Result of FASTA (omim) for pF1KB4176
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB4176, 451 aa
  1>>>pF1KB4176 451 - 451 aa - 451 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.0548+/-0.000457; mu= 13.1897+/- 0.029
 mean_var=72.1776+/-14.411, 0's: 0 Z-trim(108.5): 168  B-trim: 0 in 0/59
 Lambda= 0.150964
 statistics sampled from 16424 (16605) to 16424 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.543), E-opt: 0.2 (0.195), width:  16
 Scan time:  8.370

The best scores are:                                      opt bits E(85289)
XP_016863472 (OMIM: 103780,137140) PREDICTED: gamm ( 451) 2974 657.6 1.9e-188
NP_000798 (OMIM: 103780,137140) gamma-aminobutyric ( 451) 2974 657.6 1.9e-188
NP_001107647 (OMIM: 103780,137140) gamma-aminobuty ( 451) 2974 657.6 1.9e-188
XP_016863471 (OMIM: 103780,137140) PREDICTED: gamm ( 451) 2974 657.6 1.9e-188
XP_005248137 (OMIM: 103780,137140) PREDICTED: gamm ( 396) 2434 540.0 4.3e-153
NP_001317619 (OMIM: 103780,137140) gamma-aminobuty ( 511) 2350 521.7 1.7e-147
XP_011511977 (OMIM: 103780,137140) PREDICTED: gamm ( 511) 2350 521.7 1.7e-147
NP_001121115 (OMIM: 137160,611136,615744) gamma-am ( 456) 2255 501.0 2.6e-141
NP_000797 (OMIM: 137160,611136,615744) gamma-amino ( 456) 2255 501.0 2.6e-141
NP_001121120 (OMIM: 137160,611136,615744) gamma-am ( 456) 2255 501.0 2.6e-141
NP_001121117 (OMIM: 137160,611136,615744) gamma-am ( 456) 2255 501.0 2.6e-141
NP_001121116 (OMIM: 137160,611136,615744) gamma-am ( 456) 2255 501.0 2.6e-141
NP_000801 (OMIM: 137142) gamma-aminobutyric acid r ( 462) 2156 479.5 8.3e-135
NP_001158509 (OMIM: 137142) gamma-aminobutyric aci ( 462) 2156 479.5 8.3e-135
XP_005268315 (OMIM: 137142) PREDICTED: gamma-amino ( 462) 2156 479.5 8.3e-135
XP_006720522 (OMIM: 137142) PREDICTED: gamma-amino ( 462) 2156 479.5 8.3e-135
NP_000799 (OMIM: 305660) gamma-aminobutyric acid r ( 492) 1914 426.8 6.4e-119
NP_001273756 (OMIM: 103780,137140) gamma-aminobuty ( 456) 1810 404.1 3.9e-112
NP_001191195 (OMIM: 137141) gamma-aminobutyric aci ( 535) 1561 349.9 9.7e-96
NP_000800 (OMIM: 137141) gamma-aminobutyric acid r ( 554) 1561 349.9   1e-95
NP_000802 (OMIM: 137143) gamma-aminobutyric acid r ( 453) 1532 343.6 6.6e-94
XP_006724874 (OMIM: 305660) PREDICTED: gamma-amino ( 340) 1460 327.8 2.7e-89
XP_016877544 (OMIM: 137142) PREDICTED: gamma-amino ( 306) 1454 326.5   6e-89
XP_016877545 (OMIM: 137142) PREDICTED: gamma-amino ( 306) 1454 326.5   6e-89
NP_775807 (OMIM: 137166) gamma-aminobutyric acid r ( 465) 1224 276.5 1.1e-73
NP_000807 (OMIM: 137164,607681,611277) gamma-amino ( 467) 1210 273.4 8.8e-73
NP_944494 (OMIM: 137164,607681,611277) gamma-amino ( 475) 1201 271.5 3.5e-72
NP_150092 (OMIM: 600233) gamma-aminobutyric acid r ( 467) 1104 250.3 7.8e-66
XP_011519732 (OMIM: 600233) PREDICTED: gamma-amino ( 473) 1104 250.3 7.9e-66
XP_016863479 (OMIM: 137166) PREDICTED: gamma-amino ( 336)  987 224.8 2.7e-58
NP_000162 (OMIM: 138491,149400) glycine receptor s ( 449)  983 224.0 6.5e-58
XP_016864838 (OMIM: 138491,149400) PREDICTED: glyc ( 465)  983 224.0 6.7e-58
NP_001036008 (OMIM: 600421) glycine receptor subun ( 449)  974 222.0 2.5e-57
XP_011543797 (OMIM: 305990) PREDICTED: glycine rec ( 436)  973 221.8 2.8e-57
XP_011543798 (OMIM: 305990) PREDICTED: glycine rec ( 436)  973 221.8 2.8e-57
XP_006724550 (OMIM: 305990) PREDICTED: glycine rec ( 436)  973 221.8 2.8e-57
NP_001112357 (OMIM: 305990) glycine receptor subun ( 452)  973 221.8 2.9e-57
NP_002054 (OMIM: 305990) glycine receptor subunit  ( 452)  973 221.8 2.9e-57
NP_001139512 (OMIM: 138491,149400) glycine recepto ( 457)  972 221.6 3.5e-57
NP_001112358 (OMIM: 305990) glycine receptor subun ( 452)  971 221.4   4e-57
XP_016884916 (OMIM: 305990) PREDICTED: glycine rec ( 452)  971 221.4   4e-57
NP_001191196 (OMIM: 137141) gamma-aminobutyric aci ( 484)  970 221.2 4.9e-57
NP_006520 (OMIM: 600421) glycine receptor subunit  ( 464)  963 219.6 1.4e-56
NP_004952 (OMIM: 300093) gamma-aminobutyric acid r ( 506)  963 219.6 1.5e-56
XP_016864119 (OMIM: 600421) PREDICTED: glycine rec ( 424)  945 215.7 1.9e-55
NP_000803 (OMIM: 137190,617153) gamma-aminobutyric ( 474)  894 204.6 4.6e-52
NP_000804 (OMIM: 600232) gamma-aminobutyric acid r ( 474)  886 202.9 1.6e-51
NP_068711 (OMIM: 600232) gamma-aminobutyric acid r ( 512)  886 202.9 1.7e-51
XP_016877548 (OMIM: 600233) PREDICTED: gamma-amino ( 355)  881 201.7 2.5e-51
XP_016877547 (OMIM: 600233) PREDICTED: gamma-amino ( 361)  881 201.7 2.6e-51


