FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4176, 451 aa 1>>>pF1KB4176 451 - 451 aa - 451 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.0548+/-0.000457; mu= 13.1897+/- 0.029 mean_var=72.1776+/-14.411, 0's: 0 Z-trim(108.5): 168 B-trim: 0 in 0/59 Lambda= 0.150964 statistics sampled from 16424 (16605) to 16424 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.543), E-opt: 0.2 (0.195), width: 16 Scan time: 8.370 The best scores are: opt bits E(85289) XP_016863472 (OMIM: 103780,137140) PREDICTED: gamm ( 451) 2974 657.6 1.9e-188 NP_000798 (OMIM: 103780,137140) gamma-aminobutyric ( 451) 2974 657.6 1.9e-188 NP_001107647 (OMIM: 103780,137140) gamma-aminobuty ( 451) 2974 657.6 1.9e-188 XP_016863471 (OMIM: 103780,137140) PREDICTED: gamm ( 451) 2974 657.6 1.9e-188 XP_005248137 (OMIM: 103780,137140) PREDICTED: gamm ( 396) 2434 540.0 4.3e-153 NP_001317619 (OMIM: 103780,137140) gamma-aminobuty ( 511) 2350 521.7 1.7e-147 XP_011511977 (OMIM: 103780,137140) PREDICTED: gamm ( 511) 2350 521.7 1.7e-147 NP_001121115 (OMIM: 137160,611136,615744) gamma-am ( 456) 2255 501.0 2.6e-141 NP_000797 (OMIM: 137160,611136,615744) gamma-amino ( 456) 2255 501.0 2.6e-141 NP_001121120 (OMIM: 137160,611136,615744) gamma-am ( 456) 2255 501.0 2.6e-141 NP_001121117 (OMIM: 137160,611136,615744) gamma-am ( 456) 2255 501.0 2.6e-141 NP_001121116 (OMIM: 137160,611136,615744) gamma-am ( 456) 2255 501.0 2.6e-141 NP_000801 (OMIM: 137142) gamma-aminobutyric acid r ( 462) 2156 479.5 8.3e-135 NP_001158509 (OMIM: 137142) gamma-aminobutyric aci ( 462) 2156 479.5 8.3e-135 XP_005268315 (OMIM: 137142) PREDICTED: gamma-amino ( 462) 2156 479.5 8.3e-135 XP_006720522 (OMIM: 137142) PREDICTED: gamma-amino ( 462) 2156 479.5 8.3e-135 NP_000799 (OMIM: 305660) gamma-aminobutyric acid r ( 492) 1914 426.8 6.4e-119 NP_001273756 (OMIM: 103780,137140) gamma-aminobuty ( 456) 1810 404.1 3.9e-112 NP_001191195 (OMIM: 137141) gamma-aminobutyric aci ( 535) 1561 349.9 9.7e-96 NP_000800 (OMIM: 137141) gamma-aminobutyric acid r ( 554) 1561 349.9 1e-95 NP_000802 (OMIM: 137143) gamma-aminobutyric acid r ( 453) 1532 343.6 6.6e-94 XP_006724874 (OMIM: 305660) PREDICTED: gamma-amino ( 340) 1460 327.8 2.7e-89 XP_016877544 (OMIM: 137142) PREDICTED: gamma-amino ( 306) 1454 326.5 6e-89 XP_016877545 (OMIM: 137142) PREDICTED: gamma-amino ( 306) 1454 326.5 6e-89 NP_775807 (OMIM: 137166) gamma-aminobutyric acid r ( 465) 1224 276.5 1.1e-73 NP_000807 (OMIM: 137164,607681,611277) gamma-amino ( 467) 1210 273.4 8.8e-73 NP_944494 (OMIM: 137164,607681,611277) gamma-amino ( 475) 1201 271.5 3.5e-72 NP_150092 (OMIM: 600233) gamma-aminobutyric acid r ( 467) 1104 250.3 7.8e-66 XP_011519732 (OMIM: 600233) PREDICTED: gamma-amino ( 473) 1104 250.3 7.9e-66 XP_016863479 (OMIM: 137166) PREDICTED: gamma-amino ( 336) 987 224.8 2.7e-58 NP_000162 (OMIM: 138491,149400) glycine receptor s ( 449) 983 224.0 6.5e-58 XP_016864838 (OMIM: 138491,149400) PREDICTED: glyc ( 465) 983 224.0 6.7e-58 NP_001036008 (OMIM: 600421) glycine receptor subun ( 449) 974 222.0 2.5e-57 XP_011543797 (OMIM: 305990) PREDICTED: glycine rec ( 436) 973 221.8 2.8e-57 XP_011543798 (OMIM: 305990) PREDICTED: glycine rec ( 436) 973 221.8 2.8e-57 XP_006724550 (OMIM: 305990) PREDICTED: glycine rec ( 436) 973 221.8 2.8e-57 NP_001112357 (OMIM: 305990) glycine receptor subun ( 452) 973 221.8 2.9e-57 NP_002054 (OMIM: 305990) glycine receptor subunit ( 452) 973 221.8 2.9e-57 NP_001139512 (OMIM: 138491,149400) glycine recepto ( 457) 972 221.6 3.5e-57 NP_001112358 (OMIM: 305990) glycine receptor subun ( 452) 971 221.4 4e-57 XP_016884916 (OMIM: 305990) PREDICTED: glycine rec ( 452) 971 221.4 4e-57 NP_001191196 (OMIM: 137141) gamma-aminobutyric aci ( 484) 970 221.2 4.9e-57 NP_006520 (OMIM: 600421) glycine receptor subunit ( 464) 963 219.6 1.4e-56 NP_004952 (OMIM: 300093) gamma-aminobutyric acid r ( 506) 963 219.6 1.5e-56 XP_016864119 (OMIM: 600421) PREDICTED: