FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4146, 619 aa 1>>>pF1KB4146 619 - 619 aa - 619 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.4790+/-0.000438; mu= 18.5009+/- 0.027 mean_var=71.2600+/-14.505, 0's: 0 Z-trim(110.5): 112 B-trim: 816 in 1/49 Lambda= 0.151933 statistics sampled from 18798 (18914) to 18798 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.579), E-opt: 0.2 (0.222), width: 16 Scan time: 10.200 The best scores are: opt bits E(85289) NP_000848 (OMIM: 139397) guanylate cyclase soluble ( 619) 4107 910.0 0 NP_001278881 (OMIM: 139397) guanylate cyclase solu ( 599) 3927 870.5 0 XP_016863622 (OMIM: 139397) PREDICTED: guanylate c ( 551) 3671 814.4 0 NP_001278884 (OMIM: 139397) guanylate cyclase solu ( 551) 3671 814.4 0 XP_016863621 (OMIM: 139397) PREDICTED: guanylate c ( 551) 3671 814.4 0 NP_001278880 (OMIM: 139397) guanylate cyclase solu ( 641) 3465 769.3 0 NP_001278883 (OMIM: 139397) guanylate cyclase solu ( 586) 2582 575.7 1.5e-163 XP_011530203 (OMIM: 139397) PREDICTED: guanylate c ( 662) 2582 575.7 1.7e-163 XP_016863619 (OMIM: 139397) PREDICTED: guanylate c ( 594) 2146 480.2 9e-135 NP_001278882 (OMIM: 139397) guanylate cyclase solu ( 594) 2146 480.2 9e-135 XP_016863620 (OMIM: 139397) PREDICTED: guanylate c ( 594) 2146 480.2 9e-135 NP_000846 (OMIM: 601244) guanylate cyclase soluble ( 732) 952 218.5 6.5e-56 XP_011530202 (OMIM: 139396,615750) PREDICTED: guan ( 455) 773 179.1 2.8e-44 NP_001124157 (OMIM: 139396,615750) guanylate cycla ( 455) 773 179.1 2.8e-44 XP_006714261 (OMIM: 139396,615750) PREDICTED: guan ( 455) 773 179.1 2.8e-44 XP_005263013 (OMIM: 139396,615750) PREDICTED: guan ( 455) 773 179.1 2.8e-44 XP_005263014 (OMIM: 139396,615750) PREDICTED: guan ( 455) 773 179.1 2.8e-44 NP_000847 (OMIM: 139396,615750) guanylate cyclase ( 690) 773 179.2 4e-44 NP_001124154 (OMIM: 139396,615750) guanylate cycla ( 690) 773 179.2 4e-44 NP_001124156 (OMIM: 139396,615750) guanylate cycla ( 690) 773 179.2 4e-44 XP_006714259 (OMIM: 139396,615750) PREDICTED: guan ( 690) 773 179.2 4e-44 XP_006714260 (OMIM: 139396,615750) PREDICTED: guan ( 690) 773 179.2 4e-44 NP_001243378 (OMIM: 139396,615750) guanylate cycla ( 690) 773 179.2 4e-44 XP_005263012 (OMIM: 139396,615750) PREDICTED: guan ( 690) 773 179.2 4e-44 NP_001124155 (OMIM: 139396,615750) guanylate cycla ( 690) 773 179.2 4e-44 NP_001124159 (OMIM: 139396,615750) guanylate cycla ( 624) 770 178.6 5.8e-44 NP_001243353 (OMIM: 601244) guanylate cyclase solu ( 763) 746 173.3 2.6e-42 XP_005245275 (OMIM: 108960) PREDICTED: atrial natr (1035) 573 135.5 8.9e-31 NP_000897 (OMIM: 108960) atrial natriuretic peptid (1061) 573 135.5 9.1e-31 XP_016870237 (OMIM: 108961,602875,615923,616255) P ( 579) 569 134.5 1e-30 XP_016870239 (OMIM: 108961,602875,615923,616255) P ( 579) 569 134.5 1e-30 XP_016870238 (OMIM: 108961,602875,615923,616255) P ( 579) 569 134.5 1e-30 XP_011516197 (OMIM: 108961,602875,615923,616255) P ( 582) 569 134.5 1e-30 XP_016870236 (OMIM: 108961,602875,615923,616255) P ( 718) 569 134.5 1.2e-30 XP_016870235 (OMIM: 108961,602875,615923,616255) P ( 718) 569 134.5 1.2e-30 XP_011516192 (OMIM: 108961,602875,615923,616255) P ( 721) 569 134.5 1.2e-30 XP_016870234 (OMIM: 108961,602875,615923,616255) P ( 721) 569 134.5 1.2e-30 XP_011516195 (OMIM: 108961,602875,615923,616255) P ( 721) 569 134.5 1.2e-30 XP_005251536 (OMIM: 108961,602875,615923,616255) P ( 721) 569 134.5 1.2e-30 XP_011516194 (OMIM: 108961,602875,615923,616255) P ( 721) 569 134.5 1.2e-30 XP_011516193 (OMIM: 108961,602875,615923,616255) P ( 721) 569 134.5 1.2e-30 NP_003986 (OMIM: 108961,602875,615923,616255) atri (1047) 569 134.6 1.6e-30 XP_005251535 (OMIM: 108961,602875,615923,616255) P (1050) 569 134.6 1.6e-30 NP_000171 (OMIM: 