FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4165, 826 aa 1>>>pF1KB4165 826 - 826 aa - 826 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 10.1639+/-0.000481; mu= -0.1879+/- 0.030 mean_var=379.4098+/-75.707, 0's: 0 Z-trim(119.0): 277 B-trim: 63 in 1/57 Lambda= 0.065845 statistics sampled from 32351 (32631) to 32351 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.71), E-opt: 0.2 (0.383), width: 16 Scan time: 12.880 The best scores are: opt bits E(85289) NP_001123572 (OMIM: 604535) kinesin-like protein K ( 826) 5371 525.3 4.2e-148 NP_001305639 (OMIM: 604535) kinesin-like protein K ( 848) 5371 525.4 4.3e-148 XP_011521378 (OMIM: 604535) PREDICTED: kinesin-lik ( 875) 5371 525.4 4.3e-148 NP_005541 (OMIM: 604535) kinesin-like protein KIFC ( 833) 5366 524.9 5.8e-148 XP_016878712 (OMIM: 604535) PREDICTED: kinesin-lik ( 855) 5366 524.9 5.9e-148 XP_011521379 (OMIM: 604535) PREDICTED: kinesin-lik ( 861) 5366 524.9 6e-148 XP_011521377 (OMIM: 604535) PREDICTED: kinesin-lik ( 882) 5366 524.9 6.1e-148 XP_016878713 (OMIM: 604535) PREDICTED: kinesin-lik ( 912) 4629 454.9 7.4e-127 XP_016878711 (OMIM: 604535) PREDICTED: kinesin-lik ( 912) 4629 454.9 7.4e-127 XP_006721251 (OMIM: 604535) PREDICTED: kinesin-lik (1022) 4629 455.0 8e-127 XP_016878709 (OMIM: 604535) PREDICTED: kinesin-lik (1057) 4629 455.0 8.1e-127 XP_016878708 (OMIM: 604535) PREDICTED: kinesin-lik (1079) 4629 455.0 8.3e-127 XP_016878716 (OMIM: 604535) PREDICTED: kinesin-lik ( 768) 4623 454.3 9.8e-127 NP_001305640 (OMIM: 604535) kinesin-like protein K ( 768) 4623 454.3 9.8e-127 NP_001305641 (OMIM: 604535) kinesin-like protein K ( 724) 4620 453.9 1.1e-126 XP_016878710 (OMIM: 604535) PREDICTED: kinesin-lik ( 989) 4623 454.4 1.2e-126 XP_005256001 (OMIM: 604535) PREDICTED: kinesin-lik ( 775) 4618 453.8 1.4e-126 XP_016878715 (OMIM: 604535) PREDICTED: kinesin-lik ( 775) 4618 453.8 1.4e-126 XP_005255994 (OMIM: 604535) PREDICTED: kinesin-lik ( 996) 4618 453.9 1.6e-126 XP_016878714 (OMIM: 604535) PREDICTED: kinesin-lik ( 776) 4615 453.5 1.7e-126 NP_001123571 (OMIM: 604535) kinesin-like protein K ( 687) 4406 433.6 1.5e-120 NP_001305644 (OMIM: 604535) kinesin-like protein K ( 687) 4406 433.6 1.5e-120 NP_001305643 (OMIM: 604535) kinesin-like protein K ( 687) 4406 433.6 1.5e-120 XP_011521380 (OMIM: 604535) PREDICTED: kinesin-lik ( 694) 4401 433.1 2e-120 XP_011521381 (OMIM: 604535) PREDICTED: kinesin-lik ( 694) 4401 433.1 2e-120 NP_001305642 (OMIM: 604535) kinesin-like protein K ( 684) 4370 430.2 1.6e-119 XP_016864485 (OMIM: 604683) PREDICTED: kinesin-lik ( 697) 845 95.3 9.9e-19 NP_008985 (OMIM: 604683) kinesin-like protein KIF3 ( 699) 845 95.3 9.9e-19 XP_016864484 (OMIM: 604683) PREDICTED: kinesin-lik ( 700) 845 95.3 1e-18 NP_001287721 (OMIM: 604683) kinesin-like protein K ( 702) 845 95.3 1e-18 XP_006714589 (OMIM: 604683) PREDICTED: kinesin-lik ( 724) 845 95.3 1e-18 NP_001287720 (OMIM: 604683) kinesin-like protein K ( 726) 845 95.3 1e-18 NP_004789 (OMIM: 603754) kinesin-like protein KIF3 ( 747) 817 92.7 6.6e-18 XP_005246008 (OMIM: 605037) PREDICTED: kinesin-lik ( 984) 758 87.2 3.8e-16 XP_005246007 (OMIM: 605037) PREDICTED: kinesin-lik ( 985) 758 87.2 3.8e-16 XP_011540147 (OMIM: 605037) PREDICTED: kinesin-lik ( 992) 758 87.2 3.9e-16 XP_011540146 (OMIM: 605037) PREDICTED: kinesin-lik ( 997) 758 87.2 3.9e-16 XP_011540145 (OMIM: 605037) PREDICTED: kinesin-lik (1017) 758 87.2 3.9e-16 NP_001116291 (OMIM: 605037) kinesin-like protein K (1028) 758 87.2 4e-16 NP_065867 (OMIM: 605037) kinesin-like protein KIF1 (1029) 758 87.2 4e-16 XP_011540144 (OMIM: 605037) PREDICTED: kinesin-lik (1031) 758 87.2 4e-16 XP_011540143 (OMIM: 605037) PREDICTED: kinesin-lik (1038) 758 87.2 4e-16 XP_011540142 (OMIM: 605037) PREDICTED: kinesin-lik (1042) 758 87.2 4e-16 XP_011540141 (OMIM: 605037) PREDICTED: kinesin-lik (1043) 758 87.2 4e-16 XP_011540140 (OMIM: 605037) PREDICTED: kinesin-lik (1062) 758 87.3 4e-16 XP_011540139 (OMIM: 605037) PREDICTED: kinesin-lik (1063) 758 87.3 4e-16 NP_004512 (OMIM: 602809) kinesin-1 heavy chain [Ho ( 963) 743 85.8 1e-15 NP_004975 (OMIM: 602821,604187) kinesin heavy chai (1032) 724 84.0 3.7e-15 XP_016859551 (OMIM: 604593,615282) PREDICTED: kine ( 957) 719 83.5 4.9e-15 NP_004513 (OMIM: 604593,615282) kinesin heavy chai ( 957) 719 83.5 4.9e-15 >>NP_001123572 (OMIM: 604535) kinesin-like protein KIFC3 (826 aa) initn: 5371 init1: 5371 opt: 5371 Z-score: 2779.9 bits: 525.3 E(85289): 4.2e-148 Smith-Waterman score: 5371; 100.0% identity (100.0% similar) in 826 aa overlap (1-826:1-826) 10 20 30 40 50 60 pF1KB4 MVPSRRTWNLGATPSLRGLWRVGRAPEPEPGMARPAPAPASPAARPFPHTGPGRLRTGRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MVPSRRTWNLGATPSLRGLWRVGRAPEPEPGMARPAPAPASPAARPFPHTGPGRLRTGRG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 KDTPVCGDEDSSARSAARPALAQCRALSVDWAGPGSPHGLYLTLQVEHLKEKLISQAQEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KDTPVCGDEDSSARSAARPALAQCRALSVDWAGPGSPHGLYLTLQVEHLKEKLISQAQEV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 