glycine rec ( 424) 945 215.7 1.9e-55 NP_000803 (OMIM: 137190,617153) gamma-aminobutyric ( 474) 894 204.6 4.6e-52 NP_000804 (OMIM: 600232) gamma-aminobutyric acid r ( 474) 886 202.9 1.6e-51 NP_068711 (OMIM: 600232) gamma-aminobutyric acid r ( 512) 886 202.9 1.7e-51 XP_016877548 (OMIM: 600233) PREDICTED: gamma-amino ( 355) 881 201.7 2.5e-51 XP_016877547 (OMIM: 600233) PREDICTED: gamma-amino ( 361) 881 201.7 2.6e-51 >>XP_016863472 (OMIM: 103780,137140) PREDICTED: gamma-am (451 aa) initn: 2974 init1: 2974 opt: 2974 Z-score: 3504.3 bits: 657.6 E(85289): 1.9e-188 Smith-Waterman score: 2974; 100.0% identity (100.0% similar) in 451 aa overlap (1-451:1-451) 10 20 30 40 50 60 pF1KB4 MKTKLNIYNMQFLLFVFLVWDPARLVLANIQEDEAKNNITIFTRILDRLLDGYDNRLRPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MKTKLNIYNMQFLLFVFLVWDPARLVLANIQEDEAKNNITIFTRILDRLLDGYDNRLRPG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 LGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERLKFKGPMNILRLNNLMASK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERLKFKGPMNILRLNNLMASK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 IWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLTVQAECPMHLEDFPMDAHSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLTVQAECPMHLEDFPMDAHSC 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 PLKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLLGQSIGKETIKSSTGEYTVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PLKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLLGQSIGKETIKSSTGEYTVM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 TAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKSVVNDKKKEKASV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKSVVNDKKKEKASV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 MIQNNAYAVAVANYAPNLSKDPVLSTISKSATTPEPNKKPENKPAEAKKTFNSVSKIDRM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MIQNNAYAVAVANYAPNLSKDPVLSTISKSATTPEPNKKPENKPAEAKKTFNSVSKIDRM 370 380 390 400 410 420 430 440 450 pF1KB4 SRIVFPVLFGTFNLVYWATYLNREPVLGVSP ::::::::::::::::::::::::::::::: XP_016 SRIVFPVLFGTFNLVYWATYLNREPVLGVSP 430 440 450 >>NP_000798 (OMIM: 103780,137140) gamma-aminobutyric aci (451 aa) initn: 2974 init1: 2974 opt: 2974 Z-score: 3504.3 bits: 657.6 E(85289): 1.9e-188 Smith-Waterman score: 2974; 100.0% identity (100.0% similar) in 451 aa overlap (1-451:1-451) 10 20 30 40 50 60 pF1KB4 MKTKLNIYNMQFLLFVFLVWDPARLVLANIQEDEAKNNITIFTRILDRLLDGYDNRLRPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 MKTKLNIYNMQFLLFVFLVWDPARLVLANIQEDEAKNNITIFTRILDRLLDGYDNRLRPG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 LGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERLKFKGPMNILRLNNLMASK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 LGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERLKFKGPMNILRLNNLMASK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 IWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLTVQAECPMHLEDFPMDAHSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 IWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLTVQAECPMHLEDFPMDAHSC 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 PLKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLLGQSIGKETIKSSTGEYTVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 PLKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLLGQSIGKETIKSSTGEYTVM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 TAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 TAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKSVVNDKKKEKASV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKSVVNDKKKEKASV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 MIQNNAYAVAVANYAPNLSKDPVLSTISKSATTPEPNKKPENKPAEAKKTFNSVSKIDRM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 MIQNNAYAVAVANYAPNLSKDPVLSTISKSATTPEPNKKPENKPAEAKKTFNSVSKIDRM 370 380 390 400 410 420 430 440 450 pF1KB4 SRIVFPVLFGTFNLVYWATYLNREPVLGVSP ::::::::::::::::::::::::::::::: NP_000 SRIVFPVLFGTFNLVYWATYLNREPVLGVSP 430 440 450 >>NP_001107647 (OMIM: 103780,137140) gamma-aminobutyric (451 aa) initn: 2974 init1: 2974 opt: 2974 Z-score: 3504.3 bits: 657.6 E(85289): 1.9e-188 Smith-Waterman score: 2974; 100.0% identity (100.0% similar) in 451 aa overlap (1-451:1-451) 10 20 30 40 50 60 pF1KB4 MKTKLNIYNMQFLLFVFLVWDPARLVLANIQEDEAKNNITIFTRILDRLLDGYDNRLRPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MKTKLNIYNMQFLLFVFLVWDPARLVLANIQEDEAKNNITIFTRILDRLLDGYDNRLRPG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 LGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERLKFKGPMNILRLNNLMASK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERLKFKGPMNILRLNNLMASK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 IWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLTVQAECPMHLEDFPMDAHSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLTVQAECPMHLEDFPMDAHSC 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 PLKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLLGQSIGKETIKSSTGEYTVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PLKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLLGQSIGKETIKSSTGEYTVM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 TAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKSVVNDKKKEKASV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKSVVNDKKKEKASV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 MIQNNAYAVAVANYAPNLSKDPVLSTISKSATTPEPNKKPENKPAEAKKTFNSVSKIDRM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MIQNNAYAVAVANYAPNLSKDPVLSTISKSATTPEPNKKPENKPAEAKKTFNSVSKIDRM 370 380 390 400 410 420 430 440 450 pF1KB4 SRIVFPVLFGTFNLVYWATYLNREPVLGVSP ::::::::::::::::::::::::::::::: NP_001 SRIVFPVLFGTFNLVYWATYLNREPVLGVSP 430 440 450 >>XP_016863471 (OMIM: 103780,137140) PREDICTED: gamma-am (451 aa) initn: 2974 init1: 2974 opt: 2974 Z-score: 3504.3 bits: 657.6 E(85289): 1.9e-188 Smith-Waterman score: 2974; 100.0% identity (100.0% similar) in 451 aa overlap (1-451:1-451) 10 20 30 40 50 60 pF1KB4 MKTKLNIYNMQFLLFVFLVWDPARLVLANIQEDEAKNNITIFTRILDRLLDGYDNRLRPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MKTKLNIYNMQFLLFVFLVWDPARLVLANIQEDEAKNNITIFTRILDRLLDGYDNRLRPG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 LGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERLKFKGPMNILRLNNLMASK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERLKFKGPMNILRLNNLMASK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 IWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLTVQAECPMHLEDFPMDAHSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLTVQAECPMHLEDFPMDAHSC 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 PLKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLLGQSIGKETIKSSTGEYTVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PLKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLLGQSIGKETIKSSTGEYTVM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 TAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKSVVNDKKKEKASV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKSVVNDKKKEKASV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB4 MIQNNAYAVAVANYAPNLSKDPVLSTISKSATTPEPNKKPENKPAEAKKTFNSVSKIDRM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MIQNNAYAVAVANYAPNLSKDPVLSTISKSATTPEPNKKPENKPAEAKKTFNSVSKIDRM 370 380 390 400 410 420 430 440 450 pF1KB4 SRIVFPVLFGTFNLVYWATYLNREPVLGVSP ::::::::::::::::::::::::::::::: XP_016 SRIVFPVLFGTFNLVYWATYLNREPVLGVSP 430 440 450 >>XP_005248137 (OMIM: 103780,137140) PREDICTED: gamma-am (396 aa) initn: 2421 init1: 2421 opt: 2434 Z-score: 2869.6 bits: 540.0 E(85289): 4.3e-153 Smith-Waterman score: 2434; 93.9% identity (97.2% similar) in 396 aa overlap (56-451:2-396) 30 40 50 60 70 80 pF1KB4 VLANIQEDEAKNNITIFTRILDRLLDGYDNRLRPGLGDSITEVFTNIYVTSFGPVSDTDM ::. : :. : .:....... ... XP_005 MRLKITL-PSLREFLTDFWMVTIIGLDQDWE 10 20 30 90 100 110 120 130 140 pF1KB4 