204000,600179,601777) retinal gua (1103) 545 129.4 6.6e-29 XP_011522118 (OMIM: 204000,600179,601777) PREDICTE (1103) 545 129.4 6.6e-29 NP_001513 (OMIM: 300041) retinal guanylyl cyclase (1108) 537 127.6 2.2e-28 XP_011518933 (OMIM: 601330,614616,614665) PREDICTE ( 991) 514 122.6 6.7e-27 NP_004954 (OMIM: 601330,614616,614665) heat-stable (1073) 514 122.6 7.1e-27 NP_001268697 (OMIM: 103072,610154,610154) adenylat ( 338) 393 95.8 2.6e-19 XP_005249642 (OMIM: 103072,610154,610154) PREDICTE ( 563) 393 95.9 4e-19 >>NP_000848 (OMIM: 139397) guanylate cyclase soluble sub (619 aa) initn: 4107 init1: 4107 opt: 4107 Z-score: 4863.3 bits: 910.0 E(85289): 0 Smith-Waterman score: 4107; 100.0% identity (100.0% similar) in 619 aa overlap (1-619:1-619) 10 20 30 40 50 60 pF1KB4 MYGFVNHALELLVIRNYGPEVWEDIKKEAQLDEEGQFLVRIIYDDSKTYDLVAAASKVLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 MYGFVNHALELLVIRNYGPEVWEDIKKEAQLDEEGQFLVRIIYDDSKTYDLVAAASKVLN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 LNAGEILQMFGKMFFVFCQESGYDTILRVLGSNVREFLQNLDALHDHLATIYPGMRAPSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 LNAGEILQMFGKMFFVFCQESGYDTILRVLGSNVREFLQNLDALHDHLATIYPGMRAPSF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 RCTDAEKGKGLILHYYSEREGLQDIVIGIIKTVAQQIHGTEIDMKVIQQRNEECDHTQFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 RCTDAEKGKGLILHYYSEREGLQDIVIGIIKTVAQQIHGTEIDMKVIQQRNEECDHTQFL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 IEEKESKEEDFYEDLDRFEENGTQESRISPYTFCKAFPFHIIFDRDLVVTQCGNAIYRVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 IEEKESKEEDFYEDLDRFEENGTQESRISPYTFCKAFPFHIIFDRDLVVTQCGNAIYRVL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 PQLQPGNCSLLSVFSLVRPHIDISFHGILSHINTVFVLRSKEGLLDVEKLECEDELTGTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 PQLQPGNCSLLSVFSLVRPHIDISFHGILSHINTVFVLRSKEGLLDVEKLECEDELTGTE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 ISCLRLKGQMIYLPEADSILFLCSPSVMNLDDLTRRGLYLSDIPLHDATRDLVLLGEQFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 ISCLRLKGQMIYLPEADSILFLCSPSVMNLDDLTRRGLYLSDIPLHDATRDLVLLGEQFR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 EEYKLTQELEILTDRLQLTLRALEDEKKKTDTLLYSVLPPSVANELRHKRPVPAKRYDNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 EEYKLTQELEILTDRLQLTLRALEDEKKKTDTLLYSVLPPSVANELRHKRPVPAKRYDNV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB4 TILFSGIVGFNAFCSKHASGEGAMKIVNLLNDLYTRFDTLTDSRKNPFVYKVETVGDKYM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 TILFSGIVGFNAFCSKHASGEGAMKIVNLLNDLYTRFDTLTDSRKNPFVYKVETVGDKYM 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB4 TVSGLPEPCIHHARSICHLALDMMEIAGQVQVDGESVQITIGIHTGEVVTGVIGQRMPRY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 TVSGLPEPCIHHARSICHLALDMMEIAGQVQVDGESVQITIGIHTGEVVTGVIGQRMPRY 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB4 CLFGNTVNLTSRTETTGEKGKINVSEYTYRCLMSPENSDPQFHLEHRGPVSMKGKKEPMQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 CLFGNTVNLTSRTETTGEKGKINVSEYTYRCLMSPENSDPQFHLEHRGPVSMKGKKEPMQ 550 560 570 580 590 600 610 pF1KB4 VWFLSRKNTGTEETKQDDD ::::::::::::::::::: NP_000 VWFLSRKNTGTEETKQDDD 610 >>NP_001278881 (OMIM: 139397) guanylate cyclase soluble (599 aa) initn: 3927 init1: 3927 opt: 3927 Z-score: 4650.3 bits: 870.5 E(85289): 0 Smith-Waterman score: 3927; 100.0% identity (100.0% similar) in 593 aa overlap (27-619:7-599) 10 20 30 40 50 60 pF1KB4 MYGFVNHALELLVIRNYGPEVWEDIKKEAQLDEEGQFLVRIIYDDSKTYDLVAAASKVLN :::::::::::::::::::::::::::::::::: NP_001 MLMCFIKEAQLDEEGQFLVRIIYDDSKTYDLVAAASKVLN 10 20 30 40 70 80 90 100 110 120 pF1KB4 LNAGEILQMFGKMFFVFCQESGYDTILRVLGSNVREFLQNLDALHDHLATIYPGMRAPSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LNAGEILQMFGKMFFVFCQESGYDTILRVLGSNVREFLQNLDALHDHLATIYPGMRAPSF 