>>XP_016863472 (OMIM: 103780,137140) PREDICTED: gamma-am  (451 aa)
 initn: 2974 init1: 2974 opt: 2974  Z-score: 3504.3  bits: 657.6 E(85289): 1.9e-188
Smith-Waterman score: 2974; 100.0% identity (100.0% similar) in 451 aa overlap (1-451:1-451)

               10        20        30        40        50        60
pF1KB4 MKTKLNIYNMQFLLFVFLVWDPARLVLANIQEDEAKNNITIFTRILDRLLDGYDNRLRPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKTKLNIYNMQFLLFVFLVWDPARLVLANIQEDEAKNNITIFTRILDRLLDGYDNRLRPG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB4 LGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERLKFKGPMNILRLNNLMASK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERLKFKGPMNILRLNNLMASK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB4 IWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLTVQAECPMHLEDFPMDAHSC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLTVQAECPMHLEDFPMDAHSC
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB4 PLKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLLGQSIGKETIKSSTGEYTVM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLLGQSIGKETIKSSTGEYTVM
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB4 TAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB4 RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKSVVNDKKKEKASV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKSVVNDKKKEKASV
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB4 MIQNNAYAVAVANYAPNLSKDPVLSTISKSATTPEPNKKPENKPAEAKKTFNSVSKIDRM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MIQNNAYAVAVANYAPNLSKDPVLSTISKSATTPEPNKKPENKPAEAKKTFNSVSKIDRM
              370       380       390       400       410       420

              430       440       450 
pF1KB4 SRIVFPVLFGTFNLVYWATYLNREPVLGVSP
       :::::::::::::::::::::::::::::::
XP_016 SRIVFPVLFGTFNLVYWATYLNREPVLGVSP
              430       440       450 