EYTIDVFFRQKWKDERLKFKGPMNILRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EYTIDVFFRQKWKDERLKFKGPMNILRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKL 40 50 60 70 80 90 150 160 170 180 190 200 pF1KB4 LRIQDDGTLLYTMRLTVQAECPMHLEDFPMDAHSCPLKFGSYAYTTSEVTYIWTYNASDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LRIQDDGTLLYTMRLTVQAECPMHLEDFPMDAHSCPLKFGSYAYTTSEVTYIWTYNASDS 100 110 120 130 140 150 210 220 230 240 250 260 pF1KB4 VQVAPDGSRLNQYDLLGQSIGKETIKSSTGEYTVMTAHFHLKRKIGYFVIQTYLPCIMTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VQVAPDGSRLNQYDLLGQSIGKETIKSSTGEYTVMTAHFHLKRKIGYFVIQTYLPCIMTV 160 170 180 190 200 210 270 280 290 300 310 320 pF1KB4 ILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVF 220 230 240 250 260 270 330 340 350 360 370 380 pF1KB4 SALIEFATVNYFTKRGWAWDGKSVVNDKKKEKASVMIQNNAYAVAVANYAPNLSKDPVLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SALIEFATVNYFTKRGWAWDGKSVVNDKKKEKASVMIQNNAYAVAVANYAPNLSKDPVLS 280 290 300 310 320 330 390 400 410 420 430 440 pF1KB4 TISKSATTPEPNKKPENKPAEAKKTFNSVSKIDRMSRIVFPVLFGTFNLVYWATYLNREP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TISKSATTPEPNKKPENKPAEAKKTFNSVSKIDRMSRIVFPVLFGTFNLVYWATYLNREP 340 350 360 370 380 390 450 pF1KB4 VLGVSP :::::: XP_005 VLGVSP >>NP_001317619 (OMIM: 103780,137140) gamma-aminobutyric (511 aa) initn: 2960 init1: 2347 opt: 2350 Z-score: 2768.9 bits: 521.7 E(85289): 1.7e-147 Smith-Waterman score: 2651; 87.6% identity (87.6% similar) in 483 aa overlap (1-423:1-483) 10 20 30 40 50 60 pF1KB4 MKTKLNIYNMQFLLFVFLVWDPARLVLANIQEDEAKNNITIFTRILDRLLDGYDNRLRPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MKTKLNIYNMQFLLFVFLVWDPARLVLANIQEDEAKNNITIFTRILDRLLDGYDNRLRPG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 LGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERLKFKGPMNILRLNNLMASK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERLKFKGPMNILRLNNLMASK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 IWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLTVQAECPMHLEDFPMDAHSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLTVQAECPMHLEDFPMDAHSC 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 PLKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLLGQSIGKETIKSSTGEYTVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PLKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLLGQSIGKETIKSSTGEYTVM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 TAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA 250 260 270 280 290 300 310 320 330 340 350 pF1KB4 RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKSVVNDK------- ::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKSVVNDKSPSIKAE 310 320 330 340 350 360 360 pF1KB4 -----------------------------------------------------KKEKASV ::::::: NP_001 GITLTYNSVKAILQGAKLIWSKYIAFSWPSLFQEKTLEYLEKWMDCLTFKQSSKKEKASV 370 380 390 400 410 420 370 380 390 400 410 420 pF1KB4 MIQNNAYAVAVANYAPNLSKDPVLSTISKSATTPEPNKKPENKPAEAKKTFNSVSKIDRM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MIQNNAYAVAVANYAPNLSKDPVLSTISKSATTPEPNKKPENKPAEAKKTFNSVSKIDRM 430 440 450 460 470 480 430 440 450 pF1KB4 SRIVFPVLFGTFNLVYWATYLNREPVLGVSP ::: NP_001 SRIVFPVLFGTFNLVYWATYLNREPVLGVSP 490 500 510 >>XP_011511977 (OMIM: 103780,137140) PREDICTED: gamma-am (511 aa) initn: 2960 init1: 2347 opt: 2350 Z-score: 2768.9 bits: 521.7 E(85289): 1.7e-147 Smith-Waterman score: 2651; 87.6% identity (87.6% similar) in 483 aa overlap (1-423:1-483) 10 20 30 40 50 60 pF1KB4 MKTKLNIYNMQFLLFVFLVWDPARLVLANIQEDEAKNNITIFTRILDRLLDGYDNRLRPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MKTKLNIYNMQFLLFVFLVWDPARLVLANIQEDEAKNNITIFTRILDRLLDGYDNRLRPG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 LGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERLKFKGPMNILRLNNLMASK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERLKFKGPMNILRLNNLMASK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 IWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLTVQAECPMHLEDFPMDAHSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLTVQAECPMHLEDFPMDAHSC 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 PLKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLLGQSIGKETIKSSTGEYTVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PLKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLLGQSIGKETIKSSTGEYTVM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 TAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA 250 260 270 280 290 300 310 320 330 340 350 pF1KB4 RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKSVVNDK------- ::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKSVVNDKSPSIKAE 310 320 330 340 350 360 360 pF1KB4 -----------------------------------------------------KKEKASV ::::::: XP_011 GITLTYNSVKAILQGAKLIWSKYIAFSWPSLFQEKTLEYLEKWMDCLTFKQSSKKEKASV 370 380 390 400 410 420 370 380 390 400 410 420 pF1KB4 MIQNNAYAVAVANYAPNLSKDPVLSTISKSATTPEPNKKPENKPAEAKKTFNSVSKIDRM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MIQNNAYAVAVANYAPNLSKDPVLSTISKSATTPEPNKKPENKPAEAKKTFNSVSKIDRM 430 440 450 460 470 480 430 440 450 pF1KB4 SRIVFPVLFGTFNLVYWATYLNREPVLGVSP ::: XP_011 SRIVFPVLFGTFNLVYWATYLNREPVLGVSP 490 500 510 >>NP_001121115 (OMIM: 137160,611136,615744) gamma-aminob (456 aa) initn: 2258 init1: 1888 opt: 2255 Z-score: 2657.9 bits: 501.0 E(85289): 2.6e-141 Smith-Waterman score: 2255; 81.3% identity (91.9% similar) in 418 aa overlap (32-447:32-449) 10 20 30 40 50 60 pF1KB4 KTKLNIYNMQFLLFVFLVWDPARLVLANIQEDEAKNNITIFTRILDRLLDGYDNRLRPGL .:: :.: :.:::::::::::::::::::: NP_001 RKSPGLSDCLWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPGL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 GDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERLKFKGPMNILRLNNLMASKI :. .::: :.:.::::::::: ::::::::::::.::::::::::::..::::::::::: NP_001 GERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASKI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 WTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLTVQAECPMHLEDFPMDAHSCP ::::::::::::::::::::::::::: .::::::::::::.:::::::::::::::.:: NP_001 WTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHACP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 LKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLLGQSIGKETIKSSTGEYTVMT ::::::::: .::.: :: . . :: :: :::::::::::::.. . ..::::::.::: NP_001 LKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVMT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 AHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISAR .::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 THFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISAR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 NSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKSVVNDK-KKEKASV ::::::::::::::::::::::::::::::::::::::::.:::::::: .: :: : . NP_001 NSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEKPKKVKDPL 310 320 330 340 350 360 370 380 390 400 410 pF1KB4 MIQNNAYAVAVANYAPNLSK-DPVLSTISKSATTPEPNKKPENKPAEAKKTFNSVSKIDR . .::.:: ....:.:::.. :: :.::.:::: . :::.:: : :::::::::::: NP_001 IKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKEVKPETKPPEPKKTFNSVSKIDR 370 380 390 400 410 420 420 430 440 450 pF1KB4 MSRIVFPVLFGTFNLVYWATYLNREPVLGVSP .:::.::.::: :::::::::::::: : NP_001 LSRIAFPLLFGIFNLVYWATYLNREPQLKAPTPHQ 430 440 450 >>NP_000797 (OMIM: 137160,611136,615744) gamma-aminobuty (456 aa) initn: 2258 init1: 1888 opt: 2255 Z-score: 2657.9 bits: 501.0 E(85289): 2.6e-141 Smith-Waterman score: 2255; 81.3% identity (91.9% similar) in 418 aa overlap (32-447:32-449) 10 20 30 40 50 60 pF1KB4 KTKLNIYNMQFLLFVFLVWDPARLVLANIQEDEAKNNITIFTRILDRLLDGYDNRLRPGL .:: :.: :.:::::::::::::::::::: NP_000 RKSPGLSDCLWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPGL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 GDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERLKFKGPMNILRLNNLMASKI :. .::: :.:.::::::::: ::::::::::::.::::::::::::..::::::::::: NP_000 GERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASKI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 WTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLTVQAECPMHLEDFPMDAHSCP ::::::::::::::::::::::::::: .::::::::::::.:::::::::::::::.:: NP_000 WTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHACP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 LKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLLGQSIGKETIKSSTGEYTVMT ::::::::: .::.: :: . . :: :: :::::::::::::.. . ..::::::.::: NP_000 LKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVMT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 AHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISAR .::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 THFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISAR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 NSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKSVVNDK-KKEKASV ::::::::::::::::::::::::::::::::::::::::.:::::::: .: :: : . NP_000 NSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEKPKKVKDPL 310 320 330 340 350 360 370 380 390 400 410 pF1KB4 MIQNNAYAVAVANYAPNLSK-DPVLSTISKSATTPEPNKKPENKPAEAKKTFNSVSKIDR . .::.:: ....:.:::.. :: :.::.:::: . :::.:: : :::::::::::: NP_000 IKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKEVKPETKPPEPKKTFNSVSKIDR 370 380 390 400 410 420 420 430 440 450 pF1KB4 MSRIVFPVLFGTFNLVYWATYLNREPVLGVSP .:::.::.::: :::::::::::::: : NP_000 LSRIAFPLLFGIFNLVYWATYLNREPQLKAPTPHQ 430 440 450 >>NP_001121120 (OMIM: 137160,611136,615744) gamma-aminob (456 aa) initn: 2258 init1: 1888 opt: 2255 Z-score: 2657.9 bits: 501.0 E(85289): 2.6e-141 Smith-Waterman score: 2255; 81.3% identity (91.9% similar) in 418 aa overlap (32-447:32-449) 10 20 30 40 50 60 pF1KB4 KTKLNIYNMQFLLFVFLVWDPARLVLANIQEDEAKNNITIFTRILDRLLDGYDNRLRPGL .:: :.: :.:::::::::::::::::::: NP_001 RKSPGLSDCLWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPGL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 GDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERLKFKGPMNILRLNNLMASKI :. .::: :.:.::::::::: ::::::::::::.::::::::::::..::::::::::: NP_001 GERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASKI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 WTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLTVQAECPMHLEDFPMDAHSCP ::::::::::::::::::::::::::: .::::::::::::.:::::::::::::::.:: NP_001 WTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHACP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 LKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLLGQSIGKETIKSSTGEYTVMT ::::::::: .::.: :: . . :: :: :::::::::::::.. . ..::::::.::: NP_001 LKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVMT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 AHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISAR .::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 THFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISAR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB4 NSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKSVVNDK-KKEKASV ::::::::::::::::::::::::::::::::::::::::.:::::::: .: :: : . NP_001 NSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEKPKKVKDPL 310 320 330 340 350 360 370 380 390 400 410 pF1KB4 MIQNNAYAVAVANYAPNLSK-DPVLSTISKSATTPEPNKKPENKPAEAKKTFNSVSKIDR . .::.:: ....:.:::.. :: :.::.:::: . :::.:: : :::::::::::: NP_001 IKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKEVKPETKPPEPKKTFNSVSKIDR 370 380 390 400 410 420 420 430 440 450 pF1KB4 MSRIVFPVLFGTFNLVYWATYLNREPVLGVSP .:::.::.::: :::::::::::::: : NP_001 LSRIAFPLLFGIFNLVYWATYLNREPQLKAPTPHQ 430 440 450 451 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 14:35:08 2016 done: Thu Nov 3 14:35:09 2016 Total Scan time: 8.370 Total Display time: 0.080 Function used was FASTA [36.3.4 Apr, 2011]