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB4 RCTDAEKGKGLILHYYSEREGLQDIVIGIIKTVAQQIHGTEIDMKVIQQRNEECDHTQFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RCTDAEKGKGLILHYYSEREGLQDIVIGIIKTVAQQIHGTEIDMKVIQQRNEECDHTQFL 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB4 IEEKESKEEDFYEDLDRFEENGTQESRISPYTFCKAFPFHIIFDRDLVVTQCGNAIYRVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IEEKESKEEDFYEDLDRFEENGTQESRISPYTFCKAFPFHIIFDRDLVVTQCGNAIYRVL 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB4 PQLQPGNCSLLSVFSLVRPHIDISFHGILSHINTVFVLRSKEGLLDVEKLECEDELTGTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PQLQPGNCSLLSVFSLVRPHIDISFHGILSHINTVFVLRSKEGLLDVEKLECEDELTGTE 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB4 ISCLRLKGQMIYLPEADSILFLCSPSVMNLDDLTRRGLYLSDIPLHDATRDLVLLGEQFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ISCLRLKGQMIYLPEADSILFLCSPSVMNLDDLTRRGLYLSDIPLHDATRDLVLLGEQFR 290 300 310 320 330 340 370 380 390 400 410 420 pF1KB4 EEYKLTQELEILTDRLQLTLRALEDEKKKTDTLLYSVLPPSVANELRHKRPVPAKRYDNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EEYKLTQELEILTDRLQLTLRALEDEKKKTDTLLYSVLPPSVANELRHKRPVPAKRYDNV 350 360 370 380 390 400 430 440 450 460 470 480 pF1KB4 TILFSGIVGFNAFCSKHASGEGAMKIVNLLNDLYTRFDTLTDSRKNPFVYKVETVGDKYM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TILFSGIVGFNAFCSKHASGEGAMKIVNLLNDLYTRFDTLTDSRKNPFVYKVETVGDKYM 410 420 430 440 450 460 490 500 510 520 530 540 pF1KB4 TVSGLPEPCIHHARSICHLALDMMEIAGQVQVDGESVQITIGIHTGEVVTGVIGQRMPRY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TVSGLPEPCIHHARSICHLALDMMEIAGQVQVDGESVQITIGIHTGEVVTGVIGQRMPRY 470 480 490 500 510 520 550 560 570 580 590 600 pF1KB4 CLFGNTVNLTSRTETTGEKGKINVSEYTYRCLMSPENSDPQFHLEHRGPVSMKGKKEPMQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CLFGNTVNLTSRTETTGEKGKINVSEYTYRCLMSPENSDPQFHLEHRGPVSMKGKKEPMQ 530 540 550 560 570 580 610 pF1KB4 VWFLSRKNTGTEETKQDDD ::::::::::::::::::: NP_001 VWFLSRKNTGTEETKQDDD 590 >>XP_016863622 (OMIM: 139397) PREDICTED: guanylate cycla (551 aa) initn: 3671 init1: 3671 opt: 3671 Z-score: 4347.6 bits: 814.4 E(85289): 0 Smith-Waterman score: 3671; 100.0% identity (100.0% similar) in 551 aa overlap (69-619:1-551) 40 50 60 70 80 90 pF1KB4 VRIIYDDSKTYDLVAAASKVLNLNAGEILQMFGKMFFVFCQESGYDTILRVLGSNVREFL :::::::::::::::::::::::::::::: XP_016 MFGKMFFVFCQESGYDTILRVLGSNVREFL 10 20 30 100 110 120 130 140 150 pF1KB4 QNLDALHDHLATIYPGMRAPSFRCTDAEKGKGLILHYYSEREGLQDIVIGIIKTVAQQIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QNLDALHDHLATIYPGMRAPSFRCTDAEKGKGLILHYYSEREGLQDIVIGIIKTVAQQIH 40 50 60 70 80 90 160 170 180 190 200 210 pF1KB4 GTEIDMKVIQQRNEECDHTQFLIEEKESKEEDFYEDLDRFEENGTQESRISPYTFCKAFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GTEIDMKVIQQRNEECDHTQFLIEEKESKEEDFYEDLDRFEENGTQESRISPYTFCKAFP 100 110 120 130 140 150 220 230 240 250 260 270 pF1KB4 FHIIFDRDLVVTQCGNAIYRVLPQLQPGNCSLLSVFSLVRPHIDISFHGILSHINTVFVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FHIIFDRDLVVTQCGNAIYRVLPQLQPGNCSLLSVFSLVRPHIDISFHGILSHINTVFVL 160 170 180 190 200 210 280 290 300 310 320 330 pF1KB4 RSKEGLLDVEKLECEDELTGTEISCLRLKGQMIYLPEADSILFLCSPSVMNLDDLTRRGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RSKEGLLDVEKLECEDELTGTEISCLRLKGQMIYLPEADSILFLCSPSVMNLDDLTRRGL 220 230 240 250 260 270 340 350 360 370 380 390 pF1KB4 YLSDIPLHDATRDLVLLGEQFREEYKLTQELEILTDRLQLTLRALEDEKKKTDTLLYSVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YLSDIPLHDATRDLVLLGEQFREEYKLTQELEILTDRLQLTLRALEDEKKKTDTLLYSVL 280 290 300 310 320 330 400 410 420 430 440 450 pF1KB4 PPSVANELRHKRPVPAKRYDNVTILFSGIVGFNAFCSKHASGEGAMKIVNLLNDLYTRFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PPSVANELRHKRPVPAKRYDNVTILFSGIVGFNAFCSKHASGEGAMKIVNLLNDLYTRFD 340 350 360 370 380 390 460 470 480 