>>NP_000798 (OMIM: 103780,137140) gamma-aminobutyric aci  (451 aa)
 initn: 2974 init1: 2974 opt: 2974  Z-score: 3504.3  bits: 657.6 E(85289): 1.9e-188
Smith-Waterman score: 2974; 100.0% identity (100.0% similar) in 451 aa overlap (1-451:1-451)

               10        20        30        40        50        60
pF1KB4 MKTKLNIYNMQFLLFVFLVWDPARLVLANIQEDEAKNNITIFTRILDRLLDGYDNRLRPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MKTKLNIYNMQFLLFVFLVWDPARLVLANIQEDEAKNNITIFTRILDRLLDGYDNRLRPG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB4 LGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERLKFKGPMNILRLNNLMASK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERLKFKGPMNILRLNNLMASK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB4 IWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLTVQAECPMHLEDFPMDAHSC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 IWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLTVQAECPMHLEDFPMDAHSC
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB4 PLKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLLGQSIGKETIKSSTGEYTVM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PLKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLLGQSIGKETIKSSTGEYTVM
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB4 TAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB4 RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKSVVNDKKKEKASV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKSVVNDKKKEKASV
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB4 MIQNNAYAVAVANYAPNLSKDPVLSTISKSATTPEPNKKPENKPAEAKKTFNSVSKIDRM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MIQNNAYAVAVANYAPNLSKDPVLSTISKSATTPEPNKKPENKPAEAKKTFNSVSKIDRM
              370       380       390       400       410       420

              430       440       450 
pF1KB4 SRIVFPVLFGTFNLVYWATYLNREPVLGVSP
       :::::::::::::::::::::::::::::::
NP_000 SRIVFPVLFGTFNLVYWATYLNREPVLGVSP
              430       440       450 

>>NP_001107647 (OMIM: 103780,137140) gamma-aminobutyric   (451 aa)
 initn: 2974 init1: 2974 opt: 2974  Z-score: 3504.3  bits: 657.6 E(85289): 1.9e-188
Smith-Waterman score: 2974; 100.0% identity (100.0% similar) in 451 aa overlap (1-451:1-451)

               10        20        30        40        50        60
pF1KB4 MKTKLNIYNMQFLLFVFLVWDPARLVLANIQEDEAKNNITIFTRILDRLLDGYDNRLRPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKTKLNIYNMQFLLFVFLVWDPARLVLANIQEDEAKNNITIFTRILDRLLDGYDNRLRPG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB4 LGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERLKFKGPMNILRLNNLMASK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERLKFKGPMNILRLNNLMASK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB4 IWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLTVQAECPMHLEDFPMDAHSC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLTVQAECPMHLEDFPMDAHSC
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB4 PLKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLLGQSIGKETIKSSTGEYTVM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PLKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLLGQSIGKETIKSSTGEYTVM
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB4 TAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB4 RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKSVVNDKKKEKASV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKSVVNDKKKEKASV
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB4 MIQNNAYAVAVANYAPNLSKDPVLSTISKSATTPEPNKKPENKPAEAKKTFNSVSKIDRM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MIQNNAYAVAVANYAPNLSKDPVLSTISKSATTPEPNKKPENKPAEAKKTFNSVSKIDRM
              370       380       390       400       410       420

              430       440       450 
pF1KB4 SRIVFPVLFGTFNLVYWATYLNREPVLGVSP
       :::::::::::::::::::::::::::::::
NP_001 SRIVFPVLFGTFNLVYWATYLNREPVLGVSP
              430       440       450 

>>XP_016863471 (OMIM: 103780,137140) PREDICTED: gamma-am  (451 aa)
 initn: 2974 init1: 2974 opt: 2974  Z-score: 3504.3  bits: 657.6 E(85289): 1.9e-188
Smith-Waterman score: 2974; 100.0% identity (100.0% similar) in 451 aa overlap (1-451:1-451)