SRLRSELGGTDLEKHRDLLMVENERLRQEMRRCEAELQELRTKPAGPCPGCEHSQESAQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SRLRSELGGTDLEKHRDLLMVENERLRQEMRRCEAELQELRTKPAGPCPGCEHSQESAQL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 RDKLSQLQLEMAESKGMLSELNLEVQQKTDRLAEVELRLKDCLAEKAQEEERLSRRLRDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RDKLSQLQLEMAESKGMLSELNLEVQQKTDRLAEVELRLKDCLAEKAQEEERLSRRLRDS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 HETIASLRAQSPPVKYVIKTVEVESSKTKQALSESQARNQHLQEQVAMQRQVLKEMEQQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HETIASLRAQSPPVKYVIKTVEVESSKTKQALSESQARNQHLQEQVAMQRQVLKEMEQQL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 QSSHQLTARLRAQIAMYESELERAHGQMLEEMQSLEEDKNRAIEEAFARAQVEMKAVHEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QSSHQLTARLRAQIAMYESELERAHGQMLEEMQSLEEDKNRAIEEAFARAQVEMKAVHEN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 LAGVRTNLLTLQPALRTLTNDYNGLKRQVRGFPLLLQEALRSVKAEIGQAIEEVNSNNQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LAGVRTNLLTLQPALRTLTNDYNGLKRQVRGFPLLLQEALRSVKAEIGQAIEEVNSNNQE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB4 LLRKYRRELQLRKKCHNELVRLKGNIRVIARVRPVTKEDGEGPEATNAVTFDADDDSIIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLRKYRRELQLRKKCHNELVRLKGNIRVIARVRPVTKEDGEGPEATNAVTFDADDDSIIH 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB4 LLHKGKPVSFELDKVFSPQASQQDVFQEVQALVTSCIDGFNVCIFAYGQTGAGKTYTMEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLHKGKPVSFELDKVFSPQASQQDVFQEVQALVTSCIDGFNVCIFAYGQTGAGKTYTMEG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB4 TAENPGINQRALQLLFSEVQEKASDWEYTITVSAAEIYNEVLRDLLGKEPQEKLEIRLCP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TAENPGINQRALQLLFSEVQEKASDWEYTITVSAAEIYNEVLRDLLGKEPQEKLEIRLCP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB4 DGSGQLYVPGLTEFQVQSVDDINKVFEFGHTNRTTEFTNLNEHSSRSHALLIVTVRGVDC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DGSGQLYVPGLTEFQVQSVDDINKVFEFGHTNRTTEFTNLNEHSSRSHALLIVTVRGVDC 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB4 STGLRTTGKLNLVDLAGSERVGKSGAEGSRLREAQHINKSLSALGDVIAALRSRQGHVPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 STGLRTTGKLNLVDLAGSERVGKSGAEGSRLREAQHINKSLSALGDVIAALRSRQGHVPF 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB4 RNSKLTYLLQDSLSGDSKTLMVVQVSPVEKNTSETLYSLKFAERVRSVELGPGLRRAELG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RNSKLTYLLQDSLSGDSKTLMVVQVSPVEKNTSETLYSLKFAERVRSVELGPGLRRAELG 730 740 750 760 770 780 790 800 810 820 pF1KB4 SWSSQEHLEWEPACQTPQPSARAHSAPSSGTSSRPGSIRRKLQPSA :::::::::::::::::::::::::::::::::::::::::::::: NP_001 SWSSQEHLEWEPACQTPQPSARAHSAPSSGTSSRPGSIRRKLQPSA 790 800 810 820 >>NP_001305639 (OMIM: 604535) kinesin-like protein KIFC3 (848 aa) initn: 5371 init1: 5371 opt: 5371 Z-score: 2779.8 bits: 525.4 E(85289): 4.3e-148 Smith-Waterman score: 5371; 100.0% identity (100.0% similar) in 826 aa overlap (1-826:23-848) 10 20 30 pF1KB4 MVPSRRTWNLGATPSLRGLWRVGRAPEPEPGMARPAPA :::::::::::::::::::::::::::::::::::::: NP_001 MCASACKDTAAWCPEEAAEPQAMVPSRRTWNLGATPSLRGLWRVGRAPEPEPGMARPAPA 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB4 PASPAARPFPHTGPGRLRTGRGKDTPVCGDEDSSARSAARPALAQCRALSVDWAGPGSPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PASPAARPFPHTGPGRLRTGRGKDTPVCGDEDSSARSAARPALAQCRALSVDWAGPGSPH 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB4 GLYLTLQVEHLKEKLISQAQEVSRLRSELGGTDLEKHRDLLMVENERLRQEMRRCEAELQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GLYLTLQVEHLKEKLISQAQEVSRLRSELGGTDLEKHRDLLMVENERLRQEMRRCEAELQ 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB4 ELRTKPAGPCPGCEHSQESAQLRDKLSQLQLEMAESKGMLSELNLEVQQKTDRLAEVELR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ELRTKPAGPCPGCEHSQESAQLRDKLSQLQLEMAESKGMLSELNLEVQQKTDRLAEVELR 190 200 210 220 230 240 220 230 240 250 260 270 pF1KB4 LKDCLAEKAQEEERLSRRLRDSHETIASLRAQSPPVKYVIKTVEVESSKTKQALSESQAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LKDCLAEKAQEEERLSRRLRDSHETIASLRAQSPPVKYVIKTVEVESSKTKQALSESQAR 250 260 270 280 290 300 280 290 300 310 320 330 pF1KB4 NQHLQEQVAMQRQVLKEMEQQLQSSHQLTARLRAQIAMYESELERAHGQMLEEMQSLEED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NQHLQEQVAMQRQVLKEMEQQLQSSHQLTARLRAQIAMYESELERAHGQMLEEMQSLEED 310 320 330 340 350 360 340 350 360 370 380 390 pF1KB4 KNRAIEEAFARAQVEMKAVHENLAGVRTNLLTLQPALRTLTNDYNGLKRQVRGFPLLLQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KNRAIEEAFARAQVEMKAVHENLAGVRTNLLTLQPALRTLTNDYNGLKRQVRGFPLLLQE 370 380 390 400 410 420 400 410 420 430 440 450 pF1KB4 ALRSVKAEIGQAIEEVNSNNQELLRKYRRELQLRKKCHNELVRLKGNIRVIARVRPVTKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ALRSVKAEIGQAIEEVNSNNQELLRKYRRELQLRKKCHNELVRLKGNIRVIARVRPVTKE 430 440 450 460 470 480 460 470 480 490 500 510 pF1KB4 DGEGPEATNAVTFDADDDSIIHLLHKGKPVSFELDKVFSPQASQQDVFQEVQALVTSCID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DGEGPEATNAVTFDADDDSIIHLLHKGKPVSFELDKVFSPQASQQDVFQEVQALVTSCID 490 500 510 520 530 540 520 530 540 550 560 570 pF1KB4 