Result of FASTA (omim) for
pF1KB4178
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB4178, 345 aa
1>>>pF1KB4178 345 - 345 aa - 345 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.1263+/-0.000329; mu= 8.4842+/- 0.021
mean_var=117.9611+/-23.664, 0's: 0 Z-trim(118.7): 22 B-trim: 1104 in 2/53
Lambda= 0.118088
statistics sampled from 31902 (31924) to 31902 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.721), E-opt: 0.2 (0.374), width: 16
Scan time: 9.070
The best scores are: opt bits E(85289)
NP_001027455 (OMIM: 188380,613740) thymopoietin is ( 345) 2234 391.2 1.8e-108
NP_001294904 (OMIM: 188380,613740) thymopoietin is ( 414) 1455 258.5 1.9e-68
XP_005269189 (OMIM: 188380,613740) PREDICTED: thym ( 382) 1430 254.2 3.3e-67
NP_001027454 (OMIM: 188380,613740) thymopoietin is ( 454) 1427 253.7 5.5e-67
NP_003267 (OMIM: 188380,613740) thymopoietin isofo ( 694) 1226 219.6 1.6e-56
>>NP_001027455 (OMIM: 188380,613740) thymopoietin isofor (345 aa)
initn: 2234 init1: 2234 opt: 2234 Z-score: 2068.4 bits: 391.2 E(85289): 1.8e-108
Smith-Waterman score: 2234; 100.0% identity (100.0% similar) in 345 aa overlap (1-345:1-345)
10 20 30 40 50 60
pF1KB4 MPEFLEDPSVLTKDKLKSELVANNVTLPAGEQRKDVYVQLYLQHLTARNRPPLPAGTNSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPEFLEDPSVLTKDKLKSELVANNVTLPAGEQRKDVYVQLYLQHLTARNRPPLPAGTNSK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 GPPDFSSDEEREPTPVLGSGAAAAGRSRAAVGRKATKKTDKPRQEDKDDLDVTELTNEDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPPDFSSDEEREPTPVLGSGAAAAGRSRAAVGRKATKKTDKPRQEDKDDLDVTELTNEDL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 LDQLVKYGVNPGPIVGTTRKLYEKKLLKLREQGTESRSSTPLPTISSSAENTRQNGSNDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDQLVKYGVNPGPIVGTTRKLYEKKLLKLREQGTESRSSTPLPTISSSAENTRQNGSNDS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 DRYSDNEEDSKIELKLEKREPLKGRAKTPVTLKQRRVEHNQVGEKTEERRVERDILKEMF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DRYSDNEEDSKIELKLEKREPLKGRAKTPVTLKQRRVEHNQVGEKTEERRVERDILKEMF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 PYEASTPTGISASCRRPIKGAAGRPLELSDFRMEESFSSKYVPKYVPLADVKSEKTKKGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PYEASTPTGISASCRRPIKGAAGRPLELSDFRMEESFSSKYVPKYVPLADVKSEKTKKGR
250 260 270 280 290 300
310 320 330 340
pF1KB4 SIPVWIKILLFVVVAVFLFLVYQAMETNQVNPFSNFLHVDPRKSN
:::::::::::::::::::::::::::::::::::::::::::::
NP_001 SIPVWIKILLFVVVAVFLFLVYQAMETNQVNPFSNFLHVDPRKSN
310 320 330 340
>>NP_001294904 (OMIM: 188380,613740) thymopoietin isofor (414 aa)
initn: 1454 init1: 1430 opt: 1455 Z-score: 1350.0 bits: 258.5 E(85289): 1.9e-68
Smith-Waterman score: 1847; 81.7% identity (81.7% similar) in 377 aa overlap (1-308:1-377)
10 20 30 40 50 60
pF1KB4 MPEFLEDPSVLTKDKLKSELVANNVTLPAGEQRKDVYVQLYLQHLTARNRPPLPAGTNSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPEFLEDPSVLTKDKLKSELVANNVTLPAGEQRKDVYVQLYLQHLTARNRPPLPAGTNSK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 GPPDFSSDEEREPTPVLGSGAAAAGRSRAAVGRKATKKTDKPRQEDKDDLDVTELTNEDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPPDFSSDEEREPTPVLGSGAAAAGRSRAAVGRKATKKTDKPRQEDKDDLDVTELTNEDL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 LDQLVKYGVNPGPIVGTTRKLYEKKLLKLREQGTESRSSTPLPTISSSAENTRQNGSNDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDQLVKYGVNPGPIVGTTRKLYEKKLLKLREQGTESRSSTPLPTISSSAENTRQNGSNDS
