Result of FASTA (omim) for
pF1KB4166
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB4166, 394 aa
1>>>pF1KB4166 394 - 394 aa - 394 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.8172+/-0.000372; mu= 15.2890+/- 0.023
mean_var=88.8553+/-18.574, 0's: 0 Z-trim(114.2): 87 B-trim: 941 in 1/56
Lambda= 0.136061
statistics sampled from 23768 (23860) to 23768 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.638), E-opt: 0.2 (0.28), width: 16
Scan time: 5.770
The best scores are: opt bits E(85289)
NP_001128714 (OMIM: 601455,605262) protein NDRG1 i ( 394) 2647 529.7 4.7e-150
NP_006087 (OMIM: 601455,605262) protein NDRG1 isof ( 394) 2647 529.7 4.7e-150
NP_001245361 (OMIM: 601455,605262) protein NDRG1 i ( 328) 2212 444.2 2.1e-124
NP_001245362 (OMIM: 601455,605262) protein NDRG1 i ( 313) 2097 421.6 1.2e-117
NP_114402 (OMIM: 605273) protein NDRG3 isoform a [ ( 375) 1622 328.5 1.7e-89
XP_016883468 (OMIM: 605273) PREDICTED: protein NDR ( 375) 1622 328.5 1.7e-89
XP_016883467 (OMIM: 605273) PREDICTED: protein NDR ( 388) 1596 323.4 5.9e-88
XP_006723900 (OMIM: 605273) PREDICTED: protein NDR ( 388) 1596 323.4 5.9e-88
XP_016883469 (OMIM: 605273) PREDICTED: protein NDR ( 366) 1545 313.3 5.8e-85
NP_071922 (OMIM: 605273) protein NDRG3 isoform b [ ( 363) 1544 313.1 6.6e-85
XP_011527228 (OMIM: 605273) PREDICTED: protein NDR ( 345) 1542 312.7 8.4e-85
XP_006723901 (OMIM: 605273) PREDICTED: protein NDR ( 379) 1519 308.2 2.1e-83
XP_011527229 (OMIM: 605273) PREDICTED: protein NDR ( 376) 1518 308.0 2.3e-83
XP_011527227 (OMIM: 605273) PREDICTED: protein NDR ( 358) 1516 307.6 3e-83
XP_016879079 (OMIM: 614463) PREDICTED: protein NDR ( 371) 1497 303.9 4e-82
NP_075061 (OMIM: 614463) protein NDRG4 isoform 1 [ ( 371) 1497 303.9 4e-82
NP_065198 (OMIM: 614463) protein NDRG4 isoform 1 [ ( 371) 1497 303.9 4e-82
XP_016879078 (OMIM: 614463) PREDICTED: protein NDR ( 384) 1497 303.9 4.1e-82
NP_001123959 (OMIM: 614463) protein NDRG4 isoform ( 391) 1497 303.9 4.2e-82
NP_001229763 (OMIM: 614463) protein NDRG4 isoform ( 357) 1485 301.6 2e-81
XP_016879077 (OMIM: 614463) PREDICTED: protein NDR ( 389) 1485 301.6 2.1e-81
XP_016879071 (OMIM: 614463) PREDICTED: protein NDR ( 389) 1485 301.6 2.1e-81
XP_016879075 (OMIM: 614463) PREDICTED: protein NDR ( 402) 1485 301.6 2.2e-81
XP_016879074 (OMIM: 614463) PREDICTED: protein NDR ( 409) 1485 301.6 2.2e-81
NP_001229762 (OMIM: 614463) protein NDRG4 isoform ( 369) 1484 301.4 2.4e-81
XP_011521594 (OMIM: 614463) PREDICTED: protein NDR ( 401) 1484 301.4 2.5e-81
XP_016879076 (OMIM: 614463) PREDICTED: protein NDR ( 401) 1484 301.4 2.5e-81
XP_016879073 (OMIM: 614463) PREDICTED: protein NDR ( 421) 1484 301.4 2.6e-81
NP_001229765 (OMIM: 614463) protein NDRG4 isoform ( 339) 1477 300.0 5.7e-81
XP_011515093 (OMIM: 601455,605262) PREDICTED: prot ( 411) 1422 289.2 1.2e-77
XP_006721323 (OMIM: 614463) PREDICTED: protein NDR ( 384) 1394 283.7 5.1e-76
