FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4159, 145 aa 1>>>pF1KB4159 145 - 145 aa - 145 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.7121+/-0.00039; mu= 10.2825+/- 0.024 mean_var=132.3331+/-30.548, 0's: 0 Z-trim(115.9): 316 B-trim: 1142 in 1/49 Lambda= 0.111491 statistics sampled from 26192 (26633) to 26192 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.686), E-opt: 0.2 (0.312), width: 16 Scan time: 4.780 The best scores are: opt bits E(85289) NP_001230538 (OMIM: 180386) LIM domain only protei ( 145) 1052 179.9 1.3e-45 XP_011519064 (OMIM: 180386) PREDICTED: LIM domain ( 145) 1052 179.9 1.3e-45 XP_006719173 (OMIM: 180386) PREDICTED: LIM domain ( 145) 1052 179.9 1.3e-45 NP_001230539 (OMIM: 180386) LIM domain only protei ( 145) 1052 179.9 1.3e-45 NP_061110 (OMIM: 180386) LIM domain only protein 3 ( 145) 1052 179.9 1.3e-45 XP_006719174 (OMIM: 180386) PREDICTED: LIM domain ( 145) 1052 179.9 1.3e-45 XP_011519065 (OMIM: 180386) PREDICTED: LIM domain ( 145) 1052 179.9 1.3e-45 NP_001001395 (OMIM: 180386) LIM domain only protei ( 145) 1052 179.9 1.3e-45 NP_001230540 (OMIM: 180386) LIM domain only protei ( 156) 1052 179.9 1.4e-45 NP_001230541 (OMIM: 180386) LIM domain only protei ( 163) 1052 179.9 1.4e-45 XP_011518401 (OMIM: 186921) PREDICTED: rhombotin-1 ( 145) 948 163.1 1.4e-40 XP_011518400 (OMIM: 186921) PREDICTED: rhombotin-1 ( 145) 948 163.1 1.4e-40 NP_001257357 (OMIM: 186921) rhombotin-1 isoform b ( 155) 948 163.2 1.5e-40 NP_002306 (OMIM: 186921) rhombotin-1 isoform a [Ho ( 156) 948 163.2 1.5e-40 XP_006718291 (OMIM: 186921) PREDICTED: rhombotin-1 ( 193) 948 163.3 1.7e-40 XP_016873219 (OMIM: 180385) PREDICTED: rhombotin-2 ( 158) 565 101.6 5.2e-22 NP_001135788 (OMIM: 180385) rhombotin-2 isoform 2 ( 158) 565 101.6 5.2e-22 XP_016873217 (OMIM: 180385) PREDICTED: rhombotin-2 ( 158) 565 101.6 5.2e-22 XP_005252978 (OMIM: 180385) PREDICTED: rhombotin-2 ( 158) 565 101.6 5.2e-22 XP_016873218 (OMIM: 180385) PREDICTED: rhombotin-2 ( 158) 565 101.6 5.2e-22 XP_016873222 (OMIM: 180385) PREDICTED: rhombotin-2 ( 158) 565 101.6 5.2e-22 NP_001135787 (OMIM: 180385) rhombotin-2 isoform 2 ( 158) 565 101.6 5.2e-22 XP_016873216 (OMIM: 180385) PREDICTED: rhombotin-2 ( 158) 565 101.6 5.2e-22 XP_016873221 (OMIM: 180385) PREDICTED: rhombotin-2 ( 158) 565 101.6 5.2e-22 XP_016873220 (OMIM: 180385) PREDICTED: rhombotin-2 ( 158) 565 101.6 5.2e-22 NP_005565 (OMIM: 180385) rhombotin-2 isoform 1 [Ho ( 227) 565 101.8 6.5e-22 XP_016875132 (OMIM: 180386) PREDICTED: LIM domain ( 125) 546 98.4 3.7e-21 NP_001230542 (OMIM: 180386) LIM domain only protei ( 167) 546 98.5 4.5e-21 XP_005271348 (OMIM: 603129) PREDICTED: LIM domain ( 165) 539 97.4 9.7e-21 NP_006760 (OMIM: 603129) LIM domain transcription ( 165) 539 97.4 9.7e-21 XP_011518402 (OMIM: 186921) PREDICTED: rhombotin-1 ( 122) 476 87.1 9e-18 XP_005245407 (OMIM: 606066) PREDICTED: LIM/homeobo ( 336) 451 83.6 2.8e-16 XP_016857338 (OMIM: 606066) PREDICTED: LIM/homeobo ( 378) 451 83.7 3e-16 NP_001014434 (OMIM: 606066) LIM/homeobox protein L ( 388) 451 83.7 3e-16 NP_064589 (OMIM: 606066) LIM/homeobox protein Lhx9 ( 397) 451 83.7 3.1e-16 XP_011508083 (OMIM: 606066) PREDICTED: LIM/homeobo ( 403) 