FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4155, 299 aa 1>>>pF1KB4155 299 - 299 aa - 299 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.2493+/-0.00117; mu= 6.3833+/- 0.069 mean_var=163.6167+/-34.558, 0's: 0 Z-trim(106.7): 141 B-trim: 4 in 1/50 Lambda= 0.100268 statistics sampled from 8996 (9148) to 8996 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.648), E-opt: 0.2 (0.281), width: 16 Scan time: 2.150 The best scores are: opt bits E(32554) CCDS1213.1 F11R gene_id:50848|Hs108|chr1 ( 299) 1950 294.3 7.5e-80 CCDS42911.1 JAM2 gene_id:58494|Hs108|chr21 ( 298) 563 93.7 1.9e-19 CCDS8494.2 JAM3 gene_id:83700|Hs108|chr11 ( 310) 549 91.6 7.8e-19 CCDS58787.1 JAM2 gene_id:58494|Hs108|chr21 ( 312) 528 88.6 6.4e-18 CCDS58788.1 JAM2 gene_id:58494|Hs108|chr21 ( 262) 519 87.2 1.4e-17 CCDS55799.1 JAM3 gene_id:83700|Hs108|chr11 ( 259) 372 66.0 3.5e-11 >>CCDS1213.1 F11R gene_id:50848|Hs108|chr1 (299 aa) initn: 1950 init1: 1950 opt: 1950 Z-score: 1547.1 bits: 294.3 E(32554): 7.5e-80 Smith-Waterman score: 1950; 100.0% identity (100.0% similar) in 299 aa overlap (1-299:1-299) 10 20 30 40 50 60 pF1KB4 MGTKAQVERKLLCLFILAILLCSLALGSVTVHSSEPEVRIPENNPVKLSCAYSGFSSPRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 MGTKAQVERKLLCLFILAILLCSLALGSVTVHSSEPEVRIPENNPVKLSCAYSGFSSPRV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 EWKFDQGDTTRLVCYNNKITASYEDRVTFLPTGITFKSVTREDTGTYTCMVSEEGGNSYG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 EWKFDQGDTTRLVCYNNKITASYEDRVTFLPTGITFKSVTREDTGTYTCMVSEEGGNSYG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 EVKVKLIVLVPPSKPTVNIPSSATIGNRAVLTCSEQDGSPPSEYTWFKDGIVMPTNPKST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 EVKVKLIVLVPPSKPTVNIPSSATIGNRAVLTCSEQDGSPPSEYTWFKDGIVMPTNPKST 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 RAFSNSSYVLNPTTGELVFDPLSASDTGEYSCEARNGYGTPMTSNAVRMEAVERNVGVIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 RAFSNSSYVLNPTTGELVFDPLSASDTGEYSCEARNGYGTPMTSNAVRMEAVERNVGVIV 190 200 210 220 230 240 250 260 270 280 290 pF1KB4 AAVLVTLILLGILVFGIWFAYSRGHFDRTKKGTSSKKVIYSQPSARSEGEFKQTSSFLV ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 AAVLVTLILLGILVFGIWFAYSRGHFDRTKKGTSSKKVIYSQPSARSEGEFKQTSSFLV 250 260 270 280 290 >>CCDS42911.1 JAM2 gene_id:58494|Hs108|chr21 (298 aa) initn: 417 init1: 319 opt: 563 Z-score: 462.8 bits: 93.7 E(32554): 1.9e-19 Smith-Waterman score: 563; 35.2% identity (64.5% similar) in 301 aa overlap (5-299:2-298) 10 20 30 40 50 pF1KB4 MGTKAQVERKLLCLFILAILLCSLALGSVTVHSSEPE---VRIPENNPVKLSCAYSGFS- :. :. : :..: :. .:. .. :. . : : . . :.: . CCDS42 MARRSRHRLLLLLLRYLVVALGYHKAYGFSAPKDQQVVTAVEYQEAILACKTPKKTV 10 20 30 40 50 60 70 80 90 100 110 pF1KB4 SPRVEWKFDQGDTTRLVCYNNKITASYEDRVTFLPTGITFKSVTREDTGTYTCMVSE--E : :.::: : .. .: :.. . .....:. .. .: .:.::: :.: : : :: : CCDS42 SSRLEWK-KLGRSVSFVYYQQTLQGDFKNRAEMIDFNIRIKNVTRSDAGKYRCEVSAPSE 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB4 GGNSYGEVKVKLIVLVPPSKPTVNIPSSATIGNRAVLTCSEQDGSPPSEYTWFKDGIVMP :.. : : : ::: :. :. ..:::: :. . : :....:.: ::::::::: . CCDS42 QGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVELRCQDKEGNPAPEYTWFKDGIRLL 