490 500 510 pF1KB4 TLTDSRKNPFVYKVETVGDKYMTVSGLPEPCIHHARSICHLALDMMEIAGQVQVDGESVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TLTDSRKNPFVYKVETVGDKYMTVSGLPEPCIHHARSICHLALDMMEIAGQVQVDGESVQ 400 410 420 430 440 450 520 530 540 550 560 570 pF1KB4 ITIGIHTGEVVTGVIGQRMPRYCLFGNTVNLTSRTETTGEKGKINVSEYTYRCLMSPENS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ITIGIHTGEVVTGVIGQRMPRYCLFGNTVNLTSRTETTGEKGKINVSEYTYRCLMSPENS 460 470 480 490 500 510 580 590 600 610 pF1KB4 DPQFHLEHRGPVSMKGKKEPMQVWFLSRKNTGTEETKQDDD ::::::::::::::::::::::::::::::::::::::::: XP_016 DPQFHLEHRGPVSMKGKKEPMQVWFLSRKNTGTEETKQDDD 520 530 540 550 >>NP_001278884 (OMIM: 139397) guanylate cyclase soluble (551 aa) initn: 3671 init1: 3671 opt: 3671 Z-score: 4347.6 bits: 814.4 E(85289): 0 Smith-Waterman score: 3671; 100.0% identity (100.0% similar) in 551 aa overlap (69-619:1-551) 40 50 60 70 80 90 pF1KB4 VRIIYDDSKTYDLVAAASKVLNLNAGEILQMFGKMFFVFCQESGYDTILRVLGSNVREFL :::::::::::::::::::::::::::::: NP_001 MFGKMFFVFCQESGYDTILRVLGSNVREFL 10 20 30 100 110 120 130 140 150 pF1KB4 QNLDALHDHLATIYPGMRAPSFRCTDAEKGKGLILHYYSEREGLQDIVIGIIKTVAQQIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QNLDALHDHLATIYPGMRAPSFRCTDAEKGKGLILHYYSEREGLQDIVIGIIKTVAQQIH 40 50 60 70 80 90 160 170 180 190 200 210 pF1KB4 GTEIDMKVIQQRNEECDHTQFLIEEKESKEEDFYEDLDRFEENGTQESRISPYTFCKAFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GTEIDMKVIQQRNEECDHTQFLIEEKESKEEDFYEDLDRFEENGTQESRISPYTFCKAFP 100 110 120 130 140 150 220 230 240 250 260 270 pF1KB4 FHIIFDRDLVVTQCGNAIYRVLPQLQPGNCSLLSVFSLVRPHIDISFHGILSHINTVFVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FHIIFDRDLVVTQCGNAIYRVLPQLQPGNCSLLSVFSLVRPHIDISFHGILSHINTVFVL 160 170 180 190 200 210 280 290 300 310 320 330 pF1KB4 RSKEGLLDVEKLECEDELTGTEISCLRLKGQMIYLPEADSILFLCSPSVMNLDDLTRRGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RSKEGLLDVEKLECEDELTGTEISCLRLKGQMIYLPEADSILFLCSPSVMNLDDLTRRGL 220 230 240 250 260 270 340 350 360 370 380 390 pF1KB4 YLSDIPLHDATRDLVLLGEQFREEYKLTQELEILTDRLQLTLRALEDEKKKTDTLLYSVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YLSDIPLHDATRDLVLLGEQFREEYKLTQELEILTDRLQLTLRALEDEKKKTDTLLYSVL 280 290 300 310 320 330 400 410 420 430 440 450 pF1KB4 PPSVANELRHKRPVPAKRYDNVTILFSGIVGFNAFCSKHASGEGAMKIVNLLNDLYTRFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PPSVANELRHKRPVPAKRYDNVTILFSGIVGFNAFCSKHASGEGAMKIVNLLNDLYTRFD 340 350 360 370 380 390 460 470 480 490 500 510 pF1KB4 TLTDSRKNPFVYKVETVGDKYMTVSGLPEPCIHHARSICHLALDMMEIAGQVQVDGESVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TLTDSRKNPFVYKVETVGDKYMTVSGLPEPCIHHARSICHLALDMMEIAGQVQVDGESVQ 400 410 420 430 440 450 520 530 540 550 560 570 pF1KB4 ITIGIHTGEVVTGVIGQRMPRYCLFGNTVNLTSRTETTGEKGKINVSEYTYRCLMSPENS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ITIGIHTGEVVTGVIGQRMPRYCLFGNTVNLTSRTETTGEKGKINVSEYTYRCLMSPENS 460 470 480 490 500 510 580 590 600 610 pF1KB4 DPQFHLEHRGPVSMKGKKEPMQVWFLSRKNTGTEETKQDDD ::::::::::::::::::::::::::::::::::::::::: NP_001 DPQFHLEHRGPVSMKGKKEPMQVWFLSRKNTGTEETKQDDD 520 530 540 550 >>XP_016863621 (OMIM: 139397) PREDICTED: guanylate cycla (551 aa) initn: 3671 init1: 3671 opt: 3671 Z-score: 4347.6 bits: 814.4 E(85289): 0 Smith-Waterman score: 3671; 100.0% identity (100.0% similar) in 551 aa overlap (69-619:1-551) 40 50 60 70 80 90 pF1KB4 VRIIYDDSKTYDLVAAASKVLNLNAGEILQMFGKMFFVFCQESGYDTILRVLGSNVREFL :::::::::::::::::::::::::::::: XP_016 MFGKMFFVFCQESGYDTILRVLGSNVREFL 10 20 30 100 110 120 130 140 150 pF1KB4 QNLDALHDHLATIYPGMRAPSFRCTDAEKGKGLILHYYSEREGLQDIVIGIIKTVAQQIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QNLDALHDHLATIYPGMRAPSFRCTDAEKGKGLILHYYSEREGLQDIVIGIIKTVAQQIH 40 50 60 70 80 90 160 170 180 190 200 210 pF1KB4 