FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4159, 145 aa 1>>>pF1KB4159 145 - 145 aa - 145 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.6342+/-0.000846; mu= 4.9331+/- 0.050 mean_var=106.3531+/-22.327, 0's: 0 Z-trim(109.2): 116 B-trim: 0 in 0/50 Lambda= 0.124365 statistics sampled from 10609 (10736) to 10609 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.707), E-opt: 0.2 (0.33), width: 16 Scan time: 1.510 The best scores are: opt bits E(32554) CCDS8678.1 LMO3 gene_id:55885|Hs108|chr12 ( 145) 1052 198.7 1e-51 CCDS58211.1 LMO3 gene_id:55885|Hs108|chr12 ( 156) 1052 198.8 1.1e-51 CCDS58212.1 LMO3 gene_id:55885|Hs108|chr12 ( 163) 1052 198.8 1.1e-51 CCDS58118.1 LMO1 gene_id:4004|Hs108|chr11 ( 155) 948 180.1 4.5e-46 CCDS44534.1 LMO1 gene_id:4004|Hs108|chr11 ( 156) 948 180.1 4.5e-46 CCDS44567.1 LMO2 gene_id:4005|Hs108|chr11 ( 158) 565 111.4 2.2e-25 CCDS7888.2 LMO2 gene_id:4005|Hs108|chr11 ( 227) 565 111.5 3e-25 CCDS58210.1 LMO3 gene_id:55885|Hs108|chr12 ( 167) 546 108.0 2.5e-24 CCDS713.1 LMO4 gene_id:8543|Hs108|chr1 ( 165) 539 106.7 5.8e-24 CCDS30962.1 LHX9 gene_id:56956|Hs108|chr1 ( 388) 451 91.2 6.7e-19 CCDS1393.1 LHX9 gene_id:56956|Hs108|chr1 ( 397) 451 91.2 6.8e-19 CCDS6853.1 LHX2 gene_id:9355|Hs108|chr9 ( 406) 425 86.5 1.8e-17 CCDS1338.1 LHX4 gene_id:89884|Hs108|chr1 ( 390) 424 86.3 1.9e-17 CCDS6994.1 LHX3 gene_id:8022|Hs108|chr9 ( 397) 412 84.2 8.7e-17 CCDS6995.1 LHX3 gene_id:8022|Hs108|chr9 ( 402) 412 84.2 8.8e-17 CCDS1247.1 LMX1A gene_id:4009|Hs108|chr1 ( 382) 378 78.0 5.8e-15 CCDS10290.1 ISL2 gene_id:64843|Hs108|chr15 ( 359) 377 77.9 6.2e-15 CCDS6866.2 LMX1B gene_id:4010|Hs108|chr9 ( 395) 373 77.2 1.1e-14 CCDS55342.1 LMX1B gene_id:4010|Hs108|chr9 ( 402) 373 77.2 1.1e-14 CCDS55343.1 LMX1B gene_id:4010|Hs108|chr9 ( 406) 373 77.2 1.1e-14 CCDS11316.1 LHX1 gene_id:3975|Hs108|chr17 ( 406) 371 76.8 1.4e-14 CCDS9171.1 LHX5 gene_id:64211|Hs108|chr12 ( 402) 360 74.8 5.6e-14 CCDS43314.1 ISL1 gene_id:3670|Hs108|chr5 ( 349) 357 74.3 7.3e-14 CCDS58008.1 LHX8 gene_id:431707|Hs108|chr1 ( 346) 340 71.2 6e-13 CCDS30756.1 LHX8 gene_id:431707|Hs108|chr1 ( 356) 340 71.2 6.1e-13 CCDS56583.1 LHX6 gene_id:26468|Hs108|chr9 ( 363) 334 70.1 1.3e-12 CCDS56584.1 LHX6 gene_id:26468|Hs108|chr9 ( 366) 334 70.1 1.3e-12 CCDS6837.2 LHX6 gene_id:26468|Hs108|chr9 ( 377) 334 70.2 1.4e-12 CCDS6838.2 LHX6 gene_id:26468|Hs108|chr9 ( 392) 334 70.2 1.4e-12 >>CCDS8678.1 LMO3 gene_id:55885|Hs108|chr12 (145 aa) initn: 1052 init1: 1052 opt: 1052 Z-score: 1041.9 bits: 198.7 E(32554): 1e-51 Smith-Waterman score: 1052; 100.0% identity (100.0% similar) in 145 aa overlap (1-145:1-145) 10 20 30 40 50 60 pF1KB4 MLSVQPDTKPKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEVGSTLYTKANL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS86 MLSVQPDTKPKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEVGSTLYTKANL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 ILCRRDYLRLFGVTGNCAACSKLIPAFEMVMRAKDNVYHLDCFACQLCNQRFCVGDKFFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS86 ILCRRDYLRLFGVTGNCAACSKLIPAFEMVMRAKDNVYHLDCFACQLCNQRFCVGDKFFL 70 80 90 100 110 120 130 140 pF1KB4 KNNMILCQTDYEEGLMKEGYAPQVR ::::::::::::::::::::::::: CCDS86 KNNMILCQTDYEEGLMKEGYAPQVR 130 140 >>CCDS58211.1 LMO3 gene_id:55885|Hs108|chr12 (156 aa) initn: 1052 init1: 1052 opt: 1052 Z-score: 1041.5 bits: 198.8 E(32554): 1.1e-51 Smith-Waterman score: 1052; 100.0% identity (100.0% similar) in 145 aa overlap (1-145:12-156) 10 20 30 40 pF1KB4 MLSVQPDTKPKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGE ::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 MQKKEKSFGIQMLSVQPDTKPKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGE 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB4 VGSTLYTKANLILCRRDYLRLFGVTGNCAACSKLIPAFEMVMRAKDNVYHLDCFACQLCN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 VGSTLYTKANLILCRRDYLRLFGVTGNCAACSKLIPAFEMVMRAKDNVYHLDCFACQLCN 70 80 90 100 110 120 110 120 130 140 pF1KB4 QRFCVGDKFFLKNNMILCQTDYEEGLMKEGYAPQVR :::::::::::::::::::::::::::::::::::: CCDS58 QRFCVGDKFFLKNNMILCQTDYEEGLMKEGYAPQVR 130 140 150 >>CCDS58212.1 LMO3 gene_id:55885|Hs108|chr12 (163 aa) initn: 1052 init1: 1052 opt: 1052 Z-score: 1041.2 bits: 198.8 E(32554): 1.1e-51 Smith-Waterman score: 1052; 100.0% identity (100.0% similar) in 145 aa overlap (1-145:19-163) 10 20 30 40 pF1KB4 MLSVQPDTKPKGCAGCNRKIKDRYLLKALDKYWHEDCLKCAC :::::::::::::::::::::::::::::::::::::::::: CCDS58 MLMEGGRAAAARNVSSIQMLSVQPDTKPKGCAGCNRKIKDRYLLKALDKYWHEDCLKCAC 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB4 CDCRLGEVGSTLYTKANLILCRRDYLRLFGVTGNCAACSKLIPAFEMVMRAKDNVYHLDC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 CDCRLGEVGSTLYTKANLILCRRDYLRLFGVTGNCAACSKLIPAFEMVMRAKDNVYHLDC 70 80 90 100 110 120 110 120 130 140 pF1KB4 FACQLCNQRFCVGDKFFLKNNMILCQTDYEEGLMKEGYAPQVR ::::::::::::::::::::::::::::::::::::::::::: CCDS58 FACQLCNQRFCVGDKFFLKNNMILCQTDYEEGLMKEGYAPQVR 130 140 150 160 >>CCDS58118.1 LMO1 gene_id:4004|Hs108|chr11 (155 aa) initn: 1053 init1: 948 opt: 948 Z-score: 940.7 bits: 180.1 E(32554): 4.5e-46 Smith-Waterman score: 948; 89.7% identity (93.8% similar) in 145 aa overlap (1-145:11-155) 10 20 30 40 50 pF1KB4 MLSVQPDTKPKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEV :::::: : :::::::::::::::::::::::::::::::::::::::: CCDS58 MVLDQEDGVPMLSVQPKGKQKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEV 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB4 GSTLYTKANLILCRRDYLRLFGVTGNCAACSKLIPAFEMVMRAKDNVYHLDCFACQLCNQ ::::::::::::::::::::::.::::::::::::::::::::.:::::::::::::::: CCDS58 