GFNVCIFAYGQTGAGKTYTMEGTAENPGINQRALQLLFSEVQEKASDWEYTITVSAAEIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GFNVCIFAYGQTGAGKTYTMEGTAENPGINQRALQLLFSEVQEKASDWEYTITVSAAEIY 550 560 570 580 590 600 580 590 600 610 620 630 pF1KB4 NEVLRDLLGKEPQEKLEIRLCPDGSGQLYVPGLTEFQVQSVDDINKVFEFGHTNRTTEFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NEVLRDLLGKEPQEKLEIRLCPDGSGQLYVPGLTEFQVQSVDDINKVFEFGHTNRTTEFT 610 620 630 640 650 660 640 650 660 670 680 690 pF1KB4 NLNEHSSRSHALLIVTVRGVDCSTGLRTTGKLNLVDLAGSERVGKSGAEGSRLREAQHIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NLNEHSSRSHALLIVTVRGVDCSTGLRTTGKLNLVDLAGSERVGKSGAEGSRLREAQHIN 670 680 690 700 710 720 700 710 720 730 740 750 pF1KB4 KSLSALGDVIAALRSRQGHVPFRNSKLTYLLQDSLSGDSKTLMVVQVSPVEKNTSETLYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KSLSALGDVIAALRSRQGHVPFRNSKLTYLLQDSLSGDSKTLMVVQVSPVEKNTSETLYS 730 740 750 760 770 780 760 770 780 790 800 810 pF1KB4 LKFAERVRSVELGPGLRRAELGSWSSQEHLEWEPACQTPQPSARAHSAPSSGTSSRPGSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LKFAERVRSVELGPGLRRAELGSWSSQEHLEWEPACQTPQPSARAHSAPSSGTSSRPGSI 790 800 810 820 830 840 820 pF1KB4 RRKLQPSA :::::::: NP_001 RRKLQPSA >>XP_011521378 (OMIM: 604535) PREDICTED: kinesin-like pr (875 aa) initn: 5371 init1: 5371 opt: 5371 Z-score: 2779.6 bits: 525.4 E(85289): 4.3e-148 Smith-Waterman score: 5371; 100.0% identity (100.0% similar) in 826 aa overlap (1-826:50-875) 10 20 30 pF1KB4 MVPSRRTWNLGATPSLRGLWRVGRAPEPEP :::::::::::::::::::::::::::::: XP_011 RHQETLRLEAGVPEQCKAAWCPEEAAEPQAMVPSRRTWNLGATPSLRGLWRVGRAPEPEP 20 30 40 50 60 70 40 50 60 70 80 90 pF1KB4 GMARPAPAPASPAARPFPHTGPGRLRTGRGKDTPVCGDEDSSARSAARPALAQCRALSVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GMARPAPAPASPAARPFPHTGPGRLRTGRGKDTPVCGDEDSSARSAARPALAQCRALSVD 80 90 100 110 120 130 100 110 120 130 140 150 pF1KB4 WAGPGSPHGLYLTLQVEHLKEKLISQAQEVSRLRSELGGTDLEKHRDLLMVENERLRQEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WAGPGSPHGLYLTLQVEHLKEKLISQAQEVSRLRSELGGTDLEKHRDLLMVENERLRQEM 140 150 160 170 180 190 160 170 180 190 200 210 pF1KB4 RRCEAELQELRTKPAGPCPGCEHSQESAQLRDKLSQLQLEMAESKGMLSELNLEVQQKTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RRCEAELQELRTKPAGPCPGCEHSQESAQLRDKLSQLQLEMAESKGMLSELNLEVQQKTD 200 210 220 230 240 250 220 230 240 250 260 270 pF1KB4 RLAEVELRLKDCLAEKAQEEERLSRRLRDSHETIASLRAQSPPVKYVIKTVEVESSKTKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RLAEVELRLKDCLAEKAQEEERLSRRLRDSHETIASLRAQSPPVKYVIKTVEVESSKTKQ 260 270 280 290 300 310 280 290 300 310 320 330 pF1KB4 ALSESQARNQHLQEQVAMQRQVLKEMEQQLQSSHQLTARLRAQIAMYESELERAHGQMLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ALSESQARNQHLQEQVAMQRQVLKEMEQQLQSSHQLTARLRAQIAMYESELERAHGQMLE 320 330 340 350 360 370 340 350 360 370 380 390 pF1KB4 EMQSLEEDKNRAIEEAFARAQVEMKAVHENLAGVRTNLLTLQPALRTLTNDYNGLKRQVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EMQSLEEDKNRAIEEAFARAQVEMKAVHENLAGVRTNLLTLQPALRTLTNDYNGLKRQVR 380 390 400 410 420 430 400 410 420 430 440 450 pF1KB4 GFPLLLQEALRSVKAEIGQAIEEVNSNNQELLRKYRRELQLRKKCHNELVRLKGNIRVIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GFPLLLQEALRSVKAEIGQAIEEVNSNNQELLRKYRRELQLRKKCHNELVRLKGNIRVIA 440 450 460 470 480 490 460 470 480 490 500 510 pF1KB4 RVRPVTKEDGEGPEATNAVTFDADDDSIIHLLHKGKPVSFELDKVFSPQASQQDVFQEVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RVRPVTKEDGEGPEATNAVTFDADDDSIIHLLHKGKPVSFELDKVFSPQASQQDVFQEVQ 500 510 520 530 540 550 520 530 540 550 560 570 pF1KB4 ALVTSCIDGFNVCIFAYGQTGAGKTYTMEGTAENPGINQRALQLLFSEVQEKASDWEYTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ALVTSCIDGFNVCIFAYGQTGAGKTYTMEGTAENPGINQRALQLLFSEVQEKASDWEYTI 560 570 580 590 600 610 580 590 600 610 620 630 pF1KB4 TVSAAEIYNEVLRDLLGKEPQEKLEIRLCPDGSGQLYVPGLTEFQVQSVDDINKVFEFGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TVSAAEIYNEVLRDLLGKEPQEKLEIRLCPDGSGQLYVPGLTEFQVQSVDDINKVFEFGH 620 630 640 650 660 670 640 650 660 670 680 690 pF1KB4 TNRTTEFTNLNEHSSRSHALLIVTVRGVDCSTGLRTTGKLNLVDLAGSERVGKSGAEGSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TNRTTEFTNLNEHSSRSHALLIVTVRGVDCSTGLRTTGKLNLVDLAGSERVGKSGAEGSR 680 690 700 710 720 730 700 710 720 730 740 750 pF1KB4 LREAQHINKSLSALGDVIAALRSRQGHVPFRNSKLTYLLQDSLSGDSKTLMVVQVSPVEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LREAQHINKSLSALGDVIAALRSRQGHVPFRNSKLTYLLQDSLSGDSKTLMVVQVSPVEK 740 750 760 770 780 790 760 770 780 790 800 810 pF1KB4 NTSETLYSLKFAERVRSVELGPGLRRAELGSWSSQEHLEWEPACQTPQPSARAHSAPSSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NTSETLYSLKFAERVRSVELGPGLRRAELGSWSSQEHLEWEPACQTPQPSARAHSAPSSG 800 810 820 830 840 850 820 pF1KB4 TSSRPGSIRRKLQPSA :::::::::::::::: XP_011 TSSRPGSIRRKLQPSA 860 870 >>NP_005541 (OMIM: 604535) kinesin-like protein KIFC3 is (833 aa) initn: 5366 init1: 5366 opt: 5366 Z-score: 2777.3 bits: 524.9 E(85289): 5.8e-148 Smith-Waterman score: 5366; 100.0% identity (100.0% similar) in 825 aa overlap (1-825:1-825) 10 20 30 40 50 60 pF1KB4 MVPSRRTWNLGATPSLRGLWRVGRAPEPEPGMARPAPAPASPAARPFPHTGPGRLRTGRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MVPSRRTWNLGATPSLRGLWRVGRAPEPEPGMARPAPAPASPAARPFPHTGPGRLRTGRG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 