XP_011521595 (OMIM: 614463) PREDICTED: protein NDR ( 384) 1394 283.7 5.1e-76
XP_011521596 (OMIM: 614463) PREDICTED: protein NDR ( 384) 1394 283.7 5.1e-76
XP_006721322 (OMIM: 614463) PREDICTED: protein NDR ( 397) 1394 283.7 5.2e-76
XP_006721320 (OMIM: 614463) PREDICTED: protein NDR ( 404) 1394 283.7 5.3e-76
XP_006721325 (OMIM: 614463) PREDICTED: protein NDR ( 370) 1382 281.3 2.5e-75
XP_011521593 (OMIM: 614463) PREDICTED: protein NDR ( 402) 1382 281.4 2.7e-75
XP_006721321 (OMIM: 614463) PREDICTED: protein NDR ( 402) 1382 281.4 2.7e-75
XP_006721317 (OMIM: 614463) PREDICTED: protein NDR ( 422) 1382 281.4 2.8e-75
XP_006721324 (OMIM: 614463) PREDICTED: protein NDR ( 382) 1381 281.2 3e-75
XP_011521592 (OMIM: 614463) PREDICTED: protein NDR ( 414) 1381 281.2 3.1e-75
XP_006721319 (OMIM: 614463) PREDICTED: protein NDR ( 414) 1381 281.2 3.1e-75
XP_006721316 (OMIM: 614463) PREDICTED: protein NDR ( 427) 1381 281.2 3.2e-75
XP_006721315 (OMIM: 614463) PREDICTED: protein NDR ( 434) 1381 281.2 3.3e-75
NP_001229764 (OMIM: 614463) protein NDRG4 isoform ( 352) 1374 279.8 7.2e-75
XP_011515094 (OMIM: 601455,605262) PREDICTED: prot ( 205) 1347 274.3 1.8e-73
NP_963832 (OMIM: 605272) protein NDRG2 isoform b [ ( 357) 1339 272.9 8.5e-73
XP_011535301 (OMIM: 605272) PREDICTED: protein NDR ( 357) 1339 272.9 8.5e-73
XP_011535304 (OMIM: 605272) PREDICTED: protein NDR ( 357) 1339 272.9 8.5e-73
NP_963294 (OMIM: 605272) protein NDRG2 isoform b [ ( 357) 1339 272.9 8.5e-73
>>NP_001128714 (OMIM: 601455,605262) protein NDRG1 isofo (394 aa)
initn: 2647 init1: 2647 opt: 2647 Z-score: 2814.9 bits: 529.7 E(85289): 4.7e-150
Smith-Waterman score: 2647; 100.0% identity (100.0% similar) in 394 aa overlap (1-394:1-394)
10 20 30 40 50 60
pF1KB4 MSREMQDVDLAEVKPLVEKGETITGLLQEFDVQEQDIETLHGSVHVTLCGTPKGNRPVIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSREMQDVDLAEVKPLVEKGETITGLLQEFDVQEQDIETLHGSVHVTLCGTPKGNRPVIL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 TYHDIGMNHKTCYNPLFNYEDMQEITQHFAVCHVDAPGQQDGAASFPAGYMYPSMDQLAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TYHDIGMNHKTCYNPLFNYEDMQEITQHFAVCHVDAPGQQDGAASFPAGYMYPSMDQLAE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 MLPGVLQQFGLKSIIGMGTGAGAYILTRFALNNPEMVEGLVLINVNPCAEGWMDWAASKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLPGVLQQFGLKSIIGMGTGAGAYILTRFALNNPEMVEGLVLINVNPCAEGWMDWAASKI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 SGWTQALPDMVVSHLFGKEEMQSNVEVVHTYRQHIVNDMNPGNLHLFINAYNSRRDLEIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGWTQALPDMVVSHLFGKEEMQSNVEVVHTYRQHIVNDMNPGNLHLFINAYNSRRDLEIE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 RPMPGTHTVTLQCPALLVVGDSSPAVDAVVECNSKLDPTKTTLLKMADCGGLPQISQPAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RPMPGTHTVTLQCPALLVVGDSSPAVDAVVECNSKLDPTKTTLLKMADCGGLPQISQPAK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 LAEAFKYFVQGMGYMPSASMTRLMRSRTASGSSVTSLDGTRSRSHTSEGTRSRSHTSEGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAEAFKYFVQGMGYMPSASMTRLMRSRTASGSSVTSLDGTRSRSHTSEGTRSRSHTSEGT
