLRERLIDALESHHDTWPPACPPLEPAKLEEIDGFF ...:. :. : :: : . : : : . : . :: : :: :. . NP_001 IKIFQ---KGES----PV---DYDGGRTRS-DIVSRALDLFSDNAPP--PELLEIINEDI 250 260 270 280 290 190 200 210 220 230 pF1KB4 A-RNNEEYLALIFEKGGSYLAREVALDLSQHKGVAVRRVLNTEANVVRKFGVTDFPSCYL : :. ::. NP_001 AKRTCEEHQLCVVAVLPHILDTGAAGRNSYLEVLLKLADKYKKKMWGWLWTEAGAQSELE 300 310 320 330 340 350 >>NP_001269634 (OMIM: 611099) protein disulfide-isomeras (488 aa) initn: 194 init1: 166 opt: 202 Z-score: 179.4 bits: 43.2 E(85289): 0.003 Smith-Waterman score: 223; 34.8% identity (55.1% similar) in 158 aa overlap (32-187:201-342) 10 20 30 40 50 60 pF1KB4 RRCNSGSGPPPSLLLLLLWLLAVPGANAAPRSALYSPSDPLTLLQADTVRGAVLGSRSAW :: : .: . : . :. :: :...: NP_001 IVDAALSALRQLVKDRLGGRSGGYSSGKQGRSDSSSKKDVIELTD-DSFDKNVLDSEDVW 180 190 200 210 220 70 80 90 100 110 120 pF1KB4 AVEFFASWCGHCIAFAPTWKALAEDVKAW-RPALYLAALDCAEETNSAVCRDFNIPGFPT :::.: ::::: . : : : : .:: . . :::.: . .:... ..: :::: NP_001 MVEFYAPWCGHCKNLEPEWAAAASEVKEQTKGKVKLAAVDAT--VNQVLASRYGIRGFPT 230 240 250 260 270 280 130 140 150 160 170 180 pF1KB4 VRFFKAFTKNGSGAVFPVAGADVQTLRERLIDALESHHDTWPPACPPLEPAKLEEIDGFF ...:. :. : :: : . : : : . : . :: : :: :. . NP_001 IKIFQ---KGES----PV---DYDGGRTRS-DIVSRALDLFSDNAPP--PELLEIINEDI 290 300 310 320 330 190 200 210 220 230 pF1KB4 A-RNNEEYLALIFEKGGSYLAREVALDLSQHKGVAVRRVLNTEANVVRKFGVTDFPSCYL : :. ::. NP_001 AKRTCEEHQLCVVAVLPHILDTGAAGRNSYLEVLLKLADKYKKKMWGWLWTEAGAQSELE 340 350 360 370 380 390 >>NP_001269633 (OMIM: 611099) protein disulfide-isomeras (492 aa) initn: 194 init1: 166 opt: 202 Z-score: 179.3 bits: 43.3 E(85289): 0.003 Smith-Waterman score: 223; 34.8% identity (55.1% similar) in 158 aa overlap (32-187:205-346) 10 20 30 40 50 60 pF1KB4 RRCNSGSGPPPSLLLLLLWLLAVPGANAAPRSALYSPSDPLTLLQADTVRGAVLGSRSAW :: : .: . : . :. :: :...: NP_001 IVDAALSALRQLVKDRLGGRSGGYSSGKQGRSDSSSKKDVIELTD-DSFDKNVLDSEDVW 180 190 200 210 220 230 70 80 90 100 110 120 pF1KB4 AVEFFASWCGHCIAFAPTWKALAEDVKAW-RPALYLAALDCAEETNSAVCRDFNIPGFPT :::.: ::::: . : : : : .:: . . :::.: . .:... ..: :::: NP_001 MVEFYAPWCGHCKNLEPEWAAAASEVKEQTKGKVKLAAVDAT--VNQVLASRYGIRGFPT 240 250 260 270 280 290 130 140 150 160 170 180 pF1KB4 VRFFKAFTKNGSGAVFPVAGADVQTLRERLIDALESHHDTWPPACPPLEPAKLEEIDGFF ...:. :. : :: : . : : : . : . :: : :: :. . NP_001 IKIFQ---KGES----PV---DYDGGRTRS-DIVSRALDLFSDNAPP--PELLEIINEDI 300 310 320 330 190 200 210 220 230 pF1KB4 A-RNNEEYLALIFEKGGSYLAREVALDLSQHKGVAVRRVLNTEANVVRKFGVTDFPSCYL : :. ::. NP_001 AKRTCEEHQLCVVAVLPHILDTGAAGRNSYLEVLLKLADKYKKKMWGWLWTEAGAQSELE 340 350 360 370 380 390 747 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 21:27:22 2016 done: Thu Nov 3 21:27:23 2016 Total Scan time: 12.380 Total Display time: 0.100 Function used was FASTA [36.3.4 Apr, 2011]