KDTPVCGDEDSSARSAARPALAQCRALSVDWAGPGSPHGLYLTLQVEHLKEKLISQAQEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 KDTPVCGDEDSSARSAARPALAQCRALSVDWAGPGSPHGLYLTLQVEHLKEKLISQAQEV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 SRLRSELGGTDLEKHRDLLMVENERLRQEMRRCEAELQELRTKPAGPCPGCEHSQESAQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 SRLRSELGGTDLEKHRDLLMVENERLRQEMRRCEAELQELRTKPAGPCPGCEHSQESAQL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 RDKLSQLQLEMAESKGMLSELNLEVQQKTDRLAEVELRLKDCLAEKAQEEERLSRRLRDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 RDKLSQLQLEMAESKGMLSELNLEVQQKTDRLAEVELRLKDCLAEKAQEEERLSRRLRDS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 HETIASLRAQSPPVKYVIKTVEVESSKTKQALSESQARNQHLQEQVAMQRQVLKEMEQQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 HETIASLRAQSPPVKYVIKTVEVESSKTKQALSESQARNQHLQEQVAMQRQVLKEMEQQL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 QSSHQLTARLRAQIAMYESELERAHGQMLEEMQSLEEDKNRAIEEAFARAQVEMKAVHEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 QSSHQLTARLRAQIAMYESELERAHGQMLEEMQSLEEDKNRAIEEAFARAQVEMKAVHEN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 LAGVRTNLLTLQPALRTLTNDYNGLKRQVRGFPLLLQEALRSVKAEIGQAIEEVNSNNQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 LAGVRTNLLTLQPALRTLTNDYNGLKRQVRGFPLLLQEALRSVKAEIGQAIEEVNSNNQE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB4 LLRKYRRELQLRKKCHNELVRLKGNIRVIARVRPVTKEDGEGPEATNAVTFDADDDSIIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 LLRKYRRELQLRKKCHNELVRLKGNIRVIARVRPVTKEDGEGPEATNAVTFDADDDSIIH 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB4 LLHKGKPVSFELDKVFSPQASQQDVFQEVQALVTSCIDGFNVCIFAYGQTGAGKTYTMEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 LLHKGKPVSFELDKVFSPQASQQDVFQEVQALVTSCIDGFNVCIFAYGQTGAGKTYTMEG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB4 TAENPGINQRALQLLFSEVQEKASDWEYTITVSAAEIYNEVLRDLLGKEPQEKLEIRLCP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 TAENPGINQRALQLLFSEVQEKASDWEYTITVSAAEIYNEVLRDLLGKEPQEKLEIRLCP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB4 DGSGQLYVPGLTEFQVQSVDDINKVFEFGHTNRTTEFTNLNEHSSRSHALLIVTVRGVDC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 DGSGQLYVPGLTEFQVQSVDDINKVFEFGHTNRTTEFTNLNEHSSRSHALLIVTVRGVDC 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB4 STGLRTTGKLNLVDLAGSERVGKSGAEGSRLREAQHINKSLSALGDVIAALRSRQGHVPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 STGLRTTGKLNLVDLAGSERVGKSGAEGSRLREAQHINKSLSALGDVIAALRSRQGHVPF 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB4 RNSKLTYLLQDSLSGDSKTLMVVQVSPVEKNTSETLYSLKFAERVRSVELGPGLRRAELG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 RNSKLTYLLQDSLSGDSKTLMVVQVSPVEKNTSETLYSLKFAERVRSVELGPGLRRAELG 730 740 750 760 770 780 790 800 810 820 pF1KB4 SWSSQEHLEWEPACQTPQPSARAHSAPSSGTSSRPGSIRRKLQPSA ::::::::::::::::::::::::::::::::::::::::::::: NP_005 SWSSQEHLEWEPACQTPQPSARAHSAPSSGTSSRPGSIRRKLQPSGKSRPLPV 790 800 810 820 830 >>XP_016878712 (OMIM: 604535) PREDICTED: kinesin-like pr (855 aa) initn: 5366 init1: 5366 opt: 5366 Z-score: 2777.2 bits: 524.9 E(85289): 5.9e-148 Smith-Waterman score: 5366; 100.0% identity (100.0% similar) in 825 aa overlap (1-825:23-847) 10 20 30 pF1KB4 MVPSRRTWNLGATPSLRGLWRVGRAPEPEPGMARPAPA :::::::::::::::::::::::::::::::::::::: XP_016 MCASACKDTAAWCPEEAAEPQAMVPSRRTWNLGATPSLRGLWRVGRAPEPEPGMARPAPA 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB4 PASPAARPFPHTGPGRLRTGRGKDTPVCGDEDSSARSAARPALAQCRALSVDWAGPGSPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PASPAARPFPHTGPGRLRTGRGKDTPVCGDEDSSARSAARPALAQCRALSVDWAGPGSPH 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB4 GLYLTLQVEHLKEKLISQAQEVSRLRSELGGTDLEKHRDLLMVENERLRQEMRRCEAELQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GLYLTLQVEHLKEKLISQAQEVSRLRSELGGTDLEKHRDLLMVENERLRQEMRRCEAELQ 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB4 ELRTKPAGPCPGCEHSQESAQLRDKLSQLQLEMAESKGMLSELNLEVQQKTDRLAEVELR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELRTKPAGPCPGCEHSQESAQLRDKLSQLQLEMAESKGMLSELNLEVQQKTDRLAEVELR 190 200 210 220 230 240 220 230 240 250 260 270 pF1KB4 LKDCLAEKAQEEERLSRRLRDSHETIASLRAQSPPVKYVIKTVEVESSKTKQALSESQAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LKDCLAEKAQEEERLSRRLRDSHETIASLRAQSPPVKYVIKTVEVESSKTKQALSESQAR 250 260 270 280 290 300 280 290 300 310 320 330 pF1KB4 NQHLQEQVAMQRQVLKEMEQQLQSSHQLTARLRAQIAMYESELERAHGQMLEEMQSLEED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NQHLQEQVAMQRQVLKEMEQQLQSSHQLTARLRAQIAMYESELERAHGQMLEEMQSLEED 310 320 330 340 350 360 340 350 360 370 380 390 pF1KB4 KNRAIEEAFARAQVEMKAVHENLAGVRTNLLTLQPALRTLTNDYNGLKRQVRGFPLLLQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KNRAIEEAFARAQVEMKAVHENLAGVRTNLLTLQPALRTLTNDYNGLKRQVRGFPLLLQE 370 380 390 400 410 420 400 410 420 430 440 450 pF1KB4 ALRSVKAEIGQAIEEVNSNNQELLRKYRRELQLRKKCHNELVRLKGNIRVIARVRPVTKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALRSVKAEIGQAIEEVNSNNQELLRKYRRELQLRKKCHNELVRLKGNIRVIARVRPVTKE 