               10        20        30        40        50        60
pF1KB4 MKTKLNIYNMQFLLFVFLVWDPARLVLANIQEDEAKNNITIFTRILDRLLDGYDNRLRPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKTKLNIYNMQFLLFVFLVWDPARLVLANIQEDEAKNNITIFTRILDRLLDGYDNRLRPG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB4 LGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERLKFKGPMNILRLNNLMASK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERLKFKGPMNILRLNNLMASK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB4 IWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLTVQAECPMHLEDFPMDAHSC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLTVQAECPMHLEDFPMDAHSC
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB4 PLKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLLGQSIGKETIKSSTGEYTVM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLLGQSIGKETIKSSTGEYTVM
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB4 TAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB4 RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKSVVNDKKKEKASV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKSVVNDKKKEKASV
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB4 MIQNNAYAVAVANYAPNLSKDPVLSTISKSATTPEPNKKPENKPAEAKKTFNSVSKIDRM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MIQNNAYAVAVANYAPNLSKDPVLSTISKSATTPEPNKKPENKPAEAKKTFNSVSKIDRM
              370       380       390       400       410       420

              430       440       450 
pF1KB4 SRIVFPVLFGTFNLVYWATYLNREPVLGVSP
       :::::::::::::::::::::::::::::::
XP_016 SRIVFPVLFGTFNLVYWATYLNREPVLGVSP
              430       440       450 

>>XP_005248137 (OMIM: 103780,137140) PREDICTED: gamma-am  (396 aa)
 initn: 2421 init1: 2421 opt: 2434  Z-score: 2869.6  bits: 540.0 E(85289): 4.3e-153
Smith-Waterman score: 2434; 93.9% identity (97.2% similar) in 396 aa overlap (56-451:2-396)

          30        40        50        60        70        80     
pF1KB4 VLANIQEDEAKNNITIFTRILDRLLDGYDNRLRPGLGDSITEVFTNIYVTSFGPVSDTDM
                                     ::.  :  :. : .:.......  ...   
XP_005                              MRLKITL-PSLREFLTDFWMVTIIGLDQDWE
                                             10        20        30

          90       100       110       120       130       140     
pF1KB4 EYTIDVFFRQKWKDERLKFKGPMNILRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EYTIDVFFRQKWKDERLKFKGPMNILRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKL
               40        50        60        70        80        90

         150       160       170       180       190       200     
pF1KB4 LRIQDDGTLLYTMRLTVQAECPMHLEDFPMDAHSCPLKFGSYAYTTSEVTYIWTYNASDS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LRIQDDGTLLYTMRLTVQAECPMHLEDFPMDAHSCPLKFGSYAYTTSEVTYIWTYNASDS
              100       110       120       130       140       150

         210       220       230       240       250       260     
pF1KB4 VQVAPDGSRLNQYDLLGQSIGKETIKSSTGEYTVMTAHFHLKRKIGYFVIQTYLPCIMTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VQVAPDGSRLNQYDLLGQSIGKETIKSSTGEYTVMTAHFHLKRKIGYFVIQTYLPCIMTV
              160       170       180       190       200       210

         270       280       290       300       310       320     
pF1KB4 ILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVF
              220       230       240       250       260       270

         330       340       350       360       370       380     
pF1KB4 SALIEFATVNYFTKRGWAWDGKSVVNDKKKEKASVMIQNNAYAVAVANYAPNLSKDPVLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SALIEFATVNYFTKRGWAWDGKSVVNDKKKEKASVMIQNNAYAVAVANYAPNLSKDPVLS
              280       290       300       310       320       330

         390       400       410       420       430       440     
pF1KB4 TISKSATTPEPNKKPENKPAEAKKTFNSVSKIDRMSRIVFPVLFGTFNLVYWATYLNREP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TISKSATTPEPNKKPENKPAEAKKTFNSVSKIDRMSRIVFPVLFGTFNLVYWATYLNREP
              340       350       360       370       380       390

         450 
pF1KB4 VLGVSP
       ::::::
XP_005 VLGVSP
             

>>NP_001317619 (OMIM: 103780,137140) gamma-aminobutyric   (511 aa)
 initn: 2960 init1: 2347 opt: 2350  Z-score: 2768.9  bits: 521.7 E(85289): 1.7e-147
Smith-Waterman score: 2651; 87.6% identity (87.6% similar) in 483 aa overlap (1-423:1-483)