130 140 150 160 170 180
190 200 210 220
pF1KB4 DRYSDNEEDSKIELKLEKREPLKGRAKTPVTLKQRRVEHNQV------------------
::::::::::::::::::::::::::::::::::::::::::
NP_001 DRYSDNEEDSKIELKLEKREPLKGRAKTPVTLKQRRVEHNQVETSEHFRIDGPVISESTP
190 200 210 220 230 240
230
pF1KB4 ---------------------------------------------------GEKTEERRV
:::::::::
NP_001 IAETIMASSNESLVVNRVTGNFKHASPILPITEFSDIPRRAPKKPLTRAEVGEKTEERRV
250 260 270 280 290 300
240 250 260 270 280 290
pF1KB4 ERDILKEMFPYEASTPTGISASCRRPIKGAAGRPLELSDFRMEESFSSKYVPKYVPLADV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ERDILKEMFPYEASTPTGISASCRRPIKGAAGRPLELSDFRMEESFSSKYVPKYVPLADV
310 320 330 340 350 360
300 310 320 330 340
pF1KB4 KSEKTKKGRSIPVWIKILLFVVVAVFLFLVYQAMETNQVNPFSNFLHVDPRKSN
:::::::::::::::::
NP_001 KSEKTKKGRSIPVWIKILLFVVVAVFLFLVYQAMETNQVNPFSNFLHVDPRKSN
370 380 390 400 410
>--
initn: 239 init1: 239 opt: 239 Z-score: 230.4 bits: 51.3 E(85289): 4.3e-06
Smith-Waterman score: 239; 100.0% identity (100.0% similar) in 37 aa overlap (309-345:378-414)
280 290 300 310 320 330
pF1KB4 SKYVPKYVPLADVKSEKTKKGRSIPVWIKILLFVVVAVFLFLVYQAMETNQVNPFSNFLH
::::::::::::::::::::::::::::::
NP_001 SKYVPKYVPLADVKSEKTKKGRSIPVWIKILLFVVVAVFLFLVYQAMETNQVNPFSNFLH
350 360 370 380 390 400
340
pF1KB4 VDPRKSN
:::::::
NP_001 VDPRKSN
410
>>XP_005269189 (OMIM: 188380,613740) PREDICTED: thymopoi (382 aa)
initn: 1454 init1: 1430 opt: 1430 Z-score: 1327.5 bits: 254.2 E(85289): 3.3e-67
Smith-Waterman score: 2115; 90.2% identity (90.2% similar) in 377 aa overlap (1-340:1-377)
10 20 30 40 50 60
pF1KB4 MPEFLEDPSVLTKDKLKSELVANNVTLPAGEQRKDVYVQLYLQHLTARNRPPLPAGTNSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MPEFLEDPSVLTKDKLKSELVANNVTLPAGEQRKDVYVQLYLQHLTARNRPPLPAGTNSK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 GPPDFSSDEEREPTPVLGSGAAAAGRSRAAVGRKATKKTDKPRQEDKDDLDVTELTNEDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GPPDFSSDEEREPTPVLGSGAAAAGRSRAAVGRKATKKTDKPRQEDKDDLDVTELTNEDL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 LDQLVKYGVNPGPIVGTTRKLYEKKLLKLREQGTESRSSTPLPTISSSAENTRQNGSNDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LDQLVKYGVNPGPIVGTTRKLYEKKLLKLREQGTESRSSTPLPTISSSAENTRQNGSNDS
130 140 150 160 170 180
190 200 210 220
pF1KB4 DRYSDNEEDSKIELKLEKREPLKGRAKTPVTLKQRRVEHNQV------------------
::::::::::::::::::::::::::::::::::::::::::
XP_005 DRYSDNEEDSKIELKLEKREPLKGRAKTPVTLKQRRVEHNQVVNRVTGNFKHASPILPIT
190 200 210 220 230 240
230 240 250 260
pF1KB4 -------------------GEKTEERRVERDILKEMFPYEASTPTGISASCRRPIKGAAG
:::::::::::::::::::::::::::::::::::::::::
XP_005 EFSDIPRRAPKKPLTRAEVGEKTEERRVERDILKEMFPYEASTPTGISASCRRPIKGAAG
250 260 270 280 290 300
270 280 290 300 310 320
pF1KB4 RPLELSDFRMEESFSSKYVPKYVPLADVKSEKTKKGRSIPVWIKILLFVVVAVFLFLVYQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RPLELSDFRMEESFSSKYVPKYVPLADVKSEKTKKGRSIPVWIKILLFVVVAVFLFLVYQ
310 320 330 340 350 360
330 340
pF1KB4 AMETNQVNPFSNFLHVDPRKSN
:::::::::::::::::
XP_005 AMETNQVNPFSNFLHVDPRKSN
370 380
>>NP_001027454 (OMIM: 188380,613740) thymopoietin isofor (454 aa)
initn: 1449 init1: 1425 opt: 1427 Z-score: 1323.6 bits: 253.7 E(85289): 5.5e-67
Smith-Waterman score: 1505; 71.1% identity (71.1% similar) in 377 aa overlap (1-268:1-377)
10 20 30 40 50 60