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB4 TNPKSTRAFSNSSYVLNPTTGELVFDPLSASDTGEYSCEARNGYGTPMTSNAVRMEAVER ::. .::::..: :: : :. .: :::::::::::. : . ::.. . CCDS42 ENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEARNSVGYRRCPGK-RMQVDDL 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB4 NVGVIVAAVLVTLILLGILVFGIWFAYSRGHFDRTKKGTSSKKVIYSQPSARSEGEFKQT :.. :.:::.:. ..... .:. .: .:.: .:. . .:. :. .. ::..::.: CCDS42 NISGIIAAVVVVALVISVCGLGVCYAQRKGYF--SKETSFQKSNSSSKATTMSENDFKHT 240 250 260 270 280 290 pF1KB4 SSFLV .::.. CCDS42 KSFII >>CCDS8494.2 JAM3 gene_id:83700|Hs108|chr11 (310 aa) initn: 374 init1: 129 opt: 549 Z-score: 451.6 bits: 91.6 E(32554): 7.8e-19 Smith-Waterman score: 549; 33.6% identity (65.1% similar) in 295 aa overlap (15-299:18-310) 10 20 30 40 50 pF1KB4 MGTKAQVERKLLCLFILAILLCSLALGSVTVHSSEPEVRIPENNPVKLSCAY--SGF :.: .:. . .:.:...::. . : . :.::: : CCDS84 MALRRPPRLRLCARLPDFFLLLLFRGCLIGAVNLKSSNRTPVVQEFESVELSCIITDSQT 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB4 SSPRVEWKFDQGDTTRLVCYNNKITASYEDRVTFL-PTGITFKSVTREDTGTYTC-MVSE :.::.::: : . : : ..::: .. :. .: :.. . .:::.:.. : : .:.. CCDS84 SDPRIEWKKIQDEQTTYVFFDNKIQGDLAGRAEILGKTSLKIWNVTRRDSALYRCEVVAR 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB4 EGGNSYGEVKVKLIVLVPPSKPTVNIPSSATIGNRAVLTCSEQDGSPPSEYTWFKDGIVM . . :. ..: : : : :. .:... .:. :.: :.:..: : .:.:... . . CCDS84 NDRKEIDEIVIELTVQVKPVTPVCRVPKAVPVGKMATLHCQESEGHPRPHYSWYRNDVPL 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB4 PTNPKSTRAFSNSSYVLNPTTGELVFDPLSASDTGEYSCEARNGYGTPMTSNAVRMEAVE ::. ... : :::. :: :: ::: . .:.:.: : : : :. . .::. . CCDS84 PTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDSGQYYCIASNDAGSARCEEQ-EMEVYD 190 200 210 220 230 240 250 260 270 280 pF1KB4 RNVGVIVAAVLVTLILLGILVFGIWFAYSRGHFDRTKKGTSSKKVIYSQPSA----RS-- :.: :...:::.: .:.....:: :: ::.: .:. : : ..:.. :. CCDS84 LNIGGIIGGVLVVLAVLALITLGICCAYRRGYFINNKQDGESYKNP-GKPDGVNYIRTDE 240 250 260 270 280 290 290 pF1KB4 EGEFKQTSSFLV ::.:.. :::.. CCDS84 EGDFRHKSSFVI 300 310 >>CCDS58787.1 JAM2 gene_id:58494|Hs108|chr21 (312 aa) initn: 379 init1: 319 opt: 528 Z-score: 435.1 bits: 88.6 E(32554): 6.4e-18 Smith-Waterman score: 528; 35.9% identity (63.8% similar) in 290 aa overlap (5-282:2-287) 10 20 30 40 50 pF1KB4 MGTKAQVERKLLCLFILAILLCSLALGSVTVHS-SEPE----VRIPENNPVKLSCAYSGF :. :. : :..: :. .::: ... : :. : : . . :.: CCDS58 MARRSRHRLLLLLLRYLV--VALGYHKAYGFSAPKDQQVVTAVEYQEAILACKTPKK 10 20 30 40 50 60 70 80 90 100 110 pF1KB4 S-SPRVEWKFDQGDTTRLVCYNNKITASYEDRVTFLPTGITFKSVTREDTGTYTCMVSE- . : :.::: : .. .: :.. . .....:. .. .: .:.::: :.: : : :: CCDS58 TVSSRLEWK-KLGRSVSFVYYQQTLQGDFKNRAEMIDFNIRIKNVTRSDAGKYRCEVSAP 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB4 -EGGNSYGEVKVKLIVLVPPSKPTVNIPSSATIGNRAVLTCSEQDGSPPSEYTWFKDGIV : :.. : : : ::: :. :. ..:::: :. . : :....:.: ::::::::: CCDS58 SEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVELRCQDKEGNPAPEYTWFKDGIR 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB4 MPTNPKSTRAFSNSSYVLNPTTGELVFDPLSASDTGEYSCEARNGYGTPMTSNAVRMEAV . ::. .::::..: :: : :. .: :::::::::::. : . ::.. CCDS58 LLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEARNSVGYRRCPGK-RMQVD 180 