FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB4178, 345 aa 1>>>pF1KB4178 345 - 345 aa - 345 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.9481+/-0.000792; mu= 9.4667+/- 0.048 mean_var=110.2949+/-21.276, 0's: 0 Z-trim(111.3): 20 B-trim: 34 in 1/49 Lambda= 0.122123 statistics sampled from 12245 (12258) to 12245 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.729), E-opt: 0.2 (0.377), width: 16 Scan time: 3.090 The best scores are: opt bits E(32554) CCDS31880.1 TMPO gene_id:7112|Hs108|chr12 ( 345) 2234 403.9 1e-112 CCDS76589.1 TMPO gene_id:7112|Hs108|chr12 ( 414) 1455 266.7 2.5e-71 CCDS31879.1 TMPO gene_id:7112|Hs108|chr12 ( 454) 1427 261.8 8.1e-70 CCDS9064.1 TMPO gene_id:7112|Hs108|chr12 ( 694) 1226 226.4 5.3e-59 >>CCDS31880.1 TMPO gene_id:7112|Hs108|chr12 (345 aa) initn: 2234 init1: 2234 opt: 2234 Z-score: 2137.1 bits: 403.9 E(32554): 1e-112 Smith-Waterman score: 2234; 100.0% identity (100.0% similar) in 345 aa overlap (1-345:1-345) 10 20 30 40 50 60 pF1KB4 MPEFLEDPSVLTKDKLKSELVANNVTLPAGEQRKDVYVQLYLQHLTARNRPPLPAGTNSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 MPEFLEDPSVLTKDKLKSELVANNVTLPAGEQRKDVYVQLYLQHLTARNRPPLPAGTNSK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 GPPDFSSDEEREPTPVLGSGAAAAGRSRAAVGRKATKKTDKPRQEDKDDLDVTELTNEDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 GPPDFSSDEEREPTPVLGSGAAAAGRSRAAVGRKATKKTDKPRQEDKDDLDVTELTNEDL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 LDQLVKYGVNPGPIVGTTRKLYEKKLLKLREQGTESRSSTPLPTISSSAENTRQNGSNDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 LDQLVKYGVNPGPIVGTTRKLYEKKLLKLREQGTESRSSTPLPTISSSAENTRQNGSNDS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 DRYSDNEEDSKIELKLEKREPLKGRAKTPVTLKQRRVEHNQVGEKTEERRVERDILKEMF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 DRYSDNEEDSKIELKLEKREPLKGRAKTPVTLKQRRVEHNQVGEKTEERRVERDILKEMF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB4 PYEASTPTGISASCRRPIKGAAGRPLELSDFRMEESFSSKYVPKYVPLADVKSEKTKKGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 PYEASTPTGISASCRRPIKGAAGRPLELSDFRMEESFSSKYVPKYVPLADVKSEKTKKGR 250 260 270 280 290 300 310 320 330 340 pF1KB4 SIPVWIKILLFVVVAVFLFLVYQAMETNQVNPFSNFLHVDPRKSN ::::::::::::::::::::::::::::::::::::::::::::: CCDS31 SIPVWIKILLFVVVAVFLFLVYQAMETNQVNPFSNFLHVDPRKSN 310 320 330 340 >>CCDS76589.1 TMPO gene_id:7112|Hs108|chr12 (414 aa) initn: 1454 init1: 1430 opt: 1455 Z-score: 1394.2 bits: 266.7 E(32554): 2.5e-71 Smith-Waterman score: 1847; 81.7% identity (81.7% similar) in 377 aa overlap (1-308:1-377) 10 20 30 40 50 60 pF1KB4 MPEFLEDPSVLTKDKLKSELVANNVTLPAGEQRKDVYVQLYLQHLTARNRPPLPAGTNSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 MPEFLEDPSVLTKDKLKSELVANNVTLPAGEQRKDVYVQLYLQHLTARNRPPLPAGTNSK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 GPPDFSSDEEREPTPVLGSGAAAAGRSRAAVGRKATKKTDKPRQEDKDDLDVTELTNEDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 GPPDFSSDEEREPTPVLGSGAAAAGRSRAAVGRKATKKTDKPRQEDKDDLDVTELTNEDL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 LDQLVKYGVNPGPIVGTTRKLYEKKLLKLREQGTESRSSTPLPTISSSAENTRQNGSNDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 LDQLVKYGVNPGPIVGTTRKLYEKKLLKLREQGTESRSSTPLPTISSSAENTRQNGSNDS 130 140 150 160 170 180 190 200 210 220 pF1KB4 DRYSDNEEDSKIELKLEKREPLKGRAKTPVTLKQRRVEHNQV------------------ :::::::::::::::::::::::::::::::::::::::::: CCDS76 DRYSDNEEDSKIELKLEKREPLKGRAKTPVTLKQRRVEHNQVETSEHFRIDGPVISESTP 190 200 210 220 230 240 230 pF1KB4 ---------------------------------------------------GEKTEERRV ::::::::: CCDS76 IAETIMASSNESLVVNRVTGNFKHASPILPITEFSDIPRRAPKKPLTRAEVGEKTEERRV 250 260 270 280 290 300 240 250 260 270 280 290 pF1KB4 ERDILKEMFPYEASTPTGISASCRRPIKGAAGRPLELSDFRMEESFSSKYVPKYVPLADV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 ERDILKEMFPYEASTPTGISASCRRPIKGAAGRPLELSDFRMEESFSSKYVPKYVPLADV 