pF1KB4 MPEFLEDPSVLTKDKLKSELVANNVTLPAGEQRKDVYVQLYLQHLTARNRPPLPAGTNSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPEFLEDPSVLTKDKLKSELVANNVTLPAGEQRKDVYVQLYLQHLTARNRPPLPAGTNSK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 GPPDFSSDEEREPTPVLGSGAAAAGRSRAAVGRKATKKTDKPRQEDKDDLDVTELTNEDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPPDFSSDEEREPTPVLGSGAAAAGRSRAAVGRKATKKTDKPRQEDKDDLDVTELTNEDL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 LDQLVKYGVNPGPIVGTTRKLYEKKLLKLREQGTESRSSTPLPTISSSAENTRQNGSNDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDQLVKYGVNPGPIVGTTRKLYEKKLLKLREQGTESRSSTPLPTISSSAENTRQNGSNDS
130 140 150 160 170 180
190 200 210 220
pF1KB4 DRYSDNEEDSKIELKLEKREPLKGRAKTPVTLKQRRVEHNQ-------------------
:::::::::::::::::::::::::::::::::::::::::
NP_001 DRYSDNEEDSKIELKLEKREPLKGRAKTPVTLKQRRVEHNQSYSQAGITETEWTSGSSKG
190 200 210 220 230 240
pF1KB4 ------------------------------------------------------------
NP_001 GPLQALTRESTRGSRRTPRKRVETSEHFRIDGPVISESTPIAETIMASSNESLVVNRVTG
250 260 270 280 290 300
230 240 250
pF1KB4 ------------------------------VGEKTEERRVERDILKEMFPYEASTPTGIS
::::::::::::::::::::::::::::::
NP_001 NFKHASPILPITEFSDIPRRAPKKPLTRAEVGEKTEERRVERDILKEMFPYEASTPTGIS
310 320 330 340 350 360
260 270 280 290 300 310
pF1KB4 ASCRRPIKGAAGRPLELSDFRMEESFSSKYVPKYVPLADVKSEKTKKGRSIPVWIKILLF
:::::::::::::::::
NP_001 ASCRRPIKGAAGRPLELSDFRMEESFSSKYVPKYVPLADVKSEKTKKGRSIPVWIKILLF
370 380 390 400 410 420
>--
initn: 501 init1: 501 opt: 501 Z-score: 471.0 bits: 96.0 E(85289): 1.7e-19
Smith-Waterman score: 501; 100.0% identity (100.0% similar) in 77 aa overlap (269-345:378-454)
240 250 260 270 280 290
pF1KB4 MFPYEASTPTGISASCRRPIKGAAGRPLELSDFRMEESFSSKYVPKYVPLADVKSEKTKK
::::::::::::::::::::::::::::::
NP_001 MFPYEASTPTGISASCRRPIKGAAGRPLELSDFRMEESFSSKYVPKYVPLADVKSEKTKK
350 360 370 380 390 400
300 310 320 330 340
pF1KB4 GRSIPVWIKILLFVVVAVFLFLVYQAMETNQVNPFSNFLHVDPRKSN
:::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GRSIPVWIKILLFVVVAVFLFLVYQAMETNQVNPFSNFLHVDPRKSN
410 420 430 440 450
>>NP_003267 (OMIM: 188380,613740) thymopoietin isoform a (694 aa)
initn: 1252 init1: 1226 opt: 1226 Z-score: 1135.7 bits: 219.6 E(85289): 1.6e-56
Smith-Waterman score: 1226; 97.9% identity (98.5% similar) in 195 aa overlap (1-195:1-195)
10 20 30 40 50 60
pF1KB4 MPEFLEDPSVLTKDKLKSELVANNVTLPAGEQRKDVYVQLYLQHLTARNRPPLPAGTNSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MPEFLEDPSVLTKDKLKSELVANNVTLPAGEQRKDVYVQLYLQHLTARNRPPLPAGTNSK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 GPPDFSSDEEREPTPVLGSGAAAAGRSRAAVGRKATKKTDKPRQEDKDDLDVTELTNEDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 GPPDFSSDEEREPTPVLGSGAAAAGRSRAAVGRKATKKTDKPRQEDKDDLDVTELTNEDL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 LDQLVKYGVNPGPIVGTTRKLYEKKLLKLREQGTESRSSTPLPTISSSAENTRQNGSNDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LDQLVKYGVNPGPIVGTTRKLYEKKLLKLREQGTESRSSTPLPTISSSAENTRQNGSNDS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 DRYSDNEEDSKIELKLEKREPLKGRAKTPVTLKQRRVEHNQVGEKTEERRVERDILKEMF
:::::::: .: : :
NP_003 DRYSDNEEGKKKEHKKVKSTRDIVPFSELGTTPSGGGFFQGISFPEISTRPPLGSTELQA
190 200 210 220 230 240
345 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 05:41:49 2016 done: Sat Nov 5 05:41:50 2016
Total Scan time: 9.070 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]