190 200 210 220 230 240 250 260 270 280 pF1KB4 ERNVGVIVAAVLVTLILLGILVFGIWFAYSRGHFDRT----KKGTSSKKVIYSQPSARSE . :.. :.:::.:. ..... .:. .: .:.:.. :...::: . .:. CCDS58 DLNISGIIAAVVVVALVISVCGLGVCYAQRKGYFSKETSFQKSNSSSKATTMSENVQWLT 240 250 260 270 280 290 290 pF1KB4 GEFKQTSSFLV CCDS58 PVIPALWKAAAGGSRGQEF 300 310 >>CCDS58788.1 JAM2 gene_id:58494|Hs108|chr21 (262 aa) initn: 392 init1: 319 opt: 519 Z-score: 429.1 bits: 87.2 E(32554): 1.4e-17 Smith-Waterman score: 520; 38.2% identity (66.9% similar) in 251 aa overlap (51-299:26-262) 30 40 50 60 70 80 pF1KB4 LCSLALGSVTVHSSEPEVRIPENNPVKLSCAYSGFSSPRVEWKFDQGDTTRLVCYNNKIT :: :::.:. :: ... : :.. CCDS58 MARRSRHRLLLLLLRYLVVALGYHKAY-GFSAPK-----DQ-QVVTAVEYQG--- 10 20 30 40 90 100 110 120 130 pF1KB4 ASYEDRVTFLPTGITFKSVTREDTGTYTCMVSE--EGGNSYGEVKVKLIVLVPPSKPTVN ....:. .. .: .:.::: :.: : : :: : :.. : : : ::: :. :. . CCDS58 -DFKNRAEMIDFNIRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCE 50 60 70 80 90 100 140 150 160 170 180 190 pF1KB4 IPSSATIGNRAVLTCSEQDGSPPSEYTWFKDGIVMPTNPKSTRAFSNSSYVLNPTTGELV .:::: :. . : :....:.: ::::::::: . ::. .::::..: :: : CCDS58 VPSSALSGTVVELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQ 110 120 130 140 150 160 200 210 220 230 240 250 pF1KB4 FDPLSASDTGEYSCEARNGYGTPMTSNAVRMEAVERNVGVIVAAVLVTLILLGILVFGIW :. .: :::::::::::. : . ::.. . :.. :.:::.:. ..... .:. CCDS58 FNTVSKLDTGEYSCEARNSVGYRRCPGK-RMQVDDLNISGIIAAVVVVALVISVCGLGVC 170 180 190 200 210 220 260 270 280 290 pF1KB4 FAYSRGHFDRTKKGTSSKKVIYSQPSARSEGEFKQTSSFLV .: .:.: .:. . .:. :. .. ::..::.:.::.. CCDS58 YAQRKGYF--SKETSFQKSNSSSKATTMSENDFKHTKSFII 230 240 250 260 >>CCDS55799.1 JAM3 gene_id:83700|Hs108|chr11 (259 aa) initn: 391 init1: 129 opt: 372 Z-score: 314.2 bits: 66.0 E(32554): 3.5e-11 Smith-Waterman score: 389; 29.4% identity (54.6% similar) in 293 aa overlap (15-299:18-259) 10 20 30 40 50 pF1KB4 MGTKAQVERKLLCLFILAILLCSLALGSVTVHSSEPEVRIPENNPVKLSCAY--SGF :.: .:. . .:.:...::. . : . :.::: : CCDS55 MALRRPPRLRLCARLPDFFLLLLFRGCLIGAVNLKSSNRTPVVQEFESVELSCIITDSQT 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB4 SSPRVEWKFDQGDTTRLVCYNNKITASYEDRVTFLPTGITFKSVTREDTGTYTCMVSEEG :.::.::: : . : : ..::: CCDS55 SDPRIEWKKIQDEQTTYVFFDNKIQ----------------------------------- 70 80 120 130 140 150 160 170 pF1KB4 GNSYGEVKVKLIVLVPPSKPTVNIPSSATIGNRAVLTCSEQDGSPPSEYTWFKDGIVMPT : : :. .:... .:. :.: :.:..: : .:.:... . .:: CCDS55 --------------VKPVTPVCRVPKAVPVGKMATLHCQESEGHPRPHYSWYRNDVPLPT 90 100 110 120 130 180 190 200 210 220 230 pF1KB4 NPKSTRAFSNSSYVLNPTTGELVFDPLSASDTGEYSCEARNGYGTPMTSNAVRMEAVERN . ... : :::. :: :: ::: . .:.:.: : : : :. . .::. . : CCDS55 DSRANPRFRNSSFHLNSETGTLVFTAVHKDDSGQYYCIASNDAGSARCEEQ-EMEVYDLN 140 150 160 170 180 190 240 250 260 270 280 pF1KB4 VGVIVAAVLVTLILLGILVFGIWFAYSRGHFDRTKKGTSSKKVIYSQPSA----RS--EG .: :...:::.: .:.....:: :: ::.: .:. : : ..:.. :. :: CCDS55 IGGIIGGVLVVLAVLALITLGICCAYRRGYFINNKQDGESYKNP-GKPDGVNYIRTDEEG 200 210 220 230 240 290 pF1KB4 EFKQTSSFLV .:.. :::.. CCDS55 DFRHKSSFVI 250 299 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 20:49:51 2016 done: Fri Nov 4 20:49:51 2016 Total Scan time: 2.150 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]