FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4144, 156 aa 1>>>pF1KB4144 156 - 156 aa - 156 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.6305+/-0.000392; mu= 8.3464+/- 0.025 mean_var=158.9921+/-31.303, 0's: 0 Z-trim(118.1): 35 B-trim: 400 in 1/56 Lambda= 0.101715 statistics sampled from 30585 (30620) to 30585 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.72), E-opt: 0.2 (0.359), width: 16 Scan time: 5.890 The best scores are: opt bits E(85289) NP_002351 (OMIM: 600197) transcription factor MafK ( 156) 950 150.2 1.3e-36 XP_006715836 (OMIM: 600197) PREDICTED: transcripti ( 156) 950 150.2 1.3e-36 XP_005249908 (OMIM: 600197) PREDICTED: transcripti ( 156) 950 150.2 1.3e-36 XP_011521880 (OMIM: 602020) PREDICTED: transcripti ( 162) 675 109.8 1.9e-24 NP_116100 (OMIM: 602020) transcription factor MafG ( 162) 675 109.8 1.9e-24 NP_002350 (OMIM: 602020) transcription factor MafG ( 162) 675 109.8 1.9e-24 NP_036455 (OMIM: 604877) transcription factor MafF ( 164) 618 101.5 6.3e-22 NP_001155044 (OMIM: 604877) transcription factor M ( 164) 618 101.5 6.3e-22 NP_001155045 (OMIM: 604877) transcription factor M ( 164) 618 101.5 6.3e-22 NP_001155046 (OMIM: 604877) transcription factor M ( 135) 518 86.7 1.4e-17 NP_005452 (OMIM: 166300,608968,617041) transcripti ( 323) 380 66.8 3.2e-11 NP_963883 (OMIM: 610303) transcription factor MafA ( 353) 346 61.9 1.1e-09 NP_001026974 (OMIM: 177075,601088,610202) transcri ( 373) 343 61.5 1.5e-09 XP_016878722 (OMIM: 177075,601088,610202) PREDICTE ( 383) 343 61.5 1.6e-09 XP_016878724 (OMIM: 177075,601088,610202) PREDICTE ( 383) 343 61.5 1.6e-09 XP_016878723 (OMIM: 177075,601088,610202) PREDICTE ( 383) 343 61.5 1.6e-09 NP_005351 (OMIM: 177075,601088,610202) transcripti ( 403) 343 61.5 1.6e-09 XP_016876839 (OMIM: 162080,613750) PREDICTED: neur ( 132) 278 51.5 5.7e-07 XP_011535108 (OMIM: 162080,613750) PREDICTED: neur ( 234) 278 51.7 8.3e-07 XP_011535106 (OMIM: 162080,613750) PREDICTED: neur ( 237) 276 51.4 1e-06 XP_011535107 (OMIM: 162080,613750) PREDICTED: neur ( 237) 276 51.4 1e-06 XP_011535104 (OMIM: 162080,613750) PREDICTED: neur ( 237) 276 51.4 1e-06 NP_006168 (OMIM: 162080,613750) neural retina-spec ( 237) 276 51.4 1e-06 XP_005267767 (OMIM: 162080,613750) PREDICTED: neur ( 237) 276 51.4 1e-06 XP_005267766 (OMIM: 162080,613750) PREDICTED: neur ( 237) 276 51.4 1e-06 XP_005267765 (OMIM: 162080,613750) PREDICTED: neur ( 237) 276 51.4 1e-06 XP_011535103 (OMIM: 162080,613750) PREDICTED: neur ( 339) 276 51.6 1.3e-06 >>NP_002351 (OMIM: 600197) transcription factor MafK [Ho (156 aa) initn: 950 init1: 950 opt: 950 Z-score: 778.2 bits: 150.2 E(85289): 1.3e-36 Smith-Waterman score: 950; 100.0% identity (100.0% similar) in 156 aa overlap (1-156:1-156) 10 20 30 40 50 60 pF1KB4 