451 83.7 3.1e-16 XP_006717386 (OMIM: 603759) PREDICTED: LIM/homeobo ( 314) 425 79.4 4.8e-15 NP_004780 (OMIM: 603759) LIM/homeobox protein Lhx2 ( 406) 425 79.5 5.7e-15 NP_203129 (OMIM: 262700,602146) LIM/homeobox prote ( 390) 424 79.4 6.2e-15 XP_016870657 (OMIM: 221750,600577) PREDICTED: LIM/ ( 373) 412 77.4 2.3e-14 XP_005263467 (OMIM: 221750,600577) PREDICTED: LIM/ ( 386) 412 77.4 2.3e-14 NP_835258 (OMIM: 221750,600577) LIM/homeobox prote ( 397) 412 77.4 2.4e-14 NP_055379 (OMIM: 221750,600577) LIM/homeobox prote ( 402) 412 77.4 2.4e-14 XP_011507842 (OMIM: 600298) PREDICTED: LIM homeobo ( 279) 378 71.8 8.5e-13 NP_001167540 (OMIM: 600298) LIM homeobox transcrip ( 382) 378 72.0 1e-12 NP_796372 (OMIM: 600298) LIM homeobox transcriptio ( 382) 378 72.0 1e-12 NP_665804 (OMIM: 609481) insulin gene enhancer pro ( 359) 377 71.8 1.1e-12 XP_016877994 (OMIM: 609481) PREDICTED: insulin gen ( 534) 377 72.0 1.4e-12 NP_002307 (OMIM: 161200,602575) LIM homeobox trans ( 395) 373 71.2 1.8e-12 NP_001167618 (OMIM: 161200,602575) LIM homeobox tr ( 402) 373 71.2 1.9e-12 >>NP_001230538 (OMIM: 180386) LIM domain only protein 3 (145 aa) initn: 1052 init1: 1052 opt: 1052 Z-score: 939.9 bits: 179.9 E(85289): 1.3e-45 Smith-Waterman score: 1052; 100.0% identity (100.0% similar) in 145 aa overlap (1-145:1-145) 10 20 30 40 50 60 pF1KB4 MLSVQPDTKPKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEVGSTLYTKANL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MLSVQPDTKPKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEVGSTLYTKANL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 ILCRRDYLRLFGVTGNCAACSKLIPAFEMVMRAKDNVYHLDCFACQLCNQRFCVGDKFFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ILCRRDYLRLFGVTGNCAACSKLIPAFEMVMRAKDNVYHLDCFACQLCNQRFCVGDKFFL 70 80 90 100 110 120 130 140 pF1KB4 KNNMILCQTDYEEGLMKEGYAPQVR ::::::::::::::::::::::::: NP_001 KNNMILCQTDYEEGLMKEGYAPQVR 130 140 >>XP_011519064 (OMIM: 180386) PREDICTED: LIM domain only (145 aa) initn: 1052 init1: 1052 opt: 1052 Z-score: 939.9 bits: 179.9 E(85289): 1.3e-45 Smith-Waterman score: 1052; 100.0% identity (100.0% similar) in 145 aa overlap (1-145:1-145) 10 20 30 40 50 60 pF1KB4 MLSVQPDTKPKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEVGSTLYTKANL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MLSVQPDTKPKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEVGSTLYTKANL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 ILCRRDYLRLFGVTGNCAACSKLIPAFEMVMRAKDNVYHLDCFACQLCNQRFCVGDKFFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ILCRRDYLRLFGVTGNCAACSKLIPAFEMVMRAKDNVYHLDCFACQLCNQRFCVGDKFFL 70 80 90 100 110 120 130 140 pF1KB4 KNNMILCQTDYEEGLMKEGYAPQVR ::::::::::::::::::::::::: XP_011 KNNMILCQTDYEEGLMKEGYAPQVR 130 140 >>XP_006719173 (OMIM: 180386) PREDICTED: LIM domain only (145 aa) initn: 1052 init1: 1052 opt: 1052 Z-score: 939.9 bits: 179.9 E(85289): 1.3e-45 Smith-Waterman score: 1052; 100.0% identity (100.0% similar) in 145 aa overlap (1-145:1-145) 10 20 30 40 50 60 pF1KB4 MLSVQPDTKPKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEVGSTLYTKANL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MLSVQPDTKPKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEVGSTLYTKANL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 