310 320 330 340 350 360
370 380 390
pF1KB4 RSRSHTSEGAHLDITPNSGAAGNSAGPKSMEVSC
::::::::::::::::::::::::::::::::::
NP_001 RSRSHTSEGAHLDITPNSGAAGNSAGPKSMEVSC
370 380 390
>>NP_006087 (OMIM: 601455,605262) protein NDRG1 isoform (394 aa)
initn: 2647 init1: 2647 opt: 2647 Z-score: 2814.9 bits: 529.7 E(85289): 4.7e-150
Smith-Waterman score: 2647; 100.0% identity (100.0% similar) in 394 aa overlap (1-394:1-394)
10 20 30 40 50 60
pF1KB4 MSREMQDVDLAEVKPLVEKGETITGLLQEFDVQEQDIETLHGSVHVTLCGTPKGNRPVIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MSREMQDVDLAEVKPLVEKGETITGLLQEFDVQEQDIETLHGSVHVTLCGTPKGNRPVIL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 TYHDIGMNHKTCYNPLFNYEDMQEITQHFAVCHVDAPGQQDGAASFPAGYMYPSMDQLAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 TYHDIGMNHKTCYNPLFNYEDMQEITQHFAVCHVDAPGQQDGAASFPAGYMYPSMDQLAE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 MLPGVLQQFGLKSIIGMGTGAGAYILTRFALNNPEMVEGLVLINVNPCAEGWMDWAASKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MLPGVLQQFGLKSIIGMGTGAGAYILTRFALNNPEMVEGLVLINVNPCAEGWMDWAASKI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 SGWTQALPDMVVSHLFGKEEMQSNVEVVHTYRQHIVNDMNPGNLHLFINAYNSRRDLEIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 SGWTQALPDMVVSHLFGKEEMQSNVEVVHTYRQHIVNDMNPGNLHLFINAYNSRRDLEIE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 RPMPGTHTVTLQCPALLVVGDSSPAVDAVVECNSKLDPTKTTLLKMADCGGLPQISQPAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 RPMPGTHTVTLQCPALLVVGDSSPAVDAVVECNSKLDPTKTTLLKMADCGGLPQISQPAK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 LAEAFKYFVQGMGYMPSASMTRLMRSRTASGSSVTSLDGTRSRSHTSEGTRSRSHTSEGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LAEAFKYFVQGMGYMPSASMTRLMRSRTASGSSVTSLDGTRSRSHTSEGTRSRSHTSEGT
310 320 330 340 350 360
370 380 390
pF1KB4 RSRSHTSEGAHLDITPNSGAAGNSAGPKSMEVSC
::::::::::::::::::::::::::::::::::
NP_006 RSRSHTSEGAHLDITPNSGAAGNSAGPKSMEVSC
370 380 390
>>NP_001245361 (OMIM: 601455,605262) protein NDRG1 isofo (328 aa)
initn: 2212 init1: 2212 opt: 2212 Z-score: 2354.6 bits: 444.2 E(85289): 2.1e-124
Smith-Waterman score: 2212; 100.0% identity (100.0% similar) in 328 aa overlap (67-394:1-328)
40 50 60 70 80 90
pF1KB4 IETLHGSVHVTLCGTPKGNRPVILTYHDIGMNHKTCYNPLFNYEDMQEITQHFAVCHVDA
::::::::::::::::::::::::::::::
NP_001 MNHKTCYNPLFNYEDMQEITQHFAVCHVDA
10 20 30
100 110 120 130 140 150
pF1KB4 PGQQDGAASFPAGYMYPSMDQLAEMLPGVLQQFGLKSIIGMGTGAGAYILTRFALNNPEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PGQQDGAASFPAGYMYPSMDQLAEMLPGVLQQFGLKSIIGMGTGAGAYILTRFALNNPEM
40 50 60 70 80 90
160 170 180 190 200 210
pF1KB4 VEGLVLINVNPCAEGWMDWAASKISGWTQALPDMVVSHLFGKEEMQSNVEVVHTYRQHIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VEGLVLINVNPCAEGWMDWAASKISGWTQALPDMVVSHLFGKEEMQSNVEVVHTYRQHIV
100 110 120 130 140 150
220 230 240 250 260 270