GTEIDMKVIQQRNEECDHTQFLIEEKESKEEDFYEDLDRFEENGTQESRISPYTFCKAFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GTEIDMKVIQQRNEECDHTQFLIEEKESKEEDFYEDLDRFEENGTQESRISPYTFCKAFP 100 110 120 130 140 150 220 230 240 250 260 270 pF1KB4 FHIIFDRDLVVTQCGNAIYRVLPQLQPGNCSLLSVFSLVRPHIDISFHGILSHINTVFVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FHIIFDRDLVVTQCGNAIYRVLPQLQPGNCSLLSVFSLVRPHIDISFHGILSHINTVFVL 160 170 180 190 200 210 280 290 300 310 320 330 pF1KB4 RSKEGLLDVEKLECEDELTGTEISCLRLKGQMIYLPEADSILFLCSPSVMNLDDLTRRGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RSKEGLLDVEKLECEDELTGTEISCLRLKGQMIYLPEADSILFLCSPSVMNLDDLTRRGL 220 230 240 250 260 270 340 350 360 370 380 390 pF1KB4 YLSDIPLHDATRDLVLLGEQFREEYKLTQELEILTDRLQLTLRALEDEKKKTDTLLYSVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YLSDIPLHDATRDLVLLGEQFREEYKLTQELEILTDRLQLTLRALEDEKKKTDTLLYSVL 280 290 300 310 320 330 400 410 420 430 440 450 pF1KB4 PPSVANELRHKRPVPAKRYDNVTILFSGIVGFNAFCSKHASGEGAMKIVNLLNDLYTRFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PPSVANELRHKRPVPAKRYDNVTILFSGIVGFNAFCSKHASGEGAMKIVNLLNDLYTRFD 340 350 360 370 380 390 460 470 480 490 500 510 pF1KB4 TLTDSRKNPFVYKVETVGDKYMTVSGLPEPCIHHARSICHLALDMMEIAGQVQVDGESVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TLTDSRKNPFVYKVETVGDKYMTVSGLPEPCIHHARSICHLALDMMEIAGQVQVDGESVQ 400 410 420 430 440 450 520 530 540 550 560 570 pF1KB4 ITIGIHTGEVVTGVIGQRMPRYCLFGNTVNLTSRTETTGEKGKINVSEYTYRCLMSPENS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ITIGIHTGEVVTGVIGQRMPRYCLFGNTVNLTSRTETTGEKGKINVSEYTYRCLMSPENS 460 470 480 490 500 510 580 590 600 610 pF1KB4 DPQFHLEHRGPVSMKGKKEPMQVWFLSRKNTGTEETKQDDD ::::::::::::::::::::::::::::::::::::::::: XP_016 DPQFHLEHRGPVSMKGKKEPMQVWFLSRKNTGTEETKQDDD 520 530 540 550 >>NP_001278880 (OMIM: 139397) guanylate cyclase soluble (641 aa) initn: 3461 init1: 3461 opt: 3465 Z-score: 4102.6 bits: 769.3 E(85289): 0 Smith-Waterman score: 4053; 96.6% identity (96.6% similar) in 641 aa overlap (1-619:1-641) 10 20 30 40 50 60 pF1KB4 MYGFVNHALELLVIRNYGPEVWEDIKKEAQLDEEGQFLVRIIYDDSKTYDLVAAASKVLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MYGFVNHALELLVIRNYGPEVWEDIKKEAQLDEEGQFLVRIIYDDSKTYDLVAAASKVLN 10 20 30 40 50 60 70 80 90 pF1KB4 LNAGEILQMFGKMFFVFCQESGYDTILRVLGSNVREFLQ--------------------- ::::::::::::::::::::::::::::::::::::::: NP_001 LNAGEILQMFGKMFFVFCQESGYDTILRVLGSNVREFLQKNESKHISDLHHCFLGIYLCC 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB4 -NLDALHDHLATIYPGMRAPSFRCTDAEKGKGLILHYYSEREGLQDIVIGIIKTVAQQIH ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NNLDALHDHLATIYPGMRAPSFRCTDAEKGKGLILHYYSEREGLQDIVIGIIKTVAQQIH 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB4 GTEIDMKVIQQRNEECDHTQFLIEEKESKEEDFYEDLDRFEENGTQESRISPYTFCKAFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GTEIDMKVIQQRNEECDHTQFLIEEKESKEEDFYEDLDRFEENGTQESRISPYTFCKAFP 190 200 210 220 230 240 220 230 240 250 260 270 pF1KB4 FHIIFDRDLVVTQCGNAIYRVLPQLQPGNCSLLSVFSLVRPHIDISFHGILSHINTVFVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FHIIFDRDLVVTQCGNAIYRVLPQLQPGNCSLLSVFSLVRPHIDISFHGILSHINTVFVL 250 260 270 280 290 300 280 290 300 310 320 330 pF1KB4 RSKEGLLDVEKLECEDELTGTEISCLRLKGQMIYLPEADSILFLCSPSVMNLDDLTRRGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RSKEGLLDVEKLECEDELTGTEISCLRLKGQMIYLPEADSILFLCSPSVMNLDDLTRRGL 310 320 330 340 350 360 340 350 360 370 380 390 pF1KB4 YLSDIPLHDATRDLVLLGEQFREEYKLTQELEILTDRLQLTLRALEDEKKKTDTLLYSVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YLSDIPLHDATRDLVLLGEQFREEYKLTQELEILTDRLQLTLRALEDEKKKTDTLLYSVL 370 380 390 400 410 420 400 410 420 430 440 450 pF1KB4 PPSVANELRHKRPVPAKRYDNVTILFSGIVGFNAFCSKHASGEGAMKIVNLLNDLYTRFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PPSVANELRHKRPVPAKRYDNVTILFSGIVGFNAFCSKHASGEGAMKIVNLLNDLYTRFD 430 440 450 460 470 480 