GSTLYTKANLILCRRDYLRLFGTTGNCAACSKLIPAFEMVMRARDNVYHLDCFACQLCNQ 70 80 90 100 110 120 120 130 140 pF1KB4 RFCVGDKFFLKNNMILCQTDYEEGLMKEGYAPQVR :::::::::::::::::: ::::: .. . ::. CCDS58 RFCVGDKFFLKNNMILCQMDYEEGQLNGTFESQVQ 130 140 150 >>CCDS44534.1 LMO1 gene_id:4004|Hs108|chr11 (156 aa) initn: 1053 init1: 948 opt: 948 Z-score: 940.6 bits: 180.1 E(32554): 4.5e-46 Smith-Waterman score: 948; 89.7% identity (93.8% similar) in 145 aa overlap (1-145:12-156) 10 20 30 40 pF1KB4 MLSVQPDTKPKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGE :::::: : ::::::::::::::::::::::::::::::::::::::: CCDS44 MMVLDKEDGVPMLSVQPKGKQKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGE 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB4 VGSTLYTKANLILCRRDYLRLFGVTGNCAACSKLIPAFEMVMRAKDNVYHLDCFACQLCN :::::::::::::::::::::::.::::::::::::::::::::.::::::::::::::: CCDS44 VGSTLYTKANLILCRRDYLRLFGTTGNCAACSKLIPAFEMVMRARDNVYHLDCFACQLCN 70 80 90 100 110 120 110 120 130 140 pF1KB4 QRFCVGDKFFLKNNMILCQTDYEEGLMKEGYAPQVR ::::::::::::::::::: ::::: .. . ::. CCDS44 QRFCVGDKFFLKNNMILCQMDYEEGQLNGTFESQVQ 130 140 150 >>CCDS44567.1 LMO2 gene_id:4005|Hs108|chr11 (158 aa) initn: 640 init1: 552 opt: 565 Z-score: 569.2 bits: 111.4 E(32554): 2.2e-25 Smith-Waterman score: 565; 60.3% identity (81.0% similar) in 121 aa overlap (13-133:30-150) 10 20 30 40 pF1KB4 MLSVQPDTKPKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACC :.::...: :::.:::.:.:::::::.: : CCDS44 MSSAIERKSLDPSEEPVDEVLQIPPSLLTCGGCQQNIGDRYFLKAIDQYWHEDCLSCDLC 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB4 DCRLGEVGSTLYTKANLILCRRDYLRLFGVTGNCAACSKLIPAFEMVMRAKDNVYHLDCF ::::::: :: : . ::::::::::: : ::.:.: : :.::.::.::.::::.:: CCDS44 GCRLGEVGRRLYYKLGRKLCRRDYLRLFGQDGLCASCDKRIRAYEMTMRVKDKVYHLECF 70 80 90 100 110 120 110 120 130 140 pF1KB4 ACQLCNQRFCVGDKFFLKNNMILCQTDYEEGLMKEGYAPQVR : :...:::::...: :. :.:. : : CCDS44 KCAACQKHFCVGDRYLLINSDIVCEQDIYEWTKINGMI 130 140 150 >>CCDS7888.2 LMO2 gene_id:4005|Hs108|chr11 (227 aa) initn: 640 init1: 552 opt: 565 Z-score: 566.8 bits: 111.5 E(32554): 3e-25 Smith-Waterman score: 565; 60.3% identity (81.0% similar) in 121 aa overlap (13-133:99-219) 10 20 30 40 pF1KB4 MLSVQPDTKPKGCAGCNRKIKDRYLLKALDKYWHEDCLKCAC :.::...: :::.:::.:.:::::::.: CCDS78 PMSSAIERKSLDPSEEPVDEVLQIPPSLLTCGGCQQNIGDRYFLKAIDQYWHEDCLSCDL 70 80 90 100 110 120 50 60 70 80 90 100 pF1KB4 CDCRLGEVGSTLYTKANLILCRRDYLRLFGVTGNCAACSKLIPAFEMVMRAKDNVYHLDC : ::::::: :: : . ::::::::::: : ::.:.: : :.::.::.::.::::.: CCDS78 CGCRLGEVGRRLYYKLGRKLCRRDYLRLFGQDGLCASCDKRIRAYEMTMRVKDKVYHLEC 130 140 150 160 170 180 110 120 130 140 pF1KB4 FACQLCNQRFCVGDKFFLKNNMILCQTDYEEGLMKEGYAPQVR : : :...:::::...: :. :.:. : : CCDS78 FKCAACQKHFCVGDRYLLINSDIVCEQDIYEWTKINGMI 190 200 210 220 >>CCDS58210.1 LMO3 gene_id:55885|Hs108|chr12 (167 aa) initn: 909 init1: 546 opt: 546 