430 440 450 460 470 480 460 470 480 490 500 510 pF1KB4 DGEGPEATNAVTFDADDDSIIHLLHKGKPVSFELDKVFSPQASQQDVFQEVQALVTSCID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DGEGPEATNAVTFDADDDSIIHLLHKGKPVSFELDKVFSPQASQQDVFQEVQALVTSCID 490 500 510 520 530 540 520 530 540 550 560 570 pF1KB4 GFNVCIFAYGQTGAGKTYTMEGTAENPGINQRALQLLFSEVQEKASDWEYTITVSAAEIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GFNVCIFAYGQTGAGKTYTMEGTAENPGINQRALQLLFSEVQEKASDWEYTITVSAAEIY 550 560 570 580 590 600 580 590 600 610 620 630 pF1KB4 NEVLRDLLGKEPQEKLEIRLCPDGSGQLYVPGLTEFQVQSVDDINKVFEFGHTNRTTEFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NEVLRDLLGKEPQEKLEIRLCPDGSGQLYVPGLTEFQVQSVDDINKVFEFGHTNRTTEFT 610 620 630 640 650 660 640 650 660 670 680 690 pF1KB4 NLNEHSSRSHALLIVTVRGVDCSTGLRTTGKLNLVDLAGSERVGKSGAEGSRLREAQHIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NLNEHSSRSHALLIVTVRGVDCSTGLRTTGKLNLVDLAGSERVGKSGAEGSRLREAQHIN 670 680 690 700 710 720 700 710 720 730 740 750 pF1KB4 KSLSALGDVIAALRSRQGHVPFRNSKLTYLLQDSLSGDSKTLMVVQVSPVEKNTSETLYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KSLSALGDVIAALRSRQGHVPFRNSKLTYLLQDSLSGDSKTLMVVQVSPVEKNTSETLYS 730 740 750 760 770 780 760 770 780 790 800 810 pF1KB4 LKFAERVRSVELGPGLRRAELGSWSSQEHLEWEPACQTPQPSARAHSAPSSGTSSRPGSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LKFAERVRSVELGPGLRRAELGSWSSQEHLEWEPACQTPQPSARAHSAPSSGTSSRPGSI 790 800 810 820 830 840 820 pF1KB4 RRKLQPSA ::::::: XP_016 RRKLQPSGKSRPLPV 850 >>XP_011521379 (OMIM: 604535) PREDICTED: kinesin-like pr (861 aa) initn: 5366 init1: 5366 opt: 5366 Z-score: 2777.2 bits: 524.9 E(85289): 6e-148 Smith-Waterman score: 5366; 100.0% identity (100.0% similar) in 825 aa overlap (1-825:29-853) 10 20 30 pF1KB4 MVPSRRTWNLGATPSLRGLWRVGRAPEPEPGM :::::::::::::::::::::::::::::::: XP_011 MLPLFGRQRTEWLLQAAWCPEEAAEPQAMVPSRRTWNLGATPSLRGLWRVGRAPEPEPGM 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB4 ARPAPAPASPAARPFPHTGPGRLRTGRGKDTPVCGDEDSSARSAARPALAQCRALSVDWA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ARPAPAPASPAARPFPHTGPGRLRTGRGKDTPVCGDEDSSARSAARPALAQCRALSVDWA 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB4 GPGSPHGLYLTLQVEHLKEKLISQAQEVSRLRSELGGTDLEKHRDLLMVENERLRQEMRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GPGSPHGLYLTLQVEHLKEKLISQAQEVSRLRSELGGTDLEKHRDLLMVENERLRQEMRR 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB4 CEAELQELRTKPAGPCPGCEHSQESAQLRDKLSQLQLEMAESKGMLSELNLEVQQKTDRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CEAELQELRTKPAGPCPGCEHSQESAQLRDKLSQLQLEMAESKGMLSELNLEVQQKTDRL 190 200 210 220 230 240 220 230 240 250 260 270 pF1KB4 AEVELRLKDCLAEKAQEEERLSRRLRDSHETIASLRAQSPPVKYVIKTVEVESSKTKQAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AEVELRLKDCLAEKAQEEERLSRRLRDSHETIASLRAQSPPVKYVIKTVEVESSKTKQAL 250 260 270 280 290 300 280 290 300 310 320 330 pF1KB4 SESQARNQHLQEQVAMQRQVLKEMEQQLQSSHQLTARLRAQIAMYESELERAHGQMLEEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SESQARNQHLQEQVAMQRQVLKEMEQQLQSSHQLTARLRAQIAMYESELERAHGQMLEEM 310 320 330 340 350 360 340 350 360 370 380 390 pF1KB4 QSLEEDKNRAIEEAFARAQVEMKAVHENLAGVRTNLLTLQPALRTLTNDYNGLKRQVRGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QSLEEDKNRAIEEAFARAQVEMKAVHENLAGVRTNLLTLQPALRTLTNDYNGLKRQVRGF 370 380 390 400 410 420 400 410 420 430 440 450 pF1KB4 PLLLQEALRSVKAEIGQAIEEVNSNNQELLRKYRRELQLRKKCHNELVRLKGNIRVIARV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PLLLQEALRSVKAEIGQAIEEVNSNNQELLRKYRRELQLRKKCHNELVRLKGNIRVIARV 430 440 450 460 470 480 460 470 480 490 500 510 pF1KB4 RPVTKEDGEGPEATNAVTFDADDDSIIHLLHKGKPVSFELDKVFSPQASQQDVFQEVQAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RPVTKEDGEGPEATNAVTFDADDDSIIHLLHKGKPVSFELDKVFSPQASQQDVFQEVQAL 490 500 510 520 530 540 520 530 540 550 560 570 pF1KB4 VTSCIDGFNVCIFAYGQTGAGKTYTMEGTAENPGINQRALQLLFSEVQEKASDWEYTITV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VTSCIDGFNVCIFAYGQTGAGKTYTMEGTAENPGINQRALQLLFSEVQEKASDWEYTITV 550 560 570 580 590 600 580 590 600 610 620 630 pF1KB4 SAAEIYNEVLRDLLGKEPQEKLEIRLCPDGSGQLYVPGLTEFQVQSVDDINKVFEFGHTN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SAAEIYNEVLRDLLGKEPQEKLEIRLCPDGSGQLYVPGLTEFQVQSVDDINKVFEFGHTN 610 620 630 640 650 660 640 650 660 670 680 690 pF1KB4 RTTEFTNLNEHSSRSHALLIVTVRGVDCSTGLRTTGKLNLVDLAGSERVGKSGAEGSRLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RTTEFTNLNEHSSRSHALLIVTVRGVDCSTGLRTTGKLNLVDLAGSERVGKSGAEGSRLR 670 680 690 700 710 720 700 710 720 730 740 750 pF1KB4 EAQHINKSLSALGDVIAALRSRQGHVPFRNSKLTYLLQDSLSGDSKTLMVVQVSPVEKNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EAQHINKSLSALGDVIAALRSRQGHVPFRNSKLTYLLQDSLSGDSKTLMVVQVSPVEKNT 730 740 750 760 770 780 760 770 780 790 800 810 pF1KB4 SETLYSLKFAERVRSVELGPGLRRAELGSWSSQEHLEWEPACQTPQPSARAHSAPSSGTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SETLYSLKFAERVRSVELGPGLRRAELGSWSSQEHLEWEPACQTPQPSARAHSAPSSGTS 790 800 810 820 830 840 820 pF1KB4 SRPGSIRRKLQPSA ::::::::::::: XP_011 SRPGSIRRKLQPSGKSRPLPV 850 860 >>XP_011521377 (OMIM: 604535) PREDICTED: kinesin-like pr (882 aa) initn: 5366 init1: 5366 opt: 5366 Z-score: 2777.0 bits: 524.9 E(85289): 6.1e-148 Smith-Waterman score: 5366; 100.0% identity (100.0% similar) in 825 aa overlap (1-825:50-874) 10 20 30 pF1KB4 MVPSRRTWNLGATPSLRGLWRVGRAPEPEP :::::::::::::::::::::::::::::: XP_011 RHQETLRLEAGVPEQCKAAWCPEEAAEPQAMVPSRRTWNLGATPSLRGLWRVGRAPEPEP 20 30 40 50 60 70 40 50 60 70 80 90 pF1KB4 GMARPAPAPASPAARPFPHTGPGRLRTGRGKDTPVCGDEDSSARSAARPALAQCRALSVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GMARPAPAPASPAARPFPHTGPGRLRTGRGKDTPVCGDEDSSARSAARPALAQCRALSVD 80 90 100 110 120 130 100 110 120 130 140 150 pF1KB4 WAGPGSPHGLYLTLQVEHLKEKLISQAQEVSRLRSELGGTDLEKHRDLLMVENERLRQEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WAGPGSPHGLYLTLQVEHLKEKLISQAQEVSRLRSELGGTDLEKHRDLLMVENERLRQEM 140 150 160 170 180 190 160 170 180 190 200 210 pF1KB4 RRCEAELQELRTKPAGPCPGCEHSQESAQLRDKLSQLQLEMAESKGMLSELNLEVQQKTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RRCEAELQELRTKPAGPCPGCEHSQESAQLRDKLSQLQLEMAESKGMLSELNLEVQQKTD 200 210 220 230 240 250 220 230 240 250 260 270 pF1KB4 RLAEVELRLKDCLAEKAQEEERLSRRLRDSHETIASLRAQSPPVKYVIKTVEVESSKTKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RLAEVELRLKDCLAEKAQEEERLSRRLRDSHETIASLRAQSPPVKYVIKTVEVESSKTKQ 260 270 280 290 300 310 280 290 300 310 320 330 pF1KB4 ALSESQARNQHLQEQVAMQRQVLKEMEQQLQSSHQLTARLRAQIAMYESELERAHGQMLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ALSESQARNQHLQEQVAMQRQVLKEMEQQLQSSHQLTARLRAQIAMYESELERAHGQMLE 320 330 340 350 360 370 340 350 360 370 380 390 pF1KB4 EMQSLEEDKNRAIEEAFARAQVEMKAVHENLAGVRTNLLTLQPALRTLTNDYNGLKRQVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EMQSLEEDKNRAIEEAFARAQVEMKAVHENLAGVRTNLLTLQPALRTLTNDYNGLKRQVR 380 390 400 410 420 430 400 410 420 430 440 450 pF1KB4 GFPLLLQEALRSVKAEIGQAIEEVNSNNQELLRKYRRELQLRKKCHNELVRLKGNIRVIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GFPLLLQEALRSVKAEIGQAIEEVNSNNQELLRKYRRELQLRKKCHNELVRLKGNIRVIA 440 450 460 470 480 490 460 470 480 490 500 510 pF1KB4 RVRPVTKEDGEGPEATNAVTFDADDDSIIHLLHKGKPVSFELDKVFSPQASQQDVFQEVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RVRPVTKEDGEGPEATNAVTFDADDDSIIHLLHKGKPVSFELDKVFSPQASQQDVFQEVQ 500 510 520 530 540 550 520 530 540 550 560 570 pF1KB4 ALVTSCIDGFNVCIFAYGQTGAGKTYTMEGTAENPGINQRALQLLFSEVQEKASDWEYTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ALVTSCIDGFNVCIFAYGQTGAGKTYTMEGTAENPGINQRALQLLFSEVQEKASDWEYTI 560 570 580 590 600 610 580 590 600 610 620 630 pF1KB4 TVSAAEIYNEVLRDLLGKEPQEKLEIRLCPDGSGQLYVPGLTEFQVQSVDDINKVFEFGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TVSAAEIYNEVLRDLLGKEPQEKLEIRLCPDGSGQLYVPGLTEFQVQSVDDINKVFEFGH 620 630 640 650 660 670 640 650 660 670 680 690 pF1KB4 TNRTTEFTNLNEHSSRSHALLIVTVRGVDCSTGLRTTGKLNLVDLAGSERVGKSGAEGSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TNRTTEFTNLNEHSSRSHALLIVTVRGVDCSTGLRTTGKLNLVDLAGSERVGKSGAEGSR 680 690 700 710 720 730 700 710 720 730 740 750 pF1KB4 LREAQHINKSLSALGDVIAALRSRQGHVPFRNSKLTYLLQDSLSGDSKTLMVVQVSPVEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LREAQHINKSLSALGDVIAALRSRQGHVPFRNSKLTYLLQDSLSGDSKTLMVVQVSPVEK 740 750 760 770 780 790 760 770 780 790 800 810 pF1KB4 NTSETLYSLKFAERVRSVELGPGLRRAELGSWSSQEHLEWEPACQTPQPSARAHSAPSSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NTSETLYSLKFAERVRSVELGPGLRRAELGSWSSQEHLEWEPACQTPQPSARAHSAPSSG 800 810 820 830 840 850 820 pF1KB4 TSSRPGSIRRKLQPSA ::::::::::::::: XP_011 TSSRPGSIRRKLQPSGKSRPLPV 860 870 880 >>XP_016878713 (OMIM: 604535) PREDICTED: kinesin-like pr (912 aa) initn: 4621 init1: 4621 opt: 4629 Z-score: 2398.5 bits: 454.9 E(85289): 7.4e-127 Smith-Waterman score: 4655; 91.2% identity (93.8% similar) in 816 aa overlap (10-825:100-904) 10 20 30 pF1KB4 MVPSRRTWNLGATPSLRGLWRVGRAPEPEPGMARPAPAP ::. .. : : : : : : :: XP_016 QLQNQLAEASHPGPPCAPSPCGYQGPGPSPLGGDVDVSGAGRCGVLPTLSPPHLRRCPAL 70 80 90 100 110 120 40 50 60 70 80 90 pF1KB4 ASPAARPFPHTGPGRLRTGRGKDTPVCGDEDSSARSAARPALAQCRALSVDWAGPGSPHG .: ... : :: .:. :. : : . : .:. : . ... .: . : XP_016 GSLSGQNSSDGHP----TGDWHDVS-CS-FDFSLKVDA--SLSACWGRDLSTSGSQGEPG 130 140 150 160 170 180 100 110 120 130 140 150 pF1KB4 LYLTLQVEHLKEKLISQAQEVSRLRSELGGTDLEKHRDLLMVENERLRQEMRRCEAELQE . .::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 F---MQVEHLKEKLISQAQEVSRLRSELGGTDLEKHRDLLMVENERLRQEMRRCEAELQE 190 200 210 220 230 160 170 180 190 200 210 pF1KB4 LRTKPAGPCPGCEHSQESAQLRDKLSQLQLEMAESKGMLSELNLEVQQKTDRLAEVELRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LRTKPAGPCPGCEHSQESAQLRDKLSQLQLEMAESKGMLSELNLEVQQKTDRLAEVELRL 240 250 260 270 280 290 220 230 240 250 260 270 pF1KB4 KDCLAEKAQEEERLSRRLRDSHETIASLRAQSPPVKYVIKTVEVESSKTKQALSESQARN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KDCLAEKAQEEERLSRRLRDSHETIASLRAQSPPVKYVIKTVEVESSKTKQALSESQARN 300 310 320 330 340 350 280 290 300 310 320 330 pF1KB4 QHLQEQVAMQRQVLKEMEQQLQSSHQLTARLRAQIAMYESELERAHGQMLEEMQSLEEDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QHLQEQVAMQRQVLKEMEQQLQSSHQLTARLRAQIAMYESELERAHGQMLEEMQSLEEDK 360 370 380 390 400 410 340 350 360 370 380 390 