460 470 480 490 500 510 pF1KB4 TLTDSRKNPFVYKVETVGDKYMTVSGLPEPCIHHARSICHLALDMMEIAGQVQVDGESVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TLTDSRKNPFVYKVETVGDKYMTVSGLPEPCIHHARSICHLALDMMEIAGQVQVDGESVQ 490 500 510 520 530 540 520 530 540 550 560 570 pF1KB4 ITIGIHTGEVVTGVIGQRMPRYCLFGNTVNLTSRTETTGEKGKINVSEYTYRCLMSPENS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ITIGIHTGEVVTGVIGQRMPRYCLFGNTVNLTSRTETTGEKGKINVSEYTYRCLMSPENS 550 560 570 580 590 600 580 590 600 610 pF1KB4 DPQFHLEHRGPVSMKGKKEPMQVWFLSRKNTGTEETKQDDD ::::::::::::::::::::::::::::::::::::::::: NP_001 DPQFHLEHRGPVSMKGKKEPMQVWFLSRKNTGTEETKQDDD 610 620 630 640 >>NP_001278883 (OMIM: 139397) guanylate cyclase soluble (586 aa) initn: 2582 init1: 2582 opt: 2582 Z-score: 3057.1 bits: 575.7 E(85289): 1.5e-163 Smith-Waterman score: 3816; 94.7% identity (94.7% similar) in 619 aa overlap (1-619:1-586) 10 20 30 40 50 60 pF1KB4 MYGFVNHALELLVIRNYGPEVWEDIKKEAQLDEEGQFLVRIIYDDSKTYDLVAAASKVLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MYGFVNHALELLVIRNYGPEVWEDIKKEAQLDEEGQFLVRIIYDDSKTYDLVAAASKVLN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 LNAGEILQMFGKMFFVFCQESGYDTILRVLGSNVREFLQNLDALHDHLATIYPGMRAPSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LNAGEILQMFGKMFFVFCQESGYDTILRVLGSNVREFLQNLDALHDHLATIYPGMRAPSF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 RCTDAEKGKGLILHYYSEREGLQDIVIGIIKTVAQQIHGTEIDMKVIQQRNEECDHTQFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RCTDAEKGKGLILHYYSEREGLQDIVIGIIKTVAQQIHGTEIDMKVIQQRNEECDHTQFL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 IEEKESKEEDFYEDLDRFEENGTQESRISPYTFCKAFPFHIIFDRDLVVTQCGNAIYRVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IEEKESKEEDFYEDLDRFEENGTQESRISPYTFCKAFPFHIIFDRDLVVTQCGNAIYRVL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 PQLQPGNCSLLSVFSLVRPHIDISFHGILSHINTVFVLRSKEGLLDVEKLECEDELTGTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PQLQPGNCSLLSVFSLVRPHIDISFHGILSHINTVFVLRSKEGLLDVEKLECEDELTGTE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 ISCLRLKGQMIYLPEADSILFLCSPSVMNLDDLTRRGLYLSDIPLHDATRDLVLLGEQFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ISCLRLKGQMIYLPEADSILFLCSPSVMNLDDLTRRGLYLSDIPLHDATRDLVLLGEQFR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 EEYKLTQELEILTDRLQLTLRALEDEKKKTDTLLYSVLPPSVANELRHKRPVPAKRYDNV :::::::::::::::::::::::::::::::: NP_001 EEYKLTQELEILTDRLQLTLRALEDEKKKTDT---------------------------- 370 380 390 430 440 450 460 470 480 pF1KB4 TILFSGIVGFNAFCSKHASGEGAMKIVNLLNDLYTRFDTLTDSRKNPFVYKVETVGDKYM ::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 -----GIVGFNAFCSKHASGEGAMKIVNLLNDLYTRFDTLTDSRKNPFVYKVETVGDKYM 400 410 420 430 440 490 500 510 520 530 540 pF1KB4 TVSGLPEPCIHHARSICHLALDMMEIAGQVQVDGESVQITIGIHTGEVVTGVIGQRMPRY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TVSGLPEPCIHHARSICHLALDMMEIAGQVQVDGESVQITIGIHTGEVVTGVIGQRMPRY 450 460 470 480 490 500 550 560 570 580 590 600 pF1KB4 CLFGNTVNLTSRTETTGEKGKINVSEYTYRCLMSPENSDPQFHLEHRGPVSMKGKKEPMQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CLFGNTVNLTSRTETTGEKGKINVSEYTYRCLMSPENSDPQFHLEHRGPVSMKGKKEPMQ 510 520 530 540 550 560 610 pF1KB4 VWFLSRKNTGTEETKQDDD ::::::::::::::::::: NP_001 VWFLSRKNTGTEETKQDDD 570 580 >>XP_011530203 (OMIM: 139397) PREDICTED: guanylate cycla (662 aa) initn: 2582 init1: 2582 opt: 2582 Z-score: 3056.3 bits: 575.7 E(85289): 1.7e-163 Smith-Waterman score: 3939; 93.4% identity (93.4% similar) in 651 aa overlap (1-608:1-651) 10 20 30 40 50 60 pF1KB4 MYGFVNHALELLVIRNYGPEVWEDIKKEAQLDEEGQFLVRIIYDDSKTYDLVAAASKVLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MYGFVNHALELLVIRNYGPEVWEDIKKEAQLDEEGQFLVRIIYDDSKTYDLVAAASKVLN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 