Z-score: 550.4 bits: 108.0 E(32554): 2.5e-24 Smith-Waterman score: 870; 78.0% identity (82.1% similar) in 168 aa overlap (1-145:1-167) 10 20 30 40 50 pF1KB4 MLSVQPDTKPKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGE----VGSTLYT ::::::::::::::::::::::::::::::::::::::::::::::::: :: .: CCDS58 MLSVQPDTKPKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEHLKRCGS-IYI 10 20 30 40 50 60 70 80 90 pF1KB4 KA---NLILCRR----------DYLR------LFGVTGNCAACSKLIPAFEMVMRAKDNV .: .. .: :. . :::::::::::::::::::::::::::: CCDS58 HAAHTEIGICVTLEWPLPFVIIDFSQQITIAWLFGVTGNCAACSKLIPAFEMVMRAKDNV 60 70 80 90 100 110 100 110 120 130 140 pF1KB4 YHLDCFACQLCNQRFCVGDKFFLKNNMILCQTDYEEGLMKEGYAPQVR :::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 YHLDCFACQLCNQRFCVGDKFFLKNNMILCQTDYEEGLMKEGYAPQVR 120 130 140 150 160 >>CCDS713.1 LMO4 gene_id:8543|Hs108|chr1 (165 aa) initn: 546 init1: 508 opt: 539 Z-score: 543.7 bits: 106.7 E(32554): 5.8e-24 Smith-Waterman score: 539; 53.2% identity (78.6% similar) in 126 aa overlap (11-136:21-146) 10 20 30 40 50 pF1KB4 MLSVQPDTKPKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEV : ::::. :: ::.:: :.:.::: ::::.::. .::.. CCDS71 MVNPGSSSQPPPVTAGSLSWKRCAGCGGKIADRFLLYAMDSYWHSRCLKCSCCQAQLGDI 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB4 GSTLYTKANLILCRRDYLRLFGVTGNCAACSKLIPAFEMVMRAKDNVYHLDCFACQLCNQ :.. :::...:::: ::.:::: .: :.::.. ::: :.::::. ::::: ::.:. : . CCDS71 GTSCYTKSGMILCRNDYIRLFGNSGACSACGQSIPASELVMRAQGNVYHLKCFTCSTCRN 70 80 90 100 110 120 120 130 140 pF1KB4 RFCVGDKFFLKNNMILCQTDYEEGLMKEGYAPQVR :. ::.: :. ..:. : .:. CCDS71 RLVPGDRFHYINGSLFCEHDRPTALINGHLNSLQSNPLLPDQKVC 130 140 150 160 >>CCDS30962.1 LHX9 gene_id:56956|Hs108|chr1 (388 aa) initn: 404 init1: 227 opt: 451 Z-score: 452.8 bits: 91.2 E(32554): 6.7e-19 Smith-Waterman score: 451; 46.9% identity (70.3% similar) in 145 aa overlap (1-144:51-190) 10 20 30 pF1KB4 MLSVQPDTKPKGCAGCNRKIKDRYLLKALD : ..:. :: ::::. ::.::: : :.: CCDS30 IQGIMEEMERRSKTEARLAKGAQLNGRDAGMPPLSPE-KPALCAGCGGKISDRYYLLAVD 30 40 50 60 70 40 50 60 70 80 pF1KB4 KYWHEDCLKCACCDCRLG-EVGSTLYTKANLILCRRDYLRLFGVTGNCAACSKLIPAFEM : :: :::: :.:.:. : : ..: . : :..:: : :.: :: : : : :: CCDS30 KQWHLRCLKC--CECKLALESELTCFAKDGSIYCKEDYYRRFSVQ-RCARCHLGISASEM 80 90 100 110 120 130 90 100 110 120 130 140 pF1KB4 VMRAKDNVYHLDCFACQLCNQRFCVGDKFFLKNNMILCQTDYEEGLMKEGYAPQVR ::::.:.::::.::.:. ::. . .::.: .:.... :.. .: :. : : ::. CCDS30 VMRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDSLVYCRAHFETLLQGE-YPPQLSYTEL 140 150 160 170 180 190 CCDS30 AAKSGGLALPYFNGTGTVQKGRPRKRKSPALGVDIVNYNSGCNENEADHLDRDQQPYPPS 200 210 220 230 240 250 145 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 21:30:24 2016 done: Thu Nov 3 21:30:24 2016 Total Scan time: 1.510 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]