pF1KB4 NDMNPGNLHLFINAYNSRRDLEIERPMPGTHTVTLQCPALLVVGDSSPAVDAVVECNSKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NDMNPGNLHLFINAYNSRRDLEIERPMPGTHTVTLQCPALLVVGDSSPAVDAVVECNSKL
160 170 180 190 200 210
280 290 300 310 320 330
pF1KB4 DPTKTTLLKMADCGGLPQISQPAKLAEAFKYFVQGMGYMPSASMTRLMRSRTASGSSVTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DPTKTTLLKMADCGGLPQISQPAKLAEAFKYFVQGMGYMPSASMTRLMRSRTASGSSVTS
220 230 240 250 260 270
340 350 360 370 380 390
pF1KB4 LDGTRSRSHTSEGTRSRSHTSEGTRSRSHTSEGAHLDITPNSGAAGNSAGPKSMEVSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDGTRSRSHTSEGTRSRSHTSEGTRSRSHTSEGAHLDITPNSGAAGNSAGPKSMEVSC
280 290 300 310 320
>>NP_001245362 (OMIM: 601455,605262) protein NDRG1 isofo (313 aa)
initn: 2097 init1: 2097 opt: 2097 Z-score: 2232.9 bits: 421.6 E(85289): 1.2e-117
Smith-Waterman score: 2097; 100.0% identity (100.0% similar) in 313 aa overlap (82-394:1-313)
60 70 80 90 100 110
pF1KB4 PKGNRPVILTYHDIGMNHKTCYNPLFNYEDMQEITQHFAVCHVDAPGQQDGAASFPAGYM
::::::::::::::::::::::::::::::
NP_001 MQEITQHFAVCHVDAPGQQDGAASFPAGYM
10 20 30
120 130 140 150 160 170
pF1KB4 YPSMDQLAEMLPGVLQQFGLKSIIGMGTGAGAYILTRFALNNPEMVEGLVLINVNPCAEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YPSMDQLAEMLPGVLQQFGLKSIIGMGTGAGAYILTRFALNNPEMVEGLVLINVNPCAEG
40 50 60 70 80 90
180 190 200 210 220 230
pF1KB4 WMDWAASKISGWTQALPDMVVSHLFGKEEMQSNVEVVHTYRQHIVNDMNPGNLHLFINAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WMDWAASKISGWTQALPDMVVSHLFGKEEMQSNVEVVHTYRQHIVNDMNPGNLHLFINAY
100 110 120 130 140 150
240 250 260 270 280 290
pF1KB4 NSRRDLEIERPMPGTHTVTLQCPALLVVGDSSPAVDAVVECNSKLDPTKTTLLKMADCGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NSRRDLEIERPMPGTHTVTLQCPALLVVGDSSPAVDAVVECNSKLDPTKTTLLKMADCGG
160 170 180 190 200 210
300 310 320 330 340 350
pF1KB4 LPQISQPAKLAEAFKYFVQGMGYMPSASMTRLMRSRTASGSSVTSLDGTRSRSHTSEGTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPQISQPAKLAEAFKYFVQGMGYMPSASMTRLMRSRTASGSSVTSLDGTRSRSHTSEGTR
220 230 240 250 260 270
360 370 380 390
pF1KB4 SRSHTSEGTRSRSHTSEGAHLDITPNSGAAGNSAGPKSMEVSC
:::::::::::::::::::::::::::::::::::::::::::
NP_001 SRSHTSEGTRSRSHTSEGAHLDITPNSGAAGNSAGPKSMEVSC
280 290 300 310
>>NP_114402 (OMIM: 605273) protein NDRG3 isoform a [Homo (375 aa)
initn: 1651 init1: 1130 opt: 1622 Z-score: 1727.9 bits: 328.5 E(85289): 1.7e-89
Smith-Waterman score: 1622; 65.3% identity (86.8% similar) in 372 aa overlap (4-368:3-372)
10 20 30 40 50 60
pF1KB4 MSREMQDVDLAEVKPLVEKGETITGLLQEFDVQEQDIETLHGSVHVTLCGTPKGNRPVIL
:.:::.:.:.:::.. .. : .:.:: ::.:::: :: ::::. : :::::::::
NP_114 MDELQDVQLTEIKPLLND-KNGTRNFQDFDCQEHDIETTHGVVHVTIRGLPKGNRPVIL
10 20 30 40 50
70 80 90 100 110 120
pF1KB4 TYHDIGMNHKTCYNPLFNYEDMQEITQHFAVCHVDAPGQQDGAASFPAGYMYPSMDQLAE
::::::.:::.:.: .::.:::::::::::::::::::::.:: :::.::.::.::.:::
NP_114 TYHDIGLNHKSCFNAFFNFEDMQEITQHFAVCHVDAPGQQEGAPSFPTGYQYPTMDELAE
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB4 MLPGVLQQFGLKSIIGMGTGAGAYILTRFALNNPEMVEGLVLINVNPCAEGWMDWAASKI
::: :: ...::::::.:.:::::::.:::::.::.:::::::::.:::.::.::::::.