LNAGEILQMFGKMFFVFCQESGYDTILRVLGSNVREFLQNLDALHDHLATIYPGMRAPSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LNAGEILQMFGKMFFVFCQESGYDTILRVLGSNVREFLQNLDALHDHLATIYPGMRAPSF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 RCTDAEKGKGLILHYYSEREGLQDIVIGIIKTVAQQIHGTEIDMKVIQQRNEECDHTQFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RCTDAEKGKGLILHYYSEREGLQDIVIGIIKTVAQQIHGTEIDMKVIQQRNEECDHTQFL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 IEEKESKEEDFYEDLDRFEENGTQESRISPYTFCKAFPFHIIFDRDLVVTQCGNAIYRVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IEEKESKEEDFYEDLDRFEENGTQESRISPYTFCKAFPFHIIFDRDLVVTQCGNAIYRVL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 PQLQPGNCSLLSVFSLVRPHIDISFHGILSHINTVFVLRSKEGLLDVEKLECEDELTGTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PQLQPGNCSLLSVFSLVRPHIDISFHGILSHINTVFVLRSKEGLLDVEKLECEDELTGTE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 ISCLRLKGQMIYLPEADSILFLCSPSVMNLDDLTRRGLYLSDIPLHDATRDLVLLGEQFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ISCLRLKGQMIYLPEADSILFLCSPSVMNLDDLTRRGLYLSDIPLHDATRDLVLLGEQFR 310 320 330 340 350 360 370 380 390 pF1KB4 EEYKLTQELEILTDRLQLTLRALEDEKKKTDT---------------------------- :::::::::::::::::::::::::::::::: XP_011 EEYKLTQELEILTDRLQLTLRALEDEKKKTDTGCPARIQAFKVQTTLMLCEKDSRSTKGF 370 380 390 400 410 420 400 410 420 430 pF1KB4 ---------------LLYSVLPPSVANELRHKRPVPAKRYDNVTILFSGIVGFNAFCSKH ::::::::::::::::::::::::::::::::::::::::::::: XP_011 PSISYSGFLLIPLNRLLYSVLPPSVANELRHKRPVPAKRYDNVTILFSGIVGFNAFCSKH 430 440 450 460 470 480 440 450 460 470 480 490 pF1KB4 ASGEGAMKIVNLLNDLYTRFDTLTDSRKNPFVYKVETVGDKYMTVSGLPEPCIHHARSIC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ASGEGAMKIVNLLNDLYTRFDTLTDSRKNPFVYKVETVGDKYMTVSGLPEPCIHHARSIC 490 500 510 520 530 540 500 510 520 530 540 550 pF1KB4 HLALDMMEIAGQVQVDGESVQITIGIHTGEVVTGVIGQRMPRYCLFGNTVNLTSRTETTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HLALDMMEIAGQVQVDGESVQITIGIHTGEVVTGVIGQRMPRYCLFGNTVNLTSRTETTG 550 560 570 580 590 600 560 570 580 590 600 610 pF1KB4 EKGKINVSEYTYRCLMSPENSDPQFHLEHRGPVSMKGKKEPMQVWFLSRKNTGTEETKQD ::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EKGKINVSEYTYRCLMSPENSDPQFHLEHRGPVSMKGKKEPMQVWFLSRKNTGTEETKQD 610 620 630 640 650 660 pF1KB4 DD XP_011 DD >>XP_016863619 (OMIM: 139397) PREDICTED: guanylate cycla (594 aa) initn: 2146 init1: 2146 opt: 2146 Z-score: 2540.6 bits: 480.2 E(85289): 9e-135 Smith-Waterman score: 3503; 92.6% identity (92.6% similar) in 583 aa overlap (69-608:1-583) 40 50 60 70 80 90 pF1KB4 VRIIYDDSKTYDLVAAASKVLNLNAGEILQMFGKMFFVFCQESGYDTILRVLGSNVREFL :::::::::::::::::::::::::::::: XP_016 MFGKMFFVFCQESGYDTILRVLGSNVREFL 10 20 30 100 110 120 130 140 150 pF1KB4 QNLDALHDHLATIYPGMRAPSFRCTDAEKGKGLILHYYSEREGLQDIVIGIIKTVAQQIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QNLDALHDHLATIYPGMRAPSFRCTDAEKGKGLILHYYSEREGLQDIVIGIIKTVAQQIH 40 50 60 70 80 90 160 170 180 190 200 210 pF1KB4 GTEIDMKVIQQRNEECDHTQFLIEEKESKEEDFYEDLDRFEENGTQESRISPYTFCKAFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GTEIDMKVIQQRNEECDHTQFLIEEKESKEEDFYEDLDRFEENGTQESRISPYTFCKAFP 100 110 120 130 140 150 220 230 240 250 260 270 pF1KB4 FHIIFDRDLVVTQCGNAIYRVLPQLQPGNCSLLSVFSLVRPHIDISFHGILSHINTVFVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FHIIFDRDLVVTQCGNAIYRVLPQLQPGNCSLLSVFSLVRPHIDISFHGILSHINTVFVL 160 170 180 190 200 210 280 290 300 310 320 330 pF1KB4 RSKEGLLDVEKLECEDELTGTEISCLRLKGQMIYLPEADSILFLCSPSVMNLDDLTRRGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RSKEGLLDVEKLECEDELTGTEISCLRLKGQMIYLPEADSILFLCSPSVMNLDDLTRRGL 220 230 240 250 260 270 340 350 360 370 380 390 pF1KB4 YLSDIPLHDATRDLVLLGEQFREEYKLTQELEILTDRLQLTLRALEDEKKKTDT------ :::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YLSDIPLHDATRDLVLLGEQFREEYKLTQELEILTDRLQLTLRALEDEKKKTDTGCPARI 