MTTNPKPNKALKVKKEAGENAPVLSDDELVSMSVRELNQHLRGLTKEEVTRLKQRRRTLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MTTNPKPNKALKVKKEAGENAPVLSDDELVSMSVRELNQHLRGLTKEEVTRLKQRRRTLK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 NRGYAASCRIKRVTQKEELERQRVELQQEVEKLARENSSMRLELDALRSKYEALQTFART :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 NRGYAASCRIKRVTQKEELERQRVELQQEVEKLARENSSMRLELDALRSKYEALQTFART 70 80 90 100 110 120 130 140 150 pF1KB4 VARGPVAPSKVATTSVITIVKSTELSSTSVPFSAAS :::::::::::::::::::::::::::::::::::: NP_002 VARGPVAPSKVATTSVITIVKSTELSSTSVPFSAAS 130 140 150 >>XP_006715836 (OMIM: 600197) PREDICTED: transcription f (156 aa) initn: 950 init1: 950 opt: 950 Z-score: 778.2 bits: 150.2 E(85289): 1.3e-36 Smith-Waterman score: 950; 100.0% identity (100.0% similar) in 156 aa overlap (1-156:1-156) 10 20 30 40 50 60 pF1KB4 MTTNPKPNKALKVKKEAGENAPVLSDDELVSMSVRELNQHLRGLTKEEVTRLKQRRRTLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MTTNPKPNKALKVKKEAGENAPVLSDDELVSMSVRELNQHLRGLTKEEVTRLKQRRRTLK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 NRGYAASCRIKRVTQKEELERQRVELQQEVEKLARENSSMRLELDALRSKYEALQTFART :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NRGYAASCRIKRVTQKEELERQRVELQQEVEKLARENSSMRLELDALRSKYEALQTFART 70 80 90 100 110 120 130 140 150 pF1KB4 VARGPVAPSKVATTSVITIVKSTELSSTSVPFSAAS :::::::::::::::::::::::::::::::::::: XP_006 VARGPVAPSKVATTSVITIVKSTELSSTSVPFSAAS 130 140 150 >>XP_005249908 (OMIM: 600197) PREDICTED: transcription f (156 aa) initn: 950 init1: 950 opt: 950 Z-score: 778.2 bits: 150.2 E(85289): 1.3e-36 Smith-Waterman score: 950; 100.0% identity (100.0% similar) in 156 aa overlap (1-156:1-156) 10 20 30 40 50 60 pF1KB4 MTTNPKPNKALKVKKEAGENAPVLSDDELVSMSVRELNQHLRGLTKEEVTRLKQRRRTLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MTTNPKPNKALKVKKEAGENAPVLSDDELVSMSVRELNQHLRGLTKEEVTRLKQRRRTLK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 NRGYAASCRIKRVTQKEELERQRVELQQEVEKLARENSSMRLELDALRSKYEALQTFART :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NRGYAASCRIKRVTQKEELERQRVELQQEVEKLARENSSMRLELDALRSKYEALQTFART 70 80 90 100 110 120 130 140 150 pF1KB4 VARGPVAPSKVATTSVITIVKSTELSSTSVPFSAAS :::::::::::::::::::::::::::::::::::: XP_005 VARGPVAPSKVATTSVITIVKSTELSSTSVPFSAAS 130 140 150 >>XP_011521880 (OMIM: 602020) PREDICTED: transcription f (162 aa) initn: 675 init1: 675 opt: 675 Z-score: 559.9 bits: 109.8 E(85289): 1.9e-24 Smith-Waterman score: 694; 75.0% identity (86.5% similar) in 156 aa overlap (1-142:1-156) 10 20 30 40 50 60 pF1KB4 MTTNPKPNKALKVKKEAGENAPVLSDDELVSMSVRELNQHLRGLTKEEVTRLKQRRRTLK ::: : :::::::.: :::. :.:.:::.:::::::::::::.:::...::::::::: XP_011 MTTPNKGNKALKVKREPGENGTSLTDEELVTMSVRELNQHLRGLSKEEIVQLKQRRRTLK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 NRGYAASCRIKRVTQKEELERQRVELQQEVEKLARENSSMRLELDALRSKYEALQTFART :::::::::.::::::::::.:..:::::::::: ::.::.::::::::::::::::::: XP_011 NRGYAASCRVKRVTQKEELEKQKAELQQEVEKLASENASMKLELDALRSKYEALQTFART 70 80 90 100 110 120 130 140 150 pF1KB4 VARGPVAPS--------------KVATTSVITIVKSTELSSTSVPFSAAS :::.::::. :::.::::::::: XP_011 VARSPVAPARGPLAAGLGPLVPGKVAATSVITIVKSKTDARS 130 140 150 160 >>NP_116100 (OMIM: 602020) transcription factor MafG [Ho (162 aa) initn: 675 init1: 675 opt: 675 Z-score: 559.9 bits: 109.8 E(85289): 1.9e-24 Smith-Waterman score: 694; 75.0% identity (86.5% similar) in 156 aa overlap (1-142:1-156) 10 20 30 40 50 60 pF1KB4 MTTNPKPNKALKVKKEAGENAPVLSDDELVSMSVRELNQHLRGLTKEEVTRLKQRRRTLK ::: : :::::::.: :::. :.:.:::.:::::::::::::.:::...::::::::: NP_116 MTTPNKGNKALKVKREPGENGTSLTDEELVTMSVRELNQHLRGLSKEEIVQLKQRRRTLK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 NRGYAASCRIKRVTQKEELERQRVELQQEVEKLARENSSMRLELDALRSKYEALQTFART :::::::::.::::::::::.:..:::::::::: ::.::.::::::::::::::::::: NP_116 NRGYAASCRVKRVTQKEELEKQKAELQQEVEKLASENASMKLELDALRSKYEALQTFART 70 80 90 100 110 120 130 140 150 pF1KB4 VARGPVAPS--------------KVATTSVITIVKSTELSSTSVPFSAAS :::.::::. :::.::::::::: NP_116 VARSPVAPARGPLAAGLGPLVPGKVAATSVITIVKSKTDARS 130 140 150 160 >>NP_002350 (OMIM: 602020) transcription factor MafG [Ho (162 aa) initn: 675 init1: 675 opt: 675 Z-score: 559.9 bits: 109.8 E(85289): 1.9e-24 Smith-Waterman score: 694; 75.0% identity (86.5% similar) in 156 aa overlap (1-142:1-156) 10 20 30 40 50 60 pF1KB4 MTTNPKPNKALKVKKEAGENAPVLSDDELVSMSVRELNQHLRGLTKEEVTRLKQRRRTLK ::: : :::::::.: :::. :.:.:::.:::::::::::::.:::...::::::::: NP_002 MTTPNKGNKALKVKREPGENGTSLTDEELVTMSVRELNQHLRGLSKEEIVQLKQRRRTLK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 NRGYAASCRIKRVTQKEELERQRVELQQEVEKLARENSSMRLELDALRSKYEALQTFART :::::::::.::::::::::.:..:::::::::: ::.::.::::::::::::::::::: NP_002 NRGYAASCRVKRVTQKEELEKQKAELQQEVEKLASENASMKLELDALRSKYEALQTFART 70 80 90 100 110 120 130 140 150 pF1KB4 VARGPVAPS--------------KVATTSVITIVKSTELSSTSVPFSAAS :::.::::. :::.::::::::: NP_002 VARSPVAPARGPLAAGLGPLVPGKVAATSVITIVKSKTDARS 130 140 150 160 >>NP_036455 (OMIM: 604877) transcription factor MafF iso (164 aa) initn: 608 init1: 608 opt: 618 Z-score: 514.7 bits: 101.5 E(85289): 6.3e-22 Smith-Waterman score: 618; 68.0% identity (88.0% similar) in 150 aa overlap (1-148:1-148) 10 20 30 40 50 60 pF1KB4 MTTNPKPNKALKVKKEAGENAPVLSDDELVSMSVRELNQHLRGLTKEEVTRLKQRRRTLK :...: .::::.:.: .::.: :::. :...::::::.:::::. :::::::::::::: NP_036 MSVDPLSSKALKIKRELSENTPHLSDEALMGLSVRELNRHLRGLSAEEVTRLKQRRRTLK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 NRGYAASCRIKRVTQKEELERQRVELQQEVEKLARENSSMRLELDALRSKYEALQTFART :::::::::.::: :::::..:. ::..::.::::::..:::::::::.: :::: :::. NP_036 NRGYAASCRVKRVCQKEELQKQKSELEREVDKLARENAAMRLELDALRGKCEALQGFARS 70 80 90 100 110 120 130 140 150 pF1KB4 VA--RGPVAPSKVATTSVITIVKSTELSSTSVPFSAAS :: :::. . :: .::::::::: :.. NP_036 VAAARGPA--TLVAPASVITIVKSTPGSGSGPAHGPDPAHGPASCS 130 140 150 160 >>NP_001155044 (OMIM: 604877) transcription factor MafF (164 aa) initn: 608 init1: 608 opt: 618 Z-score: 514.7 bits: 101.5 E(85289): 6.3e-22 Smith-Waterman score: 618; 68.0% identity (88.0% similar) in 150 aa overlap (1-148:1-148) 10 20 30 40 50 60 pF1KB4 MTTNPKPNKALKVKKEAGENAPVLSDDELVSMSVRELNQHLRGLTKEEVTRLKQRRRTLK :...: .::::.:.: .::.: :::. :...::::::.:::::. :::::::::::::: NP_001 MSVDPLSSKALKIKRELSENTPHLSDEALMGLSVRELNRHLRGLSAEEVTRLKQRRRTLK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 NRGYAASCRIKRVTQKEELERQRVELQQEVEKLARENSSMRLELDALRSKYEALQTFART :::::::::.::: :::::..:. ::..::.::::::..:::::::::.: :::: :::. NP_001 NRGYAASCRVKRVCQKEELQKQKSELEREVDKLARENAAMRLELDALRGKCEALQGFARS 70 80 90 100 110 120 130 140 150 pF1KB4 VA--RGPVAPSKVATTSVITIVKSTELSSTSVPFSAAS :: :::. . :: .::::::::: :.. NP_001 VAAARGPA--TLVAPASVITIVKSTPGSGSGPAHGPDPAHGPASCS 130 140 150 160 >>NP_001155045 (OMIM: 604877) transcription factor MafF (164 aa) initn: 608 init1: 608 opt: 618 Z-score: 514.7 bits: 101.5 E(85289): 6.3e-22 Smith-Waterman score: 618; 68.0% identity (88.0% similar) in 150 aa overlap (1-148:1-148) 10 20 30 40 50 60 pF1KB4 MTTNPKPNKALKVKKEAGENAPVLSDDELVSMSVRELNQHLRGLTKEEVTRLKQRRRTLK :...: .::::.:.: .::.: :::. :...::::::.:::::. :::::::::::::: NP_001 MSVDPLSSKALKIKRELSENTPHLSDEALMGLSVRELNRHLRGLSAEEVTRLKQRRRTLK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 NRGYAASCRIKRVTQKEELERQRVELQQEVEKLARENSSMRLELDALRSKYEALQTFART :::::::::.::: :::::..:. ::..::.::::::..:::::::::.: :::: :::. NP_001 NRGYAASCRVKRVCQKEELQKQKSELEREVDKLARENAAMRLELDALRGKCEALQGFARS 70 80 90 100 110 120 130 140 150 pF1KB4 VA--RGPVAPSKVATTSVITIVKSTELSSTSVPFSAAS :: :::. . :: .::::::::: :.. NP_001 VAAARGPA--TLVAPASVITIVKSTPGSGSGPAHGPDPAHGPASCS 130 140 150 160 >>NP_001155046 (OMIM: 604877) transcription factor MafF (135 aa) initn: 508 init1: 508 opt: 518 Z-score: 436.4 bits: 86.7 E(85289): 1.4e-17 Smith-Waterman score: 518; 71.9% identity (89.3% similar) in 121 aa overlap (30-148:1-119) 10 20 30 40 50 60 pF1KB4 MTTNPKPNKALKVKKEAGENAPVLSDDELVSMSVRELNQHLRGLTKEEVTRLKQRRRTLK ...::::::.:::::. :::::::::::::: NP_001 MGLSVRELNRHLRGLSAEEVTRLKQRRRTLK 10 20 30 70 80 90 100 110 120 pF1KB4 NRGYAASCRIKRVTQKEELERQRVELQQEVEKLARENSSMRLELDALRSKYEALQTFART :::::::::.::: :::::..:. ::..::.::::::..:::::::::.: :::: :::. NP_001 NRGYAASCRVKRVCQKEELQKQKSELEREVDKLARENAAMRLELDALRGKCEALQGFARS 40 50 60 70 80 90 130 140 150 pF1KB4 VA--RGPVAPSKVATTSVITIVKSTELSSTSVPFSAAS :: :::. . :: .::::::::: :.. NP_001 VAAARGPA--TLVAPASVITIVKSTPGSGSGPAHGPDPAHGPASCS 100 110 120 130 156 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 21:28:41 2016 done: Thu Nov 3 21:28:42 2016 Total Scan time: 5.890 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]