NP_114 MLPPVLTHLSLKSIIGIGVGAGAYILSRFALNHPELVEGLVLINVDPCAKGWIDWAASKL
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB4 SGWTQALPDMVVSHLFGKEEMQSNVEVVHTYRQHIVNDMNPGNLHLFINAYNSRRDLEIE
:: : . :....: ::.::.:.:.....:::.::..:.: ::.::.:.::.:::::::
NP_114 SGLTTNVVDIILAHHFGQEELQANLDLIQTYRMHIAQDINQDNLQLFLNSYNGRRDLEIE
180 190 200 210 220 230
250 260 270 280 290
pF1KB4 RPMPGTH---TVTLQCPALLVVGDSSPAVDAVVECNSKLDPTKTTLLKMADCGGLPQISQ
::. : . . ::.: .::::::.::::.:::::::.:.: .::::::::::::::. :
NP_114 RPILGQNDNKSKTLKCSTLLVVGDNSPAVEAVVECNSRLNPINTTLLKMADCGGLPQVVQ
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB4 PAKLAEAFKYFVQGMGYMPSASMTRLMRSRTAS-GSSVTSLDGTRSRSHTS---EGTRSR
:.::.::::::.:::::.:::::::: :::: : .::. : .. ::: :: .::. .
NP_114 PGKLTEAFKYFLQGMGYIPSASMTRLARSRTHSTSSSLGSGESPFSRSVTSNQSDGTQ-E
300 310 320 330 340 350
360 370 380 390
pF1KB4 SHTSEGTRSRSHTSEGAHLDITPNSGAAGNSAGPKSMEVSC
: : . .: .: :
NP_114 SCESPDVLDRHQTMEVSC
360 370
>>XP_016883468 (OMIM: 605273) PREDICTED: protein NDRG3 i (375 aa)
initn: 1651 init1: 1130 opt: 1622 Z-score: 1727.9 bits: 328.5 E(85289): 1.7e-89
Smith-Waterman score: 1622; 65.3% identity (86.8% similar) in 372 aa overlap (4-368:3-372)
10 20 30 40 50 60
pF1KB4 MSREMQDVDLAEVKPLVEKGETITGLLQEFDVQEQDIETLHGSVHVTLCGTPKGNRPVIL
:.:::.:.:.:::.. .. : .:.:: ::.:::: :: ::::. : :::::::::
XP_016 MDELQDVQLTEIKPLLND-KNGTRNFQDFDCQEHDIETTHGVVHVTIRGLPKGNRPVIL
10 20 30 40 50
70 80 90 100 110 120
pF1KB4 TYHDIGMNHKTCYNPLFNYEDMQEITQHFAVCHVDAPGQQDGAASFPAGYMYPSMDQLAE
::::::.:::.:.: .::.:::::::::::::::::::::.:: :::.::.::.::.:::
XP_016 TYHDIGLNHKSCFNAFFNFEDMQEITQHFAVCHVDAPGQQEGAPSFPTGYQYPTMDELAE
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB4 MLPGVLQQFGLKSIIGMGTGAGAYILTRFALNNPEMVEGLVLINVNPCAEGWMDWAASKI
::: :: ...::::::.:.:::::::.:::::.::.:::::::::.:::.::.::::::.
XP_016 MLPPVLTHLSLKSIIGIGVGAGAYILSRFALNHPELVEGLVLINVDPCAKGWIDWAASKL
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB4 SGWTQALPDMVVSHLFGKEEMQSNVEVVHTYRQHIVNDMNPGNLHLFINAYNSRRDLEIE
:: : . :....: ::.::.:.:.....:::.::..:.: ::.::.:.::.:::::::
XP_016 SGLTTNVVDIILAHHFGQEELQANLDLIQTYRMHIAQDINQDNLQLFLNSYNGRRDLEIE
180 190 200 210 220 230
250 260 270 280 290
pF1KB4 RPMPGTH---TVTLQCPALLVVGDSSPAVDAVVECNSKLDPTKTTLLKMADCGGLPQISQ
::. : . . ::.: .::::::.::::.:::::::.:.: .::::::::::::::. :
XP_016 RPILGQNDNKSKTLKCSTLLVVGDNSPAVEAVVECNSRLNPINTTLLKMADCGGLPQVVQ
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB4 PAKLAEAFKYFVQGMGYMPSASMTRLMRSRTAS-GSSVTSLDGTRSRSHTS---EGTRSR
:.::.::::::.:::::.:::::::: :::: : .::. : .. ::: :: .::. .