280 290 300 310 320 330 400 410 pF1KB4 -------------------------------------LLYSVLPPSVANELRHKRPVPAK ::::::::::::::::::::::: XP_016 QAFKVQTTLMLCEKDSRSTKGFPSISYSGFLLIPLNRLLYSVLPPSVANELRHKRPVPAK 340 350 360 370 380 390 420 430 440 450 460 470 pF1KB4 RYDNVTILFSGIVGFNAFCSKHASGEGAMKIVNLLNDLYTRFDTLTDSRKNPFVYKVETV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RYDNVTILFSGIVGFNAFCSKHASGEGAMKIVNLLNDLYTRFDTLTDSRKNPFVYKVETV 400 410 420 430 440 450 480 490 500 510 520 530 pF1KB4 GDKYMTVSGLPEPCIHHARSICHLALDMMEIAGQVQVDGESVQITIGIHTGEVVTGVIGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GDKYMTVSGLPEPCIHHARSICHLALDMMEIAGQVQVDGESVQITIGIHTGEVVTGVIGQ 460 470 480 490 500 510 540 550 560 570 580 590 pF1KB4 RMPRYCLFGNTVNLTSRTETTGEKGKINVSEYTYRCLMSPENSDPQFHLEHRGPVSMKGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RMPRYCLFGNTVNLTSRTETTGEKGKINVSEYTYRCLMSPENSDPQFHLEHRGPVSMKGK 520 530 540 550 560 570 600 610 pF1KB4 KEPMQVWFLSRKNTGTEETKQDDD ::::::::::::: XP_016 KEPMQVWFLSRKNTGTEETKQDDD 580 590 >>NP_001278882 (OMIM: 139397) guanylate cyclase soluble (594 aa) initn: 2146 init1: 2146 opt: 2146 Z-score: 2540.6 bits: 480.2 E(85289): 9e-135 Smith-Waterman score: 3503; 92.6% identity (92.6% similar) in 583 aa overlap (69-608:1-583) 40 50 60 70 80 90 pF1KB4 VRIIYDDSKTYDLVAAASKVLNLNAGEILQMFGKMFFVFCQESGYDTILRVLGSNVREFL :::::::::::::::::::::::::::::: NP_001 MFGKMFFVFCQESGYDTILRVLGSNVREFL 10 20 30 100 110 120 130 140 150 pF1KB4 QNLDALHDHLATIYPGMRAPSFRCTDAEKGKGLILHYYSEREGLQDIVIGIIKTVAQQIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QNLDALHDHLATIYPGMRAPSFRCTDAEKGKGLILHYYSEREGLQDIVIGIIKTVAQQIH 40 50 60 70 80 90 160 170 180 190 200 210 pF1KB4 GTEIDMKVIQQRNEECDHTQFLIEEKESKEEDFYEDLDRFEENGTQESRISPYTFCKAFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GTEIDMKVIQQRNEECDHTQFLIEEKESKEEDFYEDLDRFEENGTQESRISPYTFCKAFP 100 110 120 130 140 150 220 230 240 250 260 270 pF1KB4 FHIIFDRDLVVTQCGNAIYRVLPQLQPGNCSLLSVFSLVRPHIDISFHGILSHINTVFVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FHIIFDRDLVVTQCGNAIYRVLPQLQPGNCSLLSVFSLVRPHIDISFHGILSHINTVFVL 160 170 180 190 200 210 280 290 300 310 320 330 pF1KB4 RSKEGLLDVEKLECEDELTGTEISCLRLKGQMIYLPEADSILFLCSPSVMNLDDLTRRGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RSKEGLLDVEKLECEDELTGTEISCLRLKGQMIYLPEADSILFLCSPSVMNLDDLTRRGL 220 230 240 250 260 270 340 350 360 370 380 390 pF1KB4 YLSDIPLHDATRDLVLLGEQFREEYKLTQELEILTDRLQLTLRALEDEKKKTDT------ :::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YLSDIPLHDATRDLVLLGEQFREEYKLTQELEILTDRLQLTLRALEDEKKKTDTGCPARI 280 290 300 310 320 330 400 410 pF1KB4 -------------------------------------LLYSVLPPSVANELRHKRPVPAK ::::::::::::::::::::::: NP_001 QAFKVQTTLMLCEKDSRSTKGFPSISYSGFLLIPLNRLLYSVLPPSVANELRHKRPVPAK 340 350 360 370 380 390 420 430 440 450 460 470 pF1KB4 RYDNVTILFSGIVGFNAFCSKHASGEGAMKIVNLLNDLYTRFDTLTDSRKNPFVYKVETV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RYDNVTILFSGIVGFNAFCSKHASGEGAMKIVNLLNDLYTRFDTLTDSRKNPFVYKVETV 400 410 420 430 440 450 480 490 500 510 520 530 pF1KB4 GDKYMTVSGLPEPCIHHARSICHLALDMMEIAGQVQVDGESVQITIGIHTGEVVTGVIGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GDKYMTVSGLPEPCIHHARSICHLALDMMEIAGQVQVDGESVQITIGIHTGEVVTGVIGQ 460 470 480 490 500 510 540 550 560 570 580 590 pF1KB4 RMPRYCLFGNTVNLTSRTETTGEKGKINVSEYTYRCLMSPENSDPQFHLEHRGPVSMKGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RMPRYCLFGNTVNLTSRTETTGEKGKINVSEYTYRCLMSPENSDPQFHLEHRGPVSMKGK 520 530 540 550 560 570 600 610 pF1KB4 KEPMQVWFLSRKNTGTEETKQDDD ::::::::::::: NP_001 KEPMQVWFLSRKNTGTEETKQDDD 580 590 619 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 07:12:00 2016 done: Sat Nov 5 07:12:02 2016 Total Scan time: 10.200 Total Display time: 0.180 Function used was FASTA [36.3.4 Apr, 2011]