               10        20        30        40        50        60
pF1KB4 MKTKLNIYNMQFLLFVFLVWDPARLVLANIQEDEAKNNITIFTRILDRLLDGYDNRLRPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKTKLNIYNMQFLLFVFLVWDPARLVLANIQEDEAKNNITIFTRILDRLLDGYDNRLRPG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB4 LGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERLKFKGPMNILRLNNLMASK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERLKFKGPMNILRLNNLMASK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB4 IWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLTVQAECPMHLEDFPMDAHSC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLTVQAECPMHLEDFPMDAHSC
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB4 PLKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLLGQSIGKETIKSSTGEYTVM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PLKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLLGQSIGKETIKSSTGEYTVM
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB4 TAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA
              250       260       270       280       290       300

              310       320       330       340       350          
pF1KB4 RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKSVVNDK-------
       :::::::::::::::::::::::::::::::::::::::::::::::::::::       
NP_001 RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKSVVNDKSPSIKAE
              310       320       330       340       350       360

                                                                360
pF1KB4 -----------------------------------------------------KKEKASV
                                                            :::::::
NP_001 GITLTYNSVKAILQGAKLIWSKYIAFSWPSLFQEKTLEYLEKWMDCLTFKQSSKKEKASV
              370       380       390       400       410       420

              370       380       390       400       410       420
pF1KB4 MIQNNAYAVAVANYAPNLSKDPVLSTISKSATTPEPNKKPENKPAEAKKTFNSVSKIDRM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MIQNNAYAVAVANYAPNLSKDPVLSTISKSATTPEPNKKPENKPAEAKKTFNSVSKIDRM
              430       440       450       460       470       480

              430       440       450 
pF1KB4 SRIVFPVLFGTFNLVYWATYLNREPVLGVSP
       :::                            
NP_001 SRIVFPVLFGTFNLVYWATYLNREPVLGVSP
              490       500       510 

>>XP_011511977 (OMIM: 103780,137140) PREDICTED: gamma-am  (511 aa)
 initn: 2960 init1: 2347 opt: 2350  Z-score: 2768.9  bits: 521.7 E(85289): 1.7e-147
Smith-Waterman score: 2651; 87.6% identity (87.6% similar) in 483 aa overlap (1-423:1-483)

               10        20        30        40        50        60
pF1KB4 MKTKLNIYNMQFLLFVFLVWDPARLVLANIQEDEAKNNITIFTRILDRLLDGYDNRLRPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MKTKLNIYNMQFLLFVFLVWDPARLVLANIQEDEAKNNITIFTRILDRLLDGYDNRLRPG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB4 LGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERLKFKGPMNILRLNNLMASK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERLKFKGPMNILRLNNLMASK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB4 IWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLTVQAECPMHLEDFPMDAHSC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLTVQAECPMHLEDFPMDAHSC
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB4 PLKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLLGQSIGKETIKSSTGEYTVM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLLGQSIGKETIKSSTGEYTVM
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB4 TAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISA
              250       260       270       280       290       300

              310       320       330       340       350          
pF1KB4 RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKSVVNDK-------
       :::::::::::::::::::::::::::::::::::::::::::::::::::::       
XP_011 RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKSVVNDKSPSIKAE
              310       320       330       340       350       360

                                                                360
pF1KB4 -----------------------------------------------------KKEKASV
                                                            :::::::
XP_011 GITLTYNSVKAILQGAKLIWSKYIAFSWPSLFQEKTLEYLEKWMDCLTFKQSSKKEKASV
              370       380       390       400       410       420

              370       380       390       400       410       420
pF1KB4 MIQNNAYAVAVANYAPNLSKDPVLSTISKSATTPEPNKKPENKPAEAKKTFNSVSKIDRM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MIQNNAYAVAVANYAPNLSKDPVLSTISKSATTPEPNKKPENKPAEAKKTFNSVSKIDRM
              430       440       450       460       470       480

              430       440       450 
pF1KB4 SRIVFPVLFGTFNLVYWATYLNREPVLGVSP
       :::                            
XP_011 SRIVFPVLFGTFNLVYWATYLNREPVLGVSP
              490       500       510 