XP_016 PGKLTEAFKYFLQGMGYIPSASMTRLARSRTHSTSSSLGSGESPFSRSVTSNQSDGTQ-E
300 310 320 330 340 350
360 370 380 390
pF1KB4 SHTSEGTRSRSHTSEGAHLDITPNSGAAGNSAGPKSMEVSC
: : . .: .: :
XP_016 SCESPDVLDRHQTMEVSC
360 370
>>XP_016883467 (OMIM: 605273) PREDICTED: protein NDRG3 i (388 aa)
initn: 1656 init1: 1130 opt: 1596 Z-score: 1700.1 bits: 323.4 E(85289): 5.9e-88
Smith-Waterman score: 1596; 60.8% identity (84.8% similar) in 395 aa overlap (4-394:3-388)
10 20 30 40 50 60
pF1KB4 MSREMQDVDLAEVKPLVEKGETITGLLQEFDVQEQDIETLHGSVHVTLCGTPKGNRPVIL
:.:::.:.:.:::.. .. : .:.:: ::.:::: :: ::::. : :::::::::
XP_016 MDELQDVQLTEIKPLLND-KNGTRNFQDFDCQEHDIETTHGVVHVTIRGLPKGNRPVIL
10 20 30 40 50
70 80 90 100 110 120
pF1KB4 TYHDIGMNHKTCYNPLFNYEDMQEITQHFAVCHVDAPGQQDGAASFPAGYMYPSMDQLAE
::::::.:::.:.: .::.:::::::::::::::::::::.:: :::.::.::.::.:::
XP_016 TYHDIGLNHKSCFNAFFNFEDMQEITQHFAVCHVDAPGQQEGAPSFPTGYQYPTMDELAE
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB4 MLPGVLQQFGLKSIIGMGTGAGAYILTRFALNNPEMVEGLVLINVNPCAEGWMDWAASKI
::: :: ...::::::.:.:::::::.:::::.::.:::::::::.:::.::.::::::.
XP_016 MLPPVLTHLSLKSIIGIGVGAGAYILSRFALNHPELVEGLVLINVDPCAKGWIDWAASKL
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB4 SGWTQALPDMVVSHLFGKEEMQSNVEVVHTYRQHIVNDMNPGNLHLFINAYNSRRDLEIE
:: : . :....: ::.::.:.:.....:::.::..:.: ::.::.:.::.:::::::
XP_016 SGLTTNVVDIILAHHFGQEELQANLDLIQTYRMHIAQDINQDNLQLFLNSYNGRRDLEIE
180 190 200 210 220 230
250 260 270 280 290
pF1KB4 RPMPGTH---TVTLQCPALLVVGDSSPAVDAVVECNSKLDPTKTTLLKMADCGGLPQISQ
::. : . . ::.: .::::::.::::.:::::::.:.: .::::::::::::::. :
XP_016 RPILGQNDNKSKTLKCSTLLVVGDNSPAVEAVVECNSRLNPINTTLLKMADCGGLPQVVQ
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB4 PAKLAEAFKYFVQGMGYMPSASMTRLMRSRTASGSSVTSLDGTRSRSHTSEGTRSRSHTS
:.::.::::::.:::::.: .....: .... ..:.: : .:::.:. : : ..
XP_016 PGKLTEAFKYFLQGMGYIPYVQLSHL-STESVPSASMTRL--ARSRTHS---TSSSLGSG
300 310 320 330 340 350
360 370 380 390
pF1KB4 EGTRSRSHTSEGAHLDITPNSGAAGNSAG-PKSMEVSC
:. ::: ::. . : : .: . . ..:::::
XP_016 ESPFSRSVTSNQS--DGTQESCESPDVLDRHQTMEVSC
360 370 380
>>XP_006723900 (OMIM: 605273) PREDICTED: protein NDRG3 i (388 aa)
initn: 1656 init1: 1130 opt: 1596 Z-score: 1700.1 bits: 323.4 E(85289): 5.9e-88
Smith-Waterman score: 1596; 60.8% identity (84.8% similar) in 395 aa overlap (4-394:3-388)
10 20 30 40 50 60
pF1KB4 MSREMQDVDLAEVKPLVEKGETITGLLQEFDVQEQDIETLHGSVHVTLCGTPKGNRPVIL
:.:::.:.:.:::.. .. : .:.:: ::.:::: :: ::::. : :::::::::
XP_006 MDELQDVQLTEIKPLLND-KNGTRNFQDFDCQEHDIETTHGVVHVTIRGLPKGNRPVIL
10 20 30 40 50
70 80 90 100 110 120
pF1KB4 TYHDIGMNHKTCYNPLFNYEDMQEITQHFAVCHVDAPGQQDGAASFPAGYMYPSMDQLAE
::::::.:::.:.: .::.:::::::::::::::::::::.:: :::.::.::.::.:::
XP_006 TYHDIGLNHKSCFNAFFNFEDMQEITQHFAVCHVDAPGQQEGAPSFPTGYQYPTMDELAE
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB4 MLPGVLQQFGLKSIIGMGTGAGAYILTRFALNNPEMVEGLVLINVNPCAEGWMDWAASKI
::: :: ...::::::.:.:::::::.:::::.::.:::::::::.:::.::.::::::.