ILCRRDYLRLFGVTGNCAACSKLIPAFEMVMRAKDNVYHLDCFACQLCNQRFCVGDKFFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ILCRRDYLRLFGVTGNCAACSKLIPAFEMVMRAKDNVYHLDCFACQLCNQRFCVGDKFFL 70 80 90 100 110 120 130 140 pF1KB4 KNNMILCQTDYEEGLMKEGYAPQVR ::::::::::::::::::::::::: XP_006 KNNMILCQTDYEEGLMKEGYAPQVR 130 140 >>NP_001230539 (OMIM: 180386) LIM domain only protein 3 (145 aa) initn: 1052 init1: 1052 opt: 1052 Z-score: 939.9 bits: 179.9 E(85289): 1.3e-45 Smith-Waterman score: 1052; 100.0% identity (100.0% similar) in 145 aa overlap (1-145:1-145) 10 20 30 40 50 60 pF1KB4 MLSVQPDTKPKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEVGSTLYTKANL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MLSVQPDTKPKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEVGSTLYTKANL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 ILCRRDYLRLFGVTGNCAACSKLIPAFEMVMRAKDNVYHLDCFACQLCNQRFCVGDKFFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ILCRRDYLRLFGVTGNCAACSKLIPAFEMVMRAKDNVYHLDCFACQLCNQRFCVGDKFFL 70 80 90 100 110 120 130 140 pF1KB4 KNNMILCQTDYEEGLMKEGYAPQVR ::::::::::::::::::::::::: NP_001 KNNMILCQTDYEEGLMKEGYAPQVR 130 140 >>NP_061110 (OMIM: 180386) LIM domain only protein 3 iso (145 aa) initn: 1052 init1: 1052 opt: 1052 Z-score: 939.9 bits: 179.9 E(85289): 1.3e-45 Smith-Waterman score: 1052; 100.0% identity (100.0% similar) in 145 aa overlap (1-145:1-145) 10 20 30 40 50 60 pF1KB4 MLSVQPDTKPKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEVGSTLYTKANL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 MLSVQPDTKPKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEVGSTLYTKANL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 ILCRRDYLRLFGVTGNCAACSKLIPAFEMVMRAKDNVYHLDCFACQLCNQRFCVGDKFFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 ILCRRDYLRLFGVTGNCAACSKLIPAFEMVMRAKDNVYHLDCFACQLCNQRFCVGDKFFL 70 80 90 100 110 120 130 140 pF1KB4 KNNMILCQTDYEEGLMKEGYAPQVR ::::::::::::::::::::::::: NP_061 KNNMILCQTDYEEGLMKEGYAPQVR 130 140 >>XP_006719174 (OMIM: 180386) PREDICTED: LIM domain only (145 aa) initn: 1052 init1: 1052 opt: 1052 Z-score: 939.9 bits: 179.9 E(85289): 1.3e-45 Smith-Waterman score: 1052; 100.0% identity (100.0% similar) in 145 aa overlap (1-145:1-145) 10 20 30 40 50 60 pF1KB4 MLSVQPDTKPKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEVGSTLYTKANL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MLSVQPDTKPKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEVGSTLYTKANL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 ILCRRDYLRLFGVTGNCAACSKLIPAFEMVMRAKDNVYHLDCFACQLCNQRFCVGDKFFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ILCRRDYLRLFGVTGNCAACSKLIPAFEMVMRAKDNVYHLDCFACQLCNQRFCVGDKFFL 70 80 90 100 110 120 130 140 pF1KB4 KNNMILCQTDYEEGLMKEGYAPQVR ::::::::::::::::::::::::: XP_006 KNNMILCQTDYEEGLMKEGYAPQVR 130 140 >>XP_011519065 (OMIM: 180386) PREDICTED: LIM domain only (145 aa) initn: 1052 init1: 1052 opt: 1052 Z-score: 939.9 bits: 179.9 E(85289): 1.3e-45 Smith-Waterman score: 1052; 100.0% identity (100.0% similar) in 145 aa overlap (1-145:1-145) 10 20 30 40 50 60 pF1KB4 MLSVQPDTKPKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEVGSTLYTKANL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MLSVQPDTKPKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEVGSTLYTKANL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 ILCRRDYLRLFGVTGNCAACSKLIPAFEMVMRAKDNVYHLDCFACQLCNQRFCVGDKFFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ILCRRDYLRLFGVTGNCAACSKLIPAFEMVMRAKDNVYHLDCFACQLCNQRFCVGDKFFL 70 80 90 100 110 120 130 140 pF1KB4 KNNMILCQTDYEEGLMKEGYAPQVR ::::::::::::::::::::::::: XP_011 KNNMILCQTDYEEGLMKEGYAPQVR 130 140 >>NP_001001395 (OMIM: 180386) LIM domain only protein 3 (145 aa) initn: 1052 init1: 1052 opt: 1052 Z-score: 939.9 bits: 179.9 E(85289): 1.3e-45 Smith-Waterman score: 1052; 100.0% identity (100.0% similar) in 145 aa overlap (1-145:1-145) 10 20 30 40 50 60 pF1KB4 MLSVQPDTKPKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEVGSTLYTKANL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MLSVQPDTKPKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEVGSTLYTKANL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 ILCRRDYLRLFGVTGNCAACSKLIPAFEMVMRAKDNVYHLDCFACQLCNQRFCVGDKFFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ILCRRDYLRLFGVTGNCAACSKLIPAFEMVMRAKDNVYHLDCFACQLCNQRFCVGDKFFL 70 80 90 100 110 120 130 140 pF1KB4 KNNMILCQTDYEEGLMKEGYAPQVR ::::::::::::::::::::::::: NP_001 KNNMILCQTDYEEGLMKEGYAPQVR 130 140 >>NP_001230540 (OMIM: 180386) LIM domain only protein 3 (156 aa) initn: 1052 init1: 1052 opt: 1052 Z-score: 939.6 bits: 179.9 E(85289): 1.4e-45 Smith-Waterman score: 1052; 100.0% identity (100.0% similar) in 145 aa overlap (1-145:12-156) 10 20 30 40 pF1KB4 MLSVQPDTKPKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGE ::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MQKKEKSFGIQMLSVQPDTKPKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGE 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB4 VGSTLYTKANLILCRRDYLRLFGVTGNCAACSKLIPAFEMVMRAKDNVYHLDCFACQLCN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VGSTLYTKANLILCRRDYLRLFGVTGNCAACSKLIPAFEMVMRAKDNVYHLDCFACQLCN 70 80 90 100 110 120 110 120 130 140 pF1KB4 QRFCVGDKFFLKNNMILCQTDYEEGLMKEGYAPQVR :::::::::::::::::::::::::::::::::::: NP_001 QRFCVGDKFFLKNNMILCQTDYEEGLMKEGYAPQVR 130 140 150 >>NP_001230541 (OMIM: 180386) LIM domain only protein 3 (163 aa) initn: 1052 init1: 1052 opt: 1052 Z-score: 939.3 bits: 179.9 E(85289): 1.4e-45 Smith-Waterman score: 1052; 100.0% identity (100.0% similar) in 145 aa overlap (1-145:19-163) 10 20 30 40 pF1KB4 MLSVQPDTKPKGCAGCNRKIKDRYLLKALDKYWHEDCLKCAC :::::::::::::::::::::::::::::::::::::::::: NP_001 MLMEGGRAAAARNVSSIQMLSVQPDTKPKGCAGCNRKIKDRYLLKALDKYWHEDCLKCAC 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB4 CDCRLGEVGSTLYTKANLILCRRDYLRLFGVTGNCAACSKLIPAFEMVMRAKDNVYHLDC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CDCRLGEVGSTLYTKANLILCRRDYLRLFGVTGNCAACSKLIPAFEMVMRAKDNVYHLDC 70 80 90 100 110 120 110 120 130 140 pF1KB4 FACQLCNQRFCVGDKFFLKNNMILCQTDYEEGLMKEGYAPQVR ::::::::::::::::::::::::::::::::::::::::::: NP_001 FACQLCNQRFCVGDKFFLKNNMILCQTDYEEGLMKEGYAPQVR 130 140 150 160 145 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 21:30:24 2016 done: Thu Nov 3 21:30:25 2016 Total Scan time: 4.780 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]