>>NP_001121115 (OMIM: 137160,611136,615744) gamma-aminob  (456 aa)
 initn: 2258 init1: 1888 opt: 2255  Z-score: 2657.9  bits: 501.0 E(85289): 2.6e-141
Smith-Waterman score: 2255; 81.3% identity (91.9% similar) in 418 aa overlap (32-447:32-449)

              10        20        30        40        50        60 
pF1KB4 KTKLNIYNMQFLLFVFLVWDPARLVLANIQEDEAKNNITIFTRILDRLLDGYDNRLRPGL
                                     .:: :.: :.::::::::::::::::::::
NP_001 RKSPGLSDCLWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPGL
              10        20        30        40        50        60 

              70        80        90       100       110       120 
pF1KB4 GDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERLKFKGPMNILRLNNLMASKI
       :. .::: :.:.::::::::: ::::::::::::.::::::::::::..:::::::::::
NP_001 GERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASKI
              70        80        90       100       110       120 

             130       140       150       160       170       180 
pF1KB4 WTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLTVQAECPMHLEDFPMDAHSCP
       ::::::::::::::::::::::::::: .::::::::::::.:::::::::::::::.::
NP_001 WTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHACP
             130       140       150       160       170       180 

             190       200       210       220       230       240 
pF1KB4 LKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLLGQSIGKETIKSSTGEYTVMT
       ::::::::: .::.: :: . . :: :: :::::::::::::.. .  ..::::::.:::
NP_001 LKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVMT
             190       200       210       220       230       240 

             250       260       270       280       290       300 
pF1KB4 AHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISAR
       .:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 THFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISAR
             250       260       270       280       290       300 

             310       320       330       340       350        360
pF1KB4 NSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKSVVNDK-KKEKASV
       ::::::::::::::::::::::::::::::::::::::::.:::::::: .: :: :  .
NP_001 NSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEKPKKVKDPL
             310       320       330       340       350       360 

              370       380        390       400       410         
pF1KB4 MIQNNAYAVAVANYAPNLSK-DPVLSTISKSATTPEPNKKPENKPAEAKKTFNSVSKIDR
       . .::.:: ....:.:::.. :: :.::.::::    . :::.:: : ::::::::::::
NP_001 IKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKEVKPETKPPEPKKTFNSVSKIDR
             370       380       390       400       410       420 

     420       430       440       450    
pF1KB4 MSRIVFPVLFGTFNLVYWATYLNREPVLGVSP   
       .:::.::.::: :::::::::::::: :       
NP_001 LSRIAFPLLFGIFNLVYWATYLNREPQLKAPTPHQ
             430       440       450      

>>NP_000797 (OMIM: 137160,611136,615744) gamma-aminobuty  (456 aa)
 initn: 2258 init1: 1888 opt: 2255  Z-score: 2657.9  bits: 501.0 E(85289): 2.6e-141
Smith-Waterman score: 2255; 81.3% identity (91.9% similar) in 418 aa overlap (32-447:32-449)

              10        20        30        40        50        60 
pF1KB4 KTKLNIYNMQFLLFVFLVWDPARLVLANIQEDEAKNNITIFTRILDRLLDGYDNRLRPGL
                                     .:: :.: :.::::::::::::::::::::
NP_000 RKSPGLSDCLWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPGL
              10        20        30        40        50        60 

              70        80        90       100       110       120 
pF1KB4 GDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERLKFKGPMNILRLNNLMASKI
       :. .::: :.:.::::::::: ::::::::::::.::::::::::::..:::::::::::
NP_000 GERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASKI
              70        80        90       100       110       120 

             130       140       150       160       170       180 
pF1KB4 WTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLTVQAECPMHLEDFPMDAHSCP
       ::::::::::::::::::::::::::: .::::::::::::.:::::::::::::::.::
NP_000 WTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHACP
             130       140       150       160       170       180 

             190       200       210       220       230       240 
pF1KB4 LKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLLGQSIGKETIKSSTGEYTVMT
       ::::::::: .::.: :: . . :: :: :::::::::::::.. .  ..::::::.:::
NP_000 LKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVMT
             190       200       210       220       230       240 