XP_006 MLPPVLTHLSLKSIIGIGVGAGAYILSRFALNHPELVEGLVLINVDPCAKGWIDWAASKL
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB4 SGWTQALPDMVVSHLFGKEEMQSNVEVVHTYRQHIVNDMNPGNLHLFINAYNSRRDLEIE
:: : . :....: ::.::.:.:.....:::.::..:.: ::.::.:.::.:::::::
XP_006 SGLTTNVVDIILAHHFGQEELQANLDLIQTYRMHIAQDINQDNLQLFLNSYNGRRDLEIE
180 190 200 210 220 230
250 260 270 280 290
pF1KB4 RPMPGTH---TVTLQCPALLVVGDSSPAVDAVVECNSKLDPTKTTLLKMADCGGLPQISQ
::. : . . ::.: .::::::.::::.:::::::.:.: .::::::::::::::. :
XP_006 RPILGQNDNKSKTLKCSTLLVVGDNSPAVEAVVECNSRLNPINTTLLKMADCGGLPQVVQ
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB4 PAKLAEAFKYFVQGMGYMPSASMTRLMRSRTASGSSVTSLDGTRSRSHTSEGTRSRSHTS
:.::.::::::.:::::.: .....: .... ..:.: : .:::.:. : : ..
XP_006 PGKLTEAFKYFLQGMGYIPYVQLSHL-STESVPSASMTRL--ARSRTHS---TSSSLGSG
300 310 320 330 340 350
360 370 380 390
pF1KB4 EGTRSRSHTSEGAHLDITPNSGAAGNSAG-PKSMEVSC
:. ::: ::. . : : .: . . ..:::::
XP_006 ESPFSRSVTSNQS--DGTQESCESPDVLDRHQTMEVSC
360 370 380
>>XP_016883469 (OMIM: 605273) PREDICTED: protein NDRG3 i (366 aa)
initn: 1579 init1: 1101 opt: 1545 Z-score: 1646.3 bits: 313.3 E(85289): 5.8e-85
Smith-Waterman score: 1545; 66.6% identity (87.5% similar) in 344 aa overlap (32-368:21-363)
10 20 30 40 50 60
pF1KB4 SREMQDVDLAEVKPLVEKGETITGLLQEFDVQEQDIETLHGSVHVTLCGTPKGNRPVILT
..:.:::: :: ::::. : ::::::::::
XP_016 MEFFSSCSFTRSRKICMPITMEEHDIETTHGVVHVTIRGLPKGNRPVILT
10 20 30 40 50
70 80 90 100 110 120
pF1KB4 YHDIGMNHKTCYNPLFNYEDMQEITQHFAVCHVDAPGQQDGAASFPAGYMYPSMDQLAEM
:::::.:::.:.: .::.:::::::::::::::::::::.:: :::.::.::.::.::::
XP_016 YHDIGLNHKSCFNAFFNFEDMQEITQHFAVCHVDAPGQQEGAPSFPTGYQYPTMDELAEM
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB4 LPGVLQQFGLKSIIGMGTGAGAYILTRFALNNPEMVEGLVLINVNPCAEGWMDWAASKIS
:: :: ...::::::.:.:::::::.:::::.::.:::::::::.:::.::.::::::.:
XP_016 LPPVLTHLSLKSIIGIGVGAGAYILSRFALNHPELVEGLVLINVDPCAKGWIDWAASKLS
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB4 GWTQALPDMVVSHLFGKEEMQSNVEVVHTYRQHIVNDMNPGNLHLFINAYNSRRDLEIER
: : . :....: ::.::.:.:.....:::.::..:.: ::.::.:.::.::::::::
XP_016 GLTTNVVDIILAHHFGQEELQANLDLIQTYRMHIAQDINQDNLQLFLNSYNGRRDLEIER
180 190 200 210 220 230
250 260 270 280 290
pF1KB4 PMPGTH---TVTLQCPALLVVGDSSPAVDAVVECNSKLDPTKTTLLKMADCGGLPQISQP
:. : . . ::.: .::::::.::::.:::::::.:.: .::::::::::::::. ::
XP_016 PILGQNDNKSKTLKCSTLLVVGDNSPAVEAVVECNSRLNPINTTLLKMADCGGLPQVVQP