pF1KB4 NRAIEEAFARAQVEMKAVHENLAGVRTNLLTLQPALRTLTNDYNGLKRQVRGFPLLLQEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NRAIEEAFARAQVEMKAVHENLAGVRTNLLTLQPALRTLTNDYNGLKRQVRGFPLLLQEA 420 430 440 450 460 470 400 410 420 430 440 450 pF1KB4 LRSVKAEIGQAIEEVNSNNQELLRKYRRELQLRKKCHNELVRLKGNIRVIARVRPVTKED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LRSVKAEIGQAIEEVNSNNQELLRKYRRELQLRKKCHNELVRLKGNIRVIARVRPVTKED 480 490 500 510 520 530 460 470 480 490 500 510 pF1KB4 GEGPEATNAVTFDADDDSIIHLLHKGKPVSFELDKVFSPQASQQDVFQEVQALVTSCIDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GEGPEATNAVTFDADDDSIIHLLHKGKPVSFELDKVFSPQASQQDVFQEVQALVTSCIDG 540 550 560 570 580 590 520 530 540 550 560 570 pF1KB4 FNVCIFAYGQTGAGKTYTMEGTAENPGINQRALQLLFSEVQEKASDWEYTITVSAAEIYN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FNVCIFAYGQTGAGKTYTMEGTAENPGINQRALQLLFSEVQEKASDWEYTITVSAAEIYN 600 610 620 630 640 650 580 590 600 610 620 630 pF1KB4 EVLRDLLGKEPQEKLEIRLCPDGSGQLYVPGLTEFQVQSVDDINKVFEFGHTNRTTEFTN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EVLRDLLGKEPQEKLEIRLCPDGSGQLYVPGLTEFQVQSVDDINKVFEFGHTNRTTEFTN 660 670 680 690 700 710 640 650 660 670 680 690 pF1KB4 LNEHSSRSHALLIVTVRGVDCSTGLRTTGKLNLVDLAGSERVGKSGAEGSRLREAQHINK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LNEHSSRSHALLIVTVRGVDCSTGLRTTGKLNLVDLAGSERVGKSGAEGSRLREAQHINK 720 730 740 750 760 770 700 710 720 730 740 750 pF1KB4 SLSALGDVIAALRSRQGHVPFRNSKLTYLLQDSLSGDSKTLMVVQVSPVEKNTSETLYSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SLSALGDVIAALRSRQGHVPFRNSKLTYLLQDSLSGDSKTLMVVQVSPVEKNTSETLYSL 780 790 800 810 820 830 760 770 780 790 800 810 pF1KB4 KFAERVRSVELGPGLRRAELGSWSSQEHLEWEPACQTPQPSARAHSAPSSGTSSRPGSIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KFAERVRSVELGPGLRRAELGSWSSQEHLEWEPACQTPQPSARAHSAPSSGTSSRPGSIR 840 850 860 870 880 890 820 pF1KB4 RKLQPSA :::::: XP_016 RKLQPSGKSRPLPV 900 910 >>XP_016878711 (OMIM: 604535) PREDICTED: kinesin-like pr (912 aa) initn: 4621 init1: 4621 opt: 4629 Z-score: 2398.5 bits: 454.9 E(85289): 7.4e-127 Smith-Waterman score: 4655; 91.2% identity (93.8% similar) in 816 aa overlap (10-825:100-904) 10 20 30 pF1KB4 MVPSRRTWNLGATPSLRGLWRVGRAPEPEPGMARPAPAP ::. .. : : : : : : :: XP_016 QLQNQLAEASHPGPPCAPSPCGYQGPGPSPLGGDVDVSGAGRCGVLPTLSPPHLRRCPAL 70 80 90 100 110 120 40 50 60 70 80 90 pF1KB4 ASPAARPFPHTGPGRLRTGRGKDTPVCGDEDSSARSAARPALAQCRALSVDWAGPGSPHG .: ... : :: .:. :. : : . : .:. : . ... .: . : XP_016 GSLSGQNSSDGHP----TGDWHDVS-CS-FDFSLKVDA--SLSACWGRDLSTSGSQGEPG 130 140 150 160 170 180 100 110 120 130 140 150 pF1KB4 LYLTLQVEHLKEKLISQAQEVSRLRSELGGTDLEKHRDLLMVENERLRQEMRRCEAELQE . .::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 F---MQVEHLKEKLISQAQEVSRLRSELGGTDLEKHRDLLMVENERLRQEMRRCEAELQE 190 200 210 220 230 160 170 180 190 200 210 pF1KB4 LRTKPAGPCPGCEHSQESAQLRDKLSQLQLEMAESKGMLSELNLEVQQKTDRLAEVELRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LRTKPAGPCPGCEHSQESAQLRDKLSQLQLEMAESKGMLSELNLEVQQKTDRLAEVELRL 240 250 260 270 280 290 220 230 240 250 260 270 pF1KB4 KDCLAEKAQEEERLSRRLRDSHETIASLRAQSPPVKYVIKTVEVESSKTKQALSESQARN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KDCLAEKAQEEERLSRRLRDSHETIASLRAQSPPVKYVIKTVEVESSKTKQALSESQARN 300 310 320 330 340 350 280 290 300 310 320 330 pF1KB4 QHLQEQVAMQRQVLKEMEQQLQSSHQLTARLRAQIAMYESELERAHGQMLEEMQSLEEDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QHLQEQVAMQRQVLKEMEQQLQSSHQLTARLRAQIAMYESELERAHGQMLEEMQSLEEDK 360 370 380 390 400 410 340 350 360 370 380 390 pF1KB4 NRAIEEAFARAQVEMKAVHENLAGVRTNLLTLQPALRTLTNDYNGLKRQVRGFPLLLQEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NRAIEEAFARAQVEMKAVHENLAGVRTNLLTLQPALRTLTNDYNGLKRQVRGFPLLLQEA 420 430 440 450 460 470 400 410 420 430 440 450 pF1KB4 LRSVKAEIGQAIEEVNSNNQELLRKYRRELQLRKKCHNELVRLKGNIRVIARVRPVTKED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LRSVKAEIGQAIEEVNSNNQELLRKYRRELQLRKKCHNELVRLKGNIRVIARVRPVTKED 480 490 500 510 520 530 460 470 480 490 500 510 pF1KB4 GEGPEATNAVTFDADDDSIIHLLHKGKPVSFELDKVFSPQASQQDVFQEVQALVTSCIDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GEGPEATNAVTFDADDDSIIHLLHKGKPVSFELDKVFSPQASQQDVFQEVQALVTSCIDG 540 550 560 570 580 590 520 530 540 550 560 570 pF1KB4 FNVCIFAYGQTGAGKTYTMEGTAENPGINQRALQLLFSEVQEKASDWEYTITVSAAEIYN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FNVCIFAYGQTGAGKTYTMEGTAENPGINQRALQLLFSEVQEKASDWEYTITVSAAEIYN 600 610 620 630 640 650 580 590 600 610 620 630 pF1KB4 EVLRDLLGKEPQEKLEIRLCPDGSGQLYVPGLTEFQVQSVDDINKVFEFGHTNRTTEFTN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EVLRDLLGKEPQEKLEIRLCPDGSGQLYVPGLTEFQVQSVDDINKVFEFGHTNRTTEFTN 660 670 680 690 700 710 640 650 660 670 680 690 pF1KB4 LNEHSSRSHALLIVTVRGVDCSTGLRTTGKLNLVDLAGSERVGKSGAEGSRLREAQHINK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LNEHSSRSHALLIVTVRGVDCSTGLRTTGKLNLVDLAGSERVGKSGAEGSRLREAQHINK 720 730 740 750 760 770 700 710 720 730 740 750 pF1KB4 SLSALGDVIAALRSRQGHVPFRNSKLTYLLQDSLSGDSKTLMVVQVSPVEKNTSETLYSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SLSALGDVIAALRSRQGHVPFRNSKLTYLLQDSLSGDSKTLMVVQVSPVEKNTSETLYSL 