             250       260       270       280       290       300 
pF1KB4 AHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISAR
       .:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 THFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISAR
             250       260       270       280       290       300 

             310       320       330       340       350        360
pF1KB4 NSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKSVVNDK-KKEKASV
       ::::::::::::::::::::::::::::::::::::::::.:::::::: .: :: :  .
NP_000 NSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEKPKKVKDPL
             310       320       330       340       350       360 

              370       380        390       400       410         
pF1KB4 MIQNNAYAVAVANYAPNLSK-DPVLSTISKSATTPEPNKKPENKPAEAKKTFNSVSKIDR
       . .::.:: ....:.:::.. :: :.::.::::    . :::.:: : ::::::::::::
NP_000 IKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKEVKPETKPPEPKKTFNSVSKIDR
             370       380       390       400       410       420 

     420       430       440       450    
pF1KB4 MSRIVFPVLFGTFNLVYWATYLNREPVLGVSP   
       .:::.::.::: :::::::::::::: :       
NP_000 LSRIAFPLLFGIFNLVYWATYLNREPQLKAPTPHQ
             430       440       450      

>>NP_001121120 (OMIM: 137160,611136,615744) gamma-aminob  (456 aa)
 initn: 2258 init1: 1888 opt: 2255  Z-score: 2657.9  bits: 501.0 E(85289): 2.6e-141
Smith-Waterman score: 2255; 81.3% identity (91.9% similar) in 418 aa overlap (32-447:32-449)

              10        20        30        40        50        60 
pF1KB4 KTKLNIYNMQFLLFVFLVWDPARLVLANIQEDEAKNNITIFTRILDRLLDGYDNRLRPGL
                                     .:: :.: :.::::::::::::::::::::
NP_001 RKSPGLSDCLWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPGL
              10        20        30        40        50        60 

              70        80        90       100       110       120 
pF1KB4 GDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERLKFKGPMNILRLNNLMASKI
       :. .::: :.:.::::::::: ::::::::::::.::::::::::::..:::::::::::
NP_001 GERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASKI
              70        80        90       100       110       120 

             130       140       150       160       170       180 
pF1KB4 WTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLTVQAECPMHLEDFPMDAHSCP
       ::::::::::::::::::::::::::: .::::::::::::.:::::::::::::::.::
NP_001 WTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHACP
             130       140       150       160       170       180 

             190       200       210       220       230       240 
pF1KB4 LKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLLGQSIGKETIKSSTGEYTVMT
       ::::::::: .::.: :: . . :: :: :::::::::::::.. .  ..::::::.:::
NP_001 LKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVMT
             190       200       210       220       230       240 

             250       260       270       280       290       300 
pF1KB4 AHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISAR
       .:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 THFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISAR
             250       260       270       280       290       300 

             310       320       330       340       350        360
pF1KB4 NSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKSVVNDK-KKEKASV
       ::::::::::::::::::::::::::::::::::::::::.:::::::: .: :: :  .
NP_001 NSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEKPKKVKDPL
             310       320       330       340       350       360 

              370       380        390       400       410         
pF1KB4 MIQNNAYAVAVANYAPNLSK-DPVLSTISKSATTPEPNKKPENKPAEAKKTFNSVSKIDR
       . .::.:: ....:.:::.. :: :.::.::::    . :::.:: : ::::::::::::
NP_001 IKKNNTYAPTATSYTPNLARGDPGLATIAKSATIEPKEVKPETKPPEPKKTFNSVSKIDR
             370       380       390       400       410       420 

     420       430       440       450    
pF1KB4 MSRIVFPVLFGTFNLVYWATYLNREPVLGVSP   
       .:::.::.::: :::::::::::::: :       
NP_001 LSRIAFPLLFGIFNLVYWATYLNREPQLKAPTPHQ
             430       440       450      




451 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 14:35:08 2016 done: Thu Nov  3 14:35:09 2016
 Total Scan time:  8.370 Total Display time:  0.080

Function used was FASTA [36.3.4 Apr, 2011]
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