310 320 330 340 350 360 300 310 320 330 340 pF1KB4 KSEKTKKGRSIPVWIKILLFVVVAVFLFLVYQAMETNQVNPFSNFLHVDPRKSN ::::::::::::::::: CCDS76 KSEKTKKGRSIPVWIKILLFVVVAVFLFLVYQAMETNQVNPFSNFLHVDPRKSN 370 380 390 400 410 >>CCDS31879.1 TMPO gene_id:7112|Hs108|chr12 (454 aa) initn: 1449 init1: 1425 opt: 1427 Z-score: 1366.9 bits: 261.8 E(32554): 8.1e-70 Smith-Waterman score: 1505; 71.1% identity (71.1% similar) in 377 aa overlap (1-268:1-377) 10 20 30 40 50 60 pF1KB4 MPEFLEDPSVLTKDKLKSELVANNVTLPAGEQRKDVYVQLYLQHLTARNRPPLPAGTNSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 MPEFLEDPSVLTKDKLKSELVANNVTLPAGEQRKDVYVQLYLQHLTARNRPPLPAGTNSK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 GPPDFSSDEEREPTPVLGSGAAAAGRSRAAVGRKATKKTDKPRQEDKDDLDVTELTNEDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 GPPDFSSDEEREPTPVLGSGAAAAGRSRAAVGRKATKKTDKPRQEDKDDLDVTELTNEDL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 LDQLVKYGVNPGPIVGTTRKLYEKKLLKLREQGTESRSSTPLPTISSSAENTRQNGSNDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 LDQLVKYGVNPGPIVGTTRKLYEKKLLKLREQGTESRSSTPLPTISSSAENTRQNGSNDS 130 140 150 160 170 180 190 200 210 220 pF1KB4 DRYSDNEEDSKIELKLEKREPLKGRAKTPVTLKQRRVEHNQ------------------- ::::::::::::::::::::::::::::::::::::::::: CCDS31 DRYSDNEEDSKIELKLEKREPLKGRAKTPVTLKQRRVEHNQSYSQAGITETEWTSGSSKG 190 200 210 220 230 240 pF1KB4 ------------------------------------------------------------ CCDS31 GPLQALTRESTRGSRRTPRKRVETSEHFRIDGPVISESTPIAETIMASSNESLVVNRVTG 250 260 270 280 290 300 230 240 250 pF1KB4 ------------------------------VGEKTEERRVERDILKEMFPYEASTPTGIS :::::::::::::::::::::::::::::: CCDS31 NFKHASPILPITEFSDIPRRAPKKPLTRAEVGEKTEERRVERDILKEMFPYEASTPTGIS 310 320 330 340 350 360 260 270 280 290 300 310 pF1KB4 ASCRRPIKGAAGRPLELSDFRMEESFSSKYVPKYVPLADVKSEKTKKGRSIPVWIKILLF ::::::::::::::::: CCDS31 ASCRRPIKGAAGRPLELSDFRMEESFSSKYVPKYVPLADVKSEKTKKGRSIPVWIKILLF 370 380 390 400 410 420 >-- initn: 501 init1: 501 opt: 501 Z-score: 485.2 bits: 98.6 E(32554): 1.1e-20 Smith-Waterman score: 501; 100.0% identity (100.0% similar) in 77 aa overlap (269-345:378-454) 240 250 260 270 280 290 pF1KB4 MFPYEASTPTGISASCRRPIKGAAGRPLELSDFRMEESFSSKYVPKYVPLADVKSEKTKK :::::::::::::::::::::::::::::: CCDS31 MFPYEASTPTGISASCRRPIKGAAGRPLELSDFRMEESFSSKYVPKYVPLADVKSEKTKK 350 360 370 380 390 400 300 310 320 330 340 pF1KB4 GRSIPVWIKILLFVVVAVFLFLVYQAMETNQVNPFSNFLHVDPRKSN ::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 GRSIPVWIKILLFVVVAVFLFLVYQAMETNQVNPFSNFLHVDPRKSN 410 420 430 440 450 >>CCDS9064.1 TMPO gene_id:7112|Hs108|chr12 (694 aa) initn: 1252 init1: 1226 opt: 1226 Z-score: 1172.7 bits: 226.4 E(32554): 5.3e-59 Smith-Waterman score: 1226; 97.9% identity (98.5% similar) in 195 aa overlap (1-195:1-195) 10 20 30 40 50 60 pF1KB4 MPEFLEDPSVLTKDKLKSELVANNVTLPAGEQRKDVYVQLYLQHLTARNRPPLPAGTNSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS90 MPEFLEDPSVLTKDKLKSELVANNVTLPAGEQRKDVYVQLYLQHLTARNRPPLPAGTNSK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB4 GPPDFSSDEEREPTPVLGSGAAAAGRSRAAVGRKATKKTDKPRQEDKDDLDVTELTNEDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS90 GPPDFSSDEEREPTPVLGSGAAAAGRSRAAVGRKATKKTDKPRQEDKDDLDVTELTNEDL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB4 LDQLVKYGVNPGPIVGTTRKLYEKKLLKLREQGTESRSSTPLPTISSSAENTRQNGSNDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS90 LDQLVKYGVNPGPIVGTTRKLYEKKLLKLREQGTESRSSTPLPTISSSAENTRQNGSNDS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB4 DRYSDNEEDSKIELKLEKREPLKGRAKTPVTLKQRRVEHNQVGEKTEERRVERDILKEMF :::::::: .: : : CCDS90 DRYSDNEEGKKKEHKKVKSTRDIVPFSELGTTPSGGGFFQGISFPEISTRPPLGSTELQA 190 200 210 220 230 240 345 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 05:41:48 2016 done: Sat Nov 5 05:41:49 2016 Total Scan time: 3.090 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]