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB4 AKLAEAFKYFVQGMGYMPSASMTRLMRSRTAS-GSSVTSLDGTRSRSHTS---EGTRSRS
.::.::::::.:::::.:::::::: :::: : .::. : .. ::: :: .::. .:
XP_016 GKLTEAFKYFLQGMGYIPSASMTRLARSRTHSTSSSLGSGESPFSRSVTSNQSDGTQ-ES
300 310 320 330 340
360 370 380 390
pF1KB4 HTSEGTRSRSHTSEGAHLDITPNSGAAGNSAGPKSMEVSC
: . .: .: :
XP_016 CESPDVLDRHQTMEVSC
350 360
>>NP_071922 (OMIM: 605273) protein NDRG3 isoform b [Homo (363 aa)
initn: 1578 init1: 1100 opt: 1544 Z-score: 1645.3 bits: 313.1 E(85289): 6.6e-85
Smith-Waterman score: 1573; 64.0% identity (84.7% similar) in 372 aa overlap (4-368:3-360)
10 20 30 40 50 60
pF1KB4 MSREMQDVDLAEVKPLVEKGETITGLLQEFDVQEQDIETLHGSVHVTLCGTPKGNRPVIL
:.:::.:.:.:::.. .:.:::: :: ::::. : :::::::::
NP_071 MDELQDVQLTEIKPLLND-------------KEHDIETTHGVVHVTIRGLPKGNRPVIL
10 20 30 40
70 80 90 100 110 120
pF1KB4 TYHDIGMNHKTCYNPLFNYEDMQEITQHFAVCHVDAPGQQDGAASFPAGYMYPSMDQLAE
::::::.:::.:.: .::.:::::::::::::::::::::.:: :::.::.::.::.:::
NP_071 TYHDIGLNHKSCFNAFFNFEDMQEITQHFAVCHVDAPGQQEGAPSFPTGYQYPTMDELAE
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB4 MLPGVLQQFGLKSIIGMGTGAGAYILTRFALNNPEMVEGLVLINVNPCAEGWMDWAASKI
::: :: ...::::::.:.:::::::.:::::.::.:::::::::.:::.::.::::::.
NP_071 MLPPVLTHLSLKSIIGIGVGAGAYILSRFALNHPELVEGLVLINVDPCAKGWIDWAASKL
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB4 SGWTQALPDMVVSHLFGKEEMQSNVEVVHTYRQHIVNDMNPGNLHLFINAYNSRRDLEIE
:: : . :....: ::.::.:.:.....:::.::..:.: ::.::.:.::.:::::::
NP_071 SGLTTNVVDIILAHHFGQEELQANLDLIQTYRMHIAQDINQDNLQLFLNSYNGRRDLEIE
170 180 190 200 210 220
250 260 270 280 290
pF1KB4 RPMPGTH---TVTLQCPALLVVGDSSPAVDAVVECNSKLDPTKTTLLKMADCGGLPQISQ
::. : . . ::.: .::::::.::::.:::::::.:.: .::::::::::::::. :
NP_071 RPILGQNDNKSKTLKCSTLLVVGDNSPAVEAVVECNSRLNPINTTLLKMADCGGLPQVVQ
230 240 250 260 270 280
300 310 320 330 340 350
pF1KB4 PAKLAEAFKYFVQGMGYMPSASMTRLMRSRTAS-GSSVTSLDGTRSRSHTS---EGTRSR
:.::.::::::.:::::.:::::::: :::: : .::. : .. ::: :: .::. .
NP_071 PGKLTEAFKYFLQGMGYIPSASMTRLARSRTHSTSSSLGSGESPFSRSVTSNQSDGTQ-E
290 300 310 320 330 340
360 370 380 390
pF1KB4 SHTSEGTRSRSHTSEGAHLDITPNSGAAGNSAGPKSMEVSC
: : . .: .: :
NP_071 SCESPDVLDRHQTMEVSC
350 360
394 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 05:41:11 2016 done: Sat Nov 5 05:41:12 2016
Total Scan time: 5.770 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]