780 790 800 810 820 830 760 770 780 790 800 810 pF1KB4 KFAERVRSVELGPGLRRAELGSWSSQEHLEWEPACQTPQPSARAHSAPSSGTSSRPGSIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KFAERVRSVELGPGLRRAELGSWSSQEHLEWEPACQTPQPSARAHSAPSSGTSSRPGSIR 840 850 860 870 880 890 820 pF1KB4 RKLQPSA :::::: XP_016 RKLQPSGKSRPLPV 900 910 >>XP_006721251 (OMIM: 604535) PREDICTED: kinesin-like pr (1022 aa) initn: 4621 init1: 4621 opt: 4629 Z-score: 2397.9 bits: 455.0 E(85289): 8e-127 Smith-Waterman score: 4629; 95.5% identity (97.4% similar) in 763 aa overlap (68-825:255-1014) 40 50 60 70 80 90 pF1KB4 APASPAARPFPHTGPGRLRTGRGKDTPVCGDEDSSARSA-----ARPALAQCRALSVDWA : :..: :. . .:. : . ... . XP_006 RMVEAMSQLQDEKTQLQEELVVLQERLALRDSDQQATSTQLQNQVDASLSACWGRDLSTS 230 240 250 260 270 280 100 110 120 130 140 150 pF1KB4 GPGSPHGLYLTLQVEHLKEKLISQAQEVSRLRSELGGTDLEKHRDLLMVENERLRQEMRR : . :. .:::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GSQGEPGF---MQVEHLKEKLISQAQEVSRLRSELGGTDLEKHRDLLMVENERLRQEMRR 290 300 310 320 330 340 160 170 180 190 200 210 pF1KB4 CEAELQELRTKPAGPCPGCEHSQESAQLRDKLSQLQLEMAESKGMLSELNLEVQQKTDRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 CEAELQELRTKPAGPCPGCEHSQESAQLRDKLSQLQLEMAESKGMLSELNLEVQQKTDRL 350 360 370 380 390 400 220 230 240 250 260 270 pF1KB4 AEVELRLKDCLAEKAQEEERLSRRLRDSHETIASLRAQSPPVKYVIKTVEVESSKTKQAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AEVELRLKDCLAEKAQEEERLSRRLRDSHETIASLRAQSPPVKYVIKTVEVESSKTKQAL 410 420 430 440 450 460 280 290 300 310 320 330 pF1KB4 SESQARNQHLQEQVAMQRQVLKEMEQQLQSSHQLTARLRAQIAMYESELERAHGQMLEEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SESQARNQHLQEQVAMQRQVLKEMEQQLQSSHQLTARLRAQIAMYESELERAHGQMLEEM 470 480 490 500 510 520 340 350 360 370 380 390 pF1KB4 QSLEEDKNRAIEEAFARAQVEMKAVHENLAGVRTNLLTLQPALRTLTNDYNGLKRQVRGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QSLEEDKNRAIEEAFARAQVEMKAVHENLAGVRTNLLTLQPALRTLTNDYNGLKRQVRGF 530 540 550 560 570 580 400 410 420 430 440 450 pF1KB4 PLLLQEALRSVKAEIGQAIEEVNSNNQELLRKYRRELQLRKKCHNELVRLKGNIRVIARV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PLLLQEALRSVKAEIGQAIEEVNSNNQELLRKYRRELQLRKKCHNELVRLKGNIRVIARV 590 600 610 620 630 640 460 470 480 490 500 510 pF1KB4 RPVTKEDGEGPEATNAVTFDADDDSIIHLLHKGKPVSFELDKVFSPQASQQDVFQEVQAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RPVTKEDGEGPEATNAVTFDADDDSIIHLLHKGKPVSFELDKVFSPQASQQDVFQEVQAL 650 660 670 680 690 700 520 530 540 550 560 570 pF1KB4 VTSCIDGFNVCIFAYGQTGAGKTYTMEGTAENPGINQRALQLLFSEVQEKASDWEYTITV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VTSCIDGFNVCIFAYGQTGAGKTYTMEGTAENPGINQRALQLLFSEVQEKASDWEYTITV 710 720 730 740 750 760 580 590 600 610 620 630 pF1KB4 SAAEIYNEVLRDLLGKEPQEKLEIRLCPDGSGQLYVPGLTEFQVQSVDDINKVFEFGHTN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SAAEIYNEVLRDLLGKEPQEKLEIRLCPDGSGQLYVPGLTEFQVQSVDDINKVFEFGHTN 770 780 790 800 810 820 640 650 660 670 680 690 pF1KB4 RTTEFTNLNEHSSRSHALLIVTVRGVDCSTGLRTTGKLNLVDLAGSERVGKSGAEGSRLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RTTEFTNLNEHSSRSHALLIVTVRGVDCSTGLRTTGKLNLVDLAGSERVGKSGAEGSRLR 830 840 850 860 870 880 700 710 720 730 740 750 pF1KB4 EAQHINKSLSALGDVIAALRSRQGHVPFRNSKLTYLLQDSLSGDSKTLMVVQVSPVEKNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EAQHINKSLSALGDVIAALRSRQGHVPFRNSKLTYLLQDSLSGDSKTLMVVQVSPVEKNT 890 900 910 920 930 940 760 770 780 790 800 810 pF1KB4 SETLYSLKFAERVRSVELGPGLRRAELGSWSSQEHLEWEPACQTPQPSARAHSAPSSGTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SETLYSLKFAERVRSVELGPGLRRAELGSWSSQEHLEWEPACQTPQPSARAHSAPSSGTS 950 960 970 980 990 1000 820 pF1KB4 SRPGSIRRKLQPSA ::::::::::::: XP_006 SRPGSIRRKLQPSGKSRPLPV 1010 1020 >-- initn: 759 init1: 759 opt: 782 Z-score: 422.9 bits: 89.5 E(85289): 8.1e-17 Smith-Waterman score: 782; 65.2% identity (76.1% similar) in 201 aa overlap (1-191:50-244) 10 20 30 pF1KB4 MVPSRRTWNLGATPSLRGLWRVGRAPEPEP :::::::::::::::::::::::::::::: XP_006 RHQETLRLEAGVPEQCKAAWCPEEAAEPQAMVPSRRTWNLGATPSLRGLWRVGRAPEPEP 20 30 40 50 60 70 40 50 60 70 80 90 pF1KB4 GMARPAPAPASPAARPFPHTGPGRLRTGRGKDTPVCGDEDSSARSAARPALAQCRALSVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GMARPAPAPASPAARPFPHTGPGRLRTGRGKDTPVCGDEDSSARSAARPALAQCRALSVD 80 90 100 110 120 130 100 110 120 130 140 pF1KB4 WAGPGSPHGLYLTLQVEHLKEK-LISQAQEVS--RL--RSELGGTDLEKHRD---LLMVE ::::::::::::::: . :..: ::.: .. .: :. . .. :. . :: XP_006 WAGPGSPHGLYLTLQ-QALQDKGCKSQSQGTKEEKLWKRQAPAPRRAREAREAGGTMNVE 140 150 160 170 180 190 150 160 170 180 190 200 pF1KB4 NERLRQE-MRRCEAELQELRTKPAGPCPGCEHSQES-AQLRDKLSQLQLEMAESKGMLSE : : ::: . . : : : . :. .::.:. .::: :. XP_006 NTGGRLFGSRRCSSL-----SGPPGAAPMVLRMVEAMSQLQDEKTQLQEELVVLQERLAL 200 210 220 230 240 250 210 220 230 240 250 260 pF1KB4 LNLEVQQKTDRLAEVELRLKDCLAEKAQEEERLSRRLRDSHETIASLRAQSPPVKYVIKT XP_006 RDSDQQATSTQLQNQVDASLSACWGRDLSTSGSQGEPGFMQVEHLKEKLISQAQEVSRLR 260 270 280 290 300 310 826 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 14:33:11 2016 done: Thu Nov 3 14:33:13 2016 Total Scan time: 12.880 Total Display time: 0.280 Function used was FASTA [36.3.4 Apr, 2011]